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Conserved domains on  [gi|506267548|ref|WP_015787323|]
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sodium:proton antiporter [Saccharomonospora viridis]

Protein Classification

sodium:proton antiporter( domain architecture ID 10002944)

sodium:proton antiporter is a transmembrane protein that plays a critical role in maintaining intracellular pH levels in bacteria and may contribute to salt tolerance in plants

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
MnhC COG1006
Multisubunit Na+/H+ antiporter, MnhC subunit [Inorganic ion transport and metabolism];
1-78 3.52e-20

Multisubunit Na+/H+ antiporter, MnhC subunit [Inorganic ion transport and metabolism];


:

Pssm-ID: 440630  Cd Length: 113  Bit Score: 79.00  E-value: 3.52e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506267548   1 MNLAIAGTAALLFGSGAYLLLQHELVRVTAGIVLISQSAVLMIIGSS-LFRGKAPLVPTDD---QVADPLPQALALTALV 76
Cdd:COG1006    1 MELLLALVIGVLFAIGVYLLLRRNLIKVIIGLSLLSNAVNLLLFAMGgLTGGAPPILGEGPpaaPYADPLPQALVLTAIV 80

                 ..
gi 506267548  77 IG 78
Cdd:COG1006   81 IG 82
 
Name Accession Description Interval E-value
MnhC COG1006
Multisubunit Na+/H+ antiporter, MnhC subunit [Inorganic ion transport and metabolism];
1-78 3.52e-20

Multisubunit Na+/H+ antiporter, MnhC subunit [Inorganic ion transport and metabolism];


Pssm-ID: 440630  Cd Length: 113  Bit Score: 79.00  E-value: 3.52e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506267548   1 MNLAIAGTAALLFGSGAYLLLQHELVRVTAGIVLISQSAVLMIIGSS-LFRGKAPLVPTDD---QVADPLPQALALTALV 76
Cdd:COG1006    1 MELLLALVIGVLFAIGVYLLLRRNLIKVIIGLSLLSNAVNLLLFAMGgLTGGAPPILGEGPpaaPYADPLPQALVLTAIV 80

                 ..
gi 506267548  77 IG 78
Cdd:COG1006   81 IG 82
PRK12659 PRK12659
Na+/H+ antiporter subunit C;
1-109 3.49e-14

Na+/H+ antiporter subunit C;


Pssm-ID: 183659  Cd Length: 117  Bit Score: 63.91  E-value: 3.49e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506267548   1 MNLAIAGTAALLFGSGAYLLLQHELVRVTAGIVLISQSAVLMI-IGSSLFRGKAPLVPTDDQ-----VADPLPQALALTA 74
Cdd:PRK12659   1 MEFLLAIVVGGLYAAGIYMMLRRSIVKLVIGLILLGNAANLLIfTVGRLTRGAPPLVPEGATapagpVADPLPQALILTA 80
                         90       100       110
                 ....*....|....*....|....*....|....*
gi 506267548  75 LVIGLATVALLLALMNRVTTVFRSARRNELITSET 109
Cdd:PRK12659  81 IVIGFGVQAFAIVLIKRAYQVVGTDDLDEMKTTDT 115
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
8-78 1.17e-04

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 38.31  E-value: 1.17e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 506267548    8 TAALLFGSGAY-LLLQHELVRVTAGIVLISQSAVLMIIGSSLFRgkaplvptddqvADPLPQALALTALVIG 78
Cdd:pfam00420   5 LSGLLFLIGLYgLLLRRNLLRVLLSLELMLNAVNLALVLFGRLT------------ADPLPQALILTAIVIA 64
 
Name Accession Description Interval E-value
MnhC COG1006
Multisubunit Na+/H+ antiporter, MnhC subunit [Inorganic ion transport and metabolism];
1-78 3.52e-20

Multisubunit Na+/H+ antiporter, MnhC subunit [Inorganic ion transport and metabolism];


Pssm-ID: 440630  Cd Length: 113  Bit Score: 79.00  E-value: 3.52e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506267548   1 MNLAIAGTAALLFGSGAYLLLQHELVRVTAGIVLISQSAVLMIIGSS-LFRGKAPLVPTDD---QVADPLPQALALTALV 76
Cdd:COG1006    1 MELLLALVIGVLFAIGVYLLLRRNLIKVIIGLSLLSNAVNLLLFAMGgLTGGAPPILGEGPpaaPYADPLPQALVLTAIV 80

                 ..
gi 506267548  77 IG 78
Cdd:COG1006   81 IG 82
PRK12659 PRK12659
Na+/H+ antiporter subunit C;
1-109 3.49e-14

Na+/H+ antiporter subunit C;


Pssm-ID: 183659  Cd Length: 117  Bit Score: 63.91  E-value: 3.49e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506267548   1 MNLAIAGTAALLFGSGAYLLLQHELVRVTAGIVLISQSAVLMI-IGSSLFRGKAPLVPTDDQ-----VADPLPQALALTA 74
Cdd:PRK12659   1 MEFLLAIVVGGLYAAGIYMMLRRSIVKLVIGLILLGNAANLLIfTVGRLTRGAPPLVPEGATapagpVADPLPQALILTA 80
                         90       100       110
                 ....*....|....*....|....*....|....*
gi 506267548  75 LVIGLATVALLLALMNRVTTVFRSARRNELITSET 109
Cdd:PRK12659  81 IVIGFGVQAFAIVLIKRAYQVVGTDDLDEMKTTDT 115
PRK12658 PRK12658
Na+/H+ antiporter subunit C;
1-78 4.80e-12

Na+/H+ antiporter subunit C;


Pssm-ID: 183658  Cd Length: 125  Bit Score: 58.54  E-value: 4.80e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506267548   1 MNLAIAGTAALLFGSGAYLLLQHELVRVTAGIVLISQSAVLMII-GSSLFRGKAPLVP-----TDDQVADPLPQALALTA 74
Cdd:PRK12658   1 MEALFAILVGVFFAAAIYLMLSRHIIRILFGLALLGNAVNLLIFtAGRLTREVPPLIPagadvLAEGAANPLPQALILTA 80

                 ....
gi 506267548  75 LVIG 78
Cdd:PRK12658  81 IVIG 84
PRK07375 PRK07375
Na+/H+ antiporter subunit C;
1-78 1.85e-11

Na+/H+ antiporter subunit C;


Pssm-ID: 236004  Cd Length: 112  Bit Score: 56.43  E-value: 1.85e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506267548   1 MNLAIAGTAALLFGSGAYLLLQHELVRVTAGIVLISQSAVLMIIGS-SLFRGKAPLVPTDD--QVADPLPQALALTALVI 77
Cdd:PRK07375   2 QLMIYALAIALLVIGLYGLIFKRNLLKKIIGLDVFQTGVNLFYIAIgYRSGGGVPILSPSGftTYADPLPQALVLTAIVI 81

                 .
gi 506267548  78 G 78
Cdd:PRK07375  82 G 82
PRK07946 PRK07946
putative monovalent cation/H+ antiporter subunit C; Reviewed
2-77 1.84e-10

putative monovalent cation/H+ antiporter subunit C; Reviewed


Pssm-ID: 236136  Cd Length: 163  Bit Score: 55.05  E-value: 1.84e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506267548   2 NLAIAGTAALLFGSGAYLLLQHELVRVTAGIVLISQSAVLMIIGSSLFRGKAPLV----PTDDQVADPLPQALALTALVI 77
Cdd:PRK07946   4 NLGLLVAIGVLTSAGVYLLLERSLTRMLLGLLLIGNGVNLLILTAGGPAGNPPILgrtsEYGETMADPLAQAMILTAIVI 83
PRK09094 PRK09094
putative monovalent cation/H+ antiporter subunit C; Reviewed
1-78 2.46e-10

putative monovalent cation/H+ antiporter subunit C; Reviewed


Pssm-ID: 236377  Cd Length: 114  Bit Score: 53.73  E-value: 2.46e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506267548   1 MNLAIAGTAALLFGSGAYLLLQHELVRVTAGIVLISQSAVLMIIGS-SLFRGKAPLV-----PTDDQVADPLPQALALTA 74
Cdd:PRK09094   1 MELVLALAIGVLTASGVWLLLRPRTFQVILGLSLLSYAVNLFIFAMgRLRVGAPPVLqpgvpVDLANYTDPLPQALVLTA 80

                 ....
gi 506267548  75 LVIG 78
Cdd:PRK09094  81 IVIG 84
PRK08600 PRK08600
putative monovalent cation/H+ antiporter subunit C; Reviewed
1-77 7.05e-10

putative monovalent cation/H+ antiporter subunit C; Reviewed


Pssm-ID: 181497  Cd Length: 113  Bit Score: 52.65  E-value: 7.05e-10
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 506267548   1 MNLAIAGTAALLFGSGAYLLLQHELVRVTAGIVLISQSAVLMIIG-SSLFRGKAPLVPTDD-QVADPLPQALALTALVI 77
Cdd:PRK08600   1 MEILMIIVIGILTAIAVYLILSKSLLRIIIGTTLLSHGANLLLLTmGGLKKGAVPILGEGVtSYVDPLPQALILTAIVI 79
PRK12660 PRK12660
putative monovalent cation/H+ antiporter subunit C; Reviewed
1-78 3.35e-08

putative monovalent cation/H+ antiporter subunit C; Reviewed


Pssm-ID: 183660  Cd Length: 114  Bit Score: 48.19  E-value: 3.35e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506267548   1 MNLAIAGTAALLFGSGAYLLLQHELVRVTAGIVLISQSAVLMIIGSSLFRGK--APLVPTDDQ-VADPLPQALALTALVI 77
Cdd:PRK12660   1 MNLILLLVIGFLVFIGTYMILSINLIRIVIGISIYTHAGNLIIMSMGGYGSSrsEPLITGGNQlFVDPLLQAIVLTAIVI 80

                 .
gi 506267548  78 G 78
Cdd:PRK12660  81 G 81
PRK12661 PRK12661
putative monovalent cation/H+ antiporter subunit C; Reviewed
2-78 2.81e-07

putative monovalent cation/H+ antiporter subunit C; Reviewed


Pssm-ID: 237162  Cd Length: 140  Bit Score: 46.30  E-value: 2.81e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506267548   2 NLAIAGTAALLFGSGAYLLLQHELVRVTAGIVLISQSAVLMIIGSSLFRGK----------------------------A 53
Cdd:PRK12661   3 NFFLSLTIALLFGIGTFLILRRDMIKVIIGLSIISHAVNLLIVSSGVFEGTkvpiiteqghegsgsgiiyndnltsgilA 82
                         90       100
                 ....*....|....*....|....*..
gi 506267548  54 PLVP--TDDQVADPLPQALALTALVIG 78
Cdd:PRK12661  83 PIVTngPETEFVDPLVQALVLTAIVIG 109
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
8-78 1.17e-04

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 38.31  E-value: 1.17e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 506267548    8 TAALLFGSGAY-LLLQHELVRVTAGIVLISQSAVLMIIGSSLFRgkaplvptddqvADPLPQALALTALVIG 78
Cdd:pfam00420   5 LSGLLFLIGLYgLLLRRNLLRVLLSLELMLNAVNLALVLFGRLT------------ADPLPQALILTAIVIA 64
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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