|
Name |
Accession |
Description |
Interval |
E-value |
| recA |
PRK09354 |
recombinase A; Provisional |
31-348 |
1.12e-166 |
|
recombinase A; Provisional
Pssm-ID: 236476 [Multi-domain] Cd Length: 349 Bit Score: 468.50 E-value: 1.12e-166
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 31 DVLKLLQQKFGKTNIYLNEKDELKDLEAISTGSIKLDHALGTDGFIKGRIVEIYGNESCGKTTLALSTIKQAIDRNMRVA 110
Cdd:PRK09354 13 AALKQIEKQFGKGSIMRLGDDAAMDVEVISTGSLALDIALGIGGLPRGRIVEIYGPESSGKTTLALHAIAEAQKAGGTAA 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 111 FIDAEHALDLRYVKRLGIDLTKLIIARPDYGEQGFEIIKSLIKTELIDLIVVDSVAALVPKVEIEGKMEDQTMGTHARMM 190
Cdd:PRK09354 93 FIDAEHALDPVYAKKLGVDIDNLLVSQPDTGEQALEIADTLVRSGAVDLIVVDSVAALVPKAEIEGEMGDSHVGLQARLM 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 191 SRGLSRIQPLLAKHNVSVIFINQLREKVGIMFGNPEVTTGGKALKFYSSTRLELRRAEIIKDaANNAIGIRSKATITKNK 270
Cdd:PRK09354 173 SQALRKLTGNISKSNTTVIFINQIREKIGVMFGNPETTTGGNALKFYASVRLDIRRIGTIKD-GDEVIGNRTKVKVVKNK 251
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 499426257 271 LSTPMTTTYIDFYFKSGISEVNEIIDLAIDYQIIEQSGSWFSYQKEKIAQGKANLITKLGESEELYKLIKTEVLNKLK 348
Cdd:PRK09354 252 VAPPFKQAEFDIMYGEGISREGELIDLGVELGIIEKSGAWYSYNGEKIGQGRENAKQYLKENPELADEIEKKIREKLG 329
|
|
| RecA |
COG0468 |
RecA/RadA recombinase [Replication, recombination and repair]; |
32-347 |
1.33e-141 |
|
RecA/RadA recombinase [Replication, recombination and repair];
Pssm-ID: 440236 [Multi-domain] Cd Length: 351 Bit Score: 404.94 E-value: 1.33e-141
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 32 VLKLLQQKFGKTNIYLNEKDELKDLEAISTGSIKLDHALGTDGFIKGRIVEIYGNESCGKTTLALSTIKQAIDRNMRVAF 111
Cdd:COG0468 17 ALSQIEKQFGKGSIMRLGDKARQDVEVISTGSLALDIALGVGGLPRGRIVEIYGPESSGKTTLALHAIAEAQKAGGIAAF 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 112 IDAEHALDLRYVKRLGIDLTKLIIARPDYGEQGFEIIKSLIKTELIDLIVVDSVAALVPKVEIEGKMEDQTMGTHARMMS 191
Cdd:COG0468 97 IDAEHALDPEYAKKLGVDIDNLLVSQPDTGEQALEIAETLVRSGAVDLIVVDSVAALVPKAEIEGEMGDSHVGLQARLMS 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 192 RGLSRIQPLLAKHNVSVIFINQLREKVGIMFGNPEVTTGGKALKFYSSTRLELRRAEIIKDaANNAIGIRSKATITKNKL 271
Cdd:COG0468 177 QALRKLTGAISKSNTTVIFINQLREKIGVMFGNPETTTGGNALKFYASVRLDIRRIGTIKD-GDEVIGNRTRVKVVKNKV 255
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 499426257 272 STPMTTTYIDFYFKSGISEVNEIIDLAIDYQIIEQSGSWFSYQKEKIAQGKANLITKLGESEELYKLIKTEVLNKL 347
Cdd:COG0468 256 APPFKEAEFDIMYGEGISKEGELLDLAVELGIIEKSGAWYSYGGERLGQGRENAKQFLKENPELAEEIEAKIREKL 331
|
|
| tigrfam_recA |
TIGR02012 |
protein RecA; This model describes orthologs of the recA protein. RecA promotes hybridization ... |
33-343 |
2.42e-125 |
|
protein RecA; This model describes orthologs of the recA protein. RecA promotes hybridization of homolgous regions of DNA. A segment of ssDNA can be hybridized to another ssDNA region, or to a dsDNA region. ATP is hydrolyzed in the process. Part of the SOS respones, it is regulated by LexA via autocatalytic cleavage. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 162659 [Multi-domain] Cd Length: 321 Bit Score: 362.46 E-value: 2.42e-125
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 33 LKLLQQKFGKTNIYLNEKDELKDLEAISTGSIKLDHALGTDGFIKGRIVEIYGNESCGKTTLALSTIKQAIDRNMRVAFI 112
Cdd:TIGR02012 10 LAQIEKQFGKGSIMRLGEKTVMDVETISTGSLALDLALGVGGLPKGRIIEIYGPESSGKTTLALHAIAEAQKAGGTAAFI 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 113 DAEHALDLRYVKRLGIDLTKLIIARPDYGEQGFEIIKSLIKTELIDLIVVDSVAALVPKVEIEGKMEDQTMGTHARMMSR 192
Cdd:TIGR02012 90 DAEHALDPVYARKLGVDIDNLLVSQPDTGEQALEIAETLVRSGAVDIIVVDSVAALVPKAEIEGEMGDSHVGLQARLMSQ 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 193 GLSRIQPLLAKHNVSVIFINQLREKVGIMFGNPEVTTGGKALKFYSSTRLELRRAEIIKDaANNAIGIRSKATITKNKLS 272
Cdd:TIGR02012 170 ALRKLTGALSKSNTTAIFINQIREKIGVMFGNPETTTGGNALKFYASVRLDIRRIGTVKQ-GEEVVGNRTKVKVVKNKVA 248
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 499426257 273 TPMTTTYIDFYFKSGISEVNEIIDLAIDYQIIEQSGSWFSYQKEKIAQGKANLITKLGESEELYKLIKTEV 343
Cdd:TIGR02012 249 PPFREAEFDILYGEGISKLGEIIDLAVELDIIKKSGSWYSYGDEKLGQGRENAKAFLKENPELAQEIEKKV 319
|
|
| RecA |
cd00983 |
recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ... |
55-290 |
7.31e-120 |
|
recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange.
Pssm-ID: 410863 [Multi-domain] Cd Length: 235 Bit Score: 345.31 E-value: 7.31e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 55 DLEAISTGSIKLDHALGTDGFIKGRIVEIYGNESCGKTTLALSTIKQAIDRNMRVAFIDAEHALDLRYVKRLGIDLTKLI 134
Cdd:cd00983 1 DVEVIPTGSLSLDIALGIGGLPRGRIIEIYGPESSGKTTLALHAIAEAQKLGGTAAFIDAEHALDPEYAKKLGVDIDNLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 135 IARPDYGEQGFEIIKSLIKTELIDLIVVDSVAALVPKVEIEGKMEDQTMGTHARMMSRGLSRIQPLLAKHNVSVIFINQL 214
Cdd:cd00983 81 VSQPDTGEQALEIADTLIRSGAVDLIVVDSVAALVPKAEIEGEMGDSHVGLQARLMSQALRKLTGSLSKSKTTVIFINQL 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 499426257 215 REKVGIMFGNPEVTTGGKALKFYSSTRLELRRAEIIKDaANNAIGIRSKATITKNKLSTPMTTTYIDFYFKSGISE 290
Cdd:cd00983 161 REKIGVMFGNPETTTGGNALKFYASVRLDIRRIELIKE-GEDVIGNRTKVKVVKNKVAPPFKQAEFDILYGEGISR 235
|
|
| RecA |
pfam00154 |
recA bacterial DNA recombination protein; RecA is a DNA-dependent ATPase and functions in DNA ... |
33-289 |
1.07e-111 |
|
recA bacterial DNA recombination protein; RecA is a DNA-dependent ATPase and functions in DNA repair systems. RecA protein catalyzes an ATP-dependent DNA strand-exchange reaction that is the central step in the repair of dsDNA breaks by homologous recombination.
Pssm-ID: 425488 [Multi-domain] Cd Length: 262 Bit Score: 325.89 E-value: 1.07e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 33 LKLLQQKFGKTNIYLNEKDELKDLEAISTGSIKLDHALGTDGFIKGRIVEIYGNESCGKTTLALSTIKQAIDRNMRVAFI 112
Cdd:pfam00154 7 LKQIEKQFGKGSIMKLGDEKKLDVETISTGSLALDIALGIGGYPKGRIIEIYGPESSGKTTLALHAIAEAQKAGGTAAFI 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 113 DAEHALDLRYVKRLGIDLTKLIIARPDYGEQGFEIIKSLIKTELIDLIVVDSVAALVPKVEIEGKMEDQTMGTHARMMSR 192
Cdd:pfam00154 87 DAEHALDPVYAKKLGVDIDNLLVSQPDTGEQALEIADMLVRSGAIDLIVVDSVAALVPKAEIEGEMGDSHVGLQARLMSQ 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 193 GLSRIQPLLAKHNVSVIFINQLREKVGIMFGNPEVTTGGKALKFYSSTRLELRRAEIIKDaANNAIGIRSKATITKNKLS 272
Cdd:pfam00154 167 ALRKLTGSISKSNTTVIFINQIREKIGVMFGNPETTTGGRALKFYASVRLDIRRIGQIKQ-GEEVIGNKTKVKVVKNKVA 245
|
250
....*....|....*..
gi 499426257 273 TPMTTTYIDFYFKSGIS 289
Cdd:pfam00154 246 PPFKEAEFDIMYGEGIS 262
|
|
| recA |
PRK09519 |
intein-containing recombinase RecA; |
36-270 |
2.97e-71 |
|
intein-containing recombinase RecA;
Pssm-ID: 77219 [Multi-domain] Cd Length: 790 Bit Score: 236.53 E-value: 2.97e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 36 LQQKFGKTNIYLNEKDELKDLEAISTGSIKLDHALGTDGFIKGRIVEIYGNESCGKTTLALSTIKQAIDRNMRVAFIDAE 115
Cdd:PRK09519 18 IEKSYGKGSVMRLGDEARQPISVIPTGSIALDVALGIGGLPRGRVIEIYGPESSGKTTVALHAVANAQAAGGVAAFIDAE 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 116 HALDLRYVKRLGIDLTKLIIARPDYGEQGFEIIKSLIKTELIDLIVVDSVAALVPKVEIEGKMEDQTMGTHARMMSRGLS 195
Cdd:PRK09519 98 HALDPDYAKKLGVDTDSLLVSQPDTGEQALEIADMLIRSGALDIVVIDSVAALVPRAELEGEMGDSHVGLQARLMSQALR 177
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 499426257 196 RIQPLLAKHNVSVIFINQLREKVGIMFGNPEVTTGGKALKFYSSTRLELRRAEIIKDaANNAIGIRSKATITKNK 270
Cdd:PRK09519 178 KMTGALNNSGTTAIFINQLRDKIGVMFGSPETTTGGKALKFYASVRMDVRRVETLKD-GTNAVGNRTRVKVVKNK 251
|
|
| RecA-like |
cd01393 |
RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ... |
78-246 |
7.31e-38 |
|
RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange. While prokaryotes have a single RecA protein, eukaryotes have multiple RecA homologs such as Rad51, DMC1 and Rad55/57. Archaea have the RecA-like homologs RadA and RadB.
Pssm-ID: 410881 [Multi-domain] Cd Length: 185 Bit Score: 134.02 E-value: 7.31e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 78 GRIVEIYGNESCGKTTLALSTIKQAIDRNMRVAFIDAEHALDLRYVKRL-----------GIDLTKLIIARPDYGEQGFE 146
Cdd:cd01393 1 GKITEIYGPPGSGKTQLALQLAANALLLGGGVVWIDTEGAFPPSRLVQIleaspsselelAEALSRLLYFRPPDTLAHLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 147 IIKSLIKT----ELIDLIVVDSVAALVPKVEIEGKMEDQTMGTHARMMSRGLSRIQPLLAKHNVSVIFINQLREKVGIMF 222
Cdd:cd01393 81 ALDSLPESlfppPNTSLVVVDSVSALFRKAFPRGGDGDSSSSLRARLLSQLARALQKLAAQFNLAVVVTNQVTTKIRGGS 160
|
170 180
....*....|....*....|....*
gi 499426257 223 G-NPEVTTGGKALKFYSSTRLELRR 246
Cdd:cd01393 161 GaSLVPPALGNTWEHSVSTRLLLYR 185
|
|
| archRadB |
cd01394 |
archaeal RadB; The archaeal protein RadB shares similarity RadA, the archaeal functional ... |
59-251 |
2.94e-17 |
|
archaeal RadB; The archaeal protein RadB shares similarity RadA, the archaeal functional homologue to the bacterial RecA. The precise function of RadB is unclear.
Pssm-ID: 410882 [Multi-domain] Cd Length: 216 Bit Score: 79.28 E-value: 2.94e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 59 ISTGSIKLDHALGtDGFIKGRIVEIYGNESCGKTTLALSTIKQAIDRNMRVAFIDAEhALDLRYVK-----RLGIDLTKL 133
Cdd:cd01394 1 LSTGSKSLDSLLG-GGVERGTITQIYGPPGSGKTNICLQLAVEAAKQGKKVVYIDTE-GLSPERFQqiageRFESIASNI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 134 IIARP-DYGEQGFEI--IKSLIKTELIDLIVVDSVAALVpkveiegKMEDQTMGTHARMMSRGLSRIQPLLAKHNVSVIF 210
Cdd:cd01394 79 IVFEPySFDEQGVAIqeAEKLLKSDKVDLVVVDSATALY-------RLELGDDSEANRELSRQMSKLLSIARKYDIPVVI 151
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 499426257 211 INQlrekVGIMFGNPEVT-TGGKALKFYSST--RLE-----LRRAEIIK 251
Cdd:cd01394 152 TNQ----VYSDIDDDRLKpVGGTLLEHWSKAiiRLEksppgLRRATLEK 196
|
|
| radB |
PRK09361 |
DNA repair and recombination protein RadB; Provisional |
57-251 |
1.37e-16 |
|
DNA repair and recombination protein RadB; Provisional
Pssm-ID: 236482 [Multi-domain] Cd Length: 225 Bit Score: 77.59 E-value: 1.37e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 57 EAISTGSIKLDHALGtDGFIKGRIVEIYGNESCGKTTLALSTIKQAIDRNMRVAFIDAEhALDLRYVKRLGID-----LT 131
Cdd:PRK09361 3 ERLPTGCKMLDELLG-GGFERGTITQIYGPPGSGKTNICLQLAVEAAKNGKKVIYIDTE-GLSPERFKQIAGEdfeelLS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 132 KLIIARP-DYGEQGfEIIKSLIK--TELIDLIVVDSVAALVpKVEIEGKMEDQTMgthARMMSRGLSRIQPLLAKHNVSV 208
Cdd:PRK09361 81 NIIIFEPsSFEEQS-EAIRKAEKlaKENVGLIVLDSATSLY-RLELEDEEDNSKL---NRELGRQLTHLLKLARKHDLAV 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 499426257 209 IFINQLREKVgimfGNPEVT-TGGKALKFYSST--RLE-----LRRAEIIK 251
Cdd:PRK09361 156 VITNQVYSDI----DSDGLRpLGGHTLEHWSKTilRLEkfrngKRRATLEK 202
|
|
| Rad51 |
pfam08423 |
Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ... |
59-246 |
1.11e-15 |
|
Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ATPase RecA protein.
Pssm-ID: 462471 [Multi-domain] Cd Length: 255 Bit Score: 75.80 E-value: 1.11e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 59 ISTGSIKLDHALGtDGFIKGRIVEIYGNESCGKT----TLALsTIKQAIDR---NMRVAFIDAEHALD----LRYVKRLG 127
Cdd:pfam08423 19 ITTGSKELDKLLG-GGIETGSITEIFGEFRTGKTqlchTLCV-TCQLPLEMgggEGKALYIDTEGTFRperlVAIAERYG 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 128 ID----LTKLIIARP---DYGEQGFEIIKSLIKTELIDLIVVDSVAALVpKVEIEGKMEDQTMGTHarmMSRGLSRIQPL 200
Cdd:pfam08423 97 LDpedvLDNVAYARAynsEHQMQLLQQAAAMMSESRFALLIVDSATALY-RTDFSGRGELAERQQH---LAKFLRTLQRL 172
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 499426257 201 LAKHNVSVIFINQLREKVG---IMF-GNPEVTTGGKALKFYSSTRLELRR 246
Cdd:pfam08423 173 ADEFGVAVVITNQVVAQVDgaaGMFsGDPKKPIGGHIMAHASTTRLSLRK 222
|
|
| recomb_radB |
TIGR02237 |
DNA repair and recombination protein RadB; This family consists exclusively of archaeal RadB ... |
66-251 |
2.05e-15 |
|
DNA repair and recombination protein RadB; This family consists exclusively of archaeal RadB protein, a homolog of bacterial RecA (TIGR02012), eukaryotic RAD51 (TIGR02239) and DMC1 (TIGR02238), and archaeal RadA (TIGR02236).
Pssm-ID: 274047 [Multi-domain] Cd Length: 209 Bit Score: 73.99 E-value: 2.05e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 66 LDHALGtDGFIKGRIVEIYGNESCGKTTLALSTIKQAIDRNMRVAFIDAEhALDLRYVK-----RLGIDLTKLIIARP-D 139
Cdd:TIGR02237 1 IDELLG-GGVERGTITQIYGPPGSGKTNICMILAVNAARQGKKVVYIDTE-GLSPERFKqiaedRPERALSNFIVFEVfD 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 140 YGEQGFEIIK--SLIKTELIDLIVVDSVAALvpkVEIEGKMEDQTMgthARMMSRGLSRIQPLLAKHNVSVIFINQLREK 217
Cdd:TIGR02237 79 FDEQGVAIQKtsKFIDRDSASLVVVDSFTAL---YRLELSDDRISR---NRELARQLTLLLSLARKKNLAVVITNQVYTD 152
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 499426257 218 VGIMFGNPevtTGGKALKFYSST--RLE----LRRAEIIK 251
Cdd:TIGR02237 153 VNNGTLRP---LGGHLLEHWSKVilRLEkfrgRRLATLEK 189
|
|
| DMC1 |
cd19514 |
homologous-pairing protein DMC1; DMC1 has a central role in homologous recombination in ... |
59-246 |
3.09e-15 |
|
homologous-pairing protein DMC1; DMC1 has a central role in homologous recombination in meiosis. It assembles at the sites of programmed DNA double-strand breaks and carries out a search for allelic DNA sequences located on homologous chromatids. It forms octameric rings.
Pssm-ID: 410922 [Multi-domain] Cd Length: 236 Bit Score: 73.93 E-value: 3.09e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 59 ISTGSIKLDHALGtDGFIKGRIVEIYGNESCGKTTLA--LSTIKQaIDRNM-----RVAFIDAEHAL---DLRYV-KRLG 127
Cdd:cd19514 1 ISTGSTELDKLLG-GGIESMSITEVFGEFRTGKTQLShtLCVTAQ-LPGSMgggggKVAYIDTEGTFrpdRIRPIaERFG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 128 ID----LTKLIIARPDYGEQGFEII----KSLIKTELIDLIVVDSVAALVpKVEIEGKME----DQTMGTHarmmsrgLS 195
Cdd:cd19514 79 VDhdavLDNILYARAYTSEHQMELLdyvaAKFHEEAVFRLLIIDSIMALF-RVDFSGRGElaerQQKLAQM-------LS 150
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 499426257 196 RIQPLLAKHNVSVIFINQLREKVG--IMF-GNPEVTTGGKALKFYSSTRLELRR 246
Cdd:cd19514 151 RLQKISEEYNVAVFITNQVTADPGaaMTFqADPKKPIGGHILAHASTTRISLRK 204
|
|
| Rad51_DMC1_archRadA |
cd01123 |
recombinase Rad51, DMC1, and archaeal RadA; This group of recombinases includes the eukaryotic ... |
59-246 |
2.15e-13 |
|
recombinase Rad51, DMC1, and archaeal RadA; This group of recombinases includes the eukaryotic proteins RAD51, RAD55/57 and the meiosis-specific protein DMC1, and the archaeal protein RadA. They are closely related to the bacterial RecA group. Rad51 proteins catalyze a similar recombination reaction as RecA, using ATP-dependent DNA binding activity and a DNA-dependent ATPase. However, this reaction is less efficient and requires accessory proteins such as RAD55/57 .
Pssm-ID: 410868 [Multi-domain] Cd Length: 234 Bit Score: 68.71 E-value: 2.15e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 59 ISTGSIKLDHALGtDGFIKGRIVEIYGNESCGKT----TLALsTIKQAIDR---NMRVAFIDAEHALD---LRYV-KRLG 127
Cdd:cd01123 1 ITTGSKELDKLLG-GGIETGSITEMFGEFRTGKTqlchTLAV-TCQLPIDRgggEGKAIYIDTEGTFRperLRAIaQRFG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 128 ID----LTKLIIARP---DYGEQGFEIIKSLIKTELIDLIVVDSVAALVpKVEIEGKMEdqtMGTHARMMSRGLSRIQPL 200
Cdd:cd01123 79 LDpddvLDNVAYARAfnsDHQTQLLDQAAAMMVESRFKLLIVDSATALY-RTDYSGRGE---LSARQMHLAKFLRMLQRL 154
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 499426257 201 LAKHNVSVIFINQLREKVG---IMFGNPEVTTGGKALKFYSSTRLELRR 246
Cdd:cd01123 155 ADEFGVAVVVTNQVVAQVDgamMFAADPKKPIGGNILAHASTTRLYLRK 203
|
|
| PLN03187 |
PLN03187 |
meiotic recombination protein DMC1 homolog; Provisional |
54-255 |
5.01e-13 |
|
meiotic recombination protein DMC1 homolog; Provisional
Pssm-ID: 215620 [Multi-domain] Cd Length: 344 Bit Score: 69.04 E-value: 5.01e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 54 KDLEAISTGSIKLDHALGtDGFIKGRIVEIYGNESCGKT----TLALSTikqAIDRNMR-----VAFIDAEHALDLRYVK 124
Cdd:PLN03187 103 KSVVRITTGSQALDELLG-GGIETRCITEAFGEFRSGKTqlahTLCVTT---QLPTEMGggngkVAYIDTEGTFRPDRIV 178
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 125 ----RLGID----LTKLIIARPDYGEQGFEIIKSL---IKTELIDLIVVDSVAALVpKVEIEGKMEdqtMGTHARMMSRG 193
Cdd:PLN03187 179 piaeRFGMDadavLDNIIYARAYTYEHQYNLLLGLaakMAEEPFRLLIVDSVIALF-RVDFTGRGE---LAERQQKLAQM 254
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 194 LSRIQPLLAKHNVSVIFINQLREKVG--IMFGNPEVTTGGKALKFYSSTRLELRR----AEIIK--DAAN 255
Cdd:PLN03187 255 LSRLTKIAEEFNVAVYMTNQVIADPGggMFISDPKKPAGGHVLAHAATIRLMLRKgkgeQRVCKvfDAPN 324
|
|
| recomb_DMC1 |
TIGR02238 |
meiotic recombinase Dmc1; This model describes DMC1, a subfamily of a larger family of DNA ... |
59-246 |
1.10e-12 |
|
meiotic recombinase Dmc1; This model describes DMC1, a subfamily of a larger family of DNA repair and recombination proteins. It is eukaryotic only and most closely related to eukaryotic RAD51. It also resembles archaeal RadA (TIGR02236) and RadB (TIGR02237) and bacterial RecA (TIGR02012). It has been characterized for human as a recombinase active only in meiosis.
Pssm-ID: 131292 [Multi-domain] Cd Length: 313 Bit Score: 67.88 E-value: 1.10e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 59 ISTGSIKLDHALGtDGFIKGRIVEIYGNESCGKTTLA--LSTIKQaIDRNM-----RVAFIDAEHALDLRYVK----RLG 127
Cdd:TIGR02238 78 ITTGSQALDGILG-GGIESMSITEVFGEFRCGKTQLShtLCVTAQ-LPREMgggngKVAYIDTEGTFRPDRIRaiaeRFG 155
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 128 ID----LTKLIIARPDYGEQGFEIIKSL---IKTELIDLIVVDSVAALVpKVEIEGKMEdqtMGTHARMMSRGLSRIQPL 200
Cdd:TIGR02238 156 VDpdavLDNILYARAYTSEHQMELLDYLaakFSEEPFRLLIVDSIMALF-RVDFSGRGE---LSERQQKLAQMLSRLNKI 231
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 499426257 201 LAKHNVSVIFINQLREKVG--IMF-GNPEVTTGGKALKFYSSTRLELRR 246
Cdd:TIGR02238 232 SEEFNVAVFVTNQVQADPGatMTFiADPKKPIGGHVLAHASTTRILLRK 280
|
|
| RAD55 |
COG0467 |
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms]; |
59-216 |
3.52e-12 |
|
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms];
Pssm-ID: 440235 [Multi-domain] Cd Length: 221 Bit Score: 64.94 E-value: 3.52e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 59 ISTGSIKLDHALGtDGFIKGRIVEIYGNESCGKTTLALSTIKQAIDRNMRVAFIDAEHALD--LRYVKRLGIDLTKLII- 135
Cdd:COG0467 2 VPTGIPGLDELLG-GGLPRGSSTLLSGPPGTGKTTLALQFLAEGLRRGEKGLYVSFEESPEqlLRRAESLGLDLEEYIEs 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 136 -------ARPDYGEQGFE----IIKSLIKTELIDLIVVDSVAALvpkveiEGKMEDQTMgthARMMSRGLSRIqplLAKH 204
Cdd:COG0467 81 gllriidLSPEELGLDLEellaRLREAVEEFGAKRVVIDSLSGL------LLALPDPER---LREFLHRLLRY---LKKR 148
|
170
....*....|..
gi 499426257 205 NVSVIFINQLRE 216
Cdd:COG0467 149 GVTTLLTSETGG 160
|
|
| PTZ00035 |
PTZ00035 |
Rad51 protein; Provisional |
59-247 |
8.93e-12 |
|
Rad51 protein; Provisional
Pssm-ID: 185407 [Multi-domain] Cd Length: 337 Bit Score: 65.40 E-value: 8.93e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 59 ISTGSIKLDHALGtDGFIKGRIVEIYGNESCGKTTLA--LSTIKQAIDR----NMRVAFIDAEHALDLRYV----KRLGI 128
Cdd:PTZ00035 100 ITTGSTQLDKLLG-GGIETGSITELFGEFRTGKTQLChtLCVTCQLPIEqgggEGKVLYIDTEGTFRPERIvqiaERFGL 178
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 129 D----LTKLIIARPDYGEQGFEII---KSLIKTELIDLIVVDSVAALVpKVEIEGKMEdqtmgTHARMMSRG--LSRIQP 199
Cdd:PTZ00035 179 DpedvLDNIAYARAYNHEHQMQLLsqaAAKMAEERFALLIVDSATALF-RVDYSGRGE-----LAERQQHLGkfLRALQK 252
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 499426257 200 LLAKHNVSVIFINQLREKVG---IMFGNPEVTTGGKALKFYSSTRLELRRA 247
Cdd:PTZ00035 253 LADEFNVAVVITNQVMADVDgasMFVADPKKPIGGHIIAHASTTRLSLRKG 303
|
|
| PLN03186 |
PLN03186 |
DNA repair protein RAD51 homolog; Provisional |
54-246 |
5.80e-11 |
|
DNA repair protein RAD51 homolog; Provisional
Pssm-ID: 178728 [Multi-domain] Cd Length: 342 Bit Score: 62.83 E-value: 5.80e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 54 KDLEAISTGSIKLDHALGtDGFIKGRIVEIYGNESCGKT----TLALsTIKQAIDRNM---RVAFIDAEHALD----LRY 122
Cdd:PLN03186 100 QEIIQITTGSRELDKILE-GGIETGSITEIYGEFRTGKTqlchTLCV-TCQLPLDQGGgegKAMYIDTEGTFRpqrlIQI 177
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 123 VKRLGID----LTKLIIARPDYGEQGFEIIK---SLIKTELIDLIVVDSVAALVpKVEIEGKMEDQTMGTHarmMSRGLS 195
Cdd:PLN03186 178 AERFGLNgadvLENVAYARAYNTDHQSELLLeaaSMMAETRFALMIVDSATALY-RTEFSGRGELSARQMH---LGKFLR 253
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 499426257 196 RIQPLLAKHNVSVIFINQLREKV--GIMFGNPEVT-TGGKALKFYSSTRLELRR 246
Cdd:PLN03186 254 SLQRLADEFGVAVVITNQVVAQVdgSAFFAGPQLKpIGGNIMAHASTTRLALRK 307
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
77-248 |
1.02e-09 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 56.61 E-value: 1.02e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 77 KGRIVEIYGNESCGKTTLALSTIKQAIDRNMRVAFIDAEHALDLRYVKRLGIDLTklIIARPDYGEQGFEIIKSLIKTEL 156
Cdd:smart00382 1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIYIDGEDILEEVLDQLLLIIVG--GKKASGSGELRLRLALALARKLK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 157 IDLIVVDSVAALVPKVEiegkmedqtmgTHARMMSRGLSRIQPLLAKHNVSVIFINqlrekvgimfgNPEVTTGGKALKF 236
Cdd:smart00382 79 PDVLILDEITSLLDAEQ-----------EALLLLLEELRLLLLLKSEKNLTVILTT-----------NDEKDLGPALLRR 136
|
170
....*....|..
gi 499426257 237 YSSTRLELRRAE 248
Cdd:smart00382 137 RFDRRIVLLLIL 148
|
|
| KaiC_C |
cd19484 |
C-terminal domain of Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most ... |
59-168 |
6.13e-09 |
|
C-terminal domain of Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.
Pssm-ID: 410892 [Multi-domain] Cd Length: 218 Bit Score: 55.41 E-value: 6.13e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 59 ISTGSIKLDHALGTDGFIKGRIVEIYGNESCGKTTLALSTIKQAIDRNMRVAFIDAEHALD--LRYVKRLGIDLT----- 131
Cdd:cd19484 1 ISTGIPRLDAMLGGGGFFRGSSILVSGATGTGKTLLAASFADAACRRGERCLYFAFEESPAqlIRNAKSIGIDLEqmerk 80
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 499426257 132 ---KLIIARPD-YG-EQGFEIIKSLIKTELIDLIVVDSVAAL 168
Cdd:cd19484 81 gllKIICARPElYGlEDHLIIIKSEINEFKPSRVIVDPLSAL 122
|
|
| recomb_RAD51 |
TIGR02239 |
DNA repair protein RAD51; This eukaryotic sequence family consists of RAD51, a protein ... |
54-246 |
9.65e-09 |
|
DNA repair protein RAD51; This eukaryotic sequence family consists of RAD51, a protein involved in DNA homologous recombination and repair. It is similar in sequence the exclusively meiotic recombinase DMC1 (TIGR02238), to archaeal families RadA (TIGR02236) and RadB (TIGR02237), and to bacterial RecA (TIGR02012).
Pssm-ID: 274048 [Multi-domain] Cd Length: 316 Bit Score: 55.89 E-value: 9.65e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 54 KDLEAISTGSIKLDHALGtDGFIKGRIVEIYGNESCGKT----TLALsTIKQAIDR---NMRVAFIDAEHALD----LRY 122
Cdd:TIGR02239 73 QEVIQLTTGSKELDKLLG-GGIETGSITEIFGEFRTGKTqlchTLAV-TCQLPIDQgggEGKALYIDTEGTFRperlLAI 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 123 VKRLGID----LTKLIIARPDYGEQGFEII---KSLIKTELIDLIVVDSVAALVpKVEIEGKMEDQTMGTHarmMSRGLS 195
Cdd:TIGR02239 151 AERYGLNpedvLDNVAYARAYNTDHQLQLLqqaAAMMSESRFALLIVDSATALY-RTDFSGRGELSARQMH---LARFLR 226
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 499426257 196 RIQPLLAKHNVSVIFINQLREKV---GIMF-GNPEVTTGGKALKFYSSTRLELRR 246
Cdd:TIGR02239 227 SLQRLADEFGVAVVITNQVVAQVdgaGSMFaGDPKKPIGGNIMAHASTTRLSLRK 281
|
|
| Rad51B |
cd19493 |
RAD51B recombinase; RAD51B recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
67-246 |
1.09e-08 |
|
RAD51B recombinase; RAD51B recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51B, together with the other RAD51 paralogs, RAD51C, RAD51D, XRCC3, and XRCC2, helps recruit RAD51 to the break site.
Pssm-ID: 410901 [Multi-domain] Cd Length: 222 Bit Score: 55.02 E-value: 1.09e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 67 DHALGtDGFIKGRIVEIYGNESCGKTTLALSTIKQAI------DRNMRVAFIDAEHALdlrYVKRLGIDLTKLiIARPDY 140
Cdd:cd19493 1 DTALA-GGLPLGAITEITGASGSGKTQFALTLASSAAmparkgGLDGGVLYIDTESKF---SAERLAEIAEAR-FPEAFS 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 141 GEQGFE-----------IIKSLIKTELID---------------LIVVDSVAALVPKvEIEGKMEDQT-----MGTHARM 189
Cdd:cd19493 76 GFMEENeraeemlkrvaVVRVTTLAQLLErlpnleehilssgvrLVVIDSIAALVRR-EFGGSDGEVTerhnaLAREASS 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 190 MSRglsriqplLA-KHNVSVIFINQLREKVGIMFGNPEVTTG--GKALKFYSSTRLELRR 246
Cdd:cd19493 155 LKR--------LAeEFRIAVLVTNQATTHFGDAGDGSSGVTAalGDAWAHAVNTRLRLER 206
|
|
| RadA_SMS_N |
cd01121 |
bacterial RadA DNA repair protein; Sms or bacterial RadA is a DNA repair protein that plays a ... |
52-165 |
1.89e-08 |
|
bacterial RadA DNA repair protein; Sms or bacterial RadA is a DNA repair protein that plays a role in recombination and recombinational repair of DNA damaged by UV radiation, X-rays, and chemical agent and is responsible for the stabilization or processing of branched DNA molecules.
Pssm-ID: 410866 [Multi-domain] Cd Length: 268 Bit Score: 54.84 E-value: 1.89e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 52 ELKDLEAISTGSIKLDHALGtDGFIKGRIVEIYGNESCGKTTLALSTIKQAIDRNMRVAFIDAEHALD---LRyVKRLGI 128
Cdd:cd01121 57 EAEEEERISTGIGELDRVLG-GGLVPGSVVLIGGDPGIGKSTLLLQVAARLAQRGGKVLYVSGEESLSqikLR-AERLGL 134
|
90 100 110
....*....|....*....|....*....|....*..
gi 499426257 129 DLTKLIIARpdygEQGFEIIKSLIKTELIDLIVVDSV 165
Cdd:cd01121 135 GSDNLYLLA----ETNLEAILAEIEELKPSLVVIDSI 167
|
|
| recA |
PRK09519 |
intein-containing recombinase RecA; |
237-347 |
4.81e-08 |
|
intein-containing recombinase RecA;
Pssm-ID: 77219 [Multi-domain] Cd Length: 790 Bit Score: 54.71 E-value: 4.81e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 237 YSSTR--LELRRAEIIKDAANNAIGIRSKATITKNkLSTPMTTTYIDFYFKSGISEVNEIIDLAIDYQIIEQSGSWFSYQ 314
Cdd:PRK09519 657 YSVIRevLPTRRARTFDLEVEELHTLVAEGVVVHN-CSPPFKQAEFDILYGKGISREGSLIDMGVDQGLIRKSGAWFTYE 735
|
90 100 110
....*....|....*....|....*....|...
gi 499426257 315 KEKIAQGKANLITKLGESEELYKLIKTEVLNKL 347
Cdd:PRK09519 736 GEQLGQGKENARNFLVENADVADEIEKKIKEKL 768
|
|
| PRK09302 |
PRK09302 |
circadian clock protein KaiC; Reviewed |
57-176 |
1.45e-07 |
|
circadian clock protein KaiC; Reviewed
Pssm-ID: 236461 [Multi-domain] Cd Length: 509 Bit Score: 52.96 E-value: 1.45e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 57 EAISTGSIKLDHALGtDGFIKGRIVEIYGNESCGKTTLALSTIKQAIDRNMRVAFIDAEHALD--LRYVKRLGIDLT--- 131
Cdd:PRK09302 253 ERISSGVPDLDEMLG-GGFFRGSIILVSGATGTGKTLLASKFAEAACRRGERCLLFAFEESRAqlIRNARSWGIDLEkme 331
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 499426257 132 -----KLIIARPD-YG-EQGFEIIKSLIKTELIDLIVVDSVAALVPKVEIEG 176
Cdd:PRK09302 332 ekgllKIICARPEsYGlEDHLIIIKREIEEFKPSRVAIDPLSALARGGSLNE 383
|
|
| archRadA |
cd19515 |
archaeal recombinase Rad51/RadA; This group includes the archaeal protein RadA which is a ... |
59-246 |
3.64e-07 |
|
archaeal recombinase Rad51/RadA; This group includes the archaeal protein RadA which is a homolog of Rad51. RAD51 recombinase plays an essential role in DNA repair by homologous recombination (HR)
Pssm-ID: 410923 [Multi-domain] Cd Length: 233 Bit Score: 50.44 E-value: 3.64e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 59 ISTGSIKLDHALGtdGFIKGR-IVEIYGNESCGKTTLA--LSTIKQAIDR----NMRVAFIDAEHALD----LRYVKRLG 127
Cdd:cd19515 1 ISTGSKELDKLLG--GGIETQaITEVFGEFGSGKTQLChqLAVNVQLPPEegglNGKAVYIDTENTFRperiMQMAKALG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 128 ID----LTKLIIARPdYG--------EQGFEIIKsliKTELIDLIVVDSVAALVpKVEIEGK----MEDQTMGTHARMms 191
Cdd:cd19515 79 LDpdevLDNIYVARA-YNsnhqmllvEKAEDLIK---EGNNIKLLIVDSLTSHF-RAEYVGRgtlaERQQKLNKHLHD-- 151
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 499426257 192 rgLSRIQPLlakHNVSVIFINQLREKVGIMFGNPEVTTGGKALKFYSSTRLELRR 246
Cdd:cd19515 152 --LHRLADL---YNIAVLVTNQVMAKPDAFFGDPTQAIGGHILGHAATFRVYLRK 201
|
|
| radA |
PRK04301 |
DNA repair and recombination protein RadA; Validated |
50-247 |
4.76e-07 |
|
DNA repair and recombination protein RadA; Validated
Pssm-ID: 235273 [Multi-domain] Cd Length: 317 Bit Score: 50.65 E-value: 4.76e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 50 KDELKDLEAISTGSIKLDHALGtdGFIKGR-IVEIYGNESCGKTTLA--LSTIKQAIDR----NMRVAFIDAEHALD--- 119
Cdd:PRK04301 75 LERRKNVGKITTGSKELDELLG--GGIETQsITEFYGEFGSGKTQIChqLAVNVQLPEEkgglEGKAVYIDTEGTFRper 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 120 -LRYVKRLGID----LTKLIIARPD-------YGEQGFEIIKsliKTELIDLIVVDSVAAlvpkveiegkmedqtmgtHA 187
Cdd:PRK04301 153 iEQMAEALGLDpdevLDNIHVARAYnsdhqmlLAEKAEELIK---EGENIKLVIVDSLTA------------------HF 211
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 499426257 188 R--MMSRG-LSRIQPLLAKH-----------NVSVIFINQLREKVGIMFGNPEVTTGGKALKFYSSTRLELRRA 247
Cdd:PRK04301 212 RaeYVGRGnLAERQQKLNKHlhdllrladlyNAAVVVTNQVMARPDAFFGDPTQPIGGHILGHTATFRIYLRKS 285
|
|
| KaiC-like |
cd01124 |
Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. ... |
59-249 |
5.64e-07 |
|
Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.
Pssm-ID: 410869 [Multi-domain] Cd Length: 222 Bit Score: 49.57 E-value: 5.64e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 59 ISTGSIKLDHALGtDGFIKGRIVEIYGNESCGKTTLALSTIKQAIDRNMRVAFIDAEHALD--LRYVKRLGIDLTKLIIA 136
Cdd:cd01124 1 VKTGIPGLDELLG-GGIPKGSVTLLTGGPGTGKTLFGLQFLYAGAKNGEPGLFFTFEESPErlLRNAKSFGWDFDEMEDE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 137 --------------RPDYGEQGfEIIKSLIKTELIDLIVVDSVAALvpkveiEGKMEDQTMgthARMMSRGLSRIqplLA 202
Cdd:cd01124 80 gkliivdappteagRFSLDELL-SRILSIIKSFKAKRVVIDSLSGL------RRAKEDQMR---ARRIVIALLNE---LR 146
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 499426257 203 KHNVSVIFINQLREkvgimfGNPEVTTGGKALKFYSSTRLELRRAEI 249
Cdd:cd01124 147 AAGVTTIFTSEMRS------FLSSESAGGGDVSFIVDGVILLRYVEI 187
|
|
| Rad51D |
cd19489 |
RAD51D recombinase; RAD51D recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
74-248 |
5.95e-07 |
|
RAD51D recombinase; RAD51D recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51D, together with the other RAD51 paralogs, RAD51B, RAD51C, XRCC3, and XRCC2, helps recruit RAD51 to the break site.
Pssm-ID: 410897 [Multi-domain] Cd Length: 209 Bit Score: 49.56 E-value: 5.95e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 74 GFIKGRIVEIYGNESCGKTTLALSTIKQAIDR-NMRVAFID-------------------AEHALD--LRYVKRLGI-DL 130
Cdd:cd19489 3 GLRTGEITELVGESSSGKTQLCLTAAANVASRsGQNVLYIDtkssfsarrlaqilksraqDAEEIDkaLQRIRVVRVfDP 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 131 TKLIiarpdygeQGFEIIKSLIKTEL------IDLIVVDSVAALVPKVeIEGKmedQTMGTHARMMSrgLSRI-QPLLAK 203
Cdd:cd19489 83 YELL--------DLLEELRNTLSQQQenlysrLKLVIIDSLSALISPL-LGGS---KHSEGHALLAS--LARLlKKLAAE 148
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 499426257 204 HNVSVIFINQLREKVGIMFGNPEVTTGGKALKFYSSTRLELRRAE 248
Cdd:cd19489 149 YQIAVLVTNLTVRGGDGGQQGSTKPALGEYWESVPSTRLLLSRDE 193
|
|
| ATPase |
pfam06745 |
KaiC; This family is in the P-loop NTPase superfamily and is found in archaea, bacteria and ... |
59-216 |
8.92e-07 |
|
KaiC; This family is in the P-loop NTPase superfamily and is found in archaea, bacteria and eukaryotes. More than one copy is sometimes found in each protein. This family includes KaiC, which is one of the Kai proteins among which direct protein-protein association may be a critical process in the generation of circadian rhythms in cyanobacteria.
Pssm-ID: 429095 [Multi-domain] Cd Length: 231 Bit Score: 49.17 E-value: 8.92e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 59 ISTGSIKLDhALGTDGFIKGRIVEIYGNESCGKTTLALS-TIKQAIDRNMRVAFIDA-EHALDLRY-VKRLGIDLTKLI- 134
Cdd:pfam06745 1 VKTGIPGLD-EILKGGFPEGRVVLITGGPGTGKTIFGLQfLYNGALKYGEPGVFVTLeEPPEDLREnARSFGWDLEKLEe 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 135 -----------IARPDYGEQGFEIIKSLIKtELIDLI--------VVDSVAALvpkVEIEGKMEdqtmgthARMMSRGLS 195
Cdd:pfam06745 80 egklaiidastSGIGIAEVEDRFDLEELIE-RLREAIreigakrvVIDSITTL---FYLLKPAV-------AREILRRLK 148
|
170 180
....*....|....*....|.
gi 499426257 196 RIqplLAKHNVSVIFINQLRE 216
Cdd:pfam06745 149 RV---LKGLGVTAIFTSEKPS 166
|
|
| XRCC3 |
cd19491 |
XRCC3 recombinase; XRCC3 (X-ray repair complementing defective repair in Chinese hamster cells ... |
66-219 |
1.36e-05 |
|
XRCC3 recombinase; XRCC3 (X-ray repair complementing defective repair in Chinese hamster cells 3) recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. XRCC3, together with the other RAD51 paralogs, RAD51B, RAD51C, RAD51D, and XRCC2, helps recruit RAD51 to the break site.
Pssm-ID: 410899 [Multi-domain] Cd Length: 250 Bit Score: 45.75 E-value: 1.36e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 66 LDHALGtDGFIKGRIVEIYGNESCGKTTLALS---TIKQAIDR---NMRVAFIDAEHAL----------------DLRYV 123
Cdd:cd19491 1 LDELLG-GGIPVGGITEIAGESGAGKTQLCLQlalTVQLPRELgglGGGAVYICTESSFpskrlqqlasslpkryHLEKA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 124 KRLGiDLTkLIIARPDYGEQgFEIIK----SLIKTELIDLIVVDSVAALvpkVEIEGKMEDQTMGTHARMMSRGLSRIQP 199
Cdd:cd19491 80 KNFL-DNI-FVEHVADLETL-EHCLNyqlpALLERGPIRLVVIDSIAAL---FRSEFDTSRSDLVERAKYLRRLADHLKR 153
|
170 180
....*....|....*....|
gi 499426257 200 LLAKHNVSVIFINQLREKVG 219
Cdd:cd19491 154 LADKYNLAVVVVNQVTDRFD 173
|
|
| RepA |
COG3598 |
RecA-family ATPase [Replication, recombination and repair]; |
73-211 |
3.94e-05 |
|
RecA-family ATPase [Replication, recombination and repair];
Pssm-ID: 442817 [Multi-domain] Cd Length: 313 Bit Score: 44.89 E-value: 3.94e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 73 DGFI-KGRIVEIYGNESCGKTTLALS--------------TIKQAidrnmRVAFIDAE-HALDLR-----YVKRLGIDLT 131
Cdd:COG3598 7 PGLLpEGGVTLLAGPPGTGKSFLALQlaaavaaggpwlgrRVPPG-----KVLYLAAEdDRGELRrrlkaLGADLGLPFA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 132 KL-----IIARPDYGE--QGFEIIKSLIKTELIDLIVVDSVAALVPKVEIEgkmedqtmgthARMMSRGLSRIQPLLAKH 204
Cdd:COG3598 82 DLdgrlrLLSLAGDLDdtDDLEALERAIEEEGPDLVVIDPLARVFGGDEND-----------AEEMRAFLNPLDRLAERT 150
|
....*..
gi 499426257 205 NVSVIFI 211
Cdd:COG3598 151 GAAVLLV 157
|
|
| COG4544 |
COG4544 |
Uncharacterized conserved protein [Function unknown]; |
58-139 |
6.25e-05 |
|
Uncharacterized conserved protein [Function unknown];
Pssm-ID: 443609 [Multi-domain] Cd Length: 230 Bit Score: 43.76 E-value: 6.25e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 58 AISTGSIKLDHALGTDGFIKGRIVEIYGNE-SCGKTTLALSTIKQAIDRNMRVAFIDAEHALDLRYVKRLGIDLTKLIIA 136
Cdd:COG4544 28 VLPTGFAALDAALPGGGLPRGALHEILGPApGIGELGLLLPLLARLAQAGGPVLWIAPPYDLYAPGLAAAGLDPERLLLV 107
|
...
gi 499426257 137 RPD 139
Cdd:COG4544 108 RAR 110
|
|
| XRCC2 |
cd19490 |
XRCC2 recombinase; XRCC2 (X-ray repair complementing defective repair in Chinese hamster cells ... |
78-246 |
1.19e-04 |
|
XRCC2 recombinase; XRCC2 (X-ray repair complementing defective repair in Chinese hamster cells 2) recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. XRCC2, together with the other RAD51 paralogs, RAD51B, RAD51C, RAD51D, and XRCC3, helps recruit RAD51 to the break site.
Pssm-ID: 410898 [Multi-domain] Cd Length: 226 Bit Score: 42.72 E-value: 1.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 78 GRIVEIYGNESCGKTTLALSTIKQAI-----------DRNMRVAFIDAEHALD-LRYVKRL------------------G 127
Cdd:cd19490 1 GDVIEITGPSGSGKTELLYHLAARCIlpsswggvplgGLEAAVVFIDTDGRFDiLRLRSILeariraaiqaanssddeeD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 128 ID------LTKLIIARPDYGEQgFEI--------IKSLIKTELIDLIVVDSVAAL-----VPKVEIEGKMEDQTMGTHAr 188
Cdd:cd19490 81 VEeiarecLQRLHIFRCHSSLQ-LLAtllslenyLLSLSANPELGLLLIDSISAFywqdrFSAELARAAPLLQEAALRA- 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 499426257 189 mmsrGLSRIQPLLAKHNVSVIF----INQLREKVGIMFGNPEVTTGGKALKFYSST----------RLELRR 246
Cdd:cd19490 159 ----ILRELRRLRRRFQLVVIAtkqaLFPGKSASTDNPAANNAVSKASAPSHREYLprpwqrlvthRLVLSR 226
|
|
| Rad51C |
cd19492 |
RAD51C recombinase; RAD51C recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
78-248 |
2.46e-04 |
|
RAD51C recombinase; RAD51C recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51C, together with the other RAD51 paralogs, RAD51B, RAD51D, XRCC3, and XRCC2, helps recruit RAD51 to the break site. Additionally, RAD51C acts as a mediator in the early steps of DNA damage signaling.
Pssm-ID: 410900 [Multi-domain] Cd Length: 172 Bit Score: 41.06 E-value: 2.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 78 GRIVEIYGNESCGKTTLAlstIKQAID---------RNMRVAFIDAEHALDLRYVK-RLGIDLTKLIIARPDYgeqgfei 147
Cdd:cd19492 1 GKITEICGVPGVGKTQLC---MQLAVNvqipkcfggLAGEAIYIDTEGSFNIHYFRvHDYVELLALINSLPKF------- 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499426257 148 iksLIKTELIDLIVVDSVAALVpkveiegKMEDQTMGTHARMMSRGLSRIQPLLAKHNVSVIFINQLREKVGIMFGNPEV 227
Cdd:cd19492 71 ---LEDHPKVKLIVVDSIAFPF-------RHDFDDLAQRTRLLNGLAQLLHSLARQHNLAVVLTNQVTTKISEDGQSQLV 140
|
170 180
....*....|....*....|.
gi 499426257 228 TTGGKALKFYSSTRLELRRAE 248
Cdd:cd19492 141 PALGESWSHACTTRLFLTWDE 161
|
|
| PRK08506 |
PRK08506 |
replicative DNA helicase; Provisional |
54-115 |
5.66e-03 |
|
replicative DNA helicase; Provisional
Pssm-ID: 236278 [Multi-domain] Cd Length: 472 Bit Score: 38.45 E-value: 5.66e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 499426257 54 KDLEAISTGSIKLDHAlgTDGFIKGRIVEIYGNESCGKTTLALSTIKQAIDRNMRVAFIDAE 115
Cdd:PRK08506 170 KDIIGLDTGFVELNKM--TKGFNKGDLIIIAARPSMGKTTLCLNMALKALNQDKGVAFFSLE 229
|
|
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