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Conserved domains on  [gi|506249650|ref|WP_015769425|]
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HPr family phosphocarrier protein [Leptotrichia buccalis]

Protein Classification

HPr family phosphocarrier protein( domain architecture ID 10448849)

HPr family phosphocarrier protein is part of a phosphoenolpyruvate-dependent phosphotransferase (PTS)-like system that catalyzes the phosphorylation of incoming substrates with their concomitant translocation across the cell membrane

CATH:  3.30.1340.10
Gene Ontology:  GO:0009401
PubMed:  12405346
SCOP:  4001693

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PTS-HPr pfam00381
PTS HPr component phosphorylation site;
4-81 1.35e-20

PTS HPr component phosphorylation site;


:

Pssm-ID: 459792 [Multi-domain]  Cd Length: 79  Bit Score: 83.59  E-value: 1.35e-20
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 506249650    4 KTIIFNYRYGIDIYFATEVMRKAREFESKIEIEYDGKKIKNKSPLMLSGFGIKMGSEITIYADGSDEEEALETVSNLL 81
Cdd:pfam00381   1 KTVTITNPLGLHARPAALLVQLASKFDSDITLEKGGKKVNAKSIMGLMSLGAKQGDEITISAEGEDEEEALEALAALL 78
 
Name Accession Description Interval E-value
PTS-HPr pfam00381
PTS HPr component phosphorylation site;
4-81 1.35e-20

PTS HPr component phosphorylation site;


Pssm-ID: 459792 [Multi-domain]  Cd Length: 79  Bit Score: 83.59  E-value: 1.35e-20
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 506249650    4 KTIIFNYRYGIDIYFATEVMRKAREFESKIEIEYDGKKIKNKSPLMLSGFGIKMGSEITIYADGSDEEEALETVSNLL 81
Cdd:pfam00381   1 KTVTITNPLGLHARPAALLVQLASKFDSDITLEKGGKKVNAKSIMGLMSLGAKQGDEITISAEGEDEEEALEALAALL 78
PtsH COG1925
HPr or related phosphotransfer protein [Signal transduction mechanisms, Carbohydrate transport ...
 1-81 1.19e-16

HPr or related phosphotransfer protein [Signal transduction mechanisms, Carbohydrate transport and metabolism];


Pssm-ID: 441528 [Multi-domain]  Cd Length: 88  Bit Score: 73.60  E-value: 1.19e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506249650   1 MVSKTIIFNYRYGIDIYFATEVMRKAREFESKIEIEYDGKKIKNKSPLMLSGFGIKMGSEITIYADGSDEEEALETVSNL 80
Cdd:COG1925    1 MLEREVTIVNKLGLHARPAAKLVQLASKFDSEITVEKGGKEVNAKSIMGLMSLGAKKGDEVTITAEGPDAEEALDALAAL 80


                 .
gi 506249650  81 L 81
Cdd:COG1925   81 I 81
PRK13780 PRK13780
phosphocarrier protein HPr; Provisional
 1-84 2.18e-14

phosphocarrier protein HPr; Provisional


Pssm-ID: 237503 [Multi-domain]  Cd Length: 88  Bit Score: 67.41  E-value: 2.18e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506249650   1 MVSKTIIFNYRYGIDIYFATEVMRKAREFESKIEIEYDGKKIKNKSPLMLSGFGIKMGSEITIYADGSDEEEALETVSNL 80
Cdd:PRK13780   1 MASKDFHITAETGIHARPATLLVQTASKFDSDITLEYNGKSVNLKSIMGVMSLGVGQGADITISAEGADAADAIAAIEET 80


                 ....
gi 506249650  81 LGVE 84
Cdd:PRK13780  81 MKKE 84
PTS_HPr_family TIGR01003
Phosphotransferase System HPr (HPr) Family; The HPr family are bacterial proteins (or domains ...
 1-81 2.07e-13

Phosphotransferase System HPr (HPr) Family; The HPr family are bacterial proteins (or domains of proteins) which function in phosphoryl transfer system (PTS) systems. They include energy-coupling components which catalyze sugar uptake via a group translocation mechanism. The functions of most of these proteins are not known, but they presumably function in PTS-related regulatory capacities. All seed members are stand-alone HPr proteins, although the model also recognizes HPr domains of PTS fusion proteins. This family includes the related NPr protein. [Signal transduction, PTS]


Pssm-ID: 273389 [Multi-domain]  Cd Length: 82  Bit Score: 64.59  E-value: 2.07e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506249650    1 MVSKTIIFNYRYGIDIYFATEVMRKAREFESKIEIEYDGKKIKNKSPLMLSGFGIKMGSEITIYADGSDEEEALETVSNL 80
Cdd:TIGR01003   1 MLSKEVTIINKVGLHARPAAILVKLASGFDSEITLTKNGKEVNAKSIMGIMMLGAGQGTEVTVSADGEDEAEALEALAKL 80


                  .
gi 506249650   81 L 81
Cdd:TIGR01003  81 F 81
 
Name Accession Description Interval E-value
PTS-HPr pfam00381
PTS HPr component phosphorylation site;
4-81 1.35e-20

PTS HPr component phosphorylation site;


Pssm-ID: 459792 [Multi-domain]  Cd Length: 79  Bit Score: 83.59  E-value: 1.35e-20
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 506249650    4 KTIIFNYRYGIDIYFATEVMRKAREFESKIEIEYDGKKIKNKSPLMLSGFGIKMGSEITIYADGSDEEEALETVSNLL 81
Cdd:pfam00381   1 KTVTITNPLGLHARPAALLVQLASKFDSDITLEKGGKKVNAKSIMGLMSLGAKQGDEITISAEGEDEEEALEALAALL 78
PtsH COG1925
HPr or related phosphotransfer protein [Signal transduction mechanisms, Carbohydrate transport ...
 1-81 1.19e-16

HPr or related phosphotransfer protein [Signal transduction mechanisms, Carbohydrate transport and metabolism];


Pssm-ID: 441528 [Multi-domain]  Cd Length: 88  Bit Score: 73.60  E-value: 1.19e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506249650   1 MVSKTIIFNYRYGIDIYFATEVMRKAREFESKIEIEYDGKKIKNKSPLMLSGFGIKMGSEITIYADGSDEEEALETVSNL 80
Cdd:COG1925    1 MLEREVTIVNKLGLHARPAAKLVQLASKFDSEITVEKGGKEVNAKSIMGLMSLGAKKGDEVTITAEGPDAEEALDALAAL 80


                 .
gi 506249650  81 L 81
Cdd:COG1925   81 I 81
PRK13780 PRK13780
phosphocarrier protein HPr; Provisional
 1-84 2.18e-14

phosphocarrier protein HPr; Provisional


Pssm-ID: 237503 [Multi-domain]  Cd Length: 88  Bit Score: 67.41  E-value: 2.18e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506249650   1 MVSKTIIFNYRYGIDIYFATEVMRKAREFESKIEIEYDGKKIKNKSPLMLSGFGIKMGSEITIYADGSDEEEALETVSNL 80
Cdd:PRK13780   1 MASKDFHITAETGIHARPATLLVQTASKFDSDITLEYNGKSVNLKSIMGVMSLGVGQGADITISAEGADAADAIAAIEET 80


                 ....
gi 506249650  81 LGVE 84
Cdd:PRK13780  81 MKKE 84
PTS_HPr_family TIGR01003
Phosphotransferase System HPr (HPr) Family; The HPr family are bacterial proteins (or domains ...
 1-81 2.07e-13

Phosphotransferase System HPr (HPr) Family; The HPr family are bacterial proteins (or domains of proteins) which function in phosphoryl transfer system (PTS) systems. They include energy-coupling components which catalyze sugar uptake via a group translocation mechanism. The functions of most of these proteins are not known, but they presumably function in PTS-related regulatory capacities. All seed members are stand-alone HPr proteins, although the model also recognizes HPr domains of PTS fusion proteins. This family includes the related NPr protein. [Signal transduction, PTS]


Pssm-ID: 273389 [Multi-domain]  Cd Length: 82  Bit Score: 64.59  E-value: 2.07e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506249650    1 MVSKTIIFNYRYGIDIYFATEVMRKAREFESKIEIEYDGKKIKNKSPLMLSGFGIKMGSEITIYADGSDEEEALETVSNL 80
Cdd:TIGR01003   1 MLSKEVTIINKVGLHARPAAILVKLASGFDSEITLTKNGKEVNAKSIMGIMMLGAGQGTEVTVSADGEDEAEALEALAKL 80


                  .
gi 506249650   81 L 81
Cdd:TIGR01003  81 F 81
PRK13782 PRK13782
HPr family phosphocarrier protein;
1-79 6.64e-12

HPr family phosphocarrier protein;


Pssm-ID: 172320 [Multi-domain]  Cd Length: 82  Bit Score: 60.18  E-value: 6.64e-12
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 506249650   1 MVSKTIIFNYRYGIDIYFATEVMRKAREFESKIEIEYDGKKIKNKSPLMLSGFGIKMGSEITIYADGSDEEEALETVSN 79
Cdd:PRK13782   1 MVQKRVEVSLKTGLQARPAALFVQEANRFHADIFIEKDGKKVNAKSIMGLMSLAIGTGSMITIITEGSDEEEALEALAA 79
PRK10850 PRK10850
phosphocarrier protein Hpr;
19-82 1.82e-07

phosphocarrier protein Hpr;


Pssm-ID: 182777 [Multi-domain]  Cd Length: 85  Bit Score: 48.20  E-value: 1.82e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 506249650  19 ATEVMRKAREFESKIEIEYDGKKIKNKSPLMLSGFGIKMGSEITIYADGSDEEEALETVSNLLG 82
Cdd:PRK10850  19 AAQFVKEAKGFTSEITVTSNGKSASAKSLFKLQTLGLTQGTVVTISAEGEDEQKAVEHLVKLMA 82
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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