|
Name |
Accession |
Description |
Interval |
E-value |
| rfc |
PRK00440 |
replication factor C small subunit; Reviewed |
1-319 |
0e+00 |
|
replication factor C small subunit; Reviewed
Pssm-ID: 234763 [Multi-domain] Cd Length: 319 Bit Score: 608.41 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 1 MENFEIWVEKYRPRTLDEVVGQDEVIQRLKGYVERKNIPHLLFSGPPGTGKTATAIALARDLFGENWRDNFIEMNASDER 80
Cdd:PRK00440 1 AMMEEIWVEKYRPRTLDEIVGQEEIVERLKSYVKEKNMPHLLFAGPPGTGKTTAALALARELYGEDWRENFLELNASDER 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 81 GIDVVRHKIKEFARTAPIGGAPFKIIFLDEADALTADAQAALRRTMEMYSKSCRFILSCNYVSRIIEPIQSRCAVFRFKP 160
Cdd:PRK00440 81 GIDVIRNKIKEFARTAPVGGAPFKIIFLDEADNLTSDAQQALRRTMEMYSQNTRFILSCNYSSKIIDPIQSRCAVFRFSP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 161 VPKEAMKKRLLEICEKEGVKITEDGLEALIYISGGDFRKAINALQGAAAIGEVVDADTIYQITATARPEEMTELIQTALK 240
Cdd:PRK00440 161 LKKEAVAERLRYIAENEGIEITDDALEAIYYVSEGDMRKAINALQAAAATGKEVTEEAVYKITGTARPEEIREMIELALN 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 499182012 241 GNFMEARELLDRLMVEYGMSGEDIVAQLFREIISMPIKDSLKVQLIDKLGEVDFRLTEGANERIQLDAYLAYLSTLAKK 319
Cdd:PRK00440 241 GDFTEAREKLRDLMIDYGLSGEDIIKQIHREVWSLDIPEELKVELIDAIGEADFRITEGANERIQLEALLAKLALLGKK 319
|
|
| PRK04132 |
PRK04132 |
replication factor C small subunit; Provisional |
52-318 |
9.02e-132 |
|
replication factor C small subunit; Provisional
Pssm-ID: 235223 [Multi-domain] Cd Length: 846 Bit Score: 394.98 E-value: 9.02e-132
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 52 TATAIALARDLFGENWRDNFIEMNASDERGIDVVRHKIKEFARTAPIGGAPFKIIFLDEADALTADAQAALRRTMEMYSK 131
Cdd:PRK04132 580 TTAALALARELFGENWRHNFLELNASDERGINVIREKVKEFARTKPIGGASFKIIFLDEADALTQDAQQALRRTMEMFSS 659
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 132 SCRFILSCNYVSRIIEPIQSRCAVFRFKPVPKEAMKKRLLEICEKEGVKITEDGLEALIYISGGDFRKAINALQGAAAIG 211
Cdd:PRK04132 660 NVRFILSCNYSSKIIEPIQSRCAIFRFRPLRDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMRRAINILQAAAALD 739
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 212 EVVDADTIYQITATARPEEMTELIQTALKGNFMEARELLDRLMVEYGMSGEDIVAQLFREIISMPIKDSLKVQLIDKLGE 291
Cdd:PRK04132 740 DKITDENVFLVASRARPEDIREMMLLALKGNFLKAREKLREILLKQGLSGEDVLVQMHREVFNLPIDEPKKVELADKIGE 819
|
250 260
....*....|....*....|....*..
gi 499182012 292 VDFRLTEGANERIQLDAYLAYLSTLAK 318
Cdd:PRK04132 820 YNFRLVEGANEMIQLEALLAQFTLMGK 846
|
|
| PRK12402 |
PRK12402 |
replication factor C small subunit 2; Reviewed |
6-314 |
3.03e-108 |
|
replication factor C small subunit 2; Reviewed
Pssm-ID: 237090 [Multi-domain] Cd Length: 337 Bit Score: 318.47 E-value: 3.03e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 6 IWVEKYRPRTLDEVVGQDEVIQRLKGYVERKNIPHLLFSGPPGTGKTATAIALARDLFGENWRDNFIEMNASD--ERG-- 81
Cdd:PRK12402 4 LWTEKYRPALLEDILGQDEVVERLSRAVDSPNLPHLLVQGPPGSGKTAAVRALARELYGDPWENNFTEFNVADffDQGkk 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 82 ----------------------IDVVRHKIKEFARTAPIGgAPFKIIFLDEADALTADAQAALRRTMEMYSKSCRFILSC 139
Cdd:PRK12402 84 ylvedprfahflgtdkrirsskIDNFKHVLKEYASYRPLS-ADYKTILLDNAEALREDAQQALRRIMEQYSRTCRFIIAT 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 140 NYVSRIIEPIQSRCAVFRFKPVPKEAMKKRLLEICEKEGVKITEDGLEALIYISGGDFRKAINALQGAAAIGEVVDADTI 219
Cdd:PRK12402 163 RQPSKLIPPIRSRCLPLFFRAPTDDELVDVLESIAEAEGVDYDDDGLELIAYYAGGDLRKAILTLQTAALAAGEITMEAA 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 220 YQ-ITATARPEEMTELIQTALKGNFMEARELLDRLMVEYGMSGEDIVAQLFREIISMPIKDSLkVQLIDKLGEVDFRLTE 298
Cdd:PRK12402 243 YEaLGDVGTDEVIESLLDAAEAGDFTDARKTLDDLLIDEGLSGGEVLEELLRVARSRYRGDNL-ARLHRLAADADARLTD 321
|
330
....*....|....*.
gi 499182012 299 GANERIQLDAYLAYLS 314
Cdd:PRK12402 322 GANDRIQLEALLAELG 337
|
|
| PLN03025 |
PLN03025 |
replication factor C subunit; Provisional |
7-316 |
3.58e-99 |
|
replication factor C subunit; Provisional
Pssm-ID: 178596 [Multi-domain] Cd Length: 319 Bit Score: 294.71 E-value: 3.58e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 7 WVEKYRPRTLDEVVGQDEVIQRLKGYVERKNIPHLLFSGPPGTGKTATAIALARDLFGENWRDNFIEMNASDERGIDVVR 86
Cdd:PLN03025 3 WVEKYRPTKLDDIVGNEDAVSRLQVIARDGNMPNLILSGPPGTGKTTSILALAHELLGPNYKEAVLELNASDDRGIDVVR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 87 HKIKEFAR---TAPIGgaPFKIIFLDEADALTADAQAALRRTMEMYSKSCRFILSCNYVSRIIEPIQSRCAVFRFKPVPK 163
Cdd:PLN03025 83 NKIKMFAQkkvTLPPG--RHKIVILDEADSMTSGAQQALRRTMEIYSNTTRFALACNTSSKIIEPIQSRCAIVRFSRLSD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 164 EAMKKRLLEICEKEGVKITEDGLEALIYISGGDFRKAINALQGAAAIGEVVDADTIYQITATARPEEMTELIQTALKGNF 243
Cdd:PLN03025 161 QEILGRLMKVVEAEKVPYVPEGLEAIIFTADGDMRQALNNLQATHSGFGFVNQENVFKVCDQPHPLHVKNIVRNCLKGKF 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 499182012 244 MEARELLDRLmVEYGMSGEDIVAQLFREIISMPIKDSLKVQLIDKLGEVDFRLTEGANERIQLDAYLAYLSTL 316
Cdd:PLN03025 241 DDACDGLKQL-YDLGYSPTDIITTLFRVVKNYDMPEFLKLEYLREIGFAHMRICDGVGSLLQLSGLLAKLCLV 312
|
|
| HolB |
COG0470 |
DNA polymerase III, delta prime subunit [Replication, recombination and repair]; |
22-316 |
1.23e-82 |
|
DNA polymerase III, delta prime subunit [Replication, recombination and repair];
Pssm-ID: 440238 [Multi-domain] Cd Length: 289 Bit Score: 251.43 E-value: 1.23e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 22 QDEVIQRLKGYVERKNIPH-LLFSGPPGTGKTATAIALARDLFGENWRD------------------NFIEMNA---SDE 79
Cdd:COG0470 1 QEEAWEQLLAAAESGRLPHaLLLHGPPGIGKTTLALALARDLLCENPEGgkacgqchsrlmaagnhpDLLELNPeekSDQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 80 RGIDVVRHkIKEFARTAPIGGaPFKIIFLDEADALTADAQAALRRTMEMYSKSCRFILSCNYVSRIIEPIQSRCAVFRFK 159
Cdd:COG0470 81 IGIDQIRE-LGEFLSLTPLEG-GRKVVIIDEADAMNEAAANALLKTLEEPPKNTPFILIANDPSRLLPTIRSRCQVIRFR 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 160 PVPKEAMKKRLleicEKEGVkiTEDGLEALIYISGGDFRKAINALQGAAAIGEVVDAdtIYQITATARPEEMTELIQTAl 239
Cdd:COG0470 159 PPSEEEALAWL----REEGV--DEDALEAILRLAGGDPRAAINLLQALAGRKELLED--LAALLSRDRALELLDALLKA- 229
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 499182012 240 kgnfmEARELLDRLMveygmsgedivaQLFREIISMPIKDSLKVQLIDKLGEVDFRLTEGANERIQLDAYLAYLSTL 316
Cdd:COG0470 230 -----EALELLDWLL------------KWLLDNLPLEYAGEDLARAYEALSEADRRLGRYANDRLLLEALLAKLGRL 289
|
|
| 44 |
PHA02544 |
clamp loader, small subunit; Provisional |
6-314 |
6.75e-62 |
|
clamp loader, small subunit; Provisional
Pssm-ID: 222866 [Multi-domain] Cd Length: 316 Bit Score: 199.45 E-value: 6.75e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 6 IWVEKYRPRTLDEVVGQDEVIQRLKGYVERKNIPH-LLFSGPPGTGKTATAIALARDLFGEnwrdnFIEMNASDERgIDV 84
Cdd:PHA02544 10 MWEQKYRPSTIDECILPAADKETFKSIVKKGRIPNmLLHSPSPGTGKTTVAKALCNEVGAE-----VLFVNGSDCR-IDF 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 85 VRHKIKEFARTAPIGGaPFKIIFLDEAD-ALTADAQAALRRTMEMYSKSCRFILSCNYVSRIIEPIQSRCAVFRFKpVPK 163
Cdd:PHA02544 84 VRNRLTRFASTVSLTG-GGKVIIIDEFDrLGLADAQRHLRSFMEAYSKNCSFIITANNKNGIIEPLRSRCRVIDFG-VPT 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 164 EA--------MKKRLLEICEKEGVKITEDGLEALIYISGGDFRKAINALQGAAAIGEVvdaDTiyQITATARPEEMTELI 235
Cdd:PHA02544 162 KEeqiemmkqMIVRCKGILEAEGVEVDMKVLAALVKKNFPDFRRTINELQRYASTGKI---DA--GILSEVTNSDIDDVV 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 236 qTALKG-NFMEARELLDRLMVEYgmsgEDIVAQLFREIISMpIKDSLKVQLIDKLGEVDFRLTEGANERIQLDAYLAYLS 314
Cdd:PHA02544 237 -EALKAkDFKAVRALAPNYANDY----ASFVGKLYDELYPQ-VTPPSIIRLIEIIGENNQYHGFAADQEIHLLYLLTQLM 310
|
|
| PRK04195 |
PRK04195 |
replication factor C large subunit; Provisional |
7-248 |
2.54e-51 |
|
replication factor C large subunit; Provisional
Pssm-ID: 235250 [Multi-domain] Cd Length: 482 Bit Score: 176.26 E-value: 2.54e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 7 WVEKYRPRTLDEVVGQDEVIQRLKGYVER--KNIPH--LLFSGPPGTGKTATAIALARDLFGEnwrdnFIEMNASDERGI 82
Cdd:PRK04195 4 WVEKYRPKTLSDVVGNEKAKEQLREWIESwlKGKPKkaLLLYGPPGVGKTSLAHALANDYGWE-----VIELNASDQRTA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 83 DVVRHKIKEFARTAPIGGAPFKIIFLDEADAL--TADA--QAALRRTMemysKSCR--FILSCN-YVSRIIEPIQSRCAV 155
Cdd:PRK04195 79 DVIERVAGEAATSGSLFGARRKLILLDEVDGIhgNEDRggARAILELI----KKAKqpIILTANdPYDPSLRELRNACLM 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 156 FRFKPVPKEAMKKRLLEICEKEGVKITEDGLEALIYISGGDFRKAINALQGAAAIGEVVDADTIYQITATARPEEMTELI 235
Cdd:PRK04195 155 IEFKRLSTRSIVPVLKRICRKEGIECDDEALKEIAERSGGDLRSAINDLQAIAEGYGKLTLEDVKTLGRRDREESIFDAL 234
|
250
....*....|....
gi 499182012 236 QTALKG-NFMEARE 248
Cdd:PRK04195 235 DAVFKArNADQALE 248
|
|
| DnaX |
COG2812 |
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair]; |
13-273 |
3.33e-44 |
|
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
Pssm-ID: 442061 [Multi-domain] Cd Length: 340 Bit Score: 154.19 E-value: 3.33e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 13 PRTLDEVVGQDEVIQRLKGYVERKNIPH-LLFSGPPGTGKTATAIALARDLFGENWRD-------------------NFI 72
Cdd:COG2812 6 PQTFDDVVGQEHVVRTLKNALASGRLAHaYLFTGPRGVGKTTLARILAKALNCENGPTgepcgecescraiaagshpDVI 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 73 EM--NASdERGIDVVRhKIKEFARTAPIGGaPFKIIFLDEADALTADAQAALRRTME---MYSKscrFILSCNYVSRIIE 147
Cdd:COG2812 86 EIdaEAS-NIGVDDIR-ELIEKVSYAPVEG-RYKVYIIDEAHMLTTEAFNALLKTLEeppPHVV---FILATTEPQKLLP 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 148 PIQSRCAVFRFKPVPKEAMKKRLLEICEKEGVKITEDGLEALIYISGGDFRKAINALQGAAAIGevvdadtiyqitATAR 227
Cdd:COG2812 160 TILSRCQRFDFRRLPPEEIAEHLAKIAEREGIEIEPEALALIARAADGSMRDALSLLDQAIAFG------------LLDR 227
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 499182012 228 PEEMTELIQTALKGNFMEARELLDRLmVEYGMSGEDIVAQL---FREII 273
Cdd:COG2812 228 RELLLDLLEALLAGDVAALLALAEEL-AKRGRDLKRFLDDLlslLRDLL 275
|
|
| PRK14953 |
PRK14953 |
DNA polymerase III subunits gamma and tau; Provisional |
3-292 |
2.83e-38 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237867 [Multi-domain] Cd Length: 486 Bit Score: 141.50 E-value: 2.83e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 3 NFEIWVEKYRPRTLDEVVGQDEVIQRLKGYVERKNIPH-LLFSGPPGTGKTATAIALARDLFGENWRD------------ 69
Cdd:PRK14953 2 MYIPFARKYRPKFFKEVIGQEIVVRILKNAVKLQRVSHaYIFAGPRGTGKTTIARILAKVLNCLNPQEgepcgkcencve 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 70 -------NFIEMNASDERGIDVVRhKIKEFARTAPIGGApFKIIFLDEADALTADAQAALRRTMEMYSKSCRFILSCNYV 142
Cdd:PRK14953 82 idkgsfpDLIEIDAASNRGIDDIR-ALRDAVSYTPIKGK-YKVYIIDEAHMLTKEAFNALLKTLEEPPPRTIFILCTTEY 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 143 SRIIEPIQSRCAVFRFKPVPKEAMKKRLLEICEKEGVKITEDGLEALIYISGGDFRKAINALQGAAAIGE-VVDADTIYQ 221
Cdd:PRK14953 160 DKIPPTILSRCQRFIFSKPTKEQIKEYLKRICNEEKIEYEEKALDLLAQASEGGMRDAASLLDQASTYGEgKVTIKVVEE 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 499182012 222 ITATARPEEMTELIQTALKGNFMEARELLDRLMVEygmsGEDIVaqLFREIISMPIKDSLKVQLIDKLGEV 292
Cdd:PRK14953 240 FLGIVSQESVRKFLNLLLESDVDEAIKFLRTLEEK----GYNLN--KFWKQLEEEIRNILLNKSLKNPEEV 304
|
|
| PRK13342 |
PRK13342 |
recombination factor protein RarA; Reviewed |
9-222 |
3.36e-32 |
|
recombination factor protein RarA; Reviewed
Pssm-ID: 237355 [Multi-domain] Cd Length: 413 Bit Score: 123.66 E-value: 3.36e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 9 EKYRPRTLDEVVGQDEVIQR---LKGYVERKNIPHLLFSGPPGTGKTATAIALARDLfgenwRDNFIEMNASDErGIDVV 85
Cdd:PRK13342 4 ERMRPKTLDEVVGQEHLLGPgkpLRRMIEAGRLSSMILWGPPGTGKTTLARIIAGAT-----DAPFEALSAVTS-GVKDL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 86 RHKIKEFARTAPIGGAPfkIIFLDEADALTADAQAALRRTMEmyskSCRFIL----------ScnyvsrIIEPIQSRCAV 155
Cdd:PRK13342 78 REVIEEARQRRSAGRRT--ILFIDEIHRFNKAQQDALLPHVE----DGTITLigattenpsfE------VNPALLSRAQV 145
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 156 FRFKPVPKEAMK---KRLLEICEKEGVKITEDGLEALIYISGGDFRKAINALQGAAAIGEVVDADTIYQI 222
Cdd:PRK13342 146 FELKPLSEEDIEqllKRALEDKERGLVELDDEALDALARLANGDARRALNLLELAALGVDSITLELLEEA 215
|
|
| PRK14962 |
PRK14962 |
DNA polymerase III subunits gamma and tau; Provisional |
10-274 |
3.98e-31 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237869 [Multi-domain] Cd Length: 472 Bit Score: 121.80 E-value: 3.98e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 10 KYRPRTLDEVVGQDEVIQRLKGYVERKNIPH-LLFSGPPGTGKTATAIALARDLFGENWR--------------DN---- 70
Cdd:PRK14962 7 KYRPKTFSEVVGQDHVKKLIINALKKNSISHaYIFAGPRGTGKTTVARILAKSLNCENRKgvepcnecracrsiDEgtfm 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 71 -FIEMNASDERGIDVVRhKIKEFARTAPIGGApFKIIFLDEADALTADAQAALRRTMEMYSKSCRFILSCNYVSRIIEPI 149
Cdd:PRK14962 87 dVIELDAASNRGIDEIR-KIRDAVGYRPMEGK-YKVYIIDEVHMLTKEAFNALLKTLEEPPSHVVFVLATTNLEKVPPTI 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 150 QSRCAVFRFKPVPKEAMKKRLLEICEKEGVKITEDGLEALIYISGGDFRKAINAL-QGAAAIGEVVDADTIYQITATARP 228
Cdd:PRK14962 165 ISRCQVIEFRNISDELIIKRLQEVAEAEGIEIDREALSFIAKRASGGLRDALTMLeQVWKFSEGKITLETVHEALGLIPI 244
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 499182012 229 EEMTELIQTALKGNFMEARELLDRLMVEyGMSGEDIVAQLFREIIS 274
Cdd:PRK14962 245 EVVRDYINAIFNGDVKRVFTVLDDVYYS-GKDYEVLIQQAIEDLVE 289
|
|
| Rep_fac_C |
pfam08542 |
Replication factor C C-terminal domain; This is the C-terminal domain of RFC (replication ... |
226-311 |
1.62e-30 |
|
Replication factor C C-terminal domain; This is the C-terminal domain of RFC (replication factor-C) protein of the clamp loader complex which binds to the DNA sliding clamp (proliferating cell nuclear antigen, PCNA). The five modules of RFC assemble into a right-handed spiral, which results in only three of the five RFC subunits (RFC-A, RFC-B and RFC-C) making contact with PCNA, leaving a wedge-shaped gap between RFC-E and the PCNA clamp-loader complex. The C-terminal is vital for the correct orientation of RFC-E with respect to RFC-A.
Pssm-ID: 462513 [Multi-domain] Cd Length: 87 Bit Score: 110.64 E-value: 1.62e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 226 ARPEEMTELIQTALKGNFMEARELLDRLMVEYGMSGEDIVAQLFREIISMPIKDSLKVQLIDKLGEVDFRLTEGANERIQ 305
Cdd:pfam08542 1 PHPEDIEEILNSCLNGDFDEAYKKVRELLVEKGYSLQDIITQLHRVVKSLDLPEEVKLELLEKLGEIEYRLSEGASEKLQ 80
|
....*.
gi 499182012 306 LDAYLA 311
Cdd:pfam08542 81 LSALLA 86
|
|
| PRK07133 |
PRK07133 |
DNA polymerase III subunits gamma and tau; Validated |
3-253 |
2.67e-30 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235943 [Multi-domain] Cd Length: 725 Bit Score: 120.69 E-value: 2.67e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 3 NFEIWVEKYRPRTLDEVVGQDEVIQRLKGYVERKNIPH-LLFSGPPGTGKTATAIALA--------RDLFG------ENW 67
Cdd:PRK07133 4 KYKALYRKYRPKTFDDIVGQDHIVQTLKNIIKSNKISHaYLFSGPRGTGKTSVAKIFAnalncshkTDLLEpcqeciENV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 68 RDNF--IEMNASDERGIDVVRhKIKEFARTAPIGGaPFKIIFLDEADALTADAQAALRRTMEMYSKSCRFILSCNYVSRI 145
Cdd:PRK07133 84 NNSLdiIEMDAASNNGVDEIR-ELIENVKNLPTQS-KYKIYIIDEVHMLSKSAFNALLKTLEEPPKHVIFILATTEVHKI 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 146 IEPIQSRCAVFRFKPVPKEAMKKRLLEICEKEGVKITEDGLEALIYISGGDFRKAINALQGAAAIGE----VVDADTIYQ 221
Cdd:PRK07133 162 PLTILSRVQRFNFRRISEDEIVSRLEFILEKENISYEKNALKLIAKLSSGSLRDALSIAEQVSIFGNnkitLKNVEELFG 241
|
250 260 270
....*....|....*....|....*....|..
gi 499182012 222 ITATarpEEMTELIQTALKGNFMEARELLDRL 253
Cdd:PRK07133 242 LVSN---ENLINLLNLLYSKDIKEVLNILNQI 270
|
|
| PRK14970 |
PRK14970 |
DNA polymerase III subunits gamma and tau; Provisional |
1-237 |
6.42e-29 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184934 [Multi-domain] Cd Length: 367 Bit Score: 113.82 E-value: 6.42e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 1 MENFEIWVEKYRPRTLDEVVGQDEVIQRLKGYVERKNIPH-LLFSGPPGTGKTATAIALARDLFGENWRD-------NFI 72
Cdd:PRK14970 1 MENFVVSARKYRPQTFDDVVGQSHITNTLLNAIENNHLAQaLLFCGPRGVGKTTCARILARKINQPGYDDpnedfsfNIF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 73 EMNASDERGIDVVRHKIKEfARTAPIGGApFKIIFLDEADALTADAQAALRRTMEMYSKSCRFILSCNYVSRIIEPIQSR 152
Cdd:PRK14970 81 ELDAASNNSVDDIRNLIDQ-VRIPPQTGK-YKIYIIDEVHMLSSAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTILSR 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 153 CAVFRFKPVPKEAMKKRLLEICEKEGVKITEDGLEALIYISGGDFRKAIN-------------ALQGAAAIGEVVDADTI 219
Cdd:PRK14970 159 CQIFDFKRITIKDIKEHLAGIAVKEGIKFEDDALHIIAQKADGALRDALSifdrvvtfcgkniTRQAVTENLNILDYDTY 238
|
250
....*....|....*...
gi 499182012 220 YQITATARPEEMTELIQT 237
Cdd:PRK14970 239 INVTDLILENKIPELLLA 256
|
|
| PRK05563 |
PRK05563 |
DNA polymerase III subunits gamma and tau; Validated |
10-275 |
2.00e-28 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235505 [Multi-domain] Cd Length: 559 Bit Score: 114.97 E-value: 2.00e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 10 KYRPRTLDEVVGQDEVIQRLKGYVERKNIPH-LLFSGPPGTGKTATAIALARDLFGENWRD------------------- 69
Cdd:PRK05563 9 KWRPQTFEDVVGQEHITKTLKNAIKQGKISHaYLFSGPRGTGKTSAAKIFAKAVNCLNPPDgepcneceickaitngslm 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 70 NFIEMNASDERGIDVVRhKIKEFARTAPIGgAPFKIIFLDEADALTADAQAALRRTMEMYSKSCRFILSCNYVSRIIEPI 149
Cdd:PRK05563 89 DVIEIDAASNNGVDEIR-DIRDKVKYAPSE-AKYKVYIIDEVHMLSTGAFNALLKTLEEPPAHVIFILATTEPHKIPATI 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 150 QSRCAVFRFKPVPKEAMKKRLLEICEKEGVKITEDGLEALIYISGGDFRKAINALQGAAAIG-EVVDADTIYQITATARP 228
Cdd:PRK05563 167 LSRCQRFDFKRISVEDIVERLKYILDKEGIEYEDEALRLIARAAEGGMRDALSILDQAISFGdGKVTYEDALEVTGSVSQ 246
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 499182012 229 EEMTELIQTALKGNFMEARELLDRLMveygMSGEDIVaQLFREIISM 275
Cdd:PRK05563 247 EALDDLVDAIVEGDVAKALKILEELL----DEGKDPN-RFIEDLIYY 288
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
10-283 |
1.19e-26 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 109.90 E-value: 1.19e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 10 KYRPRTLDEVVGQDEVIQRLKGYVERKNIPH-LLFSGPPGTGKTATAIALARDL--------------------FGENWR 68
Cdd:PRK14950 9 KWRSQTFAELVGQEHVVQTLRNAIAEGRVAHaYLFTGPRGVGKTSTARILAKAVncttndpkgrpcgtcemcraIAEGSA 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 69 DNFIEMNASDERGIDVVRhKIKEFARTAPiGGAPFKIIFLDEADALTADAQAALRRTMEMYSKSCRFILSCNYVSRIIEP 148
Cdd:PRK14950 89 VDVIEMDAASHTSVDDAR-EIIERVQFRP-ALARYKVYIIDEVHMLSTAAFNALLKTLEEPPPHAIFILATTEVHKVPAT 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 149 IQSRCAVFRFKPVPKEAMKKRLLEICEKEGVKITEDGLEALIYISGGDFRKAINALQgaaaigevvdadtiyQITATARP 228
Cdd:PRK14950 167 ILSRCQRFDFHRHSVADMAAHLRKIAAAEGINLEPGALEAIARAATGSMRDAENLLQ---------------QLATTYGG 231
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 499182012 229 EEMTELIQTALkgnfmearelldrlmveyGMSGEDIVAQLFREIISMPIKDSLKV 283
Cdd:PRK14950 232 EISLSQVQSLL------------------GISGDEEVKALAEALLAKDLKAALRT 268
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
20-153 |
2.45e-26 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 101.84 E-value: 2.45e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 20 VGQDEVIQRLKGYVERKNIPHLLFSGPPGTGKTATAIALARDLFgeNWRDNFIEMNASDERGIDVVRHKIKEFARTAPIG 99
Cdd:cd00009 1 VGQEEAIEALREALELPPPKNLLLYGPPGTGKTTLARAIANELF--RPGAPFLYLNASDLLEGLVVAELFGHFLVRLLFE 78
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 499182012 100 ---GAPFKIIFLDEADALTADAQAALRRTMEMYSKS------CRFILSCNYVS--RIIEPIQSRC 153
Cdd:cd00009 79 laeKAKPGVLFIDEIDSLSRGAQNALLRVLETLNDLridrenVRVIGATNRPLlgDLDRALYDRL 143
|
|
| PRK05896 |
PRK05896 |
DNA polymerase III subunits gamma and tau; Validated |
9-291 |
7.57e-26 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235638 [Multi-domain] Cd Length: 605 Bit Score: 107.62 E-value: 7.57e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 9 EKYRPRTLDEVVGQDEVIQRLKGYVERKNIPH-LLFSGPPGTGKTATAIALARDLFGENWRD------------------ 69
Cdd:PRK05896 8 RKYRPHNFKQIIGQELIKKILVNAILNNKLTHaYIFSGPRGIGKTSIAKIFAKAINCLNPKDgdccnscsvcesintnqs 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 70 -NFIEMNASDERGIDVVRHKIKEfartapIGGAPF----KIIFLDEADALTADAQAALRRTMEMYSKSCRFILSCNYVSR 144
Cdd:PRK05896 88 vDIVELDAASNNGVDEIRNIIDN------INYLPTtfkyKVYIIDEAHMLSTSAWNALLKTLEEPPKHVVFIFATTEFQK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 145 IIEPIQSRCAVFRFKPVPKEAMKKRLLEICEKEGVKITEDGLEALIYISGGDFRKAINALQGAAAIGEV-VDADTIYQIT 223
Cdd:PRK05896 162 IPLTIISRCQRYNFKKLNNSELQELLKSIAKKEKIKIEDNAIDKIADLADGSLRDGLSILDQLSTFKNSeIDIEDINKTF 241
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 499182012 224 ATARPEEMTELIQTALKGNFMEARELLDRLMVeYGMSGEDIVAQLFREIISMPIKDSLK-VQLIDKLGE 291
Cdd:PRK05896 242 GLVDNNKKINLIELIQKNDIEELRNLINELES-KGINFEAFCRDLINLLIDLLVYQKTKnINLLKKLSK 309
|
|
| PRK14956 |
PRK14956 |
DNA polymerase III subunits gamma and tau; Provisional |
2-186 |
1.26e-24 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184920 [Multi-domain] Cd Length: 484 Bit Score: 103.49 E-value: 1.26e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 2 ENFEIWVEKYRPRTLDEVVGQDEVIQRLKGYVERKNIPH-LLFSGPPGTGKTATAIALARDLFGENWRDN---------- 70
Cdd:PRK14956 3 GTHEVLSRKYRPQFFRDVIHQDLAIGALQNALKSGKIGHaYIFFGPRGVGKTTIARILAKRLNCENPIGNepcnectscl 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 71 ---------FIEMNASDERGIDVVRhKIKEFARTAPIGGApFKIIFLDEADALTADAQAALRRTMEMYSKSCRFILSCNY 141
Cdd:PRK14956 83 eitkgissdVLEIDAASNRGIENIR-ELRDNVKFAPMGGK-YKVYIIDEVHMLTDQSFNALLKTLEEPPAHIVFILATTE 160
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 499182012 142 VSRIIEPIQSRCAVFRFKPVPKEAMKKRLLEICEKEGVKITEDGL 186
Cdd:PRK14956 161 FHKIPETILSRCQDFIFKKVPLSVLQDYSEKLCKIENVQYDQEGL 205
|
|
| PRK08451 |
PRK08451 |
DNA polymerase III subunits gamma and tau; Validated |
10-254 |
5.67e-24 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236267 [Multi-domain] Cd Length: 535 Bit Score: 102.03 E-value: 5.67e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 10 KYRPRTLDEVVGQDEVIQRLKGYVERKNIPH-LLFSGPPGTGKTATAIALARDLFGE-------------------NWRD 69
Cdd:PRK08451 7 KYRPKHFDELIGQESVSKTLSLALDNNRLAHaYLFSGLRGSGKTSSARIFARALVCEqgpsstpcdtciqcqsaleNRHI 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 70 NFIEMNASDERGIDVVRHKIkEFARTAPiGGAPFKIIFLDEADALTADAQAALRRTMEMYSKSCRFILSCNYVSRIIEPI 149
Cdd:PRK08451 87 DIIEMDAASNRGIDDIRELI-EQTKYKP-SMARFKIFIIDEVHMLTKEAFNALLKTLEEPPSYVKFILATTDPLKLPATI 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 150 QSRCAVFRFKPVPKEAMKKRLLEICEKEGVKITEDGLEALIYISGGDFR-------KAINALQGAAAIGEVVDA------ 216
Cdd:PRK08451 165 LSRTQHFRFKQIPQNSIISHLKTILEKEGVSYEPEALEILARSGNGSLRdtltlldQAIIYCKNAITESKVADMlglldp 244
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 499182012 217 ---DTIYQITATARPEEMTELIQTaLKGnfMEARELLDRLM 254
Cdd:PRK08451 245 sklEDFFQAILNQDKEKLFELLKE-LED--YEAEMVLDEMM 282
|
|
| PRK06647 |
PRK06647 |
DNA polymerase III subunits gamma and tau; Validated |
10-273 |
2.05e-23 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235845 [Multi-domain] Cd Length: 563 Bit Score: 100.23 E-value: 2.05e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 10 KYRPRTLDEVVGQDEVIQRLKGYVERKNIPH-LLFSGPPGTGKTATAIALARDLFGENW----------------RDN-- 70
Cdd:PRK06647 9 KRRPRDFNSLEGQDFVVETLKHSIESNKIANaYIFSGPRGVGKTSSARAFARCLNCVNGptpmpcgecsscksidNDNsl 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 71 -FIEMNASDERGIDVVRhKIKEFARTAPIGGApFKIIFLDEADALTADAQAALRRTMEMYSKSCRFILSCNYVSRIIEPI 149
Cdd:PRK06647 89 dVIEIDGASNTSVQDVR-QIKEEIMFPPASSR-YRVYIIDEVHMLSNSAFNALLKTIEEPPPYIVFIFATTEVHKLPATI 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 150 QSRCAVFRFKPVPKEAMKKRLLEICEKEGVKITEDGLEALIYISGGDFRKAINAL-QGAAAIGEVVDADTIYQITATARP 228
Cdd:PRK06647 167 KSRCQHFNFRLLSLEKIYNMLKKVCLEDQIKYEDEALKWIAYKSTGSVRDAYTLFdQVVSFSDSDITLEQIRSKMGLTGD 246
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 499182012 229 EEMTELIQTALKGNFMEARELLDRLMVEyGMSGEDIV---AQLFREII 273
Cdd:PRK06647 247 EFLEKLASSILNEDAKELLCVLDSVFLS-GVSVEQFLldcIEFFRELL 293
|
|
| PRK14948 |
PRK14948 |
DNA polymerase III subunit gamma/tau; |
10-252 |
2.06e-23 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237862 [Multi-domain] Cd Length: 620 Bit Score: 100.42 E-value: 2.06e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 10 KYRPRTLDEVVGQDEVIQRLKGYVERKNI-PHLLFSGPPGTGKTATAIALARDLfgenwrdN------------------ 70
Cdd:PRK14948 9 KYRPQRFDELVGQEAIATTLKNALISNRIaPAYLFTGPRGTGKTSSARILAKSL-------Nclnsdkptpepcgkcelc 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 71 ----------FIEMNASDERGIDVVRHKIkEFARTAPIgGAPFKIIFLDEADALTADAQAALRRTMEMYSKSCRFILSCN 140
Cdd:PRK14948 82 raiaagnaldVIEIDAASNTGVDNIRELI-ERAQFAPV-QARWKVYVIDECHMLSTAAFNALLKTLEEPPPRVVFVLATT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 141 YVSRIIEPIQSRCAVFRFKPVPKEAMKKRLLEICEKEGVKITEDGLEALIYISGGDFRKA------INALQG---AAAI- 210
Cdd:PRK14948 160 DPQRVLPTIISRCQRFDFRRIPLEAMVQHLSEIAEKESIEIEPEALTLVAQRSQGGLRDAeslldqLSLLPGpitPEAVw 239
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 499182012 211 ---GEVvdadtiyqitatarPE-EMTELIQtALKGNFMEA-----RELLDR 252
Cdd:PRK14948 240 dllGAV--------------PEqDLLNLLK-ALASNDPESlldscRQLLDR 275
|
|
| HLD_clamp_RFC |
cd18140 |
helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein ... |
161-223 |
3.72e-23 |
|
helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein clamp loader complex that forms a stable ATP-dependent complex with the sliding clamp, PCNA, which binds specifically to primed DNA. RFC subunits belong to the clamp loader clade of the AAA+ superfamily.
Pssm-ID: 350842 [Multi-domain] Cd Length: 63 Bit Score: 90.28 E-value: 3.72e-23
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 499182012 161 VPKEAMKKRLLEICEKEGVKITEDGLEALIYISGGDFRKAINALQGAAAIGEVVDADTIYQIT 223
Cdd:cd18140 1 LSKEQIVKRLREICKKEGVKIDEEALEAIAEKSEGDMRKAINDLQAAAAGGGVITEEDVYEVA 63
|
|
| PRK06305 |
PRK06305 |
DNA polymerase III subunits gamma and tau; Validated |
1-313 |
4.68e-23 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 180523 [Multi-domain] Cd Length: 451 Bit Score: 98.69 E-value: 4.68e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 1 MENFEIWVEKYRPRTLDEVVGQDEVIQRLKGYVERKNIPH-LLFSGPPGTGKTATAIALARDLFGENWRDNF-------- 71
Cdd:PRK06305 1 MTSYQVSSRKYRPQTFSEILGQDAVVAVLKNALRFNRAAHaYLFSGIRGTGKTTLARIFAKALNCQNPTEDQepcnqcas 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 72 ------------IEMNASDERGIDVVRhKIKEFARTAPIGGApFKIIFLDEADALTADAQAALRRTMEMYSKSCRFILSC 139
Cdd:PRK06305 81 ckeissgtsldvLEIDGASHRGIEDIR-QINETVLFTPSKSR-YKIYIIDEVHMLTKEAFNSLLKTLEEPPQHVKFFLAT 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 140 NYVSRIIEPIQSRCAVFRFKPVPKEAMKKRLLEICEKEGVKITEDGLEALIYISGGDFRKAINAL-QGAAAIGEVVDADT 218
Cdd:PRK06305 159 TEIHKIPGTILSRCQKMHLKRIPEETIIDKLALIAKQEGIETSREALLPIARAAQGSLRDAESLYdYVVGLFPKSLDPDS 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 219 IYQITATARPEEMTELIQTALKGNFMEARELLDRLMveygMSGEDIVA------QLFREI-----------ISMPIKDSL 281
Cdd:PRK06305 239 VAKALGLLSQDSLYTLDEAITTQNYAQALEPVTDAM----NSGVAPAHflhdltLFFRNIllkqynkqlssVATKYSSEQ 314
|
330 340 350
....*....|....*....|....*....|..
gi 499182012 282 KVQLIDKLGEVDFRLTEGANERIQLDAYLAYL 313
Cdd:PRK06305 315 LLEIIDFLGESAKHIQLTIFEKTFLETVIIHL 346
|
|
| PRK14965 |
PRK14965 |
DNA polymerase III subunits gamma and tau; Provisional |
3-217 |
9.40e-23 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237871 [Multi-domain] Cd Length: 576 Bit Score: 98.66 E-value: 9.40e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 3 NFEIWVEKYRPRTLDEVVGQDEVIQRLKGYVERKNIPH-LLFSGPPGTGKTATAIALARDLFGE---------------- 65
Cdd:PRK14965 2 SYLVLARKYRPQTFSDLTGQEHVSRTLQNAIDTGRVAHaFLFTGARGVGKTSTARILAKALNCEqgltaepcnvcppcve 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 66 ----NWRDNFiEMNASDERGIDVVRhKIKEFARTAPiGGAPFKIIFLDEADALTADAQAALRRTMEMYSKSCRFILSCNY 141
Cdd:PRK14965 82 itegRSVDVF-EIDGASNTGVDDIR-ELRENVKYLP-SRSRYKIFIIDEVHMLSTNAFNALLKTLEEPPPHVKFIFATTE 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 499182012 142 VSRIIEPIQSRCAVFRFKPVPKEAMKKRLLEICEKEGVKITEDGLeALIYISG-GDFRKAINAL-QGAAAIGEVVDAD 217
Cdd:PRK14965 159 PHKVPITILSRCQRFDFRRIPLQKIVDRLRYIADQEGISISDAAL-ALVARKGdGSMRDSLSTLdQVLAFCGDAVGDD 235
|
|
| PRK14964 |
PRK14964 |
DNA polymerase III subunits gamma and tau; Provisional |
10-208 |
2.76e-22 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237870 [Multi-domain] Cd Length: 491 Bit Score: 96.78 E-value: 2.76e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 10 KYRPRTLDEVVGQDEVIQRLKGYVERKNIPH-LLFSGPPGTGKTATA--IALARD-LFGENWR-----------DNF--- 71
Cdd:PRK14964 6 KYRPSSFKDLVGQDVLVRILRNAFTLNKIPQsILLVGASGVGKTTCAriISLCLNcSNGPTSDpcgtchncisiKNSnhp 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 72 --IEMNASDERGIDVVRhKIKEFARTAPIGgAPFKIIFLDEADALTADAQAALRRTMEMYSKSCRFILSCNYVSRIIEPI 149
Cdd:PRK14964 86 dvIEIDAASNTSVDDIK-VILENSCYLPIS-SKFKVYIIDEVHMLSNSAFNALLKTLEEPAPHVKFILATTEVKKIPVTI 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 499182012 150 QSRCAVFRFKPVPKEAMKKRLLEICEKEGVKITEDGLEALIYISGGDFRKAINALQGAA 208
Cdd:PRK14964 164 ISRCQRFDLQKIPTDKLVEHLVDIAKKENIEHDEESLKLIAENSSGSMRNALFLLEQAA 222
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
1-201 |
9.77e-22 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 95.61 E-value: 9.77e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 1 MENFEIWVEKYRPRTLDEVVGQDEVIQRLKGYVERKNIPH-LLFSGPPGTGKTATAIALARDL----------------- 62
Cdd:PRK14971 1 MENYIVSARKYRPSTFESVVGQEALTTTLKNAIATNKLAHaYLFCGPRGVGKTTCARIFAKTIncqnltadgeacneces 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 63 ---FGENWRDNFIEMNASDERGIDVVRHKIkEFARTAPIGGApFKIIFLDEADALTADAQAALRRTMEMYSKSCRFILSC 139
Cdd:PRK14971 81 cvaFNEQRSYNIHELDAASNNSVDDIRNLI-EQVRIPPQIGK-YKIYIIDEVHMLSQAAFNAFLKTLEEPPSYAIFILAT 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 499182012 140 NYVSRIIEPIQSRCAVFRFKPVPKEAMKKRLLEICEKEGVKITEDGLEALIYISGGDFRKAI 201
Cdd:PRK14971 159 TEKHKILPTILSRCQIFDFNRIQVADIVNHLQYVASKEGITAEPEALNVIAQKADGGMRDAL 220
|
|
| RarA |
COG2256 |
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, ... |
12-236 |
2.50e-21 |
|
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, recombination and repair];
Pssm-ID: 441857 [Multi-domain] Cd Length: 439 Bit Score: 93.58 E-value: 2.50e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 12 RPRTLDEVVGQDEV------IQRLkgyVERKNIPHLLFSGPPGTGKTATAIALARDLfgenwRDNFIEMNASDErGIDVV 85
Cdd:COG2256 20 RPRTLDEVVGQEHLlgpgkpLRRA---IEAGRLSSMILWGPPGTGKTTLARLIANAT-----DAEFVALSAVTS-GVKDI 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 86 RHKIKEfARTAPIGGAPFkIIFLDEADALTADAQAAL-----RRTmemyskscrFIL----------ScnyvsrIIEPIQ 150
Cdd:COG2256 91 REVIEE-ARERRAYGRRT-ILFVDEIHRFNKAQQDALlphveDGT---------ITLigattenpsfE------VNSALL 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 151 SRCAVFRFKPVPKEAMK---KRLLEICEK----EGVKITEDGLEALIYISGGDFRKAINALQGAAaigEVVDADTIYQIT 223
Cdd:COG2256 154 SRCRVFVLKPLSEEDLEqllERALADDERglggYKLELDDEALEALARLADGDARRALNALELAV---LSAPPDGVIEIT 230
|
250
....*....|...
gi 499182012 224 AtarpEEMTELIQ 236
Cdd:COG2256 231 L----ELVEEALQ 239
|
|
| PRK14963 |
PRK14963 |
DNA polymerase III subunits gamma and tau; Provisional |
9-200 |
4.12e-21 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184927 [Multi-domain] Cd Length: 504 Bit Score: 93.37 E-value: 4.12e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 9 EKYRPRTLDEVVGQDEVIQRLKGYVERKNIPH-LLFSGPPGTGKTATA--IALARDLFGENWRD---------------- 69
Cdd:PRK14963 6 QRARPITFDEVVGQEHVKEVLLAALRQGRLGHaYLFSGPRGVGKTTTArlIAMAVNCSGEDPKPcgecesclavrrgahp 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 70 NFIEMNASDERGIDVVRhKIKEFARTAPIGGaPFKIIFLDEADALTADAQAALRRTMEMYSKSCRFILSCNYVSRIIEPI 149
Cdd:PRK14963 86 DVLEIDAASNNSVEDVR-DLREKVLLAPLRG-GRKVYILDEAHMMSKSAFNALLKTLEEPPEHVIFILATTEPEKMPPTI 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 499182012 150 QSRCAVFRFKPVPKEAMKKRLLEICEKEGVKITEDGLEALIYISGGDFRKA 200
Cdd:PRK14963 164 LSRTQHFRFRRLTEEEIAGKLRRLLEAEGREAEPEALQLVARLADGAMRDA 214
|
|
| HLD_clamp |
cd18133 |
helical lid domain of clamp loader-like AAA+ proteins; Clamp loader complexes are multisubunit ... |
161-223 |
1.43e-20 |
|
helical lid domain of clamp loader-like AAA+ proteins; Clamp loader complexes are multisubunit complexes that play an important role in DNA replication. They open sliding clamps for assembly and close them around DNA, specifically targeting them to sites where DNA synthesis is initiated and orienting them correctly for replication. The subunits belong to the clamp loader clade of AAA+ superfamily.
Pssm-ID: 350838 [Multi-domain] Cd Length: 65 Bit Score: 83.67 E-value: 1.43e-20
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 499182012 161 VPKEAMKKRLLEICEKEGVKITEDGLEALIYISGGDFRKAINALQGAAAIGE--VVDADTIYQIT 223
Cdd:cd18133 1 LDQEQLKRRLAAIAEQEKLKLDDAALQALAYISEGDLRKALNALQRAAALGDdgKISLDRVYQAV 65
|
|
| PRK14969 |
PRK14969 |
DNA polymerase III subunits gamma and tau; Provisional |
10-249 |
1.61e-20 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237873 [Multi-domain] Cd Length: 527 Bit Score: 91.73 E-value: 1.61e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 10 KYRPRTLDEVVGQDEVIQRLKGYVERKNIPH-LLFSGPPGTGKTATAIALARDLFGENW----------------RDNF- 71
Cdd:PRK14969 9 KWRPKSFSELVGQEHVVRALTNALEQQRLHHaYLFTGTRGVGKTTLARILAKSLNCETGvtatpcgvcsacleidSGRFv 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 72 --IEMNASDERGIDVVRhKIKEFARTAPIGGApFKIIFLDEADALTADAQAALRRTMEMYSKSCRFILSCNYVSRIIEPI 149
Cdd:PRK14969 89 dlIEVDAASNTQVDAMR-ELLDNAQYAPTRGR-FKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPQKIPVTV 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 150 QSRCAVFRFKPVPKEAMKKRLLEICEKEGVKITEDGLEALIYISGGDFRKAINALQGAAAIGE-------------VVDA 216
Cdd:PRK14969 167 LSRCLQFNLKQMPPPLIVSHLQHILEQENIPFDATALQLLARAAAGSMRDALSLLDQAIAYGGgtvnesevramlgAIDQ 246
|
250 260 270
....*....|....*....|....*....|...
gi 499182012 217 DTIYQITATARPEEMTELIQTAlkgNFMEAREL 249
Cdd:PRK14969 247 DYLFALLEALLAQDGAALLAIA---DAMEERSL 276
|
|
| PRK08691 |
PRK08691 |
DNA polymerase III subunits gamma and tau; Validated |
4-236 |
1.07e-19 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236333 [Multi-domain] Cd Length: 709 Bit Score: 89.77 E-value: 1.07e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 4 FEIWVEKYRPRTLDEVVGQDEVIQRLKGYVERKNIPH-LLFSGPPGTGKTATAIALARDLFGENWRD------------- 69
Cdd:PRK08691 3 YQVLARKWRPKTFADLVGQEHVVKALQNALDEGRLHHaYLLTGTRGVGKTTIARILAKSLNCENAQHgepcgvcqsctqi 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 70 ------NFIEMNASDERGIDVVRhKIKEFARTAPIGGApFKIIFLDEADALTADAQAALRRTMEMYSKSCRFILSCNYVS 143
Cdd:PRK08691 83 dagryvDLLEIDAASNTGIDNIR-EVLENAQYAPTAGK-YKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPH 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 144 RIIEPIQSRCAVFRFKPVPKEAMKKRLLEICEKEGVKITEDGLEALIYISGGDFRKAINALQGAAAI--GEVVDADTIYQ 221
Cdd:PRK08691 161 KVPVTVLSRCLQFVLRNMTAQQVADHLAHVLDSEKIAYEPPALQLLGRAAAGSMRDALSLLDQAIALgsGKVAENDVRQM 240
|
250
....*....|....*
gi 499182012 222 ITATARpEEMTELIQ 236
Cdd:PRK08691 241 IGAVDK-QYLYELLT 254
|
|
| PRK14959 |
PRK14959 |
DNA polymerase III subunits gamma and tau; Provisional |
10-252 |
1.10e-19 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184923 [Multi-domain] Cd Length: 624 Bit Score: 89.35 E-value: 1.10e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 10 KYRPRTLDEVVGQDEVIQRL-KGYVERKNIPHLLFSGPPGTGKTATAIALARDL------------FGENWRD------- 69
Cdd:PRK14959 9 RYRPQTFAEVAGQETVKAILsRAAQENRVAPAYLFSGTRGVGKTTIARIFAKALncetaptgepcnTCEQCRKvtqgmhv 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 70 NFIEMNASDERGIDVVRhKIKEFARTAPIGGApFKIIFLDEADALTADAQAALRRTMEMYSKSCRFILSCNYVSRIIEPI 149
Cdd:PRK14959 89 DVVEIDGASNRGIDDAK-RLKEAIGYAPMEGR-YKVFIIDEAHMLTREAFNALLKTLEEPPARVTFVLATTEPHKFPVTI 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 150 QSRCAVFRFKPVPKEAMKKRLLEICEKEGVKITEDGLEALIYISGGDFRKAINALQGAAAIGEV-VDADTIYQITATARP 228
Cdd:PRK14959 167 VSRCQHFTFTRLSEAGLEAHLTKVLGREGVDYDPAAVRLIARRAAGSVRDSMSLLGQVLALGESrLTIDGARGVLGLAGQ 246
|
250 260
....*....|....*....|....*...
gi 499182012 229 EEMTELIQTALKGNFME----ARELLDR 252
Cdd:PRK14959 247 ELFLRLMEALAAQDCLGvanvVRELLDR 274
|
|
| PRK14961 |
PRK14961 |
DNA polymerase III subunits gamma and tau; Provisional |
3-212 |
1.93e-19 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184925 [Multi-domain] Cd Length: 363 Bit Score: 87.56 E-value: 1.93e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 3 NFEIWVEKYRPRTLDEVVGQDEVIQRLKGYVERKNIPHL-LFSGPPGTGKTATAIALARDLFGE------------NWRD 69
Cdd:PRK14961 2 NYQILARKWRPQYFRDIIGQKHIVTAISNGLSLGRIHHAwLLSGTRGVGKTTIARLLAKSLNCQngitsnpcrkciICKE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 70 -------NFIEMNASDERGIDVVRhKIKEFARTAPIGGApFKIIFLDEADALTADAQAALRRTMEMYSKSCRFILSCNYV 142
Cdd:PRK14961 82 iekglclDLIEIDAASRTKVEEMR-EILDNIYYSPSKSR-FKVYLIDEVHMLSRHSFNALLKTLEEPPQHIKFILATTDV 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 143 SRIIEPIQSRCAVFRFKPVPKEAMKKRLLEICEKEGVKITEDGLEALIYISGGDFRKAINALQGAAAIGE 212
Cdd:PRK14961 160 EKIPKTILSRCLQFKLKIISEEKIFNFLKYILIKESIDTDEYALKLIAYHAHGSMRDALNLLEHAINLGK 229
|
|
| PRK14952 |
PRK14952 |
DNA polymerase III subunits gamma/tau; |
10-195 |
5.74e-19 |
|
DNA polymerase III subunits gamma/tau;
Pssm-ID: 237866 [Multi-domain] Cd Length: 584 Bit Score: 87.24 E-value: 5.74e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 10 KYRPRTLDEVVGQDEVIQRLKGYVERKNIPH-LLFSGPPGTGKTATAIALARDL-------------------FGENWRD 69
Cdd:PRK14952 6 KYRPATFAEVVGQEHVTEPLSSALDAGRINHaYLFSGPRGCGKTSSARILARSLncaqgptatpcgvcescvaLAPNGPG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 70 NF--IEMNASDERGIDVVRhKIKEFARTAPiGGAPFKIIFLDEADALTADAQAALRRTMEMYSKSCRFILSCNYVSRIIE 147
Cdd:PRK14952 86 SIdvVELDAASHGGVDDTR-ELRDRAFYAP-AQSRYRIFIVDEAHMVTTAGFNALLKIVEEPPEHLIFIFATTEPEKVLP 163
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 499182012 148 PIQSRCAVFRFKPVPKEAMKKRLLEICEKEGVKItEDGLEALIYISGG 195
Cdd:PRK14952 164 TIRSRTHHYPFRLLPPRTMRALIARICEQEGVVV-DDAVYPLVIRAGG 210
|
|
| AAA |
pfam00004 |
ATPase family associated with various cellular activities (AAA); AAA family proteins often ... |
41-161 |
7.31e-19 |
|
ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.
Pssm-ID: 459627 [Multi-domain] Cd Length: 130 Bit Score: 81.10 E-value: 7.31e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 41 LLFSGPPGTGKTATAIALARDLFGenwrdNFIEMNASDERG--IDVVRHKIKEFARTAPIGGAPfkIIFLDEADAL---- 114
Cdd:pfam00004 1 LLLYGPPGTGKTTLAKAVAKELGA-----PFIEISGSELVSkyVGESEKRLRELFEAAKKLAPC--VIFIDEIDALagsr 73
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 499182012 115 -------TADAQAALRRTMEMYSKSCR---FILSCNYVSRIIEPIQSRCAVFRFKPV 161
Cdd:pfam00004 74 gsggdseSRRVVNQLLTELDGFTSSNSkviVIAATNRPDKLDPALLGRFDRIIEFPL 130
|
|
| PRK04132 |
PRK04132 |
replication factor C small subunit; Provisional |
7-54 |
8.84e-18 |
|
replication factor C small subunit; Provisional
Pssm-ID: 235223 [Multi-domain] Cd Length: 846 Bit Score: 84.12 E-value: 8.84e-18
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 499182012 7 WVEKYRPRTLDEVVGQDEVIQRLKGYVERKNIPHLLFSGPPGTGKTAT 54
Cdd:PRK04132 9 WVEKYRPQRLDDIVGQEHIVKRLKHYVKTGSMPHLLFAGPPGVGKCLT 56
|
|
| PRK14957 |
PRK14957 |
DNA polymerase III subunits gamma and tau; Provisional |
3-319 |
1.52e-17 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184921 [Multi-domain] Cd Length: 546 Bit Score: 83.21 E-value: 1.52e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 3 NFEIWVEKYRPRTLDEVVGQDEVIQRLKGYVERKNIPH-LLFSGPPGTGKTATAIALARDL------------------- 62
Cdd:PRK14957 2 SYQALARKYRPQSFAEVAGQQHALNSLVHALETQKVHHaYLFTGTRGVGKTTLGRLLAKCLncktgvtaepcnkcencva 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 63 FGENWRDNFIEMNASDERGIDVVRhKIKEFARTAPIGGApFKIIFLDEADALTADAQAALRRTMEMYSKSCRFILSCNYV 142
Cdd:PRK14957 82 INNNSFIDLIEIDAASRTGVEETK-EILDNIQYMPSQGR-YKVYLIDEVHMLSKQSFNALLKTLEEPPEYVKFILATTDY 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 143 SRIIEPIQSRCAVFRFKPVPKEAMKKRLLEICEKEGVKITEDGLEALIYISGGDFRKAINALQGAAAI--GEVVDADtIY 220
Cdd:PRK14957 160 HKIPVTILSRCIQLHLKHISQADIKDQLKIILAKENINSDEQSLEYIAYHAKGSLRDALSLLDQAISFcgGELKQAQ-IK 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 221 QITATARPEEMTELIQTALKGNFMEARELLDRLMVEygMSGEDIVAQLFREIISMPIKDSLkVQLIDKLGEVDFRLTEGA 300
Cdd:PRK14957 239 QMLGIIDSEEVYSIINAIIDNDPKAILPAIKNLALT--ESSADAVLDRIAEIWFACCIYSF-TQSLDAVNDIDVDIINNI 315
|
330 340
....*....|....*....|.
gi 499182012 301 NERIQLDA--YLAYLSTLAKK 319
Cdd:PRK14957 316 LAKISIEQahFLYQLTITAKK 336
|
|
| PRK14960 |
PRK14960 |
DNA polymerase III subunit gamma/tau; |
4-212 |
2.30e-17 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237868 [Multi-domain] Cd Length: 702 Bit Score: 82.79 E-value: 2.30e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 4 FEIWVEKYRPRTLDEVVGQDEVIQRLKGYVERKNIPH-LLFSGPPGTGKTATAIALARDL-------------------F 63
Cdd:PRK14960 2 YQVLARKYRPRNFNELVGQNHVSRALSSALERGRLHHaYLFTGTRGVGKTTIARILAKCLncetgvtstpcevcatckaV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 64 GENWRDNFIEMNASDERGIDVVRHKIKEFArTAPIGGApFKIIFLDEADALTADAQAALRRTMEMYSKSCRFILSCNYVS 143
Cdd:PRK14960 82 NEGRFIDLIEIDAASRTKVEDTRELLDNVP-YAPTQGR-FKVYLIDEVHMLSTHSFNALLKTLEEPPEHVKFLFATTDPQ 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 499182012 144 RIIEPIQSRCAVFRFKPVPKEAMKKRLLEICEKEGVKITEDGLEALIYISGGDFRKAINALQGAAAIGE 212
Cdd:PRK14960 160 KLPITVISRCLQFTLRPLAVDEITKHLGAILEKEQIAADQDAIWQIAESAQGSLRDALSLTDQAIAYGQ 228
|
|
| PRK14955 |
PRK14955 |
DNA polymerase III subunits gamma and tau; Provisional |
3-254 |
2.52e-17 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184919 [Multi-domain] Cd Length: 397 Bit Score: 81.86 E-value: 2.52e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 3 NFEIWVEKYRPRTLDEVVGQDEVIQRLKGYVERKNIPH-LLFSGPPGTGKTATAIALARDLFG----------------- 64
Cdd:PRK14955 2 SYQVIARKYRPKKFADITAQEHITRTIQNSLRMGRVGHgYIFSGLRGVGKTTAARVFAKAVNCqrmiddadylqevtepc 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 65 ---ENWRD-------NFIEMNASDERGIDVVRhKIKEFARTAPIGGApFKIIFLDEADALTADAQAALRRTMEMYSKSCR 134
Cdd:PRK14955 82 gecESCRDfdagtslNISEFDAASNNSVDDIR-LLRENVRYGPQKGR-YRVYIIDEVHMLSIAAFNAFLKTLEEPPPHAI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 135 FILSCNYVSRIIEPIQSRCAVFRFKPVPKEAMKKRLLEICEKEGVKITEDGLEALIYISGGDFRKAINAL---------- 204
Cdd:PRK14955 160 FIFATTELHKIPATIASRCQRFNFKRIPLEEIQQQLQGICEAEGISVDADALQLIGRKAQGSMRDAQSILdqviafsves 239
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 499182012 205 --------QGAAAIGEVVDADTIYQIT---ATARPEEMTELIQTALKGNFMEaRELLDRLM 254
Cdd:PRK14955 240 egegsiryDKVAELLNYIDDEHFFAVTdavADGDAVAMLDVAQFVIRNGYDE-QDFLEKLI 299
|
|
| DNA_pol3_delta2 |
pfam13177 |
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ... |
21-162 |
8.33e-17 |
|
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.
Pssm-ID: 433013 [Multi-domain] Cd Length: 161 Bit Score: 76.48 E-value: 8.33e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 21 GQDEVIQRLKGYVERKNIPH-LLFSGPPGTGKTATAIALARDLFGENWRDN-----------FIEMNASD---------E 79
Cdd:pfam13177 1 GQPEAIQLLQNSLENGRLSHaYLFSGPEGVGKLELALAFAKALFCEEPGDDlpcgqcrscrrIESGNHPDlviiepegqS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 80 RGIDVVRHKIKEFARTaPIGGaPFKIIFLDEADALTADAQAALRRTMEMYSKSCRFILSCNYVSRIIEPIQSRCAVFRFK 159
Cdd:pfam13177 81 IKIDQIRELQKEFSKS-PYEG-KKKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPTIRSRCQIIRFK 158
|
...
gi 499182012 160 PVP 162
Cdd:pfam13177 159 PLS 161
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
10-216 |
1.34e-16 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 80.31 E-value: 1.34e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 10 KYRPRTLDEVVGQDEVIQRLKGYVERKNIPH-LLFSGPPGTGKTATAIALARDL-----FGEN----------------- 66
Cdd:PRK12323 9 KWRPRDFTTLVGQEHVVRALTHALEQQRLHHaYLFTGTRGVGKTTLSRILAKSLnctgaDGEGgitaqpcgqcracteid 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 67 ---WRDnFIEMNASDERGIDVVRhKIKEFARTAPIGGApFKIIFLDEADALTADAQAALRRTMEMYSKSCRFILSCNYVS 143
Cdd:PRK12323 89 agrFVD-YIEMDAASNRGVDEMA-QLLDKAVYAPTAGR-FKVYMIDEVHMLTNHAFNAMLKTLEEPPEHVKFILATTDPQ 165
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 499182012 144 RIIEPIQSRCAVFRFKPVPKEAMKKRLLEICEKEGVKITEDGLEALIYISGGDFRKAINALQGAAA--IGEVVDA 216
Cdd:PRK12323 166 KIPVTVLSRCLQFNLKQMPPGHIVSHLDAILGEEGIAHEVNALRLLAQAAQGSMRDALSLTDQAIAysAGNVSEE 240
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
10-211 |
1.60e-16 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 80.14 E-value: 1.60e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 10 KYRPRTLDEVVGQDEVIQRLKGYVERKNIPH-LLFSGPPGTGKTATAIALARDL-----------------FGENWRD-- 69
Cdd:PRK14951 9 KYRPRSFSEMVGQEHVVQALTNALTQQRLHHaYLFTGTRGVGKTTVSRILAKSLncqgpdgqggitatpcgVCQACRDid 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 70 -----NFIEMNASDERGIDVVRhKIKEFARTAPIGGApFKIIFLDEADALTADAQAALRRTMEMYSKSCRFILSCNYVSR 144
Cdd:PRK14951 89 sgrfvDYTELDAASNRGVDEVQ-QLLEQAVYKPVQGR-FKVFMIDEVHMLTNTAFNAMLKTLEEPPEYLKFVLATTDPQK 166
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 499182012 145 IIEPIQSRCAVFRFKPVPKEAMKKRLLEICEKEGVKITEDGLEALIYISGGDFRKAINALQGAAAIG 211
Cdd:PRK14951 167 VPVTVLSRCLQFNLRPMAPETVLEHLTQVLAAENVPAEPQALRLLARAARGSMRDALSLTDQAIAFG 233
|
|
| PRK09111 |
PRK09111 |
DNA polymerase III subunits gamma and tau; Validated |
10-190 |
5.07e-16 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236382 [Multi-domain] Cd Length: 598 Bit Score: 78.40 E-value: 5.07e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 10 KYRPRTLDEVVGQDEVIQRLKGYVERKNIPH-LLFSGPPGTGKTATAIALARDL-----------------FGENWRD-- 69
Cdd:PRK09111 17 KYRPQTFDDLIGQEAMVRTLTNAFETGRIAQaFMLTGVRGVGKTTTARILARALnyegpdgdggptidlcgVGEHCQAim 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 70 -----NFIEMNASDERGIDVVRhKIKEFARTAPIgGAPFKIIFLDEADALTADAQAALRRTMEMYSKSCRFILSCNYVSR 144
Cdd:PRK09111 97 egrhvDVLEMDAASHTGVDDIR-EIIESVRYRPV-SARYKVYIIDEVHMLSTAAFNALLKTLEEPPPHVKFIFATTEIRK 174
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 499182012 145 IIEPIQSRCAVFRFKPVPKEAMKKRLLEICEKEGVKITEDGLeALI 190
Cdd:PRK09111 175 VPVTVLSRCQRFDLRRIEADVLAAHLSRIAAKEGVEVEDEAL-ALI 219
|
|
| PRK06645 |
PRK06645 |
DNA polymerase III subunits gamma and tau; Validated |
3-287 |
7.26e-16 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 180643 [Multi-domain] Cd Length: 507 Bit Score: 77.98 E-value: 7.26e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 3 NFEIWVEKYRPRTLDEVVGQdEVIQRLKGY--VERKNIPHLLFSGPPGTGKTATAIALARDL------------------ 62
Cdd:PRK06645 7 QYIPFARKYRPSNFAELQGQ-EVLVKVLSYtiLNDRLAGGYLLTGIRGVGKTTSARIIAKAVncsalitenttiktceqc 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 63 -----FGENWRDNFIEMNASDERGIDVVRhKIKEFARTAPIGGApFKIIFLDEADALTADAQAALRRTMEMYSKSCRFIL 137
Cdd:PRK06645 86 tncisFNNHNHPDIIEIDAASKTSVDDIR-RIIESAEYKPLQGK-HKIFIIDEVHMLSKGAFNALLKTLEEPPPHIIFIF 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 138 SCNYVSRIIEPIQSRCAVFRFKPVPKEAMKKRLLEICEKEGVKITEDGLEALIYISGGDFRKAINALQGAAA----IGEV 213
Cdd:PRK06645 164 ATTEVQKIPATIISRCQRYDLRRLSFEEIFKLLEYITKQENLKTDIEALRIIAYKSEGSARDAVSILDQAASmsakSDNI 243
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 499182012 214 VDADTIYQITATARPEEMTELIQTALKGNFMEARELLDRLmveYGMSgedIVAQLFREIISMPIKDSLKVQLID 287
Cdd:PRK06645 244 ISPQVINQMLGLVDSSVIIEFVEYIIHRETEKAINLINKL---YGSS---VNLEIFIESVSDFIAYLNKVKMLP 311
|
|
| PRK13341 |
PRK13341 |
AAA family ATPase; |
9-229 |
1.13e-15 |
|
AAA family ATPase;
Pssm-ID: 237354 [Multi-domain] Cd Length: 725 Bit Score: 77.40 E-value: 1.13e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 9 EKYRPRTLDEVVGQDEVI---QRLKGYVERKNIPHLLFSGPPGTGKTATAIALARdlfgeNWRDNFIEMNA-----SDER 80
Cdd:PRK13341 20 DRLRPRTLEEFVGQDHILgegRLLRRAIKADRVGSLILYGPPGVGKTTLARIIAN-----HTRAHFSSLNAvlagvKDLR 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 81 G-IDVVRHKIKEFA-RTapiggapfkIIFLDEADALTADAQAAL-----RRTMEMYSKSCRfilscNYVSRIIEPIQSRC 153
Cdd:PRK13341 95 AeVDRAKERLERHGkRT---------ILFIDEVHRFNKAQQDALlpwveNGTITLIGATTE-----NPYFEVNKALVSRS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 154 AVFRFKPVPKEAMKK---RLLEICE----KEGVKITEDGLEALIYISGGDFRKAINALQGAAAIGEvVDADTIYQITATA 226
Cdd:PRK13341 161 RLFRLKSLSDEDLHQllkRALQDKErgygDRKVDLEPEAEKHLVDVANGDARSLLNALELAVESTP-PDEDGLIDITLAI 239
|
...
gi 499182012 227 RPE 229
Cdd:PRK13341 240 AEE 242
|
|
| PRK14954 |
PRK14954 |
DNA polymerase III subunits gamma and tau; Provisional |
3-254 |
1.29e-15 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184918 [Multi-domain] Cd Length: 620 Bit Score: 77.29 E-value: 1.29e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 3 NFEIWVEKYRPRTLDEVVGQDEVIQRLKGYVERKNIPH-LLFSGPPGTGKTATAIALARDL------------------- 62
Cdd:PRK14954 2 SYQVIARKYRPSKFADITAQEHITHTIQNSLRMDRVGHgYIFSGLRGVGKTTAARVFAKAVncqrmiddpvylqevtepc 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 63 -FGENWRD-------NFIEMNASDERGIDVVRhKIKEFARTAPIGGApFKIIFLDEADALTADAQAALRRTMEMYSKSCR 134
Cdd:PRK14954 82 gECESCRDfdagtslNISEFDAASNNSVDDIR-QLRENVRYGPQKGR-YRVYIIDEVHMLSTAAFNAFLKTLEEPPPHAI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 135 FILSCNYVSRIIEPIQSRCAVFRFKPVPKEAMKKRLLEICEKEGVKITEDGLEALIYISGGDFRKAINAL---------- 204
Cdd:PRK14954 160 FIFATTELHKIPATIASRCQRFNFKRIPLDEIQSQLQMICRAEGIQIDADALQLIARKAQGSMRDAQSILdqviafsvgs 239
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 499182012 205 --------QGAAAIGEVVDADTIYQIT---ATARPEEMTELIQTALKGNFMEaRELLDRLM 254
Cdd:PRK14954 240 eaekviayQGVAELLNYIDDEQFFDVTdaiAENDAVKMLEVARFVIDNGYDE-QDFLEKLI 299
|
|
| PRK14958 |
PRK14958 |
DNA polymerase III subunits gamma and tau; Provisional |
5-291 |
3.72e-14 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184922 [Multi-domain] Cd Length: 509 Bit Score: 72.84 E-value: 3.72e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 5 EIWVEKYRPRTLDEVVGQDEVIQRLKGYVERKNIPH-LLFSGPPGTGKTATAIALARDLFGE------------NWRD-- 69
Cdd:PRK14958 4 QVLARKWRPRCFQEVIGQAPVVRALSNALDQQYLHHaYLFTGTRGVGKTTISRILAKCLNCEkgvsanpcndceNCREid 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 70 -----NFIEMNASDERGIDVVRHKIKEFArTAPIGGApFKIIFLDEADALTADAQAALRRTMEMYSKSCRFILSCNYVSR 144
Cdd:PRK14958 84 egrfpDLFEVDAASRTKVEDTRELLDNIP-YAPTKGR-FKVYLIDEVHMLSGHSFNALLKTLEEPPSHVKFILATTDHHK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 145 IIEPIQSRCAVFRFKPVPKEAMKKRLLEICEKEGVKITEDGLEALIYISGGDFRKAINALQGAAAI--GEVVDADTiyqi 222
Cdd:PRK14958 162 LPVTVLSRCLQFHLAQLPPLQIAAHCQHLLKEENVEFENAALDLLARAANGSVRDALSLLDQSIAYgnGKVLIADV---- 237
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 499182012 223 tatarpEEMTELIQTALKGNFME--ARELLDRL------MVEYGMSGEDIVAQLFREIISMPIKDSLKVQLIDKLGE 291
Cdd:PRK14958 238 ------KTMLGTIEPLLLFDILEalAAKAGDRLlgcvtrLVEQGVDFSNALADLLSLLHQIAIIQTVPEALIENDSE 308
|
|
| PRK05564 |
PRK05564 |
DNA polymerase III subunit delta'; Validated |
18-195 |
3.90e-14 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 180132 [Multi-domain] Cd Length: 313 Bit Score: 71.60 E-value: 3.90e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 18 EVVGQDEVIQRLKGYVERKNIPHL-LFSGPPGTGKTATAIALARDLFGENWRDNF---IEMNASDER--GIDVVRHKIKE 91
Cdd:PRK05564 5 TIIGHENIKNRIKNSIIKNRFSHAhIIVGEDGIGKSLLAKEIALKILGKSQQREYvdiIEFKPINKKsiGVDDIRNIIEE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 92 fartapIGGAPF----KIIFLDEADALTADAQAALRRTMEMYSKSCRFILSCNYVSRIIEPIQSRCAVFRFKPVPKEAMK 167
Cdd:PRK05564 85 ------VNKKPYegdkKVIIIYNSEKMTEQAQNAFLKTIEEPPKGVFIILLCENLEQILDTIKSRCQIYKLNRLSKEEIE 158
|
170 180
....*....|....*....|....*...
gi 499182012 168 KRLleicEKEGVKITEDGLEALIYISGG 195
Cdd:PRK05564 159 KFI----SYKYNDIKEEEKKSAIAFSDG 182
|
|
| rad24 |
TIGR00602 |
checkpoint protein rad24; All proteins in this family for which functions are known are ... |
4-205 |
5.38e-12 |
|
checkpoint protein rad24; All proteins in this family for which functions are known are involved in DNA damage tolerance (likely cell cycle checkpoints).This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129690 [Multi-domain] Cd Length: 637 Bit Score: 66.52 E-value: 5.38e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 4 FEIWVEKYRPRTLDEVVGQ----DEVIQRLKGYV-ERKNIPHLLFSGPPGTGKTATAIALARDLfGENWRDNFIEMN--- 75
Cdd:TIGR00602 71 NEPWVEKYKPETQHELAVHkkkiEEVETWLKAQVlENAPKRILLITGPSGCGKSTTIKILSKEL-GIQVQEWSNPTLpdf 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 76 -ASDERGIDVVRHKI----------KEFARTAPIGG--------APFKIIFLDEADA---LTADAQAALRRTMEMYSKSC 133
Cdd:TIGR00602 150 qKNDHKVTLSLESCFsnfqsqievfSEFLLRATNKLqmlgddlmTDKKIILVEDLPNqfyRDTRALHEILRWKYVSIGRC 229
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 134 RFI---------------LSCNYVSRIIEPIQSRCAVFR--FKPVPKEAMKKRLLEICEKEGVKITE-------DGLEAL 189
Cdd:TIGR00602 230 PLVfiiteslegdnnqrrLLFPAETIMNKEILEEPRVSNisFNPIAPTIMKKFLNRIVTIEAKKNGEkikvpkkTSVELL 309
|
250
....*....|....*.
gi 499182012 190 IYISGGDFRKAINALQ 205
Cdd:TIGR00602 310 CQGCSGDIRSAINSLQ 325
|
|
| PRK07399 |
PRK07399 |
DNA polymerase III subunit delta'; Validated |
17-249 |
1.24e-11 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 236011 [Multi-domain] Cd Length: 314 Bit Score: 64.15 E-value: 1.24e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 17 DEVVGQDEVIQRLKGYVERKNI-PHLLFSGPPGTGKTATAIALARDLF-----GENWRDNFIEMNASD------------ 78
Cdd:PRK07399 4 ANLIGQPLAIELLTAAIKQNRIaPAYLFAGPEGVGRKLAALCFIEGLLsqgspSKNIRRRLEEGNHPDllwveptyqhqg 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 79 --------------ERGIDVVR----HKIKEFARTAPIGgAPFKIIFLDEADALTADAQAALRRTMEMySKSCRFILSCN 140
Cdd:PRK07399 84 klitaseaeeaglkRKAPPQIRleqiREIKRFLSRPPLE-APRKVVVIEDAETMNEAAANALLKTLEE-PGNGTLILIAP 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 141 YVSRIIEPIQSRCAVFRFKPVPKEAMKKRLLEICEKEGVKITedgLEALIYISGGDFRKAINALQGAAAIgevvdadtiy 220
Cdd:PRK07399 162 SPESLLPTIVSRCQIIPFYRLSDEQLEQVLKRLGDEEILNIN---FPELLALAQGSPGAAIANIEQLQSI---------- 228
|
250 260
....*....|....*....|....*....
gi 499182012 221 qitatarPEEMTELIQTALKgNFMEAREL 249
Cdd:PRK07399 229 -------PPELLQKLEQPPK-SPLEALEL 249
|
|
| PRK08058 |
PRK08058 |
DNA polymerase III subunit delta'; Validated |
22-179 |
1.81e-11 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 181214 [Multi-domain] Cd Length: 329 Bit Score: 63.79 E-value: 1.81e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 22 QDEVIQRLKGYVERKNIPH-LLFSGPPGTGKTATAIALARDLFGENWRDNF----------IEMN--------ASDERGI 82
Cdd:PRK08058 11 QPVVVKMLQNSIAKNRLSHaYLFEGAKGTGKKATALWLAKSLFCLERNGVEpcgtctnckrIDSGnhpdvhlvAPDGQSI 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 83 DV--VRHKIKEFARTAPIGGApfKIIFLDEADALTADAQAALRRTMEMYSKSCRFILSCNYVSRIIEPIQSRCAVFRFKP 160
Cdd:PRK08058 91 KKdqIRYLKEEFSKSGVESNK--KVYIIEHADKMTASAANSLLKFLEEPSGGTTAILLTENKHQILPTILSRCQVVEFRP 168
|
170
....*....|....*....
gi 499182012 161 VPKEAMKKRLleicEKEGV 179
Cdd:PRK08058 169 LPPESLIQRL----QEEGI 183
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
10-185 |
1.85e-11 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 65.01 E-value: 1.85e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 10 KYRPRTLDEVVGQDEVIQRLKGYVeRKN-IPH-LLFSGPPGTGKTATAIALARDLfgenwrdN----------------- 70
Cdd:PRK07764 8 RYRPATFAEVIGQEHVTEPLSTAL-DSGrINHaYLFSGPRGCGKTSSARILARSL-------Ncvegptstpcgecdscv 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 71 -----------FIEMNASDERGIDVVRhKIKEFARTAPIgGAPFKIIFLDEADALTADAQAALRRTMEMYSKSCRFILSC 139
Cdd:PRK07764 80 alapggpgsldVTEIDAASHGGVDDAR-ELRERAFFAPA-ESRYKIFIIDEAHMVTPQGFNALLKIVEEPPEHLKFIFAT 157
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 499182012 140 NYVSRIIEPIQSRCAVFRFKPVPKEAMKKRLLEICEKEGVKItEDG 185
Cdd:PRK07764 158 TEPDKVIGTIRSRTHHYPFRLVPPEVMRGYLERICAQEGVPV-EPG 202
|
|
| SpoVK |
COG0464 |
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ... |
5-219 |
4.07e-11 |
|
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 440232 [Multi-domain] Cd Length: 397 Bit Score: 63.39 E-value: 4.07e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 5 EIWVEKYRPRTLDEVVGQDEVIQRLKGYV----------ERKNIP---HLLFSGPPGTGKTATAIALARDlfgenWRDNF 71
Cdd:COG0464 145 EEELLELREAILDDLGGLEEVKEELRELValplkrpelrEEYGLPpprGLLLYGPPGTGKTLLARALAGE-----LGLPL 219
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 72 IEMNASD---------ERGIdvvRHKIKEFARTAPIggapfkIIFLDEADALTADAQAALRRT-----------MEMYSK 131
Cdd:COG0464 220 IEVDLSDlvskyvgetEKNL---REVFDKARGLAPC------VLFIDEADALAGKRGEVGDGVgrrvvntllteMEELRS 290
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 132 SCRFILSCNYVSRIIEPIQSRCA-VFRFkPVPKEAMKKRLLEICEKEgVKITEDG-LEALIYI----SGGDFRKAIN--A 203
Cdd:COG0464 291 DVVVIAATNRPDLLDPALLRRFDeIIFF-PLPDAEERLEIFRIHLRK-RPLDEDVdLEELAEAteglSGADIRNVVRraA 368
|
250
....*....|....*.
gi 499182012 204 LQGAAAIGEVVDADTI 219
Cdd:COG0464 369 LQALRLGREPVTTEDL 384
|
|
| HolA |
COG1466 |
DNA polymerase III, delta subunit [Replication, recombination and repair]; |
89-272 |
5.35e-11 |
|
DNA polymerase III, delta subunit [Replication, recombination and repair];
Pssm-ID: 441075 [Multi-domain] Cd Length: 305 Bit Score: 62.19 E-value: 5.35e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 89 IKEFARTAPIGGAPfKIIFLDEADALTA--DAQAALRRTMEMYSKSCRFILSCNYV---SRIIEPIQSRCAVFRFKPVPK 163
Cdd:COG1466 50 LLDEAQTLSLFGER-RLVIVRNAEFLKKpgEGLEALEAYLANPPPDTVLVLTAGKLdkrKKLFKALEKAGVVVECYPLKE 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 164 EAMKKRLLEICEKEGVKITEDGLEALIYISGGDFRKAINALQ---GAAAIGEVVDADTIYQITATARPEEMTELIQTALK 240
Cdd:COG1466 129 RELPAWIRQRLKAAGLRIDPDAAQLLAERVGGDLLALAQELEklaLYAGDGGTITLEDVEALVGDSAEFNVFDLADALLA 208
|
170 180 190
....*....|....*....|....*....|....*
gi 499182012 241 GNFMEARELLDRLMVEygmsGED---IVAQLFREI 272
Cdd:COG1466 209 GDAARALRILRRLLAE----GEEpvlILAALARQF 239
|
|
| PRK09112 |
PRK09112 |
DNA polymerase III subunit delta'; Validated |
13-273 |
1.41e-10 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 169667 [Multi-domain] Cd Length: 351 Bit Score: 61.59 E-value: 1.41e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 13 PRTLDEVVGQDEVIQRLKGYVERKNIPH-LLFSGPPGTGKTATAIALARDLFGEN------------------WRDnfIE 73
Cdd:PRK09112 19 PSENTRLFGHEEAEAFLAQAYREGKLHHaLLFEGPEGIGKATLAFHLANHILSHPdpaeapetladpdpaspvWRQ--IA 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 74 MNAS----------DERG--------IDVVRHKIKEFARTAPIGGapFKIIFLDEADALTADAQAALRRTMEMYSKSCRF 135
Cdd:PRK09112 97 QGAHpnllhitrpfDEKTgkfktaitVDEIRRVGHFLSQTSGDGN--WRIVIIDPADDMNRNAANAILKTLEEPPARALF 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 136 ILSCNYVSRIIEPIQSRCAVFRFKPVPKEAMKKRLLEIcekeGVKITEDG--LEALIYISGGDFRKAINALQ-GAAAIge 212
Cdd:PRK09112 175 ILISHSSGRLLPTIRSRCQPISLKPLDDDELKKALSHL----GSSQGSDGeiTEALLQRSKGSVRKALLLLNyGGLEI-- 248
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 499182012 213 vvdADTIYQITATARP---------EEMTELIQTALKGNFMeaRELLDRLM---VEYGMSGE----DIVAQLFREII 273
Cdd:PRK09112 249 ---IATIDQLLAGSGPdarkahklaDALSGRESEVQFDFFR--DHLLDRIMaeaRRAAEAGDlalaERLARLWSEII 320
|
|
| COG1223 |
COG1223 |
Predicted ATPase, AAA+ superfamily [General function prediction only]; |
16-117 |
1.62e-10 |
|
Predicted ATPase, AAA+ superfamily [General function prediction only];
Pssm-ID: 440836 [Multi-domain] Cd Length: 246 Bit Score: 60.28 E-value: 1.62e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 16 LDEVVGQDEVIQRLKG---YVERKNIP---------HLLFSGPPGTGKTATAIALARDLfgenwRDNFIEMNASD----- 78
Cdd:COG1223 1 LDDVVGQEEAKKKLKLiikELRRRENLrkfglwpprKILFYGPPGTGKTMLAEALAGEL-----KLPLLTVRLDSligsy 75
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 499182012 79 ----ERGIdvvrHKIKEFARTAPIggapfkIIFLDEADALTAD 117
Cdd:COG1223 76 lgetARNL----RKLFDFARRAPC------VIFFDEFDAIAKD 108
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
4-209 |
1.67e-10 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 61.79 E-value: 1.67e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 4 FEIWVEKYRPRTLDEVVGQDEVIQRLKGYVERKNIPH-LLFSGPPGTGKTATAIALARDLFGEN------------WRD- 69
Cdd:PRK07003 3 YQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHaYLFTGTRGVGKTTLSRIFAKALNCETgvtsqpcgvcraCREi 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 70 ------NFIEMNASDERGIDVVRhKIKEFARTAPIGgAPFKIIFLDEADALTADAQAALRRTMEMYSKSCRFILSCNYVS 143
Cdd:PRK07003 83 degrfvDYVEMDAASNRGVDEMA-ALLERAVYAPVD-ARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQ 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 499182012 144 RIIEPIQSRCAVFRFKPVPKEAMKKRLLEICEKEGVKITEDGLEALIYISGGDFRKAINALQGAAA 209
Cdd:PRK07003 161 KIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEERIAFEPQALRLLARAAQGSMRDALSLTDQAIA 226
|
|
| RuvB_N |
pfam05496 |
Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the ... |
12-62 |
5.55e-10 |
|
Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the RuvABC revolvasome which catalyzes the resolution of Holliday junctions that arise during genetic recombination and DNA repair. Branch migration is catalyzed by the RuvB protein that is targeted to the Holliday junction by the structure specific RuvA protein. This family contains the N-terminal region of the protein.
Pssm-ID: 398900 [Multi-domain] Cd Length: 159 Bit Score: 57.12 E-value: 5.55e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 499182012 12 RPRTLDEVVGQDEVIQRLKGYVE----RKNIP-HLLFSGPPGTGKTATAIALARDL 62
Cdd:pfam05496 2 RPRTLDEYIGQEKVKENLKIFIEaakqRGEALdHVLLYGPPGLGKTTLANIIANEM 57
|
|
| RPT1 |
COG1222 |
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein ... |
4-126 |
8.53e-10 |
|
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440835 [Multi-domain] Cd Length: 326 Bit Score: 58.86 E-value: 8.53e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 4 FEIWVEKYRPRTLDEVVGQDEVIQRLKGYVE--RKNiPHL------------LFSGPPGTGKTATAIALARDLfgenwRD 69
Cdd:COG1222 65 GTAVPAESPDVTFDDIGGLDEQIEEIREAVElpLKN-PELfrkygieppkgvLLYGPPGTGKTLLAKAVAGEL-----GA 138
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 499182012 70 NFIEMNASD---------ERGIdvvrHKIKEFART-APIggapfkIIFLDEADALTADAQ-----AALRRTM 126
Cdd:COG1222 139 PFIRVRGSElvskyigegARNV----REVFELAREkAPS------IIFIDEIDAIAARRTddgtsGEVQRTV 200
|
|
| ruvB |
PRK00080 |
Holliday junction branch migration DNA helicase RuvB; |
12-57 |
1.32e-09 |
|
Holliday junction branch migration DNA helicase RuvB;
Pssm-ID: 234619 [Multi-domain] Cd Length: 328 Bit Score: 58.22 E-value: 1.32e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 499182012 12 RPRTLDEVVGQDEVIQRLKGYVE-----RKNIPHLLFSGPPGTGKT--ATAIA 57
Cdd:PRK00080 20 RPKSLDEFIGQEKVKENLKIFIEaakkrGEALDHVLLYGPPGLGKTtlANIIA 72
|
|
| RuvB |
COG2255 |
Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, ... |
12-57 |
4.84e-09 |
|
Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, recombination and repair];
Pssm-ID: 441856 [Multi-domain] Cd Length: 337 Bit Score: 56.63 E-value: 4.84e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 499182012 12 RPRTLDEVVGQDEVIQRLKGYVE----RKN-IPHLLFSGPPGTGKT--ATAIA 57
Cdd:COG2255 23 RPKRLDEYIGQEKVKENLKIFIEaakkRGEaLDHVLLYGPPGLGKTtlAHIIA 75
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
40-149 |
1.90e-08 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 52.76 E-value: 1.90e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 40 HLLFSGPPGTGKTATAIALARDLFGENWRDNFIEMNASDERGIDVVRHKIKEFARTAPIGGA------------PFKIIF 107
Cdd:smart00382 4 VILIVGPPGSGKTTLARALARELGPPGGGVIYIDGEDILEEVLDQLLLIIVGGKKASGSGELrlrlalalarklKPDVLI 83
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 499182012 108 LDEADALTADAQAALRRTMEMYS--------KSCRFILSCNYVSRIIEPI 149
Cdd:smart00382 84 LDEITSLLDAEQEALLLLLEELRlllllkseKNLTVILTTNDEKDLGPAL 133
|
|
| RecA-like_protease |
cd19481 |
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ... |
41-117 |
2.66e-07 |
|
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410889 [Multi-domain] Cd Length: 158 Bit Score: 49.59 E-value: 2.66e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 41 LLFSGPPGTGKTATAIALARDLfgenwRDNFIEMNASD--ERGIDVVR---HKIKEFARTApiggAPfKIIFLDEADALT 115
Cdd:cd19481 29 ILLYGPPGTGKTLLAKALAGEL-----GLPLIVVKLSSllSKYVGESEknlRKIFERARRL----AP-CILFIDEIDAIG 98
|
..
gi 499182012 116 AD 117
Cdd:cd19481 99 RK 100
|
|
| RecA-like_ClpB_Hsp104-like |
cd19499 |
Chaperone protein ClpB/Hsp104 subfamily; Bacterial Caseinolytic peptidase B (ClpB) and ... |
17-112 |
3.39e-07 |
|
Chaperone protein ClpB/Hsp104 subfamily; Bacterial Caseinolytic peptidase B (ClpB) and eukaryotic Heat shock protein 104 (Hsp104) are ATP-dependent molecular chaperones and essential proteins of the heat-shock response. ClpB/Hsp104 ATPases, in concert with the DnaK/Hsp70 chaperone system, disaggregate and reactivate aggregated proteins. This RecA-like_ClpB_Hsp104_like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410907 [Multi-domain] Cd Length: 178 Bit Score: 49.48 E-value: 3.39e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 17 DEVVGQDE----VIQRLKGYV-----ERKNIPHLLFSGPPGTGKTATAIALARDLFGENwrDNFI--EMNASDErgidvv 85
Cdd:cd19499 11 ERVVGQDEavkaVSDAIRRARaglsdPNRPIGSFLFLGPTGVGKTELAKALAELLFGDE--DNLIriDMSEYME------ 82
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 499182012 86 RHKIKEFARTAPI------GGA--------PFKIIFLDEAD 112
Cdd:cd19499 83 KHSVSRLIGAPPGyvgyteGGQlteavrrkPYSVVLLDEIE 123
|
|
| T7SS_EccA |
TIGR03922 |
type VII secretion AAA-ATPase EccA; This model represents the AAA family ATPase, EccA, of the ... |
14-114 |
3.56e-06 |
|
type VII secretion AAA-ATPase EccA; This model represents the AAA family ATPase, EccA, of the actinobacterial flavor of type VII secretion systems. Species such as Mycobacterium tuberculosis have several instances of this system per genome, designated EccA1, EccA2, etc. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 188437 [Multi-domain] Cd Length: 557 Bit Score: 48.30 E-value: 3.56e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 14 RTLDEVVGQDEV---IQRLKGYVE------RKNIP------HLLFSGPPGTGKTATAIALARDLFGENW--RDNFIEMNA 76
Cdd:TIGR03922 273 AELAEQIGLERVkrqVAALKSSTAmalaraERGLPvaqtsnHMLFAGPPGTGKTTIARVVAKIYCGLGVlrKPLVREVSR 352
|
90 100 110
....*....|....*....|....*....|....*....
gi 499182012 77 SDERGidvvRHKIKEFART-APIGGAPFKIIFLDEADAL 114
Cdd:TIGR03922 353 ADLIG----QYIGESEAKTnEIIDSALGGVLFLDEAYTL 387
|
|
| COG2842 |
COG2842 |
Bacteriophage DNA transposition protein, AAA+ family ATPase [Mobilome: prophages, transposons]; ... |
42-219 |
4.93e-06 |
|
Bacteriophage DNA transposition protein, AAA+ family ATPase [Mobilome: prophages, transposons];
Pssm-ID: 442090 [Multi-domain] Cd Length: 254 Bit Score: 46.87 E-value: 4.93e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 42 LFSGPPGTGKTATAIALArdlfgeNWRDN--FIEMNAS-----------DERGIDVVRHKIKEFARTA--PIGGAPFKII 106
Cdd:COG2842 54 VVYGESGVGKTTAAREYA------NRNPNviYVTASPSwtskelleelaEELGIPAPPGTIADLRDRIleRLAGTGRLLI 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 107 fLDEADALTADAQAALRRtmeMYSKS-CRFILSCN--YVSRI--IEPIQSRCA-VFRFKPVPKEAMKKrLLEICEkegvK 180
Cdd:COG2842 128 -IDEADHLKPKALEELRD---IHDETgVGVVLIGMerLPAKLkrYEQLYSRIGfWVEFKPLSLEDVRA-LAEAWG----E 198
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 499182012 181 ITEDGL-EALIYISGGDFRKAINALQGAAAI-----GEVVDADTI 219
Cdd:COG2842 199 LTDPDLlELLHRITRGNLRRLDRTLRLAARAakrngLTKITLDHV 243
|
|
| AAA_assoc_2 |
pfam16193 |
AAA C-terminal domain; AAA_assoc_2 is found at the C-terminus of a relatively small set of AAA ... |
175-236 |
8.54e-06 |
|
AAA C-terminal domain; AAA_assoc_2 is found at the C-terminus of a relatively small set of AAA domains in proteins ranging from archaeal to fungi, plants and mammals.
Pssm-ID: 465057 Cd Length: 81 Bit Score: 43.23 E-value: 8.54e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 499182012 175 EKEGVKITEDGLEALIYISGGDFRKAINALQGAAAIGEVVDADTIyqITatarPEEMTELIQ 236
Cdd:pfam16193 1 GGLKIELDDEALEALAELADGDARRALNALELAVLSTPPDDGGIH--IT----LEILEEALQ 56
|
|
| Rad17 |
pfam03215 |
Rad17 P-loop domain; |
4-62 |
1.30e-05 |
|
Rad17 P-loop domain;
Pssm-ID: 367398 [Multi-domain] Cd Length: 186 Bit Score: 44.95 E-value: 1.30e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 499182012 4 FEIWVEKYRPRTLDEVVGQDEVIQRLKGY-----VERKNIPHLLFSGPPGTGKTATAIALARDL 62
Cdd:pfam03215 6 GEQWYEKYKPNCLEQLAVHKRKIKDVQEWldamfLENAKHRILLISGPSGCGKSTVIKELSKEL 69
|
|
| RecA-like_FtsH |
cd19501 |
ATP-dependent zinc metalloprotease FtsH; FtsH ATPase is a processive, ATP-dependent zinc ... |
15-114 |
1.47e-05 |
|
ATP-dependent zinc metalloprotease FtsH; FtsH ATPase is a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. It is anchored to the cytoplasmic membrane such that the amino- and carboxy-termini are exposed to the cytoplasm. It presents a membrane-bound hexameric structure that is able to unfold and degrade protein substrates. It is comprised of an N-terminal transmembrane region and the larger C-terminal cytoplasmic region, which consists of an ATPase domain and a protease domain. This RecA-Like FTsH subfamily represents the ATPase domain, and belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410909 [Multi-domain] Cd Length: 171 Bit Score: 44.53 E-value: 1.47e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 15 TLDEVVGQDEVIQRLKGYVE-RKN----------IPH-LLFSGPPGTGKTATAIALArdlfGENwRDNFIEMNASD--ER 80
Cdd:cd19501 2 TFKDVAGCEEAKEELKEVVEfLKNpekftklgakIPKgVLLVGPPGTGKTLLAKAVA----GEA-GVPFFSISGSDfvEM 76
|
90 100 110
....*....|....*....|....*....|....*...
gi 499182012 81 GIDV----VRHKIKEFARTAPIggapfkIIFLDEADAL 114
Cdd:cd19501 77 FVGVgasrVRDLFEQAKKNAPC------IVFIDEIDAV 108
|
|
| holA |
TIGR01128 |
DNA polymerase III, delta subunit; DNA polymerase III delta (holA) and delta prime (holB) ... |
71-318 |
1.72e-05 |
|
DNA polymerase III, delta subunit; DNA polymerase III delta (holA) and delta prime (holB) subunits are distinct proteins encoded by separate genes. The delta prime subunit (holB) exhibits sequence homology to the tau and gamma subunits (dnaX), but the delta subunit (holA) does not demonstrate this same homology with dnaX. The delta, delta prime, gamma, chi and psi subunits form the gamma complex subassembly of DNA polymerase III holoenzyme, which couples ATP to assemble the ring-shaped beta subunit around DNA forming a DNA sliding clamp. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273455 [Multi-domain] Cd Length: 302 Bit Score: 45.71 E-value: 1.72e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 71 FIEMNASDERGIDVVRHKIKEFARTAPIGgAPFKIIFLDEADALT-ADAQAALRRTMEMYSKSCRFILSCNYVSRIIEPI 149
Cdd:TIGR01128 16 FDEFNVFRIDGEEFDWNQLLEEAQTLPLF-SERRLVELRNPEGKPgAKGLKALEEYLANPPPDTLLLIEAPKLDKRKKLT 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 150 Q-----SRCAVFRFKPVPKEAMKKRLLEICEKEGVKITEDGLEALIYISGGDFRKAINALQGAAAI--GEVVDADTIYQI 222
Cdd:TIGR01128 95 KwlkalKNAEIVECKTPKEQELPRWIQARLKKLGLRIDPDAVQLLAELVEGNLLAIAQELEKLALYapDGKITLEDVEEA 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 223 TATARPEEMTELIQTALKGNFMEARELLDRLMVEygmsGED------IVAQLFREIISMPI---KDSLKVQLIDKLGEVD 293
Cdd:TIGR01128 175 VSDSARFNVFDLTDALLEGKAARALRILKGLLGE----GEEplillaLLQRQLRLLLQLKRlaqQGGPLAQLASKLGIWP 250
|
250 260
....*....|....*....|....*..
gi 499182012 294 FR--LTEGANERIQLDAYLAYLSTLAK 318
Cdd:TIGR01128 251 YRrkLALKALRRLSLAKLEQALQELAE 277
|
|
| TIP49 |
COG1224 |
DNA helicase TIP49, TBP-interacting protein [Transcription]; |
17-78 |
2.14e-05 |
|
DNA helicase TIP49, TBP-interacting protein [Transcription];
Pssm-ID: 440837 [Multi-domain] Cd Length: 452 Bit Score: 45.73 E-value: 2.14e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 17 DEVVGQDE-------VIQRLK-GYVERKNIphlLFSGPPGTGKTATAIALARDLfGENwrDNFIEMNASD 78
Cdd:COG1224 38 DGLVGQVEareaagiVVKMIKeGKMAGKGI---LIVGPPGTGKTALAVAIAREL-GED--TPFVAISGSE 101
|
|
| AAA_22 |
pfam13401 |
AAA domain; |
40-138 |
2.29e-05 |
|
AAA domain;
Pssm-ID: 379165 [Multi-domain] Cd Length: 129 Bit Score: 43.10 E-value: 2.29e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 40 HLLFSGPPGTGKTATAIALARDLfgENWRDNFIEMNASDERGIDVVRHKIKEFARTAPIGGAPFK--------------- 104
Cdd:pfam13401 7 ILVLTGESGTGKTTLLRRLLEQL--PEVRDSVVFVDLPSGTSPKDLLRALLRALGLPLSGRLSKEellaalqqlllalav 84
|
90 100 110
....*....|....*....|....*....|....*.
gi 499182012 105 --IIFLDEADALTADAQAALRRTMEMYSKSCRFILS 138
Cdd:pfam13401 85 avVLIIDEAQHLSLEALEELRDLLNLSSKLLQLILV 120
|
|
| PRK06090 |
PRK06090 |
DNA polymerase III subunit delta'; Validated |
103-153 |
2.78e-05 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 180394 [Multi-domain] Cd Length: 319 Bit Score: 45.18 E-value: 2.78e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 499182012 103 FKIIFLDEADALTADAQAALRRTMEMYSKSCRFILSCNYVSRIIEPIQSRC 153
Cdd:PRK06090 109 YRLFVIEPADAMNESASNALLKTLEEPAPNCLFLLVTHNQKRLLPTIVSRC 159
|
|
| HLD_clamp_RarA |
cd18139 |
helical lid domain of recombination factor protein RarA; Recombination factor RarA ... |
163-219 |
2.80e-05 |
|
helical lid domain of recombination factor protein RarA; Recombination factor RarA (Replication associated recombination gene/protein A, also known as MgsA (Maintenance of genome stability A) or Mgs1 in yeast and WRNIP1 in mammals) is a member of the clamp-loader clade of the AAA+ superfamily. It functions as a tetramer. RarA co-localize with the replication fork throughout the cell cycle and may play a role in the rescue of stalled replication forks.
Pssm-ID: 350841 [Multi-domain] Cd Length: 75 Bit Score: 41.46 E-value: 2.80e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 499182012 163 KEAMKKRL--LEICEKEGVKITEDGLEALIYISGGDFRKAINALQGAAAI-----GEVVDADTI 219
Cdd:cd18139 7 EKLLKRALedKERGGDRKVTIDDEALELLAEAADGDARSALNLLELAVLSaeedgGIVITLEDL 70
|
|
| ruvB |
TIGR00635 |
Holliday junction DNA helicase, RuvB subunit; All proteins in this family for which functions ... |
14-62 |
3.79e-05 |
|
Holliday junction DNA helicase, RuvB subunit; All proteins in this family for which functions are known are 5'-3' DNA helicases that, as part of a complex with RuvA homologs serve as a 5'-3' Holliday junction helicase. RuvA specifically binds Holliday junctions as a sandwich of two tetramers and maintains the configuration of the junction. It forms a complex with two hexameric rings of RuvB, the subunit that contains helicase activity. The complex drives ATP-dependent branch migration of the Holliday junction recombination intermediate. The endonuclease RuvC resolves junctions. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129721 [Multi-domain] Cd Length: 305 Bit Score: 44.60 E-value: 3.79e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 499182012 14 RTLDEVVGQDEVIQRL----KGYVERKNIP-HLLFSGPPGTGKTATAIALARDL 62
Cdd:TIGR00635 1 KLLAEFIGQEKVKEQLqlfiEAAKMRQEALdHLLLYGPPGLGKTTLAHIIANEM 54
|
|
| HLD_clamp_pol_III_gamma_tau |
cd18137 |
helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit ... |
161-223 |
4.02e-05 |
|
helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit gamma/tau is part of the DNA polymerase III holoenzyme. Gamma and tau subunits are isoforms, both containing the helical lid domain. Gamma interacts with the delta subunit to transfer the beta subunit on the DNA while tau serves as a scaffold to help in the dimerization of the core complex. Both are members of the clamp-loader clade of the AAA+ superfamily.
Pssm-ID: 350839 [Multi-domain] Cd Length: 65 Bit Score: 40.95 E-value: 4.02e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 499182012 161 VPKEAMKKRLLEICEKEGVKITEDGLEALIYISGGDFRKAINAL-QGAAAIGEVVDADTIYQIT 223
Cdd:cd18137 1 ISVEDIVGRLAHILEKEGIEIEDEALELIARAAEGSMRDALSLLdQAIAFGGGRVTLDDVREML 64
|
|
| PRK08699 |
PRK08699 |
DNA polymerase III subunit delta'; Validated |
41-165 |
5.34e-05 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 181538 [Multi-domain] Cd Length: 325 Bit Score: 44.09 E-value: 5.34e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 41 LLFSGPPGTGKTATAIALARDL--------------------FGENWRDNFIEMNA-SDER---------GIDVVRHKIK 90
Cdd:PRK08699 24 WLFAGKKGIGKTAFARFAAQALlcetpapghkpcgecmschlFGQGSHPDFYEITPlSDEPengrkllqiKIDAVREIID 103
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 499182012 91 EFARTAPIGGapFKIIFLDEADALTADAQAALRRTMEMYSKSCRFILSCNYVSRIIEPIQSRCAVFRFKPVPKEA 165
Cdd:PRK08699 104 NVYLTSVRGG--LRVILIHPAESMNLQAANSLLKVLEEPPPQVVFLLVSHAADKVLPTIKSRCRKMVLPAPSHEE 176
|
|
| PRK06871 |
PRK06871 |
DNA polymerase III subunit delta'; Validated |
81-165 |
2.02e-04 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 180738 [Multi-domain] Cd Length: 325 Bit Score: 42.41 E-value: 2.02e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 81 GIDVVRH---KIKEFARTapiGGApfKIIFLDEADALTADAQAALRRTMEMYSKSCRFILSCNYVSRIIEPIQSRCAVFR 157
Cdd:PRK06871 88 GVDQVREineKVSQHAQQ---GGN--KVVYIQGAERLTEAAANALLKTLEEPRPNTYFLLQADLSAALLPTIYSRCQTWL 162
|
....*...
gi 499182012 158 FKPvPKEA 165
Cdd:PRK06871 163 IHP-PEEQ 169
|
|
| MoxR |
COG0714 |
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway ... |
19-127 |
2.07e-04 |
|
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 440478 [Multi-domain] Cd Length: 292 Bit Score: 42.46 E-value: 2.07e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 19 VVGQDEVIQRL------KGyverknipHLLFSGPPGTGKTATAIALARDLFGENWRDNF-IEMNASDERGIDV-VRHKIK 90
Cdd:COG0714 14 YVGQEELIELVliallaGG--------HLLLEGVPGVGKTTLAKALARALGLPFIRIQFtPDLLPSDILGTYIyDQQTGE 85
|
90 100 110
....*....|....*....|....*....|....*..
gi 499182012 91 EFARTAPIGGApfkIIFLDEADALTADAQAALRRTME 127
Cdd:COG0714 86 FEFRPGPLFAN---VLLADEINRAPPKTQSALLEAME 119
|
|
| RecA-like_CDC48_NLV2_r1-like |
cd19503 |
first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and ... |
18-115 |
2.24e-04 |
|
first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and p97 or VCP metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the first of the two ATPase domains. This subfamily also includes the first of the two ATPase domains of NVL (nuclear VCP-like protein) 2, an isoform of NVL mainly present in the nucleolus, which is involved in ribosome biogenesis, in telomerase assembly and the regulation of telomerase activity, and in pre-rRNA processing. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410911 [Multi-domain] Cd Length: 165 Bit Score: 41.12 E-value: 2.24e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 18 EVVGQDEVIQRLKGYVE---RKN----------IPHLLFSGPPGTGKTATAIALARDLfgenwRDNFIEMNA-------- 76
Cdd:cd19503 1 DIGGLDEQIASLKELIElplKYPelfralglkpPRGVLLHGPPGTGKTLLARAVANEA-----GANFLSISGpsivskyl 75
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 499182012 77 --SDERgidvVRHKIKEFARTAPiggapfKIIFLDEADALT 115
Cdd:cd19503 76 geSEKN----LREIFEEARSHAP------SIIFIDEIDALA 106
|
|
| AAA_16 |
pfam13191 |
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the ... |
18-120 |
2.32e-04 |
|
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.
Pssm-ID: 433025 [Multi-domain] Cd Length: 167 Bit Score: 40.95 E-value: 2.32e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 18 EVVGQDEVIQRLKGYVERKNI---PHLLFSGPPGTGKTATAIALARDLFGENWRdnFIEMNASDERGIDVVRHKIKEFAR 94
Cdd:pfam13191 1 RLVGREEELEQLLDALDRVRSgrpPSVLLTGEAGTGKTTLLRELLRALERDGGY--FLRGKCDENLPYSPLLEALTREGL 78
|
90 100
....*....|....*....|....*.
gi 499182012 95 TAPIGGAPFKIIFLDEADALTADAQA 120
Cdd:pfam13191 79 LRQLLDELESSLLEAWRAALLEALAP 104
|
|
| AAA_2 |
pfam07724 |
AAA domain (Cdc48 subfamily); This Pfam entry includes some of the AAA proteins not detected ... |
42-122 |
2.60e-04 |
|
AAA domain (Cdc48 subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400187 [Multi-domain] Cd Length: 168 Bit Score: 41.03 E-value: 2.60e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 42 LFSGPPGTGKTATAIALARDLFGEnwRDNFIEMNAS---------------------DERGI--DVVRHKikefartapi 98
Cdd:pfam07724 7 LFLGPTGVGKTELAKALAELLFGD--ERALIRIDMSeymeehsvsrligappgyvgyEEGGQltEAVRRK---------- 74
|
90 100
....*....|....*....|....
gi 499182012 99 ggaPFKIIFLDEADALTADAQAAL 122
Cdd:pfam07724 75 ---PYSIVLIDEIEKAHPGVQNDL 95
|
|
| DEXHc_RE |
cd17926 |
DEXH-box helicase domain of DEAD-like helicase restriction enzyme family proteins; This family ... |
22-138 |
2.87e-04 |
|
DEXH-box helicase domain of DEAD-like helicase restriction enzyme family proteins; This family is composed of helicase restriction enzymes and similar proteins such as TFIIH basal transcription factor complex helicase XPB subunit. These proteins are part of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350684 [Multi-domain] Cd Length: 146 Bit Score: 40.37 E-value: 2.87e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 22 QDEVIQRLKGYverKNIPHLLFSGPPGTGKTATAIALARDLFGEN-------------WRDNFIEMNASDERGIdvVRHK 88
Cdd:cd17926 5 QEEALEAWLAH---KNNRRGILVLPTGSGKTLTALALIAYLKELRtlivvptdalldqWKERFEDFLGDSSIGL--IGGG 79
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 499182012 89 IKEFARTAPI-----------------GGAPFKIIFLDEADALTADaqaALRRTMEMYSKSCRFILS 138
Cdd:cd17926 80 KKKDFDDANVvvatyqslsnlaeeekdLFDQFGLLIVDEAHHLPAK---TFSEILKELNAKYRLGLT 143
|
|
| RecA-like_PAN_like |
cd19502 |
proteasome activating nucleotidase PAN and related proteasome subunits; This subfamily ... |
15-116 |
4.42e-04 |
|
proteasome activating nucleotidase PAN and related proteasome subunits; This subfamily contains ATPase subunits of the eukaryotic 26S proteasome, and of the archaeal proteasome which carry out ATP-dependent degradation of substrates of the ubiquitin-proteasome pathway. The eukaryotic 26S proteasome consists of a proteolytic 20S core particle (CP), and a 19S regulatory particle (RP) which provides the ATP-dependence and the specificity for ubiquitinated proteins. In the archaea the RP is a homohexameric complex of proteasome-activating nucleotidase (PAN). This subfamily also includes various eukaryotic 26S subunits including, proteasome 26S subunit, ATPase 2 (PSMC2, also known as S7 and MSS1) which is a member of the 19S RP and has a chaperone like activity; and proteasome 20S subunit alpha 6 (PSMA6, also known as IOTA, p27K, and PROS27) which is a member of the 20S CP. This RecA-like_PAN subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410910 [Multi-domain] Cd Length: 171 Bit Score: 40.40 E-value: 4.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 15 TLDEVVGQDEVIQRLKGYVER--KNiPHL------------LFSGPPGTGKTATAIALARDLfgenwRDNFIEMNASD-- 78
Cdd:cd19502 1 TYEDIGGLDEQIREIREVVELplKH-PELfeelgieppkgvLLYGPPGTGKTLLAKAVANHT-----DATFIRVVGSElv 74
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 499182012 79 ----ERGIDVVRhKIKEFART-APiggapfKIIFLDEADALTA 116
Cdd:cd19502 75 qkyiGEGARLVR-ELFEMAREkAP------SIIFIDEIDAIGA 110
|
|
| RecA-like_CDC48_r2-like |
cd19511 |
second of two ATPase domains of CDC48/p97, PEX1 and -6, VAT and NVL, and similar ATPase ... |
42-117 |
7.42e-04 |
|
second of two ATPase domains of CDC48/p97, PEX1 and -6, VAT and NVL, and similar ATPase domains; This subfamily includes the second of two ATPase domains of the molecular chaperone CDC48 in yeast and p97 or VCP in metazoans, Peroxisomal biogenesis factor 1 (PEX1) and -6 (PEX6), Valosin-containing protein-like ATPase (VAT), and nuclear VCP-like protein (NVL). This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410919 [Multi-domain] Cd Length: 159 Bit Score: 39.57 E-value: 7.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 42 LFSGPPGTGKTATAIALArdlfgENWRDNFIEMNASD---------ERGIDVVRHKikefARTApiggAPfKIIFLDEAD 112
Cdd:cd19511 31 LLYGPPGCGKTLLAKALA-----SEAGLNFISVKGPElfskyvgesERAVREIFQK----ARQA----AP-CIIFFDEID 96
|
....*
gi 499182012 113 ALTAD 117
Cdd:cd19511 97 SLAPR 101
|
|
| CDC6 |
COG1474 |
Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair]; |
11-89 |
8.07e-04 |
|
Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair];
Pssm-ID: 441083 [Multi-domain] Cd Length: 389 Bit Score: 40.60 E-value: 8.07e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 11 YRPrtlDEVVGQDEVIQRLKGYVE---RKNIP-HLLFSGPPGTGKTATAIALARDLfgenwrdnfieMNASDERGIDVVR 86
Cdd:COG1474 23 YVP---DRLPHREEEIEELASALRpalRGERPsNVLIYGPTGTGKTAVAKYVLEEL-----------EEEAEERGVDVRV 88
|
...
gi 499182012 87 HKI 89
Cdd:COG1474 89 VYV 91
|
|
| RecA-like_NVL_r1-like |
cd19518 |
first of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL ... |
41-127 |
9.80e-04 |
|
first of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL exists in two forms with N-terminal extensions of different lengths in mammalian cells. NVL has two alternatively spliced isoforms, a short form, NVL1, and a long form, NVL2. NVL2, the major species, is mainly present in the nucleolus, whereas NVL1 is nucleoplasmic. Each has an N-terminal domain, followed by two tandem ATPase domains; this subfamily includes the first of the two ATPase domains. NVL2 is involved in the biogenesis of the 60S ribosome subunit by associating specifically with ribosome protein L5 and modulating the function of DOB1. NVL2 is also required for telomerase assembly and the regulation of telomerase activity, and is involved in pre-rRNA processing. The role of NVL1 is unclear. This RecA-like_NVL_r1-like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410926 [Multi-domain] Cd Length: 169 Bit Score: 39.31 E-value: 9.80e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 41 LLFSGPPGTGKTATAIALARDLfgenwRDNFIEMNA----------SDERgidvVRHKIKEFARTAPIggapfkIIFLDE 110
Cdd:cd19518 37 VLLHGPPGCGKTMLANAIAGEL-----KVPFLKISAteivsgvsgeSEEK----IRELFDQAISNAPC------IVFIDE 101
|
90
....*....|....*..
gi 499182012 111 ADALTADAQAAlRRTME 127
Cdd:cd19518 102 IDAITPKRESA-QREME 117
|
|
| AAA_7 |
pfam12775 |
P-loop containing dynein motor region; This domain is found in human cytoplasmic dynein-2 ... |
40-76 |
1.49e-03 |
|
P-loop containing dynein motor region; This domain is found in human cytoplasmic dynein-2 proteins. Cytoplasmic dynein-2 (dynein-2) performs intraflagellar transport and is associated with human skeletal ciliopathies. Dyneins share a conserved motor domain that couples cycles of ATP hydrolysis with conformational changes to produce movement. Structural analysis reveal that the motor's ring consists of six AAA+ domains (ATPases associated with various cellular activities (AAA1-AAA6). This is the third nucleotide binding sites in the dynein motor. However, AAA3 has lost the catalytic residues necessary for ATP hydrolysis (the Walker B glutamate, the arginine finger, sensor-I and sensor-II motifs).
Pssm-ID: 463698 [Multi-domain] Cd Length: 179 Bit Score: 38.91 E-value: 1.49e-03
10 20 30
....*....|....*....|....*....|....*..
gi 499182012 40 HLLFSGPPGTGKTATAIALARDLFGENWRDNFIEMNA 76
Cdd:pfam12775 33 PVLLVGPTGTGKTVIIQNLLRKLDKEKYLPLFINFSA 69
|
|
| ClpA |
COG0542 |
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
19-64 |
1.64e-03 |
|
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 40.06 E-value: 1.64e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 499182012 19 VVGQDEVIQRLKGYVER-----KNiPH-----LLFSGPPGTGKTATAIALARDLFG 64
Cdd:COG0542 551 VIGQDEAVEAVADAIRRsraglKD-PNrpigsFLFLGPTGVGKTELAKALAEFLFG 605
|
|
| RecA-like_ATAD3-like |
cd19512 |
ATPase domains of ATPase AAA-domain protein 3A (ATAD3A), -3B, and -3C, and similar ATPase ... |
40-113 |
2.05e-03 |
|
ATPase domains of ATPase AAA-domain protein 3A (ATAD3A), -3B, and -3C, and similar ATPase domains; ATPase AAA-domain protein 3 (ATAD3) is a ubiquitously expressed mitochondrial protein involved in mitochondrial dynamics, DNA-nucleoid structural organization, cholesterol transport and steroidogenesis. The ATAD3 gene family in human comprises three paralog genes: ATAD3A, ATAD3B and ATAD3C. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410920 [Multi-domain] Cd Length: 150 Bit Score: 37.89 E-value: 2.05e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 499182012 40 HLLFSGPPGTGKTATAIALARdlfgENWRDNFIeMNASD-----ERGIDVVrHKIKEFARTAPIGgapfKIIFLDEADA 113
Cdd:cd19512 24 NILFYGPPGTGKTLFAKKLAL----HSGMDYAI-MTGGDvapmgREGVTAI-HKVFDWANTSRRG----LLLFVDEADA 92
|
|
| hflB |
PRK10733 |
ATP-dependent zinc metalloprotease FtsH; |
27-122 |
2.08e-03 |
|
ATP-dependent zinc metalloprotease FtsH;
Pssm-ID: 182683 [Multi-domain] Cd Length: 644 Bit Score: 39.63 E-value: 2.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 27 QRLKGYVERKniphLLFSGPPGTGKTATAIALARD-------LFGENWRDNFIEMNASDergidvVRHKIKEFARTAPIg 99
Cdd:PRK10733 178 QKLGGKIPKG----VLMVGPPGTGKTLLAKAIAGEakvpfftISGSDFVEMFVGVGASR------VRDMFEQAKKAAPC- 246
|
90 100
....*....|....*....|...
gi 499182012 100 gapfkIIFLDEADALTADAQAAL 122
Cdd:PRK10733 247 -----IIFIDEIDAVGRQRGAGL 264
|
|
| TIP49 |
pfam06068 |
TIP49 P-loop domain; This family consists of the C-terminal region of several eukaryotic and ... |
41-62 |
2.10e-03 |
|
TIP49 P-loop domain; This family consists of the C-terminal region of several eukaryotic and archaeal RuvB-like 1 (Pontin or TIP49a) and RuvB-like 2 (Reptin or TIP49b) proteins. The N-terminal domain contains the pfam00004 domain. In zebrafish, the liebeskummer (lik) mutation, causes development of hyperplastic embryonic hearts. lik encodes Reptin, a component of a DNA-stimulated ATPase complex. Beta-catenin and Pontin, a DNA-stimulated ATPase that is often part of complexes with Reptin, are in the same genetic pathways. The Reptin/Pontin ratio serves to regulate heart growth during development, at least in part via the beta-catenin pathway. TBP-interacting protein 49 (TIP49) was originally identified as a TBP-binding protein, and two related proteins are encoded by individual genes, tip49a and b. Although the function of this gene family has not been elucidated, they are supposed to play a critical role in nuclear events because they interact with various kinds of nuclear factors and have DNA helicase activities.TIP49a has been suggested to act as an autoantigen in some patients with autoimmune diseases.
Pssm-ID: 399217 [Multi-domain] Cd Length: 347 Bit Score: 39.21 E-value: 2.10e-03
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
40-122 |
2.29e-03 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 37.66 E-value: 2.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 40 HLLFSGPPGTGKTATAIALARDLFGENW------RDnfieMNASDERGIDVVRHKIKEF----ARTAPIGGApfkIIFLD 109
Cdd:pfam07728 1 GVLLVGPPGTGKTELAERLAAALSNRPVfyvqltRD----TTEEDLFGRRNIDPGGASWvdgpLVRAAREGE---IAVLD 73
|
90
....*....|...
gi 499182012 110 EADALTADAQAAL 122
Cdd:pfam07728 74 EINRANPDVLNSL 86
|
|
| DEXXQc_Mov10L1 |
cd18078 |
DEXXQ-box helicase domain of Mov10L1; Moloney leukemia virus 10-like protein 1 (Mov10L1) binds ... |
25-56 |
4.80e-03 |
|
DEXXQ-box helicase domain of Mov10L1; Moloney leukemia virus 10-like protein 1 (Mov10L1) binds Piwi-interacting RNA (piRNA) precursors to initiate piRNA processing. Mov10L1 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350836 [Multi-domain] Cd Length: 230 Bit Score: 37.73 E-value: 4.80e-03
10 20 30
....*....|....*....|....*....|..
gi 499182012 25 VIQRLKGyvERKNIPHLLFsGPPGTGKTATAI 56
Cdd:cd18078 10 VKRILGG--ECRPLPYILF-GPPGTGKTVTII 38
|
|
| SSL2 |
COG1061 |
Superfamily II DNA or RNA helicase [Transcription, Replication, recombination, and repair]; |
22-63 |
6.07e-03 |
|
Superfamily II DNA or RNA helicase [Transcription, Replication, recombination, and repair];
Pssm-ID: 440681 [Multi-domain] Cd Length: 566 Bit Score: 38.08 E-value: 6.07e-03
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 499182012 22 QDEVIQRLKGYVERKNiPHLLFSGPPGTGKTATAIALARDLF 63
Cdd:COG1061 85 QQEALEALLAALERGG-GRGLVVAPTGTGKTVLALALAAELL 125
|
|
| DNA_pol3_delta |
pfam06144 |
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ... |
107-205 |
6.58e-03 |
|
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.
Pssm-ID: 428788 [Multi-domain] Cd Length: 174 Bit Score: 36.88 E-value: 6.58e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 107 FLDEADALTADAQAALRRTMEMYSKSCRFILSCNY----VSRIIEPIQSRCAVFRFKPVPKEAMKKRLLEICEKEGVKIT 182
Cdd:pfam06144 68 LLEKESKLNEHLLKRLEEYLSNPPPDSLLILFAPGkldeRKKLTKLLKKKATVVECFTLKEEELIQWIQSRAQELGLQIE 147
|
90 100
....*....|....*....|...
gi 499182012 183 EDGLEALIYISGGDFRKAINALQ 205
Cdd:pfam06144 148 PEAIELLCELVENNLSALAQELE 170
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
10-62 |
7.43e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 37.92 E-value: 7.43e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 499182012 10 KYRPRTLDEVVGQDEVI---------QRLkgyverknipH--LLFSGPPGTGKTATAIALARDL 62
Cdd:PRK07994 9 KWRPQTFAEVVGQEHVLtalanaldlGRL----------HhaYLFSGTRGVGKTTIARLLAKGL 62
|
|
| clpC |
CHL00095 |
Clp protease ATP binding subunit |
19-64 |
8.01e-03 |
|
Clp protease ATP binding subunit
Pssm-ID: 214361 [Multi-domain] Cd Length: 821 Bit Score: 38.11 E-value: 8.01e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 499182012 19 VVGQDEVIQRLKGYVER-----KN----IPHLLFSGPPGTGKTATAIALARDLFG 64
Cdd:CHL00095 511 IIGQDEAVVAVSKAIRRarvglKNpnrpIASFLFSGPTGVGKTELTKALASYFFG 565
|
|
| AAA_24 |
pfam13479 |
AAA domain; This AAA domain is found in a wide variety of presumed phage proteins. |
45-124 |
8.43e-03 |
|
AAA domain; This AAA domain is found in a wide variety of presumed phage proteins.
Pssm-ID: 433243 Cd Length: 199 Bit Score: 36.92 E-value: 8.43e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499182012 45 GPPGTGKTATAIALARDLF-----G----ENWRDNFIEmnasDERGIDVVRHKIKEFARTAPiggAPFKIIFLDEADALT 115
Cdd:pfam13479 9 GPSGIGKTTFAKTLPKPLFldtekGskalDGDRFPDIV----IRDSWQDFLDAIDELTAAEL---ADYKTIVIDTVDWLE 81
|
....*....
gi 499182012 116 ADAQAALRR 124
Cdd:pfam13479 82 RLCLAYICK 90
|
|
| DnaC |
COG1484 |
DNA replication protein DnaC [Replication, recombination and repair]; |
26-62 |
9.44e-03 |
|
DNA replication protein DnaC [Replication, recombination and repair];
Pssm-ID: 441093 [Multi-domain] Cd Length: 242 Bit Score: 37.07 E-value: 9.44e-03
10 20 30
....*....|....*....|....*....|....*....
gi 499182012 26 IQRLKG--YVERKNipHLLFSGPPGTGKTATAIALARDL 62
Cdd:COG1484 87 ILELATldFIERGE--NLILLGPPGTGKTHLAIALGHEA 123
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