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Conserved domains on  [gi|505913812|ref|WP_015714674|]
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MULTISPECIES: proline dehydrogenase family protein [Bacillus]

Protein Classification

bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase; bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase; proline dehydrogenase family protein; proline dehydrogenase family protein( domain architecture ID 11423475)

bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase catalyzes the two-step oxidation of proline to glutamate; bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase catalyzes the two-step oxidation of proline to glutamate; proline dehydrogenase family protein similar to Pectobacterium carotovorum carbapenem antibiotics biosynthesis protein CarD; proline dehydrogenase family protein similar to Pectobacterium carotovorum carbapenem antibiotics biosynthesis protein CarD; proline dehydrogenase family protein similar to Pectobacterium carotovorum carbapenem antibiotics biosynthesis protein CarD; proline dehydrogenase family protein similar to human mitochondrial proline dehydrogenase 1 that converts proline to delta-1-pyrroline-5-carboxylate; proline dehydrogenase family protein similar to Pectobacterium carotovorum carbapenem antibiotics biosynthesis protein CarD; proline dehydrogenase family protein similar to human mitochondrial proline dehydrogenase 1 that converts proline to delta-1-pyrroline-5-carboxylate; proline dehydrogenase family protein similar to human mitochondrial proline dehydrogenase 1 that converts proline to delta-1-pyrroline-5-carboxylate

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PutA super family cl33919
Proline dehydrogenase [Amino acid transport and metabolism]; Proline dehydrogenase is part of ...
 24-294 1.15e-79

Proline dehydrogenase [Amino acid transport and metabolism]; Proline dehydrogenase is part of the Pathway/BioSystem: Proline degradation


The actual alignment was detected with superfamily member COG0506:

Pssm-ID: 440272 [Multi-domain]  Cd Length: 975  Bit Score: 259.98  E-value: 1.15e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505913812  24 TRLGARRFVAGDTIESAVKTVKRLNRSGLCATIDYLGEYAASEKEANQVAEECKKAIQAIAEHQLD-SELSLKLTSIGLD 102
Cdd:COG0506  109 MRRMARRFVAGETIEEALKAARKLRAKGYRVSLDLLGEAVLTEAEAERYLDAYLEALEAIGAAGVDrPGVSVKLSALGPR 188

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505913812 103 LS-------EELALTHLRAILSVAKQYDVAVTIDMEDYSHYEQTLSIYRQCKQE-----FEKLGTVIQAYLYRAAEDIR- 169
Cdd:COG0506  189 YSpaqrervVEELLERLRPLARAAREAGIFVTIDMEEYDRLDLTLDVFERLLADpelagWPGVGIVLQAYLKRAEADLDr 268

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505913812 170 -----KMRDLKPNLRLVKGAYKESPAV----------AFPDKRGTDLHFQSLIKLQLLSGN--YTAVATHDDDIIAFTKQ 232
Cdd:COG0506  269 laalaRRGGRRIRVRLVKGAYWDPEIVraqvhgwpypVFTRKADTDANYLRCARKLLEAGDaiYPQFATHNARTIAAALA 348

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 505913812 233 LVTEHQIPASQFEFQMLYGIRPERQKELAKE-GYRMRVYVPYG----TDwfSYFMRRIAERPANAAF 294
Cdd:COG0506  349 LAGERGRPPDRFEFQMLYGMGEDLQRALAAVdGGRLLLYCPVVapvgGD--AALAYLLRRLLENNSF 413
 
Name Accession Description Interval E-value
PutA COG0506
Proline dehydrogenase [Amino acid transport and metabolism]; Proline dehydrogenase is part of ...
 24-294 1.15e-79

Proline dehydrogenase [Amino acid transport and metabolism]; Proline dehydrogenase is part of the Pathway/BioSystem: Proline degradation


Pssm-ID: 440272 [Multi-domain]  Cd Length: 975  Bit Score: 259.98  E-value: 1.15e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505913812  24 TRLGARRFVAGDTIESAVKTVKRLNRSGLCATIDYLGEYAASEKEANQVAEECKKAIQAIAEHQLD-SELSLKLTSIGLD 102
Cdd:COG0506  109 MRRMARRFVAGETIEEALKAARKLRAKGYRVSLDLLGEAVLTEAEAERYLDAYLEALEAIGAAGVDrPGVSVKLSALGPR 188

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505913812 103 LS-------EELALTHLRAILSVAKQYDVAVTIDMEDYSHYEQTLSIYRQCKQE-----FEKLGTVIQAYLYRAAEDIR- 169
Cdd:COG0506  189 YSpaqrervVEELLERLRPLARAAREAGIFVTIDMEEYDRLDLTLDVFERLLADpelagWPGVGIVLQAYLKRAEADLDr 268

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505913812 170 -----KMRDLKPNLRLVKGAYKESPAV----------AFPDKRGTDLHFQSLIKLQLLSGN--YTAVATHDDDIIAFTKQ 232
Cdd:COG0506  269 laalaRRGGRRIRVRLVKGAYWDPEIVraqvhgwpypVFTRKADTDANYLRCARKLLEAGDaiYPQFATHNARTIAAALA 348

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 505913812 233 LVTEHQIPASQFEFQMLYGIRPERQKELAKE-GYRMRVYVPYG----TDwfSYFMRRIAERPANAAF 294
Cdd:COG0506  349 LAGERGRPPDRFEFQMLYGMGEDLQRALAAVdGGRLLLYCPVVapvgGD--AALAYLLRRLLENNSF 413
Pro_dh pfam01619
Proline dehydrogenase;
40-295 1.57e-47

Proline dehydrogenase;


Pssm-ID: 426348 [Multi-domain]  Cd Length: 296  Bit Score: 161.12  E-value: 1.57e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505913812   40 AVKTVKRLNRSGLCATIDYLGEYAASEKEANQVAEECKKAIQAIAEHQLDSE------LSLKLTSIG--LDLSE-----E 106
Cdd:pfam01619   1 ALKTIEKLRKQGYRFSLDMLGEAALTEADADRYLDAYLRAIDALGKAAGPWPlgprpgISVKLSALHprYEPLErervmA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505913812  107 LALTHLRAILSVAKQYDVAVTIDMEDYSHYEQTLSIYRQ-----CKQEFEKLGTVIQAYLYRAAEDIRKMRDL------K 175
Cdd:pfam01619  81 ELLERLRPLCRLAKELGVRLNIDAEEADRLDLTLDLFERllaepELRGWNGVGITLQAYLKDALAVLDWLLELarrrgrP 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505913812  176 PNLRLVKGAYKES-PAVA---------FPDKRGTDLHFQSLIKLqLLSGN---YTAVATHDDDIIAFTKQLVTEHQIPAS 242
Cdd:pfam01619 161 LGVRLVKGAYWDSeIKRAqqggwpypvFTRKEATDANYEACARF-LLENHdriYPQFATHNARSVAAALALAEELGIPPR 239

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 505913812  243 QFEFQMLYGIRPERQKELAKEGYRMRVYVPYGT--DWFSYFMRRIAERPANAAFV 295
Cdd:pfam01619 240 RFEFQQLYGMGDNLSFALVAAGYRVRKYAPVGPheELLAYLVRRLLENTANSSFV 294
PRK11904 PRK11904
bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase PutA;
31-295 1.54e-21

bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase PutA;


Pssm-ID: 237017 [Multi-domain]  Cd Length: 1038  Bit Score: 94.88  E-value: 1.54e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505913812   31 FVAGDTIESAVKTVKRLNRSGLCATIDYLGEYAASEKEANQVAEECKKAIQAIAEHQLDSEL------SLKLTSigLD-- 102
Cdd:PRK11904  180 FVLGRTIEEALKRARSARNKGYRYSFDMLGEAALTAADAERYFKAYARAIEAIGRAAGGADLparpgiSIKLSA--LHpr 257

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505913812  103 ---LSEELALTHL----RAILSVAKQYDVAVTIDMEDYSHYEQTLSIYRQCKQE-----FEKLGTVIQAYLYRAA----- 165
Cdd:PRK11904  258 yeaAQRERVLAELvprvLELARLAKEANIGLTIDAEEADRLELSLDLFEALFRDpslkgWGGFGLAVQAYQKRALpvldw 337

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505913812  166 -EDIRKMRDLKPNLRLVKGAY-----KESPAVAFPD------KRGTDLHFQSLIKlQLLS--GN-YTAVATHDDDIIAFT 230
Cdd:PRK11904  338 lADLARRQGRRIPVRLVKGAYwdseiKRAQELGLPGypvftrKAATDVSYLACAR-KLLSarGAiYPQFATHNAHTVAAI 416

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 505913812  231 KQLVTEhqipaSQFEFQMLYGIRPERQKELAKE-GYRMRVYVPYGT--DWFSYFMRRIAERPANAAFV 295
Cdd:PRK11904  417 LEMAGH-----RGFEFQRLHGMGEALYDALLDApGIPCRIYAPVGShkDLLPYLVRRLLENGANSSFV 479
 
Name Accession Description Interval E-value
PutA COG0506
Proline dehydrogenase [Amino acid transport and metabolism]; Proline dehydrogenase is part of ...
 24-294 1.15e-79

Proline dehydrogenase [Amino acid transport and metabolism]; Proline dehydrogenase is part of the Pathway/BioSystem: Proline degradation


Pssm-ID: 440272 [Multi-domain]  Cd Length: 975  Bit Score: 259.98  E-value: 1.15e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505913812  24 TRLGARRFVAGDTIESAVKTVKRLNRSGLCATIDYLGEYAASEKEANQVAEECKKAIQAIAEHQLD-SELSLKLTSIGLD 102
Cdd:COG0506  109 MRRMARRFVAGETIEEALKAARKLRAKGYRVSLDLLGEAVLTEAEAERYLDAYLEALEAIGAAGVDrPGVSVKLSALGPR 188

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505913812 103 LS-------EELALTHLRAILSVAKQYDVAVTIDMEDYSHYEQTLSIYRQCKQE-----FEKLGTVIQAYLYRAAEDIR- 169
Cdd:COG0506  189 YSpaqrervVEELLERLRPLARAAREAGIFVTIDMEEYDRLDLTLDVFERLLADpelagWPGVGIVLQAYLKRAEADLDr 268

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505913812 170 -----KMRDLKPNLRLVKGAYKESPAV----------AFPDKRGTDLHFQSLIKLQLLSGN--YTAVATHDDDIIAFTKQ 232
Cdd:COG0506  269 laalaRRGGRRIRVRLVKGAYWDPEIVraqvhgwpypVFTRKADTDANYLRCARKLLEAGDaiYPQFATHNARTIAAALA 348

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 505913812 233 LVTEHQIPASQFEFQMLYGIRPERQKELAKE-GYRMRVYVPYG----TDwfSYFMRRIAERPANAAF 294
Cdd:COG0506  349 LAGERGRPPDRFEFQMLYGMGEDLQRALAAVdGGRLLLYCPVVapvgGD--AALAYLLRRLLENNSF 413
Pro_dh pfam01619
Proline dehydrogenase;
40-295 1.57e-47

Proline dehydrogenase;


Pssm-ID: 426348 [Multi-domain]  Cd Length: 296  Bit Score: 161.12  E-value: 1.57e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505913812   40 AVKTVKRLNRSGLCATIDYLGEYAASEKEANQVAEECKKAIQAIAEHQLDSE------LSLKLTSIG--LDLSE-----E 106
Cdd:pfam01619   1 ALKTIEKLRKQGYRFSLDMLGEAALTEADADRYLDAYLRAIDALGKAAGPWPlgprpgISVKLSALHprYEPLErervmA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505913812  107 LALTHLRAILSVAKQYDVAVTIDMEDYSHYEQTLSIYRQ-----CKQEFEKLGTVIQAYLYRAAEDIRKMRDL------K 175
Cdd:pfam01619  81 ELLERLRPLCRLAKELGVRLNIDAEEADRLDLTLDLFERllaepELRGWNGVGITLQAYLKDALAVLDWLLELarrrgrP 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505913812  176 PNLRLVKGAYKES-PAVA---------FPDKRGTDLHFQSLIKLqLLSGN---YTAVATHDDDIIAFTKQLVTEHQIPAS 242
Cdd:pfam01619 161 LGVRLVKGAYWDSeIKRAqqggwpypvFTRKEATDANYEACARF-LLENHdriYPQFATHNARSVAAALALAEELGIPPR 239

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 505913812  243 QFEFQMLYGIRPERQKELAKEGYRMRVYVPYGT--DWFSYFMRRIAERPANAAFV 295
Cdd:pfam01619 240 RFEFQQLYGMGDNLSFALVAAGYRVRKYAPVGPheELLAYLVRRLLENTANSSFV 294
PRK11904 PRK11904
bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase PutA;
31-295 1.54e-21

bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase PutA;


Pssm-ID: 237017 [Multi-domain]  Cd Length: 1038  Bit Score: 94.88  E-value: 1.54e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505913812   31 FVAGDTIESAVKTVKRLNRSGLCATIDYLGEYAASEKEANQVAEECKKAIQAIAEHQLDSEL------SLKLTSigLD-- 102
Cdd:PRK11904  180 FVLGRTIEEALKRARSARNKGYRYSFDMLGEAALTAADAERYFKAYARAIEAIGRAAGGADLparpgiSIKLSA--LHpr 257

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505913812  103 ---LSEELALTHL----RAILSVAKQYDVAVTIDMEDYSHYEQTLSIYRQCKQE-----FEKLGTVIQAYLYRAA----- 165
Cdd:PRK11904  258 yeaAQRERVLAELvprvLELARLAKEANIGLTIDAEEADRLELSLDLFEALFRDpslkgWGGFGLAVQAYQKRALpvldw 337

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505913812  166 -EDIRKMRDLKPNLRLVKGAY-----KESPAVAFPD------KRGTDLHFQSLIKlQLLS--GN-YTAVATHDDDIIAFT 230
Cdd:PRK11904  338 lADLARRQGRRIPVRLVKGAYwdseiKRAQELGLPGypvftrKAATDVSYLACAR-KLLSarGAiYPQFATHNAHTVAAI 416

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 505913812  231 KQLVTEhqipaSQFEFQMLYGIRPERQKELAKE-GYRMRVYVPYGT--DWFSYFMRRIAERPANAAFV 295
Cdd:PRK11904  417 LEMAGH-----RGFEFQRLHGMGEALYDALLDApGIPCRIYAPVGShkDLLPYLVRRLLENGANSSFV 479
PRK11905 PRK11905
bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed
 25-295 1.63e-15

bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed


Pssm-ID: 237018 [Multi-domain]  Cd Length: 1208  Bit Score: 76.83  E-value: 1.63e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505913812   25 RLGARRFVAGDTIESAVKTVKRLNRSGLCATIDYLGEYAASEKEANQVAEECKKAIQAIAEHQLDSEL------SLKLTS 98
Cdd:PRK11905  173 RMMGEQFVTGETIEEALKRARELEARGYRYSYDMLGEAARTAADAERYYRDYERAIHAIGKAATGRGVydgpgiSVKLSA 252

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505913812   99 IGLDLSE--------ELaLTHLRAILSVAKQYDVAVTIDMEDYSHYEQTLS-IYRQCKQE----FEKLGTVIQAYLYRAA 165
Cdd:PRK11905  253 LHPRYERaqrervmaEL-LPRLKALALLAKAYDIGLNIDAEEADRLELSLDlLEALCSDPdlagWNGIGFVVQAYQKRCP 331

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505913812  166 EDIRKMRDL------KPNLRLVKGAY-----KESPAVAFPD------KRGTDLHFQSLIKlQLLSGN---YTAVATHDdd 225
Cdd:PRK11905  332 FVIDYLIDLarrsgrRLMVRLVKGAYwdaeiKRAQVDGLEGfpvftrKVHTDVSYIACAR-KLLAARdviYPQFATHN-- 408

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 505913812  226 iiAFTKQLVTEHQIPASQFEFQMLYGI-RP--ERQKELAKEGYRMRVYVPYGT--DWFSYFMRRIAERPANAAFV 295
Cdd:PRK11905  409 --AQTLAAIYELAGGKGDFEFQCLHGMgEPlyDQVVGKEKLGRPCRIYAPVGTheTLLAYLVRRLLENGANSSFV 481
putA PRK11809
trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate ...
 25-295 4.85e-13

trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed


Pssm-ID: 236989 [Multi-domain]  Cd Length: 1318  Bit Score: 69.62  E-value: 4.85e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505913812   25 RLGARRFVAGDTIESAVKTVKRLNRSGLCATIDYLGEYAASEKEANQVAEECKKAIQAIAEHQLDSE------LSLKLTS 98
Cdd:PRK11809  253 RLMGEQFVTGETIAEALANARKLEEKGFRYSYDMLGEAALTEADAQAYLASYEQAIHAIGKASNGRGiyegpgISIKLSA 332

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505913812   99 IGLDLS--------EELaLTHLRAILSVAKQYDVAVTIDMEDYSHYEQTLSIY-RQCkqeFEK-------LGTVIQAYLY 162
Cdd:PRK11809  333 LHPRYSraqydrvmEEL-YPRLKSLTLLARQYDIGINIDAEEADRLEISLDLLeKLC---FEPelagwngIGFVIQAYQK 408

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505913812  163 RAAEDIRKMRDLKPN------LRLVKGAYKES-------------PavAFPDKRGTDLHFQSLIKlQLLSGN---YTAVA 220
Cdd:PRK11809  409 RCPFVIDYLIDLARRsrrrlmIRLVKGAYWDSeikraqvdglegyP--VYTRKVYTDVSYLACAR-KLLAVPnliYPQFA 485

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505913812  221 THDDDIIAFTKQLVTEHQIPAsQFEFQMLYG---------IRPERQKELAKEgyrMRVYVPYGT--DWFSYFMRRIAERP 289
Cdd:PRK11809  486 THNAHTLAAIYHLAGQNYYPG-QYEFQCLHGmgeplyeqvVGKVADGKLNRP---CRIYAPVGTheTLLAYLVRRLLENG 561


                  ....*.
gi 505913812  290 ANAAFV 295
Cdd:PRK11809  562 ANTSFV 567
PLN02681 PLN02681
proline dehydrogenase
 29-288 1.12e-11

proline dehydrogenase


Pssm-ID: 215366 [Multi-domain]  Cd Length: 455  Bit Score: 64.72  E-value: 1.12e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505913812  29 RRFVAGDTIESAVKTVKRLNRSGLCATIDYLGEYAASEKEANQVAEECKKAIQ-----------------AIAEHQL--- 88
Cdd:PLN02681  86 SHFCAGEDAEEAARTVRRLWELGLGGILDYAAEDAGDNAACDRNLEKFLAAIRaaatlppssssaavkitALCPPSLler 165

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505913812  89 ------------DSELSLKLTSIGLDLSE---------------------ELALTHLRAILSVAKQYDVAVTIDMED--- 132
Cdd:PLN02681 166 vsdllrwqdrdpNGKLPWKQWSFPLFADSsplyhatsepepltaeeerllELAHERLQKLCERAAQLGVPLLIDAEYtsl 245

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505913812 133 ---YSHYEQTLSIYRQCKQEFEKLGTVIQAYLY----RAAEDIRKMRDLKPNL--RLVKGAYKESPAvafpdKRGTDLHF 203
Cdd:PLN02681 246 qpaIDYITYDLAREFNKGKDRPIVYGTYQAYLKdareRLRLDLERSEREGVPLgaKLVRGAYLSLER-----RLAASLGV 320

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505913812 204 QSLIK-----------------LQLLSGNYTAV--ATHDDDIIAFTKQLVTEHQIPA--SQFEFQMLYGIRPERQKELAK 262
Cdd:PLN02681 321 PSPVHdtiqdthacynrcaeflLEKASNGDGEVmlATHNVESGELAAAKMNELGLHKgdPRVQFAQLLGMSDNLSFGLGN 400

                        330       340
                 ....*....|....*....|....*...
gi 505913812 263 EGYRMRVYVPYGT--DWFSYFMRRIAER 288
Cdd:PLN02681 401 AGFRVSKYLPYGPveEVIPYLLRRAEEN 428
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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