NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|500108776|ref|WP_011784781|]
View 

MULTISPECIES: phosphonate ABC transporter, permease protein PhnE [Proteobacteria]

Protein Classification

PhnE/PtxC family ABC transporter permease( domain architecture ID 11466536)

PhnE/PtxC family ABC transporter permease is the transmembrane subunit found in a periplasmic binding protein (PBP)-dependent ABC transport system, which may be involved in the transport of phosphonate, phosphate, or phosphite ions

Gene Ontology:  GO:0043190|GO:0140359|GO:0042626|GO:0016020
PubMed:  25750732|24638992|18535149|17723295
TCDB:  3.A.1

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
PhnE COG3639
ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport ...
 35-275 6.43e-108

ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport and metabolism];


:

Pssm-ID: 442856 [Multi-domain]  Cd Length: 244  Bit Score: 312.40  E-value: 6.43e-108
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500108776  35 LLVLLIIFVASWYVGLLNFNTLANGVPAIGTLIGESLPPDFTNVASWVSPLIDTLAMSIAGTAIAVTLSVPLAFLAARNT 114
Cdd:COG3639    3 LLALLALLVWSLWGLEFDLGRLIDGLPNLADFLSRFFPPDWSYLPDLLSALLETLAIALLGTLLGAVLALPLAFLAARNL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500108776 115 SPHPVVFQVTRTLLNGLRSVPELIMGIIFVAAVGFGALPGVLALGLHSIGMVGKFFAEAIEHVDEAPVEAADAAGATRLQ 194
Cdd:COG3639   83 APNPWVRLLARRLLNVLRAIPELVWALIFVAAVGLGPFAGVLALAIHTIGFLGKLFAEAIEEIDPGPVEALRATGASRLQ 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500108776 195 VLYHAVLPQALPQFADVSIYRWEYNFRASTVMGMVGAGGIGFELMGSLRIMQYQEVSAILIVILLMVTVVDSLSGRLRKK 274
Cdd:COG3639  163 VIRYGVLPQVLPQFLSYTLYRFEINIRAATVLGLVGAGGIGLLLNEAIRLFQYDEVAAILLVILVLVLLIDLLSARLRRR 242


                 .
gi 500108776 275 F 275
Cdd:COG3639  243 L 243
 
Name Accession Description Interval E-value
PhnE COG3639
ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport ...
 35-275 6.43e-108

ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 442856 [Multi-domain]  Cd Length: 244  Bit Score: 312.40  E-value: 6.43e-108
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500108776  35 LLVLLIIFVASWYVGLLNFNTLANGVPAIGTLIGESLPPDFTNVASWVSPLIDTLAMSIAGTAIAVTLSVPLAFLAARNT 114
Cdd:COG3639    3 LLALLALLVWSLWGLEFDLGRLIDGLPNLADFLSRFFPPDWSYLPDLLSALLETLAIALLGTLLGAVLALPLAFLAARNL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500108776 115 SPHPVVFQVTRTLLNGLRSVPELIMGIIFVAAVGFGALPGVLALGLHSIGMVGKFFAEAIEHVDEAPVEAADAAGATRLQ 194
Cdd:COG3639   83 APNPWVRLLARRLLNVLRAIPELVWALIFVAAVGLGPFAGVLALAIHTIGFLGKLFAEAIEEIDPGPVEALRATGASRLQ 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500108776 195 VLYHAVLPQALPQFADVSIYRWEYNFRASTVMGMVGAGGIGFELMGSLRIMQYQEVSAILIVILLMVTVVDSLSGRLRKK 274
Cdd:COG3639  163 VIRYGVLPQVLPQFLSYTLYRFEINIRAATVLGLVGAGGIGLLLNEAIRLFQYDEVAAILLVILVLVLLIDLLSARLRRR 242


                 .
gi 500108776 275 F 275
Cdd:COG3639  243 L 243
PhnE TIGR01097
phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound ...
 26-275 6.85e-103

phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions]


Pssm-ID: 273441 [Multi-domain]  Cd Length: 250  Bit Score: 299.84  E-value: 6.85e-103
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500108776   26 GWRKKLGQSLLVLLIIFVASWYVGLLNFNTLANGVPAIGTLIGESLPPDFTNVASWVSPLIDTLAMSIAGTAIAVTLSVP 105
Cdd:TIGR01097   1 RRRLIRIWLLALLVALYVWAFALLGFDLARLLAGPGQMADLLGRMFPPDWSYLPRILKALLETLAMAILGTVLAAVLAVP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500108776  106 LAFLAARNTSPHPVVFQVTRTLLNGLRSVPELIMGIIFVAAVGFGALPGVLALGLHSIGMVGKFFAEAIEHVDEAPVEAA 185
Cdd:TIGR01097  81 LALLAARNITPSPWLYGLARLLLNFLRAIPELVWALIFVAAVGLGPFAGVLALAFHTVGFLGKLFAEAIEEVDPGPVEAL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500108776  186 DAAGATRLQVLYHAVLPQALPQFADVSIYRWEYNFRASTVMGMVGAGGIGFELMGSLRIMQYQEVSAILIVILLMVTVVD 265
Cdd:TIGR01097 161 RATGASKLQVIRYGVLPQVLPQFLSYTLYRFEINVRAAAVLGLVGAGGIGLELDTAIGLFDYDEVSAIILVILVVVVIID 240

                         250
                  ....*....|
gi 500108776  266 SLSGRLRKKF 275
Cdd:TIGR01097 241 LISARLRRRL 250
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 85-264 6.01e-15

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 71.16  E-value: 6.01e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500108776  85 LIDTLAMSIAGTAIAVTLSVPLAFLAARNTSPhpvVFQVTRTLLNGLRSVPELIMGIIFVAAVG---------FGALPGV 155
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGK---LDRLLRRIIDLLLSLPSLVLGLLLVLLFGvllgwgilpGLGLPAL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500108776 156 LALGLHSIGMVGKFFAEAIEHVDEAPVEAADAAGATRLQVLYHAVLPQALPQFADVSIYRWEYNFRASTVMGMVGAG--- 232
Cdd:cd06261   78 ILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGeap 157

                        170       180       190
                 ....*....|....*....|....*....|..
gi 500108776 233 GIGFELMGSLRIMQYQEVSAILIVILLMVTVV 264
Cdd:cd06261  158 GPGTGLLLIFAILFPGDLGVAAAVALILLLLS 189
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 103-276 1.11e-13

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 67.71  E-value: 1.11e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500108776  103 SVPLAFLAARNtsPHPVVFQVTRTLLNGLRSVPELIMGIIFVAA-----VGFGALPGVLALGLHSIGMVGKFFAEAIEHV 177
Cdd:pfam00528   1 GIPLGIIAALR--RGRRLDRLLRPLIDLLQALPSFVLAILLVVIailsiLGHGILPAIILALLGWAGYARLIRRAALRSL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500108776  178 DEAPVEAADAAGATRLQVLYHAVLPQALPQFADVSIYRWEYNFRASTVMGMVGAG-GIGFELMGSLRIMQYQE----VSA 252
Cdd:pfam00528  79 PSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWpGLGLLLIEAILGYDYPEiqgpVLA 158

                         170       180
                  ....*....|....*....|....
gi 500108776  253 ILIVILLMVTVVDSLSGRLRKKFK 276
Cdd:pfam00528 159 AALILLLLNLLVDILQRLLDPRVR 182
PRK10782 PRK10782
D-methionine ABC transporter permease MetI;
117-235 1.62e-03

D-methionine ABC transporter permease MetI;


Pssm-ID: 182726  Cd Length: 217  Bit Score: 38.95  E-value: 1.62e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500108776 117 HPVVFQVTRTLLNGLRSVPELIMGII------FVAAVGFGALPGVLALGLHSIGMVGKFFAEAIEHVDEAPVEAADAAGA 190
Cdd:PRK10782  49 NAKLYRTLSALVNIFRSIPFIILLVWmipftrVIVGTSIGLQAAIVPLTVGAAPFIARMVENALLEIPTGLIEASRAMGA 128

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 500108776 191 TRLQVLYHAVLPQALPQFADVSIYRWEYNFRASTVMGMVGAGGIG 235
Cdd:PRK10782 129 TPMQIVRKVLLPEALPGLVNAATITLITLVGYSAMGGAVGAGGLG 173
 
Name Accession Description Interval E-value
PhnE COG3639
ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport ...
 35-275 6.43e-108

ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 442856 [Multi-domain]  Cd Length: 244  Bit Score: 312.40  E-value: 6.43e-108
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500108776  35 LLVLLIIFVASWYVGLLNFNTLANGVPAIGTLIGESLPPDFTNVASWVSPLIDTLAMSIAGTAIAVTLSVPLAFLAARNT 114
Cdd:COG3639    3 LLALLALLVWSLWGLEFDLGRLIDGLPNLADFLSRFFPPDWSYLPDLLSALLETLAIALLGTLLGAVLALPLAFLAARNL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500108776 115 SPHPVVFQVTRTLLNGLRSVPELIMGIIFVAAVGFGALPGVLALGLHSIGMVGKFFAEAIEHVDEAPVEAADAAGATRLQ 194
Cdd:COG3639   83 APNPWVRLLARRLLNVLRAIPELVWALIFVAAVGLGPFAGVLALAIHTIGFLGKLFAEAIEEIDPGPVEALRATGASRLQ 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500108776 195 VLYHAVLPQALPQFADVSIYRWEYNFRASTVMGMVGAGGIGFELMGSLRIMQYQEVSAILIVILLMVTVVDSLSGRLRKK 274
Cdd:COG3639  163 VIRYGVLPQVLPQFLSYTLYRFEINIRAATVLGLVGAGGIGLLLNEAIRLFQYDEVAAILLVILVLVLLIDLLSARLRRR 242


                 .
gi 500108776 275 F 275
Cdd:COG3639  243 L 243
PhnE TIGR01097
phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound ...
 26-275 6.85e-103

phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions]


Pssm-ID: 273441 [Multi-domain]  Cd Length: 250  Bit Score: 299.84  E-value: 6.85e-103
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500108776   26 GWRKKLGQSLLVLLIIFVASWYVGLLNFNTLANGVPAIGTLIGESLPPDFTNVASWVSPLIDTLAMSIAGTAIAVTLSVP 105
Cdd:TIGR01097   1 RRRLIRIWLLALLVALYVWAFALLGFDLARLLAGPGQMADLLGRMFPPDWSYLPRILKALLETLAMAILGTVLAAVLAVP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500108776  106 LAFLAARNTSPHPVVFQVTRTLLNGLRSVPELIMGIIFVAAVGFGALPGVLALGLHSIGMVGKFFAEAIEHVDEAPVEAA 185
Cdd:TIGR01097  81 LALLAARNITPSPWLYGLARLLLNFLRAIPELVWALIFVAAVGLGPFAGVLALAFHTVGFLGKLFAEAIEEVDPGPVEAL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500108776  186 DAAGATRLQVLYHAVLPQALPQFADVSIYRWEYNFRASTVMGMVGAGGIGFELMGSLRIMQYQEVSAILIVILLMVTVVD 265
Cdd:TIGR01097 161 RATGASKLQVIRYGVLPQVLPQFLSYTLYRFEINVRAAAVLGLVGAGGIGLELDTAIGLFDYDEVSAIILVILVVVVIID 240

                         250
                  ....*....|
gi 500108776  266 SLSGRLRKKF 275
Cdd:TIGR01097 241 LISARLRRRL 250
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 85-264 6.01e-15

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 71.16  E-value: 6.01e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500108776  85 LIDTLAMSIAGTAIAVTLSVPLAFLAARNTSPhpvVFQVTRTLLNGLRSVPELIMGIIFVAAVG---------FGALPGV 155
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGK---LDRLLRRIIDLLLSLPSLVLGLLLVLLFGvllgwgilpGLGLPAL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500108776 156 LALGLHSIGMVGKFFAEAIEHVDEAPVEAADAAGATRLQVLYHAVLPQALPQFADVSIYRWEYNFRASTVMGMVGAG--- 232
Cdd:cd06261   78 ILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGeap 157

                        170       180       190
                 ....*....|....*....|....*....|..
gi 500108776 233 GIGFELMGSLRIMQYQEVSAILIVILLMVTVV 264
Cdd:cd06261  158 GPGTGLLLIFAILFPGDLGVAAAVALILLLLS 189
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
 36-275 2.86e-14

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 70.56  E-value: 2.86e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500108776  36 LVLLIIFVASWYVGLLNFNTLANGVPAIGTLIGESLppDFTNVASWVSPLIDTLAMSIAGTAIAVTLSVPLAFLAARNts 115
Cdd:COG0600   16 LLSLALLLALWELAARLGLVPPFLLPSPSAVLAALV--ELLASGELWEHLLASLLRVLLGFALAALLGVPLGLLLGLS-- 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500108776 116 phPVVFQVTRTLLNGLRSVPELIMGIIFVAAVGFGALPGVLalglhsIGMVGKFF------AEAIEHVDEAPVEAADAAG 189
Cdd:COG0600   92 --RLLRRLLDPLLVFLRPIPPLALAPLLILWFGIGEASKIF------VIFLGAFFpillntAAGVRSVDPELLELARSLG 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500108776 190 ATRLQVLYHAVLPQALPQFADVSIYRWEYNFRASTVMGMVGAG-GIGFELMGSLRIMQYQEVSAILIVILLMVTVVDSLS 268
Cdd:COG0600  164 ASRWQILRKVVLPAALPYIFTGLRIALGLAWIGLVVAELLGASsGLGYLILDARQLLDTDLVFAAILVIGLLGLLLDLLL 243


                 ....*..
gi 500108776 269 GRLRKKF 275
Cdd:COG0600  244 RLLERRL 250
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 103-276 1.11e-13

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 67.71  E-value: 1.11e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500108776  103 SVPLAFLAARNtsPHPVVFQVTRTLLNGLRSVPELIMGIIFVAA-----VGFGALPGVLALGLHSIGMVGKFFAEAIEHV 177
Cdd:pfam00528   1 GIPLGIIAALR--RGRRLDRLLRPLIDLLQALPSFVLAILLVVIailsiLGHGILPAIILALLGWAGYARLIRRAALRSL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500108776  178 DEAPVEAADAAGATRLQVLYHAVLPQALPQFADVSIYRWEYNFRASTVMGMVGAG-GIGFELMGSLRIMQYQE----VSA 252
Cdd:pfam00528  79 PSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWpGLGLLLIEAILGYDYPEiqgpVLA 158

                         170       180
                  ....*....|....*....|....
gi 500108776  253 ILIVILLMVTVVDSLSGRLRKKFK 276
Cdd:pfam00528 159 AALILLLLNLLVDILQRLLDPRVR 182
MetP COG2011
ABC-type methionine transport system, permease component [Amino acid transport and metabolism]; ...
 85-276 4.72e-13

ABC-type methionine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 441614  Cd Length: 220  Bit Score: 66.62  E-value: 4.72e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500108776  85 LIDTLAMSIAGTAIAVTLSVPLAFL----AARNTSPHPVVFQVTRTLLNGLRSVPELIMGII------FVAAVGFGALPG 154
Cdd:COG2011   16 TGETLYMVGVSTLIAVLLGLPLGVLlvltRPGGLLPNPVLYRVLGVIVNIFRSIPFIILLVAlipltrLIVGTSIGTTAA 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500108776 155 VLALGLHSIGMVGKFFAEAIEHVDEAPVEAADAAGATRLQVLYHAVLPQALPQ------FADVSIyrweynFRASTVMGM 228
Cdd:COG2011   96 IVPLTIAAIPFFARLVENALREVDPGVIEAAQAMGASPWQIIFKVLLPEALPSlilgltVTLISL------IGYSAMAGA 169

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 500108776 229 VGAGGIgfelmGSLRIM------QYQEVSAILIVILLMVTVVDSLSGRLRKKFK 276
Cdd:COG2011  170 VGGGGL-----GDLAIRygyqrfDTDVMLVTVVILIVLVQIIQFLGDRLARRLD 218
OpuBB COG1174
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ...
 75-275 8.88e-13

ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440787 [Multi-domain]  Cd Length: 212  Bit Score: 65.85  E-value: 8.88e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500108776  75 FTNVASWVSPLIDTLAMSIAGTAIAVTLSVPLAFLAARNTSPHPVVFQVTrtllNGLRSVPELIMGIIFVAAVGFGALPG 154
Cdd:COG1174   10 ADNRDGILALLLEHLLLVLLALLIALLIAVPLGILITRRRRLAGLVLGVA----NILQTIPSLALLALLIPLLGIGPAPA 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500108776 155 VLALGLHSIGMVGKFFAEAIEHVDEAPVEAADAAGATRLQVLYHAVLPQALPQ-FADVsiyrweynfRASTVMGM----- 228
Cdd:COG1174   86 IIALVLYALLPILRNTYTGLRSVDPAVVEAARGMGMTPWQRLWRVELPLALPViLAGI---------RTAAVQNIgtatl 156

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 500108776 229 ---VGAGGIGFELMGSLRIMQYQEVSAILIVILLMVTVVDSLSGRLRKKF 275
Cdd:COG1174  157 aalIGAGGLGDLIFDGLQLNNTALILAGAILVALLALLVDLLLALLERLL 206
HisM COG0765
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ...
 74-205 3.94e-10

ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440528 [Multi-domain]  Cd Length: 218  Bit Score: 58.16  E-value: 3.94e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500108776  74 DFTNVASWVSPLIDTLAMSIAGTAIAVTLSVPLAFLAA--RnTSPHPVVFQVTRTLLNGLRSVPELImgIIFVAAVGFGA 151
Cdd:COG0765    4 DFSVLLDYLPLLLEGLLVTLLLTVLAIVLGLVLGLLLAlaR-LSPNPVLRWLATAYVEFFRGTPLLV--QLFFIYFGLPL 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 500108776 152 L--------PGVLALGLHSigmvGKFFAE----AIEHVDEAPVEAADAAGATRLQVLYHAVLPQAL 205
Cdd:COG0765   81 LgidlspfvAAVIALTLNS----AAYLAEivraGIQSVPKGQWEAARALGLSRWQTMRRIILPQAL 142
PstA COG0581
ABC-type phosphate transport system, permease component [Inorganic ion transport and ...
 96-206 1.54e-06

ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440346 [Multi-domain]  Cd Length: 259  Bit Score: 48.11  E-value: 1.54e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500108776  96 TAIAVTLSVPLAFLAA---RNTSPHPVVFQVTRTLLNGLRSVPELIMGI----IFVAAVGFG--ALPGVLALGLHSIGMV 166
Cdd:COG0581   50 VLLATLIAVPLGVLAAiylAEYARGGRLARLIRFAIDVLAGVPSIVYGLfgyaLFVLTLGLGfsLLAGALALALLMLPVV 129

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 500108776 167 GKFFAEAIEHVDEAPVEAADAAGATRLQVLYHAVLPQALP 206
Cdd:COG0581  130 IRTTEEALRLVPNSLREASYALGATKWQTIRKVVLPAALP 169
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 11-206 1.97e-05

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 45.06  E-value: 1.97e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500108776  11 LSPAPSASVLDEhakgWRKKLG--QSLLVLLIIFVAswyvGLLNFN---TLANGVPaIGTLIGESLPPdftnvaswvspl 85
Cdd:COG0601   39 LGPRATPEAIAA----LRAELGldQPLLVQYLDWLG----GLLRGDlgtSFVYGRP-VSDLIAERLPV------------ 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500108776  86 idTLAMSIAGTAIAVTLSVPLAFLAARNtsPHPVVFQVTRTLLNGLRSVPELIMGI--IFVAAVGFGALPG--------- 154
Cdd:COG0601   98 --TLELALLALLLALLIGIPLGILAALR--RGSWLDRLITVLALLGISIPSFWLGLllILLFAVKLGWLPVsgrvspwed 173

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 500108776 155 -----------VLALGLHSIGMVGKFF-AEAIEHVDEAPVEAADAAGATRLQVLYHAVLPQALP 206
Cdd:COG0601  174 fldalrhlilpALTLALGSLAGIARLTrSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALI 237
3a0107s02c TIGR00974
phosphate ABC transporter, permease protein PstA; This model describes PtsA, one of a pair of ...
 30-206 3.12e-05

phosphate ABC transporter, permease protein PstA; This model describes PtsA, one of a pair of permease proteins in the ABC (high affinity) phosphate transporter. In a number of species, this permease is fused with the PtsC protein (TIGR02138). In the model bacterium Escherichia coli, this transport system is induced when the concentration of extrallular inorganic phosphate is low. A constitutive, lower affinity transporter operates otherwise. [Transport and binding proteins, Anions]


Pssm-ID: 273373  Cd Length: 271  Bit Score: 44.53  E-value: 3.12e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500108776   30 KLGQSLLVLLIIFVASWYVGLLNFnTLANGVPAIgTLIGESLPPDFTNVASWVSP-LIDTLAMsiagTAIAVTLSVPLAF 108
Cdd:TIGR00974   2 KIFTFISLLSALLALLPLIWILWY-ILIKGLPAL-NLEFFTKSPTPTGAEGGIGPaIVGTLLL----TLLAIVIAVPLGI 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500108776  109 LAA---RNTSPHPVVFQVTRTLLNGLRSVPELIMGI----IFVAAV---GFGALPGVLALGLHSIGMVGKFFAEAIEHVD 178
Cdd:TIGR00974  76 GAAiylAEYANGSRFTKIIRFAVDILAGVPSIVVGLfgygFFVLTYlggGFSLLAGALALALLILPVIIRTTEEALKAVP 155

                         170       180
                  ....*....|....*....|....*...
gi 500108776  179 EAPVEAADAAGATRLQVLYHAVLPQALP 206
Cdd:TIGR00974 156 KDLREASLALGATKWQTIFKVVLPAALP 183
PstC COG0573
ABC-type phosphate transport system, permease component [Inorganic ion transport and ...
 34-206 3.68e-05

ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440338 [Multi-domain]  Cd Length: 303  Bit Score: 44.31  E-value: 3.68e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500108776  34 SLLVLLIIFVASWYVGLLNFNTlangVPAIGTLIGESLPPDFTNVASWVSPLIdtlAMSIAGTAIAVTLSVPLAFLAArn 113
Cdd:COG0573   31 SILILLLIVLFLLIESLPAFQE----VGLLEFLTGTEWNPVSSNGEFGILPLI---VGTLLVSLIALLIAVPLGLGIA-- 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500108776 114 tsphpvVF----------QVTRTLLNGLRSVP-------------ELIMGIIFVAAVGFGALPGVLALGLHSIGMVGKFF 170
Cdd:COG0573  102 ------IFlseyapprlrRILKPAIELLAGIPsvvygfwglfvlvPLLRDLFPWPPSGFSLLTAGIVLAIMILPTITSLS 175

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 500108776 171 AEAIEHVDEAPVEAADAAGATRLQVLYHAVLPQALP 206
Cdd:COG0573  176 RDALRAVPRSLREAALALGATRWETIRKVVLPAARS 211
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
63-209 1.17e-04

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 43.23  E-value: 1.17e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500108776  63 IGTLIGESLPPDFTNVASWVS------PLIDTLAMSIAGTAIAVTLSVPLAFLAARNTSPHPVVFQV--TRTLLnglrsV 134
Cdd:COG1178   28 LLALLLRAFTDGLANFWALLSdpylwrALGNTLLLALLVTLLSLLLGVPLAWLLARTDFPGRRLLRWllLLPLA-----L 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500108776 135 PELIMGIIFVAAVGF--------------------GALPGVLALGLHSIGMVGKFFAEAIEHVDEAPVEAADAAGATRLQ 194
Cdd:COG1178  103 PPYVVALAWIALFGPngllntllralfgleppdiyGLGGIILVLVLFNYPYVYLLLRAALRSIDASLEEAARSLGASPWR 182

                        170
                 ....*....|....*
gi 500108776 195 VLYHAVLPQALPQFA 209
Cdd:COG1178  183 AFRRVTLPLLRPAIA 197
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 88-207 1.70e-04

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 42.02  E-value: 1.70e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500108776  88 TLAMSIAGTAIAVTLSVPLAFLAARNtspHPVVFQVTRTLLNGLRSVPELIMGIIFVAAVGFGALPGVLALGLHSIGMVG 167
Cdd:COG1173   81 SLLVGLLAVLIALVIGVLLGLLAGYF---GGWVDAVLMRLVDVLLAFPSLLLAIALVAVLGPGLLNVILALGLTGWPGYA 157

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 500108776 168 KFF-AEAIEHVDEAPVEAADAAGATRLQVLYHAVLPQALPQ 207
Cdd:COG1173  158 RLVrAQVLSLREREYVEAARALGASPLRIIFRHILPNVLPP 198
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
26-270 3.52e-04

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 41.69  E-value: 3.52e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500108776  26 GWRKKLGQSLLVLLIIFVASWYVGLLNFNTLANGVPAIGTLigESLPPDFTNVASWvSPLIDTLAMSIAGTAIAVTLSVP 105
Cdd:COG1178  284 GRWRWLALALCLLLVLLGLLLPLLALLLWSLTKALDDNLTL--DNYRFVLLDPSLL-RALLNSLLLALLAALLAVLLALL 360

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500108776 106 LAFLAARNTSPhpvVFQVTRTLLNGLRSVPELIMGIIFVAAVGFGALPG--------VLALGLHSIGMVGKFFAEAIEHV 177
Cdd:COG1178  361 LAYLVRRRRGR---LARLLDRLAMLPYAVPGIVLGLGLLLLFNRPLPLLlygtlailVLAYVVRFLPFALRSLEAALAQI 437

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500108776 178 DEAPVEAADAAGATRLQVLYHAVLPQALPQFADVSIYRWeynfraSTVMGMVGA----GGIGFELMgSLRIMQ------Y 247
Cdd:COG1178  438 DPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAALLVF------VTSMKELSAtlllRPPGFETL-AVLIYQlassgrY 510

                        250       260
                 ....*....|....*....|....*..
gi 500108776 248 QEVSA----ILIVILLMVTVVDSLSGR 270
Cdd:COG1178  511 GEAAAlallLVLVSLLPVLLLERLLGR 537
PRK10782 PRK10782
D-methionine ABC transporter permease MetI;
117-235 1.62e-03

D-methionine ABC transporter permease MetI;


Pssm-ID: 182726  Cd Length: 217  Bit Score: 38.95  E-value: 1.62e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500108776 117 HPVVFQVTRTLLNGLRSVPELIMGII------FVAAVGFGALPGVLALGLHSIGMVGKFFAEAIEHVDEAPVEAADAAGA 190
Cdd:PRK10782  49 NAKLYRTLSALVNIFRSIPFIILLVWmipftrVIVGTSIGLQAAIVPLTVGAAPFIARMVENALLEIPTGLIEASRAMGA 128

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 500108776 191 TRLQVLYHAVLPQALPQFADVSIYRWEYNFRASTVMGMVGAGGIG 235
Cdd:PRK10782 129 TPMQIVRKVLLPEALPGLVNAATITLITLVGYSAMGGAVGAGGLG 173
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 79-206 1.85e-03

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 38.94  E-value: 1.85e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500108776  79 ASWVSPLIDTLAMSIAGTAIAVTLSVPLAFLAARNTSPHPVVFQvtrTLLNGLRSVPELIMGI-IFVAAVGFGALPG--- 154
Cdd:COG1177   57 PRLLDALLNSLLIALLSTLLATVLGTPAALALARYRFRGRRLLL---ALLLLPLVVPGIVLGVaLLLLFSALGLSGGlwg 133

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 500108776 155 -VLALGLHSIGMVGKFFAEAIEHVDEAPVEAADAAGATRLQVLYHAVLPQALP 206
Cdd:COG1177  134 lILAHVVFTLPFVVLVVLARLQGFDPSLEEAARDLGASPWQTFRRVTLPLIAP 186
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH