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Conserved domains on  [gi|499957344|ref|WP_011638078|]
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TonB-dependent receptor domain-containing protein [Shewanella frigidimarina]

Protein Classification

porin family protein( domain architecture ID 229388)

porin family protein is a member of a large superfamily consisting of classical (gram-negative ) porins which are non-specific channels for small hydrophillic molecules, maltoporin-like channels which have specificities for various sugars, and ligand-gated protein channels which cooperate with a TonB associated inner membrane complex to actively transport ligands via the proton motive force

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
OM_channels super family cl21487
Porin superfamily. These outer membrane channels share a beta-barrel structure that differ in ...
58-868 3.73e-51

Porin superfamily. These outer membrane channels share a beta-barrel structure that differ in strand and shear number. Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20), which associate as trimers. Maltoporin-like channels have specificities for various sugars and form 18 beta-stranded barrels (18,22), which associate as trimers. Ligand-gated protein channels cooperate with a TonB associated inner membrane complex to actively transport ligands via the proton motive force and they form monomeric, (22,24) barrels. The 150-200 N-terminal residues form a plug that blocks the channel from the periplasmic end.


The actual alignment was detected with superfamily member cd01347:

Pssm-ID: 473880 [Multi-domain]  Cd Length: 635  Bit Score: 190.36  E-value: 3.73e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  58 PITTITTEDMKMEGNFTVADALRNsnLNSFgSFSERSGSSAQsqaTINLRGAGSSRTLVLIDGKRFPGSPtlGGASANLN 137
Cdd:cd01347    1 SVSVITAEDIEKQPATSLADLLRR--IPGV-SVTRGGGGGGS---TISIRGFGPDRTLVLVDGLPLASSN--YGRGVDLN 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 138 AIPMAAVERIEILTDGASSTYGSDAIAGVVNIIMKKNYQGIEFnvgggsrdrdggltskefSVVAGYQMDKGNitfafdH 217
Cdd:cd01347   73 TIPPELIERVEVLKGPSSALYGSGAIGGVVNIITKRPTDEFGG------------------SVTAGYGSDNSG------S 128
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 218 QDRKGIsdadrdftapwmedlngdGVIQAYSETDGWSYYgasvkgpdgiyqpsplcgdlaaEYGDNVFKQVRGDDQFGAG 297
Cdd:cd01347  129 SGGGGF------------------DVSGALADDGAFGAR----------------------LYGAYRDGDGTIDGDGQAD 168
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 298 SdlcmyaygnvsynkASTDRNTVYVDANYEIAEDLEWFGRVMVTQSNSFGRYAPPAANWNNMAADNPHNPFDVEAKGYfr 377
Cdd:cd01347  169 D--------------SDEERYNVAGKLDWRPDDDTRLTLDAGYQDQDADGPGGTLPANGTGSSLGGGPSSNTNGDRDW-- 232
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 378 wvgigTRDGNVDDYNQDYLTGLrgtisaLNDAEWEVY--YHHNIADNKSIGEYYLSYsglayNEANGIDLGSEAGINNMK 455
Cdd:cd01347  233 -----DYRDRYRKRASLGLEHD------LNDTGWTLRanLSYSYTDNDGDPLILNGG-----NNAAGGDLGRSGYSSERD 296
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 456 ATtltqgsaifdQYNAGIGFDAfELPGGSVAHY--VGLEYFDQQYsevydaqseagliggsagnsaagDRQVWAMFYEAV 533
Cdd:cd01347  297 TT----------QLGFDAGLNA-PFGTGPVAHTltLGVEYRREEL-----------------------DEKQTALYAQDT 342
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 534 LPITDDIELNLAARYDDY--------------SDFGDNIAPKAAIRWQALENVVVRASYSEAFRAPALDQLFAATTFSAe 599
Cdd:cd01347  343 IELTDDLTLTLGLRYDHYdqdskdtiaggttaKKSYSHWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELYGGGSHGG- 421
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 600 dgidkpyceatgtpcserqfdTYISANKELGPETSQYVNFGVAWDIVDDIGLKVDYFNLNIDDVIAQRSITSVMTGIyeg 679
Cdd:cd01347  422 ---------------------TAAVGNPNLKPEKSKQYELGLKYDPGDGLTLSAALFRIDIKNEIVSTPTNTGLGLV--- 477
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 680 tlapsntfyvkrdpasagqaigaasevgTGYSNANTLEISGIDVALNAKFetnigDIGFNWTNSFVLDYTEEVDGGAESR 759
Cdd:cd01347  478 ----------------------------TVYVNGGKARIRGVELEASYDL-----TDGLGLTGSYTYTDTEVKRTDGATT 524
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 760 DTSGWNgQPDYKSVFTTNYRMGDH--SLSWNMNYTSSTFY-FEDDASKGELDSWLIHNISYVYDAGNYGSILLGINNLTD 836
Cdd:cd01347  525 GNRLPG-IPKHTANLGLDYELPDEglTAGGGVRYRGKQYAdTANGNNTVKVPGYTLVDLSASYQFTKNLTLRLGVNNLFD 603
                        810       820       830
                 ....*....|....*....|....*....|..
gi 499957344 837 EDPVLSPDGKFENADLYNNYGREYRASYTLKF 868
Cdd:cd01347  604 KDYYTSLSVRGSGLYGYYGPGRTYYLSVSYKF 635
 
Name Accession Description Interval E-value
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
58-868 3.73e-51

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 190.36  E-value: 3.73e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  58 PITTITTEDMKMEGNFTVADALRNsnLNSFgSFSERSGSSAQsqaTINLRGAGSSRTLVLIDGKRFPGSPtlGGASANLN 137
Cdd:cd01347    1 SVSVITAEDIEKQPATSLADLLRR--IPGV-SVTRGGGGGGS---TISIRGFGPDRTLVLVDGLPLASSN--YGRGVDLN 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 138 AIPMAAVERIEILTDGASSTYGSDAIAGVVNIIMKKNYQGIEFnvgggsrdrdggltskefSVVAGYQMDKGNitfafdH 217
Cdd:cd01347   73 TIPPELIERVEVLKGPSSALYGSGAIGGVVNIITKRPTDEFGG------------------SVTAGYGSDNSG------S 128
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 218 QDRKGIsdadrdftapwmedlngdGVIQAYSETDGWSYYgasvkgpdgiyqpsplcgdlaaEYGDNVFKQVRGDDQFGAG 297
Cdd:cd01347  129 SGGGGF------------------DVSGALADDGAFGAR----------------------LYGAYRDGDGTIDGDGQAD 168
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 298 SdlcmyaygnvsynkASTDRNTVYVDANYEIAEDLEWFGRVMVTQSNSFGRYAPPAANWNNMAADNPHNPFDVEAKGYfr 377
Cdd:cd01347  169 D--------------SDEERYNVAGKLDWRPDDDTRLTLDAGYQDQDADGPGGTLPANGTGSSLGGGPSSNTNGDRDW-- 232
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 378 wvgigTRDGNVDDYNQDYLTGLrgtisaLNDAEWEVY--YHHNIADNKSIGEYYLSYsglayNEANGIDLGSEAGINNMK 455
Cdd:cd01347  233 -----DYRDRYRKRASLGLEHD------LNDTGWTLRanLSYSYTDNDGDPLILNGG-----NNAAGGDLGRSGYSSERD 296
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 456 ATtltqgsaifdQYNAGIGFDAfELPGGSVAHY--VGLEYFDQQYsevydaqseagliggsagnsaagDRQVWAMFYEAV 533
Cdd:cd01347  297 TT----------QLGFDAGLNA-PFGTGPVAHTltLGVEYRREEL-----------------------DEKQTALYAQDT 342
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 534 LPITDDIELNLAARYDDY--------------SDFGDNIAPKAAIRWQALENVVVRASYSEAFRAPALDQLFAATTFSAe 599
Cdd:cd01347  343 IELTDDLTLTLGLRYDHYdqdskdtiaggttaKKSYSHWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELYGGGSHGG- 421
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 600 dgidkpyceatgtpcserqfdTYISANKELGPETSQYVNFGVAWDIVDDIGLKVDYFNLNIDDVIAQRSITSVMTGIyeg 679
Cdd:cd01347  422 ---------------------TAAVGNPNLKPEKSKQYELGLKYDPGDGLTLSAALFRIDIKNEIVSTPTNTGLGLV--- 477
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 680 tlapsntfyvkrdpasagqaigaasevgTGYSNANTLEISGIDVALNAKFetnigDIGFNWTNSFVLDYTEEVDGGAESR 759
Cdd:cd01347  478 ----------------------------TVYVNGGKARIRGVELEASYDL-----TDGLGLTGSYTYTDTEVKRTDGATT 524
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 760 DTSGWNgQPDYKSVFTTNYRMGDH--SLSWNMNYTSSTFY-FEDDASKGELDSWLIHNISYVYDAGNYGSILLGINNLTD 836
Cdd:cd01347  525 GNRLPG-IPKHTANLGLDYELPDEglTAGGGVRYRGKQYAdTANGNNTVKVPGYTLVDLSASYQFTKNLTLRLGVNNLFD 603
                        810       820       830
                 ....*....|....*....|....*....|..
gi 499957344 837 EDPVLSPDGKFENADLYNNYGREYRASYTLKF 868
Cdd:cd01347  604 KDYYTSLSVRGSGLYGYYGPGRTYYLSVSYKF 635
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
33-827 1.13e-50

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 188.53  E-value: 1.13e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  33 EDGAKVERIEVTGSRIKRSDLEGASPITTITTEDMKMEGNFTVADALRNSNlnsfgSFSERSGSSAQSQATINLRGAGSS 112
Cdd:COG4771   22 EDATELEEVVVTATRTEQSLSDAPASVSVITAEEIEKLGATDLADALRLLP-----GVSVTRSGGRGGSSGISIRGLGGD 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 113 RTLVLIDGKRFPGSPTLGGAsaNLNAIPMAAVERIEILTDGASSTYGSDAIAGVVNIIMKKNYQGIEFNVGGGSRDRDGG 192
Cdd:COG4771   97 RVLVLIDGVPVNNPALGGGG--DLSYIPPDDIERIEVIRGPASALYGSDAIGGVINIITKKPTDELEGSVSLGYGSNGNG 174
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 193 LTSkeFSVVAGYQMDKGNITFAFDHQDRKGISDADRDFTAPWmedlngdgviqaysetdgwsyygasvkgpdgiyqpspl 272
Cdd:COG4771  175 TYS--GSLSLGGPGDKLSFLLSGSYRDRDGYLDYRNGGFVGN-------------------------------------- 214
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 273 cgdlaaeygdnvfkqvrgddqfgagsdlcmyaygnvsynkASTDRNTVYVDANYEIAEDLEWFGRVMVTQSNSFGRYAPP 352
Cdd:COG4771  215 ----------------------------------------SGYERYNLNAKLGYRLSDNHRLSLSGGYSRQDRDGGPPTL 254
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 353 AANWNNMAADNPhnpfdveakgyfrwvgigtRDGNVDDYNqdyltglrgtisalndaeWEVYYHHNIADNksiGEYYLSY 432
Cdd:COG4771  255 GDTEISSDNAGD-------------------RDTTTDRGN------------------YSLRYNGDLGDN---LDLSLYY 294
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 433 SGLAYNEANGIDLGSEAGINNMKATTLTQGSaifdQYNAGIGfDAFELpggsvahYVGLEYFDQQYSEvydaqseaglig 512
Cdd:COG4771  295 SRTDRDSTNGSLGGSTGSFSDSDDTTYGLEL----DLTYPLG-GNHTL-------TLGAEYRYDDLDS------------ 350
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 513 GSAGNSAAGDRQVWAMFYEAVLPITDDIELNLAARYDDYSDFG----DNIAPKAAIRWQALENVVVRASYSEAFRAPALD 588
Cdd:COG4771  351 SSFLGGADASRDTYGLFAQDEWKLTDKLTLTAGLRYDYYSTFGasnyTAFSPRLGLRYDLSDNLTLRASYGRGFRAPSLA 430
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 589 QLFAATTFSAedgidkpyceatgtpcserqfDTYISANKELGPETSQYVNFGVAWDIVDD-IGLKVDYFNLNIDDVIAQR 667
Cdd:COG4771  431 ELYGSGTGTP---------------------GRYVLGNPDLKPETSDNYELGLEYRLGNGgLSLSLTGFYTDIKDLIVLV 489
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 668 SITSVMTGIYegtlapsntfyvkrdpasagqaigaasevgtGYSNANTLEISGIDVALNAKFETNI-GDIGFNWTNSfvl 746
Cdd:COG4771  490 PVGPGPGDVL-------------------------------QYENVGKARTYGLELELKYRLGKGLtLTASYTYLDS--- 535
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 747 dyteEVDGGAESRDtsgWNGQPDYKSVFTTNYRMGDH--SLSWNMNYTSSTFYFEDDASKGELDSWLIHNISYVYDAGNY 824
Cdd:COG4771  536 ----KIDDGDTGEP---LPNVPPHKANLGLDYRLPKWwlLLLLTRYYGGRYVTPPSGRLEGYTPGYTLLDLRASYKLTKN 608

                 ...
gi 499957344 825 GSI 827
Cdd:COG4771  609 LTL 611
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
355-867 1.15e-29

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 123.73  E-value: 1.15e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  355 NWNNMAADNPHNPFDVEAKGYFRWVG------IGTRDGNVDDYNQDYLTGLRGTISALNDAEWEVYYHHNIADNKSIGEY 428
Cdd:pfam00593   1 GWQLSLDLLGDDTLLTLGYDYSRYTDgldlglTLDGYGNDGGYLGDRPLYYGRDYSDTDRKRLSLGYDYDLGDGLSWLST 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  429 YLSYSGLAYNEANGIDLGSEAGINNMKATTLTQGSAIFDQYNAGIGFDA-FELPGGSVAHYVGLEYFDQQYsevyDAQSE 507
Cdd:pfam00593  81 LRLGLRYSSLDGDYTSNSSGLSGAGDYLSDDRLYGLYGLDGDLELSLDLsHDLLLGVELRTAGLDYRRLDD----DAYDP 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  508 AGLIGGSAGNSAAGDRQVWAMFYEAVLPITDDIELNLAARYDDYSDFGDNIA--------------PKAAIRWQALENVV 573
Cdd:pfam00593 157 YDPANPSSSSYSDTTTDSYGLYLQDNIKLTDRLTLTLGLRYDHYSTDGDDGNgggdnfsrsysafsPRLGLVYKPTDNLS 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  574 VRASYSEAFRAPALDQLFAATtfsaedgidkpyceatgtpcSERQFDTYISANKELGPETSQYVNFGVAWDiVDDIGLKV 653
Cdd:pfam00593 237 LYASYSRGFRAPSLGELYGSG--------------------SGGGGGAVAGGNPDLKPETSDNYELGLKYD-DGRLSLSL 295
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  654 DYFNLNIDDVIAQRSITSVMTGIYegtlapsntfyvkrdpasagqaigaasevgTGYSNANTLEISGIDVALNAKFETNI 733
Cdd:pfam00593 296 ALFYIDIKNLITSDPDGPGLGGTV------------------------------YTYTNVGKARIRGVELELSGRLWGLG 345
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  734 GDIGfnwtnsfVLDYTEEVDGGAESRDTSGWNGQPDYKSVFTTNYR--MGDHSLSWNMNYTS-STFYFEDDASKGELDSW 810
Cdd:pfam00593 346 LSGG-------GYTYTDADDDADADDTGNPLPNVPRHTANLGLTYDfpLGGWGARLGARYVGsGERRYGDAANTFKTPGY 418
                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 499957344  811 LIHNISYVYDAGNYGSILLGINNLTDEDPVLSPDGKFENADLYNNYGREYRASYTLK 867
Cdd:pfam00593 419 TLVDLSAGYRLNKNLTLRLGVNNLFDKYYKRYYSSGGGNLGGYPGPGRTFYLGLSYK 475
PRK10064 PRK10064
catecholate siderophore receptor CirA; Provisional
43-868 2.02e-22

catecholate siderophore receptor CirA; Provisional


Pssm-ID: 236646 [Multi-domain]  Cd Length: 663  Bit Score: 103.04  E-value: 2.02e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  43 VTGSRIKRSDLEGASPITTITTEDMKMEGNFTVADALRnsnlnsfgsfsERSG----SSAQSQATINLRGAGSSRTLVLI 118
Cdd:PRK10064  35 VTASAVEQNLKDAPASISVITQEDLQRKPVQNLKDVLK-----------EVPGvqltNEGDNRKGVSIRGLDSSYTLILI 103
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 119 DGKRFPG-SPTLGGASANLNAIPMAAVERIEILTDGASSTYGSDAIAGVVNIIMKKNYQgiefnvgggsrdrdggltske 197
Cdd:PRK10064 104 DGKRVNSrNAVFRHNDFDLNWIPVDAIERIEVVRGPMSSLYGSDALGGVVNIITKKIGQ--------------------- 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 198 fsvvagyqmdkgnitfafdhqdrkgisdadrdftaPWMEDLNGDGVIQAYSETdGWSYYGasvkgpdGIYQPSPLCGDLa 277
Cdd:PRK10064 163 -----------------------------------KWHGTVTVDTTIQEHRDR-GDTYNG-------QFFTSGPLIDGV- 198
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 278 aeygdnvfkqvrgddqfgagsdLCMYAYGNVSYNKASTDRNTVYVDANyeIAEDLEWFgrvmvTQSNSFGRYAPPAANWN 357
Cdd:PRK10064 199 ----------------------LGMKAYGSLAKREKDDPQNSTTTDTG--ETPRIEGF-----TSRDGNVEFAWTPNQNH 249
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 358 NMAAdnphnpfdveakGYfrwvGIGTRDGNVDDYNQDYLTglRGTISALNDAEW-----EVYYHHNIADNKSIGEyylsy 432
Cdd:PRK10064 250 DFTA------------GY----GFDRQDRDSDSLDKNRLE--RQNYSLSHNGRWdygnsELKYYGEKVENKNPGN----- 306
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 433 SGLAYNEANGIDlgseaginnmkattltqgsaifdqynagigfDAFELPGGSVAHYV--GLEYfdqQYSEVYDAqseAGL 510
Cdd:PRK10064 307 SSPITSESNSID-------------------------------GKYTLPLTAINQFLtfGGEW---RHDKLSDA---VNL 349
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 511 IGGSAGNSAAgdRQvWAMFYEAVLPITDDIELNLAARYDDYSDFGDNIAPKAAIRWQALENVVVRASYSEAFRAPALDQL 590
Cdd:PRK10064 350 TGGTSSKTSA--SQ-YALFVEDEWRIFEPLALTTGVRMDDHETYGDHWSPRAYLVYNATDTVTVKGGWATAFKAPSLLQL 426
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 591 FAA-TTFSAEDGidkpyCEATGTPcserqfdtyisankELGPETSQYVNFGVAWD----IVDDIGLKVDYFNLNIDDVIA 665
Cdd:PRK10064 427 SPDwTSNSCRGA-----CKIVGSP--------------DLKPETSESWELGLYYMgeegWLEGVESSVTVFRNDVDDRIS 487
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 666 QRSITSVmtgiyegTLAPSNTFYVKRDPASAGQAIGAASevgtgYSNANTLEISGIDVALNAKFETNIgDIGFNWTNSFV 745
Cdd:PRK10064 488 ISRTSDV-------NAAPGYQNFVGFETNGRGRRVPVFR-----YYNVNKARIQGVETELKIPFNDEW-KLSLNYTYNDG 554
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 746 LDYTEEVDGGAESRDTSGWNGQPDYKSVFTTnyrmgDHSLSWNMNYTSSTFYF-EDDASKGELDSWlihNISYVYDAGNY 824
Cdd:PRK10064 555 RDVSNGENKPLSDLPFHTANGTLDWKPLALE-----DWSFYVSGNYTGQKRADsATAKTPGGYTIW---NTGAAWQVTKD 626
                        810       820       830       840
                 ....*....|....*....|....*....|....*....|....
gi 499957344 825 GSILLGINNLTDEDpvLSPDgKFEnadlYNNYGREYRASYTLKF 868
Cdd:PRK10064 627 VKLRAGVLNLGDKD--LSRD-DYS----YNEDGRRYFMAVDYRF 663
TonB-hemin TIGR01785
TonB-dependent heme/hemoglobin receptor family protein; This model represents the ...
39-868 1.05e-20

TonB-dependent heme/hemoglobin receptor family protein; This model represents the TonB-dependent outer membrane heme/hemoglobin receptor/transporter found in bacteria which live in contact with animals (which contain hemoglobin or other heme-bearing globins) or legumes (which contain leghemoglobin). Some species having hits to this model such as Nostoc, Caulobacter and Chlorobium do not have an obvious source of hemoglobin-like proteins in their biological niche and so the possibility exists that they act on some other substance. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273807 [Multi-domain]  Cd Length: 665  Bit Score: 97.46  E-value: 1.05e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344   39 ERIEVTGSRIKRSDLEGASPITTITTEDMKMEGNFTVADALRN-SNLnsfgSFSERSGSSAQSqatINLRGAGSSRTLVL 117
Cdd:TIGR01785   2 DTVTVTATRTRQVLSEAPASVSVISGEQIESKQANNLADALNTvPGV----DVTGGGRPPGQS---INIRGLQDNRVLVV 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  118 IDGKRFPGspTLGGASANLNAIPMAAVERIEILTDGASSTYGSDAIAGVVNIIMKKNYQGIEFNvgggsrdrdggltsKE 197
Cdd:TIGR01785  75 VDGARQNY--QRGGAHNGSLFVDPELLKRIEIVKGPSSSLYGSGALGGVVAFRTKDAADLLRPG--------------QL 138
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  198 FSVVAGYQMDKGNITFAFDHqdrkgiSDADRdftapwmEDLNGDGVIQAYsetdgwsyygasvkgpdgiyqpsplcgdla 277
Cdd:TIGR01785 139 FGGLAKLSYGSNNNSFGGSV------AVAGR-------LDDNLDALVAAT------------------------------ 175
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  278 aeygdnvfkqVRGDDQFGAGSDLCMYAYGNVSYNKAStdRNTVYVDANYEIAedlewFGrvMVTQSNSfgryappaanwn 357
Cdd:TIGR01785 176 ----------YRDGGNYRNGNKEEATNSAYVQKNLLA--KLGWQLDDAQRLE-----FS--YFTTEGS------------ 224
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  358 nmaADNPHNPFDVEAKGYFRWVGIGTRDGNVDDYNQDYLTGLRGtiSALNDAEWEVYYHHNIADNKSIGEYYLSYSGLAY 437
Cdd:TIGR01785 225 ---LDEAQNSGPGTEYVLGSSSTLLASSTRDRSATLTYNWTPED--NPWLDATASLYYNRTENDNDRSARGVGREEGYQY 299
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  438 NEaNGIDLgseagiNNmkattltqgsaifdqynagigfdAFELPGGSVAHYV-GLEYFDQQYSEVYDAQSEAGLIggsAG 516
Cdd:TIGR01785 300 TT-YGATL------QN-----------------------TSRFDVASWSTLTyGVDWMKDKRRTESFDPNSVTTI---VP 346
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  517 NSAAGDRQVWAMFYEAVLPITDD-IELNLAARYD------------DYSDFGDN-IAPKAAIRWQALENVVVRASYSEAF 582
Cdd:TIGR01785 347 NPPSAKEYFFGLFLQDNIPLLDDrLTLSAGLRYDhyklspkttadtEAVDRSYSrWSPSLGLSYKPVDWLTLYASYSQGF 426
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  583 RAPALDQLFAAttfSAEDGIDKPYCeatgtpcserqfdtyISANKELGPETS--QYVNFGVAWDIV----DDIGLKVDYF 656
Cdd:TIGR01785 427 RAPSIDELYGT---GDHPGTPGGYT---------------FAPNPNLKPETSktWELGANLSFDNLlldnDQLQFKVAYF 488
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  657 NLNIDDVIAQRSitsvmtGIYEGTLAPSNTFyvkrdpasagqaigaasevgTGYSNANTLEISGIDVALNAKFEtnigdi 736
Cdd:TIGR01785 489 YNDVKDFIDLTI------GVTDNVTAGMNNI--------------------TQYVNIDGARIRGIEASASYDAG------ 536
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  737 gfNWTNSFVLDYTEevdgGAESRDTSGWNGQPDYKSVFTTNYRMGDH--SLSWNMNYT---SSTFYFEDDASKG--ELDS 809
Cdd:TIGR01785 537 --LWATGLSYGYTI----GKDQNTNQWLSNIPPLKLVVTVGYRFPDRrlDLGAKAAYYerqSESPTTEDVAANGllTTPG 610
                         810       820       830       840       850       860
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 499957344  810 WLIHNI--SYVYDAGNYGSILLGINNLTDEDPVLSPDgkfenaDLYNNYGREYRASYTLKF 868
Cdd:TIGR01785 611 YTVVDLyaTYQPNAVKGLTVRFGVNNLTDRKYTPAQS------VPGAGPGRNFKGSVKYQF 665
 
Name Accession Description Interval E-value
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
58-868 3.73e-51

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 190.36  E-value: 3.73e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  58 PITTITTEDMKMEGNFTVADALRNsnLNSFgSFSERSGSSAQsqaTINLRGAGSSRTLVLIDGKRFPGSPtlGGASANLN 137
Cdd:cd01347    1 SVSVITAEDIEKQPATSLADLLRR--IPGV-SVTRGGGGGGS---TISIRGFGPDRTLVLVDGLPLASSN--YGRGVDLN 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 138 AIPMAAVERIEILTDGASSTYGSDAIAGVVNIIMKKNYQGIEFnvgggsrdrdggltskefSVVAGYQMDKGNitfafdH 217
Cdd:cd01347   73 TIPPELIERVEVLKGPSSALYGSGAIGGVVNIITKRPTDEFGG------------------SVTAGYGSDNSG------S 128
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 218 QDRKGIsdadrdftapwmedlngdGVIQAYSETDGWSYYgasvkgpdgiyqpsplcgdlaaEYGDNVFKQVRGDDQFGAG 297
Cdd:cd01347  129 SGGGGF------------------DVSGALADDGAFGAR----------------------LYGAYRDGDGTIDGDGQAD 168
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 298 SdlcmyaygnvsynkASTDRNTVYVDANYEIAEDLEWFGRVMVTQSNSFGRYAPPAANWNNMAADNPHNPFDVEAKGYfr 377
Cdd:cd01347  169 D--------------SDEERYNVAGKLDWRPDDDTRLTLDAGYQDQDADGPGGTLPANGTGSSLGGGPSSNTNGDRDW-- 232
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 378 wvgigTRDGNVDDYNQDYLTGLrgtisaLNDAEWEVY--YHHNIADNKSIGEYYLSYsglayNEANGIDLGSEAGINNMK 455
Cdd:cd01347  233 -----DYRDRYRKRASLGLEHD------LNDTGWTLRanLSYSYTDNDGDPLILNGG-----NNAAGGDLGRSGYSSERD 296
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 456 ATtltqgsaifdQYNAGIGFDAfELPGGSVAHY--VGLEYFDQQYsevydaqseagliggsagnsaagDRQVWAMFYEAV 533
Cdd:cd01347  297 TT----------QLGFDAGLNA-PFGTGPVAHTltLGVEYRREEL-----------------------DEKQTALYAQDT 342
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 534 LPITDDIELNLAARYDDY--------------SDFGDNIAPKAAIRWQALENVVVRASYSEAFRAPALDQLFAATTFSAe 599
Cdd:cd01347  343 IELTDDLTLTLGLRYDHYdqdskdtiaggttaKKSYSHWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELYGGGSHGG- 421
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 600 dgidkpyceatgtpcserqfdTYISANKELGPETSQYVNFGVAWDIVDDIGLKVDYFNLNIDDVIAQRSITSVMTGIyeg 679
Cdd:cd01347  422 ---------------------TAAVGNPNLKPEKSKQYELGLKYDPGDGLTLSAALFRIDIKNEIVSTPTNTGLGLV--- 477
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 680 tlapsntfyvkrdpasagqaigaasevgTGYSNANTLEISGIDVALNAKFetnigDIGFNWTNSFVLDYTEEVDGGAESR 759
Cdd:cd01347  478 ----------------------------TVYVNGGKARIRGVELEASYDL-----TDGLGLTGSYTYTDTEVKRTDGATT 524
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 760 DTSGWNgQPDYKSVFTTNYRMGDH--SLSWNMNYTSSTFY-FEDDASKGELDSWLIHNISYVYDAGNYGSILLGINNLTD 836
Cdd:cd01347  525 GNRLPG-IPKHTANLGLDYELPDEglTAGGGVRYRGKQYAdTANGNNTVKVPGYTLVDLSASYQFTKNLTLRLGVNNLFD 603
                        810       820       830
                 ....*....|....*....|....*....|..
gi 499957344 837 EDPVLSPDGKFENADLYNNYGREYRASYTLKF 868
Cdd:cd01347  604 KDYYTSLSVRGSGLYGYYGPGRTYYLSVSYKF 635
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
33-827 1.13e-50

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 188.53  E-value: 1.13e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  33 EDGAKVERIEVTGSRIKRSDLEGASPITTITTEDMKMEGNFTVADALRNSNlnsfgSFSERSGSSAQSQATINLRGAGSS 112
Cdd:COG4771   22 EDATELEEVVVTATRTEQSLSDAPASVSVITAEEIEKLGATDLADALRLLP-----GVSVTRSGGRGGSSGISIRGLGGD 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 113 RTLVLIDGKRFPGSPTLGGAsaNLNAIPMAAVERIEILTDGASSTYGSDAIAGVVNIIMKKNYQGIEFNVGGGSRDRDGG 192
Cdd:COG4771   97 RVLVLIDGVPVNNPALGGGG--DLSYIPPDDIERIEVIRGPASALYGSDAIGGVINIITKKPTDELEGSVSLGYGSNGNG 174
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 193 LTSkeFSVVAGYQMDKGNITFAFDHQDRKGISDADRDFTAPWmedlngdgviqaysetdgwsyygasvkgpdgiyqpspl 272
Cdd:COG4771  175 TYS--GSLSLGGPGDKLSFLLSGSYRDRDGYLDYRNGGFVGN-------------------------------------- 214
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 273 cgdlaaeygdnvfkqvrgddqfgagsdlcmyaygnvsynkASTDRNTVYVDANYEIAEDLEWFGRVMVTQSNSFGRYAPP 352
Cdd:COG4771  215 ----------------------------------------SGYERYNLNAKLGYRLSDNHRLSLSGGYSRQDRDGGPPTL 254
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 353 AANWNNMAADNPhnpfdveakgyfrwvgigtRDGNVDDYNqdyltglrgtisalndaeWEVYYHHNIADNksiGEYYLSY 432
Cdd:COG4771  255 GDTEISSDNAGD-------------------RDTTTDRGN------------------YSLRYNGDLGDN---LDLSLYY 294
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 433 SGLAYNEANGIDLGSEAGINNMKATTLTQGSaifdQYNAGIGfDAFELpggsvahYVGLEYFDQQYSEvydaqseaglig 512
Cdd:COG4771  295 SRTDRDSTNGSLGGSTGSFSDSDDTTYGLEL----DLTYPLG-GNHTL-------TLGAEYRYDDLDS------------ 350
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 513 GSAGNSAAGDRQVWAMFYEAVLPITDDIELNLAARYDDYSDFG----DNIAPKAAIRWQALENVVVRASYSEAFRAPALD 588
Cdd:COG4771  351 SSFLGGADASRDTYGLFAQDEWKLTDKLTLTAGLRYDYYSTFGasnyTAFSPRLGLRYDLSDNLTLRASYGRGFRAPSLA 430
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 589 QLFAATTFSAedgidkpyceatgtpcserqfDTYISANKELGPETSQYVNFGVAWDIVDD-IGLKVDYFNLNIDDVIAQR 667
Cdd:COG4771  431 ELYGSGTGTP---------------------GRYVLGNPDLKPETSDNYELGLEYRLGNGgLSLSLTGFYTDIKDLIVLV 489
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 668 SITSVMTGIYegtlapsntfyvkrdpasagqaigaasevgtGYSNANTLEISGIDVALNAKFETNI-GDIGFNWTNSfvl 746
Cdd:COG4771  490 PVGPGPGDVL-------------------------------QYENVGKARTYGLELELKYRLGKGLtLTASYTYLDS--- 535
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 747 dyteEVDGGAESRDtsgWNGQPDYKSVFTTNYRMGDH--SLSWNMNYTSSTFYFEDDASKGELDSWLIHNISYVYDAGNY 824
Cdd:COG4771  536 ----KIDDGDTGEP---LPNVPPHKANLGLDYRLPKWwlLLLLTRYYGGRYVTPPSGRLEGYTPGYTLLDLRASYKLTKN 608

                 ...
gi 499957344 825 GSI 827
Cdd:COG4771  609 LTL 611
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
38-838 4.94e-38

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 151.52  E-value: 4.94e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  38 VERIEVTGSRIKRSDLEGASPITTITTEDMKMEGNFTVADALRN-SNLNSfgsfsersGSSAQSQATINLRG--AGSSRT 114
Cdd:COG1629    1 LEEVVVTATRTDESLQDVPGSVSVISREQLEDQPATDLGDLLRRvPGVSV--------TSAGGGAGQISIRGfgGGGNRV 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 115 LVLIDGKRFPGSptlGGASANLNAIPMAAVERIEILTDGASSTYGSDAIAGVVNIIMKKNYQGIEFNVGGGSRDRDGglt 194
Cdd:COG1629   73 LVLVDGVPLNDP---SGGDGGLSYIDPEDIERVEVLRGPSSALYGSGALGGVINIVTKKPKDGKGGEVSASYGSYGT--- 146
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 195 sKEFSVVAGYQMDKGNITFAFDHQDRKGisdadrdftapwmedlngdgviqaysetdgwsyygasvkgpdgiyqpsplcg 274
Cdd:COG1629  147 -YRASLSLSGGNGKLAYRLSASYRDSDG---------------------------------------------------- 173
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 275 dlaaeYGDNvfkqvrgddqfgagsdlcmyaygnvsynkASTDRNTVYVDANYEIAEDlewfGRVMVTqsnsfgryappaA 354
Cdd:COG1629  174 -----YRDN-----------------------------SDSDRYNLRAKLGYQLGDD----TRLTLS------------A 203
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 355 NWNNMAADNPHNPFDVEAKGYFRWVGIGTRDGNVDDYNQDYLTGLRGTISALNDAewevyyhhniadnksigeyyLSYSG 434
Cdd:COG1629  204 SYSDSDQDSPGYLTLAALRPRGAMDDGTNPYSNDTDDNTRDRYSLSLEYEHLGDG--------------------LKLSA 263
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 435 LAYNEANGIDLGSEAGINNMKATTLTQGSAIFDQYNAGIGFDAFELPGGSVAHYVGLEYFDQQY-SEVYDAQSEAGLIGG 513
Cdd:COG1629  264 SAYYRYDDTDLDSDFTPTPADGGTLEQTDFDNRTYGLELRLTYDLGFGGKHTLLVGLDYQRQDLdGSGYPLDLGSGSLPT 343
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 514 SA-GNSAAGDRQVWAMFYEAVLPITDDIELNLAARYDDYSDFGD----------------NIAPKAAIRWQALENVVVRA 576
Cdd:COG1629  344 LTsGADDDGTTTSLALYAQDTYKLTDKLTLTAGLRYDYVSYDVDdtvtgtdsasgsrsysAFSPSLGLTYQLSPNLSLYA 423
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 577 SYSEAFRAPALDQLFAATTfsaedgidkpyceatgtpcserqfDTYISANKELGPETSQYVNFGVAWDIVDD-IGLKVDY 655
Cdd:COG1629  424 SYSRGFRAPTFGELYANGT------------------------DPYSVGNPDLKPETSTNYELGLRYRLLDGrLSLSLAL 479
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 656 FNLNIDDVIAQrsitsvmtgiyegtlapsntfyvkrdpasagQAIGAASEVGTGYSNANTLEISGIDVALNAKFetnigD 735
Cdd:COG1629  480 FYSDVDNEILS-------------------------------VPLPNDSGFSTYYTNAGKARSYGVELELSYQL-----T 523
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 736 IGFNWTNSFVLDYTEEVDGGAESRDTSG--WNGQPDYKSVFTTNYRMGDH-SLSWNMNYTSStFYFEDDASKGELDSWLI 812
Cdd:COG1629  524 PGLSLNASYSYTDAKFDDDTDGSADLDGnrLPGVPPLTANLGLTYEFPGGwSLGLGVRYVGD-RYLDDANTQGAPGGYTL 602
                        810       820
                 ....*....|....*....|....*.
gi 499957344 813 HNISYVYDAGNYGSILLGINNLTDED 838
Cdd:COG1629  603 VDLGAGYRFGDNLTLSLGVDNLFDKK 628
BtuB COG4206
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
41-334 5.13e-31

Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];


Pssm-ID: 443355 [Multi-domain]  Cd Length: 276  Bit Score: 123.06  E-value: 5.13e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  41 IEVTGSRIKRSDLEGASPITTITTEDMKMEGNFTVADALRNsnlnsFGSFSERSGSSAQSQATINLRGAGSSRTLVLIDG 120
Cdd:COG4206    1 VVVTATRLEQSKSDLTGSVTVIDAEELERSGATSLADALRR-----VPGVQVSSSGGPGSAASISIRGLGSNQTLVLIDG 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 121 KRFpGSPTLGGAsaNLNAIPMAAVERIEILTDGASSTYGSDAIAGVVNIIMKKNYQGIEFNVGGGSRDRdgglTSKEFSV 200
Cdd:COG4206   76 VPL-NDPSLGGV--DLSLIPPDDIERIEVLKGAASALYGSDAIGGVINITTKKGKKGFKGSVSASYGSF----GTRRLSA 148
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 201 VAGYQMDKGNITFAFDHQDRKGISDADRDFTAP-WMEDLNGDGVIQ-AYSETDGWSYYGASVKGPDGIYQPSPlcgdlaa 278
Cdd:COG4206  149 SLSGGAGKFSYSLSASYRRSDGYRYNDPDLRNNdGYENTSLNARLGyKLGDNGSLSLSGGYSDSERGYPGAVG------- 221
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 499957344 279 eYGDNVFKQVRGDDQFGAGSDLCMYAYGNVSYNKASTDRNTVYVDANYEIAEDLEW 334
Cdd:COG4206  222 -SDRNLRLSLSLEYKLSDGWSLLLLAYYYYDRDYEDGGGDSAGTSNTDGARAGLSY 276
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
355-867 1.15e-29

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 123.73  E-value: 1.15e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  355 NWNNMAADNPHNPFDVEAKGYFRWVG------IGTRDGNVDDYNQDYLTGLRGTISALNDAEWEVYYHHNIADNKSIGEY 428
Cdd:pfam00593   1 GWQLSLDLLGDDTLLTLGYDYSRYTDgldlglTLDGYGNDGGYLGDRPLYYGRDYSDTDRKRLSLGYDYDLGDGLSWLST 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  429 YLSYSGLAYNEANGIDLGSEAGINNMKATTLTQGSAIFDQYNAGIGFDA-FELPGGSVAHYVGLEYFDQQYsevyDAQSE 507
Cdd:pfam00593  81 LRLGLRYSSLDGDYTSNSSGLSGAGDYLSDDRLYGLYGLDGDLELSLDLsHDLLLGVELRTAGLDYRRLDD----DAYDP 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  508 AGLIGGSAGNSAAGDRQVWAMFYEAVLPITDDIELNLAARYDDYSDFGDNIA--------------PKAAIRWQALENVV 573
Cdd:pfam00593 157 YDPANPSSSSYSDTTTDSYGLYLQDNIKLTDRLTLTLGLRYDHYSTDGDDGNgggdnfsrsysafsPRLGLVYKPTDNLS 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  574 VRASYSEAFRAPALDQLFAATtfsaedgidkpyceatgtpcSERQFDTYISANKELGPETSQYVNFGVAWDiVDDIGLKV 653
Cdd:pfam00593 237 LYASYSRGFRAPSLGELYGSG--------------------SGGGGGAVAGGNPDLKPETSDNYELGLKYD-DGRLSLSL 295
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  654 DYFNLNIDDVIAQRSITSVMTGIYegtlapsntfyvkrdpasagqaigaasevgTGYSNANTLEISGIDVALNAKFETNI 733
Cdd:pfam00593 296 ALFYIDIKNLITSDPDGPGLGGTV------------------------------YTYTNVGKARIRGVELELSGRLWGLG 345
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  734 GDIGfnwtnsfVLDYTEEVDGGAESRDTSGWNGQPDYKSVFTTNYR--MGDHSLSWNMNYTS-STFYFEDDASKGELDSW 810
Cdd:pfam00593 346 LSGG-------GYTYTDADDDADADDTGNPLPNVPRHTANLGLTYDfpLGGWGARLGARYVGsGERRYGDAANTFKTPGY 418
                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 499957344  811 LIHNISYVYDAGNYGSILLGINNLTDEDPVLSPDGKFENADLYNNYGREYRASYTLK 867
Cdd:pfam00593 419 TLVDLSAGYRLNKNLTLRLGVNNLFDKYYKRYYSSGGGNLGGYPGPGRTFYLGLSYK 475
PRK10064 PRK10064
catecholate siderophore receptor CirA; Provisional
43-868 2.02e-22

catecholate siderophore receptor CirA; Provisional


Pssm-ID: 236646 [Multi-domain]  Cd Length: 663  Bit Score: 103.04  E-value: 2.02e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  43 VTGSRIKRSDLEGASPITTITTEDMKMEGNFTVADALRnsnlnsfgsfsERSG----SSAQSQATINLRGAGSSRTLVLI 118
Cdd:PRK10064  35 VTASAVEQNLKDAPASISVITQEDLQRKPVQNLKDVLK-----------EVPGvqltNEGDNRKGVSIRGLDSSYTLILI 103
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 119 DGKRFPG-SPTLGGASANLNAIPMAAVERIEILTDGASSTYGSDAIAGVVNIIMKKNYQgiefnvgggsrdrdggltske 197
Cdd:PRK10064 104 DGKRVNSrNAVFRHNDFDLNWIPVDAIERIEVVRGPMSSLYGSDALGGVVNIITKKIGQ--------------------- 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 198 fsvvagyqmdkgnitfafdhqdrkgisdadrdftaPWMEDLNGDGVIQAYSETdGWSYYGasvkgpdGIYQPSPLCGDLa 277
Cdd:PRK10064 163 -----------------------------------KWHGTVTVDTTIQEHRDR-GDTYNG-------QFFTSGPLIDGV- 198
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 278 aeygdnvfkqvrgddqfgagsdLCMYAYGNVSYNKASTDRNTVYVDANyeIAEDLEWFgrvmvTQSNSFGRYAPPAANWN 357
Cdd:PRK10064 199 ----------------------LGMKAYGSLAKREKDDPQNSTTTDTG--ETPRIEGF-----TSRDGNVEFAWTPNQNH 249
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 358 NMAAdnphnpfdveakGYfrwvGIGTRDGNVDDYNQDYLTglRGTISALNDAEW-----EVYYHHNIADNKSIGEyylsy 432
Cdd:PRK10064 250 DFTA------------GY----GFDRQDRDSDSLDKNRLE--RQNYSLSHNGRWdygnsELKYYGEKVENKNPGN----- 306
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 433 SGLAYNEANGIDlgseaginnmkattltqgsaifdqynagigfDAFELPGGSVAHYV--GLEYfdqQYSEVYDAqseAGL 510
Cdd:PRK10064 307 SSPITSESNSID-------------------------------GKYTLPLTAINQFLtfGGEW---RHDKLSDA---VNL 349
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 511 IGGSAGNSAAgdRQvWAMFYEAVLPITDDIELNLAARYDDYSDFGDNIAPKAAIRWQALENVVVRASYSEAFRAPALDQL 590
Cdd:PRK10064 350 TGGTSSKTSA--SQ-YALFVEDEWRIFEPLALTTGVRMDDHETYGDHWSPRAYLVYNATDTVTVKGGWATAFKAPSLLQL 426
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 591 FAA-TTFSAEDGidkpyCEATGTPcserqfdtyisankELGPETSQYVNFGVAWD----IVDDIGLKVDYFNLNIDDVIA 665
Cdd:PRK10064 427 SPDwTSNSCRGA-----CKIVGSP--------------DLKPETSESWELGLYYMgeegWLEGVESSVTVFRNDVDDRIS 487
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 666 QRSITSVmtgiyegTLAPSNTFYVKRDPASAGQAIGAASevgtgYSNANTLEISGIDVALNAKFETNIgDIGFNWTNSFV 745
Cdd:PRK10064 488 ISRTSDV-------NAAPGYQNFVGFETNGRGRRVPVFR-----YYNVNKARIQGVETELKIPFNDEW-KLSLNYTYNDG 554
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 746 LDYTEEVDGGAESRDTSGWNGQPDYKSVFTTnyrmgDHSLSWNMNYTSSTFYF-EDDASKGELDSWlihNISYVYDAGNY 824
Cdd:PRK10064 555 RDVSNGENKPLSDLPFHTANGTLDWKPLALE-----DWSFYVSGNYTGQKRADsATAKTPGGYTIW---NTGAAWQVTKD 626
                        810       820       830       840
                 ....*....|....*....|....*....|....*....|....
gi 499957344 825 GSILLGINNLTDEDpvLSPDgKFEnadlYNNYGREYRASYTLKF 868
Cdd:PRK10064 627 VKLRAGVLNLGDKD--LSRD-DYS----YNEDGRRYFMAVDYRF 663
Plug pfam07715
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ...
54-166 1.63e-21

TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.


Pssm-ID: 462243 [Multi-domain]  Cd Length: 107  Bit Score: 90.02  E-value: 1.63e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344   54 EGASPITTITTEDMKMEGNFTVADALRN-SNLNSFGSFSERSGSsaqsqatINLRGAGSSRTLVLIDGKRFPGSptlGGA 132
Cdd:pfam07715   4 DTPGSVSVVTAEDIEDQGATNLADALRGvPGVSVSSGGGGGGSS-------ISIRGFGSNRVLVLVDGVPLNSG---GGG 73
                          90       100       110
                  ....*....|....*....|....*....|....
gi 499957344  133 SANLNAIPMAAVERIEILTDGASSTYGSDAIAGV 166
Cdd:pfam07715  74 SVDLNSIDPEDIERVEVLKGPASALYGSGAIGGV 107
TonB-hemin TIGR01785
TonB-dependent heme/hemoglobin receptor family protein; This model represents the ...
39-868 1.05e-20

TonB-dependent heme/hemoglobin receptor family protein; This model represents the TonB-dependent outer membrane heme/hemoglobin receptor/transporter found in bacteria which live in contact with animals (which contain hemoglobin or other heme-bearing globins) or legumes (which contain leghemoglobin). Some species having hits to this model such as Nostoc, Caulobacter and Chlorobium do not have an obvious source of hemoglobin-like proteins in their biological niche and so the possibility exists that they act on some other substance. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273807 [Multi-domain]  Cd Length: 665  Bit Score: 97.46  E-value: 1.05e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344   39 ERIEVTGSRIKRSDLEGASPITTITTEDMKMEGNFTVADALRN-SNLnsfgSFSERSGSSAQSqatINLRGAGSSRTLVL 117
Cdd:TIGR01785   2 DTVTVTATRTRQVLSEAPASVSVISGEQIESKQANNLADALNTvPGV----DVTGGGRPPGQS---INIRGLQDNRVLVV 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  118 IDGKRFPGspTLGGASANLNAIPMAAVERIEILTDGASSTYGSDAIAGVVNIIMKKNYQGIEFNvgggsrdrdggltsKE 197
Cdd:TIGR01785  75 VDGARQNY--QRGGAHNGSLFVDPELLKRIEIVKGPSSSLYGSGALGGVVAFRTKDAADLLRPG--------------QL 138
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  198 FSVVAGYQMDKGNITFAFDHqdrkgiSDADRdftapwmEDLNGDGVIQAYsetdgwsyygasvkgpdgiyqpsplcgdla 277
Cdd:TIGR01785 139 FGGLAKLSYGSNNNSFGGSV------AVAGR-------LDDNLDALVAAT------------------------------ 175
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  278 aeygdnvfkqVRGDDQFGAGSDLCMYAYGNVSYNKAStdRNTVYVDANYEIAedlewFGrvMVTQSNSfgryappaanwn 357
Cdd:TIGR01785 176 ----------YRDGGNYRNGNKEEATNSAYVQKNLLA--KLGWQLDDAQRLE-----FS--YFTTEGS------------ 224
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  358 nmaADNPHNPFDVEAKGYFRWVGIGTRDGNVDDYNQDYLTGLRGtiSALNDAEWEVYYHHNIADNKSIGEYYLSYSGLAY 437
Cdd:TIGR01785 225 ---LDEAQNSGPGTEYVLGSSSTLLASSTRDRSATLTYNWTPED--NPWLDATASLYYNRTENDNDRSARGVGREEGYQY 299
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  438 NEaNGIDLgseagiNNmkattltqgsaifdqynagigfdAFELPGGSVAHYV-GLEYFDQQYSEVYDAQSEAGLIggsAG 516
Cdd:TIGR01785 300 TT-YGATL------QN-----------------------TSRFDVASWSTLTyGVDWMKDKRRTESFDPNSVTTI---VP 346
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  517 NSAAGDRQVWAMFYEAVLPITDD-IELNLAARYD------------DYSDFGDN-IAPKAAIRWQALENVVVRASYSEAF 582
Cdd:TIGR01785 347 NPPSAKEYFFGLFLQDNIPLLDDrLTLSAGLRYDhyklspkttadtEAVDRSYSrWSPSLGLSYKPVDWLTLYASYSQGF 426
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  583 RAPALDQLFAAttfSAEDGIDKPYCeatgtpcserqfdtyISANKELGPETS--QYVNFGVAWDIV----DDIGLKVDYF 656
Cdd:TIGR01785 427 RAPSIDELYGT---GDHPGTPGGYT---------------FAPNPNLKPETSktWELGANLSFDNLlldnDQLQFKVAYF 488
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  657 NLNIDDVIAQRSitsvmtGIYEGTLAPSNTFyvkrdpasagqaigaasevgTGYSNANTLEISGIDVALNAKFEtnigdi 736
Cdd:TIGR01785 489 YNDVKDFIDLTI------GVTDNVTAGMNNI--------------------TQYVNIDGARIRGIEASASYDAG------ 536
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  737 gfNWTNSFVLDYTEevdgGAESRDTSGWNGQPDYKSVFTTNYRMGDH--SLSWNMNYT---SSTFYFEDDASKG--ELDS 809
Cdd:TIGR01785 537 --LWATGLSYGYTI----GKDQNTNQWLSNIPPLKLVVTVGYRFPDRrlDLGAKAAYYerqSESPTTEDVAANGllTTPG 610
                         810       820       830       840       850       860
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 499957344  810 WLIHNI--SYVYDAGNYGSILLGINNLTDEDPVLSPDgkfenaDLYNNYGREYRASYTLKF 868
Cdd:TIGR01785 611 YTVVDLyaTYQPNAVKGLTVRFGVNNLTDRKYTPAQS------VPGAGPGRNFKGSVKYQF 665
TonB-hemlactrns TIGR01786
TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model ...
41-868 3.59e-18

TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model represents a family of TonB-dependent outer membrane receptor/transporters acting on iron-containing proteins such as hemoglobin, transferrin and lactoferrin. Two subfamily models with a narrower scope are contained within this model, the heme/hemoglobin receptor family protein model (TIGR01785) and the transferrin/lactoferrin receptor family model (TIGR01776). Accessions which score above trusted to this model while not scoring above trusted to the more specific models are most likely to be hemoglobin transporters. Nearly all of the species containing trusted hits to this model have access to hemoglobin, transferrin or lactoferrin or related proteins in their biological niche. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273808 [Multi-domain]  Cd Length: 715  Bit Score: 89.39  E-value: 3.59e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344   41 IEVTGSRIKRSDLEGASPI----TTITTEDMKMEGNFTVADALR-NSNLnsfgSFSERSGSSAQSqatINLRGAGSSRTL 115
Cdd:TIGR01786   3 ITVTATRTADPQRRDLSVTpasvSVISREQLKSQQVRNLRDLLRyEPGV----SVVEGGRGGSQG---INIRGLDKNRVA 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  116 VLIDGKRFPGSPT-LGGASANLNAIPMAAVERIEILTDGASSTYGSDAIAGVVNIIMKknyqgiefnvgggsrdrdgglt 194
Cdd:TIGR01786  76 VLVDGIRQNTSYGgQGSTFYAINSIDPELIKSIEIVKGASSSLYGSGALGGVVAFRTK---------------------- 133
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  195 skefsvvagyqmdkgnitfafdhqdrkgisDAdRDFTAPwmEDLNGDGVIQAYSETDGwsyygasvkgpdgiyqpsplcg 274
Cdd:TIGR01786 134 ------------------------------DA-ADLLKP--GKDLGGLSKLGYSSANN---------------------- 158
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  275 dlaaEYGDNVFKQVRGDDQFGagsdLCMYAYGNV----SYNKASTDRNTVYVDANYEIAEDLEWFGRVMV--TQSNSFG- 347
Cdd:TIGR01786 159 ----RFTQSVAAAGRNDDVDA----LVQATYRRGhelkNGNKANIGNESKRSKPNPSDYKSQSFLAKLGWqlNDAHRLGl 230
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  348 --RYAPPAANWNNMAADNPHNPFDVEAKGYFRWVgIGTRDGNVDDYNQDYltGLRGTISALNDAEWEVYYHHNIADNKSI 425
Cdd:TIGR01786 231 slEYTQTDYDEPEMTNTSYLTKPLGAPLLSSTVV-LGDSKTRDRRTGLDY--ELNPDNSWLDTVKLALDKQYIQLYNYLN 307
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  426 GEYYLSYSGLAYNEANgidlgsEAGINNMKATTLTQGSAIFDQY--NAGIGFDAFELpggsvahyvgleyfDQQYSEVYD 503
Cdd:TIGR01786 308 ATSASDYPGVDKNGRY------KDKYDYYTLGFDTNNKIEFSVHslSLTYGLDRFKD--------------KVSTGDSRR 367
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  504 --AQSEAGLIGGSAGNSAAGDRQVWAmFYEAVLPITDDIELNLAARYDDY---------------SDFGDNIAPKAAIRW 566
Cdd:TIGR01786 368 nlPTAAYNLYGYEGENRPVKGSNFGL-FLQDNIKLGDWLSLSAGLRYDHYktdpkadeskdygaiSKTYSRWSPSLGLTY 446
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  567 QALENVVVRASYSEAFRAPALDQLFaaTTFSAEDGidKPYCeatgtpcserqfdtyISANKELGPETSQYVNFGVAWDIv 646
Cdd:TIGR01786 447 KPTPWLTLYYSYSQGFRAPSFDELY--GTGAHPGG--GPYT---------------FLPNPNLKPETSKNWEIGINLHF- 506
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  647 DDIGLKVDYFNLNIDDVIAQRSitsvmtgiyegtlapsntfyvKRDPASAGQAIGAASEvgTGYSNANTLEISGIDvaLN 726
Cdd:TIGR01786 507 DQLDFKVSYFRNDYKDFIDLGI---------------------GVTAKGNMAQVGSNTI--TNYVNIDNARIRGIE--LS 561
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  727 AKFETNIGDIGFN-WTNSFVLDYTEevdgGAESRDTSGWNGQPDYKSVFTTNYRMGDH--SLSWNMNY--------TSST 795
Cdd:TIGR01786 562 GRYDLGSFFSGPDgWTTTLKYGYTK----GKDSDTNPWLNAITPLKVVLGLGYDHPDEkwGVGLTLTFsgakdavdAYAT 637
                         810       820       830       840       850       860       870
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 499957344  796 FYFEDDASKGEL---DSWLIHNISYVYDAGNYGSILLGINNLTDED--PVLSPDGKFENADLYNNYGREYRASYTLKF 868
Cdd:TIGR01786 638 YYENGEAAKAGPlrtPSYTVVDLYGYYKPNKNLTLRFGVYNLLDRKytTWESARQAGPLATGYTAPGRNYKASVEYKF 715
TonB-siderophor TIGR01783
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ...
56-868 9.43e-17

TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273805 [Multi-domain]  Cd Length: 651  Bit Score: 84.77  E-value: 9.43e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344   56 ASPITTITTEDMKMEGNFTVADALRNSnlnSFGSFSERSGSSaqSQATINLRGAGSSrtlVLIDGKRFPGSPTLggASAN 135
Cdd:TIGR01783   3 PQSVSVITRQELEDQQAGSLSEALQRV---PGVVVGGSGGTT--QFGNITIRGFGLE---VDIDNVYLDGVPLL--SRGN 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  136 LNAIPMAAVERIEILTDGASSTYGSDAIAGVVNIIMKKnyqgiefnvgggsrdrdggLTSKEFSVVAGYQMDKGNITFAF 215
Cdd:TIGR01783  73 LAIVDPAMVERVEVLRGPASLLYGGSAPGGVINIVTKR-------------------PQDEPKGSVTFGAGTRSGYRTAF 133
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  216 DHQDRKGisdADRDFTApwmeDLNGDGviqayseTDGWSYYGASVKGPDGIYqpspLCGDLAAEygDNVFKQVRGDDQFG 295
Cdd:TIGR01783 134 DLGGPLG---ADGTFRG----RLNGAR-------QDGDSFYDGAGEETRLGA----TATDWQLD--DRTLLRLGAYYQKE 193
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  296 AGsdlcMYAYGNVSynkastdrntvyvdanyeiaedlewFGRVMVTQSNSFGRYAPPAANWNnmaadnphnpfdveakgY 375
Cdd:TIGR01783 194 RD----RGGYGGLP-------------------------ASGGTSGRDLSSDRYLGTSSNRN-----------------Y 227
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  376 FRWVGIGTRDGNVDDYNQDYltglrgtisalnDAEWEVYYHHNIADNKSIGEYylsysglAYNEANGiDLGSEAGINNMK 455
Cdd:TIGR01783 228 DDREYLSYGLSLEYQFNDVW------------TGKQNLRYSYFDTDSNQVQAS-------GYSSDGG-LFGRSLTVVNVK 287
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  456 ATtltqgsaiFDQYNAGIGFDaFELpgGSVAHYVGLEYFDQQYSEV--------------YDAQSEAGLIGGSAGNSAAG 521
Cdd:TIGR01783 288 QD--------RVQIDAGLDGE-FET--GPIEHDLLLGVSYGQRTTNrfnntgypsdniysLTATSSARTDIGDSPKDRAL 356
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  522 DRQVWA--MFYEAVLPITDDIELNLAARYD-------------DYSDFGDNIAPKAAIRWQALENVVVRASYSEAFRAPA 586
Cdd:TIGR01783 357 SSTTKAlnGVALQRILLADKWTLTLGGRYDsvdvksnngvagsTGKRDDSQFTPSLGVAYKPTDDWSLYASYAESFKPGG 436
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  587 LDQLFAattfsaedgidkpyceatgtpcserqfdtyISANKELGPETSQYVNFGVAWDIVDDIGLKVDYFNLNIDDVIAQ 666
Cdd:TIGR01783 437 YYPKGA------------------------------GNSGDILEPEKGKNYELGVRYDLGDSLLATAALFRITKDNQLVQ 486
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  667 RSITsvmtgiyegtlapsNTFYvkrdpasagqaigaaseVGTGYSNANTLEISGIDVALnakFETNIgDIGFNWTNSfvl 746
Cdd:TIGR01783 487 DPVN--------------GTFS-----------------VNAGKTRNRGVELEARGYLT---PGLSL-SAGYTYTDA--- 528
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  747 DYTEEVDGGAESRDTSgwnGQPDYKSVFTTNYRMGDHS----LSWNMNYTSStfYFEDDASKGELDSWLIHNISYVYDAG 822
Cdd:TIGR01783 529 EFTEDTNGDTQGNTVP---FVPKHTASLWASYAPPVGDngltLGGGVQYTGK--AYVDGGNTGKVPSYTVVDLSVRYDLT 603
                         810       820       830       840
                  ....*....|....*....|....*....|....*....|....*...
gi 499957344  823 NY--GSILLGINNLTDEDPVLSPDGKFENADLYNNYGREYRASYTLKF 868
Cdd:TIGR01783 604 KKknLTLALNVNNLFDRDYYTSGYRWGPSAYIYPGAPRTVGLSVSYDF 651
PRK13513 PRK13513
ligand-gated channel protein;
43-667 2.31e-16

ligand-gated channel protein;


Pssm-ID: 184104 [Multi-domain]  Cd Length: 659  Bit Score: 83.66  E-value: 2.31e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  43 VTGSRIKRSDLEGASPITTITTEDMKMEGNFTVADALRNSNlnsfGSFSERSGSSAQsqatINLRGAGSSRTLVLIDGKR 122
Cdd:PRK13513  40 VTASGFQQRIQDAPASISVVTREQLENKAYRDVTDALKDVP----GVVVTGGGSTSD----ISIRGMAAKYTLILVDGKR 111
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 123 F------PGSPTLGGASANLNaiPMAAVERIEILTDGASSTYGSDAIAGVVNIIMKKnyqgiefnvgggsrdrdgglTSK 196
Cdd:PRK13513 112 VdtrstrPNSDGSGIEQGWLP--PLAAIERIEVVRGPMSSLYGSDAMGGVINIITRK--------------------VQK 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 197 EfsvvagyqmdkgnitfafdhqdrkgisdadrdftapWMEDLNGDGVIQAySETDGWSYYGAsvkgpdgIYQPSPLCGDL 276
Cdd:PRK13513 170 E------------------------------------WHGSLRADATLQE-DSKSGDIFQTN-------AYASGPLIDGL 205
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 277 aaeYGDNVFKQV--RGDDQFGAGSDLCMYAYGNVSYNKASTDRNTVyvdaNYEIAEDLEwfgrvmvtqsnsfGRYAPP-- 352
Cdd:PRK13513 206 ---LGLKVSGLLshRSEDKIIDGYNEQRMRNGTATFSLTPDDNNEF----DFEIGRYVQ-------------DRNSTPgr 265
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 353 --AANWNNMAADNPHNPFDVEAKGYFrwvgigtRDGNVDDYNQDYLTglrgtisalNDAEWEVYYHHNIADNKSIgeyyl 430
Cdd:PRK13513 266 tlALNGTNSDTQYDRNNYAITHNGYY-------DFGNSTSYIQRDET---------RNPSRQMKSVDTIFNTQTS----- 324
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 431 sysglayneangIDLGSEaginnmkatTLTQGSaifdQYnagigfdafelpggsvahyvgleyfdqQYSEVYDAQSEAgl 510
Cdd:PRK13513 325 ------------FLLDDH---------TLSLGG----QY---------------------------RYEELYDKGNQL-- 350
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 511 igGSAGNSAAGDRQVWAMFYEAVLPITDDIELNLAARYDDYSDFGDNIAPKAAIRWQALENVVVRASYSEAFRAPALDQl 590
Cdd:PRK13513 351 --PSASDLNKLTRWSWALFAEDEWQMTNDFALTGGIRMDQDQNYGTHWTPRLYGVWHLADQWTLKGGVSTGYRSPDLRQ- 427
                        570       580       590       600       610       620       630
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 499957344 591 faattfSAEDgidkpYCEATGTpcseRQFDTYISANKELGPETSQYVNFGVAWDIVDDIGLKVDYFNLNIDDVIAQR 667
Cdd:PRK13513 428 ------ATDN-----WGQLTGG----GGLPALILGNSDLKPEKSISQEIGILWDNQENLNASVTLFNTDFKDKITEV 489
PRK13486 PRK13486
TonB-dependent receptor;
43-838 2.34e-16

TonB-dependent receptor;


Pssm-ID: 139606 [Multi-domain]  Cd Length: 696  Bit Score: 83.53  E-value: 2.34e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  43 VTGSRIKRSDLEGASPITTITTEDMKMEGNFTVADALRnsnlnSFGSFSERSGSSAQSQATINLRGAGSSRTLVLIDGKR 122
Cdd:PRK13486  30 VSASGYEKKLTNAAASVSVISQEELQSSQYHDLAEALR-----SVEGVDVESGTGKTGGLEISIRGMPASYTLILIDGVR 104
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 123 FPGSPTL---GGASANLNAIP-MAAVERIEILTDGASSTYGSDAIAGVVNIIMKKNyqgiefnvgggsrdrdggltskef 198
Cdd:PRK13486 105 QGGSSDVtpnGFSAMNTGFMPpLAAIERIEVIRGPMSTLYGSDAMGGVVNIITRKN------------------------ 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 199 svvagyqmdkgnitfafdhqdrkgisdADRdftapWMEDLNGDGVIQaysETDGWsyyGASVKGpdGIYQPSPLCgdlaa 278
Cdd:PRK13486 161 ---------------------------ADK-----WLSSVNAGLNLQ---ESNKW---GNSSQF--NFWSSGPLV----- 195
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 279 eyGDNVFKQVRGDDQFGAGSDLcmyaygnVSYNKASTDRNTVYVDA-NYEIAEDLEWfgrvMVTQSNSFgryappaanWN 357
Cdd:PRK13486 196 --DDSVSLQVRGSTQQRQGSSV-------TSLSDTAATRIPYPTESqNYNLGARLDW----KASEQDVL---------WF 253
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 358 NMaaDNPHNPFDveakgyfrwvgigTRDGNVDDYNQDYLTGLR--------GTISALNDAEWEVYYHHNIADNKSigeYY 429
Cdd:PRK13486 254 DM--DTTRQRYD-------------NRDGQLGSLTGGYDRTLRyernkisaGYDHTFTFGTWKSYLNWNETENKG---RE 315
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 430 LSYSGLAYNEAngidlGSEAGINNMKATTLTQGSAIFDQYnagigfdafelpGGSVAHYVGLEYfdqqysevYDAQSEAG 509
Cdd:PRK13486 316 LVRSVLKRDKW-----GLAGQPRELKESNLILNSLLLTPL------------GESHLVTVGGEF--------QSSSMKDG 370
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 510 LIGGSAGNSAagDRQVWAMFYEAVLPITDDIELNLAARYDDYSDFGDNIAPKAAIRWQALENVVVRASYSEAFRAPALDQ 589
Cdd:PRK13486 371 VVLASTGETF--RQKSWSVFAEDEWHLTDALALTAGSRYEHHEQFGGHFSPRAYLVWDVADAWTLKGGVTTGYKAPRMGQ 448
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 590 LFaattfsaedgidkpyceaTGTPCSERQFDTYISANKELGPETSQYVNFGVAWDivddiglKVDYFNLNIDDVIAQRSI 669
Cdd:PRK13486 449 LH------------------KGISGVSGQGKTNLLGNPDLKPEESVSYEAGVYYD-------NPAGLNANVTGFMTDFSN 503
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 670 TSVMTGIYEGTLAPSNTfyvkrdpasagqaiGAASEVGTGYSNANTLEISGIDVALNakfetnigdigFNWTNSfvldyt 749
Cdd:PRK13486 504 KIVSYSINDNTNSYVNS--------------GKARLHGVEFAGTLPLWSEDVTLSLN-----------YTWTRS------ 552
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 750 EEVDGGAESRDTS-----------GWNGQPDYKSVFTTNYRmgDHSLSWNMNYTS-STFYFEDDASKGE-LDSWLIHNIS 816
Cdd:PRK13486 553 EQRDGDNKGAPLSytpehmvnaklNWQITEEVASWLGARYR--GKTPRFTQNYSSlSAVQKKVYDEKGEyLKAWTVVDAG 630
                        810       820
                 ....*....|....*....|..
gi 499957344 817 YVYDAGNYGSILLGINNLTDED 838
Cdd:PRK13486 631 LSWKMTDALTLNAAVNNLLNKD 652
PRK13483 PRK13483
ligand-gated channel protein;
32-868 5.52e-16

ligand-gated channel protein;


Pssm-ID: 184080 [Multi-domain]  Cd Length: 660  Bit Score: 82.52  E-value: 5.52e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  32 DEDGAKVERIEVTGSRIKRSDLEGASPITTITTEDMKMEGNFTVADALRNSNlnsfGSFSERSGSSAQsqatINLRGAGS 111
Cdd:PRK13483  27 AAPDKTMETVVVTASGYEQQIRDAPASISVITREDLENRFYRDLTDALLDVP----GVVVTGGGDRTD----ISLRGMGS 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 112 SRTLVLIDGKR------FPGSPTLGGASANLNaiPMAAVERIEILTDGASSTYGSDAIAGVVNIIMKKnyqgiefnvggg 185
Cdd:PRK13483  99 QYTLILVDGKRqssretRPNSDGPGVEQAWTP--PLAAIERIEVIRGPMSSLYGSDAIGGVINIITRK------------ 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 186 srdrdgglTSKEfsvvagyqmdkgnitfafdhqdrkgisdadrdftapWMEDLNGDGVIQAYSETdGWSYYGasvkgpdG 265
Cdd:PRK13483 165 --------VPNE------------------------------------WQGEVRLDTTLQENSDS-GNVYQA-------N 192
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 266 IYQPSPLCGDLaaeYGDNVFKQV--RGDDQFGAGsdlcmyaYGNVSyNKASTDRNTVYVDANYEIAEDLewfGRVMVTQS 343
Cdd:PRK13483 193 FFVNGPLIKDL---LGLQLYGQYtqREEDDIEGG-------YRDKD-ARSLTAKLALTPNEDHDIMLEV---GTSNQERD 258
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 344 NSFGRYAPPAANWnnmaadnphnpfdvEAKGyfrwvgigtRDGNVDDYNQDYltgLRGTISALNDAEWEV-----YYHHN 418
Cdd:PRK13483 259 STVGKTVAPLAPG--------------ESCG---------RRGCPESSTTEY---ERSTVSLSHTGRWDFgtsdtYIQHE 312
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 419 IADNKSigeyylsysglayneangidlgSEAGINNMKATTltqgsaifdQYNAGIGfdafelpggsVAHY--VGLEYFDQ 496
Cdd:PRK13483 313 EFDNKS----------------------REMKIKNTDFQS---------SLVAPLG----------QEHTltFGAAYNHQ 351
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 497 QYSEvydaqseagliggSAGNSAAG----DRQVWAMFYEAVLPITDDIELNLAARYDDYSDFGDNIAPKAAIRWQALENV 572
Cdd:PRK13483 352 DLTD-------------ETSNQISDltdiSRTQWAVFSEDEWRIADDFALTGGLRLDHDENFGGHVSPRVYGVWNLAPSW 418
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 573 VVRASYSEAFRAPALDQLFAATTFSAEDGidkpyceatgtpcserqfdtYISANKELGPETSQYVNFGVAWDIVDDIGLK 652
Cdd:PRK13483 419 TVKGGVSTGFRAPSLRQTTPDWGQVSRGG--------------------NIYGNPDLKPETSLNKELGLYYDLGSGLTAS 478
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 653 VDYFNLNIDDviaqrSITSVMTGIYEGTLAPsNTFyvKRDPasagqaigaasevgTGYSNANTLEISGIDVALNAKFETN 732
Cdd:PRK13483 479 LTVFYNEFKD-----KITRVACPATQCTDGP-NQF--GADP--------------TTYVNIDEAVTQGVEASLSYPITST 536
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 733 IGDIGfNWTnsfvldYTeevdggaESRDTSG-WNGQ-----PDYKSVFTTNYRMGDHSLSW-NMNYTSStfyfEDDASKG 805
Cdd:PRK13483 537 LSLSG-NYT------YT-------DSEQKSGaYKGSplnqlPKHLFQASLNWEPTDRLNSWaRVNYRGE----ESQPTTG 598
                        810       820       830       840       850       860       870
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 806 ELDSWLIHNiSYVY-DAG-NYG-----SILLGINNLTDEDPVLSPDGKFENadlynnyGREYRASYTLKF 868
Cdd:PRK13483 599 PSSSSFIAP-SYTFlDLGaNYQltdnlKLSAGIYNLFDKEINYEEYGYVED-------GRRYWLGMTYSF 660
FecA COG4772
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
33-838 7.06e-16

Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];


Pssm-ID: 443804 [Multi-domain]  Cd Length: 681  Bit Score: 81.90  E-value: 7.06e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  33 EDGAKVERIEVTGSRIKRSDLE---GAspITTITTEDMKMEGNFTVADALRNS-NLNsfgsFSERSGSSAQSQatINLRG 108
Cdd:COG4772   18 EAATTLETVVVTGSRAAEARLKdvpGS--VSVVDREELENQAATSLREVLRRVpGVN----VQEEDGFGLRPN--IGIRG 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 109 AG---SSRTLVLIDGkrFPGSPTLGGASANLNAIPMAAVERIEILTDGASSTYGSDAIAGVVNIIMKKNYQGIEFNVGGG 185
Cdd:COG4772   90 LGprrSRGITLLEDG--IPIAPAPYGDPAAYYFPDLERMERIEVLRGAAALRYGPQTVGGAINFVTRTIPTAFGGELRVT 167
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 186 SRDRDggltSKEFSVVAGYQMDKGNITFAFDHQDrkgiSDADRDFTAPWMEDLNGDGVIQAySETDGWSYYGASVKGPDG 265
Cdd:COG4772  168 GGSFG----YRRTHASVGGTVGNFGYLVEYSRKR----GDGFRDNSGFDINDFNAKLGYRL-SDRQELTLKFQYYDEDAN 238
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 266 IYqpsplcGDL-AAEYGDNVFKQVRGDDQFgagsdlcmyaygnvsynkaSTDRNTVYVDANYEIAEDLEWFGRVMVTQSN 344
Cdd:COG4772  239 TP------GGLtDAQFDADPRQSYRPADQF-------------------DTRRTQLSLRYEHQLSDNTTLTTTAYYNDFS 293
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 345 SFGRYAPPAANWNNMAADNPHNPFDveakgyFRWVGIGTR---DGNVDDYNQDYLTGLRgtisalndaewevYYHHNIAD 421
Cdd:COG4772  294 RNWYIRQNTADPNTPGLGLRGNPRG------YRSYGIEPRlthRFELGGVPHTLEVGLR-------------YHREEEDR 354
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 422 NKSIGEYYLSYSGLAYNEANgidlgseagINNMKATtltqgsAIFDQYNAGIGfDAFEL-PGgsvahyVGLEYFDQQYSE 500
Cdd:COG4772  355 KQYVNTYGQGRSGAGLRRDR---------RFSADAL------AAYAQNRFELT-GRLTLtPG------LRYEHIRRDRTD 412
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 501 VYDAQSeagliggSAGNSAAGDRQVWamfyeavlpitddielnlaaryddysdfgdniAPKAAIRWQALENVVVRASYSE 580
Cdd:COG4772  413 RYSTRT-------GGDDSGSNSYSEF--------------------------------LPGLGLLYQLTDNLQLYANVSR 453
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 581 AFRAPALDQLFAATTFsaedgidkpyceatgtpcserqfdtyisaNKELGPETSQYVNFGVAWDIVDDIGLKVDYFNLNI 660
Cdd:COG4772  454 GFEPPTFGDLAYGNGG-----------------------------NPDLKPEKSWNYELGTRGRIGNGLSAEVALFYIDY 504
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 661 DDVIAQRSitsvmtgiyegtlapsntfyvkrdpasagqaigAASEVGTGYSNANTLEISGIDVALNAKFETNiGDIGFNW 740
Cdd:COG4772  505 DNELGSCS---------------------------------AAGGDRSTFTNAGETRHQGLELALDYDLLKG-GGLGLPL 550
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 741 TNSFvlDYTEevdggAESRDTSGWN-------GQPDYKSVFTTNYRMGDHSLSWNMNYTSSTFY----FEDDASKGELDS 809
Cdd:COG4772  551 FAAY--TYTD-----AEFTSDFGPVfagnrlpYVPRHQLTAGLGYEHGGWTANLNGRYVSEQFTdaanTVADGSFGKIPS 623
                        810       820
                 ....*....|....*....|....*....
gi 499957344 810 WLIHNISYVYDAGNYGSILLGINNLTDED 838
Cdd:COG4772  624 YTVLDLSASYDFGKNLSLFAGVNNLFDKR 652
TonB-B12 TIGR01779
TonB-dependent vitamin B12 receptor; This model represents the TonB-dependent outer membrane ...
43-293 1.49e-15

TonB-dependent vitamin B12 receptor; This model represents the TonB-dependent outer membrane receptor found in gamma proteobacteria responsible for translocating the cobalt-containing vitamin B12 (cobalamin). [Transport and binding proteins, Other, Transport and binding proteins, Porins]


Pssm-ID: 273802 [Multi-domain]  Cd Length: 614  Bit Score: 80.68  E-value: 1.49e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344   43 VTGSRIKRSDLEGASPITTITTEDMKMEGNFTVADALRNSNlnsfGSFSERSGSSAQSqATINLRGAGSSRTLVLIDGKR 122
Cdd:TIGR01779  33 VTANRFAQTASQTLAPVTIITRQDIERTQAKSLPELLRRLP----GVSIAQNGGRGQN-TSLFLRGTESDHVLVLIDGIR 107
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  123 FpGSPTLGGASanLNAIPMAAVERIEILTDGASSTYGSDAIAGVVNIIMKKNYQGIEFNVgggsRDRDGGLTSKEFSVVA 202
Cdd:TIGR01779 108 F-GSAAAGAAD--FQQLPVELVERIEYVRGPRSSLYGSEAIGGVINIITRRRSGGQGTTL----SAGLGSLDYQEYSIAS 180
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  203 GYQM-DKGNITFAFDHQDRKGIS---------DADRD-FTApwmEDLNGDGViqaYSETDGWSYYGaSVKGPDGIYQPSp 271
Cdd:TIGR01779 181 GVAIgENGWYSVALGTESTKGINvrpggpgvyDPDRDgFRS---DSLLLGGG---HRFDESWSLFV-NALRYENRNDYD- 252
                         250       260
                  ....*....|....*....|..
gi 499957344  272 lcgdlAAEYGDNVFKQVRGDDQ 293
Cdd:TIGR01779 253 -----NYSFGTRLYKEAEKGDQ 269
PRK13484 PRK13484
IreA family TonB-dependent siderophore receptor;
37-662 2.16e-13

IreA family TonB-dependent siderophore receptor;


Pssm-ID: 139605 [Multi-domain]  Cd Length: 682  Bit Score: 73.89  E-value: 2.16e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  37 KVERIEVTGSRIKRSDLEGASPITTITTEDMKMEGNFTVADALRNSNlnsfgSFSERSGSSAQSqatINLRGAGSSRTLV 116
Cdd:PRK13484  29 KEDTLVVTASGFTQQLRNAPASVSVITSEQLQKKPVSDLVDAVKDVE-----GISITGGNEKPD---ISIRGLSGDYTLI 100
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 117 LIDGKRFPGSPTLGGASANLNA---IPMAAVERIEILTDGASSTYGSDAIAGVVNIIMKKnyqgiefnvgggsrdrdggL 193
Cdd:PRK13484 101 LVDGRRQSGRESRPNGSGGFEAgfiPPVEAIERIEVIRGPMSSLYGSDAIGGVINIITKP-------------------V 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 194 TSKEFSVVAGYqmdKGNITfafDHQDRKGISDADRDFTAPWMEDLNGdgvIQAYsetdGWSYYGASvkgpDGIYQPSPlc 273
Cdd:PRK13484 162 NNQTWDGVLGL---GGIIQ---EHGKFGNSTTNDFYLSGPLIKDKLG---LQLY----GGMNYRKE----DSISQGTP-- 222
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 274 gdlaaeYGDNvfKQVRGDDQFgagsdlcmyaygnvsynkASTDRNTVYVDANYEIAEDLEWFGRVMVTQSNSFGRYAPpa 353
Cdd:PRK13484 223 ------AKDN--KNITATLQF------------------TPTESQKFVFEYGKNNQVHTLTPGESLDAWTMRGNLKQP-- 274
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 354 anwNNM-AADNPHNpfdveakgyfRWVGIGTRDGNVddynqdyltgLRGTISalndaeweVYYHHNIADNKSIGEyylsy 432
Cdd:PRK13484 275 ---NSKrETHNSRS----------HWVAAWNAQGEI----------LHPEIA--------VYQEKVIREVKSGKK----- 318
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 433 sglayNEANGIDLGSEAGINNMKATtltqgsaIFDQynagiGFDAFeLPGGSVAhyVGLEYfdqQYSEVYDAQSeaglIG 512
Cdd:PRK13484 319 -----DKYNHWDLNYESRKPEITNT-------IIDA-----KVTAF-LPENVLT--IGGQF---QHAELRDDSA----TG 371
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 513 GSAGNSAAGDRQVWAMFYEAVLPITDDIELNLAARYDDYSDFGDNIAPKAAIRWQALENVVVRASYSEAFRAPALDQLFA 592
Cdd:PRK13484 372 KKTTETQSVSIKQKAVFIENEYAATDSLALTGGLRLDNHEIYGSYWNPRLYAVYNLTDNLTLKGGIAKAFRAPSIREVSP 451
                        570       580       590       600       610       620       630
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 593 ATTFSAEDGIDKPYceatgtpcserqfdtyisANKELGPETSQYVNFGVAWDIVDDIGLKVDYFNLNIDD 662
Cdd:PRK13484 452 GFGTLTQGGASIMY------------------GNRDLKPETSVTEEIGIIYSNDSGFSASATLFNTDFKN 503
btuB PRK10641
TonB-dependent vitamin B12 receptor BtuB;
43-182 6.10e-13

TonB-dependent vitamin B12 receptor BtuB;


Pssm-ID: 236730 [Multi-domain]  Cd Length: 614  Bit Score: 72.33  E-value: 6.10e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  43 VTGSRIKRSDLEGASPITTITTEDMKMEGNFTVADALRNSNlnsfGSFSERSGSSAQSqATINLRGAGSSRTLVLIDGKR 122
Cdd:PRK10641  30 VTANRFQQPVSTVLAPTTVVTRDDIDRWQSKSVNDVLRRLP----GVDIAQNGGLGQL-SSLFIRGTNSSHVLVLIDGVR 104
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 123 FpGSPTLGGaSANLNAIPMAAVERIEILTDGASSTYGSDAIAGVVNIIMKKNYQGIEFNV 182
Cdd:PRK10641 105 L-NQAGISG-SADLSQIPISLVQRIEYIRGPRSAVYGSDAIGGVVNIITTRDKPGTTLSA 162
PRK13528 PRK13528
outer membrane receptor FepA; Provisional
32-639 5.35e-12

outer membrane receptor FepA; Provisional


Pssm-ID: 237413 [Multi-domain]  Cd Length: 727  Bit Score: 69.79  E-value: 5.35e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  32 DEDGAKVERIEVTGSRikrsDLEGASPITTITTEDMKMEGNFT-VADALRNS---NLNSfGSFSERSGSSAQsqatINLR 107
Cdd:PRK13528  30 DDDNGETMVVEATAEQ----ELKQQPGVSIITAEDIKKRPPVNdLSDIIRKMpgvNLTG-NSASGTRGNNRQ----IDIR 100
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 108 GAGSSRTLVLIDGK--------RFP--GSPTLGGASanlNAIPMAAVERIEILTDGASSTYGSDAIAGVVNIIMKKNyqg 177
Cdd:PRK13528 101 GMGPENTLILIDGVpvtsrnsvRYSwrGERDTRGDT---NWVPPEMVERIEVIRGPAAARYGSGAAGGVVNIITKRP--- 174
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 178 iefnvgggsrdrdgglTSKEfsvvagyqmdKGNITFafdhqdrkgisdadrdFTApwmedlngdgviQAYSETDGWSY-Y 256
Cdd:PRK13528 175 ----------------TNDW----------HGSLSL----------------YTN------------QPESSKEGATRrA 200
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 257 GASVKGpdgiyqpsPLCGDlaaeygdnvfkqvrgddqfgagsDLCMYAYGNvsYNKASTDRNTVYVDANYEIAEdlewfG 336
Cdd:PRK13528 201 NFSLSG--------PLAGD-----------------------ALTMRLYGN--LNKTDADSWDINSSAGTKNAA-----G 242
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 337 RVMVTQS--NSFGRYAPpaanwnnmaadNPHNPFDVEAkGYfrwvgigTRDGNVddYNQDYLTGLRGTIS---ALNDAEW 411
Cdd:PRK13528 243 REGVRNKdiNGVLSWKM-----------TPQQILDFEA-GY-------SRQGNI--YAGDTQNSNSSAVTeslAKSGKET 301
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 412 EVYYHHNIA-DNKSIGEYYLSYSGLAYNEANGIDL--GSEAGINNMKATTLTQGSAIFDQYNAGIGFD-AFELPGGSVAh 487
Cdd:PRK13528 302 NRLYRQNYGlTHNGIWDWGQSRLGFYYEKTNNTRMneGLAGGGEGRITADQTFTTSRLESYRTSGELNvPLNWLFEQTL- 380
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 488 YVGLEYFDQQYSEVYDAQSE--AGLIGGSAGnsAAGDR------QVWAMFYEAVLPITDDIELNLAARYDDYSDFGDNIA 559
Cdd:PRK13528 381 TVGAEWNRDELNDPSSTSLTvkDGDIGGISG--SAADRssknksEISALYVEDNIEPVPGTNLIPGLRFDYHSEFGSNWS 458
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 560 PKAAIRWQALENVVVRASYSEAFRAPALDQlfaattfSAEDGIdkPYCEATGTPCSERQFDTYISANKELGPETSqyVNF 639
Cdd:PRK13528 459 PSLNLSQELGDYFKVKAGIARAFKAPNLYQ-------SSEGYL--LYSRGNGCPKDITSGGCYLVGNKNLDPEIS--VNK 527
Fiu COG4774
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
59-868 2.50e-11

Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];


Pssm-ID: 443806 [Multi-domain]  Cd Length: 639  Bit Score: 67.21  E-value: 2.50e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  59 ITTITTEDMKMEGNFTVADALRN----SNLNSFGSFSERsgssaqsqatINLRGAgSSRTLVLIDGKRFPGSptlggasa 134
Cdd:COG4774   13 VTVVTRELIEDQGATSLADALRNvpgvTFGAGEGGNGDS----------FSIRGF-SASGDIYVDGLRDPGQ-------- 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 135 nlNAIPMAAVERIEILTDGASSTYGSDAIAGVVNIIMKKnyqgiefnvgggsrdrdggltskefsvvaGYQMDKGNITFA 214
Cdd:COG4774   74 --YRRDTFNLERVEVLKGPASVLYGRGSPGGVINLVTKR-----------------------------PTDEPFTEVTLT 122
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 215 FdhqdrkgisdadrdftapwmedlngdgviqaysetDGWSYYGASVkgpdgiyqpsplcgDLAAEYGDNVFkqVRgddqF 294
Cdd:COG4774  123 Y-----------------------------------GSDGQRRATL--------------DVNGPLGDDLA--YR----L 147
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 295 GAgsdlcMYAYGNVSYNKASTDRNTVYVDANYEIAEDLEWFGRVMVTQSNSFGRYAPPAANWNnmaadnphNPFDVEAKG 374
Cdd:COG4774  148 NG-----MYRDSDSYRDGVDNDRWGIAPSLTWRLGDRTRLTLDYEYQDDDRTPDYGVPAVANG--------RPVDVDRST 214
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 375 YFrwvgigtrdGNVDDYN--QDYLTGLRGTisalndaewevyyhHNIADNKSIgeyylsYSGLAYNEANGIDLGSEAGIN 452
Cdd:COG4774  215 FY---------GQPDDYSdsETDSATLRLE--------------HDFNDNWTL------RNALRYSDYDRDYRNTYPTGG 265
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 453 NmKATTLTQGSAIFDQYNAGIGFDA---FELPGGSVAH--YVGLEYFDQQYSE-------------VYDAQSEAGLIGGS 514
Cdd:COG4774  266 N-ATGTVTRSAYRRDQDNDTLSNQTdltGKFDTGGVKHtlLAGVEYSREDSDNarysgggtaptvnLYNPVYGAPVTGPT 344
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 515 AGNSAA-GDRQVWAMFYEAVLPITDDIELNLAARYDDY-SDFGDNIA-------------PKAAIRWQALENVVVRASYS 579
Cdd:COG4774  345 LGGADNdSRTDTTGLYLQDTISLTDRWSLLAGLRYDRFdTDYTDRTTgattssyddsafsPRAGLVYKPTPNLSLYASYS 424
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 580 EAFRAPALDQLFAAttfsaedgidkpyceatgtpcserqfdtyisANKELGPETSQYVNFGVAWDIVDD-IGLKVDYFNL 658
Cdd:COG4774  425 TSFNPGGGAPSLSN-------------------------------AGQALDPEKSRQYEVGVKWDLLDGrLSLTAALFRI 473
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 659 NIDDVIAQrsitsvmtgiyegtlapsntfyvkrDPASAGQaigaasevgtgYSNANTLEISGIDVALNAKFETN---IGd 735
Cdd:COG4774  474 EKTNVRTT-------------------------DPANPGV-----------YVQTGEQRSRGVELEATGELTPGwsvLA- 516
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344 736 iGFNWTNSFVLDYTEEVDGGAESRDTSGWNGqpdykSVFTTnYRMGDHSLSWN--MNYTSSTFYfeDDASKGELDSWLIH 813
Cdd:COG4774  517 -GYTYLDAEITKSANAANVGNRLPNVPRHSA-----SLWTT-YDLPLPGLTLGggVRYVGSRYA--DAANTVKLPSYTRF 587
                        810       820       830       840       850
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 499957344 814 NISYVYDAGNYGSILLGINNLTDEDPVLSPDGkfeNADLYNNYGREYRASYTLKF 868
Cdd:COG4774  588 DAGASYRLNKNLTLRLNVNNLTDKRYYASAYG---SGYVTPGAPRTVLLSASYRF 639
PRK13524 PRK13524
FepA family TonB-dependent siderophore receptor;
1-173 1.22e-10

FepA family TonB-dependent siderophore receptor;


Pssm-ID: 237410 [Multi-domain]  Cd Length: 744  Bit Score: 65.44  E-value: 1.22e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344   1 MHKNVLAKSVRLALISGAAAAAFASPAVFAADEDGAKVERIEVTGSRIKRSDLeGASpitTITTEDMKME--GNfTVADA 78
Cdd:PRK13524   1 MNKKIHSLALLVNLGIYGVAQAAEAEDAKTDDTPASHEDTIVVTAAEQNLQAP-GVS---TITAEDIRKRppAN-DVSEI 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  79 LRNS---NLnsfgsfserSGSSAQSQ----ATINLRGAGSSRTLVLIDGKRFPG--SPTLGGAS-----ANLNAIPMAAV 144
Cdd:PRK13524  76 IRTMpgvNL---------TGNSTSGQrgnnRQIDIRGMGPENTLILIDGKPVSSrnSVRYGWRGerdtrGDTNWVPPEMI 146
                        170       180
                 ....*....|....*....|....*....
gi 499957344 145 ERIEILTDGASSTYGSDAIAGVVNIIMKK 173
Cdd:PRK13524 147 ERIEVLRGPAAARYGNGAAGGVVNIITKK 175
FhuE COG4773
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ...
44-173 2.46e-08

Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];


Pssm-ID: 443805 [Multi-domain]  Cd Length: 692  Bit Score: 57.60  E-value: 2.46e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  44 TGSRIKRSDLEGASPITTITTEDMKMEGNFTVADALRNSNlnsfGSFSERSGSSAQSQatINLRGAGSSRtlVLIDGkrf 123
Cdd:COG4773   54 TATKLDTPLRETPQSVSVVTRQLIEDQGATTLDDALRNVP----GVTVSSYDGGGRDS--FSIRGFSIDN--YLRDG--- 122
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 499957344 124 pgsptLGGASANLNAIPMAAVERIEILTdGASST-YGSDAIAGVVNIIMKK 173
Cdd:COG4773  123 -----LPLGGFGGGQPDTANLERVEVLK-GPAGLlYGAGSPGGLVNLVTKR 167
OMP_RagA_SusC TIGR04056
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade ...
33-173 1.48e-05

TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 274948 [Multi-domain]  Cd Length: 981  Bit Score: 48.74  E-value: 1.48e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344   33 EDGAKVERIEVTGSRI-KRSDLEGAspITTITTEDMKM--EGNFTVADALRNSNLNSFGSFSERSGSsaqsqATINLRGA 109
Cdd:TIGR04056  73 EDTQELDEVVVVGYGTqKKKSLTGA--VSTVKAKELKKvpVSNLSNALQGKVAGVIITQSSGEPGGD-----AEIWIRGI 145
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  110 GS----SRTLVLIDGkrFPGSPtlggasaNLNAIPMAAVERIEILTDgASST--YGSDAIAGVVNIIMKK 173
Cdd:TIGR04056 146 SSfggnNSPLYVIDG--VPRDN-------GLSDLNPEDIESISVLKD-ASATaiYGSRGANGVILITTKR 205
TonB-Xanth-Caul TIGR01782
TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane ...
38-682 2.28e-05

TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane receptors which are found mainly in Xanthomonas and Caulobacter. These appear to represent the expansion of a paralogous family in that the 22 X. axonopodis (21 in X. campestris) and 18 C. crescentus sequences are more closely related to each other than any of the many TonB-dependent receptors found in other species. In fact, the Crescentus and Xanthomonas sequences are inseparable on a phylogenetic tree using a PAM-weighted neighbor-joining method, indicating that one of the two genuses may have acquired this set of receptors from the other. The mechanism by which this family is shared between Xanthomonas, a gamma proteobacterial plant pathogen and Caulobacter, an alpha proteobacterial aquatic organism is unclear. [Transport and binding proteins, Porins]


Pssm-ID: 273804 [Multi-domain]  Cd Length: 845  Bit Score: 48.10  E-value: 2.28e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344   38 VERIEVTGSR--------IKRSDlegASPITTITTEDMKMEGNFTVADALRnsnlnsfgsfseR----SGSSAQSQA-TI 104
Cdd:TIGR01782   1 LDAVQVTGQRaslekaidAKRDA---DSVVDVISAEDIGKLPDVNVAEALQ------------RvpgvSIERDQGEGrYV 65
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  105 NLRGAGSSRTLVLIDGKRFPgSPTLGGASANLNAIPMAAVERIEILTdgaSSTYG--SDAIAGVVNIIMKK--NYQGIEF 180
Cdd:TIGR01782  66 SVRGLGPSYNRTTLNGRTIA-STDSGGRAFSLDLLPSELVSGVEVYK---TPTADmdEGGIGGTVDLRTRSpfDYDGRTL 141
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  181 NVGGGSRDRDGGLTSKEFSVVAGYQMDKGN-----ITFAFDHQDRKGISDadrdftapwmedlngdgviqaYSETDGWSY 255
Cdd:TIGR01782 142 SGSAQGGYNDLAGKDKPGPRGAASYSWTFGdgqfgVLLSASYQKRDFAED---------------------NVETENWGT 200
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  256 YGASVKGPDGIYQPSplcgdlAAEYGDNVFKQVR----GDDQFGAGSDLCMYAygNVSYNKASTDRNTVYVDANyeiaed 331
Cdd:TIGR01782 201 YTSADGGAQGLYFPR------GVRYRSYRNDRERkgvnGSLQWRPSDALELYL--DTLYSKYDDDETRQQIEFR------ 266
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  332 leWFGRVMVTQSNSFG--RYAPPAANWNNMAADNPHNPFDVEAK---------------------GY--------FRWVG 380
Cdd:TIGR01782 267 --TLNGGSTVITSNQTatSGALVQGTVANLQILVEARYNEEKETttsltlggewtgdrwtldgdlGYskatrdrpDRVTR 344
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  381 IGTRDGNVDDYNQDYLTGLRGTISALNDAEWEVY-------YHHNIADNKSIGEYYLSYSGLAYneaNGIDLGSEAGInn 453
Cdd:TIGR01782 345 FFTAPTPGYDFDYRGGPTLTLGTPADGDDASNYTnpangelRRTQISYQKAEDSEDAAQLDATF---DGPFTSLKFGV-- 419
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  454 mKATTLTQGSAIFDQYNAGIG---FDAFELPGGSVAHYVGLEYFDQQYSEVY---------DAQSEAGLIGGSAGNSAAG 521
Cdd:TIGR01782 420 -RYRRRDKTNRGSRYRRSIIGatgASGLAGVPSDLAGAGLDGGLGGPLTGWDpadldaflnAARGDAAGGGTYTYASTAP 498
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  522 D--------RQVWAMfyeAVLPITDDIELNLAARYDD--------------------YSDFG-----DNIAPKAAIRWQA 568
Cdd:TIGR01782 499 NtytvtedtTAAYAM---ANFDTGLRLRGNVGVRYERtdqtsdgwqsqpaangtgsvLVPVSadrdyTDVLPSLNLAYDL 575
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499957344  569 LENVVVRASYSEAFRAPALDQLFAATTFSaEDGIDKPYceaTGTpcserqfdtyiSANKELGPETSQYVNFGVAWDIVDD 648
Cdd:TIGR01782 576 TDDLVLRFAASKTITRPDFGDLAANTSLS-DDGTGGTV---TVS-----------GGNPDLKPYESDNLDLSLEWYFGPG 640
                         730       740       750
                  ....*....|....*....|....*....|....
gi 499957344  649 IGLKVDYFNLNIDDVIAQRSITSVMTGIYEGTLA 682
Cdd:TIGR01782 641 GLLSAAVFYKDIKNFIVTTTSTETNDGGGGLVVA 674
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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