|
Name |
Accession |
Description |
Interval |
E-value |
| rRNA_methyl_3 |
TIGR00186 |
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases ... |
7-242 |
5.57e-115 |
|
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129290 [Multi-domain] Cd Length: 237 Bit Score: 328.53 E-value: 5.57e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499177124 7 TSFLFGSKAFLEALDNQ--LQIKKVNLSDKHQKLLGLIKKRGLRYEMHSSQWFHQQFRHINHQEFVCVINPnQMLKTIEQ 84
Cdd:TIGR00186 1 QEYLYGKNAVLEALLNQqrVFILKGLESKRLKKLIQLAKKQGINIQLVDRQKLDQLTKGGNHQGIAAKVKP-ILYKDLND 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499177124 85 LIQITDSKSTSTLVMLHEIQDPHNFGAILRTCMAAEVDGIIFKKHNQAPINSTVIRTSMGTVFYQNLVQVTNLSYAITTL 164
Cdd:TIGR00186 80 LYKTAKSKKQPFLLILDEITDPHNLGAILRTAEAFGVDGVILPKRRSAPLNSTVVKTSSGAVEYVPLARVTNLSRTITKL 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 499177124 165 QKHGFWTVATTLDERLkpKDYRQVDFDKRILLVGNEDKGLNALLLKNADLKVKIPMNPKLNSLNVSVAVGIILFGWKS 242
Cdd:TIGR00186 160 KESGFWTVGTDLDAQD--TLYQVKLTKPLALVVGNEGEGVSRLIKENCDFLIKIPMAGKVDSLNVSVAAGILLFEIKR 235
|
|
| SpoU |
COG0566 |
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA ... |
3-238 |
2.26e-77 |
|
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA G18 (ribose-2'-O)-methylase SpoU is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440332 [Multi-domain] Cd Length: 265 Bit Score: 234.32 E-value: 2.26e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499177124 3 RMQETSFL-FGSKAFLEALDNQLQIKKV----NLSDKHQKLLGLIKKRGLRYEMHSSQWFHQQFRHINHQEFVCVINPNQ 77
Cdd:COG0566 21 REEEGLFLaEGRHAVEEALKAGREIEELlvteGALDRLAELLALAKAAGIPVYEVSREVLDKLSGTETHQGVLAVVRPPE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499177124 78 MLkTIEQLIQitDSKSTSTLVMLHEIQDPHNFGAILRTCMAAEVDGIIFKKHNQAPINSTVIRTSMGTVFYQNLVQVTNL 157
Cdd:COG0566 101 YA-DLEDLLA--EAGEPPLLLVLDGVQDPGNLGAILRSAAAFGVDGVILPKRRADPYNPKVVRASAGALFHVPVARVTNL 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499177124 158 SYAITTLQKHGFWTVATTLDERlkpKDYRQVDFDKRILLV-GNEDKGLNALLLKNADLKVKIPMNPKLNSLNVSVAVGII 236
Cdd:COG0566 178 ADALEELKEAGFWVVGTDLDGE---ASLYEVDLPGPVALVlGNEGKGLSRLVLEACDELVRIPMAGGVESLNVAVAAAIL 254
|
..
gi 499177124 237 LF 238
Cdd:COG0566 255 LY 256
|
|
| SpoU-like_RlmB |
cd18103 |
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the ... |
97-238 |
3.28e-68 |
|
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the methylation of guanosine 2251, a modification conserved in the peptidyltransferase domain of 23S rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349976 Cd Length: 143 Bit Score: 206.47 E-value: 3.28e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499177124 97 LVMLHEIQDPHNFGAILRTCMAAEVDGIIFKKHNQAPINSTVIRTSMGTVFYQNLVQVTNLSYAITTLQKHGFWTVATTL 176
Cdd:cd18103 2 LLILDGITDPHNLGAIIRSAEAFGVDGVIIPKRRSAPLTPTVAKASAGALEHLPIARVTNLARALEELKEAGFWIYGADG 81
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 499177124 177 DErlkPKDYRQVDFDKRILLV-GNEDKGLNALLLKNADLKVKIPMNPKLNSLNVSVAVGIILF 238
Cdd:cd18103 82 EA---EKSLYDVDLTGPLALVlGSEGKGLRRLVLKNCDFLVKIPMAGKVDSLNVSVAAGIILY 141
|
|
| SpoU_methylase |
pfam00588 |
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet. |
98-238 |
1.48e-51 |
|
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet.
Pssm-ID: 425768 Cd Length: 142 Bit Score: 164.24 E-value: 1.48e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499177124 98 VMLHEIQDPHNFGAILRTCMAAEVDGIIF-KKHNQAPINSTVIRTSMGTVFYQNLVQVTNLSYAITTLQKHGFWTVATTL 176
Cdd:pfam00588 4 VVLDNIQDPGNLGAIIRTAAAFGADGLILvEPRSADPYNPKAIRASAGALFHLPLVVVDNLEEALKDLKEAGYAVVATSL 83
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 499177124 177 derlKPKDYRQVDFDKRILLV-GNEDKGLNALLLKNADLKVKIPMNPKLNSLNVSVAVGIILF 238
Cdd:pfam00588 84 ----GGKSLYEIDFPKKVALVfGNEGTGLSNEVLELCDRLVRIPMSGDVESLNVAVAAAIALY 142
|
|
| PRK11181 |
PRK11181 |
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB; |
33-238 |
3.32e-31 |
|
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB;
Pssm-ID: 183021 [Multi-domain] Cd Length: 244 Bit Score: 115.06 E-value: 3.32e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499177124 33 DKHQKLLGLIKKRGLRYEMHSSQWFHQQFRHINHQEFVCVINPNQMLKTiEQLIQITDSKSTSTLVMLHEIQDPHNFGAI 112
Cdd:PRK11181 34 KRLLPLINELEAQGIVIQLANRQTLDEKAEGAVHQGIIARVKPGRQLQE-NDLPDLLASLEQPFLLILDGVTDPHNLGAC 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499177124 113 LRTCMAAEVDGIIFKKHNQAPINSTVIRTSMGTVFYQNLVQVTNLSYAITTLQKHGFWTVATT--LDERLkpkdYrQVDF 190
Cdd:PRK11181 113 LRSADAAGVHAVIVPKDRSAQLNATAKKVACGAAETVPLIRVTNLARTMRMLQEKNIWIVGTAgeADHTL----Y-QSKL 187
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 499177124 191 DKRILLV-GNEDKGLNALLLKNADLKVKIPMNPKLNSLNVSVAVGIILF 238
Cdd:PRK11181 188 TGPLALVmGAEGEGMRRLTREHCDELISIPMAGSVSSLNVSVATGICLF 236
|
|
| SpoU_sub_bind |
smart00967 |
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose ... |
10-75 |
5.58e-08 |
|
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose methyltransferase substrate binding domain.
Pssm-ID: 214943 [Multi-domain] Cd Length: 70 Bit Score: 48.69 E-value: 5.58e-08
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499177124 10 LFGSKAFLEALDNQLQIKKV----NLSDKHQKLLGLIKKRGLRYEMHSSQWFHQQFRHINHQEFVCVINP 75
Cdd:smart00967 1 IEGRHAVEEALKSGRRIKELylteGRAERLKELLKLAKERGIKVIEVSKKELDKLSGTANHQGVVAVVKP 70
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| rRNA_methyl_3 |
TIGR00186 |
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases ... |
7-242 |
5.57e-115 |
|
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129290 [Multi-domain] Cd Length: 237 Bit Score: 328.53 E-value: 5.57e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499177124 7 TSFLFGSKAFLEALDNQ--LQIKKVNLSDKHQKLLGLIKKRGLRYEMHSSQWFHQQFRHINHQEFVCVINPnQMLKTIEQ 84
Cdd:TIGR00186 1 QEYLYGKNAVLEALLNQqrVFILKGLESKRLKKLIQLAKKQGINIQLVDRQKLDQLTKGGNHQGIAAKVKP-ILYKDLND 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499177124 85 LIQITDSKSTSTLVMLHEIQDPHNFGAILRTCMAAEVDGIIFKKHNQAPINSTVIRTSMGTVFYQNLVQVTNLSYAITTL 164
Cdd:TIGR00186 80 LYKTAKSKKQPFLLILDEITDPHNLGAILRTAEAFGVDGVILPKRRSAPLNSTVVKTSSGAVEYVPLARVTNLSRTITKL 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 499177124 165 QKHGFWTVATTLDERLkpKDYRQVDFDKRILLVGNEDKGLNALLLKNADLKVKIPMNPKLNSLNVSVAVGIILFGWKS 242
Cdd:TIGR00186 160 KESGFWTVGTDLDAQD--TLYQVKLTKPLALVVGNEGEGVSRLIKENCDFLIKIPMAGKVDSLNVSVAAGILLFEIKR 235
|
|
| SpoU |
COG0566 |
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA ... |
3-238 |
2.26e-77 |
|
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA G18 (ribose-2'-O)-methylase SpoU is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440332 [Multi-domain] Cd Length: 265 Bit Score: 234.32 E-value: 2.26e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499177124 3 RMQETSFL-FGSKAFLEALDNQLQIKKV----NLSDKHQKLLGLIKKRGLRYEMHSSQWFHQQFRHINHQEFVCVINPNQ 77
Cdd:COG0566 21 REEEGLFLaEGRHAVEEALKAGREIEELlvteGALDRLAELLALAKAAGIPVYEVSREVLDKLSGTETHQGVLAVVRPPE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499177124 78 MLkTIEQLIQitDSKSTSTLVMLHEIQDPHNFGAILRTCMAAEVDGIIFKKHNQAPINSTVIRTSMGTVFYQNLVQVTNL 157
Cdd:COG0566 101 YA-DLEDLLA--EAGEPPLLLVLDGVQDPGNLGAILRSAAAFGVDGVILPKRRADPYNPKVVRASAGALFHVPVARVTNL 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499177124 158 SYAITTLQKHGFWTVATTLDERlkpKDYRQVDFDKRILLV-GNEDKGLNALLLKNADLKVKIPMNPKLNSLNVSVAVGII 236
Cdd:COG0566 178 ADALEELKEAGFWVVGTDLDGE---ASLYEVDLPGPVALVlGNEGKGLSRLVLEACDELVRIPMAGGVESLNVAVAAAIL 254
|
..
gi 499177124 237 LF 238
Cdd:COG0566 255 LY 256
|
|
| SpoU-like_RlmB |
cd18103 |
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the ... |
97-238 |
3.28e-68 |
|
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the methylation of guanosine 2251, a modification conserved in the peptidyltransferase domain of 23S rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349976 Cd Length: 143 Bit Score: 206.47 E-value: 3.28e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499177124 97 LVMLHEIQDPHNFGAILRTCMAAEVDGIIFKKHNQAPINSTVIRTSMGTVFYQNLVQVTNLSYAITTLQKHGFWTVATTL 176
Cdd:cd18103 2 LLILDGITDPHNLGAIIRSAEAFGVDGVIIPKRRSAPLTPTVAKASAGALEHLPIARVTNLARALEELKEAGFWIYGADG 81
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 499177124 177 DErlkPKDYRQVDFDKRILLV-GNEDKGLNALLLKNADLKVKIPMNPKLNSLNVSVAVGIILF 238
Cdd:cd18103 82 EA---EKSLYDVDLTGPLALVlGSEGKGLRRLVLKNCDFLVKIPMAGKVDSLNVSVAAGIILY 141
|
|
| SpoU_methylase |
pfam00588 |
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet. |
98-238 |
1.48e-51 |
|
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet.
Pssm-ID: 425768 Cd Length: 142 Bit Score: 164.24 E-value: 1.48e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499177124 98 VMLHEIQDPHNFGAILRTCMAAEVDGIIF-KKHNQAPINSTVIRTSMGTVFYQNLVQVTNLSYAITTLQKHGFWTVATTL 176
Cdd:pfam00588 4 VVLDNIQDPGNLGAIIRTAAAFGADGLILvEPRSADPYNPKAIRASAGALFHLPLVVVDNLEEALKDLKEAGYAVVATSL 83
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 499177124 177 derlKPKDYRQVDFDKRILLV-GNEDKGLNALLLKNADLKVKIPMNPKLNSLNVSVAVGIILF 238
Cdd:pfam00588 84 ----GGKSLYEIDFPKKVALVfGNEGTGLSNEVLELCDRLVRIPMSGDVESLNVAVAAAIALY 142
|
|
| SpoU-like_rRNA-MTase |
cd18095 |
SAM-dependent rRNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
97-238 |
2.12e-51 |
|
SAM-dependent rRNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349968 Cd Length: 143 Bit Score: 163.75 E-value: 2.12e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499177124 97 LVMLHEIQDPHNFGAILRTCMAAEVDGIIFKKHNQAPINSTVIRTSMGTVFYQNLVQVTNLSYAITTLQKHGFWTVATTL 176
Cdd:cd18095 2 VLVLDGVQDPGNLGTIIRTAAAFGVDGVILSKGTVDPYNPKVVRASMGALFRLPIIRVDDLEELLEELKEAGYKVVAADL 81
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 499177124 177 DERlkpKDYRQVDFDKRILLV-GNEDKGLNALLLKNADLKVKIPMNPKLNSLNVSVAVGIILF 238
Cdd:cd18095 82 DGG---SSLYDLDLPKPVALVlGNEGNGLSDELLELCDKRVTIPMSGGVESLNVAVAAAILLY 141
|
|
| SpoU-like_MRM1 |
cd18105 |
SAM-dependent rRNA methylase related to MRM1; MRM1 catalyzes the methylation of 2'-O-ribose ... |
98-237 |
1.06e-34 |
|
SAM-dependent rRNA methylase related to MRM1; MRM1 catalyzes the methylation of 2'-O-ribose residues G1145 to GmG residue of the mitochondrial 16S rRNA. MRM1 is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349978 Cd Length: 158 Bit Score: 121.47 E-value: 1.06e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499177124 98 VMLHEIQDPHNFGAILRTCMAAEVDGIIFKKHNQAPINSTVIRTSMGTVFYQNLVQVTNLSYAITTLQKHGFWTVATTLD 177
Cdd:cd18105 3 LLLDEITDPQNLGAILRSAYFLGVDGVVVSSKNSAPLSPVVSKASAGALELMPIYSVDNLASFLKSSKENGWKVVGTSAP 82
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 499177124 178 E-------RLKPKDYRQVDFDKRILLV-GNEDKGLNALLLKNADLKVKIPM-----NPKLNSLNVSVAVGIIL 237
Cdd:cd18105 83 PsassdkkTIPANELSELLLEKPTILVlGNEGRGLRTNIKNLCDYLVSIPGgrsaeNPGVDSLNVSVAAGILL 155
|
|
| SpoU-like_RNA-MTase |
cd18104 |
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
97-238 |
2.92e-34 |
|
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349977 Cd Length: 146 Bit Score: 119.99 E-value: 2.92e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499177124 97 LVMLHEIQDPHNFGAILRTCMAAEVDGIIFKKHNQAPINSTVIRTSMGTVFYQNLVQVTNLSyAITTLQKHGFWTVATTL 176
Cdd:cd18104 2 ILVLEGLEKPGNLGAILRSADAAGADAVILCDPKTDLFNPNVIRASLGAVFTLPVAEASSEE-TLAWLKENKIRILATTP 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 499177124 177 DERlkpKDYRQVDFDKRI-LLVGNEDKGLNALLLKNADLKVKIPMNPKLNSLNVSVAVGIILF 238
Cdd:cd18104 81 KAE---KLYYEADLRGPIaIVVGSESEGLSEFWLKAADERVRIPMAGQADSLNVSVAAAILLY 140
|
|
| SpoU-like_family |
cd18082 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
98-240 |
6.55e-32 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349955 Cd Length: 145 Bit Score: 113.86 E-value: 6.55e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499177124 98 VMLHEIQDPHNFGAILRTCMAAEVDGIIFKKHNQAPINSTVIRTSMGTVFYQNLVQVTNLSYAITTLQKHGFWTVATTLD 177
Cdd:cd18082 2 LVLDNIRSPGNIGSIFRTADAFGVEKIYLVGPTADIFDPKAKRTSRGTHFSVPYERVDNFEEYLKSLKEEGYPLIGLELT 81
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 499177124 178 ERLKPKDYRQVDFDKRILLV-GNEDKGLNALLLKNADLKVKIPMNPKLNSLNVSVAVGIILFGW 240
Cdd:cd18082 82 DGSIPLSEFKFKKPKKIALIfGNERSGLSPELLALCDYTVHIPMSGKNSSLNVSVATGIALYEF 145
|
|
| PRK11181 |
PRK11181 |
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB; |
33-238 |
3.32e-31 |
|
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB;
Pssm-ID: 183021 [Multi-domain] Cd Length: 244 Bit Score: 115.06 E-value: 3.32e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499177124 33 DKHQKLLGLIKKRGLRYEMHSSQWFHQQFRHINHQEFVCVINPNQMLKTiEQLIQITDSKSTSTLVMLHEIQDPHNFGAI 112
Cdd:PRK11181 34 KRLLPLINELEAQGIVIQLANRQTLDEKAEGAVHQGIIARVKPGRQLQE-NDLPDLLASLEQPFLLILDGVTDPHNLGAC 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499177124 113 LRTCMAAEVDGIIFKKHNQAPINSTVIRTSMGTVFYQNLVQVTNLSYAITTLQKHGFWTVATT--LDERLkpkdYrQVDF 190
Cdd:PRK11181 113 LRSADAAGVHAVIVPKDRSAQLNATAKKVACGAAETVPLIRVTNLARTMRMLQEKNIWIVGTAgeADHTL----Y-QSKL 187
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 499177124 191 DKRILLV-GNEDKGLNALLLKNADLKVKIPMNPKLNSLNVSVAVGIILF 238
Cdd:PRK11181 188 TGPLALVmGAEGEGMRRLTREHCDELISIPMAGSVSSLNVSVATGICLF 236
|
|
| SpoU-like_TrmH |
cd18092 |
SAM-dependent tRNA methylase related to TrmH; TrmH catalyzes the transfer of the methyl group ... |
97-238 |
8.48e-28 |
|
SAM-dependent tRNA methylase related to TrmH; TrmH catalyzes the transfer of the methyl group from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of the ribose of the universally conserved guanosine 18 (G18) position in tRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349965 Cd Length: 162 Bit Score: 103.70 E-value: 8.48e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499177124 97 LVMLHEIQDPHNFGAILRTCMAAevdGI----IFKKHNQAPINStviRTSMGTVFYQNLVQVTNLSYAITTLQKHGFWTV 172
Cdd:cd18092 18 TVVLENVHDPHNASAVLRTCDAF---GVqdvhVIEPKNKFKKNR---GVAMGADKWLDVHRHDSTEECLAALKEQGYRIV 91
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 499177124 173 ATTLDERlkPKDYRQVDFDKRILLV-GNEDKGLNALLLKNADLKVKIPMNPKLNSLNVSVAVGIILF 238
Cdd:cd18092 92 ATSLSPD--AVPLDELDYTRPTALVfGNEKDGVSEEALAAADERVYIPMYGFVESLNVSVAAAIILY 156
|
|
| SpoU-like_RNA-MTase |
cd18109 |
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
97-240 |
5.06e-24 |
|
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349982 Cd Length: 141 Bit Score: 93.37 E-value: 5.06e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499177124 97 LVMLHEIQDPHNFGAILRTCMAAEVDGIIFKKHNQAPINSTVIRTSMGTVFYQNLVQvTNLSYAITTLQKHGFwTVATTL 176
Cdd:cd18109 2 TLALDGIQDPGNLGTIIRTADWFGIRQIICSPDTVDPYNPKVVQASMGSIFRVQIHY-TDLPALLAELKKAFP-VYGADL 79
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 499177124 177 DerlkPKDYRQVDF-DKRILLVGNEDKGLNALLLKNADLKVKIPMNPKL-NSLNVSVAVGIILFGW 240
Cdd:cd18109 80 D----GENLYEFTLpEKGILVMGNEGHGISPEVLKLLTHRLTIPRYGKGaESLNVAVATAILLSEF 141
|
|
| SpoU-like |
cd18097 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
98-238 |
6.27e-22 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349970 Cd Length: 144 Bit Score: 88.01 E-value: 6.27e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499177124 98 VMLHEIQDPHNFGAILRTCMAAEVDGIIFKKHNQAPINSTVIRTSMGTVFYQNLVQVTNLSYAITTLQKHGFWTVATTLD 177
Cdd:cd18097 3 VVLDNLRSAHNVGSIFRTADAAGVEKIYLCGYTPTPPHPKVAKTALGAEESVPWEHFEDTLEAVRALKARGYTIIALETT 82
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 499177124 178 ERLKPkdYRQVDFDKRILLV-GNEDKGLNALLLKNADLKVKIPMNPKLNSLNVSVAVGIILF 238
Cdd:cd18097 83 ENSVP--LHEARLPRPLALVlGNEVRGVSPEVLALCDAVVEIPMFGRKNSLNVAVAAAVALY 142
|
|
| SpoU-like_AviRb |
cd18107 |
SAM-dependent rRNA methylase related to AviRb; AviRb from Streptomyces viridochromogenes ... |
105-238 |
3.23e-19 |
|
SAM-dependent rRNA methylase related to AviRb; AviRb from Streptomyces viridochromogenes methylates the 2'-O atom of U2479 of the 23S ribosomal RNA. AviRb is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349980 Cd Length: 148 Bit Score: 80.90 E-value: 3.23e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499177124 105 DPHNFGAILRTCMAAEVDGIIFKKHNQAPINSTVIRTSMGTVFYQNLVQVT----------NLSYAITTLQkhgfwTVAT 174
Cdd:cd18107 10 SPGNLGTIIRSADALGAHGLVVTGHAADVYDPKTIRASTGSLFSLPIVRVPsnreledwveARKARGTPLQ-----LVGT 84
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 499177124 175 TL--DERLKPKDYRQvdfdKRILLVGNEDKGLNALLLKNADLKVKIPMNPKLNSLNVSVAVGIILF 238
Cdd:cd18107 85 DEhgDHQIADHDFTR----PTLLLIGNETAGLSAAWRELCDETVSIPMAGSASSLNAACAASIFLY 146
|
|
| PRK11081 |
PRK11081 |
tRNA guanosine-2'-O-methyltransferase; Provisional |
76-238 |
2.24e-16 |
|
tRNA guanosine-2'-O-methyltransferase; Provisional
Pssm-ID: 236837 [Multi-domain] Cd Length: 229 Bit Score: 75.41 E-value: 2.24e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499177124 76 NQMLktieqliqitDSKSTSTLVMLHEIQDPHNFGAILRTCMAAEVDGIifkkHNQAPINSTVIR--TSMGTvfyQNLVQ 153
Cdd:PRK11081 10 CEML----------ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEV----HAVWPGSRMRTMgsTAAGS---NSWVQ 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499177124 154 V---TNLSYAITTLQKHGFWTVATTLDErlKPKDYRQVDFDK-RILLVGNEDKGLNALLLKNADLKVKIPMNPKLNSLNV 229
Cdd:PRK11081 73 VkthRTIGDAVAHLKGQGMQILATHLSD--TAVDFREIDYTRpTCILMGQEKTGISQEALALADQDIIIPMIGMVQSLNV 150
|
....*....
gi 499177124 230 SVAVGIILF 238
Cdd:PRK11081 151 SVASALILY 159
|
|
| SpoU-like_RNMTL1 |
cd18106 |
SAM-dependent rRNA methylase related to RNMTL1; RNMTL1 (also known as HC90, MRM3 and RMTL1) ... |
103-238 |
2.39e-15 |
|
SAM-dependent rRNA methylase related to RNMTL1; RNMTL1 (also known as HC90, MRM3 and RMTL1) catalyzes the methylation of 2'-O-ribose residues G1370 to GmG residue of the mitochondrial 16S rRNA. RNMTL1 is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349979 Cd Length: 148 Bit Score: 70.74 E-value: 2.39e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499177124 103 IQDPHNFGAILRTCMAAEVDGIIFKKHNQAPINSTVIRTSMGTVF----YQNLV--QVTNLSYAITTLqkhgfwTVAttl 176
Cdd:cd18106 8 IRDPGNLGSILRSAAAAGCSKVLLTKGCVDPWEPKVLRAGAGAHFrlpiYGNLSwdDIPNYLPDDSKV------FLA--- 78
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 499177124 177 DERLKPKDYRQVDFDKR--ILLVGNEDKGL--NALLLKNAD--LKVKIPMNPKLNSLNVSVAVGIILF 238
Cdd:cd18106 79 DNNLPVQPYDSIDYCSGpiVLVIGGETHGVspEAYKLAHSTggSRVHIPLANGVDSLNSAVAASILLF 146
|
|
| PRK10864 |
PRK10864 |
putative methyltransferase; Provisional |
97-240 |
1.09e-14 |
|
putative methyltransferase; Provisional
Pssm-ID: 236779 [Multi-domain] Cd Length: 346 Bit Score: 72.12 E-value: 1.09e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499177124 97 LVMLHEIQDPHNFGAILRTCMAAEVDGIIFKkhNQAPINS-TVIRTSMGTVFYQNLVQVTNLSYAITTLQKHGFwTVATT 175
Cdd:PRK10864 200 VLALEDVGNPHNLGGIMRSCAHFGVKGVVVQ--DAALLESgAAIRTAEGGAEHVQPITGDSFVDVLDDFRQAGY-TIVTT 276
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 499177124 176 LDERLKPKdYRQVDFDKRILLVGNEDKGLNALLLKNADLKVKIPMNPKLNSLNVSVAVGIILFGW 240
Cdd:PRK10864 277 SSHKGTPL-FKASLPAKMVLVLGQEYDGLSDAARQQGDLSVSIDGTGNVESLNVSVATGVLLAEW 340
|
|
| SpoU-like_TrmL |
cd18094 |
SAM-dependent tRNA methylase related to TrmL; tRNA (Um34/Cm34) methyltransferase TrmL ... |
98-238 |
1.41e-12 |
|
SAM-dependent tRNA methylase related to TrmL; tRNA (Um34/Cm34) methyltransferase TrmL catalyzes the methyl transfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH at position 34 in both tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349967 Cd Length: 145 Bit Score: 63.24 E-value: 1.41e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499177124 98 VMLHEIQDPHNFGAILRTCMAAEVDGIIFKkhnqaPI-----NSTVIRTSMGTVFYQNLVQVTNLS-----------YAI 161
Cdd:cd18094 2 IVLYEPEIPQNTGNIARTCAATGARLHLIE-----PLgfsldDKRLKRAGLDYWDHVDLTVHDSWEaflealppgrlFLF 76
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 499177124 162 TTLQKHGFWtvattlDERLKPKDYrqvdfdkriLLVGNEDKGL-NALLLKNADLKVKIPMNPKLNSLNVSVAVGIILF 238
Cdd:cd18094 77 TTKGTKPYT------DFDFKPGDY---------LVFGRESTGLpEEILDAFPDRRLRIPMRPKVRSLNLSNSVAIVLY 139
|
|
| TrmL |
COG0219 |
tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain [Translation, ... |
99-238 |
3.26e-12 |
|
tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain [Translation, ribosomal structure and biogenesis]; tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 439989 Cd Length: 153 Bit Score: 62.36 E-value: 3.26e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499177124 99 MLH------EIqdPHNFGAILRTCMA--AEVDgII----FK---KHnqapinstVIRTSMGtvfYQNLVQVT---NLSYA 160
Cdd:COG0219 1 MLHivlyepEI--PQNTGNIIRLCAAtgARLH-LIeplgFSlddKK--------LKRAGLD---YWELVDLTvhdSWEAF 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499177124 161 ITTLQKHGFWtVATTlderlK-PKDYRQVDF-DKRILLVGNEDKGL-NALLLKNADLKVKIPMNPKLNSLNVSVAVGIIL 237
Cdd:COG0219 67 LEALPGGRLF-LFTT-----KgTKPYTDVDYqPGDVLLFGRETAGLpEEVLAAPADQRLRIPMRPGVRSLNLSNAVAIVL 140
|
.
gi 499177124 238 F 238
Cdd:COG0219 141 Y 141
|
|
| SpoU_sub_bind |
pfam08032 |
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose ... |
9-77 |
4.74e-12 |
|
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose methyltransferase substrate binding domain.
Pssm-ID: 429793 [Multi-domain] Cd Length: 74 Bit Score: 59.95 E-value: 4.74e-12
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 499177124 9 FLFGSKAFLEALDNQLQIKKVNLSDKH-----QKLLGLIKKRGLRYEMHSSQWFHQQFRHINHQEFVCVINPNQ 77
Cdd:pfam08032 1 LIYGRHAVLEALKSGPEIKKLYLTEGRrdprlKELLKLAKERGIKVEEVDRKKLDKLSGTANHQGVVAEVKPYE 74
|
|
| SpoU-like_NHR |
cd18108 |
Nosiheptide-resistance methyltransferase (NHR); Nosiheptide-resistance methyltransferase (NHR) ... |
108-238 |
4.33e-10 |
|
Nosiheptide-resistance methyltransferase (NHR); Nosiheptide-resistance methyltransferase (NHR) confers resistance to the thiazole antibiotic nosiheptide via catalyzing 2'O-methylation of 23S rRNA at the nucleotide A1067. NHR is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349981 Cd Length: 144 Bit Score: 56.33 E-value: 4.33e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499177124 108 NFGAILRTCMAAEVDGIIFKKHNQAPI-NSTVIRTSMGTVFYQNLVqVTNLSYAITTLQKHGFWTVATTLDERLKPKDYR 186
Cdd:cd18108 13 NIGAIVRTSLALGAAGIVLVDSDLATVaDRRLLRASRGYVFSLPVV-LADREEAVAFLRDNDIPLMTLDADGDVPVKELG 91
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 499177124 187 QVDfDKRILLVGNEDKGLNALLLKNADLKVKIPMNPKLNSLNVSVAVGIILF 238
Cdd:cd18108 92 DRP-DRLALVFGSEKGGPSGLFEEAAAGTVSIPMSSSTESLNVSVSAGIALH 142
|
|
| SpoU-like_TrmJ |
cd18093 |
SAM-dependent tRNA methylase related to TrmJ; tRNA methyltransferase TrmJ catalyzes the methyl ... |
98-240 |
9.10e-10 |
|
SAM-dependent tRNA methylase related to TrmJ; tRNA methyltransferase TrmJ catalyzes the methyl transfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH at position 32 in both tRNASer1 and tRNAGln2. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349966 Cd Length: 153 Bit Score: 55.58 E-value: 9.10e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499177124 98 VMLHEIQDPHNFGAILRTCMAAEVDGIIFKKHNQAPINSTVIRTSMGTVFY-QNLVQVTNLSYAIttlqkHGF-WTVATT 175
Cdd:cd18093 3 VVLVEPQHPGNIGAVARAMKNFGLSDLRLVNPRCDDPEEAARALASGAEDVlENAKVYDTLEEAL-----ADCdLVVATT 77
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 499177124 176 ----------LDERLKPKDYRQVDFDKRI-LLVGNEDKGLNALLLKNADLKVKIPMNPKLNSLNVSVAVGIILFGW 240
Cdd:cd18093 78 arprglrrplLTPRELAELLKEHAAGGKVaLVFGREDSGLTNEELALCDLLVTIPTNPEYPSLNLAQAVAIVLYEL 153
|
|
| SpoU-like |
cd18096 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
98-240 |
4.13e-08 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349969 Cd Length: 140 Bit Score: 50.68 E-value: 4.13e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499177124 98 VMLHEIQDPHNFGAILRTCMAAEVDGIIF---KKHNQAPinstvirtSMGTVFYQNLVQVTNLSYAITTLQKHGFWTV-- 172
Cdd:cd18096 3 LVLHNVAKRHNIGTIVRSANAFGVKEVHLvgrRKFNPFG--------AMGTDRHVKFRHFDTLAEAKEYLKERGIRLVgv 74
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 499177124 173 -----ATTLDERLKPKDyrqvdfdkRILLVGNEDKGLNALLLKNADLKVKIPMN-PKLNSLNVSVAVGIILFGW 240
Cdd:cd18096 75 eivpgAEPIETHPFPGD--------TAFVLGNEGTGLSDEQLAICDGFVYIPQYgSGTASLNVSVAASIVLHHF 140
|
|
| SpoU_sub_bind |
smart00967 |
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose ... |
10-75 |
5.58e-08 |
|
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose methyltransferase substrate binding domain.
Pssm-ID: 214943 [Multi-domain] Cd Length: 70 Bit Score: 48.69 E-value: 5.58e-08
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499177124 10 LFGSKAFLEALDNQLQIKKV----NLSDKHQKLLGLIKKRGLRYEMHSSQWFHQQFRHINHQEFVCVINP 75
Cdd:smart00967 1 IEGRHAVEEALKSGRRIKELylteGRAERLKELLKLAKERGIKVIEVSKKELDKLSGTANHQGVVAVVKP 70
|
|
| SpoU-like_TRM3-like |
cd18091 |
SAM-dependent tRNA methylase related to TRM3; Yeast tRNA (guanosine(18)-2'-O) ... |
103-240 |
1.68e-04 |
|
SAM-dependent tRNA methylase related to TRM3; Yeast tRNA (guanosine(18)-2'-O)-methyltransferase TRM3 catalyzes the formation of 2'-O-methylguanosine at position 18 (Gm18) in various tRNAs. TRM3 is similar to C-terminal domain of TAR (HIV-1) RNA binding protein 1 (TARBP1), a protein binding to TAR, which functions as a RNA regulatory signal by forming a stable stem-loop structure to which transactivator protein Tat binds. The role of TARBP1 is believed to be to disengage RNA polymerase II from TAR during transcriptional elongation. TRM3 and the C-terminal methyltransferase domain of TARBP1 are members of the SPOUT methyltransferase superfamily.
Pssm-ID: 349964 Cd Length: 145 Bit Score: 40.59 E-value: 1.68e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499177124 103 IQDPHNFGAILRTCMAAEVDGIIFkkHNQAPINSTVIRT-SMGTVFYQNLVQVT--NLSYAITTLQKHGFWTVA---TTL 176
Cdd:cd18091 8 IDKPPNLGGLCRTCEIFGVSKLVL--PNLAVVEDKQFKAlSVSAEKWLPIEEVKpeDLLPYLKEKKQEGYTIVGleqTAN 85
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 499177124 177 DERLKpkDYrqvDFDKR-ILLVGNEDKGLNALLLKNADLKVKIPMNPKLNSLNVSVAVGIILFGW 240
Cdd:cd18091 86 SVSLH--DF---QFPKKtVLVLGNEKEGIPAELLSLLDVCVEIPQLGVIRSLNVHVSGAIAIYEY 145
|
|
| TrmJ |
COG0565 |
tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase [Translation, ... |
98-240 |
3.08e-04 |
|
tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase [Translation, ribosomal structure and biogenesis]; tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440331 [Multi-domain] Cd Length: 237 Bit Score: 40.87 E-value: 3.08e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499177124 98 VMLHEIQDPHNFGAILRTCMaaevdgiifkkhN-----------QAPINSTVIRTSMGTVFY-QNLVQVTNLSYAITTLQ 165
Cdd:COG0565 6 VVLVEPQHPGNIGAAARAMK------------NfglsdlrlvnpRGWPDEEARAMASGADDVlENARVVDTLEEALADCD 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499177124 166 khgfWTVATT--LDERLKP--------KDYRQVDFDKRILLV-GNEDKGLNalllkNADLK-----VKIPMNPKLNSLNV 229
Cdd:COG0565 74 ----LVVGTTarPRELRKPvltpreaaEELLARAAGGKVALVfGRERSGLT-----NEELAlcdalVTIPTNPEYPSLNL 144
|
170
....*....|.
gi 499177124 230 SVAVGIILFGW 240
Cdd:COG0565 145 AQAVQVVAYEL 155
|
|
| |
