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Conserved domains on  [gi|512189132|gb|EPE04900|]
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cript family protein [Ophiostoma piceae UAMH 11346]

Protein Classification

cysteine-rich PDZ-binding protein( domain architecture ID 10562978)

cysteine-rich PDZ-binding protein (CRIPT) involved in the cytoskeletal anchoring of DLG4 in excitatory synapses

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Cript pfam10235
Microtubule-associated protein CRIPT; The CRIPT protein is a cytoskeletal protein involved in ...
 43-107 1.09e-19

Microtubule-associated protein CRIPT; The CRIPT protein is a cytoskeletal protein involved in microtubule production. The C-terminal domain is essential for binding to the PDZ3 domain of the SAP90 protein, one of a super-family of PDZ-containing proteins that play an important role in coupling the membrane ion channels with their signalling partners. SAP90 is concentrated in the post synaptic density of glutamatergic neurons.


:

Pssm-ID: 431159  Cd Length: 87  Bit Score: 76.65  E-value: 1.09e-19
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 512189132   43 ATLGQNG---IGKSKLLSKNAKNPYAQYSSSCDKCKVKVSQ-GHKYCHNCSYKEDVCAMCGKPNKKAKS 107
Cdd:pfam10235  15 NTLGESGgrkINENKLLSKKAKNPYAAYSSKCKICKTKVHQpGAKYCQGCAYKKGICAMCGKKLLDTKN 83
 
Name Accession Description Interval E-value
Cript pfam10235
Microtubule-associated protein CRIPT; The CRIPT protein is a cytoskeletal protein involved in ...
 43-107 1.09e-19

Microtubule-associated protein CRIPT; The CRIPT protein is a cytoskeletal protein involved in microtubule production. The C-terminal domain is essential for binding to the PDZ3 domain of the SAP90 protein, one of a super-family of PDZ-containing proteins that play an important role in coupling the membrane ion channels with their signalling partners. SAP90 is concentrated in the post synaptic density of glutamatergic neurons.


Pssm-ID: 431159  Cd Length: 87  Bit Score: 76.65  E-value: 1.09e-19
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 512189132   43 ATLGQNG---IGKSKLLSKNAKNPYAQYSSSCDKCKVKVSQ-GHKYCHNCSYKEDVCAMCGKPNKKAKS 107
Cdd:pfam10235  15 NTLGESGgrkINENKLLSKKAKNPYAAYSSKCKICKTKVHQpGAKYCQGCAYKKGICAMCGKKLLDTKN 83
 
Name Accession Description Interval E-value
Cript pfam10235
Microtubule-associated protein CRIPT; The CRIPT protein is a cytoskeletal protein involved in ...
 43-107 1.09e-19

Microtubule-associated protein CRIPT; The CRIPT protein is a cytoskeletal protein involved in microtubule production. The C-terminal domain is essential for binding to the PDZ3 domain of the SAP90 protein, one of a super-family of PDZ-containing proteins that play an important role in coupling the membrane ion channels with their signalling partners. SAP90 is concentrated in the post synaptic density of glutamatergic neurons.


Pssm-ID: 431159  Cd Length: 87  Bit Score: 76.65  E-value: 1.09e-19
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 512189132   43 ATLGQNG---IGKSKLLSKNAKNPYAQYSSSCDKCKVKVSQ-GHKYCHNCSYKEDVCAMCGKPNKKAKS 107
Cdd:pfam10235  15 NTLGESGgrkINENKLLSKKAKNPYAAYSSKCKICKTKVHQpGAKYCQGCAYKKGICAMCGKKLLDTKN 83
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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