|
Name |
Accession |
Description |
Interval |
E-value |
| HisP |
COG4598 |
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism]; |
2-253 |
0e+00 |
|
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443652 [Multi-domain] Cd Length: 259 Bit Score: 524.75 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 2 TTPAISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEMKPNRKGQNRP 81
Cdd:COG4598 5 APPALEVRDLHKSFGDLEVLKGVSLTARKGDVISIIGSSGSGKSTFLRCINLLETPDSGEIRVGGEEIRLKPDRDGELVP 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 82 SNLKQIDRIRTQLGMVFQNFNLWSHKTVLENIIEAPVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAA 161
Cdd:COG4598 85 ADRRQLQRIRTRLGMVFQSFNLWSHMTVLENVIEAPVHVLGRPKAEAIERAEALLAKVGLADKRDAYPAHLSGGQQQRAA 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 162 IARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVFTA 241
Cdd:COG4598 165 IARALAMEPEVMLFDEPTSALDPELVGEVLKVMRDLAEEGRTMLVVTHEMGFARDVSSHVVFLHQGRIEEQGPPAEVFGN 244
|
250
....*....|..
gi 497963481 242 SQSARFRQFIAS 253
Cdd:COG4598 245 PKSERLRQFLSS 256
|
|
| GlnQ |
COG1126 |
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ... |
6-252 |
1.90e-162 |
|
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440743 [Multi-domain] Cd Length: 239 Bit Score: 449.06 E-value: 1.90e-162
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEMKPnrkgqnrpsnlK 85
Cdd:COG1126 2 IEIENLHKSFGDLEVLKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVDGEDLTDSK-----------K 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 86 QIDRIRTQLGMVFQNFNLWSHKTVLENIIEAPVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIARA 165
Cdd:COG1126 71 DINKLRRKVGMVFQQFNLFPHLTVLENVTLAPIKVKKMSKAEAEERAMELLERVGLADKADAYPAQLSGGQQQRVAIARA 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 166 LAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVFTASQSA 245
Cdd:COG1126 151 LAMEPKVMLFDEPTSALDPELVGEVLDVMRDLAKEGMTMVVVTHEMGFAREVADRVVFMDGGRIVEEGPPEEFFENPQHE 230
|
....*..
gi 497963481 246 RFRQFIA 252
Cdd:COG1126 231 RTRAFLS 237
|
|
| ABC_HisP_GlnQ |
cd03262 |
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ... |
6-229 |
1.24e-132 |
|
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.
Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 373.02 E-value: 1.24e-132
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIemkpnrkgqnrPSNLK 85
Cdd:cd03262 1 IEIKNLHKSFGDFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKL-----------TDDKK 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 86 QIDRIRTQLGMVFQNFNLWSHKTVLENIIEAPVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIARA 165
Cdd:cd03262 70 NINELRQKVGMVFQQFNLFPHLTVLENITLAPIKVKGMSKAEAEERALELLEKVGLADKADAYPAQLSGGQQQRVAIARA 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 497963481 166 LAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEI 229
Cdd:cd03262 150 LAMNPKVMLFDEPTSALDPELVGEVLDVMKDLAEEGMTMVVVTHEMGFAREVADRVIFMDDGRI 213
|
|
| PRK10619 |
PRK10619 |
histidine ABC transporter ATP-binding protein HisP; |
1-252 |
1.18e-112 |
|
histidine ABC transporter ATP-binding protein HisP;
Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 324.23 E-value: 1.18e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 1 MTTPAISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEMKPNRKGQNR 80
Cdd:PRK10619 1 MSENKLNVIDLHKRYGEHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTINLVRDKDGQLK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 81 PSNLKQIDRIRTQLGMVFQNFNLWSHKTVLENIIEAPVHVLKRPQAECVEHAEQLLEKVGLADK-RHYYPAHLSGGQQQR 159
Cdd:PRK10619 81 VADKNQLRLLRTRLTMVFQHFNLWSHMTVLENVMEAPIQVLGLSKQEARERAVKYLAKVGIDERaQGKYPVHLSGGQQQR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 160 AAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVF 239
Cdd:PRK10619 161 VSIARALAMEPEVLLFDEPTSALDPELVGEVLRIMQQLAEEGKTMVVVTHEMGFARHVSSHVIFLHQGKIEEEGAPEQLF 240
|
250
....*....|...
gi 497963481 240 TASQSARFRQFIA 252
Cdd:PRK10619 241 GNPQSPRLQQFLK 253
|
|
| glnQ |
PRK09493 |
glutamine ABC transporter ATP-binding protein GlnQ; |
6-251 |
1.18e-105 |
|
glutamine ABC transporter ATP-binding protein GlnQ;
Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 305.48 E-value: 1.18e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIemkpnrkgqNRPSnlK 85
Cdd:PRK09493 2 IEFKNVSKHFGPTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKV---------NDPK--V 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 86 QIDRIRTQLGMVFQNFNLWSHKTVLENIIEAPVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIARA 165
Cdd:PRK09493 71 DERLIRQEAGMVFQQFYLFPHLTALENVMFGPLRVRGASKEEAEKQARELLAKVGLAERAHHYPSELSGGQQQRVAIARA 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 166 LAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVFTASQSA 245
Cdd:PRK09493 151 LAVKPKLMLFDEPTSALDPELRHEVLKVMQDLAEEGMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDGDPQVLIKNPPSQ 230
|
....*.
gi 497963481 246 RFRQFI 251
Cdd:PRK09493 231 RLQEFL 236
|
|
| PRK11264 |
PRK11264 |
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional |
5-251 |
3.79e-104 |
|
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 302.05 E-value: 3.79e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 5 AISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEMKPNRKGQNRpsnl 84
Cdd:PRK11264 3 AIEVKNLVKKFHGQTVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIRVGDITIDTARSLSQQKG---- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 85 kQIDRIRTQLGMVFQNFNLWSHKTVLENIIEAPVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIAR 164
Cdd:PRK11264 79 -LIRQLRQHVGFVFQNFNLFPHRTVLENIIEGPVIVKGEPKEEATARARELLAKVGLAGKETSYPRRLSGGQQQRVAIAR 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 165 ALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVFTASQS 244
Cdd:PRK11264 158 ALAMRPEVILFDEPTSALDPELVGEVLNTIRQLAQEKRTMVIVTHEMSFARDVADRAIFMDQGRIVEQGPAKALFADPQQ 237
|
....*..
gi 497963481 245 ARFRQFI 251
Cdd:PRK11264 238 PRTRQFL 244
|
|
| ArtP |
COG4161 |
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism]; |
5-252 |
9.43e-97 |
|
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443326 [Multi-domain] Cd Length: 242 Bit Score: 283.06 E-value: 9.43e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 5 AISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEMkpnrkgqNRPSNL 84
Cdd:COG4161 2 SIQLKNINCFYGSHQALFDINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAGHQFDF-------SQKPSE 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 85 KQIDRIRTQLGMVFQNFNLWSHKTVLENIIEAPVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIAR 164
Cdd:COG4161 75 KAIRLLRQKVGMVFQQYNLWPHLTVMENLIEAPCKVLGLSKEQAREKAMKLLARLRLTDKADRFPLHLSGGQQQRVAIAR 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 165 ALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHvFTASQS 244
Cdd:COG4161 155 ALMMEPQVLLFDEPTAALDPEITAQVVEIIRELSQTGITQVIVTHEVEFARKVASQVVYMEKGRIIEQGDASH-FTQPQT 233
|
....*...
gi 497963481 245 ARFRQFIA 252
Cdd:COG4161 234 EAFAHYLS 241
|
|
| ectoine_ehuA |
TIGR03005 |
ectoine/hydroxyectoine ABC transporter, ATP-binding protein; Members of this family are the ... |
6-253 |
3.10e-96 |
|
ectoine/hydroxyectoine ABC transporter, ATP-binding protein; Members of this family are the ATP-binding protein of a conserved four gene ABC transporter operon found next to ectoine unilization operons and ectoine biosynthesis operons. Ectoine is a compatible solute that protects enzymes from high osmolarity. It is released by some species in response to hypoosmotic shock, and it is taken up by a number of bacteria as a compatible solute or for consumption. This family shows strong sequence similiarity to a number of amino acid ABC transporter ATP-binding proteins.
Pssm-ID: 132050 [Multi-domain] Cd Length: 252 Bit Score: 282.10 E-value: 3.10e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEMKPNRKGQNRPSNLK 85
Cdd:TIGR03005 1 VRFSDVTKRFGILTVLDGLNFSVAAGEKVALIGPSGSGKSTILRILMTLEPIDEGQIQVEGEQLYHMPGRNGPLVPADEK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 86 QIDRIRTQLGMVFQNFNLWSHKTVLENIIEAPVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIARA 165
Cdd:TIGR03005 81 HLRQMRNKIGMVFQSFNLFPHKTVLDNVTEAPVLVLGMARAEAEKRAMELLDMVGLADKADHMPAQLSGGQQQRVAIARA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 166 LAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVFTASQS 244
Cdd:TIGR03005 161 LAMRPKVMLFDEVTSALDPELVGEVLNVIRRLASEhDLTMLLVTHEMGFAREFADRVCFFDKGRIVEQGKPDEIFRQPKE 240
|
....*....
gi 497963481 245 ARFRQFIAS 253
Cdd:TIGR03005 241 ERTREFLSK 249
|
|
| artP |
PRK11124 |
arginine transporter ATP-binding subunit; Provisional |
5-252 |
1.25e-93 |
|
arginine transporter ATP-binding subunit; Provisional
Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 275.35 E-value: 1.25e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 5 AISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEMKpnrkgqnRPSNL 84
Cdd:PRK11124 2 SIQLNGINCFYGAHQALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGNHFDFS-------KTPSD 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 85 KQIDRIRTQLGMVFQNFNLWSHKTVLENIIEAPVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIAR 164
Cdd:PRK11124 75 KAIRELRRNVGMVFQQYNLWPHLTVQQNLIEAPCRVLGLSKDQALARAEKLLERLRLKPYADRFPLHLSGGQQQRVAIAR 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 165 ALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHvFTASQS 244
Cdd:PRK11124 155 ALMMEPQVLLFDEPTAALDPEITAQIVSIIRELAETGITQVIVTHEVEVARKTASRVVYMENGHIVEQGDASC-FTQPQT 233
|
....*...
gi 497963481 245 ARFRQFIA 252
Cdd:PRK11124 234 EAFKNYLS 241
|
|
| AbcC |
COG1135 |
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism]; |
6-253 |
1.88e-89 |
|
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 268.10 E-value: 1.88e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSF----GSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIemkpnrkgqnrp 81
Cdd:COG1135 2 IELENLSKTFptkgGPVTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGVDL------------ 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 82 SNL--KQIDRIRTQLGMVFQNFNLWSHKTVLENIiEAPVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQR 159
Cdd:COG1135 70 TALseRELRAARRKIGMIFQHFNLLSSRTVAENV-ALPLEIAGVPKAEIRKRVAELLELVGLSDKADAYPSQLSGGQKQR 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 160 AAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHV 238
Cdd:COG1135 149 VGIARALANNPKVLLCDEATSALDPETTRSILDLLKDINRElGLTIVLITHEMDVVRRICDRVAVLENGRIVEQGPVLDV 228
|
250
....*....|....*
gi 497963481 239 FTASQSARFRQFIAS 253
Cdd:COG1135 229 FANPQSELTRRFLPT 243
|
|
| ABC_MetN_methionine_transporter |
cd03258 |
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ... |
6-243 |
5.42e-87 |
|
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 257.89 E-value: 5.42e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGS----LDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEMKPNRKGQNrp 81
Cdd:cd03258 2 IELKNVSKVFGDtggkVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDLTLLSGKELRK-- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 82 snlkqidrIRTQLGMVFQNFNLWSHKTVLENIiEAPVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAA 161
Cdd:cd03258 80 --------ARRRIGMIFQHFNLLSSRTVFENV-ALPLEIAGVPKAEIEERVLELLELVGLEDKADAYPAQLSGGQKQRVG 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 162 IARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVFT 240
Cdd:cd03258 151 IARALANNPKVLLCDEATSALDPETTQSILALLRDINRElGLTIVLITHEMEVVKRICDRVAVMEKGEVVEEGTVEEVFA 230
|
...
gi 497963481 241 ASQ 243
Cdd:cd03258 231 NPQ 233
|
|
| MlaF |
COG1127 |
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ... |
1-251 |
4.22e-86 |
|
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 256.06 E-value: 4.22e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 1 MTTPAISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAI-EMKPnrkgqn 79
Cdd:COG1127 1 MSEPMIEVRNLTKSFGDRVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGQDItGLSE------ 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 80 rpsnlKQIDRIRTQLGMVFQNFNLWSHKTVLENIiEAPVHVLKR-PQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQ 158
Cdd:COG1127 75 -----KELYELRRRIGMLFQGGALFDSLTVFENV-AFPLREHTDlSEAEIRELVLEKLELVGLPGAADKMPSELSGGMRK 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 159 RAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEH 237
Cdd:COG1127 149 RVALARALALDPEILLYDEPTAGLDPITSAVIDELIRELRDElGLTSVVVTHDLDSAFAIADRVAVLADGKIIAEGTPEE 228
|
250
....*....|....
gi 497963481 238 VFtASQSARFRQFI 251
Cdd:COG1127 229 LL-ASDDPWVRQFL 241
|
|
| LolD |
COG1136 |
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]; |
3-232 |
3.38e-83 |
|
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440751 [Multi-domain] Cd Length: 227 Bit Score: 248.03 E-value: 3.38e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 3 TPAISLRNIHKSFGS----LDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIemkpnrkgq 78
Cdd:COG1136 2 SPLLELRNLTKSYGTgegeVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDI--------- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 79 nrpSNL--KQIDRIR-TQLGMVFQNFNLWSHKTVLENIiEAPVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGG 155
Cdd:COG1136 73 ---SSLseRELARLRrRHIGFVFQFFNLLPELTALENV-ALPLLLAGVSRKERRERARELLERVGLGDRLDHRPSQLSGG 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 497963481 156 QQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFArEVSNRIVFLHQGEIEEQ 232
Cdd:COG1136 149 QQQRVAIARALVNRPKLILADEPTGNLDSKTGEEVLELLRELNRElGTTIVMVTHDPELA-ARADRVIRLRDGRIVSD 225
|
|
| ABC_MJ0796_LolCDE_FtsE |
cd03255 |
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ... |
6-229 |
8.25e-81 |
|
ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.
Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 241.63 E-value: 8.25e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLD----VLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIemkpnrkgqNRP 81
Cdd:cd03255 1 IELKNLSKTYGGGGekvqALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDI---------SKL 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 82 SNLKQIDRIRTQLGMVFQNFNLWSHKTVLENIiEAPVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAA 161
Cdd:cd03255 72 SEKELAAFRRRHIGFVFQSFNLLPDLTALENV-ELPLLLAGVPKKERRERAEELLERVGLGDRLNHYPSELSGGQQQRVA 150
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 497963481 162 IARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSnRIVFLHQGEI 229
Cdd:cd03255 151 IARALANDPKIILADEPTGNLDSETGKEVMELLRELNKEaGTTIVVVTHDPELAEYAD-RIIELRDGKI 218
|
|
| PotA |
COG3842 |
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ... |
1-247 |
1.71e-80 |
|
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 245.78 E-value: 1.71e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 1 MTTPAISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAI-EMKPNRkgqn 79
Cdd:COG3842 1 MAMPALELENVSKRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVtGLPPEK---- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 80 RPsnlkqidrirtqLGMVFQNFNLWSHKTVLENIiEAPVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQR 159
Cdd:COG3842 77 RN------------VGMVFQDYALFPHLTVAENV-AFGLRMRGVPKAEIRARVAELLELVGLEGLADRYPHQLSGGQQQR 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 160 AAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTL-ADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHV 238
Cdd:COG3842 144 VALARALAPEPRVLLLDEPLSALDAKLREEMREELRRLqRELGITFIYVTHDQEEALALADRIAVMNDGRIEQVGTPEEI 223
|
250
....*....|..
gi 497963481 239 FTASQS---ARF 247
Cdd:COG3842 224 YERPATrfvADF 235
|
|
| ABC_Org_Solvent_Resistant |
cd03261 |
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ... |
6-250 |
2.83e-77 |
|
ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 233.55 E-value: 2.83e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAI-EMKPnrkgqnrpsnl 84
Cdd:cd03261 1 IELRGLTKSFGGRTVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDIsGLSE----------- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 85 KQIDRIRTQLGMVFQNFNLWSHKTVLENIiEAPVHV-LKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIA 163
Cdd:cd03261 70 AELYRLRRRMGMLFQSGALFDSLTVFENV-AFPLREhTRLSEEEIREIVLEKLEAVGLRGAEDLYPAELSGGMKKRVALA 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 164 RALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVFtAS 242
Cdd:cd03261 149 RALALDPELLLYDEPTAGLDPIASGVIDDLIRSLKKElGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGTPEELR-AS 227
|
....*...
gi 497963481 243 QSARFRQF 250
Cdd:cd03261 228 DDPLVRQF 235
|
|
| EcfA2 |
COG1122 |
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ... |
6-240 |
3.85e-75 |
|
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 227.60 E-value: 3.85e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSF-GSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIemkpnrkgqnRPSNL 84
Cdd:COG1122 1 IELENLSFSYpGGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDI----------TKKNL 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 85 KQIdriRTQLGMVFQN-----FNlwshKTVLENIIEAPVHvLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQR 159
Cdd:COG1122 71 REL---RRKVGLVFQNpddqlFA----PTVEEDVAFGPEN-LGLPREEIRERVEEALELVGLEHLADRPPHELSGGQKQR 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 160 AAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVF 239
Cdd:COG1122 143 VAIAGVLAMEPEVLVLDEPTAGLDPRGRRELLELLKRLNKEGKTVIIVTHDLDLVAELADRVIVLDDGRIVADGTPREVF 222
|
.
gi 497963481 240 T 240
Cdd:COG1122 223 S 223
|
|
| metN |
PRK11153 |
DL-methionine transporter ATP-binding subunit; Provisional |
6-253 |
4.51e-75 |
|
DL-methionine transporter ATP-binding subunit; Provisional
Pssm-ID: 236863 [Multi-domain] Cd Length: 343 Bit Score: 231.61 E-value: 4.51e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSF----GSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIemkpnrkgqnrp 81
Cdd:PRK11153 2 IELKNISKVFpqggRTIHALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQDL------------ 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 82 SNL--KQIDRIRTQLGMVFQNFNLWSHKTVLENIieA-PVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQ 158
Cdd:PRK11153 70 TALseKELRKARRQIGMIFQHFNLLSSRTVFDNV--AlPLELAGTPKAEIKARVTELLELVGLSDKADRYPAQLSGGQKQ 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 159 RAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEH 237
Cdd:PRK11153 148 RVAIARALASNPKVLLCDEATSALDPATTRSILELLKDINRElGLTIVLITHEMDVVKRICDRVAVIDAGRLVEQGTVSE 227
|
250
....*....|....*.
gi 497963481 238 VFTASQSARFRQFIAS 253
Cdd:PRK11153 228 VFSHPKHPLTREFIQS 243
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
1-245 |
1.14e-74 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 235.57 E-value: 1.14e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 1 MTTPAISLRNIHKSF-----GSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIemkpnr 75
Cdd:COG1123 256 AAEPLLEVRNLSKRYpvrgkGGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDGKDL------ 329
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 76 kgqnRPSNLKQIDRIRTQLGMVFQN----FNlwSHKTVLEnIIEAPVHVLKR-PQAECVEHAEQLLEKVGL-ADKRHYYP 149
Cdd:COG1123 330 ----TKLSRRSLRELRRRVQMVFQDpyssLN--PRMTVGD-IIAEPLRLHGLlSRAERRERVAELLERVGLpPDLADRYP 402
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 150 AHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQGE 228
Cdd:COG1123 403 HELSGGQRQRVAIARALALEPKLLILDEPTSALDVSVQAQILNLLRDLQRElGLTYLFISHDLAVVRYIADRVAVMYDGR 482
|
250
....*....|....*..
gi 497963481 229 IEEQGTPEHVFTASQSA 245
Cdd:COG1123 483 IVEDGPTEEVFANPQHP 499
|
|
| PhnC |
COG3638 |
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ... |
4-238 |
5.49e-74 |
|
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 442855 [Multi-domain] Cd Length: 249 Bit Score: 225.32 E-value: 5.49e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 4 PAISLRNIHKSF-GSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIemkpnrkGQNRPS 82
Cdd:COG3638 1 PMLELRNLSKRYpGGTPALDDVSLEIERGEFVALIGPSGAGKSTLLRCLNGLVEPTSGEILVDGQDV-------TALRGR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 83 NLKqidRIRTQLGMVFQNFNLWSHKTVLENI-------IEAPVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGG 155
Cdd:COG3638 74 ALR---RLRRRIGMIFQQFNLVPRLSVLTNVlagrlgrTSTWRSLLGLFPPEDRERALEALERVGLADKAYQRADQLSGG 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 156 QQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGT 234
Cdd:COG3638 151 QQQRVAIARALVQEPKLILADEPVASLDPKTARQVMDLLRRIAREdGITVVVNLHQVDLARRYADRIIGLRDGRVVFDGP 230
|
....
gi 497963481 235 PEHV 238
Cdd:COG3638 231 PAEL 234
|
|
| CysA |
COG1118 |
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ... |
6-247 |
1.68e-70 |
|
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440735 [Multi-domain] Cd Length: 348 Bit Score: 220.02 E-value: 1.68e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEmkpnrkgqnrpSNLK 85
Cdd:COG1118 3 IEVRNISKRFGSFTLLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLNGRDLF-----------TNLP 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 86 QIDRirtQLGMVFQNFNLWSHKTVLENIIEAPvHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIARA 165
Cdd:COG1118 72 PRER---RVGFVFQHYALFPHMTVAENIAFGL-RVRPPSKAEIRARVEELLELVQLEGLADRYPSQLSGGQRQRVALARA 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 166 LAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVFTASQS 244
Cdd:COG1118 148 LAVEPEVLLLDEPFGALDAKVRKELRRWLRRLHDElGGTTVFVTHDQEEALELADRVVVMNQGRIEQVGTPDEVYDRPAT 227
|
....*.
gi 497963481 245 ---ARF 247
Cdd:COG1118 228 pfvARF 233
|
|
| FtsE |
COG2884 |
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning]; |
6-231 |
2.06e-70 |
|
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 215.30 E-value: 2.06e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSF-GSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAI-EMKPnrkgqnrpsn 83
Cdd:COG2884 2 IRFENVSKRYpGGREALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLsRLKR---------- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 84 lKQIDRIRTQLGMVFQNFNLWSHKTVLENIiEAPVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIA 163
Cdd:COG2884 72 -REIPYLRRRIGVVFQDFRLLPDRTVYENV-ALPLRVTGKSRKEIRRRVREVLDLVGLSDKAKALPHELSGGEQQRVAIA 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 497963481 164 RALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEE 231
Cdd:COG2884 150 RALVNRPELLLADEPTGNLDPETSWEIMELLEEINRRGTTVLIATHDLELVDRMPKRVLELEDGRLVR 217
|
|
| DppF |
COG1124 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
5-253 |
3.23e-70 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440741 [Multi-domain] Cd Length: 248 Bit Score: 215.82 E-value: 3.23e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 5 AISLRNIHKSFGSLD----VLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEMKPNRkgqnr 80
Cdd:COG1124 1 MLEVRNLSVSYGQGGrrvpVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDGRPVTRRRRK----- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 81 psnlkqidRIRTQLGMVFQN----FNlwSHKTVLEnIIEAPVHVLKRPQAEcvEHAEQLLEKVGL-ADKRHYYPAHLSGG 155
Cdd:COG1124 76 --------AFRRRVQMVFQDpyasLH--PRHTVDR-ILAEPLRIHGLPDRE--ERIAELLEQVGLpPSFLDRYPHQLSGG 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 156 QQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTL-ADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGT 234
Cdd:COG1124 143 QRQRVAIARALILEPELLLLDEPTSALDVSVQAEILNLLKDLrEERGLTYLFVSHDLAVVAHLCDRVAVMQNGRIVEELT 222
|
250
....*....|....*....
gi 497963481 235 PEHVFTASQSARFRQFIAS 253
Cdd:COG1124 223 VADLLAGPKHPYTRELLAA 241
|
|
| TauB |
COG1116 |
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ... |
1-224 |
6.76e-70 |
|
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440733 [Multi-domain] Cd Length: 260 Bit Score: 215.34 E-value: 6.76e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 1 MTT--PAISLRNIHKSF----GSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCsnL--LELPDQGEIIVGGeaiemk 72
Cdd:COG1116 1 MSAaaPALELRGVSKRFptggGGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRL--IagLEKPTSGEVLVDG------ 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 73 pnrkgqnrpsnlKQIDRIRTQLGMVFQNFNL--WshKTVLENIiEAPVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPA 150
Cdd:COG1116 73 ------------KPVTGPGPDRGVVFQEPALlpW--LTVLDNV-ALGLELRGVPKAERRERARELLELVGLAGFEDAYPH 137
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 497963481 151 HLSGGQQQRAAIARALAMEPKVMLFDEPTSALDP----ELVGEVLRVmrtLADEGMTMLVVTHEMDFAREVSNRIVFL 224
Cdd:COG1116 138 QLSGGMRQRVAIARALANDPEVLLMDEPFGALDAltreRLQDELLRL---WQETGKTVLFVTHDVDEAVFLADRVVVL 212
|
|
| 3a0107s01c2 |
TIGR00972 |
phosphate ABC transporter, ATP-binding protein; This model represents the ATP-binding protein ... |
5-252 |
7.42e-70 |
|
phosphate ABC transporter, ATP-binding protein; This model represents the ATP-binding protein of a family of ABC transporters for inorganic phosphate. In the model species Escherichia coli, a constitutive transporter for inorganic phosphate, with low affinity, is also present. The high affinity transporter that includes this polypeptide is induced when extracellular phosphate concentrations are low. The proteins most similar to the members of this family but not included appear to be amino acid transporters. [Transport and binding proteins, Anions]
Pssm-ID: 273372 [Multi-domain] Cd Length: 247 Bit Score: 214.85 E-value: 7.42e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 5 AISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLE--LPDQ---GEIIVGGEAIemkpnrkgqn 79
Cdd:TIGR00972 1 AIEIENLNLFYGEKEALKNINLDIPKNQVTALIGPSGCGKSTLLRSLNRMNdlVPGVrieGKVLFDGQDI---------- 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 80 rpsNLKQID--RIRTQLGMVFQNFNLWShKTVLENIIEAP-VHVLKrPQAECVEHAEQLLEKVGL----ADKRHYYPAHL 152
Cdd:TIGR00972 71 ---YDKKIDvvELRRRVGMVFQKPNPFP-MSIYDNIAYGPrLHGIK-DKKELDEIVEESLKKAALwdevKDRLHDSALGL 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 153 SGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEgMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQ 232
Cdd:TIGR00972 146 SGGQQQRLCIARALAVEPEVLLLDEPTSALDPIATGKIEELIQELKKK-YTIVIVTHNMQQAARISDRTAFFYDGELVEY 224
|
250 260
....*....|....*....|
gi 497963481 233 GTPEHVFTASQSARFRQFIA 252
Cdd:TIGR00972 225 GPTEQIFTNPKEKRTEDYIS 244
|
|
| ABC_Class3 |
cd03229 |
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ... |
6-228 |
2.24e-69 |
|
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 211.28 E-value: 2.24e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIemkpNRKGQNRPsnlk 85
Cdd:cd03229 1 LELKNVSKRYGQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDL----TDLEDELP---- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 86 qidRIRTQLGMVFQNFNLWSHKTVLENIIEApvhvlkrpqaecvehaeqllekvgladkrhyypahLSGGQQQRAAIARA 165
Cdd:cd03229 73 ---PLRRRIGMVFQDFALFPHLTVLENIALG-----------------------------------LSGGQQQRVALARA 114
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 497963481 166 LAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQGE 228
Cdd:cd03229 115 LAMDPDVLLLDEPTSALDPITRREVRALLKSLQAQlGITVVLVTHDLDEAARLADRVVVLRDGK 178
|
|
| CcmA |
COG1131 |
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; |
6-236 |
2.43e-68 |
|
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 210.69 E-value: 2.43e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRC-SNLLElPDQGEIIVGGEAIEmkpnrkgqnrpsnl 84
Cdd:COG1131 1 IEVRGLTKRYGDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMlLGLLR-PTSGEVRVLGEDVA-------------- 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 85 KQIDRIRTQLGMVFQNFNLWSHKTVLENI-IEAPVHVLKRPQAEcvEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIA 163
Cdd:COG1131 66 RDPAEVRRRIGYVPQEPALYPDLTVRENLrFFARLYGLPRKEAR--ERIDELLELFGLTDAADRKVGTLSGGMKQRLGLA 143
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 497963481 164 RALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPE 236
Cdd:COG1131 144 LALLHDPELLILDEPTSGLDPEARRELWELLRELAAEGKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPD 216
|
|
| ABC_Carb_Solutes_like |
cd03259 |
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ... |
6-233 |
3.62e-68 |
|
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 209.30 E-value: 3.62e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEMKPNRkgqnrpsnlk 85
Cdd:cd03259 1 LELKGLSKTYGSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDVTGVPPE---------- 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 86 qidriRTQLGMVFQNFNLWSHKTVLENIieA-PVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIAR 164
Cdd:cd03259 71 -----RRNIGMVFQDYALFPHLTVAENI--AfGLKLRGVPKAEIRARVRELLELVGLEGLLNRYPHELSGGQQQRVALAR 143
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 497963481 165 ALAMEPKVMLFDEPTSALDP----ELVGEVLRVMRTLadeGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQG 233
Cdd:cd03259 144 ALAREPSLLLLDEPLSALDAklreELREELKELQREL---GITTIYVTHDQEEALALADRIAVMNEGRIVQVG 213
|
|
| ABC_PstB_phosphate_transporter |
cd03260 |
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ... |
6-238 |
7.15e-66 |
|
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).
Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 203.95 E-value: 7.15e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLL-----ELPDQGEIIVGGEAIemkpnRKGQNR 80
Cdd:cd03260 1 IELRDLNVYYGDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLndlipGAPDEGEVLLDGKDI-----YDLDVD 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 81 PSNLkqidriRTQLGMVFQNFNLWsHKTVLENIIEAPVHVLKRPQAECVEHAEQLLEKVGLAD--KRHYYPAHLSGGQQQ 158
Cdd:cd03260 76 VLEL------RRRVGMVFQKPNPF-PGSIYDNVAYGLRLHGIKLKEELDERVEEALRKAALWDevKDRLHALGLSGGQQQ 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 159 RAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEgMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHV 238
Cdd:cd03260 149 RLCLARALANEPEVLLLDEPTSALDPISTAKIEELIAELKKE-YTIVIVTHNMQQAARVADRTAFLLNGRLVEFGPTEQI 227
|
|
| ABC_PhnC_transporter |
cd03256 |
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ... |
6-236 |
2.08e-65 |
|
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 203.57 E-value: 2.08e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLD-VLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIemkpnrkGQNRPSNL 84
Cdd:cd03256 1 IEVENLSKTYPNGKkALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDI-------NKLKGKAL 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 85 KQIdriRTQLGMVFQNFNLWSHKTVLENIIEA--PVH-----VLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQ 157
Cdd:cd03256 74 RQL---RRQIGMIFQQFNLIERLSVLENVLSGrlGRRstwrsLFGLFPKEEKQRALAALERVGLLDKAYQRADQLSGGQQ 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 158 QRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPE 236
Cdd:cd03256 151 QRVAIARALMQQPKLILADEPVASLDPASSRQVMDLLKRINREeGITVIVSLHQVDLAREYADRIVGLKDGRIVFDGPPA 230
|
|
| ABC_cobalt_CbiO_domain1 |
cd03225 |
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ... |
7-228 |
2.81e-65 |
|
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 201.93 E-value: 2.81e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 7 SLRNIHKSFGSLD--VLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIemkpnrkgqnRPSNL 84
Cdd:cd03225 1 ELKNLSFSYPDGArpALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDL----------TKLSL 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 85 KQIdriRTQLGMVFQN-----FNLwshkTVLENIIEAPVHvLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQR 159
Cdd:cd03225 71 KEL---RRKVGLVFQNpddqfFGP----TVEEEVAFGLEN-LGLPEEEIEERVEEALELVGLEGLRDRSPFTLSGGQKQR 142
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 497963481 160 AAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGE 228
Cdd:cd03225 143 VAIAGVLAMDPDILLLDEPTAGLDPAGRRELLELLKKLKAEGKTIIIVTHDLDLLLELADRVIVLEDGK 211
|
|
| MalK |
COG3839 |
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ... |
5-239 |
3.61e-65 |
|
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];
Pssm-ID: 443050 [Multi-domain] Cd Length: 352 Bit Score: 206.46 E-value: 3.61e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 5 AISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAI-EMKPNRKGqnrpsn 83
Cdd:COG3839 3 SLELENVSKSYGGVEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIGGRDVtDLPPKDRN------ 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 84 lkqidrirtqLGMVFQNFNLWSHKTVLENIiEAPVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIA 163
Cdd:COG3839 77 ----------IAMVFQSYALYPHMTVYENI-AFPLKLRKVPKAEIDRRVREAAELLGLEDLLDRKPKQLSGGQRQRVALG 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 164 RALAMEPKVMLFDEPTSALDPElvgevLRV-MRT-----LADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEH 237
Cdd:COG3839 146 RALVREPKVFLLDEPLSNLDAK-----LRVeMRAeikrlHRRLGTTTIYVTHDQVEAMTLADRIAVMNDGRIQQVGTPEE 220
|
..
gi 497963481 238 VF 239
Cdd:COG3839 221 LY 222
|
|
| ABC_NikE_OppD_transporters |
cd03257 |
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ... |
6-233 |
1.03e-64 |
|
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.
Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 201.20 E-value: 1.03e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSF----GSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEMKPNRKGQNRp 81
Cdd:cd03257 2 LEVKNLSVSFptggGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKLSRRLRKIR- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 82 snlkqidriRTQLGMVFQN----FNlwSHKTVLENIIEAP-VHVLKRPQAECVEHAEQLLEKVGLADKR-HYYPAHLSGG 155
Cdd:cd03257 81 ---------RKEIQMVFQDpmssLN--PRMTIGEQIAEPLrIHGKLSKKEARKEAVLLLLVGVGLPEEVlNRYPHELSGG 149
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 497963481 156 QQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQG 233
Cdd:cd03257 150 QRQRVAIARALALNPKLLIADEPTSALDVSVQAQILDLLKKLQEElGLTLLFITHDLGVVAKIADRVAVMYAGKIVEEG 228
|
|
| ABC_Mj1267_LivG_branched |
cd03219 |
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ... |
6-238 |
4.45e-64 |
|
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).
Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 199.97 E-value: 4.45e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRC-SNLLElPDQGEIIVGGEAIE-MKPNRkgqnrpsn 83
Cdd:cd03219 1 LEVRGLTKRFGGLVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLiSGFLR-PTSGSVLFDGEDITgLPPHE-------- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 84 lkqidriRTQLGMV--FQNFNLWSHKTVLENIIEAPVHVLKRP---------QAECVEHAEQLLEKVGLADKRHYYPAHL 152
Cdd:cd03219 72 -------IARLGIGrtFQIPRLFPELTVLENVMVAAQARTGSGlllararreEREARERAEELLERVGLADLADRPAGEL 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 153 SGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQ 232
Cdd:cd03219 145 SYGQQRRLEIARALATDPKLLLLDEPAAGLNPEETEELAELIRELRERGITVLLVEHDMDVVMSLADRVTVLDQGRVIAE 224
|
....*.
gi 497963481 233 GTPEHV 238
Cdd:cd03219 225 GTPDEV 230
|
|
| ABC_PotA_N |
cd03300 |
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ... |
6-251 |
3.50e-63 |
|
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 197.46 E-value: 3.50e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIemkpnrkgQNRPSNLK 85
Cdd:cd03300 1 IELENVSKFYGGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDI--------TNLPPHKR 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 86 QIdrirtqlGMVFQNFNLWSHKTVLENIiEAPVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIARA 165
Cdd:cd03300 73 PV-------NTVFQNYALFPHLTVFENI-AFGLRLKKLPKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARA 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 166 LAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVFTASQS 244
Cdd:cd03300 145 LVNEPKVLLLDEPLGALDLKLRKDMQLELKRLQKElGITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGTPEEIYEEPAN 224
|
....*..
gi 497963481 245 ARFRQFI 251
Cdd:cd03300 225 RFVADFI 231
|
|
| ABC_CysA_sulfate_importer |
cd03296 |
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ... |
5-253 |
1.05e-62 |
|
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 196.41 E-value: 1.05e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 5 AISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEMKPNRkgqnrpsnl 84
Cdd:cd03296 2 SIEVRNVSKRFGDFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDATDVPVQ--------- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 85 kqiDRirtQLGMVFQNFNLWSHKTVLENI---IEAPVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAA 161
Cdd:cd03296 73 ---ER---NVGFVFQHYALFRHMTVFDNVafgLRVKPRSERPPEAEIRAKVHELLKLVQLDWLADRYPAQLSGGQRQRVA 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 162 IARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVFT 240
Cdd:cd03296 147 LARALAVEPKVLLLDEPFGALDAKVRKELRRWLRRLHDElHVTTVFVTHDQEEALEVADRVVVMNKGRIEQVGTPDEVYD 226
|
250
....*....|...
gi 497963481 241 ASQSARFRQFIAS 253
Cdd:cd03296 227 HPASPFVYSFLGE 239
|
|
| ABC_NrtD_SsuB_transporters |
cd03293 |
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ... |
6-224 |
3.55e-62 |
|
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 194.23 E-value: 3.55e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLD----VLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIemkpnrkgqNRP 81
Cdd:cd03293 1 LEVRNVSKTYGGGGgavtALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGEPV---------TGP 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 82 SNlkqidrirtQLGMVFQNFNLWSHKTVLENIiEAPVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAA 161
Cdd:cd03293 72 GP---------DRGYVFQQDALLPWLTVLDNV-ALGLELQGVPKAEARERAEELLELVGLSGFENAYPHQLSGGMRQRVA 141
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 497963481 162 IARALAMEPKVMLFDEPTSALDP---ELVGEVLrvMRTLADEGMTMLVVTHEMDFAREVSNRIVFL 224
Cdd:cd03293 142 LARALAVDPDVLLLDEPFSALDAltrEQLQEEL--LDIWRETGKTVLLVTHDIDEAVFLADRVVVL 205
|
|
| LivG |
COG0411 |
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ... |
2-238 |
6.29e-62 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];
Pssm-ID: 440180 [Multi-domain] Cd Length: 257 Bit Score: 194.87 E-value: 6.29e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 2 TTPAISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRC-SNLLElPDQGEIIVGGEAIE-MKPNRkgqn 79
Cdd:COG0411 1 SDPLLEVRGLTKRFGGLVAVDDVSLEVERGEIVGLIGPNGAGKTTLFNLiTGFYR-PTSGRILFDGRDITgLPPHR---- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 80 rpsnlkqidriRTQLGMV--FQNFNLWSHKTVLENIIEAPVHVLK--------------RPQAECVEHAEQLLEKVGLAD 143
Cdd:COG0411 76 -----------IARLGIArtFQNPRLFPELTVLENVLVAAHARLGrgllaallrlprarREEREARERAEELLERVGLAD 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 144 KRHYYPAHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIV 222
Cdd:COG0411 145 RADEPAGNLSYGQQRRLEIARALATEPKLLLLDEPAAGLNPEETEELAELIRRLRDErGITILLIEHDMDLVMGLADRIV 224
|
250
....*....|....*.
gi 497963481 223 FLHQGEIEEQGTPEHV 238
Cdd:COG0411 225 VLDFGRVIAEGTPAEV 240
|
|
| ECF_ATPase_1 |
TIGR04520 |
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ... |
6-240 |
7.82e-62 |
|
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 275313 [Multi-domain] Cd Length: 268 Bit Score: 194.96 E-value: 7.82e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSF--GSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGeaiemkpnrkgqNRPSN 83
Cdd:TIGR04520 1 IEVENVSFSYpeSEKPALKNVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGLLLPTSGKVTVDG------------LDTLD 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 84 LKQIDRIRTQLGMVFQN-FNLWSHKTV-------LENiieapvhvLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGG 155
Cdd:TIGR04520 69 EENLWEIRKKVGMVFQNpDNQFVGATVeddvafgLEN--------LGVPREEMRKRVDEALKLVGMEDFRDREPHLLSGG 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 156 QQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTL-ADEGMTMLVVTHEMDFAREvSNRIVFLHQGEIEEQGT 234
Cdd:TIGR04520 141 QKQRVAIAGVLAMRPDIIILDEATSMLDPKGRKEVLETIRKLnKEEGITVISITHDMEEAVL-ADRVIVMNKGKIVAEGT 219
|
....*.
gi 497963481 235 PEHVFT 240
Cdd:TIGR04520 220 PREIFS 225
|
|
| ABC_OpuCA_Osmoprotection |
cd03295 |
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ... |
6-251 |
2.29e-60 |
|
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 190.59 E-value: 2.29e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLD-VLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIemkpnrkgqnrpsnl 84
Cdd:cd03295 1 IEFENVTKRYGGGKkAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEDI--------------- 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 85 KQID--RIRTQLGMVFQNFNLWSHKTVLENIIEAPvHVLKRPQAECVEHAEQLLEKVGLADK--RHYYPAHLSGGQQQRA 160
Cdd:cd03295 66 REQDpvELRRKIGYVIQQIGLFPHMTVEENIALVP-KLLKWPKEKIRERADELLALVGLDPAefADRYPHELSGGQQQRV 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 161 AIARALAMEPKVMLFDEPTSALDP----ELVGEVLRVMRTLadeGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPE 236
Cdd:cd03295 145 GVARALAADPPLLLMDEPFGALDPitrdQLQEEFKRLQQEL---GKTIVFVTHDIDEAFRLADRIAIMKNGEIVQVGTPD 221
|
250
....*....|....*
gi 497963481 237 HVFTASQSARFRQFI 251
Cdd:cd03295 222 EILRSPANDFVAEFV 236
|
|
| ABC_phnC |
TIGR02315 |
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ... |
6-238 |
3.53e-60 |
|
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]
Pssm-ID: 131368 [Multi-domain] Cd Length: 243 Bit Score: 190.20 E-value: 3.53e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLD-VLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIemkpnrkGQNRPSNL 84
Cdd:TIGR02315 2 LEVENLSKVYPNGKqALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLVEPSSGSILLEGTDI-------TKLRGKKL 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 85 KQIdriRTQLGMVFQNFNLWSHKTVLENIIEAPV-------HVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQ 157
Cdd:TIGR02315 75 RKL---RRRIGMIFQHYNLIERLTVLENVLHGRLgykptwrSLLGRFSEEDKERALSALERVGLADKAYQRADQLSGGQQ 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 158 QRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPE 236
Cdd:TIGR02315 152 QRVAIARALAQQPDLILADEPIASLDPKTSKQVMDYLKRINKEdGITVIINLHQVDLAKKYADRIVGLKAGEIVFDGAPS 231
|
..
gi 497963481 237 HV 238
Cdd:TIGR02315 232 EL 233
|
|
| NatA |
COG4555 |
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ... |
6-238 |
8.55e-60 |
|
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 189.30 E-value: 8.55e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEmkpnrkgqnrpsnlK 85
Cdd:COG4555 2 IEVENLSKKYGKVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGEDVR--------------K 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 86 QIDRIRTQLGMVFQNFNLWSHKTVLENI-IEAPVHVLKRPQAECVehAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIAR 164
Cdd:COG4555 68 EPREARRQIGVLPDERGLYDRLTVRENIrYFAELYGLFDEELKKR--IEELIELLGLEEFLDRRVGELSTGMKKKVALAR 145
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 497963481 165 ALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHV 238
Cdd:COG4555 146 ALVHDPKVLLLDEPTNGLDVMARRLLREILRALKKEGKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGSLDEL 219
|
|
| ABC_Pro_Gly_Betaine |
cd03294 |
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ... |
11-251 |
1.13e-59 |
|
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213261 [Multi-domain] Cd Length: 269 Bit Score: 189.78 E-value: 1.13e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 11 IHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEmKPNRKgqnrpsNLKQIDRI 90
Cdd:cd03294 30 ILKKTGQTVGVNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQDIA-AMSRK------ELRELRRK 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 91 RtqLGMVFQNFNLWSHKTVLENIiEAPVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIARALAMEP 170
Cdd:cd03294 103 K--ISMVFQSFALLPHRTVLENV-AFGLEVQGVPRAEREERAAEALELVGLEGWEHKYPDELSGGMQQRVGLARALAVDP 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 171 KVMLFDEPTSALDP----ELVGEVLRVMrtlADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVFTASQSAR 246
Cdd:cd03294 180 DILLMDEAFSALDPlirrEMQDELLRLQ---AELQKTIVFITHDLDEALRLGDRIAIMKDGRLVQVGTPEEILTNPANDY 256
|
....*
gi 497963481 247 FRQFI 251
Cdd:cd03294 257 VREFF 261
|
|
| PstB |
COG1117 |
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
2-251 |
1.14e-59 |
|
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440734 [Multi-domain] Cd Length: 258 Bit Score: 189.09 E-value: 1.14e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 2 TTPAISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSN-LLEL-PDQ---GEIIVGGEAIemkpnrk 76
Cdd:COG1117 8 LEPKIEVRNLNVYYGDKQALKDINLDIPENKVTALIGPSGCGKSTLLRCLNrMNDLiPGArveGEILLDGEDI------- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 77 gqnrpsNLKQID--RIRTQLGMVFQNFNLWShKTVLENIIEAPVHVLKRPQAECVEHAEQLLEKVGL----ADKRHYYPA 150
Cdd:COG1117 81 ------YDPDVDvvELRRRVGMVFQKPNPFP-KSIYDNVAYGLRLHGIKSKSELDEIVEESLRKAALwdevKDRLKKSAL 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 151 HLSGGQQQRAAIARALAMEPKVMLFDEPTSALDP-------ELvgevlrvMRTLADEgMTMLVVTHEMDFAREVSNRIVF 223
Cdd:COG1117 154 GLSGGQQQRLCIARALAVEPEVLLMDEPTSALDPistakieEL-------ILELKKD-YTIVIVTHNMQQAARVSDYTAF 225
|
250 260
....*....|....*....|....*...
gi 497963481 224 LHQGEIEEQGTPEHVFTASQSARFRQFI 251
Cdd:COG1117 226 FYLGELVEFGPTEQIFTNPKDKRTEDYI 253
|
|
| FepC |
COG1120 |
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ... |
5-241 |
3.43e-59 |
|
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];
Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 187.94 E-value: 3.43e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 5 AISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRC-SNLLElPDQGEIIVGGEAIemkpnrkgqnrpSN 83
Cdd:COG1120 1 MLEAENLSVGYGGRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRAlAGLLK-PSSGEVLLDGRDL------------AS 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 84 LKQIDRIRtQLGMVFQNFNLWSHKTVLEnIIE---AP-VHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQR 159
Cdd:COG1120 68 LSRRELAR-RIAYVPQEPPAPFGLTVRE-LVAlgrYPhLGLFGRPSAEDREAVEEALERTGLEHLADRPVDELSGGERQR 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 160 AAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHV 238
Cdd:COG1120 146 VLIARALAQEPPLLLLDEPTSHLDLAHQLEVLELLRRLARErGRTVVMVLHDLNLAARYADRLVLLKDGRIVAQGPPEEV 225
|
...
gi 497963481 239 FTA 241
Cdd:COG1120 226 LTP 228
|
|
| PhnT2 |
TIGR03265 |
putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ... |
4-253 |
2.70e-58 |
|
putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ATP-binding protein is found in a number of genomes in operon-like contexts strongly suggesting a substrate specificity for 2-aminoethylphosphonate (2-AEP). The characterized PhnSTUV system is absent in the genomes in which this system is found. These genomes encode systems for the catabolism of 2-AEP, making the need for a 2-AEP-specific transporter likely. [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 274496 [Multi-domain] Cd Length: 353 Bit Score: 188.71 E-value: 2.70e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 4 PAISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIemkpnrkgqnrpSN 83
Cdd:TIGR03265 3 PYLSIDNIRKRFGAFTALKDISLSVKKGEFVCLLGPSGCGKTTLLRIIAGLERQTAGTIYQGGRDI------------TR 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 84 LKQIDRirtQLGMVFQNFNLWSHKTVLENIiEAPVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIA 163
Cdd:TIGR03265 71 LPPQKR---DYGIVFQSYALFPNLTVADNI-AYGLKNRGMGRAEVAERVAELLDLVGLPGSERKYPGQLSGGQQQRVALA 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 164 RALAMEPKVMLFDEPTSALDPE----LVGEVLRVMRTLadeGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVF 239
Cdd:TIGR03265 147 RALATSPGLLLLDEPLSALDARvrehLRTEIRQLQRRL---GVTTIMVTHDQEEALSMADRIVVMNHGVIEQVGTPQEIY 223
|
250
....*....|....
gi 497963481 240 TASQSARFRQFIAS 253
Cdd:TIGR03265 224 RHPATPFVADFVGE 237
|
|
| OpuBA |
COG1125 |
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ... |
6-251 |
3.55e-58 |
|
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440742 [Multi-domain] Cd Length: 306 Bit Score: 186.83 E-value: 3.55e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLDV-LKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAI-EMKPnrkgqnrpsn 83
Cdd:COG1125 2 IEFENVTKRYPDGTVaVDDLSLTIPAGEFTVLVGPSGCGKTTTLRMINRLIEPTSGRILIDGEDIrDLDP---------- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 84 lkqiDRIRTQLGMVFQNFNLWSHKTVLENIIEAPvHVLKRPQAECVEHAEQLLEKVGL--ADKRHYYPAHLSGGQQQRAA 161
Cdd:COG1125 72 ----VELRRRIGYVIQQIGLFPHMTVAENIATVP-RLLGWDKERIRARVDELLELVGLdpEEYRDRYPHELSGGQQQRVG 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 162 IARALAMEPKVMLFDEPTSALDP----ELVGEVLRVMRTLadeGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEH 237
Cdd:COG1125 147 VARALAADPPILLMDEPFGALDPitreQLQDELLRLQREL---GKTIVFVTHDIDEALKLGDRIAVMREGRIVQYDTPEE 223
|
250
....*....|....
gi 497963481 238 VFTASQSARFRQFI 251
Cdd:COG1125 224 ILANPANDFVADFV 237
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
3-244 |
6.87e-58 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 192.04 E-value: 6.87e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 3 TPAISLRNIHKSF--GSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLeLPD----QGEIIVGGEAIemkpnrk 76
Cdd:COG1123 2 TPLLEVRDLSVRYpgGDVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGL-LPHggriSGEVLLDGRDL------- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 77 gqnrpsnLKQIDRIR-TQLGMVFQN----FNLWshkTVLENIIEAPVhVLKRPQAECVEHAEQLLEKVGLADKRHYYPAH 151
Cdd:COG1123 74 -------LELSEALRgRRIGMVFQDpmtqLNPV---TVGDQIAEALE-NLGLSRAEARARVLELLEAVGLERRLDRYPHQ 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 152 LSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQGEIE 230
Cdd:COG1123 143 LSGGQRQRVAIAMALALDPDLLIADEPTTALDVTTQAEILDLLRELQRErGTTVLLITHDLGVVAEIADRVVVMDDGRIV 222
|
250
....*....|....
gi 497963481 231 EQGTPEHVFTASQS 244
Cdd:COG1123 223 EDGPPEEILAAPQA 236
|
|
| YbbA |
COG4181 |
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ... |
1-236 |
2.64e-57 |
|
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443338 [Multi-domain] Cd Length: 233 Bit Score: 182.25 E-value: 2.64e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 1 MTTPAISLRNIHKSF----GSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEaiemkpnrk 76
Cdd:COG4181 4 SSAPIIELRGLTKTVgtgaGELTILKGISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTVRLAGQ--------- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 77 gqnrpsNLKQID-----RIRTQ-LGMVFQNFNLWSHKTVLENIIeAPVHVLKRPQAEcvEHAEQLLEKVGLADKRHYYPA 150
Cdd:COG4181 75 ------DLFALDedaraRLRARhVGFVFQSFQLLPTLTALENVM-LPLELAGRRDAR--ARARALLERVGLGHRLDHYPA 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 151 HLSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREvSNRIVFLHQGEI 229
Cdd:COG4181 146 QLSGGEQQRVALARAFATEPAILFADEPTGNLDAATGEQIIDLLFELNRErGTTLVLVTHDPALAAR-CDRVLRLRAGRL 224
|
....*..
gi 497963481 230 EEQGTPE 236
Cdd:COG4181 225 VEDTAAT 231
|
|
| ZnuC |
COG1121 |
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
1-241 |
7.63e-56 |
|
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 179.13 E-value: 7.63e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 1 MTTPAISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCsnLLEL--PDQGEIIVGGEAIEMKPNRKG- 77
Cdd:COG1121 2 MMMPAIELENLTVSYGGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKA--ILGLlpPTSGTVRLFGKPPRRARRRIGy 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 78 --QNRpsnlkQIDRirtqlgmvfqNFNLwshkTVLEnIIE----APVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAH 151
Cdd:COG1121 80 vpQRA-----EVDW----------DFPI----TVRD-VVLmgryGRRGLFRRPSRADREAVDEALERVGLEDLADRPIGE 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 152 LSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEE 231
Cdd:COG1121 140 LSGGQQQRVLLARALAQDPDLLLLDEPFAGVDAATEEALYELLRELRREGKTILVVTHDLGAVREYFDRVLLLNRGLVAH 219
|
250
....*....|
gi 497963481 232 qGTPEHVFTA 241
Cdd:COG1121 220 -GPPEEVLTP 228
|
|
| ProV |
COG4175 |
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ... |
3-236 |
8.77e-56 |
|
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443334 [Multi-domain] Cd Length: 389 Bit Score: 183.38 E-value: 8.77e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 3 TPAISLRNIHKSFGS-----LDVLK-------------------GISIEANQGEVISILGSSGSGKSTLLRCSNLLELPD 58
Cdd:COG4175 1 MPKIEVRNLYKIFGKrperaLKLLDqgkskdeilektgqtvgvnDASFDVEEGEIFVIMGLSGSGKSTLVRCLNRLIEPT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 59 QGEIIVGGEAIeMKPNRKGqnrpsnLKQIdRiRTQLGMVFQNFNLWSHKTVLENIiEAPVHVLKRPQAECVEHAEQLLEK 138
Cdd:COG4175 81 AGEVLIDGEDI-TKLSKKE------LREL-R-RKKMSMVFQHFALLPHRTVLENV-AFGLEIQGVPKAERRERAREALEL 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 139 VGLADKRHYYPAHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDP----ELVGEVLRVMRTLadeGMTMLVVTHEMDFA 214
Cdd:COG4175 151 VGLAGWEDSYPDELSGGMQQRVGLARALATDPDILLMDEAFSALDPlirrEMQDELLELQAKL---KKTIVFITHDLDEA 227
|
250 260
....*....|....*....|..
gi 497963481 215 REVSNRIVFLHQGEIEEQGTPE 236
Cdd:COG4175 228 LRLGDRIAIMKDGRIVQIGTPE 249
|
|
| FtsE |
TIGR02673 |
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC ... |
6-228 |
8.53e-55 |
|
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC transporter ATP-binding protein family. This protein, and its permease partner FtsX, localize to the division site. In a number of species, the ftsEX gene pair is located next to FtsY, the signal recognition particle-docking protein. [Cellular processes, Cell division]
Pssm-ID: 131721 [Multi-domain] Cd Length: 214 Bit Score: 175.51 E-value: 8.53e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSF-GSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEMKPNRkgqnrpsnl 84
Cdd:TIGR02673 2 IEFHNVSKAYpGGVAALHDVSLHIRKGEFLFLTGPSGAGKTTLLKLLYGALTPSRGQVRIAGEDVNRLRGR--------- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 85 kQIDRIRTQLGMVFQNFNLWSHKTVLENIiEAPVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIAR 164
Cdd:TIGR02673 73 -QLPLLRRRIGVVFQDFRLLPDRTVYENV-ALPLEVRGKKEREIQRRVGAALRQVGLEHKADAFPEQLSGGEQQRVAIAR 150
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 497963481 165 ALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGE 228
Cdd:TIGR02673 151 AIVNSPPLLLADEPTGNLDPDLSERILDLLKRLNKRGTTVIVATHDLSLVDRVAHRVIILDDGR 214
|
|
| FetA |
COG4619 |
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism]; |
6-229 |
9.30e-55 |
|
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443661 [Multi-domain] Cd Length: 209 Bit Score: 175.00 E-value: 9.30e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAI-EMKPnrkgqnrpsnl 84
Cdd:COG4619 1 LELEGLSFRVGGKPILSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKPLsAMPP----------- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 85 kqiDRIRTQLGMVFQNFNLWsHKTVLENIIEAPVHVLKRPQAEcveHAEQLLEKVGLA----DKRhyyPAHLSGGQQQRA 160
Cdd:COG4619 70 ---PEWRRQVAYVPQEPALW-GGTVRDNLPFPFQLRERKFDRE---RALELLERLGLPpdilDKP---VERLSGGERQRL 139
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 161 AIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTL-ADEGMTMLVVTHEMDFAREVSNRIVFLHQGEI 229
Cdd:COG4619 140 ALIRALLLQPDVLLLDEPTSALDPENTRRVEELLREYlAEEGRAVLWVSHDPEQIERVADRVLTLEAGRL 209
|
|
| PRK10851 |
PRK10851 |
sulfate/thiosulfate ABC transporter ATP-binding protein CysA; |
5-247 |
2.89e-54 |
|
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 178.35 E-value: 2.89e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 5 AISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIemkpnrkgqnrpSNL 84
Cdd:PRK10851 2 SIEIANIKKSFGRTQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDV------------SRL 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 85 KQIDRirtQLGMVFQNFNLWSHKTVLENIIEApVHVL---KRPQAECVEH-AEQLLEKVGLADKRHYYPAHLSGGQQQRA 160
Cdd:PRK10851 70 HARDR---KVGFVFQHYALFRHMTVFDNIAFG-LTVLprrERPNAAAIKAkVTQLLEMVQLAHLADRYPAQLSGGQKQRV 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 161 AIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVF 239
Cdd:PRK10851 146 ALARALAVEPQILLLDEPFGALDAQVRKELRRWLRQLHEElKFTSVFVTHDQEEAMEVADRVVVMSQGNIEQAGTPDQVW 225
|
....*...
gi 497963481 240 TASQSaRF 247
Cdd:PRK10851 226 REPAT-RF 232
|
|
| ABC_DR_subfamily_A |
cd03230 |
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ... |
6-229 |
4.45e-54 |
|
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 172.20 E-value: 4.45e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRC-SNLLElPDQGEIIVGGEAIEmkpnrkgqnrpsnl 84
Cdd:cd03230 1 IEVRNLSKRYGKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIiLGLLK-PDSGEIKVLGKDIK-------------- 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 85 KQIDRIRTQLGMVFQNFNLWSHKTVLENIieapvhvlkrpqaecvehaeqllekvgladkrhyypaHLSGGQQQRAAIAR 164
Cdd:cd03230 66 KEPEEVKRRIGYLPEEPSLYENLTVRENL-------------------------------------KLSGGMKQRLALAQ 108
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 497963481 165 ALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEI 229
Cdd:cd03230 109 ALLHDPELLILDEPTSGLDPESRREFWELLRELKKEGKTILLSSHILEEAERLCDRVAILNNGRI 173
|
|
| ThiQ |
COG3840 |
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism]; |
6-251 |
8.66e-54 |
|
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 173.40 E-value: 8.66e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLdvLKGISIEANQGEVISILGSSGSGKSTLLrcsNLL---ELPDQGEIIVGGEAIEMKPNRKgqnRPs 82
Cdd:COG3840 2 LRLDDLTYRYGDF--PLRFDLTIAAGERVAILGPSGAGKSTLL---NLIagfLPPDSGRILWNGQDLTALPPAE---RP- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 83 nlkqidrirtqLGMVFQNFNLWSHKTVLENI---IEAPVHvLKRPQAECVEHAeqlLEKVGLADKRHYYPAHLSGGQQQR 159
Cdd:COG3840 73 -----------VSMLFQENNLFPHLTVAQNIglgLRPGLK-LTAEQRAQVEQA---LERVGLAGLLDRLPGQLSGGQRQR 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 160 AAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHV 238
Cdd:COG3840 138 VALARCLVRKRPILLLDEPFSALDPALRQEMLDLVDELCRErGLTVLMVTHDPEDAARIADRVLLVADGRIAADGPTAAL 217
|
250
....*....|...
gi 497963481 239 FTASQSARFRQFI 251
Cdd:COG3840 218 LDGEPPPALAAYL 230
|
|
| L_ocin_972_ABC |
TIGR03608 |
putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly ... |
8-224 |
9.14e-54 |
|
putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly wide distribution consists of a polypeptide related to the lactococcin 972 (see TIGR01653) and multiple-membrane-spanning putative immunity protein (see TIGR01654). This model represents a small clade within the ABC transporters that regularly are found adjacent to these bacteriocin system gene pairs and are likely serve as export proteins. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 188353 [Multi-domain] Cd Length: 206 Bit Score: 172.41 E-value: 9.14e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 8 LRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEaiemkpnrkgQNRPSNLKQI 87
Cdd:TIGR03608 1 LKNISKKFGDKVILDDLNLTIEKGKMYAIIGESGSGKSTLLNIIGLLEKFDSGQVYLNGQ----------ETPPLNSKKA 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 88 DRI-RTQLGMVFQNFNLWSHKTVLENIIEAPVHVlKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIARAL 166
Cdd:TIGR03608 71 SKFrREKLGYLFQNFALIENETVEENLDLGLKYK-KLSKKEKREKKKEALEKVGLNLKLKQKIYELSGGEQQRVALARAI 149
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 497963481 167 AMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFArEVSNRIVFL 224
Cdd:TIGR03608 150 LKPPPLILADEPTGSLDPKNRDEVLDLLLELNDEGKTIIIVTHDPEVA-KQADRVIEL 206
|
|
| ECF_ATPase_2 |
TIGR04521 |
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ... |
6-240 |
1.55e-53 |
|
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 275314 [Multi-domain] Cd Length: 277 Bit Score: 174.18 E-value: 1.55e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFG-----SLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIemkpnrkgqnR 80
Cdd:TIGR04521 1 IKLKNVSYIYQpgtpfEKKALDDVSLTIEDGEFVAIIGHTGSGKSTLIQHLNGLLKPTSGTVTIDGRDI----------T 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 81 PSNLKQIDRIRTQLGMVFQN-----FnlwsHKTVLENIIEAPVHvLKRPQAECVEHAEQLLEKVGLADKrhYY---PAHL 152
Cdd:TIGR04521 71 AKKKKKLKDLRKKVGLVFQFpehqlF----EETVYKDIAFGPKN-LGLSEEEAEERVKEALELVGLDEE--YLersPFEL 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 153 SGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQGEIEE 231
Cdd:TIGR04521 144 SGGQMRRVAIAGVLAMEPEVLILDEPTAGLDPKGRKEILDLFKRLHKEkGLTVILVTHSMEDVAEYADRVIVMHKGKIVL 223
|
....*....
gi 497963481 232 QGTPEHVFT 240
Cdd:TIGR04521 224 DGTPREVFS 232
|
|
| DppD |
COG0444 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
6-241 |
4.95e-53 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 174.09 E-value: 4.95e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSF----GSLDVLKGISIEANQGEVISILGSSGSGKSTLLRC-SNLLELP--DQGEIIVGGEAI-EMKPnrkg 77
Cdd:COG0444 2 LEVRNLKVYFptrrGVVKAVDGVSFDVRRGETLGLVGESGSGKSTLARAiLGLLPPPgiTSGEILFDGEDLlKLSE---- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 78 qnrpsnlKQIDRIR-TQLGMVFQN----FN-LWshkTVLENIIEAPVHVLKRPQAECVEHAEQLLEKVGLADKRHY---Y 148
Cdd:COG0444 78 -------KELRKIRgREIQMIFQDpmtsLNpVM---TVGDQIAEPLRIHGGLSKAEARERAIELLERVGLPDPERRldrY 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 149 PAHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQG 227
Cdd:COG0444 148 PHELSGGMRQRVMIARALALEPKLLIADEPTTALDVTIQAQILNLLKDLQRElGLAILFITHDLGVVAEIADRVAVMYAG 227
|
250
....*....|....
gi 497963481 228 EIEEQGTPEHVFTA 241
Cdd:COG0444 228 RIVEEGPVEELFEN 241
|
|
| potA |
PRK09452 |
spermidine/putrescine ABC transporter ATP-binding protein PotA; |
1-239 |
6.83e-53 |
|
spermidine/putrescine ABC transporter ATP-binding protein PotA;
Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 175.52 E-value: 6.83e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 1 MTTPAISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEMKPnrkGQNR 80
Cdd:PRK09452 10 SLSPLVELRGISKSFDGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDITHVP---AENR 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 81 PSNlkqidrirtqlgMVFQNFNLWSHKTVLENIIEApVHVLKRPQAECVEHAEQLLEKV---GLADKRhyyPAHLSGGQQ 157
Cdd:PRK09452 87 HVN------------TVFQSYALFPHMTVFENVAFG-LRMQKTPAAEITPRVMEALRMVqleEFAQRK---PHQLSGGQQ 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 158 QRAAIARALAMEPKVMLFDEPTSALD----PELVGEVLRVMRTLadeGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQG 233
Cdd:PRK09452 151 QRVAIARAVVNKPKVLLLDESLSALDyklrKQMQNELKALQRKL---GITFVFVTHDQEEALTMSDRIVVMRDGRIEQDG 227
|
....*.
gi 497963481 234 TPEHVF 239
Cdd:PRK09452 228 TPREIY 233
|
|
| ABC_MalK_N |
cd03301 |
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ... |
6-233 |
2.09e-52 |
|
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.
Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 169.36 E-value: 2.09e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEaiemkpnrkgqnRPSNLK 85
Cdd:cd03301 1 VELENVTKRFGNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGR------------DVTDLP 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 86 QIDRirtQLGMVFQNFNLWSHKTVLENIiEAPVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIARA 165
Cdd:cd03301 69 PKDR---DIAMVFQNYALYPHMTVYDNI-AFGLKLRKVPKDEIDERVREVAELLQIEHLLDRKPKQLSGGQRQRVALGRA 144
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 497963481 166 LAMEPKVMLFDEPTSALDP----ELVGEVLRVMRTLadeGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQG 233
Cdd:cd03301 145 IVREPKVFLMDEPLSNLDAklrvQMRAELKRLQQRL---GTTTIYVTHDQVEAMTMADRIAVMNDGQIQQIG 213
|
|
| ABC_TM1139_LivF_branched |
cd03224 |
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ... |
6-236 |
5.26e-52 |
|
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.
Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 168.38 E-value: 5.26e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRC-SNLLElPDQGEIIVGGEAIemkpnrkgqnrpSNL 84
Cdd:cd03224 1 LEVENLNAGYGKSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTiMGLLP-PRSGSIRFDGRDI------------TGL 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 85 KQIDRIRTQLGMVFQNFNLWSHKTVLENIIEAPVHVLKRPQAECVEHAEQLLEKvgLADKRHYYPAHLSGGQQQRAAIAR 164
Cdd:cd03224 68 PPHERARAGIGYVPEGRRIFPELTVEENLLLGAYARRRAKRKARLERVYELFPR--LKERRKQLAGTLSGGEQQMLAIAR 145
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 497963481 165 ALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPE 236
Cdd:cd03224 146 ALMSRPKLLLLDEPSEGLAPKIVEEIFEAIRELRDEGVTILLVEQNARFALEIADRAYVLERGRVVLEGTAA 217
|
|
| cbiO |
PRK13635 |
energy-coupling factor ABC transporter ATP-binding protein; |
1-243 |
6.14e-51 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 167.50 E-value: 6.14e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 1 MTTPAISLRNIHKSFGSLD--VLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGeaiemkpnrkgq 78
Cdd:PRK13635 1 MKEEIIRVEHISFRYPDAAtyALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGG------------ 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 79 nRPSNLKQIDRIRTQLGMVFQN-FNLWSHKTV-------LENIieapvhvlKRPQAECVEHAEQLLEKVGLADKRHYYPA 150
Cdd:PRK13635 69 -MVLSEETVWDVRRQVGMVFQNpDNQFVGATVqddvafgLENI--------GVPREEMVERVDQALRQVGMEDFLNREPH 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 151 HLSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGM-TMLVVTHEMDFAREvSNRIVFLHQGEI 229
Cdd:PRK13635 140 RLSGGQKQRVAIAGVLALQPDIIILDEATSMLDPRGRREVLETVRQLKEQKGiTVLSITHDLDEAAQ-ADRVIVMNKGEI 218
|
250
....*....|....
gi 497963481 230 EEQGTPEHVFTASQ 243
Cdd:PRK13635 219 LEEGTPEEIFKSGH 232
|
|
| PRK13651 |
PRK13651 |
cobalt transporter ATP-binding subunit; Provisional |
6-235 |
2.52e-50 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184210 [Multi-domain] Cd Length: 305 Bit Score: 166.80 E-value: 2.52e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGS-----LDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEI--IVGGEAIEMKPNRK-- 76
Cdd:PRK13651 3 IKVKNIVKIFNKklpteLKALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIewIFKDEKNKKKTKEKek 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 77 -------GQNRPSNLKQIDRIRTQLGMVFQ--NFNLWShKTVLENIIEAPVHvLKRPQAECVEHAEQLLEKVGLAD---K 144
Cdd:PRK13651 83 vleklviQKTRFKKIKKIKEIRRRVGVVFQfaEYQLFE-QTIEKDIIFGPVS-MGVSKEEAKKRAAKYIELVGLDEsylQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 145 RHyyPAHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFL 224
Cdd:PRK13651 161 RS--PFELSGGQKRRVALAGILAMEPDFLVFDEPTAGLDPQGVKEILEIFDNLNKQGKTIILVTHDLDNVLEWTKRTIFF 238
|
250
....*....|.
gi 497963481 225 HQGEIEEQGTP 235
Cdd:PRK13651 239 KDGKIIKDGDT 249
|
|
| cbiO |
PRK13639 |
cobalt transporter ATP-binding subunit; Provisional |
6-246 |
5.95e-49 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 162.55 E-value: 5.95e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSF--GSLdVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEMkpnrkgqnrpsN 83
Cdd:PRK13639 2 LETRDLKYSYpdGTE-ALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEPIKY-----------D 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 84 LKQIDRIRTQLGMVFQNFN--LWShKTVLENIIEAPVHvLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAA 161
Cdd:PRK13639 70 KKSLLEVRKTVGIVFQNPDdqLFA-PTVEEDVAFGPLN-LGLSKEEVEKRVKEALKAVGMEGFENKPPHHLSGGQKKRVA 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 162 IARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVFTA 241
Cdd:PRK13639 148 IAGILAMKPEIIVLDEPTSGLDPMGASQIMKLLYDLNKEGITIIISTHDVDLVPVYADKVYVMSDGKIIKEGTPKEVFSD 227
|
....*
gi 497963481 242 SQSAR 246
Cdd:PRK13639 228 IETIR 232
|
|
| SunT |
COG2274 |
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ... |
4-238 |
1.28e-48 |
|
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];
Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 170.40 E-value: 1.28e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 4 PAISLRNIHKSFGSLD--VLKGISIEANQGEVISILGSSGSGKSTLLRC-SNLLElPDQGEIIVGGEaiemkpnrkgqnr 80
Cdd:COG2274 472 GDIELENVSFRYPGDSppVLDNISLTIKPGERVAIVGRSGSGKSTLLKLlLGLYE-PTSGRILIDGI------------- 537
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 81 psNLKQIDR--IRTQLGMVFQNFNLWShKTVLENIieapvhVLKRPQAEcVEHAEQLLEKVGLAD--KRHyyP------- 149
Cdd:COG2274 538 --DLRQIDPasLRRQIGVVLQDVFLFS-GTIRENI------TLGDPDAT-DEEIIEAARLAGLHDfiEAL--Pmgydtvv 605
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 150 ----AHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLAdEGMTMLVVTHEMDFAREVsNRIVFLH 225
Cdd:COG2274 606 geggSNLSGGQRQRLAIARALLRNPRILILDEATSALDAETEAIILENLRRLL-KGRTVIIIAHRLSTIRLA-DRIIVLD 683
|
250
....*....|...
gi 497963481 226 QGEIEEQGTPEHV 238
Cdd:COG2274 684 KGRIVEDGTHEEL 696
|
|
| ABC_ModC_like |
cd03299 |
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ... |
6-251 |
1.82e-48 |
|
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 159.81 E-value: 1.82e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLdVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIemkpnrkgqnrpSNLK 85
Cdd:cd03299 1 LKVENLSKDWKEF-KLKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKDI------------TNLP 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 86 QIDRirtQLGMVFQNFNLWSHKTVLENIiEAPVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIARA 165
Cdd:cd03299 68 PEKR---DISYVPQNYALFPHMTVYKNI-AYGLKKRKVDKKEIERKVLEIAEMLGIDHLLNRKPETLSGGEQQRVAIARA 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 166 LAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVFTASQS 244
Cdd:cd03299 144 LVVNPKILLLDEPFSALDVRTKEKLREELKKIRKEfGVTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPEEVFKKPKN 223
|
....*..
gi 497963481 245 ARFRQFI 251
Cdd:cd03299 224 EFVAEFL 230
|
|
| proV |
TIGR01186 |
glycine betaine/L-proline transport ATP binding subunit; This model describes the glycine ... |
13-251 |
2.25e-48 |
|
glycine betaine/L-proline transport ATP binding subunit; This model describes the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Functionally, this transport system is involved in osmoregulation. Under conditions of stress, the organism recruits these transport system to accumulate glycine betaine and other solutes which offer osmo-protection. It has been demonstrated that glycine betaine uptake is accompanied by symport with sodium ions. The locus has been named variously as proU or opuA. A gene library from L.lactis functionally complements an E.coli proU mutant. The comlementing locus is similar to a opuA locus in B.sutlis. This clarifies the differences in nomenclature. [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 130254 [Multi-domain] Cd Length: 363 Bit Score: 163.48 E-value: 2.25e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 13 KSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAI-EMKPNRKGQNRpsnlkqidriR 91
Cdd:TIGR01186 1 KKTGGKKGVNDADLAIAKGEIFVIMGLSGSGKSTTVRMLNRLIEPTAGQIFIDGENImKQSPVELREVR----------R 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 92 TQLGMVFQNFNLWSHKTVLENIIEAPvHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIARALAMEPK 171
Cdd:TIGR01186 71 KKIGMVFQQFALFPHMTILQNTSLGP-ELLGWPEQERKEKALELLKLVGLEEYEHRYPDELSGGMQQRVGLARALAAEPD 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 172 VMLFDEPTSALDP----ELVGEVLRVMRTLadeGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVFTASQSARF 247
Cdd:TIGR01186 150 ILLMDEAFSALDPlirdSMQDELKKLQATL---QKTIVFITHDLDEAIRIGDRIVIMKAGEIVQVGTPDEILRNPANEYV 226
|
....
gi 497963481 248 RQFI 251
Cdd:TIGR01186 227 EEFI 230
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
7-228 |
1.07e-47 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 155.48 E-value: 1.07e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 7 SLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEMKPNRkgqnrpsnlkq 86
Cdd:cd00267 1 EIENLSFRYGGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKLPLE----------- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 87 idRIRTQLGMVFQnfnlwshktvleniieapvhvlkrpqaecvehaeqllekvgladkrhyypahLSGGQQQRAAIARAL 166
Cdd:cd00267 70 --ELRRRIGYVPQ----------------------------------------------------LSGGQRQRVALARAL 95
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 497963481 167 AMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGE 228
Cdd:cd00267 96 LLNPDLLLLDEPTSGLDPASRERLLELLRELAEEGRTVIIVTHDPELAELAADRVIVLKDGK 157
|
|
| LivF |
COG0410 |
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ... |
3-236 |
2.43e-47 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];
Pssm-ID: 440179 [Multi-domain] Cd Length: 236 Bit Score: 157.07 E-value: 2.43e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 3 TPAISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRC-SNLLElPDQGEIIVGGEAIE-MKPNRkgqnr 80
Cdd:COG0410 1 MPMLEVENLHAGYGGIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAiSGLLP-PRSGSIRFDGEDITgLPPHR----- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 81 psnlkqidRIRTQLGMVFQNFNLWSHKTVLENIiEAPVHVLKRPQAecvehAEQLLEKVG-----LADKRHYYPAHLSGG 155
Cdd:COG0410 75 --------IARLGIGYVPEGRRIFPSLTVEENL-LLGAYARRDRAE-----VRADLERVYelfprLKERRRQRAGTLSGG 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 156 QQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTP 235
Cdd:COG0410 141 EQQMLAIGRALMSRPKLLLLDEPSLGLAPLIVEEIFEIIRRLNREGVTILLVEQNARFALEIADRAYVLERGRIVLEGTA 220
|
.
gi 497963481 236 E 236
Cdd:COG0410 221 A 221
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
3-253 |
2.95e-47 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 164.09 E-value: 2.95e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 3 TPAISLRNIHKSF-----------GSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCsnLLEL-PDQGEIIVGGEAIE 70
Cdd:COG4172 273 PPLLEARDLKVWFpikrglfrrtvGHVKAVDGVSLTLRRGETLGLVGESGSGKSTLGLA--LLRLiPSEGEIRFDGQDLD 350
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 71 MKPNRkgQNRPsnlkqidrIRTQLGMVFQN----FN--LwshkTVLEnIIEAPVHVLKRPQ--AECVEHAEQLLEKVGL- 141
Cdd:COG4172 351 GLSRR--ALRP--------LRRRMQVVFQDpfgsLSprM----TVGQ-IIAEGLRVHGPGLsaAERRARVAEALEEVGLd 415
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 142 ADKRHYYPAHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNR 220
Cdd:COG4172 416 PAARHRYPHEFSGGQRQRIAIARALILEPKLLVLDEPTSALDVSVQAQILDLLRDLQREhGLAYLFISHDLAVVRALAHR 495
|
250 260 270
....*....|....*....|....*....|...
gi 497963481 221 IVFLHQGEIEEQGTPEHVFTASQSARFRQFIAS 253
Cdd:COG4172 496 VMVMKDGKVVEQGPTEQVFDAPQHPYTRALLAA 528
|
|
| ABC_FtsE |
cd03292 |
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ... |
6-229 |
6.34e-47 |
|
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages
Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 155.26 E-value: 6.34e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSF-GSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIemkpnrkgqnrpSNL 84
Cdd:cd03292 1 IEFINVTKTYpNGTAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDV------------SDL 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 85 K--QIDRIRTQLGMVFQNFNLWSHKTVLENIIeAPVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAI 162
Cdd:cd03292 69 RgrAIPYLRRKIGVVFQDFRLLPDRNVYENVA-FALEVTGVPPREIRKRVPAALELVGLSHKHRALPAELSGGEQQRVAI 147
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 497963481 163 ARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEI 229
Cdd:cd03292 148 ARAIVNSPTILIADEPTGNLDPDTTWEIMNLLKKINKAGTTVVVATHAKELVDTTRHRVIALERGKL 214
|
|
| ABC_Iron-Siderophores_B12_Hemin |
cd03214 |
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ... |
7-233 |
9.82e-47 |
|
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.
Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 153.75 E-value: 9.82e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 7 SLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRC-SNLLElPDQGEIIVGGEAI-EMKPnrkgqnrpsnl 84
Cdd:cd03214 1 EVENLSVGYGGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTlAGLLK-PSSGEILLDGKDLaSLSP----------- 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 85 KQIDRIRTQLgmvfqnfnlwshktvleniieapvhvlkrPQAecvehaeqlLEKVGLADKRHYYPAHLSGGQQQRAAIAR 164
Cdd:cd03214 69 KELARKIAYV-----------------------------PQA---------LELLGLAHLADRPFNELSGGERQRVLLAR 110
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 165 ALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQG 233
Cdd:cd03214 111 ALAQEPPILLLDEPTSHLDIAHQIELLELLRRLARErGKTVVMVLHDLNLAARYADRVILLKDGRIVAQG 180
|
|
| heterocyst_DevA |
TIGR02982 |
ABC exporter ATP-binding subunit, DevA family; Members of this protein family are found mostly ... |
5-229 |
4.39e-46 |
|
ABC exporter ATP-binding subunit, DevA family; Members of this protein family are found mostly in the Cyanobacteria, but also in the Planctomycetes. Cyanobacterial examples are involved in heterocyst formation, by which some fraction of members of the colony undergo a developmental change and become capable of nitrogen fixation. The DevBCA proteins are thought export of either heterocyst-specific glycolipids or an enzyme essential for formation of the laminated layer found in heterocysts.
Pssm-ID: 274374 [Multi-domain] Cd Length: 220 Bit Score: 153.25 E-value: 4.39e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 5 AISLRNIHKSFGSLD----VLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIemkpnrKGQNR 80
Cdd:TIGR02982 1 VISIRNLNHYYGHGSlrkqVLFDINLEINPGEIVILTGPSGSGKTTLLTLIGGLRSVQEGSLKVLGQEL------HGASK 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 81 psnlKQIDRIRTQLGMVFQNFNLWSHKTVLENIIEAPVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRA 160
Cdd:TIGR02982 75 ----KQLVQLRRRIGYIFQAHNLLGFLTARQNVQMALELQPNLSYQEARERARAMLEAVGLGDHLNYYPHNLSGGQKQRV 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 497963481 161 AIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLA-DEGMTMLVVTHE---MDfareVSNRIVFLHQGEI 229
Cdd:TIGR02982 151 AIARALVHHPKLVLADEPTAALDSKSGRDVVELMQKLAkEQGCTILMVTHDnriLD----VADRILQMEDGKL 219
|
|
| ABC_Metallic_Cations |
cd03235 |
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ... |
14-224 |
5.86e-46 |
|
ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.
Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 152.69 E-value: 5.86e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 14 SFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCsnLLEL--PDQGEIIVGGEAIEMKPNRKG---QNRpsnlkQID 88
Cdd:cd03235 8 SYGGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKA--ILGLlkPTSGSIRVFGKPLEKERKRIGyvpQRR-----SID 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 89 R-----IRTQLGMvfqnfNLWSHKTVLeniieapvhvlKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIA 163
Cdd:cd03235 81 RdfpisVRDVVLM-----GLYGHKGLF-----------RRLSKADKAKVDEALERVGLSELADRQIGELSGGQQQRVLLA 144
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 497963481 164 RALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFL 224
Cdd:cd03235 145 RALVQDPDLLLLDEPFAGVDPKTQEDIYELLRELRREGMTILVVTHDLGLVLEYFDRVLLL 205
|
|
| ABC_tran |
pfam00005 |
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ... |
21-180 |
6.52e-46 |
|
ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.
Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 150.49 E-value: 6.52e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 21 LKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIemkpnrkgqnrpsNLKQIDRIRTQLGMVFQN 100
Cdd:pfam00005 1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDL-------------TDDERKSLRKEIGYVFQD 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 101 FNLWSHKTVLENIIEaPVHVLKRPQAECVEHAEQLLEKVGLADKRH----YYPAHLSGGQQQRAAIARALAMEPKVMLFD 176
Cdd:pfam00005 68 PQLFPRLTVRENLRL-GLLLKGLSKREKDARAEEALEKLGLGDLADrpvgERPGTLSGGQRQRVAIARALLTKPKLLLLD 146
|
....
gi 497963481 177 EPTS 180
Cdd:pfam00005 147 EPTA 150
|
|
| fbpC |
PRK11432 |
ferric ABC transporter ATP-binding protein; |
8-253 |
1.19e-45 |
|
ferric ABC transporter ATP-binding protein;
Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 156.03 E-value: 1.19e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 8 LRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEmkpNRKGQNRpsnlkqi 87
Cdd:PRK11432 9 LKNITKRFGSNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEDVT---HRSIQQR------- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 88 drirtQLGMVFQNFNLWSHKTVLENIiEAPVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIARALA 167
Cdd:PRK11432 79 -----DICMVFQSYALFPHMSLGENV-GYGLKMLGVPKEERKQRVKEALELVDLAGFEDRYVDQISGGQQQRVALARALI 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 168 MEPKVMLFDEPTSALDPELvgevLRVMRTLADE-----GMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVFTAS 242
Cdd:PRK11432 153 LKPKVLLFDEPLSNLDANL----RRSMREKIRElqqqfNITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIGSPQELYRQP 228
|
250
....*....|.
gi 497963481 243 QSarfrQFIAS 253
Cdd:PRK11432 229 AS----RFMAS 235
|
|
| PRK10535 |
PRK10535 |
macrolide ABC transporter ATP-binding protein/permease MacB; |
3-253 |
6.42e-45 |
|
macrolide ABC transporter ATP-binding protein/permease MacB;
Pssm-ID: 182528 [Multi-domain] Cd Length: 648 Bit Score: 159.50 E-value: 6.42e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 3 TPAISLRNIHKSF----GSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAI-EMKPNRKG 77
Cdd:PRK10535 2 TALLELKDIRRSYpsgeEQVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQDVaTLDADALA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 78 QNRpsnlkqidriRTQLGMVFQNFNLWSHKTVLENIiEAPVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQ 157
Cdd:PRK10535 82 QLR----------REHFGFIFQRYHLLSHLTAAQNV-EVPAVYAGLERKQRLLRAQELLQRLGLEDRVEYQPSQLSGGQQ 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 158 QRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREvSNRIVFLHQGEI-------- 229
Cdd:PRK10535 151 QRVSIARALMNGGQVILADEPTGALDSHSGEEVMAILHQLRDRGHTVIIVTHDPQVAAQ-AERVIEIRDGEIvrnppaqe 229
|
250 260
....*....|....*....|....*.
gi 497963481 230 --EEQGTPEHVFTASQSarFRQFIAS 253
Cdd:PRK10535 230 kvNVAGGTEPVVNTASG--WRQFVSG 253
|
|
| ModC |
COG4148 |
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ... |
10-249 |
2.16e-44 |
|
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis
Pssm-ID: 443319 [Multi-domain] Cd Length: 358 Bit Score: 152.95 E-value: 2.16e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 10 NIHKSFGS--LDVlkgiSIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEmkPNRKGQNRPSNlkqi 87
Cdd:COG4148 6 DFRLRRGGftLDV----DFTLPGRGVTALFGPSGSGKTTLLRAIAGLERPDSGRIRLGGEVLQ--DSARGIFLPPH---- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 88 driRTQLGMVFQNFNLWSHKTVLENIIEApvhvLKR-PQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIARAL 166
Cdd:COG4148 76 ---RRRIGYVFQEARLFPHLSVRGNLLYG----RKRaPRAERRISFDEVVELLGIGHLLDRRPATLSGGERQRVAIGRAL 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 167 AMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVFTASQSA 245
Cdd:COG4148 149 LSSPRLLLMDEPLAALDLARKAEILPYLERLRDElDIPILYVSHSLDEVARLADHVVLLEQGRVVASGPLAEVLSRPDLL 228
|
....
gi 497963481 246 RFRQ 249
Cdd:COG4148 229 PLAG 232
|
|
| potA |
TIGR01187 |
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ... |
36-253 |
7.45e-44 |
|
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 162242 [Multi-domain] Cd Length: 325 Bit Score: 150.72 E-value: 7.45e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 36 ILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIemkpnrkgQNRPSNLKQIdrirtqlGMVFQNFNLWSHKTVLENIiE 115
Cdd:TIGR01187 1 LLGPSGCGKTTLLRLLAGFEQPDSGSIMLDGEDV--------TNVPPHLRHI-------NMVFQSYALFPHMTVEENV-A 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 116 APVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMR 195
Cdd:TIGR01187 65 FGLKMRKVPRAEIKPRVLEALRLVQLEEFADRKPHQLSGGQQQRVALARALVFKPKILLLDEPLSALDKKLRDQMQLELK 144
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 497963481 196 TLADE-GMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVFTASQSARFRQFIAS 253
Cdd:TIGR01187 145 TIQEQlGITFVFVTHDQEEAMTMSDRIAIMRKGKIAQIGTPEEIYEEPANLFVARFIGE 203
|
|
| ABCC_MRP_Like |
cd03228 |
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ... |
6-228 |
1.70e-43 |
|
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 144.83 E-value: 1.70e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLD--VLKGISIEANQGEVISILGSSGSGKSTLLRC-SNLLElPDQGEIIVGGEaiemkpnrkgqnrps 82
Cdd:cd03228 1 IEFKNVSFSYPGRPkpVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLlLRLYD-PTSGEILIDGV--------------- 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 83 NLKQIDR--IRTQLGMVFQNFNLWShKTVLENIieapvhvlkrpqaecvehaeqllekvgladkrhyypahLSGGQQQRA 160
Cdd:cd03228 65 DLRDLDLesLRKNIAYVPQDPFLFS-GTIRENI--------------------------------------LSGGQRQRI 105
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 497963481 161 AIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADeGMTMLVVTHEMDFAREVsNRIVFLHQGE 228
Cdd:cd03228 106 AIARALLRDPPILILDEATSALDPETEALILEALRALAK-GKTVIVIAHRLSTIRDA-DRIIVLDDGR 171
|
|
| hmuV |
PRK13548 |
hemin importer ATP-binding subunit; Provisional |
4-241 |
2.62e-43 |
|
hemin importer ATP-binding subunit; Provisional
Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 147.23 E-value: 2.62e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 4 PAISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRcsnLL--EL-PDQGEIIVGGEAIE-MKPNRKGQN 79
Cdd:PRK13548 1 AMLEARNLSVRLGGRTLLDDVSLTLRPGEVVAILGPNGAGKSTLLR---ALsgELsPDSGEVRLNGRPLAdWSPAELARR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 80 RpSNLKQidriRTQLGMVFqnfnlwshkTVLEnIIEAPVHVLKRPQAECVEHAEQLLEKVGLADKRH-YYPAhLSGGQQQ 158
Cdd:PRK13548 78 R-AVLPQ----HSSLSFPF---------TVEE-VVAMGRAPHGLSRAEDDALVAAALAQVDLAHLAGrDYPQ-LSGGEQQ 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 159 RAAIARALA------MEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQGEIEE 231
Cdd:PRK13548 142 RVQLARVLAqlwepdGPPRWLLLDEPTSALDLAHQHHVLRLARQLAHErGLAVIVVLHDLNLAARYADRIVLLHQGRLVA 221
|
250
....*....|
gi 497963481 232 QGTPEHVFTA 241
Cdd:PRK13548 222 DGTPAEVLTP 231
|
|
| cbiO |
TIGR01166 |
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of ... |
19-214 |
2.64e-43 |
|
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of the multisubunit cobalt transporter in bacteria and its equivalents in archaea. The model is restricted to ATP subunit that is a part of the cobalt transporter, which belongs to the ABC transporter superfamily (ATP Binding Cassette). The model excludes ATP binding subunit that are associated with other transporters belonging to ABC transporter superfamily. This superfamily includes two groups, one which catalyze the uptake of small molecules, including ions from the external milieu and the other group which is engaged in the efflux of small molecular weight compounds and ions from within the cell. Energy derived from the hydrolysis of ATP drive the both the process of uptake and efflux. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 130234 [Multi-domain] Cd Length: 190 Bit Score: 145.26 E-value: 2.64e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 19 DVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEaiEMKPNRKGqnrpsnlkqIDRIRTQLGMVF 98
Cdd:TIGR01166 6 EVLKGLNFAAERGEVLALLGANGAGKSTLLLHLNGLLRPQSGAVLIDGE--PLDYSRKG---------LLERRQRVGLVF 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 99 QNFN--LWShKTVLENIIEAPVHvLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIARALAMEPKVMLFD 176
Cdd:TIGR01166 75 QDPDdqLFA-ADVDQDVAFGPLN-LGLSEAEVERRVREALTAVGASGLRERPTHCLSGGEKKRVAIAGAVAMRPDVLLLD 152
|
170 180 190
....*....|....*....|....*....|....*...
gi 497963481 177 EPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFA 214
Cdd:TIGR01166 153 EPTAGLDPAGREQMLAILRRLRAEGMTVVISTHDVDLA 190
|
|
| ABC_ATP_DarD |
NF038007 |
darobactin export ABC transporter ATP-binding protein; |
20-229 |
2.77e-43 |
|
darobactin export ABC transporter ATP-binding protein;
Pssm-ID: 411600 [Multi-domain] Cd Length: 218 Bit Score: 146.02 E-value: 2.77e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 20 VLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEmkpnrkgqnrpsNLKQIDRI---RTQLGM 96
Cdd:NF038007 20 VLNHLNFSVEKGDFVSIMGPSGSGKSTLLNIIGMFDSLDSGSLTLAGKEVT------------NLSYSQKIilrRELIGY 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 97 VFQNFNLWSHKTVLENIiEAPVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIARALAMEPKVMLFD 176
Cdd:NF038007 88 IFQSFNLIPHLSIFDNV-ALPLKYRGVAKKERIERVNQVLNLFGIDNRRNHKPMQLSGGQQQRVAIARAMVSNPALLLAD 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 497963481 177 EPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEmDFAREVSNRIVFLHQGEI 229
Cdd:NF038007 167 EPTGNLDSKNARAVLQQLKYINQKGTTIIMVTHS-DEASTYGNRIINMKDGKL 218
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
1-228 |
5.83e-43 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 152.10 E-value: 5.83e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 1 MTTPAISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCsnL--LELPDQGEIIVGGEAIEMK-PNrkg 77
Cdd:COG3845 1 MMPPALELRGITKRFGGVVANDDVSLTVRPGEIHALLGENGAGKSTLMKI--LygLYQPDSGEILIDGKPVRIRsPR--- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 78 qnrpsnlkqiDRIRTQLGMVFQNFNLWSHKTVLENII----EAPVHVLKRPQAEcvEHAEQLLEKVGLA---DKRhyyPA 150
Cdd:COG3845 76 ----------DAIALGIGMVHQHFMLVPNLTVAENIVlglePTKGGRLDRKAAR--ARIRELSERYGLDvdpDAK---VE 140
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 497963481 151 HLSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGE 228
Cdd:COG3845 141 DLSVGEQQRVEILKALYRGARILILDEPTAVLTPQEADELFEILRRLAAEGKSIIFITHKLREVMAIADRVTVLRRGK 218
|
|
| COG4559 |
COG4559 |
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism]; |
6-242 |
6.85e-43 |
|
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443620 [Multi-domain] Cd Length: 258 Bit Score: 146.03 E-value: 6.85e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRcsnLL--EL-PDQGEIIVGGEAIE-MKPNrkgqnrp 81
Cdd:COG4559 2 LEAENLSVRLGGRTLLDDVSLTLRPGELTAIIGPNGAGKSTLLK---LLtgELtPSSGEVRLNGRPLAaWSPW------- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 82 snlkQIDRIR------TQLgmvfqNFNLwshkTVLEnIIE---APVHvlkRPQAECVEHAEQLLEKVGLADKRH-YYPaH 151
Cdd:COG4559 72 ----ELARRRavlpqhSSL-----AFPF----TVEE-VVAlgrAPHG---SSAAQDRQIVREALALVGLAHLAGrSYQ-T 133
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 152 LSGGQQQRAAIARALA-------MEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFL 224
Cdd:COG4559 134 LSGGEQQRVQLARVLAqlwepvdGGPRWLFLDEPTSALDLAHQHAVLRLARQLARRGGGVVAVLHDLNLAAQYADRILLL 213
|
250
....*....|....*...
gi 497963481 225 HQGEIEEQGTPEHVFTAS 242
Cdd:COG4559 214 HQGRLVAQGTPEEVLTDE 231
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
2-229 |
7.21e-43 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 151.71 E-value: 7.21e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 2 TTPAISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEMKPNRKGQnrp 81
Cdd:COG1129 1 AEPLLEMRGISKSFGGVKALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGEPVRFRSPRDAQ--- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 82 snlkqidrirtQLG--MVFQNFNLWSHKTVLENII--EAPVHVLKRPQAECVEHAEQLLEKVGL---ADKRhyyPAHLSG 154
Cdd:COG1129 78 -----------AAGiaIIHQELNLVPNLSVAENIFlgREPRRGGLIDWRAMRRRARELLARLGLdidPDTP---VGDLSV 143
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 497963481 155 GQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEI 229
Cdd:COG1129 144 AQQQLVEIARALSRDARVLILDEPTASLTEREVERLFRIIRRLKAQGVAIIYISHRLDEVFEIADRVTVLRDGRL 218
|
|
| AppF |
COG4608 |
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ... |
1-241 |
9.23e-43 |
|
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443658 [Multi-domain] Cd Length: 329 Bit Score: 147.96 E-value: 9.23e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 1 MTTPAISLRNIHKSF---GSL-----DVLK---GISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAI 69
Cdd:COG4608 3 MAEPLLEVRDLKKHFpvrGGLfgrtvGVVKavdGVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEEPTSGEILFDGQDI 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 70 emkpnrkGQNRPSNLKqidRIRTQLGMVFQN----FNlwSHKTVlENIIEAP--VHVLKrPQAECVEHAEQLLEKVGLaD 143
Cdd:COG4608 83 -------TGLSGRELR---PLRRRMQMVFQDpyasLN--PRMTV-GDIIAEPlrIHGLA-SKAERRERVAELLELVGL-R 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 144 KRHY--YPAHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNR 220
Cdd:COG4608 148 PEHAdrYPHEFSGGQRQRIGIARALALNPKLIVCDEPVSALDVSIQAQVLNLLEDLQDElGLTYLFISHDLSVVRHISDR 227
|
250 260
....*....|....*....|.
gi 497963481 221 IVFLHQGEIEEQGTPEHVFTA 241
Cdd:COG4608 228 VAVMYLGKIVEIAPRDELYAR 248
|
|
| PRK14267 |
PRK14267 |
phosphate ABC transporter ATP-binding protein; Provisional |
5-239 |
2.78e-42 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 144.60 E-value: 2.78e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 5 AISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSN-LLELPD----QGEIIVGGEAI---EMKPnrk 76
Cdd:PRK14267 4 AIETVNLRVYYGSNHVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNrLLELNEearvEGEVRLFGRNIyspDVDP--- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 77 gqnrpsnlkqiDRIRTQLGMVFQNFNLWSHKTVLENI-IEAPVHVLKRPQAECVEHAEQLLEKVGL----ADKRHYYPAH 151
Cdd:PRK14267 81 -----------IEVRREVGMVFQYPNPFPHLTIYDNVaIGVKLNGLVKSKKELDERVEWALKKAALwdevKDRLNDYPSN 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 152 LSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEgMTMLVVTHEMDFAREVSNRIVFLHQGEIEE 231
Cdd:PRK14267 150 LSGGQRQRLVIARALAMKPKILLMDEPTANIDPVGTAKIEELLFELKKE-YTIVLVTHSPAQAARVSDYVAFLYLGKLIE 228
|
....*...
gi 497963481 232 QGTPEHVF 239
Cdd:PRK14267 229 VGPTRKVF 236
|
|
| PRK13633 |
PRK13633 |
energy-coupling factor transporter ATPase; |
20-239 |
3.53e-42 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 145.23 E-value: 3.53e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 20 VLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIemkpnrkgqnrpSNLKQIDRIRTQLGMVFQ 99
Cdd:PRK13633 25 ALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGLDT------------SDEENLWDIRNKAGMVFQ 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 100 NfnlwSHKTVLENIIEAPVHV----LKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIARALAMEPKVMLF 175
Cdd:PRK13633 93 N----PDNQIVATIVEEDVAFgpenLGIPPEEIRERVDESLKKVGMYEYRRHAPHLLSGGQKQRVAIAGILAMRPECIIF 168
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 497963481 176 DEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREvSNRIVFLHQGEIEEQGTPEHVF 239
Cdd:PRK13633 169 DEPTAMLDPSGRREVVNTIKELNKKyGITIILITHYMEEAVE-ADRIIVMDSGKVVMEGTPKEIF 232
|
|
| ABC_Carb_Monos_I |
cd03216 |
First domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
6-229 |
4.83e-42 |
|
First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 141.03 E-value: 4.83e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEMkpnrkgqNRPSnlk 85
Cdd:cd03216 1 LELRGITKRFGGVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKEVSF-------ASPR--- 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 86 qiDRIRTQLGMVFQnfnlwshktvleniieapvhvlkrpqaecvehaeqllekvgladkrhyypahLSGGQQQRAAIARA 165
Cdd:cd03216 71 --DARRAGIAMVYQ----------------------------------------------------LSVGERQMVEIARA 96
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 497963481 166 LAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEI 229
Cdd:cd03216 97 LARNARLLILDEPTAALTPAEVERLFKVIRRLRAQGVAVIFISHRLDEVFEIADRVTVLRDGRV 160
|
|
| ABC_DrrA |
cd03265 |
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ... |
6-236 |
5.70e-42 |
|
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 142.89 E-value: 5.70e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIemkpnrkgqnrpsnLK 85
Cdd:cd03265 1 IEVENLVKKYGDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGHDV--------------VR 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 86 QIDRIRTQLGMVFQNFNLWSHKTVLENI-IEAPVHVLKRpqAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIAR 164
Cdd:cd03265 67 EPREVRRRIGIVFQDLSVDDELTGWENLyIHARLYGVPG--AERRERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIAR 144
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 497963481 165 ALAMEPKVMLFDEPTSALDPELVGEVLRVMRTL-ADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPE 236
Cdd:cd03265 145 SLVHRPEVLFLDEPTIGLDPQTRAHVWEYIEKLkEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGTPE 217
|
|
| potG |
PRK11607 |
putrescine ABC transporter ATP-binding subunit PotG; |
1-253 |
1.24e-41 |
|
putrescine ABC transporter ATP-binding subunit PotG;
Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 146.13 E-value: 1.24e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 1 MTTPAISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEMKPNRKgqnR 80
Cdd:PRK11607 15 ALTPLLEIRNLTKSFDGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVDLSHVPPYQ---R 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 81 PSNlkqidrirtqlgMVFQNFNLWSHKTVLENIIEApvhvLKR---PQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQ 157
Cdd:PRK11607 92 PIN------------MMFQSYALFPHMTVEQNIAFG----LKQdklPKAEIASRVNEMLGLVHMQEFAKRKPHQLSGGQR 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 158 QRAAIARALAMEPKVMLFDEPTSALDPELVGEV-LRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPE 236
Cdd:PRK11607 156 QRVALARSLAKRPKLLLLDEPMGALDKKLRDRMqLEVVDILERVGVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIGEPE 235
|
250
....*....|....*..
gi 497963481 237 HVFTASQSARFRQFIAS 253
Cdd:PRK11607 236 EIYEHPTTRYSAEFIGS 252
|
|
| ABC_cobalt_CbiO_domain2 |
cd03226 |
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ... |
7-229 |
1.97e-41 |
|
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 140.86 E-value: 1.97e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 7 SLRNIHKSFG-SLDVLKGISIEANQGEVISILGSSGSGKSTLLR-CSNLLElPDQGEIIVGGEaiemkpnrkgqnrpsNL 84
Cdd:cd03226 1 RIENISFSYKkGTEILDDLSLDLYAGEIIALTGKNGAGKTTLAKiLAGLIK-ESSGSILLNGK---------------PI 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 85 KQIDRIRTqLGMVFQN--FNLWShKTVLENIIEApvhvlKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAI 162
Cdd:cd03226 65 KAKERRKS-IGYVMQDvdYQLFT-DSVREELLLG-----LKELDAGNEQAETVLKDLDLYALKERHPLSLSGGQKQRLAI 137
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 497963481 163 ARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEI 229
Cdd:cd03226 138 AAALLSGKDLLIFDEPTSGLDYKNMERVGELIRELAAQGKAVIVITHDYEFLAKVCDRVLLLANGAI 204
|
|
| cbiO |
PRK13631 |
cobalt transporter ATP-binding subunit; Provisional |
20-240 |
4.41e-41 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237451 [Multi-domain] Cd Length: 320 Bit Score: 143.45 E-value: 4.41e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 20 VLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEMKPNRKGQNRPSNLKQID---RIRTQLGM 96
Cdd:PRK13631 41 ALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIQVGDIYIGDKKNNHELITNPYSKKIKnfkELRRRVSM 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 97 VFQ--NFNLWShKTVLENIIEAPVhVLKRPQAECVEHAEQLLEKVGLAD---KRHyyPAHLSGGQQQRAAIARALAMEPK 171
Cdd:PRK13631 121 VFQfpEYQLFK-DTIEKDIMFGPV-ALGVKKSEAKKLAKFYLNKMGLDDsylERS--PFGLSGGQKRRVAIAGILAIQPE 196
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 497963481 172 VMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVFT 240
Cdd:PRK13631 197 ILIFDEPTAGLDPKGEHEMMQLILDAKANNKTVFVITHTMEHVLEVADEVIVMDKGKILKTGTPYEIFT 265
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
1-253 |
4.47e-41 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 147.52 E-value: 4.47e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 1 MTTPAISLRNIHKSFGSLD----VLKGISIEANQGEVISILGSSGSGKS----TLLRcsnLLELPD---QGEIIVGGEAI 69
Cdd:COG4172 2 MSMPLLSVEDLSVAFGQGGgtveAVKGVSFDIAAGETLALVGESGSGKSvtalSILR---LLPDPAahpSGSILFDGQDL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 70 EMKPNRkgqnrpsnlkQIDRIR-TQLGMVFQ------NfnlwSHKTVLENIIEA-PVH-VLKRPQAEcvEHAEQLLEKVG 140
Cdd:COG4172 79 LGLSER----------ELRRIRgNRIAMIFQepmtslN----PLHTIGKQIAEVlRLHrGLSGAAAR--ARALELLERVG 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 141 LAD-KRHY--YPAHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTL-ADEGMTMLVVTHEMDFARE 216
Cdd:COG4172 143 IPDpERRLdaYPHQLSGGQRQRVMIAMALANEPDLLIADEPTTALDVTVQAQILDLLKDLqRELGMALLLITHDLGVVRR 222
|
250 260 270
....*....|....*....|....*....|....*..
gi 497963481 217 VSNRIVFLHQGEIEEQGTPEHVFTASQSARFRQFIAS 253
Cdd:COG4172 223 FADRVAVMRQGEIVEQGPTAELFAAPQHPYTRKLLAA 259
|
|
| MdlB |
COG1132 |
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]; |
5-236 |
5.13e-41 |
|
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 148.00 E-value: 5.13e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 5 AISLRNIhkSF---GSLDVLKGISIEANQGEVISILGSSGSGKSTLLrcsNLLE---LPDQGEIIVGGEaiemkpnrkgq 78
Cdd:COG1132 339 EIEFENV--SFsypGDRPVLKDISLTIPPGETVALVGPSGSGKSTLV---NLLLrfyDPTSGRILIDGV----------- 402
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 79 nrpsNLKQIDR--IRTQLGMVFQNFNLWsHKTVLENIIeapvhvLKRPQA--ECVEHAeqlLEKVGLADKRHYYP----- 149
Cdd:COG1132 403 ----DIRDLTLesLRRQIGVVPQDTFLF-SGTIRENIR------YGRPDAtdEEVEEA---AKAAQAHEFIEALPdgydt 468
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 150 ------AHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLAdEGMTMLVVTH------EMDfarev 217
Cdd:COG1132 469 vvgergVNLSGGQRQRIAIARALLKDPPILILDEATSALDTETEALIQEALERLM-KGRTTIVIAHrlstirNAD----- 542
|
250
....*....|....*....
gi 497963481 218 snRIVFLHQGEIEEQGTPE 236
Cdd:COG1132 543 --RILVLDDGRIVEQGTHE 559
|
|
| CydC |
COG4987 |
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ... |
2-252 |
6.08e-41 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444011 [Multi-domain] Cd Length: 569 Bit Score: 147.61 E-value: 6.08e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 2 TTPAISLRNIHKSF--GSLDVLKGISIEANQGEVISILGSSGSGKSTLLrcsNLL---ELPDQGEIIVGGEaiemkpnrk 76
Cdd:COG4987 330 GGPSLELEDVSFRYpgAGRPVLDGLSLTLPPGERVAIVGPSGSGKSTLL---ALLlrfLDPQSGSITLGGV--------- 397
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 77 gqnrpsNLKQIDR--IRTQLGMVFQNFNLWSHkTVLENIIeapvhvLKRPQAEcVEHAEQLLEKVGLADKRHYYP----- 149
Cdd:COG4987 398 ------DLRDLDEddLRRRIAVVPQRPHLFDT-TLRENLR------LARPDAT-DEELWAALERVGLGDWLAALPdgldt 463
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 150 ------AHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLAdEGMTMLVVTHEMDFAREVsNRIVF 223
Cdd:COG4987 464 wlgeggRRLSGGERRRLALARALLRDAPILLLDEPTEGLDAATEQALLADLLEAL-AGRTVLLITHRLAGLERM-DRILV 541
|
250 260
....*....|....*....|....*....
gi 497963481 224 LHQGEIEEQGTPEHVftASQSARFRQFIA 252
Cdd:COG4987 542 LEDGRIVEQGTHEEL--LAQNGRYRQLYQ 568
|
|
| urea_trans_UrtE |
TIGR03410 |
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC ... |
7-252 |
6.86e-41 |
|
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 274567 [Multi-domain] Cd Length: 230 Bit Score: 140.35 E-value: 6.86e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 7 SLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIE-MKPNRkgqnrpsnlk 85
Cdd:TIGR03410 2 EVSNLNVYYGQSHILRGVSLEVPKGEVTCVLGRNGVGKTTLLKTLMGLLPVKSGSIRLDGEDITkLPPHE---------- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 86 qidRIRTQLGMVFQNFNLWSHKTVLENIiEAPVHVLKRPQAECVEHAEQLLEKvgLADKRHYYPAHLSGGQQQRAAIARA 165
Cdd:TIGR03410 72 ---RARAGIAYVPQGREIFPRLTVEENL-LTGLAALPRRSRKIPDEIYELFPV--LKEMLGRRGGDLSGGQQQQLAIARA 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 166 LAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVftasQS 244
Cdd:TIGR03410 146 LVTRPKLLLLDEPTEGIQPSIIKDIGRVIRRLRAEgGMAILLVEQYLDFARELADRYYVMERGRVVASGAGDEL----DE 221
|
....*...
gi 497963481 245 ARFRQFIA 252
Cdd:TIGR03410 222 DKVRRYLA 229
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
6-238 |
9.85e-41 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 146.49 E-value: 9.85e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTL---LRCSNLLElPDQGEIIVGGEAIEM-----KPNRKG 77
Cdd:TIGR03269 1 IEVKNLTKKFDGKEVLKNISFTIEEGEVLGILGRSGAGKSVLmhvLRGMDQYE-PTSGRIIYHVALCEKcgyveRPSKVG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 78 QNRP---SNLKQID------------RIRTQLGMVFQ-NFNLWSHKTVLENIIEApVHVLKRPQAECVEHAEQLLEKVGL 141
Cdd:TIGR03269 80 EPCPvcgGTLEPEEvdfwnlsdklrrRIRKRIAIMLQrTFALYGDDTVLDNVLEA-LEEIGYEGKEAVGRAVDLIEMVQL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 142 ADKRHYYPAHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDPE---LVGEVLRvmRTLADEGMTMLVVTHEMDFAREVS 218
Cdd:TIGR03269 159 SHRITHIARDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQtakLVHNALE--EAVKASGISMVLTSHWPEVIEDLS 236
|
250 260
....*....|....*....|
gi 497963481 219 NRIVFLHQGEIEEQGTPEHV 238
Cdd:TIGR03269 237 DKAIWLENGEIKEEGTPDEV 256
|
|
| PRK14247 |
PRK14247 |
phosphate ABC transporter ATP-binding protein; Provisional |
6-240 |
1.76e-40 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172735 [Multi-domain] Cd Length: 250 Bit Score: 139.66 E-value: 1.76e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSN-LLEL-PD---QGEIIVGGEAIEMKPnrkgqnr 80
Cdd:PRK14247 4 IEIRDLKVSFGQVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNrLIELyPEarvSGEVYLDGQDIFKMD------- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 81 psnlkqIDRIRTQLGMVFQNFNLWSHKTVLENIIEAP-VHVLKRPQAECVEHAEQLLEKVGLADK---RHYYPA-HLSGG 155
Cdd:PRK14247 77 ------VIELRRRVQMVFQIPNPIPNLSIFENVALGLkLNRLVKSKKELQERVRWALEKAQLWDEvkdRLDAPAgKLSGG 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 156 QQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEgMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTP 235
Cdd:PRK14247 151 QQQRLCIARALAFQPEVLLADEPTANLDPENTAKIESLFLELKKD-MTIVLVTHFPQQAARISDYVAFLYKGQIVEWGPT 229
|
....*
gi 497963481 236 EHVFT 240
Cdd:PRK14247 230 REVFT 234
|
|
| cbiO |
PRK13652 |
cobalt transporter ATP-binding subunit; Provisional |
6-240 |
2.44e-40 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 140.32 E-value: 2.44e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNI-HKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEMKpnrkgqnrpsNL 84
Cdd:PRK13652 4 IETRDLcYSYSGSKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPITKE----------NI 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 85 KQIdriRTQLGMVFQNFN--LWShKTVLENIIEAPVHVlkRPQAECVEH-AEQLLEKVGLADKRHYYPAHLSGGQQQRAA 161
Cdd:PRK13652 74 REV---RKFVGLVFQNPDdqIFS-PTVEQDIAFGPINL--GLDEETVAHrVSSALHMLGLEELRDRVPHHLSGGEKKRVA 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 162 IARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVFT 240
Cdd:PRK13652 148 IAGVIAMEPQVLVLDEPTAGLDPQGVKELIDFLNDLPETyGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTVEEIFL 227
|
|
| PRK14258 |
PRK14258 |
phosphate ABC transporter ATP-binding protein; Provisional |
4-253 |
3.55e-40 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184593 [Multi-domain] Cd Length: 261 Bit Score: 139.40 E-value: 3.55e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 4 PAISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLL-ELpdQGEIIVGGEaIEMKpnrkGQNRPS 82
Cdd:PRK14258 6 PAIKVNNLSFYYDTQKILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMnEL--ESEVRVEGR-VEFF----NQNIYE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 83 NLKQIDRIRTQLGMVFQNFNLWShKTVLENIIEAPVHVLKRPQAECVEHAEQLLEKVGLAD----KRHYYPAHLSGGQQQ 158
Cdd:PRK14258 79 RRVNLNRLRRQVSMVHPKPNLFP-MSVYDNVAYGVKIVGWRPKLEIDDIVESALKDADLWDeikhKIHKSALDLSGGQQQ 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 159 RAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLA-DEGMTMLVVTHEMDFAREVSNRIVFLHQ-----GEIEEQ 232
Cdd:PRK14258 158 RLCIARALAVKPKVLLMDEPCFGLDPIASMKVESLIQSLRlRSELTMVIVSHNLHQVSRLSDFTAFFKGnenriGQLVEF 237
|
250 260
....*....|....*....|.
gi 497963481 233 GTPEHVFTASQSARFRQFIAS 253
Cdd:PRK14258 238 GLTKKIFNSPHDSRTREYVLS 258
|
|
| cbiO |
PRK13637 |
energy-coupling factor transporter ATPase; |
21-239 |
6.45e-40 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 139.41 E-value: 6.45e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 21 LKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEMKpnrkgqnrpsNLKQIDrIRTQLGMVFQ- 99
Cdd:PRK13637 23 LDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGVDITDK----------KVKLSD-IRKKVGLVFQy 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 100 -NFNLWsHKTVLENIIEAPVHvLKRPQAECVEHAEQLLEKVGL-----ADKRhyyPAHLSGGQQQRAAIARALAMEPKVM 173
Cdd:PRK13637 92 pEYQLF-EETIEKDIAFGPIN-LGLSEEEIENRVKRAMNIVGLdyedyKDKS---PFELSGGQKRRVAIAGVVAMEPKIL 166
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 497963481 174 LFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVF 239
Cdd:PRK13637 167 ILDEPTAGLDPKGRDEILNKIKELHKEyNMTIILVSHSMEDVAKLADRIIVMNKGKCELQGTPREVF 233
|
|
| ABC_subfamily_A |
cd03263 |
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ... |
6-237 |
7.92e-40 |
|
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.
Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 137.25 E-value: 7.92e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLD--VLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIemkpnrkgqnrpsn 83
Cdd:cd03263 1 LQIRNLTKTYKKGTkpAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGYSI-------------- 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 84 LKQIDRIRTQLGMVFQNFNLWSHKTVLENI-IEAPVHVLkrPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAI 162
Cdd:cd03263 67 RTDRKAARQSLGYCPQFDALFDELTVREHLrFYARLKGL--PKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSL 144
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 497963481 163 ARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLAdEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEH 237
Cdd:cd03263 145 AIALIGGPSVLLLDEPTSGLDPASRRAIWDLILEVR-KGRSIILTTHSMDEAEALCDRIAIMSDGKLRCIGSPQE 218
|
|
| cbiO |
PRK13634 |
cobalt transporter ATP-binding subunit; Provisional |
21-239 |
9.03e-40 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 139.00 E-value: 9.03e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 21 LKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEmkpnrkGQNRPSNLKqidRIRTQLGMVFQ- 99
Cdd:PRK13634 23 LYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTIGERVIT------AGKKNKKLK---PLRKKVGIVFQf 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 100 -NFNLWsHKTVLENIIEAPVHvLKRPQAECVEHAEQLLEKVGL-ADKRHYYPAHLSGGQQQRAAIARALAMEPKVMLFDE 177
Cdd:PRK13634 94 pEHQLF-EETVEKDICFGPMN-FGVSEEDAKQKAREMIELVGLpEELLARSPFELSGGQMRRVAIAGVLAMEPEVLVLDE 171
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 497963481 178 PTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVF 239
Cdd:PRK13634 172 PTAGLDPKGRKEMMEMFYKLHKEkGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTPREIF 234
|
|
| ABC_ThiQ_thiamine_transporter |
cd03298 |
ATP-binding cassette domain of the thiamine transport system; Part of the ... |
30-233 |
9.09e-40 |
|
ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 136.85 E-value: 9.09e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 30 QGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGG-EAIEMKPNRkgqnRPsnlkqidrirtqLGMVFQNFNLWSHKT 108
Cdd:cd03298 23 QGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGvDVTAAPPAD----RP------------VSMLFQENNLFAHLT 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 109 VLENIIEAPVHVLKRpQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVG 188
Cdd:cd03298 87 VEQNVGLGLSPGLKL-TAEDRQAIEVALARVGLAGLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFAALDPALRA 165
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 497963481 189 EVLRVMRTL-ADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQG 233
Cdd:cd03298 166 EMLDLVLDLhAETKMTVLMVTHQPEDAKRLAQRVVFLDNGRIAAQG 211
|
|
| ugpC |
PRK11650 |
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC; |
5-239 |
9.11e-40 |
|
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
Pssm-ID: 236947 [Multi-domain] Cd Length: 356 Bit Score: 140.75 E-value: 9.11e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 5 AISLRNIHKSF-GSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAI-EMKPNrkgqnrps 82
Cdd:PRK11650 3 GLKLQAVRKSYdGKTQVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWIGGRVVnELEPA-------- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 83 nlkqiDRirtQLGMVFQNFNLWSHKTVLENIIEApvhvLK-R--PQAEC---VEHAEQLLEKVGLADKRhyyPAHLSGGQ 156
Cdd:PRK11650 75 -----DR---DIAMVFQNYALYPHMSVRENMAYG----LKiRgmPKAEIeerVAEAARILELEPLLDRK---PRELSGGQ 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 157 QQRAAIARALAMEPKVMLFDEPTSALDPELVG----EVLRVMRTLadeGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQ 232
Cdd:PRK11650 140 RQRVAMGRAIVREPAVFLFDEPLSNLDAKLRVqmrlEIQRLHRRL---KTTSLYVTHDQVEAMTLADRVVVMNGGVAEQI 216
|
....*..
gi 497963481 233 GTPEHVF 239
Cdd:PRK11650 217 GTPVEVY 223
|
|
| ABC_YhbG |
cd03218 |
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ... |
6-240 |
1.35e-39 |
|
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.
Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 136.90 E-value: 1.35e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEMKPnrkgqnrpsnlk 85
Cdd:cd03218 1 LRAENLSKRYGKRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDITKLP------------ 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 86 qIDRiRTQLGMVF--QNFNLWSHKTVLENIIeAPVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIA 163
Cdd:cd03218 69 -MHK-RARLGIGYlpQEASIFRKLTVEENIL-AVLEIRGLSKKEREEKLEELLEEFHITHLRKSKASSLSGGERRRVEIA 145
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 497963481 164 RALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVFT 240
Cdd:cd03218 146 RALATNPKFLLLDEPFAGVDPIAVQDIQKIIKILKDRGIGVLITDHNVRETLSITDRAYIIYEGKVLAEGTPEEIAA 222
|
|
| ntrCD |
TIGR01184 |
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ... |
21-227 |
1.64e-39 |
|
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]
Pssm-ID: 130252 [Multi-domain] Cd Length: 230 Bit Score: 136.83 E-value: 1.64e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 21 LKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAI-EMKPNRKgqnrpsnlkqidrirtqlgMVFQ 99
Cdd:TIGR01184 1 LKGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILEGKQItEPGPDRM-------------------VVFQ 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 100 NFNLWSHKTVLENIIEAPVHVLK-RPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIARALAMEPKVMLFDEP 178
Cdd:TIGR01184 62 NYSLLPWLTVRENIALAVDRVLPdLSKSERRAIVEEHIALVGLTEAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEP 141
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 497963481 179 TSALDPELVGEVL-RVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQG 227
Cdd:TIGR01184 142 FGALDALTRGNLQeELMQIWEEHRVTVLMVTHDVDEALLLSDRVVMLTNG 191
|
|
| ABC_ModC_molybdenum_transporter |
cd03297 |
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ... |
11-233 |
1.72e-39 |
|
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 136.27 E-value: 1.72e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 11 IHKSFGSLDvLKgISIEANqGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAieMKPNRKGQNRPSNLKQIdri 90
Cdd:cd03297 6 IEKRLPDFT-LK-IDFDLN-EEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGTV--LFDSRKKINLPPQQRKI--- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 91 rtqlGMVFQNFNLWSHKTVLENIieapVHVLKRP-QAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIARALAME 169
Cdd:cd03297 78 ----GLVFQQYALFPHLNVRENL----AFGLKRKrNREDRISVDELLDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQ 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 497963481 170 PKVMLFDEPTSALDPELVGEVLRVMR-TLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQG 233
Cdd:cd03297 150 PELLLLDEPFSALDRALRLQLLPELKqIKKNLNIPVIFVTHDLSEAEYLADRIVVMEDGRLQYIG 214
|
|
| cbiO |
PRK13650 |
energy-coupling factor transporter ATPase; |
21-239 |
2.00e-39 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 137.94 E-value: 2.00e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 21 LKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIemkpnrkgqnrpsNLKQIDRIRTQLGMVFQN 100
Cdd:PRK13650 23 LNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGDLL-------------TEENVWDIRHKIGMVFQN 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 101 -FNLWSHKTV-------LENiieapvhvLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIARALAMEPKV 172
Cdd:PRK13650 90 pDNQFVGATVeddvafgLEN--------KGIPHEEMKERVNEALELVGMQDFKEREPARLSGGQKQRVAIAGAVAMRPKI 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 173 MLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDfarEV--SNRIVFLHQGEIEEQGTPEHVF 239
Cdd:PRK13650 162 IILDEATSMLDPEGRLELIKTIKGIRDDyQMTVISITHDLD---EValSDRVLVMKNGQVESTSTPRELF 228
|
|
| drrA |
TIGR01188 |
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin ... |
13-236 |
3.66e-39 |
|
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other]
Pssm-ID: 130256 [Multi-domain] Cd Length: 302 Bit Score: 137.91 E-value: 3.66e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 13 KSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIemkpnrkgqnrpsnLKQIDRIRT 92
Cdd:TIGR01188 1 KVYGDFKAVDGVNFKVREGEVFGFLGPNGAGKTTTIRMLTTLLRPTSGTARVAGYDV--------------VREPRKVRR 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 93 QLGMVFQNFNLWSHKTVLENI-IEAPVHVLKRPQAEcvEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIARALAMEPK 171
Cdd:TIGR01188 67 SIGIVPQYASVDEDLTGRENLeMMGRLYGLPKDEAE--ERAEELLELFELGEAADRPVGTYSGGMRRRLDIAASLIHQPD 144
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 497963481 172 VMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPE 236
Cdd:TIGR01188 145 VLFLDEPTTGLDPRTRRAIWDYIRALKEEGVTILLTTHYMEEADKLCDRIAIIDHGRIIAEGTPE 209
|
|
| cbiO |
PRK13636 |
cobalt transporter ATP-binding subunit; Provisional |
21-246 |
4.52e-39 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 136.90 E-value: 4.52e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 21 LKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEMkpNRKGqnrpsnlkqIDRIRTQLGMVFQ- 99
Cdd:PRK13636 22 LKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKPIDY--SRKG---------LMKLRESVGMVFQd 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 100 -NFNLWShKTVLENIIEAPVHvLKRPQAECVEHAEQLLEKVGLADKRHYyPAH-LSGGQQQRAAIARALAMEPKVMLFDE 177
Cdd:PRK13636 91 pDNQLFS-ASVYQDVSFGAVN-LKLPEDEVRKRVDNALKRTGIEHLKDK-PTHcLSFGQKKRVAIAGVLVMEPKVLVLDE 167
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 178 PTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVFTASQSAR 246
Cdd:PRK13636 168 PTAGLDPMGVSEIMKLLVEMQKElGLTIIIATHDIDIVPLYCDNVFVMKEGRVILQGNPKEVFAEKEMLR 237
|
|
| cbiO |
PRK13647 |
cobalt transporter ATP-binding subunit; Provisional |
21-236 |
5.41e-39 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 136.79 E-value: 5.41e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 21 LKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEmkpnrkgqnrPSNLKQIdriRTQLGMVFQN 100
Cdd:PRK13647 21 LKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVN----------AENEKWV---RSKVGLVFQD 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 101 FN--LWShKTVLENIIEAPVHvLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIARALAMEPKVMLFDEP 178
Cdd:PRK13647 88 PDdqVFS-STVWDDVAFGPVN-MGLDKDEVERRVEEALKAVRMWDFRDKPPYHLSYGQKKRVAIAGVLAMDPDVIVLDEP 165
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 497963481 179 TSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPE 236
Cdd:PRK13647 166 MAYLDPRGQETLMEILDRLHNQGKTVIVATHDVDLAAEWADQVIVLKEGRVLAEGDKS 223
|
|
| cbiO |
PRK13632 |
cobalt transporter ATP-binding subunit; Provisional |
3-240 |
6.38e-39 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 136.27 E-value: 6.38e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 3 TPAISLRNIHKSFGSLD--VLKGISIEANQGEVISILGSSGSGKSTLlrcSNLLE---LPDQGEIIVGGEAIEMKpnrkg 77
Cdd:PRK13632 5 SVMIKVENVSFSYPNSEnnALKNVSFEINEGEYVAILGHNGSGKSTI---SKILTgllKPQSGEIKIDGITISKE----- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 78 qnrpsNLKQIdriRTQLGMVFQN-FNLWSHKTV-------LENIieapvhvlKRPQAECVEHAEQLLEKVGLADKRHYYP 149
Cdd:PRK13632 77 -----NLKEI---RKKIGIIFQNpDNQFIGATVeddiafgLENK--------KVPPKKMKDIIDDLAKKVGMEDYLDKEP 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 150 AHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGM-TMLVVTHEMDFAREVSNRIVFLHqGE 228
Cdd:PRK13632 141 QNLSGGQKQRVAIASVLALNPEIIIFDESTSMLDPKGKREIKKIMVDLRKTRKkTLISITHDMDEAILADKVIVFSE-GK 219
|
250
....*....|..
gi 497963481 229 IEEQGTPEHVFT 240
Cdd:PRK13632 220 LIAQGKPKEILN 231
|
|
| CydD |
COG4988 |
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ... |
4-237 |
9.68e-39 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 141.43 E-value: 9.68e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 4 PAISLRNIHKSF-GSLDVLKGISIEANQGEVISILGSSGSGKSTLLRC-SNLLElPDQGEIIVGGEAIemkpnrkgqnrp 81
Cdd:COG4988 335 PSIELEDVSFSYpGGRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLlLGFLP-PYSGSILINGVDL------------ 401
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 82 SNLKQiDRIRTQLGMVFQN---FnlwsHKTVLENIieapvhVLKRPQAEcVEHAEQLLEKVGLADKRHYYP--------- 149
Cdd:COG4988 402 SDLDP-ASWRRQIAWVPQNpylF----AGTIRENL------RLGRPDAS-DEELEAALEAAGLDEFVAALPdgldtplge 469
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 150 --AHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLAdEGMTMLVVTHEMDFAREvSNRIVFLHQG 227
Cdd:COG4988 470 ggRGLSGGQAQRLALARALLRDAPLLLLDEPTAHLDAETEAEILQALRRLA-KGRTVILITHRLALLAQ-ADRILVLDDG 547
|
250
....*....|
gi 497963481 228 EIEEQGTPEH 237
Cdd:COG4988 548 RIVEQGTHEE 557
|
|
| CcmA |
COG4133 |
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ... |
4-218 |
2.59e-38 |
|
ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 132.60 E-value: 2.59e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 4 PAISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCsnL--LELPDQGEIIVGGEAIEmkpnrkgqnrp 81
Cdd:COG4133 1 MMLEAENLSCRRGERLLFSGLSFTLAAGEALALTGPNGSGKTTLLRI--LagLLPPSAGEVLWNGEPIR----------- 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 82 snlKQIDRIRTQLGMVFQNFNLWSHKTVLENI-IEAPVHVLKRPQAEcvehAEQLLEKVGLADKRHYYPAHLSGGQQQRA 160
Cdd:COG4133 68 ---DAREDYRRRLAYLGHADGLKPELTVRENLrFWAALYGLRADREA----IDEALEAVGLAGLADLPVRQLSAGQKRRV 140
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 497963481 161 AIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTH---EMDFAREVS 218
Cdd:COG4133 141 ALARLLLSPAPLWLLDEPFTALDAAGVALLAELIAAHLARGGAVLLTTHqplELAAARVLD 201
|
|
| LptB |
COG1137 |
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ... |
6-238 |
3.06e-38 |
|
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440752 [Multi-domain] Cd Length: 240 Bit Score: 133.62 E-value: 3.06e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEMKPnrkgqnrpsnlk 85
Cdd:COG1137 4 LEAENLVKSYGKRTVVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGEDITHLP------------ 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 86 qIDRiRTQLGM--------VFQNFnlwshkTVLENIIeAPVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQ 157
Cdd:COG1137 72 -MHK-RARLGIgylpqeasIFRKL------TVEDNIL-AVLELRKLSKKEREERLEELLEEFGITHLRKSKAYSLSGGER 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 158 QRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEmdfARE---VSNRIVFLHQGEIEEQGT 234
Cdd:COG1137 143 RRVEIARALATNPKFILLDEPFAGVDPIAVADIQKIIRHLKERGIGVLITDHN---VREtlgICDRAYIISEGKVLAEGT 219
|
....
gi 497963481 235 PEHV 238
Cdd:COG1137 220 PEEI 223
|
|
| PRK14239 |
PRK14239 |
phosphate transporter ATP-binding protein; Provisional |
1-239 |
5.24e-38 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 133.36 E-value: 5.24e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 1 MTTPAISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLE--LPdqgEIIVGGEAiemkpNRKGQ 78
Cdd:PRK14239 1 MTEPILQVSDLSVYYNKKKALNSVSLDFYPNEITALIGPSGSGKSTLLRSINRMNdlNP---EVTITGSI-----VYNGH 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 79 NRPSNLKQIDRIRTQLGMVFQNFNLWSHkTVLENII-------EAPVHVLKrpqaECVEHAEQ---LLEKVglADKRHYY 148
Cdd:PRK14239 73 NIYSPRTDTVDLRKEIGMVFQQPNPFPM-SIYENVVyglrlkgIKDKQVLD----EAVEKSLKgasIWDEV--KDRLHDS 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 149 PAHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEgMTMLVVTHEMDFAREVSNRIVFLHQGE 228
Cdd:PRK14239 146 ALGLSGGQQQRVCIARVLATSPKIILLDEPTSALDPISAGKIEETLLGLKDD-YTMLLVTRSMQQASRISDRTGFFLDGD 224
|
250
....*....|.
gi 497963481 229 IEEQGTPEHVF 239
Cdd:PRK14239 225 LIEYNDTKQMF 235
|
|
| TauB |
COG4525 |
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism]; |
4-246 |
7.86e-38 |
|
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443596 [Multi-domain] Cd Length: 262 Bit Score: 133.06 E-value: 7.86e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 4 PAISLRNIHKSFGSLD----VLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEmKPnrkGQN 79
Cdd:COG4525 2 SMLTVRHVSVRYPGGGqpqpALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEITLDGVPVT-GP---GAD 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 80 RpsnlkqidrirtqlGMVFQNFNLWSHKTVLENIiEAPVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQR 159
Cdd:COG4525 78 R--------------GVVFQKDALLPWLNVLDNV-AFGLRLRGVPKAERRARAEELLALVGLADFARRRIWQLSGGMRQR 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 160 AAIARALAMEPKVMLFDEPTSALDP---ELVGEVLrvMRTLADEGMTMLVVTHEMDFAREVSNRIVFL--HQGEIEEQGT 234
Cdd:COG4525 143 VGIARALAADPRFLLMDEPFGALDAltrEQMQELL--LDVWQRTGKGVFLITHSVEEALFLATRLVVMspGPGRIVERLE 220
|
250
....*....|....
gi 497963481 235 PE--HVFTASQSAR 246
Cdd:COG4525 221 LDfsRRFLAGEDAR 234
|
|
| nikE |
PRK10419 |
nickel ABC transporter ATP-binding protein NikE; |
16-245 |
9.05e-38 |
|
nickel ABC transporter ATP-binding protein NikE;
Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 133.27 E-value: 9.05e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 16 GSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEmKPNRKGQNRpsnlkqidrIRTQLG 95
Cdd:PRK10419 23 QHQTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEPLA-KLNRAQRKA---------FRRDIQ 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 96 MVFQN----FNlwSHKTVLENIIEAPVHVLKRPQAECVEHAEQLLEKVGL----ADKRhyyPAHLSGGQQQRAAIARALA 167
Cdd:PRK10419 93 MVFQDsisaVN--PRKTVREIIREPLRHLLSLDKAERLARASEMLRAVDLddsvLDKR---PPQLSGGQLQRVCLARALA 167
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 497963481 168 MEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVFTASQSA 245
Cdd:PRK10419 168 VEPKLLILDEAVSNLDLVLQAGVIRLLKKLQQQfGTACLFITHDLRLVERFCQRVMVMDNGQIVETQPVGDKLTFSSPA 246
|
|
| PRK09984 |
PRK09984 |
phosphonate ABC transporter ATP-binding protein; |
6-237 |
1.29e-37 |
|
phosphonate ABC transporter ATP-binding protein;
Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 132.83 E-value: 1.29e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQgeiiVGGEAIEMKpNRKGQNRPSNLK 85
Cdd:PRK09984 5 IRVEKLAKTFNQHQALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLITGDK----SAGSHIELL-GRTVQREGRLAR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 86 QIDRIRTQLGMVFQNFNLWSHKTVLENII----------EAPVHVLKRPQAEcveHAEQLLEKVGLADKRHYYPAHLSGG 155
Cdd:PRK09984 80 DIRKSRANTGYIFQQFNLVNRLSVLENVLigalgstpfwRTCFSWFTREQKQ---RALQALTRVGMVHFAHQRVSTLSGG 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 156 QQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTL-ADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGT 234
Cdd:PRK09984 157 QQQRVAIARALMQQAKVILADEPIASLDPESARIVMDTLRDInQNDGITVVVTLHQVDYALRYCERIVALRQGHVFYDGS 236
|
...
gi 497963481 235 PEH 237
Cdd:PRK09984 237 SQQ 239
|
|
| CeuD |
COG4604 |
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ... |
6-241 |
1.29e-37 |
|
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443654 [Multi-domain] Cd Length: 252 Bit Score: 132.51 E-value: 1.29e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRC-SNLLElPDQGEIIVGGEAIEMKPNRKGQNRPSNL 84
Cdd:COG4604 2 IEIKNVSKRYGGKVVLDDVSLTIPKGGITALIGPNGAGKSTLLSMiSRLLP-PDSGEVLVDGLDVATTPSRELAKRLAIL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 85 KQIDRIRTQLgmvfqnfnlwshkTVLEniieaPV------HVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQ 158
Cdd:COG4604 81 RQENHINSRL-------------TVRE-----LVafgrfpYSKGRLTAEDREIIDEAIAYLDLEDLADRYLDELSGGQRQ 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 159 RAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEH 237
Cdd:COG4604 143 RAFIAMVLAQDTDYVLLDEPLNNLDMKHSVQMMKLLRRLADElGKTVVIVLHDINFASCYADHIVAMKDGRVVAQGTPEE 222
|
....
gi 497963481 238 VFTA 241
Cdd:COG4604 223 IITP 226
|
|
| ABC_putative_ATPase |
cd03269 |
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ... |
6-233 |
1.68e-37 |
|
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 130.86 E-value: 1.68e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEmkpnrkgqnrpsnlk 85
Cdd:cd03269 1 LEVENVTKRFGRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPLD--------------- 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 86 qiDRIRTQLGMVFQNFNLWSHKTVLENIIE-APVHVLKRPQAEcvEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIAR 164
Cdd:cd03269 66 --IAARNRIGYLPEERGLYPKMKVIDQLVYlAQLKGLKKEEAR--RRIDEWLERLELSEYANKRVEELSKGNQQKVQFIA 141
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 497963481 165 ALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQG 233
Cdd:cd03269 142 AVIHDPELLILDEPFSGLDPVNVELLKDVIRELARAGKTVILSTHQMELVEELCDRVLLLNKGRAVLYG 210
|
|
| PRK11000 |
PRK11000 |
maltose/maltodextrin ABC transporter ATP-binding protein MalK; |
6-253 |
5.76e-37 |
|
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 133.62 E-value: 5.76e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAI-EMKPNRKGqnrpsnl 84
Cdd:PRK11000 4 VTLRNVTKAYGDVVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEKRMnDVPPAERG------- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 85 kqidrirtqLGMVFQNFNLWSHKTVLENiIEAPVHVLKRPQAEC---VEHAEQLLEKVGLADKRhyyPAHLSGGQQQRAA 161
Cdd:PRK11000 77 ---------VGMVFQSYALYPHLSVAEN-MSFGLKLAGAKKEEInqrVNQVAEVLQLAHLLDRK---PKALSGGQRQRVA 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 162 IARALAMEPKVMLFDEPTSALDPEL-VG---EVLRVMRTLadeGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEH 237
Cdd:PRK11000 144 IGRTLVAEPSVFLLDEPLSNLDAALrVQmriEISRLHKRL---GRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVGKPLE 220
|
250
....*....|....*..
gi 497963481 238 VFTASQSaRF-RQFIAS 253
Cdd:PRK11000 221 LYHYPAN-RFvAGFIGS 236
|
|
| ssuB |
PRK11247 |
aliphatic sulfonates transport ATP-binding subunit; Provisional |
3-229 |
1.25e-36 |
|
aliphatic sulfonates transport ATP-binding subunit; Provisional
Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 129.80 E-value: 1.25e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 3 TPaISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGgeaiemkpnrkgqNRPs 82
Cdd:PRK11247 11 TP-LLLNAVSKRYGERTVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGELLAG-------------TAP- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 83 nlkqIDRIRTQLGMVFQNFNLWSHKTVLENIIEApvhvLK---RPQAEcvehaeQLLEKVGLADKRHYYPAHLSGGQQQR 159
Cdd:PRK11247 76 ----LAEAREDTRLMFQDARLLPWKKVIDNVGLG----LKgqwRDAAL------QALAAVGLADRANEWPAALSGGQKQR 141
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 497963481 160 AAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQGEI 229
Cdd:PRK11247 142 VALARALIHRPGLLLLDEPLGALDALTRIEMQDLIESLWQQhGFTVLLVTHDVSEAVAMADRVLLIEEGKI 212
|
|
| YhaQ |
COG4152 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
5-238 |
1.44e-36 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 131.00 E-value: 1.44e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 5 AISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGeaiemkpnrkgqnRPSNL 84
Cdd:COG4152 1 MLELKGLTKRFGDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDG-------------EPLDP 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 85 KQIDRI------RtqlGmvfqnfnLWSHKTVLENIIE-APVHVLKRPQAEcvEHAEQLLEKVGLADKRHyypaH----LS 153
Cdd:COG4152 68 EDRRRIgylpeeR---G-------LYPKMKVGEQLVYlARLKGLSKAEAK--RRADEWLERLGLGDRAN----KkveeLS 131
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 154 GGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQG 233
Cdd:COG4152 132 KGNQQKVQLIAALLHDPELLILDEPFSGLDPVNVELLKDVIRELAAKGTTVIFSSHQMELVEELCDRIVIINKGRKVLSG 211
|
....*
gi 497963481 234 TPEHV 238
Cdd:COG4152 212 SVDEI 216
|
|
| lolD |
PRK11629 |
lipoprotein-releasing ABC transporter ATP-binding protein LolD; |
1-234 |
2.08e-36 |
|
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 128.78 E-value: 2.08e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 1 MTTPAISLRNIHKSF--GSL--DVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIemkpnrk 76
Cdd:PRK11629 1 MNKILLQCDNLCKRYqeGSVqtDVLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPM------- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 77 gqNRPSNLKQIDRIRTQLGMVFQNFNLWSHKTVLENIiEAPVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQ 156
Cdd:PRK11629 74 --SKLSSAAKAELRNQKLGFIYQFHHLLPDFTALENV-AMPLLIGKKKPAEINSRALEMLAAVGLEHRANHRPSELSGGE 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 157 QQRAAIARALAMEPKVMLFDEPTSALDP-------ELVGEVLRvmrtlaDEGMTMLVVTHEMDFAREVSnRIVFLHQGEI 229
Cdd:PRK11629 151 RQRVAIARALVNNPRLVLADEPTGNLDArnadsifQLLGELNR------LQGTAFLVVTHDLQLAKRMS-RQLEMRDGRL 223
|
....*
gi 497963481 230 EEQGT 234
Cdd:PRK11629 224 TAELS 228
|
|
| SapF |
COG4167 |
ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms]; |
3-253 |
2.96e-36 |
|
ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];
Pssm-ID: 443328 [Multi-domain] Cd Length: 265 Bit Score: 129.19 E-value: 2.96e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 3 TPAISLRNIHKSF---------GSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEmkp 73
Cdd:COG4167 2 SALLEVRNLSKTFkyrtglfrrQQFEAVKPVSFTLEAGQTLAIIGENGSGKSTLAKMLAGIIEPTSGEILINGHKLE--- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 74 nrkgqnrPSNLKQidriRTQL-GMVFQNFN--LWSHKTVLEnIIEAPvhvLKR----PQAECVEHAEQLLEKVGL-ADKR 145
Cdd:COG4167 79 -------YGDYKY----RCKHiRMIFQDPNtsLNPRLNIGQ-ILEEP---LRLntdlTAEEREERIFATLRLVGLlPEHA 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 146 HYYPAHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFL 224
Cdd:COG4167 144 NFYPHMLSSGQKQRVALARALILQPKIIIADEALAALDMSVRSQIINLMLELQEKlGISYIYVSQHLGIVKHISDKVLVM 223
|
250 260
....*....|....*....|....*....
gi 497963481 225 HQGEIEEQGTPEHVFTASQSARFRQFIAS 253
Cdd:COG4167 224 HQGEVVEYGKTAEVFANPQHEVTKRLIES 252
|
|
| thiQ |
TIGR01277 |
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ... |
25-233 |
3.29e-36 |
|
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]
Pssm-ID: 130344 [Multi-domain] Cd Length: 213 Bit Score: 127.67 E-value: 3.29e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 25 SIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEMKPNRKgqnRPsnlkqidrirtqLGMVFQNFNLW 104
Cdd:TIGR01277 18 DLNVADGEIVAIMGPSGAGKSTLLNLIAGFIEPASGSIKVNDQSHTGLAPYQ---RP------------VSMLFQENNLF 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 105 SHKTVLENIiEAPVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDP 184
Cdd:TIGR01277 83 AHLTVRQNI-GLGLHPGLKLNAEQQEKVVDAAQQVGIADYLDRLPEQLSGGQRQRVALARCLVRPNPILLLDEPFSALDP 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 497963481 185 ELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQG 233
Cdd:TIGR01277 162 LLREEMLALVKQLCSErQRTLLMVTHHLSDARAIASQIAVVSQGKIKVVS 211
|
|
| ABC_drug_resistance_like |
cd03264 |
ABC-type multidrug transport system, ATPase component; The biological function of this family ... |
6-233 |
5.96e-36 |
|
ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 126.92 E-value: 5.96e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLDVLKGISIEANQGeVISILGSSGSGKSTLLR-CSNLLElPDQGEIIVGGEAIemkpnrkgqnrpsnL 84
Cdd:cd03264 1 LQLENLTKRYGKKRALDGVSLTLGPG-MYGLLGPNGAGKTTLMRiLATLTP-PSSGTIRIDGQDV--------------L 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 85 KQIDRIRTQLGMVFQNFNLWSHKTVLENIieAPVHVLKR-PQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIA 163
Cdd:cd03264 65 KQPQKLRRRIGYLPQEFGVYPNFTVREFL--DYIAWLKGiPSKEVKARVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIA 142
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 497963481 164 RALAMEPKVMLFDEPTSALDPElvgEVLRVMRTLAD--EGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQG 233
Cdd:cd03264 143 QALVGDPSILIVDEPTAGLDPE---ERIRFRNLLSElgEDRIVILSTHIVEDVESLCNQVAVLNKGKLVFEG 211
|
|
| ABC_NatA_sodium_exporter |
cd03266 |
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ... |
6-233 |
6.29e-36 |
|
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.
Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 127.10 E-value: 6.29e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLD----VLKGISIEANQGEVISILGSSGSGKSTLLR-CSNLLElPDQGEIIVGGEAIEMKPNRkgqnr 80
Cdd:cd03266 2 ITADALTKRFRDVKktvqAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRmLAGLLE-PDAGFATVDGFDVVKEPAE----- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 81 psnlkqidrIRTQLGMVFQNFNLWSHKTVLENIIE-APVHVLKRPQAEC-VEHAEQLLEKVGLADKRhyyPAHLSGGQQQ 158
Cdd:cd03266 76 ---------ARRRLGFVSDSTGLYDRLTARENLEYfAGLYGLKGDELTArLEELADRLGMEELLDRR---VGGFSTGMRQ 143
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 497963481 159 RAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQG 233
Cdd:cd03266 144 KVAIARALVHDPPVLLLDEPTTGLDVMATRALREFIRQLRALGKCILFSTHIMQEVERLCDRVVVLHRGRVVYEG 218
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
20-252 |
8.54e-36 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 133.29 E-value: 8.54e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 20 VLKGISIEANQGEVISILGSSGSGKST----LLRCsnlleLPDQGEIIVGGEAIEmkpnrkGQNRpsnlKQIDRIRTQLG 95
Cdd:PRK15134 301 VVKNISFTLRPGETLGLVGESGSGKSTtglaLLRL-----INSQGEIWFDGQPLH------NLNR----RQLLPVRHRIQ 365
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 96 MVFQNFN--LWSHKTVLENIIEA-PVHVLKRPQAECVEHAEQLLEKVGL-ADKRHYYPAHLSGGQQQRAAIARALAMEPK 171
Cdd:PRK15134 366 VVFQDPNssLNPRLNVLQIIEEGlRVHQPTLSAAQREQQVIAVMEEVGLdPETRHRYPAEFSGGQRQRIAIARALILKPS 445
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 172 VMLFDEPTSALDPELVGEVLRVMRTL-ADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVFTASQSARFRQF 250
Cdd:PRK15134 446 LIILDEPTSSLDKTVQAQILALLKSLqQKHQLAYLFISHDLHVVRALCHQVIVLRQGEVVEQGDCERVFAAPQQEYTRQL 525
|
..
gi 497963481 251 IA 252
Cdd:PRK15134 526 LA 527
|
|
| PRK10908 |
PRK10908 |
cell division ATP-binding protein FtsE; |
6-229 |
1.16e-35 |
|
cell division ATP-binding protein FtsE;
Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 126.53 E-value: 1.16e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSF-GSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEMKPNRkgqnrpsnl 84
Cdd:PRK10908 2 IRFEHVSKAYlGGRQALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITRLKNR--------- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 85 kQIDRIRTQLGMVFQNFNLWSHKTVLENIiEAPVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIAR 164
Cdd:PRK10908 73 -EVPFLRRQIGMIFQDHHLLMDRTVYDNV-AIPLIIAGASGDDIRRRVSAALDKVGLLDKAKNFPIQLSGGEQQRVGIAR 150
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 497963481 165 ALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEI 229
Cdd:PRK10908 151 AVVNKPAVLLADEPTGNLDDALSEGILRLFEEFNRVGVTVLMATHDIGLISRRSYRMLTLSDGHL 215
|
|
| livG |
PRK11300 |
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional |
1-238 |
1.21e-35 |
|
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
Pssm-ID: 183080 [Multi-domain] Cd Length: 255 Bit Score: 127.41 E-value: 1.21e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 1 MTTPAISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEMKPnrkGQnr 80
Cdd:PRK11300 1 MSQPLLSVSGLMMRFGGLLAVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQHIEGLP---GH-- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 81 psnlkQIDRirtqLGMV--FQNFNLWSHKTVLENIIEAPVHVLK--------------RPQAECVEHAEQLLEKVGLADK 144
Cdd:PRK11300 76 -----QIAR----MGVVrtFQHVRLFREMTVIENLLVAQHQQLKtglfsgllktpafrRAESEALDRAATWLERVGLLEH 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 145 RHYYPAHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVF 223
Cdd:PRK11300 147 ANRQAGNLAYGQQRRLEIARCMVTQPEILMLDEPAAGLNPKETKELDELIAELRNEhNVTVLLIEHDMKLVMGISDRIYV 226
|
250
....*....|....*
gi 497963481 224 LHQGEIEEQGTPEHV 238
Cdd:PRK11300 227 VNQGTPLANGTPEEI 241
|
|
| cbiO |
PRK13649 |
energy-coupling factor transporter ATPase; |
21-239 |
5.61e-35 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184208 [Multi-domain] Cd Length: 280 Bit Score: 126.40 E-value: 5.61e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 21 LKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIemkpnrkgqNRPSNLKQIDRIRTQLGMVFQn 100
Cdd:PRK13649 23 LFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLI---------TSTSKNKDIKQIRKKVGLVFQ- 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 101 F--NLWSHKTVLENIIEAPVHvLKRPQAECVEHAEQLLEKVGLADK-RHYYPAHLSGGQQQRAAIARALAMEPKVMLFDE 177
Cdd:PRK13649 93 FpeSQLFEETVLKDVAFGPQN-FGVSQEEAEALAREKLALVGISESlFEKNPFELSGGQMRRVAIAGILAMEPKILVLDE 171
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 497963481 178 PTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVF 239
Cdd:PRK13649 172 PTAGLDPKGRKELMTLFKKLHQSGMTIVLVTHLMDDVANYADFVYVLEKGKLVLSGKPKDIF 233
|
|
| cbiO |
PRK13644 |
energy-coupling factor transporter ATPase; |
6-240 |
6.38e-35 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 125.87 E-value: 6.38e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSF-GSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGeaiemkpnrKGQNRPSNL 84
Cdd:PRK13644 2 IRLENVSYSYpDGTPALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSG---------IDTGDFSKL 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 85 KQIDRIrtqLGMVFQNFNL-WSHKTVLENIIEAPVHvLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIA 163
Cdd:PRK13644 73 QGIRKL---VGIVFQNPETqFVGRTVEEDLAFGPEN-LCLPPIEIRKRVDRALAEIGLEKYRHRSPKTLSGGQGQCVALA 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 497963481 164 RALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDfAREVSNRIVFLHQGEIEEQGTPEHVFT 240
Cdd:PRK13644 149 GILTMEPECLIFDEVTSMLDPDSGIAVLERIKKLHEKGKTIVYITHNLE-ELHDADRIIVMDRGKIVLEGEPENVLS 224
|
|
| PRK10070 |
PRK10070 |
proline/glycine betaine ABC transporter ATP-binding protein ProV; |
21-250 |
2.01e-34 |
|
proline/glycine betaine ABC transporter ATP-binding protein ProV;
Pssm-ID: 182221 [Multi-domain] Cd Length: 400 Bit Score: 127.46 E-value: 2.01e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 21 LKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIemkpnrkGQNRPSNLKQIDRirTQLGMVFQN 100
Cdd:PRK10070 44 VKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDI-------AKISDAELREVRR--KKIAMVFQS 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 101 FNLWSHKTVLENIIEApVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIARALAMEPKVMLFDEPTS 180
Cdd:PRK10070 115 FALMPHMTVLDNTAFG-MELAGINAEERREKALDALRQVGLENYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFS 193
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 497963481 181 ALDPELVGEVL-RVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVFTASQSARFRQF 250
Cdd:PRK10070 194 ALDPLIRTEMQdELVKLQAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEILNNPANDYVRTF 264
|
|
| PhnK |
COG1101 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
6-229 |
2.53e-34 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 440718 [Multi-domain] Cd Length: 264 Bit Score: 124.04 E-value: 2.53e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSF--GSLD---VLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIemkpnrkgqnr 80
Cdd:COG1101 2 LELKNLSKTFnpGTVNekrALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGKDV----------- 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 81 pSNLKQIDRIRtQLGMVFQN------FNLwshkTVLENIIEApvhvLKRPQ---------AECVEHAEQLLEKVGLA-DK 144
Cdd:COG1101 71 -TKLPEYKRAK-YIGRVFQDpmmgtaPSM----TIEENLALA----YRRGKrrglrrgltKKRRELFRELLATLGLGlEN 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 145 RHYYPA-HLSGGQQQraaiARALAM----EPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVS 218
Cdd:COG1101 141 RLDTKVgLLSGGQRQ----ALSLLMatltKPKLLLLDEHTAALDPKTAALVLELTEKIVEEnNLTTLMVTHNMEQALDYG 216
|
250
....*....|.
gi 497963481 219 NRIVFLHQGEI 229
Cdd:COG1101 217 NRLIMMHEGRI 227
|
|
| cbiO |
PRK13641 |
energy-coupling factor transporter ATPase; |
21-240 |
3.20e-34 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 124.56 E-value: 3.20e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 21 LKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEMKPNRKgqnrpsNLKqidRIRTQLGMVFQn 100
Cdd:PRK13641 23 LDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHITPETGNK------NLK---KLRKKVSLVFQ- 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 101 F--NLWSHKTVLENIIEAPVHvLKRPQAECVEHAEQLLEKVGLADK-RHYYPAHLSGGQQQRAAIARALAMEPKVMLFDE 177
Cdd:PRK13641 93 FpeAQLFENTVLKDVEFGPKN-FGFSEDEAKEKALKWLKKVGLSEDlISKSPFELSGGQMRRVAIAGVMAYEPEILCLDE 171
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 497963481 178 PTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVFT 240
Cdd:PRK13641 172 PAAGLDPEGRKEMMQLFKDYQKAGHTVILVTHNMDDVAEYADDVLVLEHGKLIKHASPKEIFS 234
|
|
| thiQ |
PRK10771 |
thiamine ABC transporter ATP-binding protein ThiQ; |
25-245 |
3.84e-34 |
|
thiamine ABC transporter ATP-binding protein ThiQ;
Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 122.77 E-value: 3.84e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 25 SIEANQGEVISILGSSGSGKSTLLrcsNLLE---LPDQGEIIVGGEAIEMKPNRKgqnRPsnlkqidrirtqLGMVFQNF 101
Cdd:PRK10771 19 DLTVERGERVAILGPSGAGKSTLL---NLIAgflTPASGSLTLNGQDHTTTPPSR---RP------------VSMLFQEN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 102 NLWSHKTVLENIiEAPVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIARALAMEPKVMLFDEPTSA 181
Cdd:PRK10771 81 NLFSHLTVAQNI-GLGLNPGLKLNAAQREKLHAIARQMGIEDLLARLPGQLSGGQRQRVALARCLVREQPILLLDEPFSA 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 497963481 182 LDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVFTASQSA 245
Cdd:PRK10771 160 LDPALRQEMLTLVSQVCQErQLTLLMVSHSLEDAARIAPRSLVVADGRIAWDGPTDELLSGKASA 224
|
|
| dppF |
PRK11308 |
dipeptide transporter ATP-binding subunit; Provisional |
1-240 |
6.36e-34 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 236898 [Multi-domain] Cd Length: 327 Bit Score: 124.69 E-value: 6.36e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 1 MTTPAISLRNIHKSF----------GSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIe 70
Cdd:PRK11308 1 SQQPLLQAIDLKKHYpvkrglfkpeRLVKALDGVSFTLERGKTLAVVGESGCGKSTLARLLTMIETPTGGELYYQGQDL- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 71 MKPNRKGQNRpsnlkqidrIRTQLGMVFQN--FNLWSHKTVlENIIEAPVHV-LKRPQAECVEHAEQLLEKVGLADKrHY 147
Cdd:PRK11308 80 LKADPEAQKL---------LRQKIQIVFQNpyGSLNPRKKV-GQILEEPLLInTSLSAAERREKALAMMAKVGLRPE-HY 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 148 --YPAHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFL 224
Cdd:PRK11308 149 drYPHMFSGGQRQRIAIARALMLDPDVVVADEPVSALDVSVQAQVLNLMMDLQQElGLSYVFISHDLSVVEHIADEVMVM 228
|
250
....*....|....*.
gi 497963481 225 HQGEIEEQGTPEHVFT 240
Cdd:PRK11308 229 YLGRCVEKGTKEQIFN 244
|
|
| cbiO |
PRK13640 |
energy-coupling factor transporter ATPase; |
1-239 |
8.40e-34 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 123.37 E-value: 8.40e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 1 MTTPAISLRniHKSFGSLD----VLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPD---QGEIIVGGEAIemkp 73
Cdd:PRK13640 1 MKDNIVEFK--HVSFTYPDskkpALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLLPDdnpNSKITVDGITL---- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 74 nrkgqnrpsNLKQIDRIRTQLGMVFQN-FNLWSHKTV-------LENiieapvhvLKRPQAECVEHAEQLLEKVGLADKR 145
Cdd:PRK13640 75 ---------TAKTVWDIREKVGIVFQNpDNQFVGATVgddvafgLEN--------RAVPRPEMIKIVRDVLADVGMLDYI 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 146 HYYPAHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLA-DEGMTMLVVTHEMDFArEVSNRIVFL 224
Cdd:PRK13640 138 DSEPANLSGGQKQRVAIAGILAVEPKIIILDESTSMLDPAGKEQILKLIRKLKkKNNLTVISITHDIDEA-NMADQVLVL 216
|
250
....*....|....*
gi 497963481 225 HQGEIEEQGTPEHVF 239
Cdd:PRK13640 217 DDGKLLAQGSPVEIF 231
|
|
| PRK14271 |
PRK14271 |
phosphate ABC transporter ATP-binding protein; Provisional |
4-252 |
9.83e-34 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172759 [Multi-domain] Cd Length: 276 Bit Score: 122.90 E-value: 9.83e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 4 PAISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLE-----LPDQGEIIVGGEAIemkpnrkgq 78
Cdd:PRK14271 20 PAMAAVNLTLGFAGKTVLDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRMNdkvsgYRYSGDVLLGGRSI--------- 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 79 nrpSNLKQIDRIRTQLGMVFQNFNLWShKTVLENIIeAPVHVLKR-PQAECVEHAEQLLEKVGL----ADKRHYYPAHLS 153
Cdd:PRK14271 91 ---FNYRDVLEFRRRVGMLFQRPNPFP-MSIMDNVL-AGVRAHKLvPRKEFRGVAQARLTEVGLwdavKDRLSDSPFRLS 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 154 GGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEgMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQG 233
Cdd:PRK14271 166 GGQQQLLCLARTLAVNPEVLLLDEPTSALDPTTTEKIEEFIRSLADR-LTVIIVTHNLAQAARISDRAALFFDGRLVEEG 244
|
250
....*....|....*....
gi 497963481 234 TPEHVFTASQSARFRQFIA 252
Cdd:PRK14271 245 PTEQLFSSPKHAETARYVA 263
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
4-238 |
1.48e-33 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 126.84 E-value: 1.48e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 4 PAISLRNIHKSFGSLD--VLK---GISIEANQGEVISILGSSGSGKSTLLRC-SNLLElPDQGE--IIVGGEAIEM-KPN 74
Cdd:TIGR03269 278 PIIKVRNVSKRYISVDrgVVKavdNVSLEVKEGEIFGIVGTSGAGKTTLSKIiAGVLE-PTSGEvnVRVGDEWVDMtKPG 356
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 75 RKGQNRpsnlkqidrIRTQLGMVFQNFNLWSHKTVLENIIEA-------------PVHVLKRPQAEcVEHAEQLLEKvgl 141
Cdd:TIGR03269 357 PDGRGR---------AKRYIGILHQEYDLYPHRTVLDNLTEAiglelpdelarmkAVITLKMVGFD-EEKAEEILDK--- 423
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 142 adkrhyYPAHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLR-VMRTLADEGMTMLVVTHEMDFAREVSNR 220
Cdd:TIGR03269 424 ------YPDELSEGERHRVALAQVLIKEPRIVILDEPTGTMDPITKVDVTHsILKAREEMEQTFIIVSHDMDFVLDVCDR 497
|
250
....*....|....*...
gi 497963481 221 IVFLHQGEIEEQGTPEHV 238
Cdd:TIGR03269 498 AALMRDGKIVKIGDPEEI 515
|
|
| YnjD |
COG4136 |
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ... |
7-223 |
1.57e-33 |
|
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];
Pssm-ID: 443311 [Multi-domain] Cd Length: 211 Bit Score: 120.66 E-value: 1.57e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 7 SLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLrcSNLL-ELPD----QGEIIVGGEAIEMKPNRkgqnrp 81
Cdd:COG4136 3 SLENLTITLGGRPLLAPLSLTVAPGEILTLMGPSGSGKSTLL--AAIAgTLSPafsaSGEVLLNGRRLTALPAE------ 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 82 snlkqidriRTQLGMVFQNFNLWSHKTVLENIIEAPVHVLKRPQAEcvEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAA 161
Cdd:COG4136 75 ---------QRRIGILFQDDLLFPHLSVGENLAFALPPTIGRAQRR--ARVEQALEEAGLAGFADRDPATLSGGQRARVA 143
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 497963481 162 IARALAMEPKVMLFDEPTSALDPELVGEVLR-VMRTLADEGMTMLVVTHEMDFAREVSNRIVF 223
Cdd:COG4136 144 LLRALLAEPRALLLDEPFSKLDAALRAQFREfVFEQIRQRGIPALLVTHDEEDAPAAGRVLDL 206
|
|
| cbiO |
PRK13645 |
energy-coupling factor transporter ATPase; |
21-240 |
3.05e-33 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 122.04 E-value: 3.05e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 21 LKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIemkpnrkgqnrPSNLKQID---RIRTQLGMV 97
Cdd:PRK13645 27 LNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQTIVGDYAI-----------PANLKKIKevkRLRKEIGLV 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 98 FQ--NFNLWsHKTVLENIIEAPVHvLKRPQAECVEHAEQLLEKVGLAD---KRHyyPAHLSGGQQQRAAIARALAMEPKV 172
Cdd:PRK13645 96 FQfpEYQLF-QETIEKDIAFGPVN-LGENKQEAYKKVPELLKLVQLPEdyvKRS--PFELSGGQKRRVALAGIIAMDGNT 171
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 497963481 173 MLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVFT 240
Cdd:PRK13645 172 LVLDEPTGGLDPKGEEDFINLFERLNKEyKKRIIMVTHNMDQVLRIADEVIVMHEGKVISIGSPFEIFS 240
|
|
| cbiO |
PRK13643 |
energy-coupling factor transporter ATPase; |
24-239 |
4.08e-33 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 121.76 E-value: 4.08e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 24 ISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIemkpnrkgqNRPSNLKQIDRIRTQLGMVFQ--NF 101
Cdd:PRK13643 25 IDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVGDIVV---------SSTSKQKEIKPVRKKVGVVFQfpES 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 102 NLWsHKTVLENIIEAPVHV-LKRPQAECVehAEQLLEKVGLADK-RHYYPAHLSGGQQQRAAIARALAMEPKVMLFDEPT 179
Cdd:PRK13643 96 QLF-EETVLKDVAFGPQNFgIPKEKAEKI--AAEKLEMVGLADEfWEKSPFELSGGQMRRVAIAGILAMEPEVLVLDEPT 172
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 180 SALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVF 239
Cdd:PRK13643 173 AGLDPKARIEMMQLFESIHQSGQTVVLVTHLMDDVADYADYVYLLEKGHIISCGTPSDVF 232
|
|
| PhnL |
COG4778 |
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ... |
1-224 |
4.33e-33 |
|
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];
Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 119.85 E-value: 4.33e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 1 MTTpAISLRNIHKSF-----GS--LDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIV--GGEAIEM 71
Cdd:COG4778 1 MTT-LLEVENLSKTFtlhlqGGkrLPVLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILVrhDGGWVDL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 72 KpnrKGQNRpsnlkQIDRIR-TQLGMVFQNFNLWSHKTVLEnIIEAPVHVLKRPQAECVEHAEQLLEKVGLADKR-HYYP 149
Cdd:COG4778 80 A---QASPR-----EILALRrRTIGYVSQFLRVIPRVSALD-VVAEPLLERGVDREEARARARELLARLNLPERLwDLPP 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 497963481 150 AHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFL 224
Cdd:COG4778 151 ATFSGGEQQRVNIARGFIADPPLLLLDEPTASLDAANRAVVVELIEEAKARGTAIIGIFHDEEVREAVADRVVDV 225
|
|
| cbiO |
PRK13648 |
cobalt transporter ATP-binding subunit; Provisional |
21-244 |
4.99e-33 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 121.01 E-value: 4.99e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 21 LKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVggeaiemkpnrkgQNRPSNLKQIDRIRTQLGMVFQN 100
Cdd:PRK13648 25 LKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFY-------------NNQAITDDNFEKLRKHIGIVFQN 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 101 -FNLWSHKTV-------LENiieapvHVLkrPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIARALAMEPKV 172
Cdd:PRK13648 92 pDNQFVGSIVkydvafgLEN------HAV--PYDEMHRRVSEALKQVDMLERADYEPNALSGGQKQRVAIAGVLALNPSV 163
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 497963481 173 MLFDEPTSALDPELVGEVLRVMRTL-ADEGMTMLVVTHEMDFAREvSNRIVFLHQGEIEEQGTPEHVFTASQS 244
Cdd:PRK13648 164 IILDEATSMLDPDARQNLLDLVRKVkSEHNITIISITHDLSEAME-ADHVIVMNKGTVYKEGTPTEIFDHAEE 235
|
|
| modC_ABC |
TIGR02142 |
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ... |
32-238 |
6.53e-33 |
|
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]
Pssm-ID: 131197 [Multi-domain] Cd Length: 354 Bit Score: 122.53 E-value: 6.53e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 32 EVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAieMKPNRKGQNRPSNlkqidriRTQLGMVFQNFNLWSHKTVLE 111
Cdd:TIGR02142 24 GVTAIFGRSGSGKTTLIRLIAGLTRPDEGEIVLNGRT--LFDSRKGIFLPPE-------KRRIGYVFQEARLFPHLSVRG 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 112 NIieapVHVLKRPQAECVEHA-EQLLEKVGLADKRHYYPAHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEV 190
Cdd:TIGR02142 95 NL----RYGMKRARPSERRISfERVIELLGIGHLLGRLPGRLSGGEKQRVAIGRALLSSPRLLLMDEPLAALDDPRKYEI 170
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 497963481 191 LRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHV 238
Cdd:TIGR02142 171 LPYLERLHAEfGIPILYVSHSLQEVLRLADRVVVLEDGRVAAAGPIAEV 219
|
|
| PRK14246 |
PRK14246 |
phosphate ABC transporter ATP-binding protein; Provisional |
20-251 |
7.66e-33 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 120.15 E-value: 7.66e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 20 VLKGISIEANQGEVISILGSSGSGKSTLLRCSN-LLELPDQgEIIVGGEAIEMKpnrkgqnrpSNLKQID--RIRTQLGM 96
Cdd:PRK14246 25 ILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNrLIEIYDS-KIKVDGKVLYFG---------KDIFQIDaiKLRKEVGM 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 97 VFQNFNLWSHKTVLENIIEAPVHVLKRPQAECVEHAEQLLEKVGL----ADKRHYYPAHLSGGQQQRAAIARALAMEPKV 172
Cdd:PRK14246 95 VFQQPNPFPHLSIYDNIAYPLKSHGIKEKREIKKIVEECLRKVGLwkevYDRLNSPASQLSGGQQQRLTIARALALKPKV 174
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 497963481 173 MLFDEPTSALDPELVGEVLRVMRTLADEgMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVFTASQSARFRQFI 251
Cdd:PRK14246 175 LLMDEPTSMIDIVNSQAIEKLITELKNE-IAIVIVSHNPQQVARVADYVAFLYNGELVEWGSSNEIFTSPKNELTEKYV 252
|
|
| NHLM_micro_ABC2 |
TIGR03797 |
NHLM bacteriocin system ABC transporter, ATP-binding protein; Members of this protein family ... |
20-236 |
7.82e-33 |
|
NHLM bacteriocin system ABC transporter, ATP-binding protein; Members of this protein family are ABC transporter ATP-binding subunits, part of a three-gene putative bacteriocin transport operon. The other subunits include another ATP-binding subunit (TIGR03796), which has an N-terminal leader sequence cleavage domain, and an HlyD homolog (TIGR03794). In a number of genomes, members of protein families related to nitrile hydratase alpha subunit or to nif11 have undergone paralogous family expansions, with members possessing a putative bacteriocin cleavage region ending with a classic Gly-Gly motif. Those sets of putative bacteriocins, members of this protein family and its partners TIGR03794 and TIGR03796, and cyclodehydratase/docking scaffold fusion proteins of thiazole/oxazole biosynthesis frequently show correlated species distribution and co-clustering within many of those genomes. [Transport and binding proteins, Amino acids, peptides and amines, Cellular processes, Biosynthesis of natural products]
Pssm-ID: 274789 [Multi-domain] Cd Length: 686 Bit Score: 125.84 E-value: 7.82e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 20 VLKGISIEANQGEVISILGSSGSGKSTLLRcsnLL---ELPDQGEIIVGGEAIemkpnrKGQNrpsnlkqIDRIRTQLGM 96
Cdd:TIGR03797 468 ILDDVSLQIEPGEFVAIVGPSGSGKSTLLR---LLlgfETPESGSVFYDGQDL------AGLD-------VQAVRRQLGV 531
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 97 VFQNFNLWShKTVLENII-EAPVhvlkrpqaeCVEHAEQLLEKVGLADKRHYYP-----------AHLSGGQQQRAAIAR 164
Cdd:TIGR03797 532 VLQNGRLMS-GSIFENIAgGAPL---------TLDEAWEAARMAGLAEDIRAMPmgmhtviseggGTLSGGQRQRLLIAR 601
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 497963481 165 ALAMEPKVMLFDEPTSALDPELVGevlRVMRTLADEGMTMLVVTHEMDFAREvSNRIVFLHQGEIEEQGTPE 236
Cdd:TIGR03797 602 ALVRKPRILLFDEATSALDNRTQA---IVSESLERLKVTRIVIAHRLSTIRN-ADRIYVLDAGRVVQQGTYD 669
|
|
| btuD |
PRK09536 |
corrinoid ABC transporter ATPase; Reviewed |
4-241 |
1.11e-32 |
|
corrinoid ABC transporter ATPase; Reviewed
Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 123.03 E-value: 1.11e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 4 PAISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEMKPNRKGQNRPSN 83
Cdd:PRK09536 2 PMIDVSDLSVEFGDTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDVEALSARAASRRVAS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 84 LKQidriRTQLGMVFQnfnlwshktvLENIIEAPVHV-LKR--PQAECVEHA-EQLLEKVGLADKRHYYPAHLSGGQQQR 159
Cdd:PRK09536 82 VPQ----DTSLSFEFD----------VRQVVEMGRTPhRSRfdTWTETDRAAvERAMERTGVAQFADRPVTSLSGGERQR 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 160 AAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVF 239
Cdd:PRK09536 148 VLLARALAQATPVLLLDEPTASLDINHQVRTLELVRRLVDDGKTAVAAIHDLDLAARYCDELVLLADGRVRAAGPPADVL 227
|
..
gi 497963481 240 TA 241
Cdd:PRK09536 228 TA 229
|
|
| ABC_BcrA_bacitracin_resist |
cd03268 |
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ... |
6-233 |
1.24e-32 |
|
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.
Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 118.09 E-value: 1.24e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIemkpnrkgQNRPSNLK 85
Cdd:cd03268 1 LKTNDLTKTYGKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGKSY--------QKNIEALR 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 86 QIdrirtqlGMVFQNFNLWSHKTVLENIIEAPVhVLKRPQAECvehaEQLLEKVGLADKRHYYPAHLSGGQQQRAAIARA 165
Cdd:cd03268 73 RI-------GALIEAPGFYPNLTARENLRLLAR-LLGIRKKRI----DEVLDVVGLKDSAKKKVKGFSLGMKQRLGIALA 140
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 497963481 166 LAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQG 233
Cdd:cd03268 141 LLGNPDLLILDEPTNGLDPDGIKELRELILSLRDQGITVLISSHLLSEIQKVADRIGIINKGKLIEEG 208
|
|
| phnK |
PRK11701 |
phosphonate C-P lyase system protein PhnK; Provisional |
1-240 |
2.10e-32 |
|
phosphonate C-P lyase system protein PhnK; Provisional
Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 118.88 E-value: 2.10e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 1 MTTPAISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGeaiemkpnRKGQNR 80
Cdd:PRK11701 2 MDQPLLSVRGLTKLYGPRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVHYRM--------RDGQLR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 81 P-SNLKQIDR---IRTQLGMVFQN--FNLWSHKTVLENIIEAPVHVLKRPQAECVEHAEQLLEKVGLADKR-HYYPAHLS 153
Cdd:PRK11701 74 DlYALSEAERrrlLRTEWGFVHQHprDGLRMQVSAGGNIGERLMAVGARHYGDIRATAGDWLERVEIDAARiDDLPTTFS 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 154 GGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQ 232
Cdd:PRK11701 154 GGMQQRLQIARNLVTHPRLVFMDEPTGGLDVSVQARLLDLLRGLVRElGLAVVIVTHDLAVARLLAHRLLVMKQGRVVES 233
|
250
....*....|....*
gi 497963481 233 G-------TPEHVFT 240
Cdd:PRK11701 234 GltdqvldDPQHPYT 248
|
|
| ABCC_Hemolysin |
cd03252 |
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ... |
6-236 |
3.26e-32 |
|
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.
Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 117.97 E-value: 3.26e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFG--SLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGeaiemkpnrkgqnrpSN 83
Cdd:cd03252 1 ITFEHVRFRYKpdGPVILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDG---------------HD 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 84 LKQIDR--IRTQLGMVFQNfNLWSHKTVLENIieapvhVLKRPQAEcvehAEQLLEKVGLADKRHYYP------------ 149
Cdd:cd03252 66 LALADPawLRRQVGVVLQE-NVLFNRSIRDNI------ALADPGMS----MERVIEAAKLAGAHDFISelpegydtivge 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 150 --AHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADeGMTMLVVTHEMDFAREvSNRIVFLHQG 227
Cdd:cd03252 135 qgAGLSGGQRQRIAIARALIHNPRILIFDEATSALDYESEHAIMRNMHDICA-GRTVIIIAHRLSTVKN-ADRIIVMEKG 212
|
....*....
gi 497963481 228 EIEEQGTPE 236
Cdd:cd03252 213 RIVEQGSHD 221
|
|
| ABCC_ATM1_transporter |
cd03253 |
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ... |
6-236 |
4.76e-32 |
|
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 117.33 E-value: 4.76e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFG-SLDVLKGISIEANQGEVISILGSSGSGKSTLLRCsnLLEL--PDQGEIIVGGEAIemkpnrkgqnrpS 82
Cdd:cd03253 1 IEFENVTFAYDpGRPVLKDVSFTIPAGKKVAIVGPSGSGKSTILRL--LFRFydVSSGSILIDGQDI------------R 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 83 NLKQiDRIRTQLGMVFQNFNLWsHKTVLENIIEApvhvlkRPQA---ECVEHAE--QLLEKV-GLADK-------RHYYp 149
Cdd:cd03253 67 EVTL-DSLRRAIGVVPQDTVLF-NDTIGYNIRYG------RPDAtdeEVIEAAKaaQIHDKImRFPDGydtivgeRGLK- 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 150 ahLSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLAdEGMTMLVVTHEMdfaREVSN--RIVFLHQG 227
Cdd:cd03253 138 --LSGGEKQRVAIARAILKNPPILLLDEATSALDTHTEREIQAALRDVS-KGRTTIVIAHRL---STIVNadKIIVLKDG 211
|
....*....
gi 497963481 228 EIEEQGTPE 236
Cdd:cd03253 212 RIVERGTHE 220
|
|
| ModF |
COG1119 |
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ... |
3-241 |
7.76e-32 |
|
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];
Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 117.11 E-value: 7.76e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 3 TPAISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRcsnLL--ELP--DQGEIIVGGEaiemkpnRKGq 78
Cdd:COG1119 1 DPLLELRNVTVRRGGKTILDDISWTVKPGEHWAILGPNGAGKSTLLS---LItgDLPptYGNDVRLFGE-------RRG- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 79 nRPSnlkqIDRIRTQLGMV----FQNFNlwSHKTVLENII---EAPVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAH 151
Cdd:COG1119 70 -GED----VWELRKRIGLVspalQLRFP--RDETVLDVVLsgfFDSIGLYREPTDEQRERARELLELLGLAHLADRPFGT 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 152 LSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEG-MTMLVVTHEMDFAREVSNRIVFLHQGEIE 230
Cdd:COG1119 143 LSQGEQRRVLIARALVKDPELLILDEPTAGLDLGARELLLALLDKLAAEGaPTLVLVTHHVEEIPPGITHVLLLKDGRVV 222
|
250
....*....|.
gi 497963481 231 EQGTPEHVFTA 241
Cdd:COG1119 223 AAGPKEEVLTS 233
|
|
| COG4674 |
COG4674 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
1-238 |
3.13e-31 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443710 [Multi-domain] Cd Length: 250 Bit Score: 115.60 E-value: 3.13e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 1 MTTPAISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLL-------RcsnllelPDQGEIIVGGEAIemkp 73
Cdd:COG4674 6 MHGPILYVEDLTVSFDGFKALNDLSLYVDPGELRVIIGPNGAGKTTLMdvitgktR-------PDSGSVLFGGTDL---- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 74 nrkgqnrpSNLKQIDRIRTQLGMVFQNFNLWSHKTVLENIIEA------PVHVLK-RPQAECVEHAEQLLEKVGLADKRH 146
Cdd:COG4674 75 --------TGLDEHEIARLGIGRKFQKPTVFEELTVFENLELAlkgdrgVFASLFaRLTAEERDRIEEVLETIGLTDKAD 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 147 YYPAHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDP---ELVGEVLRvmrTLAdEGMTMLVVTHEMDFAREVSNRIVF 223
Cdd:COG4674 147 RLAGLLSHGQKQWLEIGMLLAQDPKLLLLDEPVAGMTDaetERTAELLK---SLA-GKHSVVVVEHDMEFVRQIARKVTV 222
|
250
....*....|....*
gi 497963481 224 LHQGEIEEQGTPEHV 238
Cdd:COG4674 223 LHQGSVLAEGSLDEV 237
|
|
| ABCC_Glucan_exporter_like |
cd03254 |
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ... |
6-239 |
3.55e-31 |
|
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 115.02 E-value: 3.55e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLD-VLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEaiemkpnrkgqnrpsNL 84
Cdd:cd03254 3 IEFENVNFSYDEKKpVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGI---------------DI 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 85 KQIDRI--RTQLGMVFQNFNLWShKTVLENIIeapvhvLKRPQA---ECVE-----HAEQLLEKvgLADKRHYYPAH--- 151
Cdd:cd03254 68 RDISRKslRSMIGVVLQDTFLFS-GTIMENIR------LGRPNAtdeEVIEaakeaGAHDFIMK--LPNGYDTVLGEngg 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 152 -LSGGQQQRAAIARALAMEPKVMLFDEPTSALDPE---LVGEVLRVMRtladEGMTMLVVTHEMDFAREvSNRIVFLHQG 227
Cdd:cd03254 139 nLSQGERQLLAIARAMLRDPKILILDEATSNIDTEtekLIQEALEKLM----KGRTSIIIAHRLSTIKN-ADKILVLDDG 213
|
250
....*....|..
gi 497963481 228 EIEEQGTPEHVF 239
Cdd:cd03254 214 KIIEEGTHDELL 225
|
|
| ABC_Carb_Monos_II |
cd03215 |
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
4-229 |
3.83e-31 |
|
Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213182 [Multi-domain] Cd Length: 182 Bit Score: 113.30 E-value: 3.83e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 4 PAISLRNIHKSfgslDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEMKPNRkgqnrpsn 83
Cdd:cd03215 3 PVLEVRGLSVK----GAVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPVTRRSPR-------- 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 84 lkqiDRIRTQLGMV---------FQNFnlwshkTVLENIIeapvhvlkrpqaecvehaeqllekvgladkrhyYPAHLSG 154
Cdd:cd03215 71 ----DAIRAGIAYVpedrkreglVLDL------SVAENIA---------------------------------LSSLLSG 107
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 497963481 155 GQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEI 229
Cdd:cd03215 108 GNQQKVVLARWLARDPRVLILDEPTRGVDVGAKAEIYRLIRELADAGKAVLLISSELDELLGLCDRILVMYEGRI 182
|
|
| fecE |
PRK11231 |
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE; |
6-242 |
5.34e-31 |
|
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 115.11 E-value: 5.34e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEMKPNRKGQNRPSNLK 85
Cdd:PRK11231 3 LRTENLTVGYGTKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISMLSSRQLARRLALLP 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 86 QIdrIRTQLGMVFQNF---------NLWSHktvleniieapvhvLKRPQAECVEHAEQLLEKVGLADKRhyyPAHLSGGQ 156
Cdd:PRK11231 83 QH--HLTPEGITVRELvaygrspwlSLWGR--------------LSAEDNARVNQAMEQTRINHLADRR---LTDLSGGQ 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 157 QQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPE 236
Cdd:PRK11231 144 RQRAFLAMVLAQDTPVVLLDEPTTYLDINHQVELMRLMRELNTQGKTVVTVLHDLNQASRYCDHLVVLANGHVMAQGTPE 223
|
....*.
gi 497963481 237 HVFTAS 242
Cdd:PRK11231 224 EVMTPG 229
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
8-229 |
5.86e-31 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 119.78 E-value: 5.86e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 8 LRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRC-SNLLElPDQGEIIvggeaiemkpnrkgqnRPSNLKq 86
Cdd:COG0488 1 LENLSKSFGGRPLLDDVSLSINPGDRIGLVGRNGAGKSTLLKIlAGELE-PDSGEVS----------------IPKGLR- 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 87 idrirtqLGMVFQNFNLWSHKTVLENIIEA--PVHVLKRPQAECVEH-----------------------------AEQL 135
Cdd:COG0488 63 -------IGYLPQEPPLDDDLTVLDTVLDGdaELRALEAELEELEAKlaepdedlerlaelqeefealggweaearAEEI 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 136 LEKVGLADKRHYYP-AHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVgEVLRvmRTLADEGMTMLVVTHEMDFA 214
Cdd:COG0488 136 LSGLGFPEEDLDRPvSELSGGWRRRVALARALLSEPDLLLLDEPTNHLDLESI-EWLE--EFLKNYPGTVLVVSHDRYFL 212
|
250
....*....|....*
gi 497963481 215 REVSNRIVFLHQGEI 229
Cdd:COG0488 213 DRVATRILELDRGKL 227
|
|
| PRK14243 |
PRK14243 |
phosphate transporter ATP-binding protein; Provisional |
2-252 |
8.24e-31 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184588 [Multi-domain] Cd Length: 264 Bit Score: 114.88 E-value: 8.24e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 2 TTPAISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLE--LPD---QGEIIVGGEAIemkpnrk 76
Cdd:PRK14243 7 TETVLRTENLNVYYGSFLAVKNVWLDIPKNQITAFIGPSGCGKSTILRCFNRLNdlIPGfrvEGKVTFHGKNL------- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 77 gqnrpsNLKQID--RIRTQLGMVFQNFNLWShKTVLENIIEAP-VHVLKRPQAECVEHAeqlLEKVGL----ADKRHYYP 149
Cdd:PRK14243 80 ------YAPDVDpvEVRRRIGMVFQKPNPFP-KSIYDNIAYGArINGYKGDMDELVERS---LRQAALwdevKDKLKQSG 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 150 AHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLAdEGMTMLVVTHEMDFAREVSNRIVFLH---- 225
Cdd:PRK14243 150 LSLSGGQQQRLCIARAIAVQPEVILMDEPCSALDPISTLRIEELMHELK-EQYTIIIVTHNMQQAARVSDMTAFFNvelt 228
|
250 260 270
....*....|....*....|....*....|..
gi 497963481 226 -----QGEIEEQGTPEHVFTASQSARFRQFIA 252
Cdd:PRK14243 229 egggrYGYLVEFDRTEKIFNSPQQQATRDYVS 260
|
|
| PRK13537 |
PRK13537 |
nodulation factor ABC transporter ATP-binding protein NodI; |
1-243 |
1.20e-30 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 115.67 E-value: 1.20e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 1 MTTPAISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIemkPNRKgqnr 80
Cdd:PRK13537 3 MSVAPIDFRNVEKRYGDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPV---PSRA---- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 81 psnlkqiDRIRTQLGMVFQNFNLWSHKTVLENIIeapvhVLKR----PQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQ 156
Cdd:PRK13537 76 -------RHARQRVGVVPQFDNLDPDFTVRENLL-----VFGRyfglSAAAARALVPPLLEFAKLENKADAKVGELSGGM 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 157 QQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPe 236
Cdd:PRK13537 144 KRRLTLARALVNDPDVLVLDEPTTGLDPQARHLMWERLRSLLARGKTILLTTHFMEEAERLCDRLCVIEEGRKIAEGAP- 222
|
....*..
gi 497963481 237 HVFTASQ 243
Cdd:PRK13537 223 HALIESE 229
|
|
| ABC_MTABC3_MDL1_MDL2 |
cd03249 |
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ... |
6-236 |
1.31e-30 |
|
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.
Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 113.79 E-value: 1.31e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGS---LDVLKGISIEANQGEVISILGSSGSGKSTLLrcsNLLE---LPDQGEIIVGGEAIemkpnrkgqn 79
Cdd:cd03249 1 IEFKNVSFRYPSrpdVPILKGLSLTIPPGKTVALVGSSGCGKSTVV---SLLErfyDPTSGEILLDGVDI---------- 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 80 RPSNLKQIdriRTQLGMVFQNFNLWShKTVLENIIeapvhvLKRPQAEcVEHAEQLLEK-------VGLADKrhYYP--- 149
Cdd:cd03249 68 RDLNLRWL---RSQIGLVSQEPVLFD-GTIAENIR------YGKPDAT-DEEVEEAAKKanihdfiMSLPDG--YDTlvg 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 150 ---AHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDPE---LVGEVL-RVMRtladeGMTMLVVTHEMDFAREvSNRIV 222
Cdd:cd03249 135 ergSQLSGGQKQRIAIARALLRNPKILLLDEATSALDAEsekLVQEALdRAMK-----GRTTIVIAHRLSTIRN-ADLIA 208
|
250
....*....|....
gi 497963481 223 FLHQGEIEEQGTPE 236
Cdd:cd03249 209 VLQNGQVVEQGTHD 222
|
|
| type_I_sec_HlyB |
TIGR01846 |
type I secretion system ABC transporter, HlyB family; Type I protein secretion is a system in ... |
5-236 |
1.54e-30 |
|
type I secretion system ABC transporter, HlyB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273831 [Multi-domain] Cd Length: 694 Bit Score: 119.46 E-value: 1.54e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 5 AISLRNIHKSFG--SLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIemkpnrkGQNRPS 82
Cdd:TIGR01846 455 AITFENIRFRYApdSPEVLSNLNLDIKPGEFIGIVGPSGSGKSTLTKLLQRLYTPQHGQVLVDGVDL-------AIADPA 527
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 83 NLkqidriRTQLGMVFQNFNLWShKTVLENIieapvhVLKRPQA--ECVEHAEQLL--EKVGLADKRHY------YPAHL 152
Cdd:TIGR01846 528 WL------RRQMGVVLQENVLFS-RSIRDNI------ALCNPGApfEHVIHAAKLAgaHDFISELPQGYntevgeKGANL 594
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 153 SGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLAdEGMTMLVVTHEMDFAREvSNRIVFLHQGEIEEQ 232
Cdd:TIGR01846 595 SGGQRQRIAIARALVGNPRILIFDEATSALDYESEALIMRNMREIC-RGRTVIIIAHRLSTVRA-CDRIIVLEKGQIAES 672
|
....
gi 497963481 233 GTPE 236
Cdd:TIGR01846 673 GRHE 676
|
|
| cbiO |
PRK13642 |
energy-coupling factor transporter ATPase; |
21-243 |
1.84e-30 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184202 [Multi-domain] Cd Length: 277 Bit Score: 114.42 E-value: 1.84e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 21 LKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIemkpnrkgqnrpsNLKQIDRIRTQLGMVFQN 100
Cdd:PRK13642 23 LNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGELL-------------TAENVWNLRRKIGMVFQN 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 101 FNLWSHKTVLENIIEAPVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIARALAMEPKVMLFDEPTS 180
Cdd:PRK13642 90 PDNQFVGATVEDDVAFGMENQGIPREEMIKRVDEALLAVNMLDFKTREPARLSGGQKQRVAVAGIIALRPEIIILDESTS 169
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 497963481 181 ALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREvSNRIVFLHQGEIEEQGTPEHVFTASQ 243
Cdd:PRK13642 170 MLDPTGRQEIMRVIHEIKEKyQLTVLSITHDLDEAAS-SDRILVMKAGEIIKEAAPSELFATSE 232
|
|
| CP_lyasePhnK |
TIGR02323 |
phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P ... |
4-240 |
4.53e-30 |
|
phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P lyase systems for utilization of phosphonates. These systems resemble phosphonatase-based systems in having a three component ABC transporter, where TIGR01097 is the permease, TIGR01098 is the phosphonates binding protein, and TIGR02315 is the ATP-binding cassette (ABC) protein. They differ, however, in having, typically, ten or more additional genes, many of which are believed to form a membrane-associated complex. This protein (PhnK) and the adjacent-encoded PhnL resemble transporter ATP-binding proteins but are suggested, based on mutatgenesis studies, to be part of this complex rather than part of a transporter per se. [Central intermediary metabolism, Phosphorus compounds]
Pssm-ID: 188208 [Multi-domain] Cd Length: 253 Bit Score: 112.62 E-value: 4.53e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 4 PAISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGgeaiemkpNRKGQNRP-S 82
Cdd:TIGR02323 2 PLLQVSGLSKSYGGGKGCRDVSFDLYPGEVLGIVGESGSGKSTLLGCLAGRLAPDHGTATYI--------MRSGAELElY 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 83 NLKQIDR---IRTQLGMVFQNFNLWSHKTVLE--NIIEAPVHVLKRPQAECVEHAEQLLEKVGL-ADKRHYYPAHLSGGQ 156
Cdd:TIGR02323 74 QLSEAERrrlMRTEWGFVHQNPRDGLRMRVSAgaNIGERLMAIGARHYGNIRATAQDWLEEVEIdPTRIDDLPRAFSGGM 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 157 QQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLA-DEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQG-- 233
Cdd:TIGR02323 154 QQRLQIARNLVTRPRLVFMDEPTGGLDVSVQARLLDLLRGLVrDLGLAVIIVTHDLGVARLLAQRLLVMQQGRVVESGlt 233
|
250
....*....|..
gi 497963481 234 -----TPEHVFT 240
Cdd:TIGR02323 234 dqvldDPQHPYT 245
|
|
| cbiO |
PRK13638 |
energy-coupling factor ABC transporter ATP-binding protein; |
20-243 |
9.74e-30 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184198 [Multi-domain] Cd Length: 271 Bit Score: 112.41 E-value: 9.74e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 20 VLKGISIEANQGEVISILGSSGSGKSTL-LRCSNLLElPDQGEIIVGGEAIEMkpNRKGqnrpsnlkqIDRIRTQLGMVF 98
Cdd:PRK13638 16 VLKGLNLDFSLSPVTGLVGANGCGKSTLfMNLSGLLR-PQKGAVLWQGKPLDY--SKRG---------LLALRQQVATVF 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 99 QNFNLWSHKTVLENIIEAPVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIARALAMEPKVMLFDEP 178
Cdd:PRK13638 84 QDPEQQIFYTDIDSDIAFSLRNLGVPEAEITRRVDEALTLVDAQHFRHQPIQCLSHGQKKRVAIAGALVLQARYLLLDEP 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 497963481 179 TSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVFTASQ 243
Cdd:PRK13638 164 TAGLDPAGRTQMIAIIRRIVAQGNHVIISSHDIDLIYEISDAVYVLRQGQILTHGAPGEVFACTE 228
|
|
| type_I_sec_LssB |
TIGR03375 |
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some ... |
20-246 |
1.00e-29 |
|
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. This model is related to models TIGR01842 and TIGR01846, and to bacteriocin ABC transporters that cleave their substrates during export. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]
Pssm-ID: 274550 [Multi-domain] Cd Length: 694 Bit Score: 116.89 E-value: 1.00e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 20 VLKGISIEANQGEVISILGSSGSGKSTLLR-CSNLLElPDQGEIIVGGEAIemkpnrkgqnrpsnlKQIDR--IRTQLGM 96
Cdd:TIGR03375 480 ALDNVSLTIRPGEKVAIIGRIGSGKSTLLKlLLGLYQ-PTEGSVLLDGVDI---------------RQIDPadLRRNIGY 543
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 97 VFQNFNLWsHKTVLENIIeapvhvLKRPQAECVEHAEqLLEKVGLAD--KRHyyP-----------AHLSGGQQQRAAIA 163
Cdd:TIGR03375 544 VPQDPRLF-YGTLRDNIA------LGAPYADDEEILR-AAELAGVTEfvRRH--PdgldmqigergRSLSGGQRQAVALA 613
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 164 RALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLAdEGMTMLVVTHEMDFAREVsNRIVFLHQGEIEEQGTPEHVFTASQ 243
Cdd:TIGR03375 614 RALLRDPPILLLDEPTSAMDNRSEERFKDRLKRWL-AGKTLVLVTHRTSLLDLV-DRIIVMDNGRIVADGPKDQVLEALR 691
|
...
gi 497963481 244 SAR 246
Cdd:TIGR03375 692 KGR 694
|
|
| cbiO |
PRK13646 |
energy-coupling factor transporter ATPase; |
21-239 |
1.73e-29 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184205 [Multi-domain] Cd Length: 286 Bit Score: 112.18 E-value: 1.73e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 21 LKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEMKpnrkgqnrpSNLKQIDRIRTQLGMVFQ- 99
Cdd:PRK13646 23 IHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITITHK---------TKDKYIRPVRKRIGMVFQf 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 100 -NFNLWsHKTVLENIIEAPVHvLKRPQAECVEHAEQLLEKVGLA-DKRHYYPAHLSGGQQQRAAIARALAMEPKVMLFDE 177
Cdd:PRK13646 94 pESQLF-EDTVEREIIFGPKN-FKMNLDEVKNYAHRLLMDLGFSrDVMSQSPFQMSGGQMRKIAIVSILAMNPDIIVLDE 171
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 497963481 178 PTSALDPELVGEVLRVMRTLA-DEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVF 239
Cdd:PRK13646 172 PTAGLDPQSKRQVMRLLKSLQtDENKTIILVSHDMNEVARYADEVIVMKEGSIVSQTSPKELF 234
|
|
| PRK11831 |
PRK11831 |
phospholipid ABC transporter ATP-binding protein MlaF; |
6-251 |
3.43e-29 |
|
phospholipid ABC transporter ATP-binding protein MlaF;
Pssm-ID: 236997 [Multi-domain] Cd Length: 269 Bit Score: 111.01 E-value: 3.43e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIemkpnrkgqnrPS-NL 84
Cdd:PRK11831 8 VDMRGVSFTRGNRCIFDNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGENI-----------PAmSR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 85 KQIDRIRTQLGMVFQNFNLWSHKTVLENIieapvhvlKRPQAECVEHAEQL--------LEKVGLADKRHYYPAHLSGGQ 156
Cdd:PRK11831 77 SRLYTVRKRMSMLFQSGALFTDMNVFDNV--------AYPLREHTQLPAPLlhstvmmkLEAVGLRGAAKLMPSELSGGM 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 157 QQRAAIARALAMEPKVMLFDEPTSALDPELVGevlrVMRTLADE-----GMTMLVVTHEMDFAREVSNRIVFLHQGEIEE 231
Cdd:PRK11831 149 ARRAALARAIALEPDLIMFDEPFVGQDPITMG----VLVKLISElnsalGVTCVVVSHDVPEVLSIADHAYIVADKKIVA 224
|
250 260
....*....|....*....|
gi 497963481 232 QGTPEHVfTASQSARFRQFI 251
Cdd:PRK11831 225 HGSAQAL-QANPDPRVRQFL 243
|
|
| ABCG_EPDR |
cd03213 |
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ... |
16-229 |
1.82e-28 |
|
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.
Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 106.87 E-value: 1.82e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 16 GSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSN--LLELPDQGEIIVGGEAIEMkpnrkgqnrpsnlkqiDRIRTQ 93
Cdd:cd03213 20 SGKQLLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAgrRTGLGVSGEVLINGRPLDK----------------RSFRKI 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 94 LGMVFQNFNLWSHKTVLENIieapvhvlkrpqaecvehaeqllekvgladkrhYYPAHL---SGGQQQRAAIARALAMEP 170
Cdd:cd03213 84 IGYVPQDDILHPTLTVRETL---------------------------------MFAAKLrglSGGERKRVSIALELVSNP 130
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 497963481 171 KVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTH----EMdFarEVSNRIVFLHQGEI 229
Cdd:cd03213 131 SLLFLDEPTSGLDSSSALQVMSLLRRLADTGRTIICSIHqpssEI-F--ELFDKLLLLSQGRV 190
|
|
| TagH |
COG1134 |
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ... |
3-241 |
3.01e-28 |
|
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 107.47 E-value: 3.01e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 3 TPAISLRNIHKSF-------GSLD---------------VLKGISIEANQGEVISILGSSGSGKSTLLRC-SNLLElPDQ 59
Cdd:COG1134 2 SSMIEVENVSKSYrlyhepsRSLKelllrrrrtrreefwALKDVSFEVERGESVGIIGRNGAGKSTLLKLiAGILE-PTS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 60 GEIIVGGeaiemkpnrkgqnRPSNLkqIDrirtqLGMVFQNfNLwshkTVLENII-EAPVHVLKRPQ-----AECVEHAE 133
Cdd:COG1134 81 GRVEVNG-------------RVSAL--LE-----LGAGFHP-EL----TGRENIYlNGRLLGLSRKEidekfDEIVEFAE 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 134 qlLEK-----VgladkRHYypahlSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVT 208
Cdd:COG1134 136 --LGDfidqpV-----KTY-----SSGMRARLAFAVATAVDPDILLVDEVLAVGDAAFQKKCLARIRELRESGRTVIFVS 203
|
250 260 270
....*....|....*....|....*....|...
gi 497963481 209 HEMDFAREVSNRIVFLHQGEIEEQGTPEHVFTA 241
Cdd:COG1134 204 HSMGAVRRLCDRAIWLEKGRLVMDGDPEEVIAA 236
|
|
| CydC |
TIGR02868 |
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ... |
4-209 |
3.28e-28 |
|
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.
Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 112.07 E-value: 3.28e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 4 PAISLRNIHKSF-GSLDVLKGISIEANQGEVISILGSSGSGKSTLLrcSNLLEL--PDQGEIIVGGEAiemkpnrkgqnr 80
Cdd:TIGR02868 333 PTLELRDLSAGYpGAPPVLDGVSLDLPPGERVAILGPSGSGKSTLL--ATLAGLldPLQGEVTLDGVP------------ 398
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 81 PSNLKQiDRIRTQLGMVFQNFNLWsHKTVLENIIeapvhvLKRPQAEcVEHAEQLLEKVGLADKRHYYP----------- 149
Cdd:TIGR02868 399 VSSLDQ-DEVRRRVSVCAQDAHLF-DTTVRENLR------LARPDAT-DEELWAALERVGLADWLRALPdgldtvlgegg 469
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 150 AHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTlADEGMTMLVVTH 209
Cdd:TIGR02868 470 ARLSGGERQRLALARALLADAPILLLDEPTEHLDAETADELLEDLLA-ALSGRTVVLITH 528
|
|
| PRK15079 |
PRK15079 |
oligopeptide ABC transporter ATP-binding protein OppF; Provisional |
17-239 |
6.29e-28 |
|
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
Pssm-ID: 185037 [Multi-domain] Cd Length: 331 Bit Score: 108.64 E-value: 6.29e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 17 SLDVLKGISIEANQGEVISILGSSGSGKSTLLRCS-NLLELPDqGEII-VGGEAIEMKPnrkgqnrpsnlKQIDRIRTQL 94
Cdd:PRK15079 33 TLKAVDGVTLRLYEGETLGVVGESGCGKSTFARAIiGLVKATD-GEVAwLGKDLLGMKD-----------DEWRAVRSDI 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 95 GMVFQN--FNLWSHKTVLEnIIEAPVHVL--KRPQAECVEHAEQLLEKVGL-ADKRHYYPAHLSGGQQQRAAIARALAME 169
Cdd:PRK15079 101 QMIFQDplASLNPRMTIGE-IIAEPLRTYhpKLSRQEVKDRVKAMMLKVGLlPNLINRYPHEFSGGQCQRIGIARALILE 179
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 497963481 170 PKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVF 239
Cdd:PRK15079 180 PKLIICDEPVSALDVSIQAQVVNLLQQLQREmGLSLIFIAHDLAVVKHISDRVLVMYLGHAVELGTYDEVY 250
|
|
| PRK10584 |
PRK10584 |
putative ABC transporter ATP-binding protein YbbA; Provisional |
4-232 |
8.07e-28 |
|
putative ABC transporter ATP-binding protein YbbA; Provisional
Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 106.02 E-value: 8.07e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 4 PAISLRNIH---KSFGS----LDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAI-EMKPNR 75
Cdd:PRK10584 2 PAENIVEVHhlkKSVGQgeheLSILTGVELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLhQMDEEA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 76 KGQNRPSNLkqidrirtqlGMVFQNFNLWSHKTVLENIiEAPVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGG 155
Cdd:PRK10584 82 RAKLRAKHV----------GFVFQSFMLIPTLNALENV-ELPALLRGESSRQSRNGAKALLEQLGLGKRLDHLPAQLSGG 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 497963481 156 QQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTL-ADEGMTMLVVTHEMDFAREVSNRIVfLHQGEIEEQ 232
Cdd:PRK10584 151 EQQRVALARAFNGRPDVLFADEPTGNLDRQTGDKIADLLFSLnREHGTTLILVTHDLQLAARCDRRLR-LVNGQLQEE 227
|
|
| CydD |
TIGR02857 |
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ... |
4-209 |
2.48e-27 |
|
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD
Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 109.68 E-value: 2.48e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 4 PAISLRNIHKSF-GSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAiemkpnrkgqnrps 82
Cdd:TIGR02857 320 SSLEFSGVSVAYpGRRPALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVP-------------- 385
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 83 nLKQIDR--IRTQLGMVFQNFNLWShKTVLENII----EAPVHVLKRPQ-----AECVEHAEQLLEKvgLADKRhyyPAH 151
Cdd:TIGR02857 386 -LADADAdsWRDQIAWVPQHPFLFA-GTIAENIRlarpDASDAEIREALeraglDEFVAALPQGLDT--PIGEG---GAG 458
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 497963481 152 LSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLAdEGMTMLVVTH 209
Cdd:TIGR02857 459 LSGGQAQRLALARAFLRDAPLLLLDEPTAHLDAETEAEVLEALRALA-QGRTVLLVTH 515
|
|
| PRK11160 |
PRK11160 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
2-251 |
3.01e-27 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 109.53 E-value: 3.01e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 2 TTPAISLRNIHKSF--GSLDVLKGISIEANQGEVISILGSSGSGKSTLLrcsNLLE---LPDQGEIIVGGEAIemkpnrk 76
Cdd:PRK11160 335 DQVSLTLNNVSFTYpdQPQPVLKGLSLQIKAGEKVALLGRTGCGKSTLL---QLLTrawDPQQGEILLNGQPI------- 404
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 77 gqnrpSNLKQiDRIRTQLGMVFQNFNLWSHkTVLENIieapvhVLKRPQAecveHAEQL---LEKVGLA-----DK---- 144
Cdd:PRK11160 405 -----ADYSE-AALRQAISVVSQRVHLFSA-TLRDNL------LLAAPNA----SDEALievLQQVGLEklledDKglna 467
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 145 ------RhyypaHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLAdEGMTMLVVTH------EMD 212
Cdd:PRK11160 468 wlgeggR-----QLSGGEQRRLGIARALLHDAPLLLLDEPTEGLDAETERQILELLAEHA-QNKTVLMITHrltgleQFD 541
|
250 260 270
....*....|....*....|....*....|....*....
gi 497963481 213 farevsnRIVFLHQGEIEEQGTpeHVFTASQSARFRQFI 251
Cdd:PRK11160 542 -------RICVMDNGQIIEQGT--HQELLAQQGRYYQLK 571
|
|
| MsbA_lipidA |
TIGR02203 |
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ... |
6-234 |
3.35e-27 |
|
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]
Pssm-ID: 131258 [Multi-domain] Cd Length: 571 Bit Score: 109.42 E-value: 3.35e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFG--SLDVLKGISIEANQGEVISILGSSGSGKSTLLrcsNLLE---LPDQGEIIVGGEAIEmkpnrkgqnr 80
Cdd:TIGR02203 331 VEFRNVTFRYPgrDRPALDSISLVIEPGETVALVGRSGSGKSTLV---NLIPrfyEPDSGQILLDGHDLA---------- 397
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 81 psNLKqIDRIRTQLGMVFQNFNLWShKTVLENIIEAPVHVLKRPQAECVEHAEQLLEKVGLADKRHYYP-----AHLSGG 155
Cdd:TIGR02203 398 --DYT-LASLRRQVALVSQDVVLFN-DTIANNIAYGRTEQADRAEIERALAAAYAQDFVDKLPLGLDTPigengVLLSGG 473
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 156 QQQRAAIARALAMEPKVMLFDEPTSALDPE---LVGEVL-RVMRtladeGMTMLVVTHEMDfAREVSNRIVFLHQGEIEE 231
Cdd:TIGR02203 474 QRQRLAIARALLKDAPILILDEATSALDNEserLVQAALeRLMQ-----GRTTLVIAHRLS-TIEKADRIVVMDDGRIVE 547
|
...
gi 497963481 232 QGT 234
Cdd:TIGR02203 548 RGT 550
|
|
| ABCC_Protease_Secretion |
cd03246 |
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ... |
6-229 |
5.18e-27 |
|
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.
Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 102.29 E-value: 5.18e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLD--VLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEmkpnrkgQNRPSN 83
Cdd:cd03246 1 LEVENVSFRYPGAEppVLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADIS-------QWDPNE 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 84 LkqidriRTQLGMVFQNFNLWShKTVLENIieapvhvlkrpqaecvehaeqllekvgladkrhyypahLSGGQQQRAAIA 163
Cdd:cd03246 74 L------GDHVGYLPQDDELFS-GSIAENI--------------------------------------LSGGQRQRLGLA 108
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 497963481 164 RALAMEPKVMLFDEPTSALDPElvGE--VLRVMRTLADEGMTMLVVTHEMDFAREVsNRIVFLHQGEI 229
Cdd:cd03246 109 RALYGNPRILVLDEPNSHLDVE--GEraLNQAIAALKAAGATRIVIAHRPETLASA-DRILVLEDGRV 173
|
|
| ABCC_cytochrome_bd |
cd03247 |
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ... |
6-233 |
6.27e-27 |
|
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.
Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 102.39 E-value: 6.27e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLD--VLKGISIEANQGEVISILGSSGSGKSTLLRcsnLLE---LPDQGEIIVGGEAIemkpnrkgqnr 80
Cdd:cd03247 1 LSINNVSFSYPEQEqqVLKNLSLELKQGEKIALLGRSGSGKSTLLQ---LLTgdlKPQQGEITLDGVPV----------- 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 81 pSNLKqiDRIRTQLGMVFQNFNLWShKTVLENIieapvhvlkrpqaecvehaeqllekvgladkrhyyPAHLSGGQQQRA 160
Cdd:cd03247 67 -SDLE--KALSSLISVLNQRPYLFD-TTLRNNL-----------------------------------GRRFSGGERQRL 107
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 497963481 161 AIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLAdEGMTMLVVTHEMDfAREVSNRIVFLHQGEIEEQG 233
Cdd:cd03247 108 ALARILLQDAPIVLLDEPTVGLDPITERQLLSLIFEVL-KDKTLIWITHHLT-GIEHMDKILFLENGKIIMQG 178
|
|
| PRK13536 |
PRK13536 |
nodulation factor ABC transporter ATP-binding protein NodI; |
1-236 |
6.77e-27 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 106.07 E-value: 6.77e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 1 MTTPAISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIemkpnrkgqnr 80
Cdd:PRK13536 37 MSTVAIDLAGVSKSYGDKAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLGVPV----------- 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 81 PSnlkQIDRIRTQLGMVFQNFNLWSHKTVLENIIEAPVHV-LKRPQAECVehAEQLLEKVGLADKRHYYPAHLSGGQQQR 159
Cdd:PRK13536 106 PA---RARLARARIGVVPQFDNLDLEFTVRENLLVFGRYFgMSTREIEAV--IPSLLEFARLESKADARVSDLSGGMKRR 180
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 497963481 160 AAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPE 236
Cdd:PRK13536 181 LTLARALINDPQLLILDEPTTGLDPHARHLIWERLRSLLARGKTILLTTHFMEEAERLCDRLCVLEAGRKIAEGRPH 257
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
4-229 |
6.83e-27 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 108.18 E-value: 6.83e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 4 PAISLRNIHKSfgslDVLKGISIEANQGEVISILGSSGSGKSTLLRCsnL--LELPDQGEIIVGGEAIEMKpnrkgqnRP 81
Cdd:COG1129 255 VVLEVEGLSVG----GVVRDVSFSVRAGEILGIAGLVGAGRTELARA--LfgADPADSGEIRLDGKPVRIR-------SP 321
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 82 SnlkqiDRIRtqLGMVF-----QNFNLWSHKTVLENIIEAPVHVLKR-----PQAEcVEHAEQLLEKVGLADKRHYYPA- 150
Cdd:COG1129 322 R-----DAIR--AGIAYvpedrKGEGLVLDLSIRENITLASLDRLSRgglldRRRE-RALAEEYIKRLRIKTPSPEQPVg 393
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 151 HLSGGQQQRAAIARALAMEPKVMLFDEPTSALDpelVG---EVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQG 227
Cdd:COG1129 394 NLSGGNQQKVVLAKWLATDPKVLILDEPTRGID---VGakaEIYRLIRELAAEGKAVIVISSELPELLGLSDRILVMREG 470
|
..
gi 497963481 228 EI 229
Cdd:COG1129 471 RI 472
|
|
| AztA |
NF040873 |
zinc ABC transporter ATP-binding protein AztA; |
14-216 |
1.11e-26 |
|
zinc ABC transporter ATP-binding protein AztA;
Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 102.31 E-value: 1.11e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 14 SFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAiemkpnrkgqnRPSNLKQIDRIRTQ 93
Cdd:NF040873 1 GYGGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRAGGA-----------RVAYVPQRSEVPDS 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 94 L-----GMVfqNFNLWSHKTVLeniieapvhvlKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIARALAM 168
Cdd:NF040873 70 LpltvrDLV--AMGRWARRGLW-----------RRLTRDDRAAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQ 136
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 497963481 169 EPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFARE 216
Cdd:NF040873 137 EADLLLLDEPTTGLDAESRERIIALLAEEHARGATVVVVTHDLELVRR 184
|
|
| ABCG_White |
cd03234 |
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ... |
17-233 |
1.27e-26 |
|
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.
Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 103.12 E-value: 1.27e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 17 SLDVLKGISIEANQGEVISILGSSGSGKSTLLrcsnllelpdqgEIIVGgeAIEMKPNRKGQ----NRPSNLKQIDRIrt 92
Cdd:cd03234 19 YARILNDVSLHVESGQVMAILGSSGSGKTTLL------------DAISG--RVEGGGTTSGQilfnGQPRKPDQFQKC-- 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 93 qLGMVFQNFNLWSHKTVLENIIEAPVHVLKRPQAECV---EHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIARALAME 169
Cdd:cd03234 83 -VAYVRQDDILLPGLTVRETLTYTAILRLPRKSSDAIrkkRVEDVLLRDLALTRIGGNLVKGISGGERRRVSIAVQLLWD 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 497963481 170 PKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTH----EMdFarEVSNRIVFLHQGEIEEQG 233
Cdd:cd03234 162 PKVLILDEPTSGLDSFTALNLVSTLSQLARRNRIVILTIHqprsDL-F--RLFDRILLLSSGEIVYSG 226
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
24-253 |
1.49e-26 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 107.63 E-value: 1.49e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 24 ISIEANQGEVISILGSSGSGKSTLLRCsnLLELPD--QGEIIVGGEAIEMKPNRKGQNrpsnlkqidrIRTQLGMVFQN- 100
Cdd:PRK10261 343 VSFDLWPGETLSLVGESGSGKSTTGRA--LLRLVEsqGGEIIFNGQRIDTLSPGKLQA----------LRRDIQFIFQDp 410
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 101 -FNLWSHKTVLENIIEaPVHVLKRPQAECV-EHAEQLLEKVGLADKRHY-YPAHLSGGQQQRAAIARALAMEPKVMLFDE 177
Cdd:PRK10261 411 yASLDPRQTVGDSIME-PLRVHGLLPGKAAaARVAWLLERVGLLPEHAWrYPHEFSGGQRQRICIARALALNPKVIIADE 489
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 497963481 178 PTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVFTASQSARFRQFIAS 253
Cdd:PRK10261 490 AVSALDVSIRGQIINLLLDLQRDfGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGPRRAVFENPQHPYTRKLMAA 566
|
|
| tauB |
PRK11248 |
taurine ABC transporter ATP-binding subunit; |
5-246 |
2.77e-26 |
|
taurine ABC transporter ATP-binding subunit;
Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 102.86 E-value: 2.77e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 5 AISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEmkpnRKGQNRpsnl 84
Cdd:PRK11248 1 MLQISHLYADYGGKPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKPVE----GPGAER---- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 85 kqidrirtqlGMVFQNFNLWSHKTVLENIiEAPVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIAR 164
Cdd:PRK11248 73 ----------GVVFQNEGLLPWRNVQDNV-AFGLQLAGVEKMQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIAR 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 165 ALAMEPKVMLFDEPTSALDP---ELVGEVLrvMRTLADEGMTMLVVTHEMDFAREVSNRIVFLH--QGEIEEQGTPE--H 237
Cdd:PRK11248 142 ALAANPQLLLLDEPFGALDAftrEQMQTLL--LKLWQETGKQVLLITHDIEEAVFMATELVLLSpgPGRVVERLPLNfaR 219
|
....*....
gi 497963481 238 VFTASQSAR 246
Cdd:PRK11248 220 RFVAGESSR 228
|
|
| ABCC_MsbA |
cd03251 |
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ... |
20-234 |
3.67e-26 |
|
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 101.92 E-value: 3.67e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 20 VLKGISIEANQGEVISILGSSGSGKSTLLrcsNLLEL---PDQGEIIVGGEAIemkpnrkgqnRPSNLKQIdriRTQLGM 96
Cdd:cd03251 17 VLRDISLDIPAGETVALVGPSGSGKSTLV---NLIPRfydVDSGRILIDGHDV----------RDYTLASL---RRQIGL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 97 VFQNFNLWShKTVLENIIEApvhvlkRPQA--ECVEHAEQLLEkvgladkrhyypAH--------------------LSG 154
Cdd:cd03251 81 VSQDVFLFN-DTVAENIAYG------RPGAtrEEVEEAARAAN------------AHefimelpegydtvigergvkLSG 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 155 GQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLAdEGMTMLVVTHEMDFAREvSNRIVFLHQGEIEEQGT 234
Cdd:cd03251 142 GQRQRIAIARALLKDPPILILDEATSALDTESERLVQAALERLM-KNRTTFVIAHRLSTIEN-ADRIVVLEDGKIVERGT 219
|
|
| 3a01204 |
TIGR00955 |
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ... |
21-237 |
3.93e-26 |
|
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 106.67 E-value: 3.93e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 21 LKGISIEANQGEVISILGSSGSGKSTL---LRCSNLLELPDQGEIIVGGEAIemkpnrkgqnrpsNLKQIDRIRtqlGMV 97
Cdd:TIGR00955 41 LKNVSGVAKPGELLAVMGSSGAGKTTLmnaLAFRSPKGVKGSGSVLLNGMPI-------------DAKEMRAIS---AYV 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 98 FQNFNLWSHKTVLENIIEAPVHVLKR--PQAECVEHAEQLLEKVGLADKRH------YYPAHLSGGQQQRAAIARALAME 169
Cdd:TIGR00955 105 QQDDLFIPTLTVREHLMFQAHLRMPRrvTKKEKRERVDEVLQALGLRKCANtrigvpGRVKGLSGGERKRLAFASELLTD 184
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 497963481 170 PKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMD---FarEVSNRIVFLHQGEIEEQGTPEH 237
Cdd:TIGR00955 185 PPLLFCDEPTSGLDSFMAYSVVQVLKGLAQKGKTIICTIHQPSselF--ELFDKIILMAEGRVAYLGSPDQ 253
|
|
| PRK10895 |
PRK10895 |
lipopolysaccharide ABC transporter ATP-binding protein; Provisional |
10-246 |
6.53e-26 |
|
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 101.51 E-value: 6.53e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 10 NIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEMKPNRkgqnrpsnlkqiDR 89
Cdd:PRK10895 8 NLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDISLLPLH------------AR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 90 IRTQLGMVFQNFNLWSHKTVLENIIeAPVHVLKRPQAEC-VEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIARALAM 168
Cdd:PRK10895 76 ARRGIGYLPQEASIFRRLSVYDNLM-AVLQIRDDLSAEQrEDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAA 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 497963481 169 EPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVFTASQSAR 246
Cdd:PRK10895 155 NPKFILLDEPFAGVDPISVIDIKRIIEHLRDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGTPTEILQDEHVKR 232
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
4-235 |
9.07e-26 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 105.87 E-value: 9.07e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 4 PAISLRNIHKSF--GSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEMkpnrkgqnrp 81
Cdd:TIGR01257 927 PGVCVKNLVKIFepSGRPAVDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKDIET---------- 996
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 82 snlkQIDRIRTQLGMVFQNFNLWSHKTVLENIIEApVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAA 161
Cdd:TIGR01257 997 ----NLDAVRQSLGMCPQHNILFHHLTVAEHILFY-AQLKGRSWEEAQLEMEAMLEDTGLHHKRNEEAQDLSGGMQRKLS 1071
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 497963481 162 IARALAMEPKVMLFDEPTSALDP---ELVGEVLRVMRTladeGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTP 235
Cdd:TIGR01257 1072 VAIAFVGDAKVVVLDEPTSGVDPysrRSIWDLLLKYRS----GRTIIMSTHHMDEADLLGDRIAIISQGRLYCSGTP 1144
|
|
| ABCC_bacteriocin_exporters |
cd03245 |
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ... |
19-233 |
1.14e-25 |
|
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.
Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 100.36 E-value: 1.14e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 19 DVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGeaiemkpnrkgqnrpSNLKQIDR--IRTQLGM 96
Cdd:cd03245 18 PALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDG---------------TDIRQLDPadLRRNIGY 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 97 VFQNFNLWShKTVLENIieapvhVLKRPQAEcvehAEQLLEKVGLADKRHYYPAH--------------LSGGQQQRAAI 162
Cdd:cd03245 83 VPQDVTLFY-GTLRDNI------TLGAPLAD----DERILRAAELAGVTDFVNKHpngldlqigergrgLSGGQRQAVAL 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 497963481 163 ARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLAdEGMTMLVVTHEMDFAREVsNRIVFLHQGEIEEQG 233
Cdd:cd03245 152 ARALLNDPPILLLDEPTSAMDMNSEERLKERLRQLL-GDKTLIIITHRPSLLDLV-DRIIVMDSGRIVADG 220
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
1-253 |
1.38e-25 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 104.79 E-value: 1.38e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 1 MTTPAISLRNIHKSFGSLD----VLKGISIEANQGEVISILGSSGSGKS-TLLRCSNLLELPD----QGEIIVGGEAIEM 71
Cdd:PRK15134 1 MTQPLLAIENLSVAFRQQQtvrtVVNDVSLQIEAGETLALVGESGSGKSvTALSILRLLPSPPvvypSGDIRFHGESLLH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 72 KPNRkgqnrpsnlkQIDRIR-TQLGMVFQN--FNLWSHKTVLENIIEapVHVLKRPQAECVEHAEQL--LEKVGL--ADK 144
Cdd:PRK15134 81 ASEQ----------TLRGVRgNKIAMIFQEpmVSLNPLHTLEKQLYE--VLSLHRGMRREAARGEILncLDRVGIrqAAK 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 145 R-HYYPAHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIV 222
Cdd:PRK15134 149 RlTDYPHQLSGGERQRVMIAMALLTRPELLIADEPTTALDVSVQAQILQLLRELQQElNMGLLFITHNLSIVRKLADRVA 228
|
250 260 270
....*....|....*....|....*....|.
gi 497963481 223 FLHQGEIEEQGTPEHVFTASQSARFRQFIAS 253
Cdd:PRK15134 229 VMQNGRCVEQNRAATLFSAPTHPYTQKLLNS 259
|
|
| dppD |
PRK11022 |
dipeptide transporter ATP-binding subunit; Provisional |
24-241 |
1.49e-25 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 182906 [Multi-domain] Cd Length: 326 Bit Score: 102.51 E-value: 1.49e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 24 ISIEANQGEVISILGSSGSGKS-TLLRCSNLLELPDQgeiiVGGEAIEMKPNRKGQNRPSNLKQIdrIRTQLGMVFQN-- 100
Cdd:PRK11022 26 ISYSVKQGEVVGIVGESGSGKSvSSLAIMGLIDYPGR----VMAEKLEFNGQDLQRISEKERRNL--VGAEVAMIFQDpm 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 101 FNLWSHKTVLENIIEApvhvLKRPQ----AECVEHAEQLLEKVGLAD---KRHYYPAHLSGGQQQRAAIARALAMEPKVM 173
Cdd:PRK11022 100 TSLNPCYTVGFQIMEA----IKVHQggnkKTRRQRAIDLLNQVGIPDpasRLDVYPHQLSGGMSQRVMIAMAIACRPKLL 175
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 497963481 174 LFDEPTSALDPELVGEVLRVMRTLAD-EGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVFTA 241
Cdd:PRK11022 176 IADEPTTALDVTIQAQIIELLLELQQkENMALVLITHDLALVAEAAHKIIVMYAGQVVETGKAHDIFRA 244
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
4-231 |
2.19e-25 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 103.99 E-value: 2.19e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 4 PAISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRC-SNLLElPDQGEIIVGgeaiemkpnrkgqnrpS 82
Cdd:COG0488 314 KVLELEGLSKSYGDKTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLlAGELE-PDSGTVKLG----------------E 376
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 83 NLKqidrirtqLGMVFQNF-NLWSHKTVLENIIEApvhvlkRPQAEcVEHAEQLLEKVGLADKRHYYPAH-LSGGQQQRA 160
Cdd:COG0488 377 TVK--------IGYFDQHQeELDPDKTVLDELRDG------APGGT-EQEVRGYLGRFLFSGDDAFKPVGvLSGGEKARL 441
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 497963481 161 AIARALAMEPKVMLFDEPTSALDPELVgEVLrvMRTLAD-EGmTMLVVTHEMDFAREVSNRIVFLHQGEIEE 231
Cdd:COG0488 442 ALAKLLLSPPNVLLLDEPTNHLDIETL-EAL--EEALDDfPG-TVLLVSHDRYFLDRVATRILEFEDGGVRE 509
|
|
| SufC |
COG0396 |
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ... |
7-236 |
2.84e-25 |
|
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440165 [Multi-domain] Cd Length: 245 Bit Score: 99.76 E-value: 2.84e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 7 SLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLlrcSNLL-----ELPDQGEIIVGGEAI-EMKPNrkgqnr 80
Cdd:COG0396 2 EIKNLHVSVEGKEILKGVNLTIKPGEVHAIMGPNGSGKSTL---AKVLmghpkYEVTSGSILLDGEDIlELSPD------ 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 81 psnlkqiDRIRTQLGMVFQ---------NFNLWshKTVLENIIEAPVHVLkrpqaECVEHAEQLLEKVGLAD---KRhYY 148
Cdd:COG0396 73 -------ERARAGIFLAFQypveipgvsVSNFL--RTALNARRGEELSAR-----EFLKLLKEKMKELGLDEdflDR-YV 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 149 PAHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVS-NRIVFLHQG 227
Cdd:COG0396 138 NEGFSGGEKKRNEILQMLLLEPKLAILDETDSGLDIDALRIVAEGVNKLRSPDRGILIITHYQRILDYIKpDFVHVLVDG 217
|
....*....
gi 497963481 228 EIEEQGTPE 236
Cdd:COG0396 218 RIVKSGGKE 226
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
2-229 |
2.96e-25 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 103.59 E-value: 2.96e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 2 TTPAISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAI-EMKPNrKGQnr 80
Cdd:PRK15439 8 APPLLCARSISKQYSGVEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPCaRLTPA-KAH-- 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 81 psnlkqidrirtQLG--MVFQNFNLWSHKTVLENIIeapVHVLKRPQAEcvEHAEQLLEKVGLADKRHYYPAHLSGGQQQ 158
Cdd:PRK15439 85 ------------QLGiyLVPQEPLLFPNLSVKENIL---FGLPKRQASM--QKMKQLLAALGCQLDLDSSAGSLEVADRQ 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 497963481 159 RAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEI 229
Cdd:PRK15439 148 IVEILRGLMRDSRILILDEPTASLTPAETERLFSRIRELLAQGVGIVFISHKLPEIRQLADRISVMRDGTI 218
|
|
| livF |
PRK11614 |
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF; |
1-229 |
3.59e-25 |
|
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 99.57 E-value: 3.59e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 1 MTTPAISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLrcSNLLELP--DQGEIIVGGEAIEMKPNRKgq 78
Cdd:PRK11614 1 MEKVMLSFDKVSAHYGKIQALHEVSLHINQGEIVTLIGANGAGKTTLL--GTLCGDPraTSGRIVFDGKDITDWQTAK-- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 79 nrpsnlkqidRIRTQLGMVFQNFNLWSHKTVLENIIEAPVHVLKRPQAECVEHAEQLLEKvgLADKRHYYPAHLSGGQQQ 158
Cdd:PRK11614 77 ----------IMREAVAIVPEGRRVFSRMTVEENLAMGGFFAERDQFQERIKWVYELFPR--LHERRIQRAGTMSGGEQQ 144
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 497963481 159 RAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEI 229
Cdd:PRK11614 145 MLAIGRALMSQPRLLLLDEPSLGLAPIIIQQIFDTIEQLREQGMTIFLVEQNANQALKLADRGYVLENGHV 215
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
2-223 |
3.91e-25 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 103.07 E-value: 3.91e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 2 TTPAISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEMKPNRkgqnrp 81
Cdd:PRK11288 1 SSPYLSFDGIGKTFPGVKALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGQEMRFASTT------ 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 82 snlkqiDRIRTQLGMVFQNFNLWSHKTVLENI----IEAPVHVLKRPQAecVEHAEQLLEKVGLADKRHYYPAHLSGGQQ 157
Cdd:PRK11288 75 ------AALAAGVAIIYQELHLVPEMTVAENLylgqLPHKGGIVNRRLL--NYEAREQLEHLGVDIDPDTPLKYLSIGQR 146
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 497963481 158 QRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRI-VF 223
Cdd:PRK11288 147 QMVEIAKALARNARVIAFDEPTSSLSAREIEQLFRVIRELRAEGRVILYVSHRMEEIFALCDAItVF 213
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
1-227 |
3.99e-25 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 103.33 E-value: 3.99e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 1 MTTPAISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIemkpnrkgqnr 80
Cdd:PRK09700 1 MATPYISMAGIGKSFGPVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINY----------- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 81 pSNLKQIDRIRTQLGMVFQNFNLWSHKTVLENIIEAPVHVLKR------PQAECVEHAEQLLEKVGLADKRHYYPAHLSG 154
Cdd:PRK09700 70 -NKLDHKLAAQLGIGIIYQELSVIDELTVLENLYIGRHLTKKVcgvniiDWREMRVRAAMMLLRVGLKVDLDEKVANLSI 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 497963481 155 GQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQG 227
Cdd:PRK09700 149 SHKQMLEIAKTLMLDAKVIIMDEPTSSLTNKEVDYLFLIMNQLRKEGTAIVYISHKLAEIRRICDRYTVMKDG 221
|
|
| ATM1 |
COG5265 |
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ... |
20-234 |
8.11e-25 |
|
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444078 [Multi-domain] Cd Length: 605 Bit Score: 102.59 E-value: 8.11e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 20 VLKGISIEANQGEVISILGSSGSGKSTLLRcsnLL----ElPDQGEIIVGGEAIemkpnrkgqnrpSNLKQiDRIRTQLG 95
Cdd:COG5265 373 ILKGVSFEVPAGKTVAIVGPSGAGKSTLAR---LLfrfyD-VTSGRILIDGQDI------------RDVTQ-ASLRAAIG 435
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 96 MVFQN---FNlwshKTVLENIIEApvhvlkRPQA--ECVEHAEQLlekvgladkrhyypAH------------------- 151
Cdd:COG5265 436 IVPQDtvlFN----DTIAYNIAYG------RPDAseEEVEAAARA--------------AQihdfieslpdgydtrvger 491
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 152 ---LSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLAdEGMTMLVVTHE----MDfarevSNRIVFL 224
Cdd:COG5265 492 glkLSGGEKQRVAIARTLLKNPPILIFDEATSALDSRTERAIQAALREVA-RGRTTLVIAHRlstiVD-----ADEILVL 565
|
250
....*....|
gi 497963481 225 HQGEIEEQGT 234
Cdd:COG5265 566 EAGRIVERGT 575
|
|
| 3a01208 |
TIGR00958 |
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other] |
6-234 |
1.10e-24 |
|
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 102.49 E-value: 1.10e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGS---LDVLKGISIEANQGEVISILGSSGSGKSTllrCSNLLE---LPDQGEIIVGGEAIEmkpnrkgqn 79
Cdd:TIGR00958 479 IEFQDVSFSYPNrpdVPVLKGLTFTLHPGEVVALVGPSGSGKST---VAALLQnlyQPTGGQVLLDGVPLV--------- 546
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 80 rpsnlkQIDR--IRTQLGMVFQNFNLWShKTVLENI----------------IEAPVH--VLKRPQ---AECVEHAEQll 136
Cdd:TIGR00958 547 ------QYDHhyLHRQVALVGQEPVLFS-GSVRENIaygltdtpdeeimaaaKAANAHdfIMEFPNgydTEVGEKGSQ-- 617
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 137 ekvgladkrhyypahLSGGQQQRAAIARALAMEPKVMLFDEPTSALDPElVGEVLRVMRTLADegMTMLVVTHEMDFARE 216
Cdd:TIGR00958 618 ---------------LSGGQKQRIAIARALVRKPRVLILDEATSALDAE-CEQLLQESRSRAS--RTVLLIAHRLSTVER 679
|
250
....*....|....*...
gi 497963481 217 vSNRIVFLHQGEIEEQGT 234
Cdd:TIGR00958 680 -ADQILVLKKGSVVEMGT 696
|
|
| PRK10575 |
PRK10575 |
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC; |
7-241 |
1.12e-24 |
|
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 98.71 E-value: 1.12e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 7 SLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEMKPN----RKGQNRPS 82
Cdd:PRK10575 13 ALRNVSFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSkafaRKVAYLPQ 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 83 NLKQIDrirtqlGMvfqnfnlwshkTVLE--NIIEAPVH-VLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQR 159
Cdd:PRK10575 93 QLPAAE------GM-----------TVRElvAIGRYPWHgALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQR 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 160 AAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHV 238
Cdd:PRK10575 156 AWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLALVHRLSQErGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEL 235
|
...
gi 497963481 239 FTA 241
Cdd:PRK10575 236 MRG 238
|
|
| ABC_KpsT_Wzt |
cd03220 |
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ... |
20-233 |
1.21e-24 |
|
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.
Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 97.60 E-value: 1.21e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 20 VLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGeaiemkpnrkgqnRPSNLkqIDrirtqLGMVFQ 99
Cdd:cd03220 37 ALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVTVRG-------------RVSSL--LG-----LGGGFN 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 100 NfNLwshkTVLENI-IEAPVHVLKRPQ-----AECVEHAEqlLEKVGLADKRHYypahlSGGQQQRAAIARALAMEPKVM 173
Cdd:cd03220 97 P-EL----TGRENIyLNGRLLGLSRKEidekiDEIIEFSE--LGDFIDLPVKTY-----SSGMKARLAFAIATALEPDIL 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 174 LFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQG 233
Cdd:cd03220 165 LIDEVLAVGDAAFQEKCQRRLRELLKQGKTVILVSHDPSSIKRLCDRALVLEKGKIRFDG 224
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
12-253 |
2.49e-24 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 101.47 E-value: 2.49e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 12 HKSFGSLDVLKGISIEANQGEVISILGSSGSGKS-TLLRCSNLLElpDQGEIIVGGEAIEMKPNRKG-QNRPSNLKQIDR 89
Cdd:PRK10261 23 MQEQQKIAAVRNLSFSLQRGETLAIVGESGSGKSvTALALMRLLE--QAGGLVQCDKMLLRRRSRQViELSEQSAAQMRH 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 90 IR-TQLGMVFQN--FNLWSHKTVLENIIEAPVHVLKRPQAECVEHAEQLLEKVGLADKRHY---YPAHLSGGQQQRAAIA 163
Cdd:PRK10261 101 VRgADMAMIFQEpmTSLNPVFTVGEQIAESIRLHQGASREEAMVEAKRMLDQVRIPEAQTIlsrYPHQLSGGMRQRVMIA 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 164 RALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVFTAS 242
Cdd:PRK10261 181 MALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEmSMGVIFITHDMGVVAEIADRVLVMYQGEAVETGSVEQIFHAP 260
|
250
....*....|.
gi 497963481 243 QSARFRQFIAS 253
Cdd:PRK10261 261 QHPYTRALLAA 271
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
1-228 |
4.67e-24 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 100.00 E-value: 4.67e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 1 MTTPAISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRC-SNLLELPD-QGEIIVGGEAIemkpnrkgq 78
Cdd:PRK13549 1 MMEYLLEMKNITKTFGGVKALDNVSLKVRAGEIVSLCGENGAGKSTLMKVlSGVYPHGTyEGEIIFEGEEL--------- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 79 nRPSNLKqiDRIRTQLGMVFQNFNLWSHKTVLENII--EAPVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQ 156
Cdd:PRK13549 72 -QASNIR--DTERAGIAIIHQELALVKELSVLENIFlgNEITPGGIMDYDAMYLRAQKLLAQLKLDINPATPVGNLGLGQ 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 497963481 157 QQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGE 228
Cdd:PRK13549 149 QQLVEIAKALNKQARLLILDEPTASLTESETAVLLDIIRDLKAHGIACIYISHKLNEVKAISDTICVIRDGR 220
|
|
| PRK15112 |
PRK15112 |
peptide ABC transporter ATP-binding protein SapF; |
6-253 |
5.52e-24 |
|
peptide ABC transporter ATP-binding protein SapF;
Pssm-ID: 185067 [Multi-domain] Cd Length: 267 Bit Score: 96.78 E-value: 5.52e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSF---------GSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEMKPNR- 75
Cdd:PRK15112 5 LEVRNLSKTFryrtgwfrrQTVEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLHFGDYSy 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 76 KGQnrpsnlkqidRIRtqlgMVFQN-FNLWSHKTVLENIIEAPVHVLKRPQAECVEHA-EQLLEKVGL-ADKRHYYPAHL 152
Cdd:PRK15112 85 RSQ----------RIR----MIFQDpSTSLNPRQRISQILDFPLRLNTDLEPEQREKQiIETLRQVGLlPDHASYYPHML 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 153 SGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQGEIEE 231
Cdd:PRK15112 151 APGQKQRLGLARALILRPKVIIADEALASLDMSMRSQLINLMLELQEKqGISYIYVTQHLGMMKHISDQVLVMHQGEVVE 230
|
250 260
....*....|....*....|..
gi 497963481 232 QGTPEHVFTASQSARFRQFIAS 253
Cdd:PRK15112 231 RGSTADVLASPLHELTKRLIAG 252
|
|
| MK0520 |
COG2401 |
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ... |
5-227 |
7.90e-24 |
|
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];
Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 95.41 E-value: 7.90e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 5 AISLRNIHKsfgslDVLKGISIEANQGEVISILGSSGSGKSTLLRC--SNLLELPDQGEIivggeaiEMKPNRKGQNRPs 82
Cdd:COG2401 35 GVELRVVER-----YVLRDLNLEIEPGEIVLIVGASGSGKSTLLRLlaGALKGTPVAGCV-------DVPDNQFGREAS- 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 83 nlkqidrirtqlgmvfqnfnlwshktVLENIieapvhVLKRPQAECVEhaeqLLEKVGLAD----KRHYypAHLSGGQQQ 158
Cdd:COG2401 102 --------------------------LIDAI------GRKGDFKDAVE----LLNAVGLSDavlwLRRF--KELSTGQKF 143
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 497963481 159 RAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVS-NRIVFLHQG 227
Cdd:COG2401 144 RFRLALLLAERPKLLVIDEFCSHLDRQTAKRVARNLQKLARRaGITLVVATHHYDVIDDLQpDLLIFVGYG 214
|
|
| galliderm_ABC |
TIGR03740 |
gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Model TIGR03731 ... |
9-233 |
2.47e-23 |
|
gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Model TIGR03731 represents the family of all lantibiotics related to gallidermin, including epidermin, mutatin, and nisin. This protein family describes the ATP-binding subunit of a gallidermin/epidermin class lantibiotic protection transporter. It is largely restricted to gallidermin-family lantibiotic biosynthesis and export cassettes, but also occurs in orphan transporter cassettes in species that lack candidate lantibiotic precursor and synthetase genes.
Pssm-ID: 163452 [Multi-domain] Cd Length: 223 Bit Score: 94.39 E-value: 2.47e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 9 RNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEaiemKPNRKgqnrpsNLKQId 88
Cdd:TIGR03740 4 KNLSKRFGKQTAVNNISLTVPKNSVYGLLGPNGAGKSTLLKMITGILRPTSGEIIFDGH----PWTRK------DLHKI- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 89 rirtqlGMVFQNFNLWSHKTVLENIieaPVHVLKRPQAEcvEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIARALAM 168
Cdd:TIGR03740 73 ------GSLIESPPLYENLTARENL---KVHTTLLGLPD--SRIDEVLNIVDLTNTGKKKAKQFSLGMKQRLGIAIALLN 141
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 497963481 169 EPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQG 233
Cdd:TIGR03740 142 HPKLLILDEPTNGLDPIGIQELRELIRSFPEQGITVILSSHILSEVQQLADHIGIISEGVLGYQG 206
|
|
| PRK11174 |
PRK11174 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
24-252 |
2.59e-23 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 98.38 E-value: 2.59e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 24 ISIEANQGEVISILGSSGSGKSTLLrcsNLLE--LPDQGEIIVGGeaIEmkpnrkgqnrpsnLKQIDRI--RTQLGMVFQ 99
Cdd:PRK11174 369 LNFTLPAGQRIALVGPSGAGKTSLL---NALLgfLPYQGSLKING--IE-------------LRELDPEswRKHLSWVGQ 430
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 100 NFNLWsHKTVLENIieapvhVLKRPQAEcVEHAEQLLEKVGLADKRHYYP-----------AHLSGGQQQRAAIARALAM 168
Cdd:PRK11174 431 NPQLP-HGTLRDNV------LLGNPDAS-DEQLQQALENAWVSEFLPLLPqgldtpigdqaAGLSVGQAQRLALARALLQ 502
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 169 EPKVMLFDEPTSALDpelVGEVLRVMRTL--ADEGMTMLVVTHEMDFAREVsNRIVFLHQGEIEEQGTPEHVftASQSAR 246
Cdd:PRK11174 503 PCQLLLLDEPTASLD---AHSEQLVMQALnaASRRQTTLMVTHQLEDLAQW-DQIWVMQDGQIVQQGDYAEL--SQAGGL 576
|
....*.
gi 497963481 247 FRQFIA 252
Cdd:PRK11174 577 FATLLA 582
|
|
| PRK10253 |
PRK10253 |
iron-enterobactin ABC transporter ATP-binding protein; |
1-241 |
2.99e-23 |
|
iron-enterobactin ABC transporter ATP-binding protein;
Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 95.05 E-value: 2.99e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 1 MTTPAISLR--NIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEMKPNrkgq 78
Cdd:PRK10253 1 MTESVARLRgeQLTLGYGKYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHYAS---- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 79 nrpsnlKQIDRirtQLGMVFQNFNLWSHKTVLENIIEA-----PVHVLKRPQAEcvEHAEQLLEKVGLADKRHYYPAHLS 153
Cdd:PRK10253 77 ------KEVAR---RIGLLAQNATTPGDITVQELVARGryphqPLFTRWRKEDE--EAVTKAMQATGITHLADQSVDTLS 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 154 GGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQ 232
Cdd:PRK10253 146 GGQRQRAWIAMVLAQETAIMLLDEPTTWLDISHQIDLLELLSELNREkGYTLAAVLHDLNQACRYASHLIALREGKIVAQ 225
|
....*....
gi 497963481 233 GTPEHVFTA 241
Cdd:PRK10253 226 GAPKEIVTA 234
|
|
| ABC_FeS_Assembly |
cd03217 |
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ... |
6-236 |
6.11e-23 |
|
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.
Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 92.59 E-value: 6.11e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCsnLLELPD----QGEIIVGGEAI-EMKPNrkgqnr 80
Cdd:cd03217 1 LEIKDLHVSVGGKEILKGVNLTIKKGEVHALMGPNGSGKSTLAKT--IMGHPKyevtEGEILFKGEDItDLPPE------ 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 81 psnlkqiDRIRTQLGMVFQNfnlwshktvleniieaPVHVlkrpqaecvehaeqllEKVGLADKRHYYPAHLSGGQQQRA 160
Cdd:cd03217 73 -------ERARLGIFLAFQY----------------PPEI----------------PGVKNADFLRYVNEGFSGGEKKRN 113
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 497963481 161 AIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREV-SNRIVFLHQGEIEEQGTPE 236
Cdd:cd03217 114 EILQLLLLEPDLAILDEPDSGLDIDALRLVAEVINKLREEGKSVLIITHYQRLLDYIkPDRVHVLYDGRIVKSGDKE 190
|
|
| modC |
PRK11144 |
molybdenum ABC transporter ATP-binding protein ModC; |
10-243 |
7.53e-23 |
|
molybdenum ABC transporter ATP-binding protein ModC;
Pssm-ID: 182993 [Multi-domain] Cd Length: 352 Bit Score: 95.33 E-value: 7.53e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 10 NIHKSFGSLDVLKGISIEANqgEVISILGSSGSGKSTLLrcsNL---LELPDQGEIIVGGEAieMKPNRKGQNRPSNLKQ 86
Cdd:PRK11144 5 NFKQQLGDLCLTVNLTLPAQ--GITAIFGRSGAGKTSLI---NAisgLTRPQKGRIVLNGRV--LFDAEKGICLPPEKRR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 87 IdrirtqlGMVFQNFNLWSHKTVLENIIEAPVHVLKrpqaecvEHAEQLLEKVGLAD--KRhyYPAHLSGGQQQRAAIAR 164
Cdd:PRK11144 78 I-------GYVFQDARLFPHYKVRGNLRYGMAKSMV-------AQFDKIVALLGIEPllDR--YPGSLSGGEKQRVAIGR 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 165 ALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVFTASQ 243
Cdd:PRK11144 142 ALLTAPELLLMDEPLASLDLPRKRELLPYLERLAREiNIPILYVSHSLDEILRLADRVVVLEQGKVKAFGPLEEVWASSA 221
|
|
| ABCC_MRP_domain2 |
cd03244 |
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ... |
20-235 |
1.36e-22 |
|
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 92.17 E-value: 1.36e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 20 VLKGISIEANQGEVISILGSSGSGKSTLLrcSNLLEL--PDQGEIIVGGEaiemkpnrkgqnrpsNLKQIDR--IRTQLG 95
Cdd:cd03244 19 VLKNISFSIKPGEKVGIVGRTGSGKSSLL--LALFRLveLSSGSILIDGV---------------DISKIGLhdLRSRIS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 96 MVFQNFNLWShKTVLENIieapvhvlkRPQAECVEHA-EQLLEKVGLADKRHYYP-----------AHLSGGQQQRAAIA 163
Cdd:cd03244 82 IIPQDPVLFS-GTIRSNL---------DPFGEYSDEElWQALERVGLKEFVESLPggldtvveeggENLSVGQRQLLCLA 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 497963481 164 RALAMEPKVMLFDEPTSALDPELVGEVLRVMRTlADEGMTMLVVTHE----MDfarevSNRIVFLHQGEIEEQGTP 235
Cdd:cd03244 152 RALLRKSKILVLDEATASVDPETDALIQKTIRE-AFKDCTVLTIAHRldtiID-----SDRILVLDKGRVVEFDSP 221
|
|
| PRK13657 |
PRK13657 |
glucan ABC transporter ATP-binding protein/ permease; |
5-234 |
2.71e-22 |
|
glucan ABC transporter ATP-binding protein/ permease;
Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 95.41 E-value: 2.71e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 5 AISLRNIHKSF-GSLDVLKGISIEANQGEVISILGSSGSGKSTLLrcsNLLEL---PDQGEIIVGGEAIemkpnrKGQNR 80
Cdd:PRK13657 334 AVEFDDVSFSYdNSRQGVEDVSFEAKPGQTVAIVGPTGAGKSTLI---NLLQRvfdPQSGRILIDGTDI------RTVTR 404
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 81 PSnlkqidrIRTQLGMVFQN---FNlwshKTVLENI-------IEAPVH-VLKRPQA-ECVEHAEQLLEKVglADKRHyy 148
Cdd:PRK13657 405 AS-------LRRNIAVVFQDaglFN----RSIEDNIrvgrpdaTDEEMRaAAERAQAhDFIERKPDGYDTV--VGERG-- 469
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 149 pAHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLAdEGMTMLVVTHEMDFAREvSNRIVFLHQGE 228
Cdd:PRK13657 470 -RQLSGGERQRLAIARALLKDPPILILDEATSALDVETEAKVKAALDELM-KGRTTFIIAHRLSTVRN-ADRILVFDNGR 546
|
....*.
gi 497963481 229 IEEQGT 234
Cdd:PRK13657 547 VVESGS 552
|
|
| ArpD |
COG4618 |
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ... |
20-246 |
3.20e-22 |
|
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 443660 [Multi-domain] Cd Length: 563 Bit Score: 95.20 E-value: 3.20e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 20 VLKGISIEANQGEVISILGSSGSGKSTLLRCsnLLEL--PDQGEIIVGGeaiemkpnrkgqnrpSNLKQIDRirTQLGMV 97
Cdd:COG4618 347 ILRGVSFSLEPGEVLGVIGPSGSGKSTLARL--LVGVwpPTAGSVRLDG---------------ADLSQWDR--EELGRH 407
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 98 F----QNFNLWShKTVLENI-----------IEAP----VH--VLKRPQAecvehaeqllekvgladkrhyY-------P 149
Cdd:COG4618 408 IgylpQDVELFD-GTIAENIarfgdadpekvVAAAklagVHemILRLPDG---------------------YdtrigegG 465
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 150 AHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDPElvGE--VLRVMRTLADEGMTMLVVTHEMDFAREVsNRIVFLHQG 227
Cdd:COG4618 466 ARLSGGQRQRIGLARALYGDPRLVVLDEPNSNLDDE--GEaaLAAAIRALKARGATVVVITHRPSLLAAV-DKLLVLRDG 542
|
250
....*....|....*....
gi 497963481 228 EIEEQGTPEHVFTASQSAR 246
Cdd:COG4618 543 RVQAFGPRDEVLARLARPA 561
|
|
| ABCC_TAP |
cd03248 |
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ... |
20-229 |
3.25e-22 |
|
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.
Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 91.38 E-value: 3.25e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 20 VLKGISIEANQGEVISILGSSGSGKSTllrCSNLLE---LPDQGEIIVGGEAIEMKPNRkgqnrpsnlkqidRIRTQLGM 96
Cdd:cd03248 29 VLQDVSFTLHPGEVTALVGPSGSGKST---VVALLEnfyQPQGGQVLLDGKPISQYEHK-------------YLHSKVSL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 97 VFQNFNLWShKTVLENIieapVHVLKRPQAECVEHAEQ---------LLEKvGLADKRHYYPAHLSGGQQQRAAIARALA 167
Cdd:cd03248 93 VGQEPVLFA-RSLQDNI----AYGLQSCSFECVKEAAQkahahsfisELAS-GYDTEVGEKGSQLSGGQKQRVAIARALI 166
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 497963481 168 MEPKVMLFDEPTSALDPELVGEVLRVMRTlADEGMTMLVVTHEMDFArEVSNRIVFLHQGEI 229
Cdd:cd03248 167 RNPQVLILDEATSALDAESEQQVQQALYD-WPERRTVLVIAHRLSTV-ERADQILVLDGGRI 226
|
|
| PRK15056 |
PRK15056 |
manganese/iron ABC transporter ATP-binding protein; |
6-246 |
2.05e-21 |
|
manganese/iron ABC transporter ATP-binding protein;
Pssm-ID: 185016 [Multi-domain] Cd Length: 272 Bit Score: 90.33 E-value: 2.05e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSfgsldvLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIivggeAIEMKPNRKG--QNRPSN 83
Cdd:PRK15056 14 VTWRNGHTA------LRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKI-----SILGQPTRQAlqKNLVAY 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 84 LKQIDRIRtqlgmvfqnfnlWSHKTVLENIIE----APVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQR 159
Cdd:PRK15056 83 VPQSEEVD------------WSFPVLVEDVVMmgryGHMGWLRRAKKRDRQIVTAALARVDMVEFRHRQIGELSGGQKKR 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 160 AAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLhQGEIEEQGTPEHVF 239
Cdd:PRK15056 151 VFLARAIAQQGQVILLDEPFTGVDVKTEARIISLLRELRDEGKTMLVSTHNLGSVTEFCDYTVMV-KGTVLASGPTETTF 229
|
....*..
gi 497963481 240 TASQSAR 246
Cdd:PRK15056 230 TAENLEL 236
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
4-229 |
3.59e-21 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 92.01 E-value: 3.59e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 4 PAISLRNIH-KSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLR-CSNLLElPDQGEIIVGGEAIEMKPNRKGQNR- 80
Cdd:COG3845 256 VVLEVENLSvRDDRGVPALKDVSLEVRAGEILGIAGVAGNGQSELAEaLAGLRP-PASGSIRLDGEDITGLSPRERRRLg 334
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 81 ----PSnlkqiDRIRTqlGMVfQNFNLWSHkTVLENIIEAPVH---VLKRPQAEcvEHAEQLLEKVGLADKRHYYPA-HL 152
Cdd:COG3845 335 vayiPE-----DRLGR--GLV-PDMSVAEN-LILGRYRRPPFSrggFLDRKAIR--AFAEELIEEFDVRTPGPDTPArSL 403
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 153 SGGQQQRAAIARALAMEPKVMLFDEPTSALDpelVG---EVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEI 229
Cdd:COG3845 404 SGGNQQKVILARELSRDPKLLIAAQPTRGLD---VGaieFIHQRLLELRDAGAAVLLISEDLDEILALSDRIAVMYEGRI 480
|
|
| ccmA |
TIGR01189 |
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ... |
6-209 |
4.69e-21 |
|
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]
Pssm-ID: 273491 [Multi-domain] Cd Length: 198 Bit Score: 87.41 E-value: 4.69e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIemkpnrkGQNRPSNLK 85
Cdd:TIGR01189 1 LAARNLACSRGERMLFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPL-------AEQRDEPHE 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 86 QI------DRIRTQLgmvfqnfnlwshkTVLENIieapvHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQR 159
Cdd:TIGR01189 74 NIlylghlPGLKPEL-------------SALENL-----HFWAAIHGGAQRTIEDALAAVGLTGFEDLPAAQLSAGQQRR 135
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 497963481 160 AAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTH 209
Cdd:TIGR01189 136 LALARLWLSRRPLWILDEPTTALDKAGVALLAGLLRAHLARGGIVLLTTH 185
|
|
| nikD |
PRK10418 |
nickel transporter ATP-binding protein NikD; Provisional |
22-253 |
4.74e-21 |
|
nickel transporter ATP-binding protein NikD; Provisional
Pssm-ID: 236688 [Multi-domain] Cd Length: 254 Bit Score: 88.99 E-value: 4.74e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 22 KGISIEANQGEVISILGSSGSGKStlLRCSNLLE-LP-----DQGEIIVGGEAIEmkpnrkgqnrPSNLkqidRIRTqLG 95
Cdd:PRK10418 20 HGVSLTLQRGRVLALVGGSGSGKS--LTCAAALGiLPagvrqTAGRVLLDGKPVA----------PCAL----RGRK-IA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 96 MVFQN----FN----LWSH--KTVLENIIEAPVHVLkrpqAECvehaeqlLEKVGLADKR---HYYPAHLSGGQQQRAAI 162
Cdd:PRK10418 83 TIMQNprsaFNplhtMHTHarETCLALGKPADDATL----TAA-------LEAVGLENAArvlKLYPFEMSGGMLQRMMI 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 163 ARALAMEPKVMLFDEPTSALDPELVGEVLR-VMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVFTA 241
Cdd:PRK10418 152 ALALLCEAPFIIADEPTTDLDVVAQARILDlLESIVQKRALGMLLVTHDMGVVARLADDVAVMSHGRIVEQGDVETLFNA 231
|
250
....*....|..
gi 497963481 242 SQSARFRQFIAS 253
Cdd:PRK10418 232 PKHAVTRSLVSA 243
|
|
| PRK10247 |
PRK10247 |
putative ABC transporter ATP-binding protein YbbL; Provisional |
3-231 |
4.79e-21 |
|
putative ABC transporter ATP-binding protein YbbL; Provisional
Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 88.23 E-value: 4.79e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 3 TPAISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAI-EMKPnrkgqnrp 81
Cdd:PRK10247 5 SPLLQLQNVGYLAGDAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDIsTLKP-------- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 82 snlkqiDRIRTQLGMVFQNFNLWShKTVLENIIeAPVHVlkRPQAECVEHAEQLLEKVGLADKRHYYP-AHLSGGQQQRA 160
Cdd:PRK10247 77 ------EIYRQQVSYCAQTPTLFG-DTVYDNLI-FPWQI--RNQQPDPAIFLDDLERFALPDTILTKNiAELSGGEKQRI 146
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 497963481 161 AIARALAMEPKVMLFDEPTSALDP---ELVGEVlrVMRTLADEGMTMLVVTHEMDFAREVSNRIVFL-HQGEIEE 231
Cdd:PRK10247 147 SLIRNLQFMPKVLLLDEITSALDEsnkHNVNEI--IHRYVREQNIAVLWVTHDKDEINHADKVITLQpHAGEMQE 219
|
|
| oppD |
PRK09473 |
oligopeptide transporter ATP-binding component; Provisional |
29-239 |
6.53e-21 |
|
oligopeptide transporter ATP-binding component; Provisional
Pssm-ID: 181888 [Multi-domain] Cd Length: 330 Bit Score: 89.78 E-value: 6.53e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 29 NQGEVISILGSSGSGKS-TLLRCSNLLelPDQGeiIVGGEAiemKPN-RKGQNRPSnlKQIDRIRT-QLGMVFQN--FNL 103
Cdd:PRK09473 40 RAGETLGIVGESGSGKSqTAFALMGLL--AANG--RIGGSA---TFNgREILNLPE--KELNKLRAeQISMIFQDpmTSL 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 104 WSHKTVLENIIEapVHVLKR--PQAECVEHAEQLLEKVGL--ADKR-HYYPAHLSGGQQQRAAIARALAMEPKVMLFDEP 178
Cdd:PRK09473 111 NPYMRVGEQLME--VLMLHKgmSKAEAFEESVRMLDAVKMpeARKRmKMYPHEFSGGMRQRVMIAMALLCRPKLLIADEP 188
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 497963481 179 TSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVF 239
Cdd:PRK09473 189 TTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGNARDVF 250
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
6-228 |
7.38e-21 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 91.04 E-value: 7.38e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLR--CSNLLELPDQGEIIVGGEAIEMKPNRkgqnrpsn 83
Cdd:TIGR02633 2 LEMKGIVKTFGGVKALDGIDLEVRPGECVGLCGENGAGKSTLMKilSGVYPHGTWDGEIYWSGSPLKASNIR-------- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 84 lkqiDRIRTQLGMVFQNFNLWSHKTVLENII---EAPVHVLKRPQAECVEHAEQLLEKVGLADKRHYYP-AHLSGGQQQR 159
Cdd:TIGR02633 74 ----DTERAGIVIIHQELTLVPELSVAENIFlgnEITLPGGRMAYNAMYLRAKNLLRELQLDADNVTRPvGDYGGGQQQL 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 497963481 160 AAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGE 228
Cdd:TIGR02633 150 VEIAKALNKQARLLILDEPSSSLTEKETEILLDIIRDLKAHGVACVYISHKLNEVKAVCDTICVIRDGQ 218
|
|
| ABCF_EF-3 |
cd03221 |
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ... |
6-228 |
9.84e-21 |
|
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.
Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 85.19 E-value: 9.84e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGgeaiemkpnrkgqnrpsnlk 85
Cdd:cd03221 1 IELENLSKTYGGKLLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIVTWG-------------------- 60
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 86 qidrirtqlgmvfqnfnlwshktvleniieapvhvlkrpqaecvehaeqllekvglADKRHYYPAHLSGGQQQRAAIARA 165
Cdd:cd03221 61 --------------------------------------------------------STVKIGYFEQLSGGEKMRLALAKL 84
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 497963481 166 LAMEPKVMLFDEPTSALDPELVgEVLRvmRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGE 228
Cdd:cd03221 85 LLENPNLLLLDEPTNHLDLESI-EALE--EALKEYPGTVILVSHDRYFLDQVATKIIELEDGK 144
|
|
| ABC_NatA_like |
cd03267 |
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ... |
7-233 |
1.46e-20 |
|
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.
Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 87.00 E-value: 1.46e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 7 SLRNI-HKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGeaiemkpnrkgqNRPSnlK 85
Cdd:cd03267 22 SLKSLfKRKYREVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVAG------------LVPW--K 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 86 QIDRIRTQLGMVF-QNFNLWSHKTVLENIiEAPVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIAR 164
Cdd:cd03267 88 RRKKFLRRIGVVFgQKTQLWWDLPVIDSF-YLLAAIYDLPPARFKKRLDELSELLDLEELLDTPVRQLSLGQRMRAEIAA 166
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 165 ALAMEPKVMLFDEPTSALDPELVGEVLRVMRTL-ADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQG 233
Cdd:cd03267 167 ALLHEPEILFLDEPTIGLDVVAQENIRNFLKEYnRERGTTVLLTSHYMKDIEALARRVLVIDKGRLLYDG 236
|
|
| BtuD |
COG4138 |
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ... |
21-241 |
1.73e-20 |
|
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];
Pssm-ID: 443313 [Multi-domain] Cd Length: 248 Bit Score: 87.20 E-value: 1.73e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 21 LKGISIEANQGEVISILGSSGSGKSTLL-RCSNLleLPDQGEIIVGGEAI-EMKPNRKGQNRpSNLKQidRIRTQLGM-V 97
Cdd:COG4138 12 LGPISAQVNAGELIHLIGPNGAGKSTLLaRMAGL--LPGQGEILLNGRPLsDWSAAELARHR-AYLSQ--QQSPPFAMpV 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 98 FQNFNLwshktvleniieapvHVLKRPQAECVEHA-EQLLEKVGLADKRHYYPAHLSGGQQQRAAIARALAM-------E 169
Cdd:COG4138 87 FQYLAL---------------HQPAGASSEAVEQLlAQLAEALGLEDKLSRPLTQLSGGEWQRVRLAAVLLQvwptinpE 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 497963481 170 PKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVFTA 241
Cdd:COG4138 152 GQLLLLDEPMNSLDVAQQAALDRLLRELCQQGITVVMSSHDLNHTLRHADRVWLLKQGKLVASGETAEVMTP 223
|
|
| PRK11176 |
PRK11176 |
lipid A ABC transporter ATP-binding protein/permease MsbA; |
21-234 |
6.97e-20 |
|
lipid A ABC transporter ATP-binding protein/permease MsbA;
Pssm-ID: 183016 [Multi-domain] Cd Length: 582 Bit Score: 88.15 E-value: 6.97e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 21 LKGISIEANQGEVISILGSSGSGKSTLlrcSNLLEL---PDQGEIIVGGEAIEmkpnrkgQNRPSNLkqidriRTQLGMV 97
Cdd:PRK11176 359 LRNINFKIPAGKTVALVGRSGSGKSTI---ANLLTRfydIDEGEILLDGHDLR-------DYTLASL------RNQVALV 422
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 98 FQNFNLWShKTVLENIIEAPVHVLKRPQ---AECVEHAEQLLEKV--GLADKRHYYPAHLSGGQQQRAAIARALAMEPKV 172
Cdd:PRK11176 423 SQNVHLFN-DTIANNIAYARTEQYSREQieeAARMAYAMDFINKMdnGLDTVIGENGVLLSGGQRQRIAIARALLRDSPI 501
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 497963481 173 MLFDEPTSALDPElvGEvlRVMRTLADE---GMTMLVVTHEMDfAREVSNRIVFLHQGEIEEQGT 234
Cdd:PRK11176 502 LILDEATSALDTE--SE--RAIQAALDElqkNRTSLVIAHRLS-TIEKADEILVVEDGEIVERGT 561
|
|
| type_I_sec_PrtD |
TIGR01842 |
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ... |
16-241 |
1.73e-19 |
|
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 200134 [Multi-domain] Cd Length: 544 Bit Score: 87.02 E-value: 1.73e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 16 GSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGeaiemkpnrkgqnrpSNLKQIDR--IRTQ 93
Cdd:TIGR01842 329 GKKPTLRGISFSLQAGEALAIIGPSGSGKSTLARLIVGIWPPTSGSVRLDG---------------ADLKQWDRetFGKH 393
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 94 LGMVFQNFNLWShKTVLENI------------IEAP----VH--VLKRPQAECVEhaeqllekVGLADkrhyypAHLSGG 155
Cdd:TIGR01842 394 IGYLPQDVELFP-GTVAENIarfgenadpekiIEAAklagVHelILRLPDGYDTV--------IGPGG------ATLSGG 458
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 156 QQQRAAIARALAMEPKVMLFDEPTSALDPElvGE--VLRVMRTLADEGMTMLVVTHEMDfAREVSNRIVFLHQGEIEEQG 233
Cdd:TIGR01842 459 QRQRIALARALYGDPKLVVLDEPNSNLDEE--GEqaLANAIKALKARGITVVVITHRPS-LLGCVDKILVLQDGRIARFG 535
|
....*...
gi 497963481 234 TPEHVFTA 241
Cdd:TIGR01842 536 ERDEVLAK 543
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
2-232 |
1.99e-19 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 86.98 E-value: 1.99e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 2 TTPAISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEMKPNRKGQnrp 81
Cdd:PRK10762 1 MQALLQLKGIDKAFPGVKALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSILYLGKEVTFNGPKSSQ--- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 82 snlkqidriRTQLGMVFQNFNLWSHKTVLENII--EAPVHVLKRPQ-AECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQ 158
Cdd:PRK10762 78 ---------EAGIGIIHQELNLIPQLTIAENIFlgREFVNRFGRIDwKKMYAEADKLLARLNLRFSSDKLVGELSIGEQQ 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 497963481 159 RAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGE-IEEQ 232
Cdd:PRK10762 149 MVEIAKVLSFESKVIIMDEPTDALTDTETESLFRVIRELKSQGRGIVYISHRLKEIFEICDDVTVFRDGQfIAER 223
|
|
| bacteriocin_ABC |
TIGR01193 |
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ... |
15-234 |
3.14e-19 |
|
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]
Pssm-ID: 130261 [Multi-domain] Cd Length: 708 Bit Score: 86.72 E-value: 3.14e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 15 FGSlDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGeaiemkpnrkgqnrpSNLKQIDR--IRT 92
Cdd:TIGR01193 485 YGS-NILSDISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQARSGEILLNG---------------FSLKDIDRhtLRQ 548
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 93 QLGMVFQNFNLWShKTVLEN-IIEAPVHVLKRPQAECVEHAE--QLLEKV--GLADKRHYYPAHLSGGQQQRAAIARALA 167
Cdd:TIGR01193 549 FINYLPQEPYIFS-GSILENlLLGAKENVSQDEIWAACEIAEikDDIENMplGYQTELSEEGSSISGGQKQRIALARALL 627
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 497963481 168 MEPKVMLFDEPTSALDPELVGEVLRVMRTLADEgmTMLVVTHEMDFAREvSNRIVFLHQGEIEEQGT 234
Cdd:TIGR01193 628 TDSKVLILDESTSNLDTITEKKIVNNLLNLQDK--TIIFVAHRLSVAKQ-SDKIIVLDHGKIIEQGS 691
|
|
| ABC_CcmA_heme_exporter |
cd03231 |
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ... |
16-209 |
4.16e-19 |
|
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.
Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 82.54 E-value: 4.16e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 16 GSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIvggeaieMKPNRKGQNRPSNLKQIDRIRTQLG 95
Cdd:cd03231 11 DGRALFSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVL-------LNGGPLDFQRDSIARGLLYLGHAPG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 96 MvfqnfnlwshKTVLeniieAPVHVLKRPQAEC-VEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIARALAMEPKVML 174
Cdd:cd03231 84 I----------KTTL-----SVLENLRFWHADHsDEQVEEALARVGLNGFEDRPVAQLSAGQQRRVALARLLLSGRPLWI 148
|
170 180 190
....*....|....*....|....*....|....*
gi 497963481 175 FDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTH 209
Cdd:cd03231 149 LDEPTTALDKAGVARFAEAMAGHCARGGMVVLTTH 183
|
|
| PRK13539 |
PRK13539 |
cytochrome c biogenesis protein CcmA; Provisional |
20-217 |
1.20e-18 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 81.07 E-value: 1.20e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 20 VLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEmkpnrkgqnrpsnlkqIDRIRTQ---LGm 96
Cdd:PRK13539 17 LFSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGDID----------------DPDVAEAchyLG- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 97 vFQNFnLWSHKTVLENIiEAPVHVLKRPQAEcVEHAeqlLEKVGLADKRHYYPAHLSGGQQQRAAIARALAMEPKVMLFD 176
Cdd:PRK13539 80 -HRNA-MKPALTVAENL-EFWAAFLGGEELD-IAAA---LEAVGLAPLAHLPFGYLSAGQKRRVALARLLVSNRPIWILD 152
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 497963481 177 EPTSALDPELVGEVLRVMRTLADEGMTMLVVTH---EMDFAREV 217
Cdd:PRK13539 153 EPTAALDAAAVALFAELIRAHLAQGGIVIAATHiplGLPGAREL 196
|
|
| COG4586 |
COG4586 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
5-229 |
1.70e-18 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443643 [Multi-domain] Cd Length: 323 Bit Score: 82.83 E-value: 1.70e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 5 AISLRNIHKSF----------GSL-----------DVLKGISIEANQGEVISILGSSGSGKSTLLRC-SNLLElPDQGEI 62
Cdd:COG4586 1 IIEVENLSKTYrvyekepglkGALkglfrreyrevEAVDDISFTIEPGEIVGFIGPNGAGKSTTIKMlTGILV-PTSGEV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 63 IVGGeaieMKPNRkgqNRPSNLKQIdrirtqlGMVF-QNFNLWSHKTVLEN------IIEAPVHVLKRPQAECVEhaeqL 135
Cdd:COG4586 80 RVLG----YVPFK---RRKEFARRI-------GVVFgQRSQLWWDLPAIDSfrllkaIYRIPDAEYKKRLDELVE----L 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 136 LEKVGLADKrhyyPA-HLSGGQQQRAAIARALAMEPKVMLFDEPTSALDP---ELVGEVLRVMRtlADEGMTMLVVTHEM 211
Cdd:COG4586 142 LDLGELLDT----PVrQLSLGQRMRCELAAALLHRPKILFLDEPTIGLDVvskEAIREFLKEYN--RERGTTILLTSHDM 215
|
250
....*....|....*...
gi 497963481 212 DFAREVSNRIVFLHQGEI 229
Cdd:COG4586 216 DDIEALCDRVIVIDHGRI 233
|
|
| SapD |
COG4170 |
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms]; |
16-241 |
6.89e-18 |
|
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
Pssm-ID: 443330 [Multi-domain] Cd Length: 331 Bit Score: 81.49 E-value: 6.89e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 16 GSLDVLKGISIEANQGEVISILGSSGSGKStlLRCSNLLELPDQGEIIV-------GGEAIEMKPNRKgqnrpsnlKQId 88
Cdd:COG4170 18 GRVKAVDRVSLTLNEGEIRGLVGESGSGKS--LIAKAICGITKDNWHVTadrfrwnGIDLLKLSPRER--------RKI- 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 89 rIRTQLGMVFQNFN--LWSHKTVLENIIEA-PVHVLK-----RPQAEcVEHAEQLLEKVGLADKRHY---YPAHLSGGQQ 157
Cdd:COG4170 87 -IGREIAMIFQEPSscLDPSAKIGDQLIEAiPSWTFKgkwwqRFKWR-KKRAIELLHRVGIKDHKDImnsYPHELTEGEC 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 158 QRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLAD-EGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPE 236
Cdd:COG4170 165 QKVMIAMAIANQPRLLIADEPTNAMESTTQAQIFRLLARLNQlQGTSILLISHDLESISQWADTITVLYCGQTVESGPTE 244
|
....*
gi 497963481 237 HVFTA 241
Cdd:COG4170 245 QILKS 249
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
22-231 |
7.40e-18 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 82.14 E-value: 7.40e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 22 KGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEaiEMKPNRKGQNRPSNLKQIDRIRTQLGMvFQNF 101
Cdd:PRK09700 280 RDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGK--DISPRSPLDAVKKGMAYITESRRDNGF-FPNF 356
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 102 NLWSHKTVLENIIEAPvhvLKRPQAECVEHAEQLL---EKVGLADKRHYYPAH---LSGGQQQRAAIARALAMEPKVMLF 175
Cdd:PRK09700 357 SIAQNMAISRSLKDGG---YKGAMGLFHEVDEQRTaenQRELLALKCHSVNQNiteLSGGNQQKVLISKWLCCCPEVIIF 433
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 497963481 176 DEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEE 231
Cdd:PRK09700 434 DEPTRGIDVGAKAEIYKVMRQLADDGKVILMVSSELPEIITVCDRIAVFCEGRLTQ 489
|
|
| PRK15093 |
PRK15093 |
peptide ABC transporter ATP-binding protein SapD; |
4-241 |
6.36e-17 |
|
peptide ABC transporter ATP-binding protein SapD;
Pssm-ID: 185049 [Multi-domain] Cd Length: 330 Bit Score: 78.69 E-value: 6.36e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 4 PAISLRNIHKSF----GSLDVLKGISIEANQGEVISILGSSGSGKSTLLR--CS------------------NLLELPDQ 59
Cdd:PRK15093 2 PLLDIRNLTIEFktsdGWVKAVDRVSMTLTEGEIRGLVGESGSGKSLIAKaiCGvtkdnwrvtadrmrfddiDLLRLSPR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 60 GEIIVGGEAIEMKpnrkGQNRPSNLKQIDRIRTQLgmvFQNFNLWSHKTVLENIieapVHVLKRpqaecveHAEQLLEKV 139
Cdd:PRK15093 82 ERRKLVGHNVSMI----FQEPQSCLDPSERVGRQL---MQNIPGWTYKGRWWQR----FGWRKR-------RAIELLHRV 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 140 GLADKR---HYYPAHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTL-ADEGMTMLVVTHEMDFAR 215
Cdd:PRK15093 144 GIKDHKdamRSFPYELTEGECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLTRLnQNNNTTILLISHDLQMLS 223
|
250 260
....*....|....*....|....*.
gi 497963481 216 EVSNRIVFLHQGEIEEQGTPEHVFTA 241
Cdd:PRK15093 224 QWADKINVLYCGQTVETAPSKELVTT 249
|
|
| PRK03695 |
PRK03695 |
vitamin B12-transporter ATPase; Provisional |
24-246 |
7.33e-17 |
|
vitamin B12-transporter ATPase; Provisional
Pssm-ID: 235150 [Multi-domain] Cd Length: 248 Bit Score: 77.28 E-value: 7.33e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 24 ISIEANQGEVISILGSSGSGKSTLLRCSNLLeLPDQGEIIVGGEAIEMKPNRKGQNRPSNLKQidRIRTQLGM-VFQNFN 102
Cdd:PRK03695 15 LSAEVRAGEILHLVGPNGAGKSTLLARMAGL-LPGSGSIQFAGQPLEAWSAAELARHRAYLSQ--QQTPPFAMpVFQYLT 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 103 LwshktvleniieapvHVLKRPQAECVEHA-EQLLEKVGLADKRHYYPAHLSGGQQQR---AA----IARALAMEPKVML 174
Cdd:PRK03695 92 L---------------HQPDKTRTEAVASAlNEVAEALGLDDKLGRSVNQLSGGEWQRvrlAAvvlqVWPDINPAGQLLL 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 497963481 175 FDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVFTASQSAR 246
Cdd:PRK03695 157 LDEPMNSLDVAQQAALDRLLSELCQQGIAVVMSSHDLNHTLRHADRVWLLKQGKLLASGRRDEVLTPENLAQ 228
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
8-228 |
7.75e-17 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 79.39 E-value: 7.75e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 8 LRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEMKPNRKGqnrpsnlkqi 87
Cdd:PRK10982 1 MSNISKSFPGVKALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQGKEIDFKSSKEA---------- 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 88 drIRTQLGMVFQNFNLWSHKTVLENII--EAPVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIARA 165
Cdd:PRK10982 71 --LENGISMVHQELNLVLQRSVMDNMWlgRYPTKGMFVDQDKMYRDTKAIFDELDIDIDPRAKVATLSVSQMQMIEIAKA 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 497963481 166 LAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGE 228
Cdd:PRK10982 149 FSYNAKIVIMDEPTSSLTEKEVNHLFTIIRKLKERGCGIVYISHKMEEIFQLCDEITILRDGQ 211
|
|
| PRK10789 |
PRK10789 |
SmdA family multidrug ABC transporter permease/ATP-binding protein; |
5-248 |
1.04e-16 |
|
SmdA family multidrug ABC transporter permease/ATP-binding protein;
Pssm-ID: 182732 [Multi-domain] Cd Length: 569 Bit Score: 78.99 E-value: 1.04e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 5 AISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLrcSNLLELPD--QGEIivggeaiemkpnrKGQNRPS 82
Cdd:PRK10789 315 DVNIRQFTYPQTDHPALENVNFTLKPGQMLGICGPTGSGKSTLL--SLIQRHFDvsEGDI-------------RFHDIPL 379
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 83 NLKQIDRIRTQLGMVFQNFNLWShKTVLENIieapvhVLKRPQA--ECVEHAEQL--------------LEKVGladKRH 146
Cdd:PRK10789 380 TKLQLDSWRSRLAVVSQTPFLFS-DTVANNI------ALGRPDAtqQEIEHVARLasvhddilrlpqgyDTEVG---ERG 449
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 147 yypAHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLAdEGMTMLVVTHEMDFAREVSNrIVFLHQ 226
Cdd:PRK10789 450 ---VMLSGGQKQRISIARALLLNAEILILDDALSAVDGRTEHQILHNLRQWG-EGRTVIISAHRLSALTEASE-ILVMQH 524
|
250 260
....*....|....*....|..
gi 497963481 227 GEIEEQGTPEHVftASQSARFR 248
Cdd:PRK10789 525 GHIAQRGNHDQL--AQQSGWYR 544
|
|
| ABCC_MRP_domain1 |
cd03250 |
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ... |
20-228 |
1.38e-16 |
|
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 75.58 E-value: 1.38e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 20 VLKGISIEANQGEVISILGSSGSGKSTLLRCsnLL-ELP-DQGEIIVGGeaiemkpnrkgqnrpsnlkqidrirtQLGMV 97
Cdd:cd03250 20 TLKDINLEVPKGELVAIVGPVGSGKSSLLSA--LLgELEkLSGSVSVPG--------------------------SIAYV 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 98 FQN---FNLwshkTVLENIIEApvHVLKRPQAECVEHAEQLL---------------EKvGLAdkrhyypahLSGGQQQR 159
Cdd:cd03250 72 SQEpwiQNG----TIRENILFG--KPFDEERYEKVIKACALEpdleilpdgdlteigEK-GIN---------LSGGQKQR 135
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 497963481 160 AAIARALAMEPKVMLFDEPTSALDPElVGEVL--RVMRTLADEGMTMLVVTHEMDFAREVsNRIVFLHQGE 228
Cdd:cd03250 136 ISLARAVYSDADIYLLDDPLSAVDAH-VGRHIfeNCILGLLLNNKTRILVTHQLQLLPHA-DQIVVLDNGR 204
|
|
| ABC_RNaseL_inhibitor_domain2 |
cd03237 |
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
17-234 |
2.33e-16 |
|
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 75.91 E-value: 2.33e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 17 SLDVLKGisiEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEMKPNrkgQNRPsnlKQIDRIRTQLGM 96
Cdd:cd03237 14 TLEVEGG---SISESEVIGILGPNGIGKTTFIKMLAGVLKPDEGDIEIELDTVSYKPQ---YIKA---DYEGTVRDLLSS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 97 VFQNFNLWSHktvLENIIEAPVHVlkrpqaecvehaEQLLEKVGLadkrhyypaHLSGGQQQRAAIARALAMEPKVMLFD 176
Cdd:cd03237 85 ITKDFYTHPY---FKTEIAKPLQI------------EQILDREVP---------ELSGGELQRVAIAACLSKDADIYLLD 140
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 177 EPTSALDPELVGEVLRVMRTLADEG-MTMLVVTHEMDFAREVSNR-IVFlhQGEIEEQGT 234
Cdd:cd03237 141 EPSAYLDVEQRLMASKVIRRFAENNeKTAFVVEHDIIMIDYLADRlIVF--EGEPSVNGV 198
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
4-252 |
3.82e-16 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 77.47 E-value: 3.82e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 4 PAISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKST---LLrcSNLLElPDQGEIIVGGEAIEmkpnrkgqnr 80
Cdd:NF033858 265 PAIEARGLTMRFGDFTAVDHVSFRIRRGEIFGFLGSNGCGKSTtmkML--TGLLP-ASEGEAWLFGQPVD---------- 331
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 81 PSNLKqidrIRTQLGMVFQNFNLWSHKTVLENIieapvhVL-----KRPQAECVEHAEQLLEKVGLADKRHYYPAHLSGG 155
Cdd:NF033858 332 AGDIA----TRRRVGYMSQAFSLYGELTVRQNL------ELharlfHLPAAEIAARVAEMLERFDLADVADALPDSLPLG 401
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 156 QQQRAAIARALAMEPKVMLFDEPTSALDPelvgeVLRVM--RTLAD----EGMTMLVVTHEMDFArEVSNRIVFLHQGEI 229
Cdd:NF033858 402 IRQRLSLAVAVIHKPELLILDEPTSGVDP-----VARDMfwRLLIElsreDGVTIFISTHFMNEA-ERCDRISLMHAGRV 475
|
250 260
....*....|....*....|....
gi 497963481 230 EEQGTPEHVFTASQSARFRQ-FIA 252
Cdd:NF033858 476 LASDTPAALVAARGAATLEEaFIA 499
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
8-227 |
5.15e-16 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 76.75 E-value: 5.15e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 8 LRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLrcsNLLE--LPD---QGEIIVGGEAIEMKpnrkgqnrps 82
Cdd:NF040905 4 MRGITKTFPGVKALDDVNLSVREGEIHALCGENGAGKSTLM---KVLSgvYPHgsyEGEILFDGEVCRFK---------- 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 83 nlkqidRIRT--QLGMVF--QNFNLWSHKTVLENIIeapvhvLKRPQA--------ECVEHAEQLLEKVGLADKRHYYPA 150
Cdd:NF040905 71 ------DIRDseALGIVIihQELALIPYLSIAENIF------LGNERAkrgvidwnETNRRARELLAKVGLDESPDTLVT 138
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 497963481 151 HLSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQG 227
Cdd:NF040905 139 DIGVGKQQLVEIAKALSKDVKLLILDEPTAALNEEDSAALLDLLLELKAQGITSIIISHKLNEIRRVADSITVLRDG 215
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
4-236 |
5.90e-16 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 77.09 E-value: 5.90e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 4 PAISLRNIHKSFGS---LDVLKGISIEANQGEVISILGSSGSGKSTLLrcSNLL-ELP--DQGEIIVGGeaiemkpnrkg 77
Cdd:PLN03130 613 PAISIKNGYFSWDSkaeRPTLSNINLDVPVGSLVAIVGSTGEGKTSLI--SAMLgELPprSDASVVIRG----------- 679
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 78 qnRPSNLKQIDRIrtqlgmvfqnFNlwshKTVLENII-EAPVHVLKRPQAECV---EHAEQLLEKVGLAD--KRHyypAH 151
Cdd:PLN03130 680 --TVAYVPQVSWI----------FN----ATVRDNILfGSPFDPERYERAIDVtalQHDLDLLPGGDLTEigERG---VN 740
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 152 LSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRvmRTLADE--GMTMLVVTHEMDFAREVsNRIVFLHQGEI 229
Cdd:PLN03130 741 ISGGQKQRVSMARAVYSNSDVYIFDDPLSALDAHVGRQVFD--KCIKDElrGKTRVLVTNQLHFLSQV-DRIILVHEGMI 817
|
....*..
gi 497963481 230 EEQGTPE 236
Cdd:PLN03130 818 KEEGTYE 824
|
|
| PRK13538 |
PRK13538 |
cytochrome c biogenesis heme-transporting ATPase CcmA; |
23-209 |
6.39e-16 |
|
cytochrome c biogenesis heme-transporting ATPase CcmA;
Pssm-ID: 184125 [Multi-domain] Cd Length: 204 Bit Score: 73.68 E-value: 6.39e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 23 GISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEmkpnrkgqnrpsnlKQIDRIRTQLgmvfqnfn 102
Cdd:PRK13538 19 GLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGEPIR--------------RQRDEYHQDL-------- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 103 LW-SHK-------TVLENIIEApvHVLKRPQAEcvEHAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIARALAMEPKVML 174
Cdd:PRK13538 77 LYlGHQpgiktelTALENLRFY--QRLHGPGDD--EALWEALAQVGLAGFEDVPVRQLSAGQQRRVALARLWLTRAPLWI 152
|
170 180 190
....*....|....*....|....*....|....*
gi 497963481 175 FDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTH 209
Cdd:PRK13538 153 LDEPFTAIDKQGVARLEALLAQHAEQGGMVILTTH 187
|
|
| YddA |
COG4178 |
ABC-type uncharacterized transport system, permease and ATPase components [General function ... |
20-209 |
7.60e-16 |
|
ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];
Pssm-ID: 443337 [Multi-domain] Cd Length: 571 Bit Score: 76.38 E-value: 7.60e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 20 VLKGISIEANQGEVISILGSSGSGKSTLLRC--------SNLLELPDQGEIIVggeaiemkpnrkgqnrpsnLKQidRIR 91
Cdd:COG4178 378 LLEDLSLSLKPGERLLITGPSGSGKSTLLRAiaglwpygSGRIARPAGARVLF-------------------LPQ--RPY 436
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 92 TQLGmvfqnfnlwshkTVLEniieapvhVLKRPQAECV---EHAEQLLEKVGLAD--KRHYYPAH----LSGGQQQRAAI 162
Cdd:COG4178 437 LPLG------------TLRE--------ALLYPATAEAfsdAELREALEAVGLGHlaERLDEEADwdqvLSLGEQQRLAF 496
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 497963481 163 ARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTlADEGMTMLVVTH 209
Cdd:COG4178 497 ARLLLHKPDWLFLDEATSALDEENEAALYQLLRE-ELPGTTVISVGH 542
|
|
| ABC_RNaseL_inhibitor_domain1 |
cd03236 |
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
31-211 |
9.19e-16 |
|
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213203 [Multi-domain] Cd Length: 255 Bit Score: 74.33 E-value: 9.19e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 31 GEVISILGSSGSGKSTLLRcsnllelpdqgeIIVGgeaiEMKPNR-KGQNRPSNLKQIDRIRtqlGMVFQNFnlwshktv 109
Cdd:cd03236 26 GQVLGLVGPNGIGKSTALK------------ILAG----KLKPNLgKFDDPPDWDEILDEFR---GSELQNY-------- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 110 LENIIEAPVHVLKRPQAecVEH--------AEQLLEKVglaDKRHYYP----------------AHLSGGQQQRAAIARA 165
Cdd:cd03236 79 FTKLLEGDVKVIVKPQY--VDLipkavkgkVGELLKKK---DERGKLDelvdqlelrhvldrniDQLSGGELQRVAIAAA 153
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 497963481 166 LAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEM 211
Cdd:cd03236 154 LARDADFYFFDEPSSYLDIKQRLNAARLIRELAEDDNYVLVVEHDL 199
|
|
| PLN03211 |
PLN03211 |
ABC transporter G-25; Provisional |
20-210 |
1.66e-15 |
|
ABC transporter G-25; Provisional
Pssm-ID: 215634 [Multi-domain] Cd Length: 659 Bit Score: 75.69 E-value: 1.66e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 20 VLKGISIEANQGEVISILGSSGSGKSTLLrcsNLLELPDQGEIIVGGEAIEmkpNRKgqnrPSnlKQIDRiRTqlGMVFQ 99
Cdd:PLN03211 83 ILNGVTGMASPGEILAVLGPSGSGKSTLL---NALAGRIQGNNFTGTILAN---NRK----PT--KQILK-RT--GFVTQ 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 100 NFNLWSHKTVLENIIEapVHVLKRPQA----ECVEHAEQLLEKVGLADKRHYYPAH-----LSGGQQQRAAIARALAMEP 170
Cdd:PLN03211 148 DDILYPHLTVRETLVF--CSLLRLPKSltkqEKILVAESVISELGLTKCENTIIGNsfirgISGGERKRVSIAHEMLINP 225
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 497963481 171 KVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHE 210
Cdd:PLN03211 226 SLLILDEPTSGLDATAAYRLVLTLGSLAQKGKTIVTSMHQ 265
|
|
| znuC |
PRK09544 |
high-affinity zinc transporter ATPase; Reviewed |
3-238 |
3.47e-15 |
|
high-affinity zinc transporter ATPase; Reviewed
Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 72.84 E-value: 3.47e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 3 TPAISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIvggeaiemkpnRKGQNRPS 82
Cdd:PRK09544 2 TSLVSLENVSVSFGQRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVIK-----------RNGKLRIG 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 83 NLKQIDRIRTQLGMVFQNFNLWSHKTVLENIIEApvhvLKRPQAECVehAEQLLEKvgladkrhyypahLSGGQQQRAAI 162
Cdd:PRK09544 71 YVPQKLYLDTTLPLTVNRFLRLRPGTKKEDILPA----LKRVQAGHL--IDAPMQK-------------LSGGETQRVLL 131
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 497963481 163 ARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQgEIEEQGTPEHV 238
Cdd:PRK09544 132 ARALLNRPQLLVLDEPTQGVDVNGQVALYDLIDQLRRElDCAVLMVSHDLHLVMAKTDEVLCLNH-HICCSGTPEVV 207
|
|
| ABCC_NFT1 |
cd03369 |
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ... |
20-235 |
3.48e-15 |
|
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 72.06 E-value: 3.48e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 20 VLKGISIEANQGEVISILGSSGSGKSTL-LRCSNLLElPDQGEIIVGGEAIEMKPnrkgqnrpsnlkqIDRIRTQLGMVF 98
Cdd:cd03369 23 VLKNVSFKVKAGEKIGIVGRTGAGKSTLiLALFRFLE-AEEGKIEIDGIDISTIP-------------LEDLRSSLTIIP 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 99 QNFNLWShKTVLENIieapvhvlkRPQAECVEhaEQLLEKVGLADKrhyyPAHLSGGQQQRAAIARALAMEPKVMLFDEP 178
Cdd:cd03369 89 QDPTLFS-GTIRSNL---------DPFDEYSD--EEIYGALRVSEG----GLNLSQGQRQLLCLARALLKRPRVLVLDEA 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 497963481 179 TSALDPELVGEVLRVMRTLAdEGMTMLVVTHEM----DFArevsnRIVFLHQGEIEEQGTP 235
Cdd:cd03369 153 TASIDYATDALIQKTIREEF-TNSTILTIAHRLrtiiDYD-----KILVMDAGEVKEYDHP 207
|
|
| PRK10790 |
PRK10790 |
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein; |
1-241 |
3.72e-15 |
|
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
Pssm-ID: 182733 [Multi-domain] Cd Length: 592 Bit Score: 74.37 E-value: 3.72e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 1 MTTPAISLRNIhkSFGSLD---VLKGISIEANQGEVISILGSSGSGKSTLlrcSNLLE---LPDQGEIIVGGeaiemkpn 74
Cdd:PRK10790 336 LQSGRIDIDNV--SFAYRDdnlVLQNINLSVPSRGFVALVGHTGSGKSTL---ASLLMgyyPLTEGEIRLDG-------- 402
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 75 rkgqnRPSNLKQIDRIRTQLGMVFQNFNLWShKTVLENIieapvhVLKRPQAEcvEHAEQLLEKVGLADKRHYYPA---- 150
Cdd:PRK10790 403 -----RPLSSLSHSVLRQGVAMVQQDPVVLA-DTFLANV------TLGRDISE--EQVWQALETVQLAELARSLPDglyt 468
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 151 -------HLSGGQQQRAAIARALAMEPKVMLFDEPTSALDP---ELVGEVLRVMRtladEGMTMLVVTHEMDFAREVSNr 220
Cdd:PRK10790 469 plgeqgnNLSVGQKQLLALARVLVQTPQILILDEATANIDSgteQAIQQALAAVR----EHTTLVVIAHRLSTIVEADT- 543
|
250 260
....*....|....*....|.
gi 497963481 221 IVFLHQGEIEEQGTPEHVFTA 241
Cdd:PRK10790 544 ILVLHRGQAVEQGTHQQLLAA 564
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
10-223 |
4.38e-15 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 74.07 E-value: 4.38e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 10 NIHKSFG--SLDVLKGisiEANQGEVISILGSSGSGKSTLLRcsnLL---ELPDQGEIiVGGEAIEMKPnrkgqnrpsnl 84
Cdd:PRK13409 345 DLTKKLGdfSLEVEGG---EIYEGEVIGIVGPNGIGKTTFAK---LLagvLKPDEGEV-DPELKISYKP----------- 406
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 85 kQidRIRTQLGMVFQNFnLWSHKTVL-ENIIEapVHVLKRPQAEcvehaeQLLEKvgladkrhyYPAHLSGGQQQRAAIA 163
Cdd:PRK13409 407 -Q--YIKPDYDGTVEDL-LRSITDDLgSSYYK--SEIIKPLQLE------RLLDK---------NVKDLSGGELQRVAIA 465
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 497963481 164 RALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNR-IVF 223
Cdd:PRK13409 466 ACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRRIAEErEATALVVDHDIYMIDYISDRlMVF 527
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
24-241 |
1.42e-14 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 72.64 E-value: 1.42e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 24 ISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEMKPNRKGQNRPSNLKQIDRirTQLGMVfqnfnl 103
Cdd:PRK11288 272 ISFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLDGKPIDIRSPRDAIRAGIMLCPEDR--KAEGII------ 343
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 104 wSHKTVLENI-IEAPVHVLK-----RPQAEcVEHAEQLLEKvgLADK---RHYYPAHLSGGQQQRAAIARALAMEPKVML 174
Cdd:PRK11288 344 -PVHSVADNInISARRHHLRagcliNNRWE-AENADRFIRS--LNIKtpsREQLIMNLSGGNQQKAILGRWLSEDMKVIL 419
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 497963481 175 FDEPTSALDpelVG---EVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEI-----EEQGTPEHVFTA 241
Cdd:PRK11288 420 LDEPTRGID---VGakhEIYNVIYELAAQGVAVLFVSSDLPEVLGVADRIVVMREGRIagelaREQATERQALSL 491
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
150-241 |
1.45e-14 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 72.65 E-value: 1.45e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 150 AHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDpelVG---EVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQ 226
Cdd:PRK13549 404 ARLSGGNQQKAVLAKCLLLNPKILILDEPTRGID---VGakyEIYKLINQLVQQGVAIIVISSELPEVLGLSDRVLVMHE 480
|
90 100
....*....|....*....|
gi 497963481 227 GEIE-----EQGTPEHVFTA 241
Cdd:PRK13549 481 GKLKgdlinHNLTQEQVMEA 500
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
30-211 |
4.75e-14 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 71.35 E-value: 4.75e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 30 QGEVISILGSSGSGKSTLLRcsnllelpdqgeiIVGGEaieMKPNR-KGQNRPSNLKQIDRIRtqlGMVFQNFnlwshkt 108
Cdd:COG1245 98 KGKVTGILGPNGIGKSTALK-------------ILSGE---LKPNLgDYDEEPSWDEVLKRFR---GTELQDY------- 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 109 vLENIIEAPVHVLKRPQAecVEHA--------EQLLEKV---GLADK-------RHYYP---AHLSGGQQQRAAIARALA 167
Cdd:COG1245 152 -FKKLANGEIKVAHKPQY--VDLIpkvfkgtvRELLEKVderGKLDElaeklglENILDrdiSELSGGELQRVAIAAALL 228
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 497963481 168 MEPKVMLFDEPTSALDpelVGE---VLRVMRTLADEGMTMLVVTHEM 211
Cdd:COG1245 229 RDADFYFFDEPSSYLD---IYQrlnVARLIRELAEEGKYVLVVEHDL 272
|
|
| 40850658_otr |
NF000106 |
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit; |
5-240 |
5.21e-14 |
|
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 70.53 E-value: 5.21e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 5 AISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLElPDQGEiivggeaiemKPNRKGQ---NRP 81
Cdd:NF000106 13 AVEVRGLVKHFGEVKAVDGVDLDVREGTVLGVLGP*GAA**RGALPAHV*G-PDAGR----------RPWRF*TwcaNRR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 82 SNLKQIDRIRTQLGMVFQNFNLWSHKTVLENIIEapvhvLKRPQAECveHAEQLLEKVGLADKRHYYPAHLSGGQQQRAA 161
Cdd:NF000106 82 ALRRTIG*HRPVR*GRRESFSGRENLYMIGR*LD-----LSRKDARA--RADELLERFSLTEAAGRAAAKYSGGMRRRLD 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 497963481 162 IARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVFT 240
Cdd:NF000106 155 LAASMIGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMVRDGATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDELKT 233
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
21-236 |
7.07e-14 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 70.42 E-value: 7.07e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 21 LKGISIEANQGEVISILGSSGSGKSTLLRcsnLL--ELP-DQGEIIVGGEAIEmkpNRKGQNRPSN-LKQI--DRIRTQL 94
Cdd:PRK10762 268 VNDVSFTLRKGEILGVSGLMGAGRTELMK---VLygALPrTSGYVTLDGHEVV---TRSPQDGLANgIVYIseDRKRDGL 341
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 95 --GM-VFQNFNLwshkTVLENIIEAPVHVLKRPQAECVEHAEQLL--------EKVGLadkrhyypahLSGGQQQRAAIA 163
Cdd:PRK10762 342 vlGMsVKENMSL----TALRYFSRAGGSLKHADEQQAVSDFIRLFniktpsmeQAIGL----------LSGGNQQKVAIA 407
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 164 RALAMEPKVMLFDEPTSALDpelVG---EVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIE-----EQGTP 235
Cdd:PRK10762 408 RGLMTRPKVLILDEPTRGVD---VGakkEIYQLINQFKAEGLSIILVSSEMPEVLGMSDRILVMHEGRISgeftrEQATQ 484
|
.
gi 497963481 236 E 236
Cdd:PRK10762 485 E 485
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
1-223 |
7.73e-14 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 70.58 E-value: 7.73e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 1 MTTPAISLRNIHKSFG--SLDVLKGisiEANQGEVISILGSSGSGKSTLLRcsnLL---ELPDQGEIIvGGEAIEMKPnr 75
Cdd:COG1245 337 EEETLVEYPDLTKSYGgfSLEVEGG---EIREGEVLGIVGPNGIGKTTFAK---ILagvLKPDEGEVD-EDLKISYKP-- 407
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 76 kgqnrpsnlkQidRIRTQLGMVFQnfnlwshkTVLENIIEAPV-------HVLKRPQAEcvehaeQLLEKvgladkrhyY 148
Cdd:COG1245 408 ----------Q--YISPDYDGTVE--------EFLRSANTDDFgssyyktEIIKPLGLE------KLLDK---------N 452
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 497963481 149 PAHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRI-VF 223
Cdd:COG1245 453 VKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRRFAENrGKTAMVVDHDIYLIDYISDRLmVF 529
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
6-229 |
1.25e-13 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 69.98 E-value: 1.25e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLDVLKG--ISIEANqgEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAI----EMKPNRKGQ- 78
Cdd:PRK11147 4 ISIHGAWLSFSDAPLLDNaeLHIEDN--ERVCLVGRNGAGKSTLMKILNGEVLLDDGRIIYEQDLIvarlQQDPPRNVEg 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 79 ----------------------------NRPS--NLKQIDRIRTQLgmvfQNFNLWShktvLENIIEapvhvlkrpqaec 128
Cdd:PRK11147 82 tvydfvaegieeqaeylkryhdishlveTDPSekNLNELAKLQEQL----DHHNLWQ----LENRIN------------- 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 129 vehaeQLLEKVGL-ADKRHyypAHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVgEVLRVMrtLADEGMTMLVV 207
Cdd:PRK11147 141 -----EVLAQLGLdPDAAL---SSLSGGWLRKAALGRALVSNPDVLLLDEPTNHLDIETI-EWLEGF--LKTFQGSIIFI 209
|
250 260
....*....|....*....|..
gi 497963481 208 THEMDFAREVSNRIVFLHQGEI 229
Cdd:PRK11147 210 SHDRSFIRNMATRIVDLDRGKL 231
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
3-242 |
1.55e-13 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 70.00 E-value: 1.55e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 3 TPAISLRNIHKSFGSL---DVLKGISIEANQGEVISILGSSGSGKSTLLRcSNLLELP--DQGEIIVGGeAIEMKPnrkg 77
Cdd:PLN03232 612 APAISIKNGYFSWDSKtskPTLSDINLEIPVGSLVAIVGGTGEGKTSLIS-AMLGELShaETSSVVIRG-SVAYVP---- 685
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 78 qnrpsnlkqidrirtQLGMVFqnfnlwsHKTVLENIIEA----PVHVLKRPQAECVEHAEQLLEKVGLAD--KRHyypAH 151
Cdd:PLN03232 686 ---------------QVSWIF-------NATVRENILFGsdfeSERYWRAIDVTALQHDLDLLPGRDLTEigERG---VN 740
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 152 LSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVsNRIVFLHQGEIEE 231
Cdd:PLN03232 741 ISGGQKQRVSMARAVYSNSDIYIFDDPLSALDAHVAHQVFDSCMKDELKGKTRVLVTNQLHFLPLM-DRIILVSEGMIKE 819
|
250
....*....|.
gi 497963481 232 QGTPEHVFTAS 242
Cdd:PLN03232 820 EGTFAELSKSG 830
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
24-230 |
1.97e-13 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 69.47 E-value: 1.97e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 24 ISIEANQGEVISILGSSGSGKSTLLRC-SNLLELPDQGEIIVGGEAIEMKPNRKGQNRPSNLKQIDRIRTqlGMVfqnfn 102
Cdd:TIGR02633 279 VSFSLRRGEILGVAGLVGAGRTELVQAlFGAYPGKFEGNVFINGKPVDIRNPAQAIRAGIAMVPEDRKRH--GIV----- 351
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 103 lwSHKTVLENIIEApvhVLKRPQAECVEHAEQLLEKVGLADKR-HYYPAH-------LSGGQQQRAAIARALAMEPKVML 174
Cdd:TIGR02633 352 --PILGVGKNITLS---VLKSFCFKMRIDAAAELQIIGSAIQRlKVKTASpflpigrLSGGNQQKAVLAKMLLTNPRVLI 426
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 497963481 175 FDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIE 230
Cdd:TIGR02633 427 LDEPTRGVDVGAKYEIYKLINQLAQEGVAIIVVSSELAEVLGLSDRVLVIGEGKLK 482
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
20-228 |
3.51e-13 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 68.42 E-value: 3.51e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 20 VLKGISIEANQGEVISILGSSGSGKSTLLRcsnllelpdqgeIIVG------GEAIEMkPNRKgqnrpsnlkqidrirtq 93
Cdd:TIGR03719 20 ILKDISLSFFPGAKIGVLGLNGAGKSTLLR------------IMAGvdkdfnGEARPQ-PGIK----------------- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 94 LGMVFQNFNLWSHKTVLENIIEA---PVHVLKR----------PQAEcvehAEQLLEKVG-LADKRHYYPAH-------- 151
Cdd:TIGR03719 70 VGYLPQEPQLDPTKTVRENVEEGvaeIKDALDRfneisakyaePDAD----FDKLAAEQAeLQEIIDAADAWdldsqlei 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 152 ----------------LSGGQQQRAAIARALAMEPKVMLFDEPTSALDPElvgEVLRVMRTLADEGMTMLVVTHEMDFAR 215
Cdd:TIGR03719 146 amdalrcppwdadvtkLSGGERRRVALCRLLLSKPDMLLLDEPTNHLDAE---SVAWLERHLQEYPGTVVAVTHDRYFLD 222
|
250
....*....|...
gi 497963481 216 EVSNRIVFLHQGE 228
Cdd:TIGR03719 223 NVAGWILELDRGR 235
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
20-210 |
4.35e-13 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 68.60 E-value: 4.35e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 20 VLKGISIEANQGEVISILGSSGSGKSTLLRCsnLLELPDQGeIIVGGEAIEmkpnrKGQNRPSNLKQIdrirtqLGMVFQ 99
Cdd:TIGR00956 778 ILNNVDGWVKPGTLTALMGASGAGKTTLLNV--LAERVTTG-VITGGDRLV-----NGRPLDSSFQRS------IGYVQQ 843
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 100 NFNLWSHKTVLENIIEA-----PVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPAH-LSGGQQQRAAIARALAMEPKVM 173
Cdd:TIGR00956 844 QDLHLPTSTVRESLRFSaylrqPKSVSKSEKMEYVEEVIKLLEMESYADAVVGVPGEgLNVEQRKRLTIGVELVAKPKLL 923
|
170 180 190
....*....|....*....|....*....|....*...
gi 497963481 174 LF-DEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHE 210
Cdd:TIGR00956 924 LFlDEPTSGLDSQTAWSICKLMRKLADHGQAILCTIHQ 961
|
|
| hmuV |
PRK13547 |
heme ABC transporter ATP-binding protein; |
20-246 |
4.67e-13 |
|
heme ABC transporter ATP-binding protein;
Pssm-ID: 184132 [Multi-domain] Cd Length: 272 Bit Score: 67.16 E-value: 4.67e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 20 VLKGISIEANQGEVISILGSSGSGKSTLLRcSNLLELPD----QGEIIVGGEAIEMKPnrkgqnrpsnLKQID-----RI 90
Cdd:PRK13547 16 ILRDLSLRIEPGRVTALLGRNGAGKSTLLK-ALAGDLTGggapRGARVTGDVTLNGEP----------LAAIDaprlaRL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 91 RTQLGMVFQNFNLWShktvLENIIEAPVHVLKRPQAECVEH----AEQLLEKVGLADKRHYYPAHLSGGQQQRAAIARAL 166
Cdd:PRK13547 85 RAVLPQAAQPAFAFS----AREIVLLGRYPHARRAGALTHRdgeiAWQALALAGATALVGRDVTTLSGGELARVQFARVL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 167 AM---------EPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPE 236
Cdd:PRK13547 161 AQlwpphdaaqPPRYLLLDEPTAALDLAHQHRLLDTVRRLARDwNLGVLAIVHDPNLAARHADRIAMLADGAIVAHGAPA 240
|
250
....*....|
gi 497963481 237 HVFTASQSAR 246
Cdd:PRK13547 241 DVLTPAHIAR 250
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
30-211 |
7.57e-13 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 67.53 E-value: 7.57e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 30 QGEVISILGSSGSGKSTLLRcsnllelpdqgeiIVGGEaieMKPNRKGQNRPSNLKQ-IDRIRtqlGMVFQNFnlwshkt 108
Cdd:PRK13409 98 EGKVTGILGPNGIGKTTAVK-------------ILSGE---LIPNLGDYEEEPSWDEvLKRFR---GTELQNY------- 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 109 vLENIIEAPVHVLKRPQAecVEHA--------EQLLEKV---GLADK------------RHYypAHLSGGQQQRAAIARA 165
Cdd:PRK13409 152 -FKKLYNGEIKVVHKPQY--VDLIpkvfkgkvRELLKKVderGKLDEvverlglenildRDI--SELSGGELQRVAIAAA 226
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 497963481 166 LAMEPKVMLFDEPTSALDpelVGEVLRVMRTLAD--EGMTMLVVTHEM 211
Cdd:PRK13409 227 LLRDADFYFFDEPTSYLD---IRQRLNVARLIRElaEGKYVLVVEHDL 271
|
|
| ABCC_SUR1_N |
cd03290 |
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ... |
14-213 |
1.14e-12 |
|
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213257 [Multi-domain] Cd Length: 218 Bit Score: 65.04 E-value: 1.14e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 14 SFGS-LDVLKGISIEANQGEVISILGSSGSGKSTLLrcsnlleLPDQGEIivggEAIEMKPNRKGQNRPSNLKQIDRIRT 92
Cdd:cd03290 9 SWGSgLATLSNINIRIPTGQLTMIVGQVGCGKSSLL-------LAILGEM----QTLEGKVHWSNKNESEPSFEATRSRN 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 93 QLGMVFQNFNLWS-HKTVLENII-EAPVHVLK----------RPQAECVEHAEQL-LEKVGLadkrhyypaHLSGGQQQR 159
Cdd:cd03290 78 RYSVAYAAQKPWLlNATVEENITfGSPFNKQRykavtdacslQPDIDLLPFGDQTeIGERGI---------NLSGGQRQR 148
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 497963481 160 AAIARALAMEPKVMLFDEPTSALDPELVGEVLR--VMRTLADEGMTMLVVTHEMDF 213
Cdd:cd03290 149 ICVARALYQNTNIVFLDDPFSALDIHLSDHLMQegILKFLQDDKRTLVLVTHKLQY 204
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
20-241 |
1.18e-12 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 67.28 E-value: 1.18e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 20 VLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGeaiemkpnrkgqnrpSNLKQI--DRIRTQLGMV 97
Cdd:TIGR00957 1301 VLRHINVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDG---------------LNIAKIglHDLRFKITII 1365
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 98 FQN--------------FNLWSHKTVLENIIEAPVH--VLKRPQA---ECVEHAEqllekvgladkrhyypaHLSGGQQQ 158
Cdd:TIGR00957 1366 PQDpvlfsgslrmnldpFSQYSDEEVWWALELAHLKtfVSALPDKldhECAEGGE-----------------NLSVGQRQ 1428
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 159 RAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEgMTMLVVTHE----MDFarevsNRIVFLHQGEIEEQGT 234
Cdd:TIGR00957 1429 LVCLARALLRKTKILVLDEATAAVDLETDNLIQSTIRTQFED-CTVLTIAHRlntiMDY-----TRVIVLDKGEVAEFGA 1502
|
....*..
gi 497963481 235 PEHVFTA 241
Cdd:TIGR00957 1503 PSNLLQQ 1509
|
|
| PvdE |
COG4615 |
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ... |
6-231 |
2.63e-12 |
|
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];
Pssm-ID: 443659 [Multi-domain] Cd Length: 547 Bit Score: 65.97 E-value: 2.63e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLD-----VLKGISIEANQGEVISILGSSGSGKSTLLRcsNLLEL--PDQGEIIVGGEAIEmkpnrkGQ 78
Cdd:COG4615 328 LELRGVTYRYPGEDgdegfTLGPIDLTIRRGELVFIVGGNGSGKSTLAK--LLTGLyrPESGEILLDGQPVT------AD 399
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 79 NRpsnlkqiDRIRTQLGMVFQNFNLWShktvleniieapvHVLKRPQAECVEHAEQLLEKVGLADK-----RHYYPAHLS 153
Cdd:COG4615 400 NR-------EAYRQLFSAVFSDFHLFD-------------RLLGLDGEADPARARELLERLELDHKvsvedGRFSTTDLS 459
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 154 GGQQQRAAIARALAMEPKVMLFDEPTSALDP--------ELVGEvlrvmrtLADEGMTMLVVTHemD---FarEVSNRIV 222
Cdd:COG4615 460 QGQRKRLALLVALLEDRPILVFDEWAADQDPefrrvfytELLPE-------LKARGKTVIAISH--DdryF--DLADRVL 528
|
....*....
gi 497963481 223 FLHQGEIEE 231
Cdd:COG4615 529 KMDYGKLVE 537
|
|
| ABCD_peroxisomal_ALDP |
cd03223 |
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ... |
152-209 |
3.79e-12 |
|
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).
Pssm-ID: 213190 [Multi-domain] Cd Length: 166 Bit Score: 62.56 E-value: 3.79e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 497963481 152 LSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGevlRVMRTLADEGMTMLVVTH 209
Cdd:cd03223 92 LSGGEQQRLAFARLLLHKPKFVFLDEATSALDEESED---RLYQLLKELGITVISVGH 146
|
|
| PRK10522 |
PRK10522 |
multidrug transporter membrane component/ATP-binding component; Provisional |
6-231 |
4.65e-12 |
|
multidrug transporter membrane component/ATP-binding component; Provisional
Pssm-ID: 236707 [Multi-domain] Cd Length: 547 Bit Score: 65.38 E-value: 4.65e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFG--SLDVlKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEMkpnrkgqnrpsn 83
Cdd:PRK10522 323 LELRNVTFAYQdnGFSV-GPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVTA------------ 389
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 84 lKQIDRIRTQLGMVFQNFNLWSHktvleniieapvhvLKRPQAECVEHA--EQLLEKVGLADKRHY-----YPAHLSGGQ 156
Cdd:PRK10522 390 -EQPEDYRKLFSAVFTDFHLFDQ--------------LLGPEGKPANPAlvEKWLERLKMAHKLELedgriSNLKLSKGQ 454
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 497963481 157 QQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHEmDFAREVSNRIVFLHQGEIEE 231
Cdd:PRK10522 455 KKRLALLLALAEERDILLLDEWAADQDPHFRREFYQVLLPLLQEmGKTIFAISHD-DHYFIHADRLLEMRNGQLSE 529
|
|
| ycf16 |
CHL00131 |
sulfate ABC transporter protein; Validated |
1-209 |
4.83e-12 |
|
sulfate ABC transporter protein; Validated
Pssm-ID: 214372 [Multi-domain] Cd Length: 252 Bit Score: 63.89 E-value: 4.83e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 1 MTTPAISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLR------CSNLLElpdqGEIIVGGEAI-EMKP 73
Cdd:CHL00131 3 KNKPILEIKNLHASVNENEILKGLNLSINKGEIHAIMGPNGSGKSTLSKviaghpAYKILE----GDILFKGESIlDLEP 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 74 NrkgqnrpsnlkqidrIRTQLG--MVFQN---FNLWSHKTVLENIIEAPVHVLKRPQAECVEHAEQLLEKVGLAD-KRHY 147
Cdd:CHL00131 79 E---------------ERAHLGifLAFQYpieIPGVSNADFLRLAYNSKRKFQGLPELDPLEFLEIINEKLKLVGmDPSF 143
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 497963481 148 YPAHL----SGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTH 209
Cdd:CHL00131 144 LSRNVnegfSGGEKKRNEILQMALLDSELAILDETDSGLDIDALKIIAEGINKLMTSENSIILITH 209
|
|
| ABC_UvrA_II |
cd03271 |
ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair ... |
21-235 |
5.37e-12 |
|
ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213238 [Multi-domain] Cd Length: 261 Bit Score: 63.79 E-value: 5.37e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 21 LKGISIEANQGEVISILGSSGSGKSTLL------RCSNLLEL----PDQGEIIVGGEAIE--MKPNRK--GQNRPSN--- 83
Cdd:cd03271 11 LKNIDVDIPLGVLTCVTGVSGSGKSSLIndtlypALARRLHLkkeqPGNHDRIEGLEHIDkvIVIDQSpiGRTPRSNpat 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 84 -LKQIDRIRTqlgmVF------QNFN------LWSHKT---VLENIIEAPVHVLKR-PQaecVEHAEQLLEKVGLADKRH 146
Cdd:cd03271 91 yTGVFDEIRE----LFcevckgKRYNretlevRYKGKSiadVLDMTVEEALEFFENiPK---IARKLQTLCDVGLGYIKL 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 147 YYPAH-LSGGQQQRAAIARALAME---PKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAReVSNRIV 222
Cdd:cd03271 164 GQPATtLSGGEAQRIKLAKELSKRstgKTLYILDEPTTGLHFHDVKKLLEVLQRLVDKGNTVVVIEHNLDVIK-CADWII 242
|
250
....*....|....*....
gi 497963481 223 FL------HQGEIEEQGTP 235
Cdd:cd03271 243 DLgpeggdGGGQVVASGTP 261
|
|
| PRK13543 |
PRK13543 |
heme ABC exporter ATP-binding protein CcmA; |
9-224 |
3.45e-11 |
|
heme ABC exporter ATP-binding protein CcmA;
Pssm-ID: 184129 [Multi-domain] Cd Length: 214 Bit Score: 61.02 E-value: 3.45e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 9 RNIHKSFGSLDvlkgisIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIivggeAIEMKPNRKGqnrpsnlkqiD 88
Cdd:PRK13543 21 RNEEPVFGPLD------FHVDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQI-----QIDGKTATRG----------D 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 89 RIR-----TQLGMVFQNFnlwshkTVLENIieapvHVLKRPQAEcveHAEQL----LEKVGLADKRHYYPAHLSGGQQQR 159
Cdd:PRK13543 80 RSRfmaylGHLPGLKADL------STLENL-----HFLCGLHGR---RAKQMpgsaLAIVGLAGYEDTLVRQLSAGQKKR 145
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 497963481 160 AAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFL 224
Cdd:PRK13543 146 LALARLWLSPAPLWLLDEPYANLDLEGITLVNRMISAHLRGGGAALVTTHGAYAAPPVRTRMLTL 210
|
|
| ABCG_PDR_domain1 |
cd03233 |
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ... |
6-206 |
3.47e-11 |
|
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213200 [Multi-domain] Cd Length: 202 Bit Score: 60.74 E-value: 3.47e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIH----KSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRC-SNLLELPDQ--GEIIVGGeaIEMKPNRKgq 78
Cdd:cd03233 4 LSWRNISfttgKGRSKIPILKDFSGVVKPGEMVLVLGRPGSGCSTLLKAlANRTEGNVSveGDIHYNG--IPYKEFAE-- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 79 nrpsnlkqidRIRTQLGMVFQNFNLWSHKTVleniieapvhvlkrpqaecvehaEQLLEKVGLAdKRHYYPAHLSGGQQQ 158
Cdd:cd03233 80 ----------KYPGEIIYVSEEDVHFPTLTV-----------------------RETLDFALRC-KGNEFVRGISGGERK 125
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 497963481 159 RAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLV 206
Cdd:cd03233 126 RVSIAEALVSRASVLCWDNSTRGLDSSTALEILKCIRTMADVlKTTTFV 174
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
3-229 |
4.00e-11 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 62.34 E-value: 4.00e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 3 TPAISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRC---------SNLLELpdqgeiivggeaiemkp 73
Cdd:PRK10938 258 EPRIVLNNGVVSYNDRPILHNLSWQVNPGEHWQIVGPNGAGKSTLLSLitgdhpqgySNDLTL----------------- 320
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 74 nrKGQNRPSNlKQIDRIRTQLGMVFQNFNL-WSHKTVLENIIEAPVH--------VLKRPQAEcvehAEQLLEKVGLADK 144
Cdd:PRK10938 321 --FGRRRGSG-ETIWDIKKHIGYVSSSLHLdYRVSTSVRNVILSGFFdsigiyqaVSDRQQKL----AQQWLDILGIDKR 393
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 145 RHYYPAH-LSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTML--VVTHEMDFAREVSNRI 221
Cdd:PRK10938 394 TADAPFHsLSWGQQRLALIVRALVKHPTLLILDEPLQGLDPLNRQLVRRFVDVLISEGETQLlfVSHHAEDAPACITHRL 473
|
....*...
gi 497963481 222 VFLHQGEI 229
Cdd:PRK10938 474 EFVPDGDI 481
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
148-251 |
4.89e-11 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 62.74 E-value: 4.89e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 148 YPAHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDP---ELVGEVLRVMRTLADEgmTMLVVTHEMDFAREvSNRIVFL 224
Cdd:PTZ00265 1355 YGKSLSGGQKQRIAIARALLREPKILLLDEATSSLDSnseKLIEKTIVDIKDKADK--TIITIAHRIASIKR-SDKIVVF 1431
|
90 100 110
....*....|....*....|....*....|..
gi 497963481 225 HQGE-----IEEQGTPEHVFTAsQSARFRQFI 251
Cdd:PTZ00265 1432 NNPDrtgsfVQAHGTHEELLSV-QDGVYKKYV 1462
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
6-228 |
6.82e-11 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 61.97 E-value: 6.82e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGS---LDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGG---------------- 66
Cdd:PTZ00265 383 IQFKNVRFHYDTrkdVEIYKDLNFTLTEGKTYAFVGESGCGKSTILKLIERLYDPTEGDIIINDshnlkdinlkwwrski 462
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 67 ----------------------------EAIEMKPNRKGQNRPSNLKQIDRIRTQLGmvfQNFNLWSHKTVLENIIEApv 118
Cdd:PTZ00265 463 gvvsqdpllfsnsiknnikyslyslkdlEALSNYYNEDGNDSQENKNKRNSCRAKCA---GDLNDMSNTTDSNELIEM-- 537
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 119 hvlkRPQAECVEHAE--QLLEKVGLADKRHYYP-----------AHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDPE 185
Cdd:PTZ00265 538 ----RKNYQTIKDSEvvDVSKKVLIHDFVSALPdkyetlvgsnaSKLSGGQKQRISIARAIIRNPKILILDEATSSLDNK 613
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 497963481 186 LVGEVLRVMRTL-ADEGMTMLVVTHEMDFAReVSNRIVFLHQGE 228
Cdd:PTZ00265 614 SEYLVQKTINNLkGNENRITIIIAHRLSTIR-YANTIFVLSNRE 656
|
|
| sufC |
PRK09580 |
cysteine desulfurase ATPase component; Reviewed |
6-233 |
1.42e-10 |
|
cysteine desulfurase ATPase component; Reviewed
Pssm-ID: 181965 [Multi-domain] Cd Length: 248 Bit Score: 59.80 E-value: 1.42e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLlrcSNLLELPDQGEiIVGGEAIemkpnRKGQNRpSNLK 85
Cdd:PRK09580 2 LSIKDLHVSVEDKAILRGLNLEVRPGEVHAIMGPNGSGKSTL---SATLAGREDYE-VTGGTVE-----FKGKDL-LELS 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 86 QIDRIRTQLGMVFQ---NFNLWSHKTVLENIIEAPVHVLKRPQAECVEHAEQLLEKVGLADkrhyYPAHL---------S 153
Cdd:PRK09580 72 PEDRAGEGIFMAFQypvEIPGVSNQFFLQTALNAVRSYRGQEPLDRFDFQDLMEEKIALLK----MPEDLltrsvnvgfS 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 154 GGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHE---MDFARevSNRIVFLHQGEIE 230
Cdd:PRK09580 148 GGEKKRNDILQMAVLEPELCILDESDSGLDIDALKIVADGVNSLRDGKRSFIIVTHYqriLDYIK--PDYVHVLYQGRIV 225
|
...
gi 497963481 231 EQG 233
Cdd:PRK09580 226 KSG 228
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
21-234 |
1.81e-10 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 60.73 E-value: 1.81e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 21 LKGISIEANQGEVISILGSSGSGKSTLLrcSNLLelpdqGEIivggEAIEMKPNRKGQnrpsnlkqidrirtqLGMVFQN 100
Cdd:TIGR00957 654 LNGITFSIPEGALVAVVGQVGCGKSSLL--SALL-----AEM----DKVEGHVHMKGS---------------VAYVPQQ 707
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 101 fnLW-SHKTVLENIIEApvHVLKRPQAECVEHAEQLL---------EKVGLADKrhyyPAHLSGGQQQRAAIARALAMEP 170
Cdd:TIGR00957 708 --AWiQNDSLRENILFG--KALNEKYYQQVLEACALLpdleilpsgDRTEIGEK----GVNLSGGQKQRVSLARAVYSNA 779
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 497963481 171 KVMLFDEPTSALDPELVGEVLRvmRTLADEGM----TMLVVTHEMDFAREVsNRIVFLHQGEIEEQGT 234
Cdd:TIGR00957 780 DIYLFDDPLSAVDAHVGKHIFE--HVIGPEGVlknkTRILVTHGISYLPQV-DVIIVMSGGKISEMGS 844
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
152-229 |
2.30e-10 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 60.06 E-value: 2.30e-10
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 497963481 152 LSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEI 229
Cdd:PRK15439 404 LSGGNQQKVLIAKCLEASPQLLIVDEPTRGVDVSARNDIYQLIRSIAAQNVAVLFISSDLEEIEQMADRVLVMHQGEI 481
|
|
| ABC_UvrA |
cd03238 |
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ... |
134-233 |
3.98e-10 |
|
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213205 [Multi-domain] Cd Length: 176 Bit Score: 57.33 E-value: 3.98e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 134 QLLEKVGLAdkrhYYP-----AHLSGGQQQRAAIARALAMEPK--VMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLV 206
Cdd:cd03238 69 QFLIDVGLG----YLTlgqklSTLSGGELQRVKLASELFSEPPgtLFILDEPSTGLHQQDINQLLEVIKGLIDLGNTVIL 144
|
90 100 110
....*....|....*....|....*....|...
gi 497963481 207 VTHEMDFAREvSNRIVFL------HQGEIEEQG 233
Cdd:cd03238 145 IEHNLDVLSS-ADWIIDFgpgsgkSGGKVVFSG 176
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
20-248 |
5.73e-10 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 59.22 E-value: 5.73e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 20 VLKGISIEANQGEVISILGSSGSGKSTLLRC-SNLLELpDQGEIIVGGEAIemkpnrkGQNRPSNLKQIDRIRTQLGMVF 98
Cdd:PLN03232 1251 VLHGLSFFVSPSEKVGVVGRTGAGKSSMLNAlFRIVEL-EKGRIMIDDCDV-------AKFGLTDLRRVLSIIPQSPVLF 1322
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 99 QN---FN-----------LWS--HKTVLENIIEAPVHVLkrpQAECVEHAEqllekvgladkrhyypaHLSGGQQQRAAI 162
Cdd:PLN03232 1323 SGtvrFNidpfsehndadLWEalERAHIKDVIDRNPFGL---DAEVSEGGE-----------------NFSVGQRQLLSL 1382
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 163 ARALAMEPKVMLFDEPTSALDpelVGEVLRVMRTLADE--GMTMLVVTHEMDFAREVsNRIVFLHQGEIEEQGTPEHVFT 240
Cdd:PLN03232 1383 ARALLRRSKILVLDEATASVD---VRTDSLIQRTIREEfkSCTMLVIAHRLNTIIDC-DKILVLSSGQVLEYDSPQELLS 1458
|
....*...
gi 497963481 241 ASQSARFR 248
Cdd:PLN03232 1459 RDTSAFFR 1466
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
20-245 |
2.16e-09 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 57.44 E-value: 2.16e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 20 VLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIemkpnrkgqnrpSNLKQIDrIRTQLGMVFQ 99
Cdd:PLN03130 1254 VLHGLSFEISPSEKVGIVGRTGAGKSSMLNALFRIVELERGRILIDGCDI------------SKFGLMD-LRKVLGIIPQ 1320
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 100 NFNLWShKTVLENIieAPVHvlkrpqaecvEHAE----QLLEKVGLADKRHYYPAHL-----------SGGQQQRAAIAR 164
Cdd:PLN03130 1321 APVLFS-GTVRFNL--DPFN----------EHNDadlwESLERAHLKDVIRRNSLGLdaevseagenfSVGQRQLLSLAR 1387
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 165 ALAMEPKVMLFDEPTSALDpelVGEVLRVMRTLADE--GMTMLVVTHEMDFAREvSNRIVFLHQGEIEEQGTPEHVFTAS 242
Cdd:PLN03130 1388 ALLRRSKILVLDEATAAVD---VRTDALIQKTIREEfkSCTMLIIAHRLNTIID-CDRILVLDAGRVVEFDTPENLLSNE 1463
|
...
gi 497963481 243 QSA 245
Cdd:PLN03130 1464 GSA 1466
|
|
| uvra |
TIGR00630 |
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ... |
134-238 |
2.95e-09 |
|
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273184 [Multi-domain] Cd Length: 925 Bit Score: 56.95 E-value: 2.95e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 134 QLLEKVGLADKRHYYPAH-LSGGQQQRAAIARAL---AMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTH 209
Cdd:TIGR00630 811 QTLCDVGLGYIRLGQPATtLSGGEAQRIKLAKELskrSTGRTLYILDEPTTGLHFDDIKKLLEVLQRLVDKGNTVVVIEH 890
|
90 100 110
....*....|....*....|....*....|....*
gi 497963481 210 EMDFAReVSNRIVFL------HQGEIEEQGTPEHV 238
Cdd:TIGR00630 891 NLDVIK-TADYIIDLgpeggdGGGTVVASGTPEEV 924
|
|
| tagH |
PRK13545 |
teichoic acids export protein ATP-binding subunit; Provisional |
21-251 |
4.43e-09 |
|
teichoic acids export protein ATP-binding subunit; Provisional
Pssm-ID: 184130 [Multi-domain] Cd Length: 549 Bit Score: 56.44 E-value: 4.43e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 21 LKGISIEANQGEVISILGSSGSGKSTLlrcSNLL---ELPDQGEIIVGGEAIEMKPNRKGQNRPSNLKQIDRIRTQLGMV 97
Cdd:PRK13545 40 LNNISFEVPEGEIVGIIGLNGSGKSTL---SNLIagvTMPNKGTVDIKGSAALIAISSGLNGQLTGIENIELKGLMMGLT 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 98 fqnfnlwshKTVLENIIeapvhvlkrpqAECVEHAEqllekVGladKRHYYPAH-LSGGQQQRAAIARALAMEPKVMLFD 176
Cdd:PRK13545 117 ---------KEKIKEII-----------PEIIEFAD-----IG---KFIYQPVKtYSSGMKSRLGFAISVHINPDILVID 168
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 497963481 177 EPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHVFTasqsaRFRQFI 251
Cdd:PRK13545 169 EALSVGDQTFTKKCLDKMNEFKEQGKTIFFISHSLSQVKSFCTKALWLHYGQVKEYGDIKEVVD-----HYDEFL 238
|
|
| ABCC_CFTR1 |
cd03291 |
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ... |
20-246 |
5.57e-09 |
|
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213258 [Multi-domain] Cd Length: 282 Bit Score: 55.25 E-value: 5.57e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 20 VLKGISIEANQGEVISILGSSGSGKSTLLRCSnLLEL-PDQGEIivggeaiemkpnrKGQNRPSNLKQIDRIRTqlgmvf 98
Cdd:cd03291 52 VLKNINLKIEKGEMLAITGSTGSGKTSLLMLI-LGELePSEGKI-------------KHSGRISFSSQFSWIMP------ 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 99 qnfnlwshKTVLENIIEAPVHVLKRPQAecVEHAEQLLEKVGLADKRHYYP-----AHLSGGQQQRAAIARALAMEPKVM 173
Cdd:cd03291 112 --------GTIKENIIFGVSYDEYRYKS--VVKACQLEEDITKFPEKDNTVlgeggITLSGGQRARISLARAVYKDADLY 181
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 497963481 174 LFDEPTSALDPELVGEVLR--VMRTLADEgmTMLVVTHEMDFAREvSNRIVFLHQGEIEEQGTpehvFTASQSAR 246
Cdd:cd03291 182 LLDSPFGYLDVFTEKEIFEscVCKLMANK--TRILVTSKMEHLKK-ADKILILHEGSSYFYGT----FSELQSLR 249
|
|
| ABC_RNaseL_inhibitor |
cd03222 |
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ... |
152-222 |
8.67e-09 |
|
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213189 [Multi-domain] Cd Length: 177 Bit Score: 53.73 E-value: 8.67e-09
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 497963481 152 LSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGM-TMLVVTHEMDFAREVSNRIV 222
Cdd:cd03222 72 LSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLNAARAIRRLSEEGKkTALVVEHDLAVLDYLSDRIH 143
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
31-238 |
8.74e-09 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 55.79 E-value: 8.74e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 31 GEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIemkpnrkgqnrpsnlkqidriRTQLGMVFQNFNLWSHKTVL 110
Cdd:TIGR01257 1965 GECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSI---------------------LTNISDVHQNMGYCPQFDAI 2023
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 111 ENIIEAPVHV-----LKRPQAECVEH-AEQLLEKVGLADKRHYYPAHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDP 184
Cdd:TIGR01257 2024 DDLLTGREHLylyarLRGVPAEEIEKvANWSIQSLGLSLYADRLAGTYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDP 2103
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 497963481 185 ELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHV 238
Cdd:TIGR01257 2104 QARRMLWNTIVSIIREGRAVVLTSHSMEECEALCTRLAIMVKGAFQCLGTIQHL 2157
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
20-227 |
1.10e-08 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 55.30 E-value: 1.10e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 20 VLKGISIEANQGEVISILGSSGSGKSTLLrcsnllelpdqgeIIVGGEAIEMKPNRKGQNRPSNLKQIDRIRTqlgmvfq 99
Cdd:TIGR01271 441 VLKNISFKLEKGQLLAVAGSTGSGKSSLL-------------MMIMGELEPSEGKIKHSGRISFSPQTSWIMP------- 500
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 100 nfnlwshKTVLENIIEAPVHVLKRPQAecVEHAEQLLEKVGLADKRHYYP-----AHLSGGQQQRAAIARALAMEPKVML 174
Cdd:TIGR01271 501 -------GTIKDNIIFGLSYDEYRYTS--VIKACQLEEDIALFPEKDKTVlgeggITLSGGQRARISLARAVYKDADLYL 571
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 497963481 175 FDEPTSALDPELVGEVLR--VMRTLADEgmTMLVVTHEMDFAREvSNRIVFLHQG 227
Cdd:TIGR01271 572 LDSPFTHLDVVTEKEIFEscLCKLMSNK--TRILVTSKLEHLKK-ADKILLLHEG 623
|
|
| PLN03140 |
PLN03140 |
ABC transporter G family member; Provisional |
18-210 |
1.40e-08 |
|
ABC transporter G family member; Provisional
Pssm-ID: 215599 [Multi-domain] Cd Length: 1470 Bit Score: 55.24 E-value: 1.40e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 18 LDVLKGISIEANQGEVISILGSSGSGKSTLLrcsNLLELPDQGEIIVGGEAIEMKPNRKgqnrpsnlKQIDRIRtqlGMV 97
Cdd:PLN03140 893 LQLLREVTGAFRPGVLTALMGVSGAGKTTLM---DVLAGRKTGGYIEGDIRISGFPKKQ--------ETFARIS---GYC 958
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 98 FQNFNLWSHKTVLENIIEA-----PVHVLKRPQAECVEHAEQLLEKVGLADKRHYYPA--HLSGGQQQRAAIARALAMEP 170
Cdd:PLN03140 959 EQNDIHSPQVTVRESLIYSaflrlPKEVSKEEKMMFVDEVMELVELDNLKDAIVGLPGvtGLSTEQRKRLTIAVELVANP 1038
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 497963481 171 KVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHE 210
Cdd:PLN03140 1039 SIIFMDEPTSGLDARAAAIVMRTVRNTVDTGRTVVCTIHQ 1078
|
|
| ABCG_PDR_domain2 |
cd03232 |
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ... |
16-210 |
1.42e-08 |
|
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213199 [Multi-domain] Cd Length: 192 Bit Score: 53.02 E-value: 1.42e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 16 GSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCsnLLELPDQGeiIVGGEaieMKPNrkGQNRPSNLkqidriRTQLG 95
Cdd:cd03232 18 GKRQLLNNISGYVKPGTLTALMGESGAGKTTLLDV--LAGRKTAG--VITGE---ILIN--GRPLDKNF------QRSTG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 96 MVFQNfnlwshktvleniieaPVHVLKRPQAECVEHAEQLLEkvgladkrhyypahLSGGQQQRAAIARALAMEPKVMLF 175
Cdd:cd03232 83 YVEQQ----------------DVHSPNLTVREALRFSALLRG--------------LSVEQRKRLTIGVELAAKPSILFL 132
|
170 180 190
....*....|....*....|....*....|....*
gi 497963481 176 DEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHE 210
Cdd:cd03232 133 DEPTSGLDSQAAYNIVRFLKKLADSGQAILCTIHQ 167
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
20-209 |
1.57e-08 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 54.74 E-value: 1.57e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 20 VLKGISIEANQGEVISILGSSGSGKSTLLRcsnllelpdqgeIIVG------GEAIEMkPNRKgqnrpsnlkqidrirtq 93
Cdd:PRK11819 22 ILKDISLSFFPGAKIGVLGLNGAGKSTLLR------------IMAGvdkefeGEARPA-PGIK----------------- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 94 LGMVFQNFNLWSHKTVLENIIEA---PVHVLKRPQ------AECVEHAEQLLEKVG-LADK------------------- 144
Cdd:PRK11819 72 VGYLPQEPQLDPEKTVRENVEEGvaeVKAALDRFNeiyaayAEPDADFDALAAEQGeLQEIidaadawdldsqleiamda 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 497963481 145 -RhyYP------AHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDPElvgEVLRVMRTLADEGMTMLVVTH 209
Cdd:PRK11819 152 lR--CPpwdakvTKLSGGERRRVALCRLLLEKPDMLLLDEPTNHLDAE---SVAWLEQFLHDYPGTVVAVTH 218
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
153-225 |
1.23e-07 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 52.17 E-value: 1.23e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 497963481 153 SGGQQQRAAIARALAMEPKVMLFDEPTSALDpelVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLH 225
Cdd:PLN03073 346 SGGWRMRIALARALFIEPDLLLLDEPTNHLD---LHAVLWLETYLLKWPKTFIVVSHAREFLNTVVTDILHLH 415
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
20-197 |
1.23e-07 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 52.22 E-value: 1.23e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 20 VLKGISIEANQGEVISILGSSGSGKSTLLrcSNLLELPD-QGEIIVGG---EAIEMKPNRKGqnrpsnlkqidrirtqLG 95
Cdd:TIGR01271 1234 VLQDLSFSVEGGQRVGLLGRTGSGKSTLL--SALLRLLStEGEIQIDGvswNSVTLQTWRKA----------------FG 1295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 96 MVFQNFNLWShKTVLENIieapvhvlkRPQAECV-EHAEQLLEKVGLADKRHYYPAH-----------LSGGQQQRAAIA 163
Cdd:TIGR01271 1296 VIPQKVFIFS-GTFRKNL---------DPYEQWSdEEIWKVAEEVGLKSVIEQFPDKldfvlvdggyvLSNGHKQLMCLA 1365
|
170 180 190
....*....|....*....|....*....|....
gi 497963481 164 RALAMEPKVMLFDEPTSALDPeLVGEVLRvmRTL 197
Cdd:TIGR01271 1366 RSILSKAKILLLDEPSAHLDP-VTLQIIR--KTL 1396
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
25-238 |
1.59e-07 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 51.55 E-value: 1.59e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 25 SIEANQGEVISILGSSGSGKSTLLRCsnllelpdqgeiiVGGEAIEMKPNRKGQ-NRPSNL--KQIDRIRTQlgmVFQ-- 99
Cdd:PRK10938 23 SLTLNAGDSWAFVGANGSGKSALARA-------------LAGELPLLSGERQSQfSHITRLsfEQLQKLVSD---EWQrn 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 100 NFNLWSH------KTVLENIIEApvhvLKRPQAeCVEHAEQLLEKvGLADKRHYYpahLSGGQQQRAAIARALAMEPKVM 173
Cdd:PRK10938 87 NTDMLSPgeddtgRTTAEIIQDE----VKDPAR-CEQLAQQFGIT-ALLDRRFKY---LSTGETRKTLLCQALMSEPDLL 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 497963481 174 LFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHV 238
Cdd:PRK10938 158 ILDEPFDGLDVASRQQLAELLASLHQSGITLVLVLNRFDEIPDFVQFAGVLADCTLAETGEREEI 222
|
|
| PRK00635 |
PRK00635 |
excinuclease ABC subunit A; Provisional |
150-244 |
3.84e-07 |
|
excinuclease ABC subunit A; Provisional
Pssm-ID: 234806 [Multi-domain] Cd Length: 1809 Bit Score: 50.98 E-value: 3.84e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 150 AHLSGGQQQRAAIARALAMEPK--VMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHE---MDFArevsNRIV-- 222
Cdd:PRK00635 475 ATLSGGEQERTALAKHLGAELIgiTYILDEPSIGLHPQDTHKLINVIKKLRDQGNTVLLVEHDeqmISLA----DRIIdi 550
|
90 100
....*....|....*....|....*.
gi 497963481 223 ----FLHQGEIEEQGTPEHVFTASQS 244
Cdd:PRK00635 551 gpgaGIFGGEVLFNGSPREFLAKSDS 576
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
5-62 |
4.22e-07 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 50.28 E-value: 4.22e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 497963481 5 AISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRC-SNLLElPDQGEI 62
Cdd:PRK15064 319 ALEVENLTKGFDNGPLFKNLNLLLEAGERLAIIGENGVGKTTLLRTlVGELE-PDSGTV 376
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
19-238 |
5.33e-07 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 50.49 E-value: 5.33e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 19 DVLKGISIEANQGEVISILGSSGSGKSTLLR--CSNLlelpDQGEIIVGGEAI-------EMKPNRKGQnrpsnlkqidr 89
Cdd:TIGR00956 75 DILKPMDGLIKPGELTVVLGRPGSGCSTLLKtiASNT----DGFHIGVEGVITydgitpeEIKKHYRGD----------- 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 90 irtqlgMVF--QNFNLWSHKTVLENIIEAPVhvLKRPQaecvEHAEQLLEKVGLADKRHYYPA-----H----------- 151
Cdd:TIGR00956 140 ------VVYnaETDVHFPHLTVGETLDFAAR--CKTPQ----NRPDGVSREEYAKHIADVYMAtyglsHtrntkvgndfv 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 152 --LSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADE-GMTMLVVTHE-MDFAREVSNRIVFLHQG 227
Cdd:TIGR00956 208 rgVSGGERKRVSIAEASLGGAKIQCWDNATRGLDSATALEFIRALKTSANIlDTTPLVAIYQcSQDAYELFDKVIVLYEG 287
|
250
....*....|.
gi 497963481 228 EIEEQGTPEHV 238
Cdd:TIGR00956 288 YQIYFGPADKA 298
|
|
| PRK13546 |
PRK13546 |
teichoic acids export ABC transporter ATP-binding subunit TagH; |
5-238 |
5.63e-07 |
|
teichoic acids export ABC transporter ATP-binding subunit TagH;
Pssm-ID: 184131 [Multi-domain] Cd Length: 264 Bit Score: 49.43 E-value: 5.63e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 5 AISLRNIHKSFGSLDvlkGISIEANQGEVISILGSSGSGKSTLlrcSNLLE---LPDQGEIIVGGEAIEMKPNrKGQNrp 81
Cdd:PRK13546 27 ALIPKHKNKTFFALD---DISLKAYEGDVIGLVGINGSGKSTL---SNIIGgslSPTVGKVDRNGEVSVIAIS-AGLS-- 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 82 SNLKQIDRIrtQLGMVFQNFNLWSHKTVLENIIEApvhvlkrpqAECVEHAEQLLEKvgladkrhyypahLSGGQQQRAA 161
Cdd:PRK13546 98 GQLTGIENI--EFKMLCMGFKRKEIKAMTPKIIEF---------SELGEFIYQPVKK-------------YSSGMRAKLG 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 497963481 162 IARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEIEEQGTPEHV 238
Cdd:PRK13546 154 FSINITVNPDILVIDEALSVGDQTFAQKCLDKIYEFKEQNKTIFFVSHNLGQVRQFCTKIAWIEGGKLKDYGELDDV 230
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
152-229 |
5.72e-07 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 49.79 E-value: 5.72e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 152 LSGGQQQRAAIARALAMEPKVMLFDEPTSALDpelVG---EVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGE 228
Cdd:NF040905 405 LSGGNQQKVVLSKWLFTDPDVLILDEPTRGID---VGakyEIYTIINELAAEGKGVIVISSELPELLGMCDRIYVMNEGR 481
|
.
gi 497963481 229 I 229
Cdd:NF040905 482 I 482
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
6-185 |
6.39e-07 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 49.93 E-value: 6.39e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVgGEAIEmkpnrkgqnrpsnLK 85
Cdd:TIGR03719 323 IEAENLTKAFGDKLLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEI-GETVK-------------LA 388
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 86 QIDRIRTQLGmvfqnfnlwSHKTVLENIIEAPVHVL--KR---PQAEC----VEHAEQlLEKVGLadkrhyypahLSGGQ 156
Cdd:TIGR03719 389 YVDQSRDALD---------PNKTVWEEISGGLDIIKlgKReipSRAYVgrfnFKGSDQ-QKKVGQ----------LSGGE 448
|
170 180
....*....|....*....|....*....
gi 497963481 157 QQRAAIARALAMEPKVMLFDEPTSALDPE 185
Cdd:TIGR03719 449 RNRVHLAKTLKSGGNVLLLDEPTNDLDVE 477
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
152-229 |
7.49e-07 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 49.73 E-value: 7.49e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 497963481 152 LSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREVSNRIVFLHQGEI 229
Cdd:PRK10982 392 LSGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKFEIYQLIAELAKKDKGIIIISSEMPELLGITDRILVMSNGLV 469
|
|
| ABC_UvrA_I |
cd03270 |
ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair ... |
21-233 |
1.08e-06 |
|
ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213237 [Multi-domain] Cd Length: 226 Bit Score: 48.02 E-value: 1.08e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 21 LKGISIEANQGEVISILGSSGSGKSTLL---------------------RCSNLLELPDQGEIIVGGEAIEMKPNRKGQN 79
Cdd:cd03270 11 LKNVDVDIPRNKLVVITGVSGSGKSSLAfdtiyaegqrryveslsayarQFLGQMDKPDVDSIEGLSPAIAIDQKTTSRN 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 80 RPSNLKQIDRIRTQLGMVFqnfnlwshktvleniieAPVHVLKRPQaecvehaeqLLEKVGLADKRHYYPAH-LSGGQQQ 158
Cdd:cd03270 91 PRSTVGTVTEIYDYLRLLF-----------------ARVGIRERLG---------FLVDVGLGYLTLSRSAPtLSGGEAQ 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 159 RAAIARALAMEPKVML--FDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREvSNRIVFL------HQGEIE 230
Cdd:cd03270 145 RIRLATQIGSGLTGVLyvLDEPSIGLHPRDNDRLIETLKRLRDLGNTVLVVEHDEDTIRA-ADHVIDIgpgagvHGGEIV 223
|
...
gi 497963481 231 EQG 233
Cdd:cd03270 224 AQG 226
|
|
| ABCC_CFTR2 |
cd03289 |
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ... |
20-212 |
1.65e-06 |
|
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213256 [Multi-domain] Cd Length: 275 Bit Score: 47.93 E-value: 1.65e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 20 VLKGISIEANQGEVISILGSSGSGKSTLLrcSNLLELPD-QGEIIVGGEAIEMKPnrkgqnrpsnlkqIDRIRTQLGMVF 98
Cdd:cd03289 19 VLENISFSISPGQRVGLLGRTGSGKSTLL--SAFLRLLNtEGDIQIDGVSWNSVP-------------LQKWRKAFGVIP 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 99 QNFNLWShKTVLENIIEAPVHvlkrpqaeCVEHAEQLLEKVGLADKRHYYPAH-----------LSGGQQQRAAIARALA 167
Cdd:cd03289 84 QKVFIFS-GTFRKNLDPYGKW--------SDEEIWKVAEEVGLKSVIEQFPGQldfvlvdggcvLSHGHKQLMCLARSVL 154
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 497963481 168 MEPKVMLFDEPTSALDPeLVGEVLRVMRTLADEGMTMLVVTHEMD 212
Cdd:cd03289 155 SKAKILLLDEPSAHLDP-ITYQVIRKTLKQAFADCTVILSEHRIE 198
|
|
| uvra |
TIGR00630 |
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ... |
152-244 |
2.08e-06 |
|
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273184 [Multi-domain] Cd Length: 925 Bit Score: 48.47 E-value: 2.08e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 152 LSGGQQQRAAIARALAME-PKVM-LFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFAREvSNRIVFL----- 224
Cdd:TIGR00630 489 LSGGEAQRIRLATQIGSGlTGVLyVLDEPSIGLHQRDNRRLINTLKRLRDLGNTLIVVEHDEDTIRA-ADYVIDIgpgag 567
|
90 100
....*....|....*....|.
gi 497963481 225 -HQGEIEEQGTPEHVFTASQS 244
Cdd:TIGR00630 568 eHGGEVVASGTPEEILANPDS 588
|
|
| ABC_Class2 |
cd03227 |
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ... |
152-214 |
2.19e-06 |
|
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.
Pssm-ID: 213194 [Multi-domain] Cd Length: 162 Bit Score: 46.58 E-value: 2.19e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 497963481 152 LSGGQQQRAAIARALAMEPK----VMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFA 214
Cdd:cd03227 78 LSGGEKELSALALILALASLkprpLYILDEIDRGLDPRDGQALAEAILEHLVKGAQVIVITHLPELA 144
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
5-252 |
2.43e-06 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 48.20 E-value: 2.43e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 5 AISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLrcsNLL---ELPDQGEIIVGGEAIemkpnRKGQNRP 81
Cdd:NF033858 1 VARLEGVSHRYGKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLL---SLIagaRKIQQGRVEVLGGDM-----ADARHRR 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 82 SNLKQIDRIRTQLGMvfqnfNLWSHKTVLENIieapvHVLKR----PQAECVEHAEQLLEKVGLAD--KRhyyPA-HLSG 154
Cdd:NF033858 73 AVCPRIAYMPQGLGK-----NLYPTLSVFENL-----DFFGRlfgqDAAERRRRIDELLRATGLAPfaDR---PAgKLSG 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 155 GQQQRAAIARALAMEPKVMLFDEPTSALDP-------ELVGEvLRVMRtladEGMTMLVVTHEMDFArEVSNRIVFLHQG 227
Cdd:NF033858 140 GMKQKLGLCCALIHDPDLLILDEPTTGVDPlsrrqfwELIDR-IRAER----PGMSVLVATAYMEEA-ERFDWLVAMDAG 213
|
250 260
....*....|....*....|....*.
gi 497963481 228 EIEEQGTPEHVFTASQSARFRQ-FIA 252
Cdd:NF033858 214 RVLATGTPAELLARTGADTLEAaFIA 239
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
30-224 |
4.12e-06 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 45.44 E-value: 4.12e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 30 QGEVISILGSSGSGKSTLLRC-SNLLELPDQGEIIVGGEAIEmkpnrkgqnrpsnlkqidrirtqlgmvfqnfnlwshkt 108
Cdd:smart00382 1 PGEVILIVGPPGSGKTTLARAlARELGPPGGGVIYIDGEDIL-------------------------------------- 42
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 109 vleniieapvhvlkrpqaecvehaeQLLEKVGLADKRHYYPAHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVG 188
Cdd:smart00382 43 -------------------------EEVLDQLLLIIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEA 97
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 497963481 189 EVLRVMRTLADEGM------TMLVVTH------EMDFAREVSNRIVFL 224
Cdd:smart00382 98 LLLLLEELRLLLLLkseknlTVILTTNdekdlgPALLRRRFDRRIVLL 145
|
|
| 3a01203 |
TIGR00954 |
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ... |
152-209 |
5.76e-06 |
|
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 273360 [Multi-domain] Cd Length: 659 Bit Score: 47.05 E-value: 5.76e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 497963481 152 LSGGQQQRAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRtlaDEGMTMLVVTH 209
Cdd:TIGR00954 583 LSGGEKQRIAMARLFYHKPQFAILDECTSAVSVDVEGYMYRLCR---EFGITLFSVSH 637
|
|
| PTZ00243 |
PTZ00243 |
ABC transporter; Provisional |
20-233 |
8.24e-06 |
|
ABC transporter; Provisional
Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 46.70 E-value: 8.24e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 20 VLKGISIEANQGEVISILGSSGSGKSTLLRcsnllELPDQGEIIVGGEAIEmkpnrkgqnrpsnlKQIDRIRTQLGMVfq 99
Cdd:PTZ00243 675 LLRDVSVSVPRGKLTVVLGATGSGKSTLLQ-----SLLSQFEISEGRVWAE--------------RSIAYVPQQAWIM-- 733
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 100 nfnlwsHKTVLENII------EAPVH-VLKRPQAEcvehAEQLLEKVGLADKRHYYPAHLSGGQQQRAAIARALAMEPKV 172
Cdd:PTZ00243 734 ------NATVRGNILffdeedAARLAdAVRVSQLE----ADLAQLGGGLETEIGEKGVNLSGGQKARVSLARAVYANRDV 803
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 497963481 173 MLFDEPTSALDPElVGEvlRVMRTL---ADEGMTMLVVTHEMDFArEVSNRIVFLHQGEIEEQG 233
Cdd:PTZ00243 804 YLLDDPLSALDAH-VGE--RVVEECflgALAGKTRVLATHQVHVV-PRADYVVALGDGRVEFSG 863
|
|
| ABCC_SUR2 |
cd03288 |
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ... |
20-251 |
1.06e-05 |
|
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213255 [Multi-domain] Cd Length: 257 Bit Score: 45.67 E-value: 1.06e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 20 VLKGISIEANQGEVISILGSSGSGKSTL-LRCSNLLELPDqGEIIVGGEAIEMKPnrkgqnrpsnlkqIDRIRTQLGMVF 98
Cdd:cd03288 36 VLKHVKAYIKPGQKVGICGRTGSGKSSLsLAFFRMVDIFD-GKIVIDGIDISKLP-------------LHTLRSRLSIIL 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 99 QNFNLWShKTVLENIieapvhvlkRPQAECVEhaEQLLEKVGLADKRHYYPA--------------HLSGGQQQRAAIAR 164
Cdd:cd03288 102 QDPILFS-GSIRFNL---------DPECKCTD--DRLWEALEIAQLKNMVKSlpggldavvteggeNFSVGQRQLFCLAR 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 165 ALAMEPKVMLFDEPTSALD---PELVGEVlrVMRTLADEgmTMLVVTHEMDFAREvSNRIVFLHQGEIEEQGTPEHVFtA 241
Cdd:cd03288 170 AFVRKSSILIMDEATASIDmatENILQKV--VMTAFADR--TVVTIAHRVSTILD-ADLVLVLSRGILVECDTPENLL-A 243
|
250
....*....|
gi 497963481 242 SQSARFRQFI 251
Cdd:cd03288 244 QEDGVFASLV 253
|
|
| PTZ00243 |
PTZ00243 |
ABC transporter; Provisional |
20-244 |
1.10e-05 |
|
ABC transporter; Provisional
Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 46.31 E-value: 1.10e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 20 VLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVGGEAIEMKPNRKgqnrpsnlkqidrIRTQLGMVFQ 99
Cdd:PTZ00243 1325 VLRGVSFRIAPREKVGIVGRTGSGKSTLLLTFMRMVEVCGGEIRVNGREIGAYGLRE-------------LRRQFSMIPQ 1391
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 100 NFNLWShKTVLENI---IEA-PVHVLKrpQAECVEHAEQLLEKVGLADKR------HYypahlSGGQQQRAAIARALAME 169
Cdd:PTZ00243 1392 DPVLFD-GTVRQNVdpfLEAsSAEVWA--ALELVGLRERVASESEGIDSRvleggsNY-----SVGQRQLMCMARALLKK 1463
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 497963481 170 -PKVMLFDEPTSALDPELVGEVLRVMRTlADEGMTMLVVTHEMDFAREVSNRIVFLHqGEIEEQGTPEHVFTASQS 244
Cdd:PTZ00243 1464 gSGFILMDEATANIDPALDRQIQATVMS-AFSAYTVITIAHRLHTVAQYDKIIVMDH-GAVAEMGSPRELVMNRQS 1537
|
|
| UvrA |
COG0178 |
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair]; |
134-238 |
1.30e-05 |
|
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];
Pssm-ID: 439948 [Multi-domain] Cd Length: 941 Bit Score: 45.79 E-value: 1.30e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 134 QLLEKVGLAdkrhyY-----PAH-LSGGQQQRAAIARALAMEPK---VMLFDEPTSALDPELVGEVLRVMRTLADEGMTM 204
Cdd:COG0178 808 QTLQDVGLG-----YiklgqPATtLSGGEAQRVKLASELSKRSTgktLYILDEPTTGLHFHDIRKLLEVLHRLVDKGNTV 882
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 497963481 205 LVVTHEMDFAReVSNRIVFL------HQGEIEEQGTPEHV 238
Cdd:COG0178 883 VVIEHNLDVIK-TADWIIDLgpeggdGGGEIVAEGTPEEV 921
|
|
| PRK10636 |
PRK10636 |
putative ABC transporter ATP-binding protein; Provisional |
3-230 |
1.70e-05 |
|
putative ABC transporter ATP-binding protein; Provisional
Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 45.55 E-value: 1.70e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 3 TPAISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRcsnLL--EL-PDQGEIivgGEAIEMKPNRKGQN 79
Cdd:PRK10636 310 NPLLKMEKVSAGYGDRIILDSIKLNLVPGSRIGLLGRNGAGKSTLIK---LLagELaPVSGEI---GLAKGIKLGYFAQH 383
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 80 rpsnlkQIDRIRTQlgmvfqnfnlwshktvleniiEAPVHVLKR--PQaecvEHAEQLLEKVG----LADKRHYYPAHLS 153
Cdd:PRK10636 384 ------QLEFLRAD---------------------ESPLQHLARlaPQ----ELEQKLRDYLGgfgfQGDKVTEETRRFS 432
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 154 GGQQQRAAIARALAMEPKVMLFDEPTSALDPElvgevlrvMRTLADEGM-----TMLVVTHEMDFAREVSNRIVFLHQGE 228
Cdd:PRK10636 433 GGEKARLVLALIVWQRPNLLLLDEPTNHLDLD--------MRQALTEALidfegALVVVSHDRHLLRSTTDDLYLVHDGK 504
|
..
gi 497963481 229 IE 230
Cdd:PRK10636 505 VE 506
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
8-231 |
3.55e-05 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 44.56 E-value: 3.55e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 8 LRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRcsnLL--EL-PDQGEIIVGGEaIEmkpnrkgqnrpsnL 84
Cdd:PRK11147 322 MENVNYQIDGKQLVKDFSAQVQRGDKIALIGPNGCGKTTLLK---LMlgQLqADSGRIHCGTK-LE-------------V 384
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 85 KQIDRIRTQLGmvfqnfnlwSHKTVLENIIEAP--VHVLKRPQaecveHAEQLLEKVGLADKRHYYPAH-LSGGQQQRAA 161
Cdd:PRK11147 385 AYFDQHRAELD---------PEKTVMDNLAEGKqeVMVNGRPR-----HVLGYLQDFLFHPKRAMTPVKaLSGGERNRLL 450
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 497963481 162 IARALAMEPKVMLFDEPTSALDPELVgEVLRVMrtLADEGMTMLVVTHEMDFareVSNRI----VFLHQGEIEE 231
Cdd:PRK11147 451 LARLFLKPSNLLILDEPTNDLDVETL-ELLEEL--LDSYQGTVLLVSHDRQF---VDNTVtecwIFEGNGKIGR 518
|
|
| ABC_Rad50 |
cd03240 |
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ... |
6-215 |
3.88e-05 |
|
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.
Pssm-ID: 213207 [Multi-domain] Cd Length: 204 Bit Score: 43.36 E-value: 3.88e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIhKSF---GSLDVLKGISIeanqgevisILGSSGSGKSTLLRCSNLlelpdqgeIIVGgeaiEMKPNRKGQNRPS 82
Cdd:cd03240 4 LSIRNI-RSFherSEIEFFSPLTL---------IVGQNGAGKTTIIEALKY--------ALTG----ELPPNSKGGAHDP 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 83 NLKQIDRIRTQLGMVFQNFNlwSHKTVLENIIEAPVHVLKRPQAECvehAEQLLEKVGLadkrhyypahLSGGQQQRAAI 162
Cdd:cd03240 62 KLIREGEVRAQVKLAFENAN--GKKYTITRSLAILENVIFCHQGES---NWPLLDMRGR----------CSGGEKVLASL 126
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 497963481 163 ARALAMepkVMLF---------DEPTSALDPELVGEVLR--VMRTLADEGMTMLVVTHEMDFAR 215
Cdd:cd03240 127 IIRLAL---AETFgsncgilalDEPTTNLDEENIEESLAeiIEERKSQKNFQLIVITHDEELVD 187
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
6-185 |
4.43e-05 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 44.34 E-value: 4.43e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRCSNLLELPDQGEIIVgGEAIemkpnrkgqnrpsnlk 85
Cdd:PRK11819 325 IEAENLSKSFGDRLLIDDLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTIKI-GETV---------------- 387
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 86 qidrirtQLGMVFQNF-NLWSHKTVLENIIEApVHVLKRPQAECVEHA-----------EQllEKVGLadkrhyypahLS 153
Cdd:PRK11819 388 -------KLAYVDQSRdALDPNKTVWEEISGG-LDIIKVGNREIPSRAyvgrfnfkggdQQ--KKVGV----------LS 447
|
170 180 190
....*....|....*....|....*....|..
gi 497963481 154 GGQQQRAAIARALAMEPKVMLFDEPTSALDPE 185
Cdd:PRK11819 448 GGERNRLHLAKTLKQGGNVLLLDEPTNDLDVE 479
|
|
| YbjD |
COG3593 |
Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM ... |
6-251 |
4.45e-05 |
|
Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM domains [Replication, recombination and repair];
Pssm-ID: 442812 [Multi-domain] Cd Length: 359 Bit Score: 43.84 E-value: 4.45e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNiHKSFGSLDV--LKGISIeanqgevisILGSSGSGKSTLLRCSNLL------------ELPDQGEIIVGGEAIEM 71
Cdd:COG3593 6 IKIKN-FRSIKDLSIelSDDLTV---------LVGENNSGKSSILEALRLLlgpsssrkfdeeDFYLGDDPDLPEIEIEL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 72 K---------PNRKGQNRPSNLKQ-IDRIRTQLGMVFQNFNLWSHKTVLENIIEAPVHVlkRPQAECVEHAEQLLeKVGL 141
Cdd:COG3593 76 TfgsllsrllRLLLKEEDKEELEEaLEELNEELKEALKALNELLSEYLKELLDGLDLEL--ELSLDELEDLLKSL-SLRI 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 142 ADKRHYYPAHLSGGQQQRAAIARALAM-------EPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEMDFA 214
Cdd:COG3593 153 EDGKELPLDRLGSGFQRLILLALLSALaelkrapANPILLIEEPEAHLHPQAQRRLLKLLKELSEKPNQVIITTHSPHLL 232
|
250 260 270
....*....|....*....|....*....|....*...
gi 497963481 215 REVS-NRIVFLHQGEIEEQGTPEHVFTASQSARFRQFI 251
Cdd:COG3593 233 SEVPlENIRRLRRDSGGTTSTKLIDLDDEDLRKLLRYL 270
|
|
| PRK13541 |
PRK13541 |
cytochrome c biogenesis protein CcmA; Provisional |
36-185 |
6.08e-05 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184128 [Multi-domain] Cd Length: 195 Bit Score: 42.55 E-value: 6.08e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 36 ILGSSGSGKSTLLRCSNLLELPDQGEIIVggeaiemkpnrkgqnRPSNLKQIDR-----IRTQLGM-----VFQNFNLWS 105
Cdd:PRK13541 31 IKGANGCGKSSLLRMIAGIMQPSSGNIYY---------------KNCNINNIAKpyctyIGHNLGLklemtVFENLKFWS 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 106 HKTVLENIIEAPVHVLKRPQaecvehaeqllekvgLADKRHYypaHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDPE 185
Cdd:PRK13541 96 EIYNSAETLYAAIHYFKLHD---------------LLDEKCY---SLSSGMQKIVAIARLIACQSDLWLLDEVETNLSKE 157
|
|
| AAA_21 |
pfam13304 |
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being ... |
149-209 |
9.16e-05 |
|
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.
Pssm-ID: 433102 [Multi-domain] Cd Length: 303 Bit Score: 42.76 E-value: 9.16e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 497963481 149 PAHLSGGQQQ---RAAIARALAMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTH 209
Cdd:pfam13304 234 AFELSDGTKRllaLLAALLSALPKGGLLLIDEPESGLHPKLLRRLLELLKELSRNGAQLILTTH 297
|
|
| PRK00635 |
PRK00635 |
excinuclease ABC subunit A; Provisional |
152-211 |
1.69e-04 |
|
excinuclease ABC subunit A; Provisional
Pssm-ID: 234806 [Multi-domain] Cd Length: 1809 Bit Score: 42.51 E-value: 1.69e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 497963481 152 LSGGQQQRAAIARAL---AMEPKVMLFDEPTSALDPELVGEVLRVMRTLADEGMTMLVVTHEM 211
Cdd:PRK00635 810 LSGGEIQRLKLAYELlapSKKPTLYVLDEPTTGLHTHDIKALIYVLQSLTHQGHTVVIIEHNM 872
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
6-249 |
1.75e-04 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 42.19 E-value: 1.75e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNIHKSFGSLDVLKGISIEANQGEVISILGSSGSGKSTLLRcsnllelpdqgeiIVGGE------AIEMKPNrkgqN 79
Cdd:PRK15064 2 LSTANITMQFGAKPLFENISVKFGGGNRYGLIGANGCGKSTFMK-------------ILGGDlepsagNVSLDPN----E 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 80 RPSNLKQidrirTQLGmvFQNFN-----------LWSHKTVLENIIEAP-------VHVlkrpqAEC-VEHAE------- 133
Cdd:PRK15064 65 RLGKLRQ-----DQFA--FEEFTvldtvimghteLWEVKQERDRIYALPemseedgMKV-----ADLeVKFAEmdgytae 132
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 134 ----QLLEKVGLADKRHYYP-AHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDpelvgevLRVMRTLADE----GMTM 204
Cdd:PRK15064 133 aragELLLGVGIPEEQHYGLmSEVAPGWKLRVLLAQALFSNPDILLLDEPTNNLD-------INTIRWLEDVlnerNSTM 205
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 497963481 205 LVVTHEMDFAREVSNRIVFLHQGEIE-EQGTPEHVFTASQSARFRQ 249
Cdd:PRK15064 206 IIISHDRHFLNSVCTHMADLDYGELRvYPGNYDEYMTAATQARERL 251
|
|
| PRK10636 |
PRK10636 |
putative ABC transporter ATP-binding protein; Provisional |
132-231 |
2.61e-04 |
|
putative ABC transporter ATP-binding protein; Provisional
Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 42.08 E-value: 2.61e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 132 AEQLLEKVGLADKRHYYP-AHLSGGQQQRAAIARALAMEPKVMLFDEPTSALDpelVGEVLRVMRTLADEGMTMLVVTHE 210
Cdd:PRK10636 129 AASLLHGLGFSNEQLERPvSDFSGGWRMRLNLAQALICRSDLLLLDEPTNHLD---LDAVIWLEKWLKSYQGTLILISHD 205
|
90 100
....*....|....*....|.
gi 497963481 211 MDFAREVSNRIVFLHQGEIEE 231
Cdd:PRK10636 206 RDFLDPIVDKIIHIEQQSLFE 226
|
|
| uvrA |
PRK00349 |
excinuclease ABC subunit UvrA; |
134-247 |
3.09e-04 |
|
excinuclease ABC subunit UvrA;
Pssm-ID: 234734 [Multi-domain] Cd Length: 943 Bit Score: 41.60 E-value: 3.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 134 QLLEKVGLAdkrhyY-----PA-HLSGGQQQRAAIARALAMEPK---VMLFDEPTSALDPELVGEVLRVMRTLADEGMTM 204
Cdd:PRK00349 812 QTLVDVGLG-----YiklgqPAtTLSGGEAQRVKLAKELSKRSTgktLYILDEPTTGLHFEDIRKLLEVLHRLVDKGNTV 886
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 497963481 205 LVVTHEMDFAReVSNRIVFL------HQGEIEEQGTPEHVFTASQS--ARF 247
Cdd:PRK00349 887 VVIEHNLDVIK-TADWIIDLgpeggdGGGEIVATGTPEEVAKVEASytGRY 936
|
|
| SbcC |
COG0419 |
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]; |
6-209 |
5.83e-04 |
|
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];
Pssm-ID: 440188 [Multi-domain] Cd Length: 204 Bit Score: 39.99 E-value: 5.83e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 6 ISLRNihksFGSLDVLKGISIEANqgeVISILGSSGSGKSTLLRC----------------SNLLELPDQG-----EIIV 64
Cdd:COG0419 5 LRLEN----FRSYRDTETIDFDDG---LNLIVGPNGAGKSTILEAiryalygkarsrsklrSDLINVGSEEasvelEFEH 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497963481 65 GGEAIEMK-----PNRKGQNRPSNLKQIdrIRTQLGMvfqnfnlwshkTVLENIIEApvhvLKRPQAECVEHAEQLLEKV 139
Cdd:COG0419 78 GGKRYRIErrqgeFAEFLEAKPSERKEA--LKRLLGL-----------EIYEELKER----LKELEEALESALEELAELQ 140
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 497963481 140 GLADKR-----HYYPAH-LSGGQQQRAAIARALAmepkvMLFDepTSALDPELVGEVLRVMRTLAdegmtmlVVTH 209
Cdd:COG0419 141 KLKQEIlaqlsGLDPIEtLSGGERLRLALADLLS-----LILD--FGSLDEERLERLLDALEELA-------IITH 202
|
|
| |
