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Conserved domains on  [gi|511278481|ref|WP_016339569|]
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ABC transporter permease [Fusobacterium animalis]

Protein Classification

ABC transporter permease( domain architecture ID 11439449)

ABC transporter permease is the transmembrane (TM) subunit in a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter which generally binds a type 2 PBP; similar to the permease subunit of ABC-type dipeptide/oligopeptide/nickel transport systems

Gene Ontology:  GO:0140359|GO:0042626
PubMed:  25750732|24638992
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 38-260 1.79e-63

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


:

Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 200.34  E-value: 1.79e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511278481  38 GAALIPPSKEHWFGTDDLGIDIFSEICYGAKSTIILSCSSALFAAVGGSIIGMVAGYFGGIFDEILLGIIDFFISVPDLL 117
Cdd:COG1173   49 AARLQPPSAAHWLGTDQLGRDVLSRLLYGARISLLVGLLAVLIALVIGVLLGLLAGYFGGWVDAVLMRLVDVLLAFPSLL 128

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511278481 118 LMVVLGTFLGPSLKNIIFSIVLVSWIMPAKITRSQILRMKQENYIKIAKIYGAGFIHLFLWHFWKQFFSIIMMSVIKLMN 197
Cdd:COG1173  129 LAIALVAVLGPGLLNVILALGLTGWPGYARLVRAQVLSLREREYVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIA 208

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 511278481 198 RAILAEAALSYLGLG-DPLSKSWGMIITRAMDfpniYLTEFWkWWLVYPVIFMVLMVLSIAIIG 260
Cdd:COG1173  209 SAILAEAGLSFLGLGvQPPTPSWGTMLSEGRN----YLLTAP-WLALFPGLAIVLTVLAFNLLG 267
 
Name Accession Description Interval E-value
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 38-260 1.79e-63

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 200.34  E-value: 1.79e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511278481  38 GAALIPPSKEHWFGTDDLGIDIFSEICYGAKSTIILSCSSALFAAVGGSIIGMVAGYFGGIFDEILLGIIDFFISVPDLL 117
Cdd:COG1173   49 AARLQPPSAAHWLGTDQLGRDVLSRLLYGARISLLVGLLAVLIALVIGVLLGLLAGYFGGWVDAVLMRLVDVLLAFPSLL 128

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511278481 118 LMVVLGTFLGPSLKNIIFSIVLVSWIMPAKITRSQILRMKQENYIKIAKIYGAGFIHLFLWHFWKQFFSIIMMSVIKLMN 197
Cdd:COG1173  129 LAIALVAVLGPGLLNVILALGLTGWPGYARLVRAQVLSLREREYVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIA 208

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 511278481 198 RAILAEAALSYLGLG-DPLSKSWGMIITRAMDfpniYLTEFWkWWLVYPVIFMVLMVLSIAIIG 260
Cdd:COG1173  209 SAILAEAGLSFLGLGvQPPTPSWGTMLSEGRN----YLLTAP-WLALFPGLAIVLTVLAFNLLG 267
PRK09881 PRK09881
D,D-dipeptide ABC transporter permease;
39-245 2.12e-35

D,D-dipeptide ABC transporter permease;


Pssm-ID: 182131 [Multi-domain]  Cd Length: 296  Bit Score: 128.40  E-value: 2.12e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511278481  39 AALIPPSKEHWFGTDDLGIDIFSEICYGAKSTIILSCSSALFAAVGGSIIGMVAGYFGGIFDEILLGIIDFFISVPDLLL 118
Cdd:PRK09881  65 ARLLPPSAAHWFGTDEVGRDLFSRVLVGSQQSILAGLVVVAIAGMIGSLLGCLSGVLGGRADAIIMRIMDIMLSIPSLVL 144

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511278481 119 MVVLGTFLGPSLKNIIFSIVLVSWIMPAKITRSQILRMKQENYIKIAKIYGAGFIHLFLWHFWKQFFSIIMMSVIKLMNR 198
Cdd:PRK09881 145 TMALAAALGPSLFNAMLAIAIVRIPFYVRLARGQALVVRQYTYVQAAKTFGASRWHLISWHILRNSLPPLIVQASLDIGS 224

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 511278481 199 AILAEAALSYLGLG-DPLSKSWGMIITRAMDfpniYLTEFWkWWLVYP 245
Cdd:PRK09881 225 AILMAATLGFIGLGaQQPSAEWGAMVANGRN----YVLDQW-WYCAFP 267
nickel_nikC TIGR02790
nickel ABC transporter, permease subunit NikC; This family consists of the NikC family of ...
 41-268 3.74e-33

nickel ABC transporter, permease subunit NikC; This family consists of the NikC family of nickel ABC transporter permeases. Operons that contain this protein also contain a homologous permease subunit NikB. Nickel is used in cells as part of urease or certain hydrogenases or superoxide dismutases. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131837 [Multi-domain]  Cd Length: 258  Bit Score: 121.72  E-value: 3.74e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511278481   41 LIPPSKEHWFGTDDLGIDIFSEICYGAKSTIILSCSSALFAAVGGSIIGMVAGYFGGIFDEILLGIIDFFISVPDLLLMV 120
Cdd:TIGR02790  35 LLGPSMEYWLGTDHLGRCIFSRLIFGARVSLGSALLVLGLVLTIGLLIGGLAGYIGGRVDEAIMRVCDVFLSFPTIILSL 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511278481  121 VLGTFLGPSLKNIIFSIVLVSWIMPAKITRSQILRMKQENYIKIAKIYGAGFIHLFLWHFWKQFFSIIMMSVIKLMNRAI 200
Cdd:TIGR02790 115 AIVGILGPGLENVIIAIVLVHWAWYARMVRGMVVSLKQREFVLAARTSGASHWQIIRRHILPNILSPIIVLATLDIGHVI 194

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 511278481  201 LAEAALSYLGLG-DPLSKSWGMIITRAMDFPNIYLTEfwkwwLVYPVIFMVLMVLSIAIIGQKIEGKIG 268
Cdd:TIGR02790 195 LHIAGLSFLGLGiQPPTPEWGAMLSEAKQYIWTQPLL-----MIYPGLAILISVMAFNLLGDALRDHLG 258
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 70-234 1.60e-10

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 58.83  E-value: 1.60e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511278481  70 TIILSCSSALFAAVGGSIIGMVAGYFGGIFDEILLGIIDFFISVPDLLLMVVLGTFLGPSLK--------NIIFSIVLVS 141
Cdd:cd06261    4 TLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGwgilpglgLPALILALLL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511278481 142 WIMPAKITRSQILRMKQENYIKIAKIYGAGFIHLFLWHFWKQFFSIIMMSVIKLMNRAILAEAALSYLGLGDPLSKSWGM 221
Cdd:cd06261   84 IAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPGTGL 163

                        170
                 ....*....|...
gi 511278481 222 IITRAMDFPNIYL 234
Cdd:cd06261  164 LLIFAILFPGDLG 176
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 85-259 7.55e-07

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 48.45  E-value: 7.55e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511278481   85 GSIIGMVAG-YFGGIFDEILLGIIDFFISVPDLLLMVVLGTFLGPS----LKNIIFSIVLVSWIMPAKITRSQILRMKQE 159
Cdd:pfam00528   1 GIPLGIIAAlRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSilghGILPAIILALLGWAGYARLIRRAALRSLPS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511278481  160 NYIKIAKIYGAGFIHLFLWHFWKQFFSIIMMSVIKLMNRAILAEAALSYLGLGDPLSkSWGMIITRAMDFPNIYltefwk 239
Cdd:pfam00528  81 DLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLG-LLLIEAILGYDYPEIQ------ 153

                         170       180
                  ....*....|....*....|
gi 511278481  240 wwlvYPVIFMVLMVLSIAII 259
Cdd:pfam00528 154 ----GPVLAAALILLLLNLL 169
 
Name Accession Description Interval E-value
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 38-260 1.79e-63

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 200.34  E-value: 1.79e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511278481  38 GAALIPPSKEHWFGTDDLGIDIFSEICYGAKSTIILSCSSALFAAVGGSIIGMVAGYFGGIFDEILLGIIDFFISVPDLL 117
Cdd:COG1173   49 AARLQPPSAAHWLGTDQLGRDVLSRLLYGARISLLVGLLAVLIALVIGVLLGLLAGYFGGWVDAVLMRLVDVLLAFPSLL 128

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511278481 118 LMVVLGTFLGPSLKNIIFSIVLVSWIMPAKITRSQILRMKQENYIKIAKIYGAGFIHLFLWHFWKQFFSIIMMSVIKLMN 197
Cdd:COG1173  129 LAIALVAVLGPGLLNVILALGLTGWPGYARLVRAQVLSLREREYVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIA 208

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 511278481 198 RAILAEAALSYLGLG-DPLSKSWGMIITRAMDfpniYLTEFWkWWLVYPVIFMVLMVLSIAIIG 260
Cdd:COG1173  209 SAILAEAGLSFLGLGvQPPTPSWGTMLSEGRN----YLLTAP-WLALFPGLAIVLTVLAFNLLG 267
PRK09881 PRK09881
D,D-dipeptide ABC transporter permease;
39-245 2.12e-35

D,D-dipeptide ABC transporter permease;


Pssm-ID: 182131 [Multi-domain]  Cd Length: 296  Bit Score: 128.40  E-value: 2.12e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511278481  39 AALIPPSKEHWFGTDDLGIDIFSEICYGAKSTIILSCSSALFAAVGGSIIGMVAGYFGGIFDEILLGIIDFFISVPDLLL 118
Cdd:PRK09881  65 ARLLPPSAAHWFGTDEVGRDLFSRVLVGSQQSILAGLVVVAIAGMIGSLLGCLSGVLGGRADAIIMRIMDIMLSIPSLVL 144

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511278481 119 MVVLGTFLGPSLKNIIFSIVLVSWIMPAKITRSQILRMKQENYIKIAKIYGAGFIHLFLWHFWKQFFSIIMMSVIKLMNR 198
Cdd:PRK09881 145 TMALAAALGPSLFNAMLAIAIVRIPFYVRLARGQALVVRQYTYVQAAKTFGASRWHLISWHILRNSLPPLIVQASLDIGS 224

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 511278481 199 AILAEAALSYLGLG-DPLSKSWGMIITRAMDfpniYLTEFWkWWLVYP 245
Cdd:PRK09881 225 AILMAATLGFIGLGaQQPSAEWGAMVANGRN----YVLDQW-WYCAFP 267
nickel_nikC TIGR02790
nickel ABC transporter, permease subunit NikC; This family consists of the NikC family of ...
 41-268 3.74e-33

nickel ABC transporter, permease subunit NikC; This family consists of the NikC family of nickel ABC transporter permeases. Operons that contain this protein also contain a homologous permease subunit NikB. Nickel is used in cells as part of urease or certain hydrogenases or superoxide dismutases. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131837 [Multi-domain]  Cd Length: 258  Bit Score: 121.72  E-value: 3.74e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511278481   41 LIPPSKEHWFGTDDLGIDIFSEICYGAKSTIILSCSSALFAAVGGSIIGMVAGYFGGIFDEILLGIIDFFISVPDLLLMV 120
Cdd:TIGR02790  35 LLGPSMEYWLGTDHLGRCIFSRLIFGARVSLGSALLVLGLVLTIGLLIGGLAGYIGGRVDEAIMRVCDVFLSFPTIILSL 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511278481  121 VLGTFLGPSLKNIIFSIVLVSWIMPAKITRSQILRMKQENYIKIAKIYGAGFIHLFLWHFWKQFFSIIMMSVIKLMNRAI 200
Cdd:TIGR02790 115 AIVGILGPGLENVIIAIVLVHWAWYARMVRGMVVSLKQREFVLAARTSGASHWQIIRRHILPNILSPIIVLATLDIGHVI 194

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 511278481  201 LAEAALSYLGLG-DPLSKSWGMIITRAMDFPNIYLTEfwkwwLVYPVIFMVLMVLSIAIIGQKIEGKIG 268
Cdd:TIGR02790 195 LHIAGLSFLGLGiQPPTPEWGAMLSEAKQYIWTQPLL-----MIYPGLAILISVMAFNLLGDALRDHLG 258
nikC PRK10417
nickel transporter permease NikC; Provisional
 38-260 9.95e-29

nickel transporter permease NikC; Provisional


Pssm-ID: 236687 [Multi-domain]  Cd Length: 272  Bit Score: 110.14  E-value: 9.95e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511278481  38 GAALIPPSKEHWFGTDDLGIDIFSEICYGAKSTI--ILSCSSALFAAvgGSIIGMVAGYFGGIFDEILLGIIDFFISVPD 115
Cdd:PRK10417  37 PSRLLSPDAQHWLGTDHLGRDIFSRLMAGTRVSLgsVMACLLLVLAL--GLVIGGSAGLLGGRVDQATMRVADMFMTFPT 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511278481 116 LLLMVVLGTFLGPSLKNIIFSIVLVSWIMPAKITRSQILRMKQENYIKIAKIYGAGFIHLFLWHFWKQFFSIIMMSVIKL 195
Cdd:PRK10417 115 SILAFFMVGVLGTGLTNVIIAIALSHWAWYARMVRSLVISLRQREFVLAARLSGAGHVRVFIDHLLPAVIPQLLVLATLD 194

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 511278481 196 MNRAILAEAALSYLGLG-DPLSKSWGMIITRAMDFpniylteFWK--WWLVYPVIFMVLMVLSIAIIG 260
Cdd:PRK10417 195 IGHMMLHVAGLSFLGLGvTAPTAEWGVMINDARQY-------IWTqpLLMFWPGLALFISVMAFNLLG 255
PRK10913 PRK10913
dipeptide ABC transporter permease DppC;
39-260 1.28e-26

dipeptide ABC transporter permease DppC;


Pssm-ID: 182833 [Multi-domain]  Cd Length: 300  Bit Score: 105.25  E-value: 1.28e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511278481  39 AALIPP------SKEHWFGTDDLGIDIFSEICYGAKSTIILSCSSALFAAVGGSIIGMVAGYFGGIFDEILLGIIDFFIS 112
Cdd:PRK10913  64 ALLAPPvwqeggSWAHILGTDDVGRDVLSRLMYGARLSLLVGCLVVVLSLVMGVILGLIAGYFGGLVDNIIMRVVDIMLA 143

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511278481 113 VPDLLLMVVLGTFLGPSLKNIIFSIVLVSWIMPAKITRSQILRMKQENYIKIAKIYGAGFIHLFLWHFWKQFFSIIMMSV 192
Cdd:PRK10913 144 LPSLLLALVLVAIFGPSIVNAALALTFVALPHYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFINILPNCLAPLIVQA 223

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511278481 193 IKLMNRAILAEAALSYLGLG-DPLSKSWGMIITRAMDFPNIyltefwKWWLV-YPVIFMVLMVLSIAIIG 260
Cdd:PRK10913 224 SLGFSNAILDMAALGFLGMGaQPPTPEWGTMLSDVLQFAQS------AWWVVtFPGLAILLTVLAFNLMG 287
PRK15406 PRK15406
oligopeptide ABC transporter permease OppC; Provisional
 48-260 1.70e-25

oligopeptide ABC transporter permease OppC; Provisional


Pssm-ID: 185304 [Multi-domain]  Cd Length: 302  Bit Score: 102.22  E-value: 1.70e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511278481  48 HWFGTDDLGIDIFSEICYGAKSTIILSCSSALFAAVGGSIIGMVAGYFGGIFDEILLGIIDFFISVPDLLLMVVLGTFLG 127
Cdd:PRK15406  82 HYFGTDSSGRDLLVRVAIGGRISLMVGVAAALVAVVVGTLYGSLSGYLGGKVDSVMMRLLEILNSFPFMFFVILLVTFFG 161

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511278481 128 PSLKNIIFSIVLVSWIMPAKITRSQILRMKQENYIKIAKIYGAGFIHLFLWHFWKQFFSIIMMSVIKLMNRAILAEAALS 207
Cdd:PRK15406 162 QNILLIFVAIGMVSWLDMARIVRGQTLSLKRKEFIEAAQVGGVSTRGIVLRHIVPNVLGVVVVYASLLVPSMILFESFLS 241

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 511278481 208 YLGLG--DPLSkSWGMIITRAMDFpniylTEFWKWWLVYPVIFMVLMVLSIAIIG 260
Cdd:PRK15406 242 FLGLGtqEPLS-SWGALLSDGANS-----MEVSPWLLLFPAGFLVVTLFCFNFIG 290
PRK15082 PRK15082
glutathione ABC transporter permease GsiD; Provisional
 44-226 7.18e-24

glutathione ABC transporter permease GsiD; Provisional


Pssm-ID: 185040 [Multi-domain]  Cd Length: 301  Bit Score: 97.88  E-value: 7.18e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511278481  44 PSKEHWFGTDDLGIDIFSEICYGAKSTIILSCSSALFAAVGGSIIGMVAGYFGGIFDEILLGIIDFFISVPDLLLMVVLG 123
Cdd:PRK15082  76 PSLQHWFGVDSLGRDIFSRILVGARISLAAGFFSVAIGAAIGTVLGLLAGYYEGWWDRIIMRICDVLFAFPGILLAIAVV 155

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511278481 124 TFLGPSLKNIIFSIVLVSWIMPAKITRSQILRMKQENYIKIAKIYGAGFIHLFLWHFWKQFFSIIMMSVIKLMNRAILAE 203
Cdd:PRK15082 156 AILGSGMANVIIAVAIFSIPAFARLVRGNTLVLKQQTYIESARSIGASDWTILLRHILPGTVSSIVVYFTMRIGTSIITA 235

                        170       180
                 ....*....|....*....|....
gi 511278481 204 AALSYLGLG-DPLSKSWGMIITRA 226
Cdd:PRK15082 236 ASLSFLGLGaQPPTPEWGAMLNEA 259
YejE COG4239
ABC-type microcin C transport system, permease component YejE [Secondary metabolites ...
 43-260 7.44e-21

ABC-type microcin C transport system, permease component YejE [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443381 [Multi-domain]  Cd Length: 342  Bit Score: 90.21  E-value: 7.44e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511278481  43 PPSKEHWFGTDDLGIDIFSEICYGAKSTIILSCSSALFAAVGGSIIGMVAGYFGGIFDEILLGIIDFFISVPDLLLMVVL 122
Cdd:COG4239  116 PPSAENWLGTDDQGRDVLARLIYGFRISVLFGLALTVISSVIGVAAGAVQGYFGGRVDLLFQRFIEIWSSMPELYLLIIL 195

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511278481 123 GTFLGPSLKNIIFSIVLVSWIMPAKITRSQILRMKQENYIKIAKIYGAGFIHLFLWHfwkqffsII---MMSVIK----L 195
Cdd:COG4239  196 SSIFQPSFWLLLGILLLFGWMGLVGVVRAEFLRARNLEYVRAARALGVSDRRIMFRH-------ILpnaMVATLTflpfI 268

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 511278481 196 MNRAILAEAALSYLGLGDPL-SKSWGMIITRAMDfpNIYltefwKWWLVYPVIF-MVLMVLSIAIIG 260
Cdd:COG4239  269 LSGAITTLTSLDFLGFGLPPgSPSLGELLAQGKN--NLQ-----APWLGLSAFVvLALMLSLLVFIG 328
PRK15021 PRK15021
microcin C ABC transporter permease; Provisional
 43-263 1.32e-18

microcin C ABC transporter permease; Provisional


Pssm-ID: 184982 [Multi-domain]  Cd Length: 341  Bit Score: 83.88  E-value: 1.32e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511278481  43 PPSKEHWFGTDDLGIDIFSEICYGAKSTIILSCSSALFAAVGGSIIGMVAGYFGGIFDEILLGIIDFFISVPDLLLMVVL 122
Cdd:PRK15021 116 PPSRQNWLGTDANGGDVLARILYGTRISVLFGLMLTLCSSVMGVLAGALQGYYGGKVDLWGQRFIEVWSGMPTLFLIILL 195

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511278481 123 GTFLGPSLKNIIFSIVLVSWIMPAKITRSQILRMKQENYIKIAKIYGAGFIHLFLWHFWKQFFSIIMMSVIKLMNRAILA 202
Cdd:PRK15021 196 SSVVQPNFWWLLAITVLFGWMSLVGVVRAEFLRTRNFDYIRAAQALGVSDRSIILRHMLPNAMVATLTFLPFILCSSITT 275

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 511278481 203 EAALSYLGLGDPL-SKSWGMIITRAMDfpniyltEFWKWWLVYPVIFMVLMVLSIAI-IGQKI 263
Cdd:PRK15021 276 LTSLDFLGFGLPLgSPSLGELLLQGKN-------NLQAPWLGITAFLSVAILLSLLIfIGEAV 331
PRK15111 PRK15111
peptide ABC transporter permease SapC;
38-263 2.73e-18

peptide ABC transporter permease SapC;


Pssm-ID: 185066 [Multi-domain]  Cd Length: 296  Bit Score: 82.44  E-value: 2.73e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511278481  38 GAALIPPSKEHW------FGTDDLGIDIFSEICYGAKSTIILSCSSALFAAVGGSIIGMVAGYFGGIFDEILLGIIDFFI 111
Cdd:PRK15111  60 GYQLLPPSWSRYgevsffLGTDDLGRDVLSRLLSGAAPTVGGAFVVTLAATLCGLVLGVFAGATHGLRSAVLNHILDTLL 139

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511278481 112 SVPDLLLMVVLGTFLGPSLKNIIFSIVLVswIMPaKITRSQILRMKQE---NYIKIAKIYGAGFIHLFLWHFWKQFFSII 188
Cdd:PRK15111 140 SIPSLLLAIIVVAFAGPSLSHAMFAVWLA--LLP-RMVRSIYSAVHDElekEYVIAARLDGASTLNILWYAVLPNITAGL 216

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 511278481 189 MMSVIKLMNRAILAEAALSYLGLGDPL-SKSWGMIITRAMDFpnIYLTefwKWWLVYPVIFMVLMVLSIAIIGQKI 263
Cdd:PRK15111 217 VTEITRALSMAILDIAALGFLDLGAQLpSPEWGAMLGDSLEL--IYVA---PWTVMLPGAAIMLSVLLVNLLGDGI 287
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 70-234 1.60e-10

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 58.83  E-value: 1.60e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511278481  70 TIILSCSSALFAAVGGSIIGMVAGYFGGIFDEILLGIIDFFISVPDLLLMVVLGTFLGPSLK--------NIIFSIVLVS 141
Cdd:cd06261    4 TLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGwgilpglgLPALILALLL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511278481 142 WIMPAKITRSQILRMKQENYIKIAKIYGAGFIHLFLWHFWKQFFSIIMMSVIKLMNRAILAEAALSYLGLGDPLSKSWGM 221
Cdd:cd06261   84 IAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPGTGL 163

                        170
                 ....*....|...
gi 511278481 222 IITRAMDFPNIYL 234
Cdd:cd06261  164 LLIFAILFPGDLG 176
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 85-259 7.55e-07

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 48.45  E-value: 7.55e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511278481   85 GSIIGMVAG-YFGGIFDEILLGIIDFFISVPDLLLMVVLGTFLGPS----LKNIIFSIVLVSWIMPAKITRSQILRMKQE 159
Cdd:pfam00528   1 GIPLGIIAAlRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSilghGILPAIILALLGWAGYARLIRRAALRSLPS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511278481  160 NYIKIAKIYGAGFIHLFLWHFWKQFFSIIMMSVIKLMNRAILAEAALSYLGLGDPLSkSWGMIITRAMDFPNIYltefwk 239
Cdd:pfam00528  81 DLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLG-LLLIEAILGYDYPEIQ------ 153

                         170       180
                  ....*....|....*....|
gi 511278481  240 wwlvYPVIFMVLMVLSIAII 259
Cdd:pfam00528 154 ----GPVLAAALILLLLNLL 169
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 70-212 3.82e-06

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 47.37  E-value: 3.82e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511278481  70 TIILSCSSALFAAVGGSIIGMVAGYF-GGIFDEILLGIIDFFISVPD----LLLMVVLGTFLG---------------PS 129
Cdd:COG0601   98 TLELALLALLLALLIGIPLGILAALRrGSWLDRLITVLALLGISIPSfwlgLLLILLFAVKLGwlpvsgrvspwedflDA 177

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511278481 130 LKNII---FSIVLVSWIMPAKITRSQILRMKQENYIKIAKIYGAGFIHLFLWHFWK----QFFSIIMMSVIKLMNRAILA 202
Cdd:COG0601  178 LRHLIlpaLTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRnaliPVVTVLGLQLGGLLGGAVVV 257

                        170
                 ....*....|
gi 511278481 203 EAALSYLGLG 212
Cdd:COG0601  258 ETVFSWPGLG 267
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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