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Conserved domains on  [gi|514351510|gb|AGO49936|]
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Toll-like receptor 7, partial [Apteryx mantelli mantelli]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 11469232)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

Gene Ontology:  GO:0005515
PubMed:  11751054|7583641|14747988
SCOP:  4003523

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
1-223 5.85e-13

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 68.42  E-value: 5.85e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351510   1 SLKSNNLTYIPPNLSS--TLKELYIYNNMIQVIQEhDLIALHNLEILDLSGNcprcynapypctpcpkgTIEIHPKAFQS 78
Cdd:COG4886  119 DLSGNQLTDLPEELANltNLKELDLSNNQLTDLPE-PLGNLTNLKSLDLSNN-----------------QLTDLPEELGN 180

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351510  79 LKQLKILRLHSNSLQRiLSSWFENTRNLKELDLSQNFLaKEIGDAqfLKLIPSLVELDLSFNfqlqmyspslNLSK--TF 156
Cdd:COG4886  181 LTNLKELDLSNNQITD-LPEPLGNLTNLEELDLSGNQL-TDLPEP--LANLTNLETLDLSNN----------QLTDlpEL 246

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 514351510 157 SSLVNLEILRLRGyvfkeLKQENLDPLLHLRNLTVLDLGTNFIKVADLKVFKKFPALKFIDLSVNKI 223
Cdd:COG4886  247 GNLTNLEELDLSN-----NQLTDLPPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLL 308
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
1-223 5.85e-13

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 68.42  E-value: 5.85e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351510   1 SLKSNNLTYIPPNLSS--TLKELYIYNNMIQVIQEhDLIALHNLEILDLSGNcprcynapypctpcpkgTIEIHPKAFQS 78
Cdd:COG4886  119 DLSGNQLTDLPEELANltNLKELDLSNNQLTDLPE-PLGNLTNLKSLDLSNN-----------------QLTDLPEELGN 180

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351510  79 LKQLKILRLHSNSLQRiLSSWFENTRNLKELDLSQNFLaKEIGDAqfLKLIPSLVELDLSFNfqlqmyspslNLSK--TF 156
Cdd:COG4886  181 LTNLKELDLSNNQITD-LPEPLGNLTNLEELDLSGNQL-TDLPEP--LANLTNLETLDLSNN----------QLTDlpEL 246

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 514351510 157 SSLVNLEILRLRGyvfkeLKQENLDPLLHLRNLTVLDLGTNFIKVADLKVFKKFPALKFIDLSVNKI 223
Cdd:COG4886  247 GNLTNLEELDLSN-----NQLTDLPPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLL 308
LRR_12 pfam18837
Leucine-rich repeat; This Pfam entry includes some LRRs that fail to be detected with the ...
 189-218 1.28e-08

Leucine-rich repeat; This Pfam entry includes some LRRs that fail to be detected with the pfam00560 model. This entry represents one repeat unit.


Pssm-ID: 408607  Cd Length: 30  Bit Score: 49.65  E-value: 1.28e-08
                          10        20        30
                  ....*....|....*....|....*....|
gi 514351510  189 LTVLDLGTNFIKVADLKVFKKFPALKFIDL 218
Cdd:pfam18837   1 LQTLHLQMNFINQAQLSIFGAFPGLRFVDL 30
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 2-224 8.17e-08

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 53.31  E-value: 8.17e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351510   2 LKSNNLT-YIPPNLSS--TLKELYIYNNMIQVIQEHDLIALHNLEILDLSGNCprcYNAPYPCTPCPKGTI--------- 69
Cdd:PLN00113 315 LFSNNFTgKIPVALTSlpRLQVLQLWSNKFSGEIPKNLGKHNNLTVLDLSTNN---LTGEIPEGLCSSGNLfklilfsns 391

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351510  70 ---EIhPKAFQSLKQLKILRLHSNSLQRILSSWFENTRNLKELDLSQNFLAKEIGDAQFlkLIPSLVELDLS---FNFQL 143
Cdd:PLN00113 392 legEI-PKSLGACRSLRRVRLQDNSFSGELPSEFTKLPLVYFLDISNNNLQGRINSRKW--DMPSLQMLSLArnkFFGGL 468

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351510 144 QMYSPSLNLSK--------------TFSSLVNLEILRLRGyvfKELKQENLDPLLHLRNLTVLDLGTNFIKVADLKVFKK 209
Cdd:PLN00113 469 PDSFGSKRLENldlsrnqfsgavprKLGSLSELMQLKLSE---NKLSGEIPDELSSCKKLVSLDLSHNQLSGQIPASFSE 545

                        250
                 ....*....|....*
gi 514351510 210 FPALKFIDLSVNKIS 224
Cdd:PLN00113 546 MPVLSQLDLSQNQLS 560
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 6-194 1.19e-07

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 51.33  E-value: 1.19e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351510   6 NLTYIPpNLSST--LKELYIYNNMIQVIQehDLIALHNLEILDLSGNCPRCynapypctpcpkgtIEihpkAFQSLKQLK 83
Cdd:cd21340   13 NITKID-NLSLCknLKVLYLYDNKITKIE--NLEFLTNLTHLYLQNNQIEK--------------IE----NLENLVNLK 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351510  84 ILRLHSNSLQRIlsSWFENTRNLKELDLSQNFLAKE---IGDAQFLKLI-PSLVELDLSFNfQLQMYSPslnlsktFSSL 159
Cdd:cd21340   72 KLYLGGNRISVV--EGLENLTNLEELHIENQRLPPGeklTFDPRSLAALsNSLRVLNISGN-NIDSLEP-------LAPL 141

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 514351510 160 VNLEILRLRGYVFKELKqENLDPLLHLRNLTVLDL 194
Cdd:cd21340  142 RNLEQLDASNNQISDLE-ELLDLLSSWPSLRELDL 175
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
1-223 5.85e-13

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 68.42  E-value: 5.85e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351510   1 SLKSNNLTYIPPNLSS--TLKELYIYNNMIQVIQEhDLIALHNLEILDLSGNcprcynapypctpcpkgTIEIHPKAFQS 78
Cdd:COG4886  119 DLSGNQLTDLPEELANltNLKELDLSNNQLTDLPE-PLGNLTNLKSLDLSNN-----------------QLTDLPEELGN 180

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351510  79 LKQLKILRLHSNSLQRiLSSWFENTRNLKELDLSQNFLaKEIGDAqfLKLIPSLVELDLSFNfqlqmyspslNLSK--TF 156
Cdd:COG4886  181 LTNLKELDLSNNQITD-LPEPLGNLTNLEELDLSGNQL-TDLPEP--LANLTNLETLDLSNN----------QLTDlpEL 246

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 514351510 157 SSLVNLEILRLRGyvfkeLKQENLDPLLHLRNLTVLDLGTNFIKVADLKVFKKFPALKFIDLSVNKI 223
Cdd:COG4886  247 GNLTNLEELDLSN-----NQLTDLPPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLL 308
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
18-224 1.98e-12

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 66.50  E-value: 1.98e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351510  18 LKELYIYNNMiqviqehDLIALHNLEILDLSGNcprcynapypctpcpkgTIEIHPKAFQSLKQLKILRLHSNSLQRILS 97
Cdd:COG4886   98 LTELDLSGNE-------ELSNLTNLESLDLSGN-----------------QLTDLPEELANLTNLKELDLSNNQLTDLPE 153

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351510  98 SWFENTrNLKELDLSQNFLaKEIGDAqfLKLIPSLVELDLSFNfQLQmyspslNLSKTFSSLVNLEILRLRGYVFKELKq 177
Cdd:COG4886  154 PLGNLT-NLKSLDLSNNQL-TDLPEE--LGNLTNLKELDLSNN-QIT------DLPEPLGNLTNLEELDLSGNQLTDLP- 221

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 514351510 178 enlDPLLHLRNLTVLDLGTNfiKVADLKVFKKFPALKFIDLSVNKIS 224
Cdd:COG4886  222 ---EPLANLTNLETLDLSNN--QLTDLPELGNLTNLEELDLSNNQLT 263
LRR_12 pfam18837
Leucine-rich repeat; This Pfam entry includes some LRRs that fail to be detected with the ...
 189-218 1.28e-08

Leucine-rich repeat; This Pfam entry includes some LRRs that fail to be detected with the pfam00560 model. This entry represents one repeat unit.


Pssm-ID: 408607  Cd Length: 30  Bit Score: 49.65  E-value: 1.28e-08
                          10        20        30
                  ....*....|....*....|....*....|
gi 514351510  189 LTVLDLGTNFIKVADLKVFKKFPALKFIDL 218
Cdd:pfam18837   1 LQTLHLQMNFINQAQLSIFGAFPGLRFVDL 30
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 2-224 8.17e-08

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 53.31  E-value: 8.17e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351510   2 LKSNNLT-YIPPNLSS--TLKELYIYNNMIQVIQEHDLIALHNLEILDLSGNCprcYNAPYPCTPCPKGTI--------- 69
Cdd:PLN00113 315 LFSNNFTgKIPVALTSlpRLQVLQLWSNKFSGEIPKNLGKHNNLTVLDLSTNN---LTGEIPEGLCSSGNLfklilfsns 391

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351510  70 ---EIhPKAFQSLKQLKILRLHSNSLQRILSSWFENTRNLKELDLSQNFLAKEIGDAQFlkLIPSLVELDLS---FNFQL 143
Cdd:PLN00113 392 legEI-PKSLGACRSLRRVRLQDNSFSGELPSEFTKLPLVYFLDISNNNLQGRINSRKW--DMPSLQMLSLArnkFFGGL 468

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351510 144 QMYSPSLNLSK--------------TFSSLVNLEILRLRGyvfKELKQENLDPLLHLRNLTVLDLGTNFIKVADLKVFKK 209
Cdd:PLN00113 469 PDSFGSKRLENldlsrnqfsgavprKLGSLSELMQLKLSE---NKLSGEIPDELSSCKKLVSLDLSHNQLSGQIPASFSE 545

                        250
                 ....*....|....*
gi 514351510 210 FPALKFIDLSVNKIS 224
Cdd:PLN00113 546 MPVLSQLDLSQNQLS 560
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 6-194 1.19e-07

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 51.33  E-value: 1.19e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351510   6 NLTYIPpNLSST--LKELYIYNNMIQVIQehDLIALHNLEILDLSGNCPRCynapypctpcpkgtIEihpkAFQSLKQLK 83
Cdd:cd21340   13 NITKID-NLSLCknLKVLYLYDNKITKIE--NLEFLTNLTHLYLQNNQIEK--------------IE----NLENLVNLK 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351510  84 ILRLHSNSLQRIlsSWFENTRNLKELDLSQNFLAKE---IGDAQFLKLI-PSLVELDLSFNfQLQMYSPslnlsktFSSL 159
Cdd:cd21340   72 KLYLGGNRISVV--EGLENLTNLEELHIENQRLPPGeklTFDPRSLAALsNSLRVLNISGN-NIDSLEP-------LAPL 141

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 514351510 160 VNLEILRLRGYVFKELKqENLDPLLHLRNLTVLDL 194
Cdd:cd21340  142 RNLEQLDASNNQISDLE-ELLDLLSSWPSLRELDL 175
LRR_8 pfam13855
Leucine rich repeat;
81-140 7.68e-07

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 45.21  E-value: 7.68e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351510   81 QLKILRLHSNSLQRILSSWFENTRNLKELDLSQNFLaKEIGDAQFLKLiPSLVELDLSFN 140
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLL-TTLSPGAFSGL-PSLRYLDLSGN 59
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 2-169 1.68e-05

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 44.78  E-value: 1.68e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351510   2 LKSNNLTYIPpNLSST--LKELYIYNNMIQVIQehDLIALHNLEILDLSGNCPRCynapypctpcpkgtIEihpkAFQSL 79
Cdd:cd21340   31 LYDNKITKIE-NLEFLtnLTHLYLQNNQIEKIE--NLENLVNLKKLYLGGNRISV--------------VE----GLENL 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351510  80 KQLKILRLHSNSLQRILSSWFEN------TRNLKELDLSQNflakEIGDAQFLKLIPSLVELDLSFNfQLQMYSpslNLS 153
Cdd:cd21340   90 TNLEELHIENQRLPPGEKLTFDPrslaalSNSLRVLNISGN----NIDSLEPLAPLRNLEQLDASNN-QISDLE---ELL 161

                        170
                 ....*....|....*.
gi 514351510 154 KTFSSLVNLEILRLRG 169
Cdd:cd21340  162 DLLSSWPSLRELDLTG 177
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 1-197 2.58e-05

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 45.61  E-value: 2.58e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351510   1 SLKSNNLT-YIPPNLSS--TLKELYI-YNNMIQVIqEHDLIALHNLEILDLsgncprCYNAPypctpcpKGTIeihPKAF 76
Cdd:PLN00113 194 TLASNQLVgQIPRELGQmkSLKWIYLgYNNLSGEI-PYEIGGLTSLNHLDL------VYNNL-------TGPI---PSSL 256

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351510  77 QSLKQLKILRLHSNSLQRILSSWFENTRNLKELDLSQNFLAKEIGDaqflkLIPSLVELDLsfnfqLQMYSPSLN--LSK 154
Cdd:PLN00113 257 GNLKNLQYLFLYQNKLSGPIPPSIFSLQKLISLDLSDNSLSGEIPE-----LVIQLQNLEI-----LHLFSNNFTgkIPV 326

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 514351510 155 TFSSLVNLEIL-----RLRGYVFKELKQENldpllhlrNLTVLDLGTN 197
Cdd:PLN00113 327 ALTSLPRLQVLqlwsnKFSGEIPKNLGKHN--------NLTVLDLSTN 366
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 73-238 6.47e-05

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 43.50  E-value: 6.47e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351510  73 PKAFQSLKQLKILRLHSNSLQRILSSWFENTR---NLKELDLSQNFLAKEIGD--AQFLK-LIPSLVELDLSFNfqLQMY 146
Cdd:cd00116   74 LQGLTKGCGLQELDLSDNALGPDGCGVLESLLrssSLQELKLNNNGLGDRGLRllAKGLKdLPPALEKLVLGRN--RLEG 151

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351510 147 SPSLNLSKTFSSLVNLEILRLR---------------GYVFKELKQENLDP--------------LLHLRNLTVLDLGTN 197
Cdd:cd00116  152 ASCEALAKALRANRDLKELNLAnngigdagiralaegLKANCNLEVLDLNNngltdegasalaetLASLKSLEVLNLGDN 231

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 514351510 198 FIKVADLKVFKK-----FPALKFIDLSVNKISPSSGESNCyRFCPN 238
Cdd:cd00116  232 NLTDAGAAALASallspNISLLTLSLSCNDITDDGAKDLA-EVLAE 276
LRR_8 pfam13855
Leucine rich repeat;
71-114 8.93e-05

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 39.43  E-value: 8.93e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 514351510   71 IHPKAFQSLKQLKILRLHSNSLQRILSSWFENTRNLKELDLSQN 114
Cdd:pfam13855  16 LDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGN 59
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 1-199 2.27e-04

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 42.53  E-value: 2.27e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351510   1 SLKSNNLT-YIPPNLSSTLKELYIYNNMIQVIQEHDLIALHNLEILDLSGNcprcynapypctpCPKGTIeihPKAFQSL 79
Cdd:PLN00113 124 NLSNNNFTgSIPRGSIPNLETLDLSNNMLSGEIPNDIGSFSSLKVLDLGGN-------------VLVGKI---PNSLTNL 187

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351510  80 KQLKILRLHSNSLQRILSSWFENTRNLKELDLSQNFLAKEIgDAQFLKLIpSLVELDLSFNfqlqmyspslNLSKTF-SS 158
Cdd:PLN00113 188 TSLEFLTLASNQLVGQIPRELGQMKSLKWIYLGYNNLSGEI-PYEIGGLT-SLNHLDLVYN----------NLTGPIpSS 255

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 514351510 159 LVNLEILRlrgYVFkeLKQENL-----DPLLHLRNLTVLDLGTNFI 199
Cdd:PLN00113 256 LGNLKNLQ---YLF--LYQNKLsgpipPSIFSLQKLISLDLSDNSL 296
LRR_8 pfam13855
Leucine rich repeat;
16-92 4.19e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 37.89  E-value: 4.19e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 514351510   16 STLKELYIYNNMIQVIQEHDLIALHNLEILDLSGNCPRCynapypctpcpkgtieIHPKAFQSLKQLKILRLHSNSL 92
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTT----------------LSPGAFSGLPSLRYLDLSGNRL 61
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 16-140 4.24e-04

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 41.19  E-value: 4.24e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351510  16 STLKELYIYNNMIQV--IQE--HDLIALHNLEILDLSGNCPRCYNAPYPCtpcpkgtieihpKAFQSLKQLKILRLHSNS 91
Cdd:cd00116  165 RDLKELNLANNGIGDagIRAlaEGLKANCNLEVLDLNNNGLTDEGASALA------------ETLASLKSLEVLNLGDNN 232

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351510  92 L-----QRILSSWFENTRNLKELDLSQNflakEIGD------AQFLKLIPSLVELDLSFN 140
Cdd:cd00116  233 LtdagaAALASALLSPNISLLTLSLSCN----DITDdgakdlAEVLAEKESLLELDLRGN 288
LRR_8 pfam13855
Leucine rich repeat;
1-50 4.72e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 37.50  E-value: 4.72e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 514351510    1 SLKSNNLTYIPP----NLSStLKELYIYNNMIQVIQEHDLIALHNLEILDLSGN 50
Cdd:pfam13855   7 DLSNNRLTSLDDgafkGLSN-LKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGN 59
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 35-164 4.22e-03

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 38.68  E-value: 4.22e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351510  35 DLIALHNLEILDLSGNCPrcynapypctpcpKGTIeihPKAFQSLKQLKILRLHSNSLQRILSSWFENTRNLKELDLSQN 114
Cdd:PLN00113 470 DSFGSKRLENLDLSRNQF-------------SGAV---PRKLGSLSELMQLKLSENKLSGEIPDELSSCKKLVSLDLSHN 533

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 514351510 115 FLAKEIGDAqfLKLIPSLVELDLSFNfQLQMYSPSlNLSKTfSSLVNLEI 164
Cdd:PLN00113 534 QLSGQIPAS--FSEMPVLSQLDLSQN-QLSGEIPK-NLGNV-ESLVQVNI 578
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
78-224 5.15e-03

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 37.99  E-value: 5.15e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351510  78 SLKQLKILRLHSNSLQRILSSWFENTRNLKELDLSQNFLAKEIGDAQFLKLIPSLVELDLSFNFQLQMYSPSLNLSKTFS 157
Cdd:COG4886   31 LLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNEELS 110

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 514351510 158 SLVNLEILRLRGYVFKELKQEnldpLLHLRNLTVLDLGTNfiKVADL-KVFKKFPALKFIDLSVNKIS 224
Cdd:COG4886  111 NLTNLESLDLSGNQLTDLPEE----LANLTNLKELDLSNN--QLTDLpEPLGNLTNLKSLDLSNNQLT 172
LRR_8 pfam13855
Leucine rich repeat;
104-169 5.65e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 34.42  E-value: 5.65e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 514351510  104 RNLKELDLSQNFLaKEIGDAQFLKLiPSLVELDLSFNfQLQMYSPslnlsKTFSSLVNLEILRLRG 169
Cdd:pfam13855   1 PNLRSLDLSNNRL-TSLDDGAFKGL-SNLKVLDLSNN-LLTTLSP-----GAFSGLPSLRYLDLSG 58
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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