|
Name |
Accession |
Description |
Interval |
E-value |
| Gcl |
COG3960 |
Glyoxylate carboligase [Secondary metabolites biosynthesis, transport and catabolism]; |
2-578 |
0e+00 |
|
Glyoxylate carboligase [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443160 [Multi-domain] Cd Length: 588 Bit Score: 1270.36 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 2 PKMTAAAAAVEILKREGVDHAFGVPGAAINPFYAALRARGGIGHTLARHVEGASHMAEGYTRTAPGNIGVCVGTSGPAGT 81
Cdd:COG3960 1 ARMRAVDAAVAVLEKEGVTTAFGVPGAAINPFYSAMRKHGGIRHVLARHVEGASHMAEGYTRAKAGNIGVCIGTSGPAGT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 82 DMITGLYSASADSVPILCITGQAPVARLHKEDFQAVDISSIAQPVTKMAVTVLEPAQVPGAFQRAFHLMRSGRPGPVLID 161
Cdd:COG3960 81 DMITGLYSASADSIPILCITGQAPRARLHKEDFQAVDIESIAKPVTKWAVTVLEPAQVPRVFQQAFHLMRSGRPGPVLID 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 162 LPVDVQLAEIEFDPDTYEPMPLARPAATRAQAEKALAMLAAAERPLIVAGGGIVNADAAGLLVEFAELVDVPVVPTLMGW 241
Cdd:COG3960 161 LPIDVQMAEIEFDIDTYEPLPVYKPAATRAQIEKALDMLNAAERPLIVAGGGIINADASDLLVEFAELTGVPVIPTLMGW 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 242 GTIADDHPLMAGMVGLQAAHRYGNATMLEADFVLGIGNRWANRHTGGLDTYTRGRTFVHVDIEPTQIGRVFAPGYGIVSD 321
Cdd:COG3960 241 GSIPDDHPLMAGMVGLQTSHRYGNATLLASDFVLGIGNRWANRHTGSLDVYTKGRKFVHVDIEPTQIGRVFAPDLGIVSD 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 322 AGAALERFVEVARARKAAGTLPDRSEWVAQCRRRKQTLQRRTHFDDVPIKPQRVYEEMNRAFGPETRYVSAIGLSQIAAA 401
Cdd:COG3960 321 AKAALELFVEVARERKAAGKLPDRSAWAAECQERKRTMLRKTHFDNVPIKPQRVYEEMNKAFGRDTRYVSTIGLSQIAAA 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 402 QFLHVQQARHWINCGQAGPLGWTVPAALGVRVADPEAPVVAISGDYDFQFMLEELAVGAQFNLPYVHVVVNNSYLGLIRQ 481
Cdd:COG3960 401 QFLHVYKPRHWINCGQAGPLGWTIPAALGVVAADPDRPVVALSGDYDFQFMIEELAVGAQFKLPYIHVVVNNSYLGLIRQ 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 482 AQRGFDMDYCVQLSFENINAPELGAYGVDHVKVAEGLGCKAIRVHEPGDLLPAFEKAGNLAAEHQVPVVVEVILERVTNI 561
Cdd:COG3960 481 AQRGFDMDYCVQLAFENINAPELGGYGVDHVKVAEGLGCKAIRVTDPEEIAPAFEEAKALMAEHRVPVVVEVILERVTNI 560
|
570
....*....|....*..
gi 497628394 562 SMGTEIDGVAEFEALAE 578
Cdd:COG3960 561 SMGTEIDNVNEFEELAE 577
|
|
| PRK11269 |
PRK11269 |
glyoxylate carboligase; Provisional |
1-579 |
0e+00 |
|
glyoxylate carboligase; Provisional
Pssm-ID: 183066 [Multi-domain] Cd Length: 591 Bit Score: 1246.02 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 1 MPKMTAAAAAVEILKREGVDHAFGVPGAAINPFYAALRARGGIGHTLARHVEGASHMAEGYTRTAPGNIGVCVGTSGPAG 80
Cdd:PRK11269 1 MAKMRAVDAAVLVLEKEGVTTAFGVPGAAINPFYSAMRKHGGIRHILARHVEGASHMAEGYTRATAGNIGVCIGTSGPAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 81 TDMITGLYSASADSVPILCITGQAPVARLHKEDFQAVDISSIAQPVTKMAVTVLEPAQVPGAFQRAFHLMRSGRPGPVLI 160
Cdd:PRK11269 81 TDMITGLYSASADSIPILCITGQAPRARLHKEDFQAVDIESIAKPVTKWAVTVREPALVPRVFQQAFHLMRSGRPGPVLI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 161 DLPVDVQLAEIEFDPDTYEPMPLARPAATRAQAEKALAMLAAAERPLIVAGGGIVNADAAGLLVEFAELVDVPVVPTLMG 240
Cdd:PRK11269 161 DLPFDVQVAEIEFDPDTYEPLPVYKPAATRAQIEKALEMLNAAERPLIVAGGGVINADASDLLVEFAELTGVPVIPTLMG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 241 WGTIADDHPLMAGMVGLQAAHRYGNATMLEADFVLGIGNRWANRHTGGLDTYTRGRTFVHVDIEPTQIGRVFAPGYGIVS 320
Cdd:PRK11269 241 WGAIPDDHPLMAGMVGLQTSHRYGNATLLASDFVLGIGNRWANRHTGSVEVYTKGRKFVHVDIEPTQIGRVFGPDLGIVS 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 321 DAGAALERFVEVARARKAAGTLPDRSEWVAQCRRRKQTLQRRTHFDDVPIKPQRVYEEMNRAFGPETRYVSAIGLSQIAA 400
Cdd:PRK11269 321 DAKAALELLVEVAREWKAAGRLPDRSAWVADCQERKRTLLRKTHFDNVPIKPQRVYEEMNKAFGRDTCYVSTIGLSQIAA 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 401 AQFLHVQQARHWINCGQAGPLGWTVPAALGVRVADPEAPVVAISGDYDFQFMLEELAVGAQFNLPYVHVVVNNSYLGLIR 480
Cdd:PRK11269 401 AQFLHVYKPRHWINCGQAGPLGWTIPAALGVRAADPDRNVVALSGDYDFQFLIEELAVGAQFNLPYIHVLVNNAYLGLIR 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 481 QAQRGFDMDYCVQLSFENINAPELGAYGVDHVKVAEGLGCKAIRVHEPGDLLPAFEKAGNLAAEHQVPVVVEVILERVTN 560
Cdd:PRK11269 481 QAQRAFDMDYCVQLAFENINSPELNGYGVDHVKVAEGLGCKAIRVFKPEDIAPALEQAKALMAEFRVPVVVEVILERVTN 560
|
570
....*....|....*....
gi 497628394 561 ISMGTEIDGVAEFEALAEV 579
Cdd:PRK11269 561 ISMGTEIDAVNEFEELADN 579
|
|
| glyox_carbo_lig |
TIGR01504 |
glyoxylate carboligase; Glyoxylate carboligase, also called tartronate-semialdehyde synthase, ... |
3-578 |
0e+00 |
|
glyoxylate carboligase; Glyoxylate carboligase, also called tartronate-semialdehyde synthase, releases CO2 while synthesizing a single molecule of tartronate semialdehyde from two molecules of glyoxylate. It is a thiamine pyrophosphate-dependent enzyme, closely related in sequence to the large subunit of acetolactate synthase. In the D-glycerate pathway, part of allantoin degradation in the Enterobacteriaceae, tartronate semialdehyde is converted to D-glycerate and then 3-phosphoglycerate, a product of glycolysis and entry point in the general metabolism.
Pssm-ID: 213633 [Multi-domain] Cd Length: 588 Bit Score: 1044.16 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 3 KMTAAAAAVEILKREGVDHAFGVPGAAINPFYAALRARGGIGHTLARHVEGASHMAEGYTRTAPGNIGVCVGTSGPAGTD 82
Cdd:TIGR01504 2 RMRAVDAAVYVLEKEGITTAFGVPGAAINPFYSALKAHGGIRHILARHVEGASHMAEGYTRATAGNIGVCIGTSGPAGTD 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 83 MITGLYSASADSVPILCITGQAPVARLHKEDFQAVDISSIAQPVTKMAVTVLEPAQVPGAFQRAFHLMRSGRPGPVLIDL 162
Cdd:TIGR01504 82 MITGLYSASADSIPILCITGQAPRARLHKEDFQAVDIAAIAKPVSKMAVTVREAALVPRVLQQAFHLMRSGRPGPVLIDL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 163 PVDVQLAEIEFDPDTYEPMPLARPAATRAQAEKALAMLAAAERPLIVAGGGIVNADAAGLLVEFAELVDVPVVPTLMGWG 242
Cdd:TIGR01504 162 PFDVQVAEIEFDPDTYEPLPVYKPAATRAQIEKAVEMLNAAERPLIVAGGGVINADAADLLQEFAELTGVPVIPTLMGWG 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 243 TIADDHPLMAGMVGLQAAHRYGNATMLEADFVLGIGNRWANRHTGGLDTYTRGRTFVHVDIEPTQIGRVFAPGYGIVSDA 322
Cdd:TIGR01504 242 CIPDDHELMAGMVGLQTSHRYGNATLLESDFVFGIGNRWANRHTGSVDVYTEGRKFVHVDIEPTQIGRVFAPDLGIVSDA 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 323 GAALERFVEVARARKAAGTLPDRSEWVAQCRRRKQTLQRRTHFDDVPIKPQRVYEEMNRAFGPETRYVSAIGLSQIAAAQ 402
Cdd:TIGR01504 322 KAALKLLVEVAQELKKAGRLPDRSEWAADCQQRKRTLLRKTHFDNVPVKPQRVYEEMNKAFGRDVCYVTTIGLSQIAGAQ 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 403 FLHVQQARHWINCGQAGPLGWTVPAALGVRVADPEAPVVAISGDYDFQFMLEELAVGAQFNLPYVHVVVNNSYLGLIRQA 482
Cdd:TIGR01504 402 MLHVYKPRHWINCGQAGPLGWTIPAALGVCAADPKRNVVALSGDYDFQFMIEELAVGAQHNIPYIHVLVNNAYLGLIRQA 481
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 483 QRGFDMDYCVQLSFENINAPELGAYGVDHVKVAEGLGCKAIRVHEPGDLLPAFEKAGNLAAEHQVPVVVEVILERVTNIS 562
Cdd:TIGR01504 482 QRAFDMDYCVQLAFENINSSEVNGYGVDHVKVAEGLGCKAIRVFKPEEIAPAFEQAKALMAEHRVPVVVEVILERVTNIS 561
|
570
....*....|....*.
gi 497628394 563 MGTEIDGVAEFEALAE 578
Cdd:TIGR01504 562 MGSEIDNVVEFEDLAD 577
|
|
| IlvB |
COG0028 |
Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme [Amino ... |
2-565 |
0e+00 |
|
Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme [Amino acid transport and metabolism, Coenzyme transport and metabolism]; Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 439799 [Multi-domain] Cd Length: 548 Bit Score: 533.20 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 2 PKMTAAAAAVEILKREGVDHAFGVPGAAINPFYAALRARGGIGHTLARHVEGASHMAEGYTRTApGNIGVCVGTSGPAGT 81
Cdd:COG0028 1 MKMTGADALVEALEAEGVETVFGVPGGAILPLYDALRRQSGIRHILVRHEQGAAFMADGYARAT-GKPGVCLVTSGPGAT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 82 DMITGLYSASADSVPILCITGQAPVARLHKEDFQAVDISSIAQPVTKMAVTVLEPAQVPGAFQRAFHLMRSGRPGPVLID 161
Cdd:COG0028 80 NLVTGLADAYMDSVPVLAITGQVPTSLIGRGAFQEVDQVGLFRPITKWSYLVTDPEDLPEVLRRAFRIATSGRPGPVVLD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 162 LPVDVQLAEIEFDPDTYEPMPLA-RPAATRAQAEKALAMLAAAERPLIVAGGGIVNADAAGLLVEFAELVDVPVVPTLMG 240
Cdd:COG0028 160 IPKDVQAAEAEEEPAPPELRGYRpRPAPDPEAIEEAAELLAAAKRPVILAGGGARRAGAAEELRALAERLGAPVVTTLMG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 241 WGTIADDHPLMAGMVGLqAAHRYGNATMLEADFVLGIGNRWANRHTGGLDTYTRGRTFVHVDIEPTQIGRVFAPGYGIVS 320
Cdd:COG0028 240 KGAFPEDHPLYLGMLGM-HGTPAANEALAEADLVLAVGARFDDRVTGNWDEFAPDAKIIHIDIDPAEIGKNYPVDLPIVG 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 321 DAGAALERFVEVARARKaagtlPDRSEWVAQCRRRKQTLQRRTHFDDVPIKPQRVYEEMNRAFGPETRYVSAIGLSQIAA 400
Cdd:COG0028 319 DAKAVLAALLEALEPRA-----DDRAAWLARIAAWRAEYLAAYAADDGPIKPQRVIAALREALPDDAIVVTDVGQHQMWA 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 401 AQFLHVQQARHWINCGQAGPLGWTVPAALGVRVADPEAPVVAISGDYDFQFMLEELAVGAQFNLPYVHVVVNNSYLGLIR 480
Cdd:COG0028 394 ARYLRFRRPRRFLTSGGLGTMGYGLPAAIGAKLARPDRPVVAITGDGGFQMNLQELATAVRYGLPVKVVVLNNGGLGMVR 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 481 QAQRGFDMDYCVQLSFENInapelgaygvDHVKVAEGLGCKAIRVHEPGDLLPAFEKagnlAAEHQVPVVVEVILERVTN 560
Cdd:COG0028 474 QWQELFYGGRYSGTDLPNP----------DFAKLAEAFGAKGERVETPEELEAALEE----ALASDGPALIDVRVDPEEN 539
|
....*
gi 497628394 561 ISMGT 565
Cdd:COG0028 540 PPGAT 544
|
|
| acolac_lg |
TIGR00118 |
acetolactate synthase, large subunit, biosynthetic type; Two groups of proteins form ... |
4-561 |
2.31e-156 |
|
acetolactate synthase, large subunit, biosynthetic type; Two groups of proteins form acetolactate from two molecules of pyruvate. The type of acetolactate synthase described in this model also catalyzes the formation of acetohydroxybutyrate from pyruvate and 2-oxobutyrate, an early step in the branched chain amino acid biosynthesis; it is therefore also termed acetohydroxyacid synthase. In bacteria, this catalytic chain is associated with a smaller regulatory chain in an alpha2/beta2 heterotetramer. Acetolactate synthase is a thiamine pyrophosphate enzyme. In this type, FAD and Mg++ are also found. Several isozymes of this enzyme are found in E. coli K12, one of which contains a frameshift in the large subunit gene and is not expressed. [Amino acid biosynthesis, Pyruvate family]
Pssm-ID: 272915 [Multi-domain] Cd Length: 558 Bit Score: 459.57 E-value: 2.31e-156
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 4 MTAAAAAVEILKREGVDHAFGVPGAAINPFYAALRARGGIGHTLARHVEGASHMAEGYTRtAPGNIGVCVGTSGPAGTDM 83
Cdd:TIGR00118 1 MSGAEAIIESLKDEGVKTVFGYPGGAILPIYDALYNDSGIEHILVRHEQGAAHAADGYAR-ASGKVGVVLVTSGPGATNL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 84 ITGLYSASADSVPILCITGQAPVARLHKEDFQAVDISSIAQPVTKMAVTVLEPAQVPGAFQRAFHLMRSGRPGPVLIDLP 163
Cdd:TIGR00118 80 VTGIATAYMDSIPMVVFTGQVPTSLIGSDAFQEADILGITMPITKHSFQVKSAEDIPRIIKEAFHIATTGRPGPVLVDLP 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 164 VDVQLAEIEFDPDTYEPMPLARPAAT--RAQAEKALAMLAAAERPLIVAGGGIVNADAAGLLVEFAELVDVPVVPTLMGW 241
Cdd:TIGR00118 160 KDVTTAEIEYPYPEKVNLPGYRPTVKghPLQIKKAAELINLAKKPVILVGGGVIIAGASEELKELAERIQIPVTTTLMGL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 242 GTIADDHPLMAGMVGLQAAhRYGNATMLEADFVLGIGNRWANRHTGGLDTYTRGRTFVHVDIEPTQIGRVFAPGYGIVSD 321
Cdd:TIGR00118 240 GSFPEDHPLSLGMLGMHGT-KTANLAVHECDLIIAVGARFDDRVTGNLAKFAPNAKIIHIDIDPAEIGKNVRVDIPIVGD 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 322 AGAALERFVEVARARKAagtlPDRSEWVAQCRRRKQTLQRRTHFDDVPIKPQRVYEEMNRAFGPETRYVSAIGLSQIAAA 401
Cdd:TIGR00118 319 ARNVLEELLKKLFELKE----RKESAWLEQINKWKKEYPLKMDYTEEGIKPQQVIEELSRVTKDEAIVTTDVGQHQMWAA 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 402 QFLHVQQARHWINCGQAGPLGWTVPAALGVRVADPEAPVVAISGDYDFQFMLEELAVGAQFNLPYVHVVVNNSYLGLIRQ 481
Cdd:TIGR00118 395 QFYPFRKPRRFITSGGLGTMGFGLPAAIGAKVAKPESTVICITGDGSFQMNLQELSTAVQYDIPVKILILNNRYLGMVRQ 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 482 AQRGFdmdYCVQLSFENINApelgayGVDHVKVAEGLGCKAIRVHEPGDLLPAFEKagnlAAEHQVPVVVEVILERVTNI 561
Cdd:TIGR00118 475 WQELF---YEERYSHTHMGS------LPDFVKLAEAYGIKGIRIEKPEELDEKLKE----ALSSNEPVLLDVVVDKPENV 541
|
|
| TPP_Gcl |
cd02006 |
Thiamine pyrophosphate (TPP) family, Gcl subfamily, TPP-binding module; composed of proteins ... |
363-564 |
1.72e-138 |
|
Thiamine pyrophosphate (TPP) family, Gcl subfamily, TPP-binding module; composed of proteins similar to Escherichia coli glyoxylate carboligase (Gcl). E. coli glyoxylate carboligase, plays a key role in glyoxylate metabolism where it catalyzes the condensation of two molecules of glyoxylate to give tartronic semialdehyde and carbon dioxide. This enzyme requires TPP, magnesium ion and FAD as cofactors.
Pssm-ID: 238964 [Multi-domain] Cd Length: 202 Bit Score: 400.50 E-value: 1.72e-138
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 363 THFDDVPIKPQRVYEEMNRAFGPETRYVSAIGLSQIAAAQFLHVQQARHWINCGQAGPLGWTVPAALGVRVADPEAPVVA 442
Cdd:cd02006 1 THFDDVPIKPQRVYEEMNKAFGRDVRYVTTIGLSQIAGAQMLHVYKPRHWINCGQAGPLGWTVPAALGVAAADPDRQVVA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 443 ISGDYDFQFMLEELAVGAQFNLPYVHVVVNNSYLGLIRQAQRGFDMDYCVQLSFENINAPELGAYGVDHVKVAEGLGCKA 522
Cdd:cd02006 81 LSGDYDFQFMIEELAVGAQHRIPYIHVLVNNAYLGLIRQAQRAFDMDYQVNLAFENINSSELGGYGVDHVKVAEGLGCKA 160
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 497628394 523 IRVHEPGDLLPAFEKAGNLAAEHQVPVVVEVILERVTNISMG 564
Cdd:cd02006 161 IRVTKPEELAAAFEQAKKLMAEHRVPVVVEAILERVTNISMG 202
|
|
| PRK06048 |
PRK06048 |
acetolactate synthase large subunit; |
1-562 |
1.08e-136 |
|
acetolactate synthase large subunit;
Pssm-ID: 180368 [Multi-domain] Cd Length: 561 Bit Score: 409.55 E-value: 1.08e-136
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 1 MPKMTAAAAAVEILKREGVDHAFGVPGAAINPFYAALRaRGGIGHTLARHVEGASHMAEGYTRtAPGNIGVCVGTSGPAG 80
Cdd:PRK06048 5 TEKMTGARAIIKCLEKEGVEVIFGYPGGAIIPVYDELY-DSDLRHILVRHEQAAAHAADGYAR-ATGKVGVCVATSGPGA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 81 TDMITGLYSASADSVPILCITGQAPVARLHKEDFQAVDISSIAQPVTKMAVTVLEPAQVPGAFQRAFHLMRSGRPGPVLI 160
Cdd:PRK06048 83 TNLVTGIATAYMDSVPIVALTGQVPRSMIGNDAFQEADITGITMPITKHNYLVQDAKDLPRIIKEAFHIASTGRPGPVLI 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 161 DLPVDVQLAEIEFD-PDTYEpMPLARP--AATRAQAEKALAMLAAAERPLIVAGGGIVNADAAGLLVEFAELVDVPVVPT 237
Cdd:PRK06048 163 DLPKDVTTAEIDFDyPDKVE-LRGYKPtyKGNPQQIKRAAELIMKAERPIIYAGGGVISSNASEELVELAETIPAPVTTT 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 238 LMGWGTIADDHPLMAGMVGLQAAhRYGNATMLEADFVLGIGNRWANRHTGGLDTYTRGRTFVHVDIEPTQIGRVFAPGYG 317
Cdd:PRK06048 242 LMGIGAIPTEHPLSLGMLGMHGT-KYANYAIQESDLIIAVGARFDDRVTGKLASFAPNAKIIHIDIDPAEISKNVKVDVP 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 318 IVSDAGAALERFVEVARARkaagtlpDRSEWVAQCRRRKQTLQRRTHFDDVPIKPQRVYEEMNRAFgPETRYVSAIGLSQ 397
Cdd:PRK06048 321 IVGDAKQVLKSLIKYVQYC-------DRKEWLDKINQWKKEYPLKYKEREDVIKPQYVIEQIYELC-PDAIIVTEVGQHQ 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 398 IAAAQFLHVQQARHWINCGQAGPLGWTVPAALGVRVADPEAPVVAISGDYDFQFMLEELAVGAQFNLPYVHVVVNNSYLG 477
Cdd:PRK06048 393 MWAAQYFKYKYPRTFITSGGLGTMGYGFPAAIGAKVGKPDKTVIDIAGDGSFQMNSQELATAVQNDIPVIVAILNNGYLG 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 478 LIRQAQrgfdmdycvQLSFENINAPELGAYGVDHVKVAEGLGCKAIRVHEPGDLLPAFEKAGNLAAehqvPVVVEVILER 557
Cdd:PRK06048 473 MVRQWQ---------ELFYDKRYSHTCIKGSVDFVKLAEAYGALGLRVEKPSEVRPAIEEAVASDR----PVVIDFIVEC 539
|
....*
gi 497628394 558 VTNIS 562
Cdd:PRK06048 540 EENVS 544
|
|
| PRK07789 |
PRK07789 |
acetolactate synthase 1 catalytic subunit; Validated |
3-554 |
2.66e-128 |
|
acetolactate synthase 1 catalytic subunit; Validated
Pssm-ID: 236098 [Multi-domain] Cd Length: 612 Bit Score: 389.73 E-value: 2.66e-128
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 3 KMTAAAAAVEILKREGVDHAFGVPGAAINPFYAALRARGGIGHTLARHVEGASHMAEGYTRtAPGNIGVCVGTSGPAGTD 82
Cdd:PRK07789 30 RMTGAQAVVRSLEELGVDVVFGIPGGAILPVYDPLFDSTKVRHVLVRHEQGAGHAAEGYAQ-ATGRVGVCMATSGPGATN 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 83 MITGLYSASADSVPILCITGQAPVARLHKEDFQAVDISSIAQPVTKMAVTVLEPAQVPGAFQRAFHLMRSGRPGPVLIDL 162
Cdd:PRK07789 109 LVTPIADANMDSVPVVAITGQVGRGLIGTDAFQEADIVGITMPITKHNFLVTDADDIPRVIAEAFHIASTGRPGPVLVDI 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 163 PVDVQLAEIEFD-PDTYEpMPLARPaATRA---QAEKALAMLAAAERPLIVAGGGIVNADAAGLLVEFAELVDVPVVPTL 238
Cdd:PRK07789 189 PKDALQAQTTFSwPPRMD-LPGYRP-VTKPhgkQIREAAKLIAAARRPVLYVGGGVIRAEASAELRELAELTGIPVVTTL 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 239 MGWGTIADDHPL---MAGMVGLQAAhrygNATMLEADFVLGIGNRWANRHTGGLDTYTRGRTFVHVDIEPTQIGRVFAPG 315
Cdd:PRK07789 267 MARGAFPDSHPQhlgMPGMHGTVAA----VAALQRSDLLIALGARFDDRVTGKLDSFAPDAKVIHADIDPAEIGKNRHAD 342
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 316 YGIVSDAGAALERFVEVARARKAAGTLPDRSEWVAQCRRRKQTLQRR-THFDDVPIKPQRVYEEMNRAFGPETRYVSAIG 394
Cdd:PRK07789 343 VPIVGDVKEVIAELIAALRAEHAAGGKPDLTAWWAYLDGWRETYPLGyDEPSDGSLAPQYVIERLGEIAGPDAIYVAGVG 422
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 395 LSQIAAAQFLHVQQARHWINCGQAGPLGWTVPAALGVRVADPEAPVVAISGDYDFQFMLEELAVGAQFNLPYVHVVVNNS 474
Cdd:PRK07789 423 QHQMWAAQFIDYEKPRTWLNSGGLGTMGYAVPAAMGAKVGRPDKEVWAIDGDGCFQMTNQELATCAIEGIPIKVALINNG 502
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 475 YLGLIRQAQRGFdmdYCVQLSfeNINAPELGAYGVDHVKVAEGLGCKAIRVHEPGDLLPAFEKAgnlAAEHQVPVVVEVI 554
Cdd:PRK07789 503 NLGMVRQWQTLF---YEERYS--NTDLHTHSHRIPDFVKLAEAYGCVGLRCEREEDVDAVIEKA---RAINDRPVVIDFV 574
|
|
| PRK06276 |
PRK06276 |
acetolactate synthase large subunit; |
4-563 |
5.30e-128 |
|
acetolactate synthase large subunit;
Pssm-ID: 235766 [Multi-domain] Cd Length: 586 Bit Score: 387.96 E-value: 5.30e-128
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 4 MTAAAAAVEILKREGVDHAFGVPGAAINPFYAALRaRGGIGHTLARHVEGASHMAEGYTRtAPGNIGVCVGTSGPAGTDM 83
Cdd:PRK06276 1 MKGAEAIIKALEAEGVKIIFGYPGGALLPFYDALY-DSDLIHILTRHEQAAAHAADGYAR-ASGKVGVCVATSGPGATNL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 84 ITGLYSASADSVPILCITGQAPVARLHKEDFQAVDISSIAQPVTKMAVTVLEPAQVPGAFQRAFHLMRSGRPGPVLIDLP 163
Cdd:PRK06276 79 VTGIATAYADSSPVIALTGQVPTKLIGNDAFQEIDALGIFMPITKHNFQIKKPEEIPEIFRAAFEIAKTGRPGPVHIDLP 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 164 VDVQLAEIEFD----PDT-----YEPMPLARPaatrAQAEKALAMLAAAERPLIVAGGGIVNADAAGLLVEFAELVDVPV 234
Cdd:PRK06276 159 KDVQEGELDLEkypiPAKidlpgYKPTTFGHP----LQIKKAAELIAEAERPVILAGGGVIISGASEELIELSELVKIPV 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 235 VPTLMGWGTIADDHPL---MAGMVGLQAAhrygNATMLEADFVLGIGNRWANRHTGGLDTYTRGRTFVHVDIEPTQIGRV 311
Cdd:PRK06276 235 CTTLMGKGAFPEDHPLalgMVGMHGTKAA----NYSVTESDVLIAIGCRFSDRTTGDISSFAPNAKIIHIDIDPAEIGKN 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 312 FAPGYGIVSDAGAALERFVEVARARKaagtLPDRSEWVAQCRRRKQTLQRRTHFDDVPIKPQRVYEEMNRAFGP-----E 386
Cdd:PRK06276 311 VRVDVPIVGDAKNVLRDLLAELMKKE----IKNKSEWLERVKKLKKESIPRMDFDDKPIKPQRVIKELMEVLREidpskN 386
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 387 TRYVSAIGLSQIAAAQFLHVQQARHWINCGQAGPLGWTVPAALGVRVADPEAPVVAISGDYDFQFMLEELAVGAQFNLPY 466
Cdd:PRK06276 387 TIITTDVGQNQMWMAHFFKTSAPRSFISSGGLGTMGFGFPAAIGAKVAKPDANVIAITGDGGFLMNSQELATIAEYDIPV 466
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 467 VHVVVNNSYLGLIRQAQRGF-DMDYC-VQLSfeniNAPelgaygvDHVKVAEGLGCKAIRVHEPGDLLPAFEKagnlAAE 544
Cdd:PRK06276 467 VICIFDNRTLGMVYQWQNLYyGKRQSeVHLG----ETP-------DFVKLAESYGVKADRVEKPDEIKEALKE----AIK 531
|
570
....*....|....*....
gi 497628394 545 HQVPVVVEVILERVTNISM 563
Cdd:PRK06276 532 SGEPYLLDIIIDPAEALPM 550
|
|
| PRK07418 |
PRK07418 |
acetolactate synthase large subunit; |
3-560 |
3.43e-125 |
|
acetolactate synthase large subunit;
Pssm-ID: 236014 [Multi-domain] Cd Length: 616 Bit Score: 381.71 E-value: 3.43e-125
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 3 KMTAAAAAVEILKREGVDHAFGVPGAAINPFYAAL---RARGGIGHTLARHVEGASHMAEGYTRtAPGNIGVCVGTSGPA 79
Cdd:PRK07418 18 RATGAYALMDSLKRHGVKHIFGYPGGAILPIYDELykaEAEGWLKHILVRHEQGAAHAADGYAR-ATGKVGVCFGTSGPG 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 80 GTDMITGLYSASADSVPILCITGQAPVARLHKEDFQAVDISSIAQPVTKMAVTVLEPAQVPGAFQRAFHLMRSGRPGPVL 159
Cdd:PRK07418 97 ATNLVTGIATAQMDSVPMVVITGQVPRPAIGTDAFQETDIFGITLPIVKHSYVVRDPSDMARIVAEAFHIASSGRPGPVL 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 160 IDLPVDVQLAEIEFDPdtYEPMPLARPAATR------AQAEKALAMLAAAERPLIVAGGGIVNADAAGLLVEFAELVDVP 233
Cdd:PRK07418 177 IDIPKDVGQEEFDYVP--VEPGSVKPPGYRPtvkgnpRQINAALKLIEEAERPLLYVGGGAISAGAHAELKELAERFQIP 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 234 VVPTLMGWGTIADDHPLMAGMVGLQAAhRYGNATMLEADFVLGIGNRWANRHTGGLDTYTRGRTFVHVDIEPTQIGRVFA 313
Cdd:PRK07418 255 VTTTLMGKGAFDEHHPLSVGMLGMHGT-AYANFAVTECDLLIAVGARFDDRVTGKLDEFASRAKVIHIDIDPAEVGKNRR 333
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 314 PGYGIVSDAGAALERFVEVARARKAAgtlPDRSEWVAQCRRRKQTLQRRTHFDDVPIKPQRVYEEMNRaFGPETRYVSAI 393
Cdd:PRK07418 334 PDVPIVGDVRKVLVKLLERSLEPTTP---PRTQAWLERINRWKQDYPLVVPPYEGEIYPQEVLLAVRD-LAPDAYYTTDV 409
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 394 GLSQIAAAQFLHvQQARHWINCGQAGPLGWTVPAALGVRVADPEAPVVAISGDYDFQFMLEELAVGAQFNLPYVHVVVNN 473
Cdd:PRK07418 410 GQHQMWAAQFLR-NGPRRWISSAGLGTMGFGMPAAMGVKVALPDEEVICIAGDASFLMNIQELGTLAQYGINVKTVIINN 488
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 474 SYLGLIRQAQRGFdmdYCVQLSFENINAPElgaygVDHVKVAEGLGCKAIRVHEPGDLLPAFEKAgnLAaeHQVPVVVEV 553
Cdd:PRK07418 489 GWQGMVRQWQESF---YGERYSASNMEPGM-----PDFVKLAEAFGVKGMVISERDQLKDAIAEA--LA--HDGPVLIDV 556
|
....*..
gi 497628394 554 ILERVTN 560
Cdd:PRK07418 557 HVRRDEN 563
|
|
| PRK08527 |
PRK08527 |
acetolactate synthase large subunit; |
3-561 |
3.48e-118 |
|
acetolactate synthase large subunit;
Pssm-ID: 181458 [Multi-domain] Cd Length: 563 Bit Score: 361.72 E-value: 3.48e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 3 KMTAAAAAVEILKREGVDHAFGVPGAAINPFYAALRARGGIGHTLARHVEGASHMAEGYTRtAPGNIGVCVGTSGPAGTD 82
Cdd:PRK08527 2 KLSGSQMVCEALKEEGVKVVFGYPGGAILNIYDEIYKQNYFKHILTRHEQAAVHAADGYAR-ASGKVGVAIVTSGPGFTN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 83 MITGLYSASADSVPILCITGQAPVARLHKEDFQAVDISSIAQPVTKMAVTVLEPAQVPGAFQRAFHLMRSGRPGPVLIDL 162
Cdd:PRK08527 81 AVTGLATAYMDSIPLVLISGQVPNSLIGTDAFQEIDAVGISRPCVKHNYLVKSIEELPRILKEAFYIARSGRPGPVHIDI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 163 PVDVQLAEIEFD-PD-----TYEPMPLARPAatraQAEKALAMLAAAERPLIVAGGGIVNADAAGLLVEFAELVDVPVVP 236
Cdd:PRK08527 161 PKDVTATLGEFEyPKeislkTYKPTYKGNSR----QIKKAAEAIKEAKKPLFYLGGGAILSNASEEIRELVKKTGIPAVE 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 237 TLMGWGTIADDHPLMAGMVGLQAAHRyGNATMLEADFVLGIGNRWANRHTGGLDTYTRGRTFVHVDIEPTQIGRVFAPGY 316
Cdd:PRK08527 237 TLMARGVLRSDDPLLLGMLGMHGSYA-ANMAMSECDLLISLGARFDDRVTGKLSEFAKHAKIIHVDIDPSSISKIVNADY 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 317 GIVSDAGAALERFVEvararKAAGTLPDR-SEWVAQCRRRKQTLQRRTHFDDVPIKPQRVYEEMNRAFGPETRYVSAIGL 395
Cdd:PRK08527 316 PIVGDLKNVLKEMLE-----ELKEENPTTyKEWREILKRYNELHPLSYEDSDEVLKPQWVIERVGELLGDDAIISTDVGQ 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 396 SQIAAAQFLHVQQARHWINCGQAGPLGWTVPAALGVRVADPEAPVVAISGDYDFQFMLEELAVGAQFNLPYVHVVVNNSY 475
Cdd:PRK08527 391 HQMWVAQFYPFNYPRQLATSGGLGTMGYGLPAALGAKLAVPDKVVINFTGDGSILMNIQELMTAVEYKIPVINIILNNNF 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 476 LGLIRQAQRGFdmdYCVQLSFENINA-PelgaygvDHVKVAEGLGCKAIRVHEPGDllpaFEKAGNLAAEHQVPVVVEVI 554
Cdd:PRK08527 471 LGMVRQWQTFF---YEERYSETDLSTqP-------DFVKLAESFGGIGFRVTTKEE----FDKALKEALESDKVALIDVK 536
|
....*..
gi 497628394 555 LERVTNI 561
Cdd:PRK08527 537 IDRFENV 543
|
|
| PRK09107 |
PRK09107 |
acetolactate synthase 3 catalytic subunit; Validated |
3-531 |
2.21e-117 |
|
acetolactate synthase 3 catalytic subunit; Validated
Pssm-ID: 236380 [Multi-domain] Cd Length: 595 Bit Score: 360.95 E-value: 2.21e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 3 KMTAAAAAVEILKREGVDHAFGVPGAAINPFYAALRARGGIGHTLARHVEGASHMAEGYTRTApGNIGVCVGTSGPAGTD 82
Cdd:PRK09107 10 QMTGAEMVVQALKDQGVEHIFGYPGGAVLPIYDEIFQQDDIQHILVRHEQGAGHAAEGYARST-GKPGVVLVTSGPGATN 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 83 MITGLYSASADSVPILCITGQAPVARLHKEDFQAVDISSIAQPVTKMAVTVLEPAQVPGAFQRAFHLMRSGRPGPVLIDL 162
Cdd:PRK09107 89 AVTPLQDALMDSIPLVCITGQVPTHLIGSDAFQECDTVGITRPCTKHNWLVKDVNDLARVIHEAFHVATSGRPGPVVVDI 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 163 PVDVQLAEIEFDP-------DTYEPmplaRPAATRAQAEKALAMLAAAERPLIVAGGGIVNA--DAAGLLVEFAELVDVP 233
Cdd:PRK09107 169 PKDVQFATGTYTPpqkapvhVSYQP----KVKGDAEAITEAVELLANAKRPVIYSGGGVINSgpEASRLLRELVELTGFP 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 234 VVPTLMGWGTIADDHPLMAGMVGLQAAHRyGNATMLEADFVLGIGNRWANRHTGGLDTYTRGRTFVHVDIEPTQIGRVFA 313
Cdd:PRK09107 245 ITSTLMGLGAYPASGKNWLGMLGMHGTYE-ANMAMHDCDVMLCVGARFDDRITGRLDAFSPNSKKIHIDIDPSSINKNVR 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 314 PGYGIVSDAGAALERFVEVARARKAAGTLPDRSEWVAQ--CRRRKQTLQRRTHfDDVpIKPQRVYEEMNRAFGPETRYVS 391
Cdd:PRK09107 324 VDVPIIGDVGHVLEDMLRLWKARGKKPDKEALADWWGQiaRWRARNSLAYTPS-DDV-IMPQYAIQRLYELTKGRDTYIT 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 392 A-IGLSQIAAAQFLHVQQARHWINCGQAGPLGWTVPAALGVRVADPEAPVVAISGDYDFQFMLEELAVGAQFNLPYVHVV 470
Cdd:PRK09107 402 TeVGQHQMWAAQFFGFEEPNRWMTSGGLGTMGYGLPAALGVQIAHPDALVIDIAGDASIQMCIQEMSTAVQYNLPVKIFI 481
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 497628394 471 VNNSYLGLIRQAQrgfdmdycvQLSFENINAPELGAYGVDHVKVAEGLGCKAIRVHEPGDL 531
Cdd:PRK09107 482 LNNQYMGMVRQWQ---------QLLHGNRLSHSYTEAMPDFVKLAEAYGAVGIRCEKPGDL 533
|
|
| PRK07282 |
PRK07282 |
acetolactate synthase large subunit; |
11-513 |
2.66e-117 |
|
acetolactate synthase large subunit;
Pssm-ID: 180919 [Multi-domain] Cd Length: 566 Bit Score: 359.91 E-value: 2.66e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 11 VEILKREGVDHAFGVPGAAINPFYAALRARGGIGHTLARHVEGASHMAEGYTRTApGNIGVCVGTSGPAGTDMITGLYSA 90
Cdd:PRK07282 17 LETLRDLGVDTIFGYPGGAVLPLYDAIYNFEGIRHILARHEQGALHEAEGYAKST-GKLGVAVVTSGPGATNAITGIADA 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 91 SADSVPILCITGQAPVARLHKEDFQAVDISSIAQPVTKMAVTVLEPAQVPGAFQRAFHLMRSGRPGPVLIDLPVDVQLAE 170
Cdd:PRK07282 96 MSDSVPLLVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQIRETADIPRIITEAVHIATTGRPGPVVIDLPKDVSALE 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 171 IEFDPDTYEPMPLARPA--ATRAQAEKALAMLAAAERPLIVAGGGIVNADAAGLLVEFAELVDVPVVPTLMGWGTIADDH 248
Cdd:PRK07282 176 TDFIYDPEVNLPSYQPTlePNDMQIKKILKQLSKAKKPVILAGGGINYAEAATELNAFAERYQIPVVTTLLGQGTIATSH 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 249 PL---MAGMVGLQAAhrygNATMLEADFVLGIGNRWANRHTGGLDTYTRGRTFVHVDIEPTQIGRVFAPGYGIVSDAGAA 325
Cdd:PRK07282 256 PLflgMGGMHGSYAA----NIAMTEADFMINIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIIKTDIPVVGDAKKA 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 326 LERFVEVARARKaagtlpDRSEWVAQCRRRKQTLqRRTHFDDVPIKPQRVYEEMNRAFGPETRYVSAIGLSQIAAAQFLH 405
Cdd:PRK07282 332 LQMLLAEPTVHN------NTEKWIEKVTKDKNRV-RSYDKKERVVQPQAVIERIGELTNGDAIVVTDVGQHQMWAAQYYP 404
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 406 VQQARHWINCGQAGPLGWTVPAALGVRVADPEAPVVAISGDYDFQFMLEELAVGAQFNLPYVHVVVNNSYLGLIRQAQRG 485
Cdd:PRK07282 405 YQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVILFVGDGGFQMTNQELAILNIYKVPIKVVMLNNHSLGMVRQWQES 484
|
490 500 510
....*....|....*....|....*....|
gi 497628394 486 FDMDYCVQLSFENINAPEL--GAYGVDHVK 513
Cdd:PRK07282 485 FYEGRTSESVFDTLPDFQLmaQAYGIKHYK 514
|
|
| ilvB |
CHL00099 |
acetohydroxyacid synthase large subunit |
3-560 |
9.09e-116 |
|
acetohydroxyacid synthase large subunit
Pssm-ID: 214363 [Multi-domain] Cd Length: 585 Bit Score: 356.32 E-value: 9.09e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 3 KMTAAAAAVEILKREGVDHAFGVPGAAINPFYAALRA---RGGIGHTLARHVEGASHMAEGYTRTApGNIGVCVGTSGPA 79
Cdd:CHL00099 9 EKTGAFALIDSLVRHGVKHIFGYPGGAILPIYDELYAwekKGLIKHILVRHEQGAAHAADGYARST-GKVGVCFATSGPG 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 80 GTDMITGLYSASADSVPILCITGQAPVARLHKEDFQAVDISSIAQPVTKMAVTVLEPAQVPGAFQRAFHLMRSGRPGPVL 159
Cdd:CHL00099 88 ATNLVTGIATAQMDSVPLLVITGQVGRAFIGTDAFQEVDIFGITLPIVKHSYVVRDARDISRIVAEAFYIAKHGRPGPVL 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 160 IDLPVDVQLAEIEFDP----DTYEPMPLARPA--ATRAQAEKALAMLAAAERPLIVAGGGIVNADAAGLLVEFAELVDVP 233
Cdd:CHL00099 168 IDIPKDVGLEKFDYYPpepgNTIIKILGCRPIykPTIKRIEQAAKLILQSSQPLLYVGGGAIISDAHQEITELAELYKIP 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 234 VVPTLMGWGTIADDHPLMAGMVGLQAAhRYGNATMLEADFVLGIGNRWANRHTGGLDTYTRGRTFVHVDIEPTQIGRVFA 313
Cdd:CHL00099 248 VTTTLMGKGIFDEDHPLCLGMLGMHGT-AYANFAVSECDLLIALGARFDDRVTGKLDEFACNAQVIHIDIDPAEIGKNRI 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 314 PGYGIVSDAGAALERFVEVArarKAAGTLPDRSE---WVAQCRRRKQTLQRRTHFDDVPIKPQRVYEEMNRaFGPETRYV 390
Cdd:CHL00099 327 PQVAIVGDVKKVLQELLELL---KNSPNLLESEQtqaWRERINRWRKEYPLLIPKPSTSLSPQEVINEISQ-LAPDAYFT 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 391 SAIGLSQIAAAQFLHVQQaRHWINCGQAGPLGWTVPAALGVRVADPEAPVVAISGDYDFQFMLEELAVGAQFNLPYVHVV 470
Cdd:CHL00099 403 TDVGQHQMWAAQFLKCKP-RKWLSSAGLGTMGYGLPAAIGAQIAHPNELVICISGDASFQMNLQELGTIAQYNLPIKIII 481
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 471 VNNSYLGLIRQAQRGFdmdYCVQLSFENIN--APelgaygvDHVKVAEGLGCKAIRVHEPGDLLPAFEKagnlAAEHQVP 548
Cdd:CHL00099 482 INNKWQGMVRQWQQAF---YGERYSHSNMEegAP-------DFVKLAEAYGIKGLRIKSRKDLKSSLKE----ALDYDGP 547
|
570
....*....|..
gi 497628394 549 VVVEVILERVTN 560
Cdd:CHL00099 548 VLIDCQVIEDEN 559
|
|
| PRK06725 |
PRK06725 |
acetolactate synthase large subunit; |
4-561 |
8.09e-111 |
|
acetolactate synthase large subunit;
Pssm-ID: 180672 [Multi-domain] Cd Length: 570 Bit Score: 343.10 E-value: 8.09e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 4 MTAAAAAVEILKREGVDHAFGVPGAAINPFYAALRArGGIGHTLARHVEGASHMAEGYTRtAPGNIGVCVGTSGPAGTDM 83
Cdd:PRK06725 15 VTGAGHVIQCLKKLGVTTVFGYPGGAILPVYDALYE-SGLKHILTRHEQAAIHAAEGYAR-ASGKVGVVFATSGPGATNL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 84 ITGLYSASADSVPILCITGQAPVARLHKEDFQAVDISSIAQPVTKMAVTVLEPAQVPGAFQRAFHLMRSGRPGPVLIDLP 163
Cdd:PRK06725 93 VTGLADAYMDSIPLVVITGQVATPLIGKDGFQEADVVGITVPVTKHNYQVRDVNQLSRIVQEAFYIAESGRPGPVLIDIP 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 164 VDVQLAEIEF------DPDTYEPMPLARPAATRAQAEKalamLAAAERPLIVAGGGIVNADAAGLLVEFAELVDVPVVPT 237
Cdd:PRK06725 173 KDVQNEKVTSfynevvEIPGYKPEPRPDSMKLREVAKA----ISKAKRPLLYIGGGVIHSGGSEELIEFARENRIPVVST 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 238 LMGWGTIADDHPLMAGMVGLQAAHRyGNATMLEADFVLGIGNRWANRHTGGLDTYTRGRTFVHVDIEPTQIGRVFAPGYG 317
Cdd:PRK06725 249 LMGLGAYPPGDPLFLGMLGMHGTYA-ANMAVTECDLLLALGVRFDDRVTGKLELFSPHSKKVHIDIDPSEFHKNVAVEYP 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 318 IVSDAGAALERFVEVARARKAagtlpdrSEWVAQCRRRKQTLQRRTHFDDVPIKPQRVYEEMNRAFGPETRYVSAIGLSQ 397
Cdd:PRK06725 328 VVGDVKKALHMLLHMSIHTQT-------DEWLQKVKTWKEEYPLSYKQKESELKPQHVINLVSELTNGEAIVTTEVGQHQ 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 398 IAAAQFLHVQQARHWINCGQAGPLGWTVPAALGVRVADPEAPVVAISGDYDFQFMLEELAVGAQFNLPYVHVVVNNSYLG 477
Cdd:PRK06725 401 MWAAHFYKAKNPRTFLTSGGLGTMGFGFPAAIGAQLAKEEELVICIAGDASFQMNIQELQTIAENNIPVKVFIINNKFLG 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 478 LIRQAQRGFdmdYCVQLSFENINAPelgaygvDHVKVAEGLGCKAIRVHEPGDLLPAFEKagnlAAEHQVPVVVEVILER 557
Cdd:PRK06725 481 MVRQWQEMF---YENRLSESKIGSP-------DFVKVAEAYGVKGLRATNSTEAKQVMLE----AFAHEGPVVVDFCVEE 546
|
....
gi 497628394 558 VTNI 561
Cdd:PRK06725 547 GENV 550
|
|
| PRK07710 |
PRK07710 |
acetolactate synthase large subunit; |
3-553 |
2.96e-110 |
|
acetolactate synthase large subunit;
Pssm-ID: 236076 [Multi-domain] Cd Length: 571 Bit Score: 341.74 E-value: 2.96e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 3 KMTAAAAAVEILKREGVDHAFGVPGAAINPFYAALRaRGGIGHTLARHVEGASHMAEGYTRTApGNIGVCVGTSGPAGTD 82
Cdd:PRK07710 15 LMTGAQMLIEALEKEGVEVIFGYPGGAVLPLYDALY-DCGIPHILTRHEQGAIHAAEGYARIS-GKPGVVIATSGPGATN 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 83 MITGLYSASADSVPILCITGQAPVARLHKEDFQAVDISSIAQPVTKMAVTVLEPAQVPGAFQRAFHLMRSGRPGPVLIDL 162
Cdd:PRK07710 93 VVTGLADAMIDSLPLVVFTGQVATSVIGSDAFQEADIMGITMPVTKHNYQVRKASDLPRIIKEAFHIATTGRPGPVLIDI 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 163 PVDVQLAEIEFDPD----------TYEPMPLarpaatraQAEKALAMLAAAERPLIVAGGGIVNADAAGLLVEFAELVDV 232
Cdd:PRK07710 173 PKDMVVEEGEFCYDvqmdlpgyqpNYEPNLL--------QIRKLVQAVSVAKKPVILAGAGVLHAKASKELTSYAEQQEI 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 233 PVVPTLMGWGTIADDHPLMAGMVGLQAAHRyGNATMLEADFVLGIGNRWANRHTGGLDTYTRGRTFVHVDIEPTQIGRVF 312
Cdd:PRK07710 245 PVVHTLLGLGGFPADHPLFLGMAGMHGTYT-ANMALYECDLLINIGARFDDRVTGNLAYFAKEATVAHIDIDPAEIGKNV 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 313 APGYGIVSDAGAALERFVevararKAAGTLPDRSEWVAQCRRRKQTLQRRTHFDDVPIKPQRVYEEMNRAFGPETRYVSA 392
Cdd:PRK07710 324 PTEIPIVADAKQALQVLL------QQEGKKENHHEWLSLLKNWKEKYPLSYKRNSESIKPQKAIEMLYEITKGEAIVTTD 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 393 IGLSQIAAAQFLHVQQARHWINCGQAGPLGWTVPAALGVRVADPEAPVVAISGDYDFQFMLEELAVGAQFNLPYVHVVVN 472
Cdd:PRK07710 398 VGQHQMWAAQYYPFKTPDKWVTSGGLGTMGFGLPAAIGAQLAKPDETVVAIVGDGGFQMTLQELSVIKELSLPVKVVILN 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 473 NSYLGLIRQAQRGFdmdYCVQLSFENI-NAPelgaygvDHVKVAEGLGCKAIRVHEPGDLLPAFEKagnlAAEHQVPVVV 551
Cdd:PRK07710 478 NEALGMVRQWQEEF---YNQRYSHSLLsCQP-------DFVKLAEAYGIKGVRIDDELEAKEQLQH----AIELQEPVVI 543
|
..
gi 497628394 552 EV 553
Cdd:PRK07710 544 DC 545
|
|
| PRK06882 |
PRK06882 |
acetolactate synthase 3 large subunit; |
1-531 |
1.60e-108 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 168717 [Multi-domain] Cd Length: 574 Bit Score: 337.27 E-value: 1.60e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 1 MPKMTAAAAAVEILKREGVDHAFGVPGAAINPFYAALRARGGIGHTLARHVEGASHMAEGYTRTApGNIGVCVGTSGPAG 80
Cdd:PRK06882 1 MKKLSGAEMVVQSLRDEGVEYVFGYPGGSVLDIYDAIHTLGGIEHVLVRHEQAAVHMADGYARST-GKVGCVLVTSGPGA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 81 TDMITGLYSASADSVPILCITGQAPVARLHKEDFQAVDISSIAQPVTKMAVTVLEPAQVPGAFQRAFHLMRSGRPGPVLI 160
Cdd:PRK06882 80 TNAITGIATAYTDSVPLVILSGQVPSNLIGTDAFQECDMLGISRPVVKHSFIVKNAEDIPSTIKKAFYIASTGRPGPVVI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 161 DLPVDVQLAEIEFDPDTYEPMPLARPAAT----RAQAEKALAMLAAAERPLIVAGGGIVNADAAGLLVEFAELVDVPVVP 236
Cdd:PRK06882 160 DIPKDMVNPANKFTYEYPEEVSLRSYNPTvqghKGQIKKALKALLVAKKPVLFVGGGVITAECSEQLTQFAQKLNLPVTS 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 237 TLMGWGTIADDHPLMAGMVGLQAAHRYGNAtMLEADFVLGIGNRWANRHTGGLDTYTRGRTFVHVDIEPTQIGRVFAPGY 316
Cdd:PRK06882 240 SLMGLGAYPSTDKQFLGMLGMHGTYEANNA-MHESDLILGIGVRFDDRTTNNLAKYCPNAKVIHIDIDPTSISKNVPAYI 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 317 GIVSDAGAALERFVEVARARKAAGTLPDRSEWVAQCRRRKQTLQRRTHFDDVPIKPQRVYEEMNRAFGPETRYVSAIGLS 396
Cdd:PRK06882 319 PIVGSAKNVLEEFLSLLEEENLAKSQTDLTAWWQQINEWKAKKCLEFDRTSDVIKPQQVVEAIYRLTNGDAYVASDVGQH 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 397 QIAAAQFLHVQQARHWINCGQAGPLGWTVPAALGVRVADPEAPVVAISGDYDFQFMLEELAVGAQFNLPYVHVVVNNSYL 476
Cdd:PRK06882 399 QMFAALHYPFDKPRRWINSGGAGTMGFGLPAAIGVKFAHPEATVVCVTGDGSIQMNIQELSTAKQYDIPVVIVSLNNRFL 478
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*.
gi 497628394 477 GLIRQAQrgfDMDYCVQLSFENINA-PelgaygvDHVKVAEGLGCKAIRVHEPGDL 531
Cdd:PRK06882 479 GMVKQWQ---DLIYSGRHSQVYMNSlP-------DFAKLAEAYGHVGIQIDTPDEL 524
|
|
| PRK08155 |
PRK08155 |
acetolactate synthase large subunit; |
1-538 |
3.65e-108 |
|
acetolactate synthase large subunit;
Pssm-ID: 181257 [Multi-domain] Cd Length: 564 Bit Score: 335.91 E-value: 3.65e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 1 MPKMTAAAAAVEILKREGVDHAFGVPGAAINPFYAALRARGGIGHTLARHVEGASHMAEGYTRTApGNIGVCVGTSGPAG 80
Cdd:PRK08155 10 RKRFTGAELIVRLLERQGIRIVTGIPGGAILPLYDALSQSTQIRHILARHEQGAGFIAQGMARTT-GKPAVCMACSGPGA 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 81 TDMITGLYSASADSVPILCITGQAPVARLHKEDFQAVDISSIAQPVTKMAVTVLEPAQVPGAFQRAFHLMRSGRPGPVLI 160
Cdd:PRK08155 89 TNLVTAIADARLDSIPLVCITGQVPASMIGTDAFQEVDTYGISIPITKHNYLVRDIEELPQVISDAFRIAQSGRPGPVWI 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 161 DLPVDVQLAEIEFD--PDTYEPMPLarPAATRAQAEKALAMLAAAERPLIVAGGGIVNADAAGLLVEFAELVDVPVVPTL 238
Cdd:PRK08155 169 DIPKDVQTAVIELEalPAPAEKDAA--PAFDEESIRDAAAMINAAKRPVLYLGGGVINSGAPARARELAEKAQLPTTMTL 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 239 MGWGTIADDHPLMAGMVGLQAAhRYGNATMLEADFVLGIGNRWANRHTGGLDTYTRGRTFVHVDIEPTQIGRVFAPGYGI 318
Cdd:PRK08155 247 MALGMLPKAHPLSLGMLGMHGA-RSTNYILQEADLLIVLGARFDDRAIGKTEQFCPNAKIIHVDIDRAELGKIKQPHVAI 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 319 VSDAGAALERFVEVARARkaagtlpDRSEWvaqcRRRKQTLQRRTHFD----DVPIKPQRVYEEMNRAFGPETRYVSAIG 394
Cdd:PRK08155 326 QADVDDVLAQLLPLVEAQ-------PRAEW----HQLVADLQREFPCPipkaDDPLSHYGLINAVAACVDDNAIITTDVG 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 395 LSQIAAAQFLHVQQARHWINCGQAGPLGWTVPAALGVRVADPEAPVVAISGDYDFQFMLEELAVGAQFNLPYVHVVVNNS 474
Cdd:PRK08155 395 QHQMWTAQAYPLNRPRQWLTSGGLGTMGFGLPAAIGAALANPERKVLCFSGDGSLMMNIQEMATAAENQLDVKIILMNNE 474
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 475 YLGLIRQAQ------RGFDMDYcvqlsfeninapelgAYGVDHVKVAEGLGCKAIRVHEPGDLLPAFEKA 538
Cdd:PRK08155 475 ALGLVHQQQslfygqRVFAATY---------------PGKINFMQIAAGFGLETCDLNNEADPQAALQEA 529
|
|
| PRK08979 |
PRK08979 |
acetolactate synthase 3 large subunit; |
1-538 |
2.17e-103 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 181602 [Multi-domain] Cd Length: 572 Bit Score: 324.08 E-value: 2.17e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 1 MPKMTAAAAAVEILKREGVDHAFGVPGAAINPFYAALRARGGIGHTLARHVEGASHMAEGYTRtAPGNIGVCVGTSGPAG 80
Cdd:PRK08979 1 MEMLSGASMIVRSLIDEGVKHIFGYPGGSVLDIYDALHEKSGIEHILVRHEQAAVHMADGYAR-ATGKVGVVLVTSGPGA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 81 TDMITGLYSASADSVPILCITGQAPVARLHKEDFQAVDISSIAQPVTKMAVTVLEPAQVPGAFQRAFHLMRSGRPGPVLI 160
Cdd:PRK08979 80 TNTITGIATAYMDSIPMVVLSGQVPSNLIGNDAFQECDMIGISRPVVKHSFLVKDAEDIPEIIKKAFYIASTGRPGPVVI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 161 DLPVDVQLAEIEFD---PDTYEpMPLARPAAT--RAQAEKALAMLAAAERPLIVAGGGIVNADAAGLLVEFAELVDVPVV 235
Cdd:PRK08979 160 DLPKDCLNPAILHPyeyPESIK-MRSYNPTTSghKGQIKRGLQALLAAKKPVLYVGGGAIISGADKQILQLAEKLNLPVV 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 236 PTLMGWGTIADDHPLMAGMVGLQAAHRyGNATMLEADFVLGIGNRWANRHTGGLDTYTRGRTFVHVDIEPTQIGRVFAPG 315
Cdd:PRK08979 239 STLMGLGAFPGTHKNSLGMLGMHGRYE-ANMAMHNADLIFGIGVRFDDRTTNNLEKYCPNATILHIDIDPSSISKTVRVD 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 316 YGIVSDAGAALERFVEVARARKAAGTLPDRSEW---VAQCRRRKQTLQRRThfdDVPIKPQRVYEEMNRAFGPETRYVSA 392
Cdd:PRK08979 318 IPIVGSADKVLDSMLALLDESGETNDEAAIASWwneIEVWRSRNCLAYDKS---SERIKPQQVIETLYKLTNGDAYVASD 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 393 IGLSQIAAAQFLHVQQARHWINCGQAGPLGWTVPAALGVRVADPEAPVVAISGDYDFQFMLEELAVGAQFNLPYVHVVVN 472
Cdd:PRK08979 395 VGQHQMFAALYYPFDKPRRWINSGGLGTMGFGLPAAMGVKFAMPDETVVCVTGDGSIQMNIQELSTALQYDIPVKIINLN 474
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 497628394 473 NSYLGLIRQAQrgfDMDYCVQLSFENINA-PelgaygvDHVKVAEGLGCKAIRVHEPGDLLPAFEKA 538
Cdd:PRK08979 475 NRFLGMVKQWQ---DMIYQGRHSHSYMDSvP-------DFAKIAEAYGHVGIRISDPDELESGLEKA 531
|
|
| PRK07979 |
PRK07979 |
acetolactate synthase 3 large subunit; |
1-538 |
2.37e-102 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 181185 [Multi-domain] Cd Length: 574 Bit Score: 321.41 E-value: 2.37e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 1 MPKMTAAAAAVEILKREGVDHAFGVPGAAINPFYAALRARGGIGHTLARHVEGASHMAEGYTRtAPGNIGVCVGTSGPAG 80
Cdd:PRK07979 1 MEMLSGAEMVVRSLIDQGVKQVFGYPGGAVLDIYDALHTVGGIDHVLVRHEQAAVHMADGLAR-ATGEVGVVLVTSGPGA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 81 TDMITGLYSASADSVPILCITGQAPVARLHKEDFQAVDISSIAQPVTKMAVTVLEPAQVPGAFQRAFHLMRSGRPGPVLI 160
Cdd:PRK07979 80 TNAITGIATAYMDSIPLVVLSGQVATSLIGYDAFQECDMVGISRPVVKHSFLVKQTEDIPQVLKKAFWLAASGRPGPVVV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 161 DLPVDVQLAEIEFD---PDTYEpMPLARPAAT--RAQAEKALAMLAAAERPLIVAGGGIVNADAAGLLVEFAELVDVPVV 235
Cdd:PRK07979 160 DLPKDILNPANKLPyvwPESVS-MRSYNPTTQghKGQIKRALQTLVAAKKPVVYVGGGAINAACHQQLKELVEKLNLPVV 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 236 PTLMGWGTIADDHPLMAGMVGLQAAHRyGNATMLEADFVLGIGNRWANRHTGGLDTYTRGRTFVHVDIEPTQIGRVFAPG 315
Cdd:PRK07979 239 SSLMGLGAFPATHRQSLGMLGMHGTYE-ANMTMHNADVIFAVGVRFDDRTTNNLAKYCPNATVLHIDIDPTSISKTVTAD 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 316 YGIVSDAGAALERFVEVARARKAAGTLPDRSEWVAQCR--RRKQTLQRRTHFDDvpIKPQRVYEEMNRAFGPETRYVSAI 393
Cdd:PRK07979 318 IPIVGDARQVLEQMLELLSQESAHQPLDEIRDWWQQIEqwRARQCLKYDTHSEK--IKPQAVIETLWRLTKGDAYVTSDV 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 394 GLSQIAAAQFLHVQQARHWINCGQAGPLGWTVPAALGVRVADPEAPVVAISGDYDFQFMLEELAVGAQFNLPYVHVVVNN 473
Cdd:PRK07979 396 GQHQMFAALYYPFDKPRRWINSGGLGTMGFGLPAALGVKMALPEETVVCVTGDGSIQMNIQELSTALQYELPVLVLNLNN 475
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 497628394 474 SYLGLIRQAQrgfDMDYCVQLSFENINAPElgaygvDHVKVAEGLGCKAIRVHEPGDLLPAFEKA 538
Cdd:PRK07979 476 RYLGMVKQWQ---DMIYSGRHSQSYMQSLP------DFVRLAEAYGHVGIQISHPDELESKLSEA 531
|
|
| PRK08978 |
PRK08978 |
acetolactate synthase 2 catalytic subunit; Reviewed |
4-486 |
3.30e-100 |
|
acetolactate synthase 2 catalytic subunit; Reviewed
Pssm-ID: 181601 [Multi-domain] Cd Length: 548 Bit Score: 314.90 E-value: 3.30e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 4 MTAAAAAVEILKREGVDHAFGVPGAAINPFYAALRArGGIGHTLARHVEGASHMAEGYTRtAPGNIGVCVGTSGPAGTDM 83
Cdd:PRK08978 1 MNGAQWVVHALRAQGVDTVFGYPGGAIMPVYDALYD-GGVEHLLCRHEQGAAMAAIGYAR-ATGKVGVCIATSGPGATNL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 84 ITGLYSASADSVPILCITGQAPVARLHKEDFQAVDISSIAQPVTKMAVTVLEPAQVPGAFQRAFHLMRSGRPGPVLIDLP 163
Cdd:PRK08978 79 ITGLADALLDSVPVVAITGQVSSPLIGTDAFQEIDVLGLSLACTKHSFLVQSLEELPEIMAEAFEIASSGRPGPVLVDIP 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 164 VDVQLAEIEFDPDTYEPMPlaRPAATRAQAEKALAMLAAAERPLIVAGGGIVNADAAGLLVEFAELVDVPVVPTLMGWGT 243
Cdd:PRK08978 159 KDIQLAEGELEPHLTTVEN--EPAFPAAELEQARALLAQAKKPVLYVGGGVGMAGAVPALREFLAATGMPAVATLKGLGA 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 244 IADDHPL---MAGMVGLQAAhrygNATMLEADFVLGIGNRWANRHTGGLDTYTRGRTFVHVDIEPTQIGRVFAPGYGIVS 320
Cdd:PRK08978 237 VEADHPYylgMLGMHGTKAA----NLAVQECDLLIAVGARFDDRVTGKLNTFAPHAKVIHLDIDPAEINKLRQAHVALQG 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 321 DAGAALErfvevararkAAGTLPDRSEWVAQCRRRKQTLQRRTHFDDVPIKPQRVYEEMNRAFGPETRYVSAIGLSQIAA 400
Cdd:PRK08978 313 DLNALLP----------ALQQPLNIDAWRQHCAQLRAEHAWRYDHPGEAIYAPALLKQLSDRKPADTVVTTDVGQHQMWV 382
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 401 AQFLHVQQARHWINCGQAGPLGWTVPAALGVRVADPEAPVVAISGDYDFQFMLEELAVGAQFNLPYVHVVVNNSYLGLIR 480
Cdd:PRK08978 383 AQHMRFTRPENFITSSGLGTMGFGLPAAIGAQVARPDDTVICVSGDGSFMMNVQELGTIKRKQLPVKIVLLDNQRLGMVR 462
|
....*.
gi 497628394 481 QAQRGF 486
Cdd:PRK08978 463 QWQQLF 468
|
|
| PRK06466 |
PRK06466 |
acetolactate synthase 3 large subunit; |
1-538 |
2.63e-99 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 180578 [Multi-domain] Cd Length: 574 Bit Score: 313.22 E-value: 2.63e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 1 MPKMTAAAAAVEILKREGVDHAFGVPGAAINPFYAALRARGGIGHTLARHVEGASHMAEGYTRtAPGNIGVCVGTSGPAG 80
Cdd:PRK06466 1 MELLSGAEMLVRALRDEGVEYIYGYPGGAVLHIYDALFKQDKVEHILVRHEQAATHMADGYAR-ATGKTGVVLVTSGPGA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 81 TDMITGLYSASADSVPILCITGQAPVARLHKEDFQAVDISSIAQPVTKMAVTVLEPAQVPGAFQRAFHLMRSGRPGPVLI 160
Cdd:PRK06466 80 TNAITGIATAYMDSIPMVVLSGQVPSTLIGEDAFQETDMVGISRPIVKHSFMVKHASEIPEIIKKAFYIAQSGRPGPVVV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 161 DLPVDVQLAEIEFD---PD-----TYEPmplarpaATR---AQAEKALAMLAAAERPLIVAGGGIVNADAAGLLVEFAEL 229
Cdd:PRK06466 160 DIPKDMTNPAEKFEyeyPKkvklrSYSP-------AVRghsGQIRKAVEMLLAAKRPVIYSGGGVVLGNASALLTELAHL 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 230 VDVPVVPTLMGWGTIADDHPLMAGMVGLQAAHRyGNATMLEADFVLGIGNRWANRHTGGLDTYTRGRTFVHVDIEPTQIG 309
Cdd:PRK06466 233 LNLPVTNTLMGLGGFPGTDRQFLGMLGMHGTYE-ANMAMHHADVILAVGARFDDRVTNGPAKFCPNAKIIHIDIDPASIS 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 310 RVFAPGYGIVSDAGAALERFVEVArarKAAGTLPDR---SEWVAQCR--RRKQTLQRRTHFDDVPIKPQRVYEEMNRAFG 384
Cdd:PRK06466 312 KTIKADIPIVGPVESVLTEMLAIL---KEIGEKPDKealAAWWKQIDewRGRHGLFPYDKGDGGIIKPQQVVETLYEVTN 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 385 PETRYVSAIGLSQIAAAQFLHVQQARHWINCGQAGPLGWTVPAALGVRVADPEAPVVAISGDYDFQFMLEELAVGAQFNL 464
Cdd:PRK06466 389 GDAYVTSDVGQHQMFAAQYYKFNKPNRWINSGGLGTMGFGLPAAMGVKLAFPDQDVACVTGEGSIQMNIQELSTCLQYGL 468
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 497628394 465 PYVHVVVNNSYLGLIRQAQrgfDMDYCVQLSFENINA-PelgaygvDHVKVAEGLGCKAIRVHEPGDLLPAFEKA 538
Cdd:PRK06466 469 PVKIINLNNGALGMVRQWQ---DMQYEGRHSHSYMESlP-------DFVKLAEAYGHVGIRITDLKDLKPKLEEA 533
|
|
| PRK06965 |
PRK06965 |
acetolactate synthase 3 catalytic subunit; Validated |
2-541 |
8.98e-95 |
|
acetolactate synthase 3 catalytic subunit; Validated
Pssm-ID: 180780 [Multi-domain] Cd Length: 587 Bit Score: 302.11 E-value: 8.98e-95
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 2 PKMTAAAAAVEILKREGVDHAFGVPGAAINPFYAALRARGGIGHTLARHVEGASHMAEGYTRtAPGNIGVCVGTSGPAGT 81
Cdd:PRK06965 19 ADSIGAEILMKALAAEGVEFIWGYPGGAVLYIYDELYKQDKIQHVLVRHEQAAVHAADGYAR-ATGKVGVALVTSGPGVT 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 82 DMITGLYSASADSVPILCITGQAPVARLHKEDFQAVDISSIAQPVTKMAVTVLEPAQVPGAFQRAFHLMRSGRPGPVLID 161
Cdd:PRK06965 98 NAVTGIATAYMDSIPMVVISGQVPTAAIGQDAFQECDTVGITRPIVKHNFLVKDVRDLAETVKKAFYIARTGRPGPVVVD 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 162 LPVDVQLAEIEFD-PDTYEpMPLARPA--ATRAQAEKALAMLAAAERPLIVAGGGIVNADAAGLLVEFAELVDVPVVPTL 238
Cdd:PRK06965 178 IPKDVSKTPCEYEyPKSVE-MRSYNPVtkGHSGQIRKAVSLLLSAKRPYIYTGGGVILANASRELRQLADLLGYPVTNTL 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 239 MGWGTIADDHPLMAGMVGLQAAHRYGNAtMLEADFVLGIGNRWANRHTGGLDTY-TRGRTFVHVDIEPTQIGRVFAPGYG 317
Cdd:PRK06965 257 MGLGAYPASDKKFLGMLGMHGTYEANMA-MQHCDVLIAIGARFDDRVIGNPAHFaSRPRKIIHIDIDPSSISKRVKVDIP 335
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 318 IVSDAGAALERFVEVARarkAAGTLPDR---SEWVAQCRR-RKQTLQRRTHFDDVpIKPQRVYEEMNRAFGPETRYVSAI 393
Cdd:PRK06965 336 IVGDVKEVLKELIEQLQ---TAEHGPDAdalAQWWKQIEGwRSRDCLKYDRESEI-IKPQYVVEKLWELTDGDAFVCSDV 411
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 394 GLSQIAAAQFLHVQQARHWINCGQAGPLGWTVPAALGVRVADPEAPVVAISGDYDFQFMLEELAVGAQFNLPYVHVVVNN 473
Cdd:PRK06965 412 GQHQMWAAQFYRFNEPRRWINSGGLGTMGVGLPYAMGIKMAHPDDDVVCITGEGSIQMCIQELSTCLQYDTPVKIISLNN 491
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 497628394 474 SYLGLIRQAQrgfDMDYCVQLSFENINA-PelgaygvDHVKVAEGLGCKAIRVHEPGDLLPAFEKAGNL 541
Cdd:PRK06965 492 RYLGMVRQWQ---EIEYSKRYSHSYMDAlP-------DFVKLAEAYGHVGMRIEKTSDVEPALREALRL 550
|
|
| PLN02470 |
PLN02470 |
acetolactate synthase |
11-554 |
6.22e-94 |
|
acetolactate synthase
Pssm-ID: 215261 [Multi-domain] Cd Length: 585 Bit Score: 299.73 E-value: 6.22e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 11 VEILKREGVDHAFGVPGAAINPFYAALRARGGIGHTLARHVEGASHMAEGYTRtAPGNIGVCVGTSGPAGTDMITGLYSA 90
Cdd:PLN02470 20 VEALEREGVDTVFAYPGGASMEIHQALTRSNCIRNVLCRHEQGEVFAAEGYAK-ASGKVGVCIATSGPGATNLVTGLADA 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 91 SADSVPILCITGQAPVARLHKEDFQAVDISSIAQPVTKMAVTVLEPAQVPGAFQRAFHLMRSGRPGPVLIDLPVDVQ--L 168
Cdd:PLN02470 99 LLDSVPLVAITGQVPRRMIGTDAFQETPIVEVTRSITKHNYLVMDVEDIPRVIREAFFLASSGRPGPVLVDIPKDIQqqL 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 169 AEIEFDPDTYEPMPLAR--PAATRAQAEKALAMLAAAERPLIVAGGGIVNADAAglLVEFAELVDVPVVPTLMGWGTIAD 246
Cdd:PLN02470 179 AVPNWNQPMKLPGYLSRlpKPPEKSQLEQIVRLISESKRPVVYVGGGCLNSSEE--LREFVELTGIPVASTLMGLGAFPA 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 247 DHPLMAGMVGLQAAhRYGNATMLEADFVLGIGNRWANRHTGGLDTYTRGRTFVHVDIEPTQIGRVFAPGYGIVSDAGAAL 326
Cdd:PLN02470 257 SDELSLQMLGMHGT-VYANYAVDSADLLLAFGVRFDDRVTGKLEAFASRASIVHIDIDPAEIGKNKQPHVSVCADVKLAL 335
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 327 ERFVEVARARKAAGtlPDRSEWVAQC--RRRKQTLQRRThFDDVpIKPQRVYEEMNRAFGPETRYVSAIGLSQIAAAQFL 404
Cdd:PLN02470 336 QGLNKLLEERKAKR--PDFSAWRAELdeQKEKFPLSYPT-FGDA-IPPQYAIQVLDELTDGNAIISTGVGQHQMWAAQWY 411
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 405 HVQQARHWINCGQAGPLGWTVPAALGVRVADPEAPVVAISGDYDFQFMLEELAVGAQFNLPYVHVVVNNSYLGLIRQAQR 484
Cdd:PLN02470 412 KYKEPRRWLTSGGLGAMGFGLPAAIGAAAANPDAIVVDIDGDGSFIMNIQELATIHVENLPVKIMVLNNQHLGMVVQWED 491
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 497628394 485 GFdmdYCVQLSFENINAPELGAYGV-DHVKVAEGLGCKAIRVHEPGDLLPAFEKagnlAAEHQVPVVVEVI 554
Cdd:PLN02470 492 RF---YKANRAHTYLGDPDAEAEIFpDFLKFAEGCKIPAARVTRKSDLREAIQK----MLDTPGPYLLDVI 555
|
|
| PRK08266 |
PRK08266 |
hypothetical protein; Provisional |
1-557 |
5.33e-90 |
|
hypothetical protein; Provisional
Pssm-ID: 181337 [Multi-domain] Cd Length: 542 Bit Score: 288.06 E-value: 5.33e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 1 MPKMTAAAAAVEILKREGVDHAFGVPGAAINPFYAAL-RARGGIGHTLARHVEGASHMAEGYTRTApGNIGVCVGTSGPA 79
Cdd:PRK08266 1 MTTMTGGEAIVAGLVAHGVDTVFGLPGAQLYWLFDALyKAGDRIRVIHTRHEQAAGYMAFGYARST-GRPGVCSVVPGPG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 80 GTDMITGLYSASADSVPILCITGQAPVARLHK---EDFQAVDISSIAQPVTKMAVTVLEPAQVPGAFQRAFHLMRSGRPG 156
Cdd:PRK08266 80 VLNAGAALLTAYGCNSPVLCLTGQIPSALIGKgrgHLHEMPDQLATLRSFTKWAERIEHPSEAPALVAEAFQQMLSGRPR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 157 PVLIDLPVDV--QLAEIEFDPDTyepMPLARPAATRAQAEKALAMLAAAERPLIVAGGGIvnADAAGLLVEFAELVDVPV 234
Cdd:PRK08266 160 PVALEMPWDVfgQRAPVAAAPPL---RPAPPPAPDPDAIAAAAALIAAAKNPMIFVGGGA--AGAGEEIRELAEMLQAPV 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 235 VPTLMGWGTIADDHPLMAGMVglqAAHRYgnatMLEADFVLGIGNR-------WANRhtggldtyTRGRTFVHVDIEPTQ 307
Cdd:PRK08266 235 VAFRSGRGIVSDRHPLGLNFA---AAYEL----WPQTDVVIGIGSRlelptfrWPWR--------PDGLKVIRIDIDPTE 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 308 IGRvFAPGYGIVSDAGAALERFVevARARKAAGTLPDRSEWVAQCRRRKQTLqrrthFDDVpiKPQRVYEEMNRAFGPET 387
Cdd:PRK08266 300 MRR-LKPDVAIVADAKAGTAALL--DALSKAGSKRPSRRAELRELKAAARQR-----IQAV--QPQASYLRAIREALPDD 369
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 388 RYVSAiGLSQIAAAQFLH--VQQARHWINCGQAGPLGWTVPAALGVRVADPEAPVVAISGDYDFQFMLEELAVGAQFNLP 465
Cdd:PRK08266 370 GIFVD-ELSQVGFASWFAfpVYAPRTFVTCGYQGTLGYGFPTALGAKVANPDRPVVSITGDGGFMFGVQELATAVQHNIG 448
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 466 YVHVVVNNSYLGLIRQAQRgfdmdycvqlsfENINAPELGA--YGVDHVKVAEGLGCKAIRVHEPGDLLPAFEKagnlAA 543
Cdd:PRK08266 449 VVTVVFNNNAYGNVRRDQK------------RRFGGRVVASdlVNPDFVKLAESFGVAAFRVDSPEELRAALEA----AL 512
|
570
....*....|....
gi 497628394 544 EHQVPVVVEVILER 557
Cdd:PRK08266 513 AHGGPVLIEVPVPR 526
|
|
| PRK06456 |
PRK06456 |
acetolactate synthase large subunit; |
1-557 |
1.02e-85 |
|
acetolactate synthase large subunit;
Pssm-ID: 180569 [Multi-domain] Cd Length: 572 Bit Score: 277.87 E-value: 1.02e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 1 MPkmTAAAAAVEILKREGVDHAFGVPGAAINPFYAAL---RARGGIGHTLARHVEGASHMAEGYTRtAPGNIGVCVGTSG 77
Cdd:PRK06456 1 MP--TGARILVDSLKREGVKVIFGIPGLSNMQIYDAFvedLANGELRHVLMRHEQAAAHAADGYAR-ASGVPGVCTATSG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 78 PAGTDMITGLYSASADSVPILCITGQAPVARLHKEDFQAVDISSIAQPVTKMAVTVLEPAQVPGAFQRAFHLMRSGRPGP 157
Cdd:PRK06456 78 PGTTNLVTGLITAYWDSSPVIAITGQVPRSVMGKMAFQEADAMGVFENVTKYVIGIKRIDEIPQWIKNAFYIATTGRPGP 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 158 VLIDLPVDVQLAEIEFDPDTYEPM-PLARPAAT---RAQAEKALAMLAAAERPLIVAGGGIVNADAAGLLVEFAELVDVP 233
Cdd:PRK06456 158 VVIDIPRDIFYEKMEEIKWPEKPLvKGYRDFPTridRLALKKAAEILINAERPIILVGTGVVWSNATPEVLELAELLHIP 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 234 VVPTLMGWGTIADDHPLMAGMVGLqaahrYGNA----TMLEADFVLGIGNRWANRH-TGGLDTYTRGRTFVHVDIEPTQI 308
Cdd:PRK06456 238 IVSTFPGKTAIPHDHPLYFGPMGY-----YGRAeasmAALESDAMLVVGARFSDRTfTSYDEMVETRKKFIMVNIDPTDG 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 309 GRVFAPGYGIVSDAGAALErfvEVARARKAAGTLPDRSEWVAQCRRRKQTL-QRRTHFDDVPIKPQRVYEEMNRAFGPET 387
Cdd:PRK06456 313 EKAIKVDVGIYGNAKIILR---ELIKAITELGQKRDRSAWLKRVKEYKEYYsQFYYTEENGKLKPWKIMKTIRQALPRDA 389
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 388 RYVSAIGLSQIAAAQFLHVQQARHWINCGQAGPLGWTVPAALGVRVADPEAPVVAISGDYDFQFMLEELAVGAQFNLPYV 467
Cdd:PRK06456 390 IVTTGVGQHQMWAEVFWEVLEPRTFLTSSGMGTMGFGLPAAMGAKLARPDKVVVDLDGDGSFLMTGTNLATAVDEHIPVI 469
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 468 HVVVNNSYLGLIRQAQRGFDMDYCVQLSFEniNAPelgaygvDHVKVAEGLGCKAIRVHEPGDLlpafEKAGNLAAEHQV 547
Cdd:PRK06456 470 SVIFDNRTLGLVRQVQDLFFGKRIVGVDYG--PSP-------DFVKLAEAFGALGFNVTTYEDI----EKSLKSAIKEDI 536
|
570
....*....|
gi 497628394 548 PVVVEVILER 557
Cdd:PRK06456 537 PAVIRVPVDK 546
|
|
| PRK08322 |
PRK08322 |
acetolactate synthase large subunit; |
4-553 |
2.72e-84 |
|
acetolactate synthase large subunit;
Pssm-ID: 236239 [Multi-domain] Cd Length: 547 Bit Score: 273.24 E-value: 2.72e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 4 MTAAAAAVEILKREGVDHAFGVPGAAINPFYAALRaRGGIGHTLARHVEGASHMAEGYTR-TapGNIGVCVGTSGPAGTD 82
Cdd:PRK08322 1 MKAADLFVKCLENEGVEYIFGIPGEENLDLLEALR-DSSIKLILTRHEQGAAFMAATYGRlT--GKAGVCLSTLGPGATN 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 83 MITGLYSASADSVPILCITGQAPVARLHKEDFQAVDISSIAQPVTKMAVTVLEPAQVPGAFQRAFHLMRSGRPGPVLIDL 162
Cdd:PRK08322 78 LVTGVAYAQLGGMPMVAITGQKPIKRSKQGSFQIVDVVAMMAPLTKWTRQIVSPDNIPEVVREAFRLAEEERPGAVHLEL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 163 PVDVqlAEIEFDPDTYEPMPLARPAATRAQAEKALAMLAAAERPLIVAGGGIVNADAAGLLVEFAELVDVPVVPTLMGWG 242
Cdd:PRK08322 158 PEDI--AAEETDGKPLPRSYSRRPYASPKAIERAAEAIQAAKNPLILIGAGANRKTASKALTEFVDKTGIPFFTTQMGKG 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 243 TIADDHPLMAGMVGLQaAHRYGNATMLEADFVLGIGN--------RWaNRHtggldtytRGRTFVHVDIEPTQIGRVFAP 314
Cdd:PRK08322 236 VIPETHPLSLGTAGLS-QGDYVHCAIEHADLIINVGHdviekppfFM-NPN--------GDKKVIHINFLPAEVDPVYFP 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 315 GYGIVSDAGAALERFVEVARAR---KAAGTLPDRSEWVAQcrrrkqtLQRRTHFDDVPIKPQRVYEEMNRAFGPETRYVS 391
Cdd:PRK08322 306 QVEVVGDIANSLWQLKERLADQphwDFPRFLKIREAIEAH-------LEEGADDDRFPMKPQRIVADLRKVMPDDDIVIL 378
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 392 AIGLSQIaaaQFlhvqqARHWiNCGQAGPL---------GWTVPAALGVRVADPEAPVVAISGDYDFQFMLEELAVGAQF 462
Cdd:PRK08322 379 DNGAYKI---WF-----ARNY-RAYEPNTClldnalatmGAGLPSAIAAKLVHPDRKVLAVCGDGGFMMNSQELETAVRL 449
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 463 NLPYVHVVVNNSYLGLIR--QAQRGFDmDYcvQLSFENinaPelgaygvDHVKVAEGLGCKAIRVHEPGDLLPAFEKAgn 540
Cdd:PRK08322 450 GLPLVVLILNDNAYGMIRwkQENMGFE-DF--GLDFGN---P-------DFVKYAESYGAKGYRVESADDLLPTLEEA-- 514
|
570
....*....|...
gi 497628394 541 LAAEhqVPVVVEV 553
Cdd:PRK08322 515 LAQP--GVHVIDC 525
|
|
| PRK08611 |
PRK08611 |
pyruvate oxidase; Provisional |
1-554 |
9.19e-78 |
|
pyruvate oxidase; Provisional
Pssm-ID: 181502 [Multi-domain] Cd Length: 576 Bit Score: 256.85 E-value: 9.19e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 1 MPKMTAAAAAVEILKREGVDHAFGVPGAAINPFYAALR-ARGGIGHTLARHVEGASHMAEGYTRTApGNIGVCVGTSGPA 79
Cdd:PRK08611 1 MAKIKAGEALVKLLQDWGIDHVYGIPGDSIDAVVDALRkEQDKIKFIQVRHEEVAALAAAAYAKLT-GKIGVCLSIGGPG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 80 GTDMITGLYSASADSVPILCITGQAPVARLHKEDFQAVDISSIAQPVTKMAVTVLEPAQVPGAFQRAFHLMRSGRPGPVL 159
Cdd:PRK08611 80 AIHLLNGLYDAKMDHVPVLALAGQVTSDLLGTDFFQEVNLEKMFEDVAVYNHQIMSAENLPEIVNQAIRTAYEKKGVAVL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 160 I---DLPVDVQLAEIEFDPDTYEPmplARPAATRAQAEKALAMLAAAERPLIVAGGGIVNADAAglLVEFAELVDVPVVP 236
Cdd:PRK08611 160 TipdDLPAQKIKDTTNKTVDTFRP---TVPSPKPKDIKKAAKLINKAKKPVILAGLGAKHAKEE--LLAFAEKAKIPIIH 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 237 TLMGWGTIADDHPLM---AGMVGLQAAHRygnaTMLEADFVLGIGNRWANRhtgglDTYTRGRTFVHVDIEPTQIGRVFA 313
Cdd:PRK08611 235 TLPAKGIIPDDHPYSlgnLGKIGTKPAYE----AMQEADLLIMVGTNYPYV-----DYLPKKAKAIQIDTDPANIGKRYP 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 314 PGYGIVSDAGAALERFVEVARARkaagtlPDRSeWVAQCRRRKQT----LQRRTHFDDVPIKPQRVYEEMNRAFGPETRY 389
Cdd:PRK08611 306 VNVGLVGDAKKALHQLTENIKHV------EDRR-FLEACQENMAKwwkwMEEDENNASTPIKPERVMAAIQKIADDDAVL 378
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 390 VSAIGLSQIAAAQFLHVQQARHWINCGQAGPLGWTVPAALGVRVADPEAPVVAISGDYDFQFMLEELAVGAQFNLPYVHV 469
Cdd:PRK08611 379 SVDVGTVTVWSARYLNLGTNQKFIISSWLGTMGCGLPGAIAAKIAFPDRQAIAICGDGGFSMVMQDFVTAVKYKLPIVVV 458
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 470 VVNNSYLGLIR--QAQRGfDMDYCVQLSfeninapelgayGVDHVKVAEGLGCKAIRVHEPGDLLPAFEKagnlAAEHQV 547
Cdd:PRK08611 459 VLNNQQLAFIKyeQQAAG-ELEYAIDLS------------DMDYAKFAEACGGKGYRVEKAEELDPAFEE----ALAQDK 521
|
....*..
gi 497628394 548 PVVVEVI 554
Cdd:PRK08611 522 PVIIDVY 528
|
|
| PRK06112 |
PRK06112 |
acetolactate synthase catalytic subunit; Validated |
2-556 |
9.28e-78 |
|
acetolactate synthase catalytic subunit; Validated
Pssm-ID: 235700 [Multi-domain] Cd Length: 578 Bit Score: 257.00 E-value: 9.28e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 2 PKMTAAAAAVEILKREGVDHAFG--VPGAAinpFYAALRArgGIGHTLARHVEGASHMAEGYTRTApGNIGVCVGTSGPA 79
Cdd:PRK06112 12 LNGTVAHAIARALKRHGVEQIFGqsLPSAL---FLAAEAI--GIRQIAYRTENAGGAMADGYARVS-GKVAVVTAQNGPA 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 80 GTDMITGLYSASADSVPILCITGQAPVARLHKEDFQAVDISSIAQPVTKMAVTVLEPAQVPGAFQRAFHLMRSGRPGPVL 159
Cdd:PRK06112 86 ATLLVAPLAEALKASVPIVALVQDVNRDQTDRNAFQELDHIALFQSCTKWVRRVTVAERIDDYVDQAFTAATSGRPGPVV 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 160 IDLPVDVQLAEIEF----DPDTYEPMPLARPAATRAQAEKALAMLAAAERPLIVAGGGIVNADAAGLLVEFAELVDVPVV 235
Cdd:PRK06112 166 LLLPADLLTAAAAApaapRSNSLGHFPLDRTVPAPQRLAEAASLLAQAQRPVVVAGGGVHISGASAALAALQSLAGLPVA 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 236 PTLMGWGTIADDHPLMAGMVGL----QAAHRYGNATMLEADFVLGIGNRWANRHTGGLDTYTRGRTFVHVDIEPTQIGRV 311
Cdd:PRK06112 246 TTNMGKGAVDETHPLSLGVVGSlmgpRSPGRHLRDLVREADVVLLVGTRTNQNGTDSWSLYPEQAQYIHIDVDGEEVGRN 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 312 FApGYGIVSDAGAALERFVEVARARKAAGTLPDRS---EWVAQCRRR-KQTLQRRTHFDDVPIKPQRVYEEMNRAFGPET 387
Cdd:PRK06112 326 YE-ALRLVGDARLTLAALTDALRGRDLAARAGRRAalePAIAAGREAhREDSAPVALSDASPIRPERIMAELQAVLTGDT 404
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 388 RYVSAIGLSQIAAAQFLHVQQA--RHWINCGQAGpLGWTVPAALGVRVADPEAPVVAISGDYDFQFMLEELAVGAQFNLP 465
Cdd:PRK06112 405 IVVADASYSSIWVANFLTARRAgmRFLTPRGLAG-LGWGVPMAIGAKVARPGAPVICLVGDGGFAHVWAELETARRMGVP 483
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 466 YVHVVVNNSYLGLIRQAQRGFDMDYCVQLSFEninapelgayGVDHVKVAEGLGCKAIRVHEPGDLLPAFEKAgnLAAeh 545
Cdd:PRK06112 484 VTIVVLNNGILGFQKHAETVKFGTHTDACHFA----------AVDHAAIARACGCDGVRVEDPAELAQALAAA--MAA-- 549
|
570
....*....|.
gi 497628394 546 QVPVVVEVILE 556
Cdd:PRK06112 550 PGPTLIEVITD 560
|
|
| PRK07524 |
PRK07524 |
5-guanidino-2-oxopentanoate decarboxylase; |
5-557 |
1.51e-77 |
|
5-guanidino-2-oxopentanoate decarboxylase;
Pssm-ID: 236041 [Multi-domain] Cd Length: 535 Bit Score: 255.28 E-value: 1.51e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 5 TAAAAAVEILKREGVDHAFGVPGAAINPFYAALrARGGIGHTLARHVEGASHMAEGYTRTApGNIGVCVGTSGPAGTDMI 84
Cdd:PRK07524 3 TCGEALVRLLEAYGVETVFGIPGVHTVELYRGL-AGSGIRHVTPRHEQGAGFMADGYARVS-GKPGVCFIITGPGMTNIA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 85 TGLYSASADSVPILCITGQAPVARLHKED---FQAVDISSIAQPVTKMAVTVLEPAQVPGAFQRAFHLMRSGRPGPVLID 161
Cdd:PRK07524 81 TAMGQAYADSIPMLVISSVNRRASLGKGRgklHELPDQRAMVAGVAAFSHTLMSAEDLPEVLARAFAVFDSARPRPVHIE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 162 LPVDVQLAEIEFDPdTYEPMPLARPAATRAQAEKALAMLAAAERPLIVAGGGIVNADAAglLVEFAELVDVPVVPTLMGW 241
Cdd:PRK07524 161 IPLDVLAAPADHLL-PAPPTRPARPGPAPAALAQAAERLAAARRPLILAGGGALAAAAA--LRALAERLDAPVALTINAK 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 242 GTIADDHPLMAGMVGLQAAHRygnATMLEADFVLGIGNRWANRHtggLDTYTRGR-----TFVHVDIEPTQIGRVFAPGY 316
Cdd:PRK07524 238 GLLPAGHPLLLGASQSLPAVR---ALIAEADVVLAVGTELGETD---YDVYFDGGfplpgELIRIDIDPDQLARNYPPAL 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 317 GIVSDAGAALERFVEvararkAAGTLPDRSEWvAQCRRRKQTLQRRTHFDDvPIKPQRVYEEMNRAFGPETRYVSAIGLS 396
Cdd:PRK07524 312 ALVGDARAALEALLA------RLPGQAAAADW-GAARVAALRQALRAEWDP-LTAAQVALLDTILAALPDAIFVGDSTQP 383
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 397 QIAAAQFLHVQQARHWINCGQA-GPLGWTVPAALGVRVADPEAPVVAISGDYDFQFMLEELAVGAQFNLPYVHVVVNNSY 475
Cdd:PRK07524 384 VYAGNLYFDADAPRRWFNASTGyGTLGYGLPAAIGAALGAPERPVVCLVGDGGLQFTLPELASAVEADLPLIVLLWNNDG 463
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 476 LGLIRqaqrgfdmDYCVQLSFE----NINAPelgaygvDHVKVAEGLGCKAIRVHEPGDLLPAFEKagnlAAEHQVPVVV 551
Cdd:PRK07524 464 YGEIR--------RYMVARDIEpvgvDPYTP-------DFIALARAFGCAAERVADLEQLQAALRA----AFARPGPTLI 524
|
....*.
gi 497628394 552 EVILER 557
Cdd:PRK07524 525 EVDQAC 530
|
|
| PRK08199 |
PRK08199 |
thiamine pyrophosphate protein; Validated |
1-556 |
3.03e-75 |
|
thiamine pyrophosphate protein; Validated
Pssm-ID: 181285 [Multi-domain] Cd Length: 557 Bit Score: 249.79 E-value: 3.03e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 1 MPKMTAAAAAVEILKREGVDHAFGVPGAAINPFYAALRARGGIGHTLARHVEGASHMAEGYTRtAPGNIGVCVGTSGPAG 80
Cdd:PRK08199 5 PRARTGGQILVDALRANGVERVFCVPGESYLAVLDALHDETDIRVIVCRQEGGAAMMAEAYGK-LTGRPGICFVTRGPGA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 81 TDMITGLYSASADSVPILCITGQapVARLHK--EDFQAVDISSIAQPVTKMAVTVLEPAQVPGAFQRAFHLMRSGRPGPV 158
Cdd:PRK08199 84 TNASIGVHTAFQDSTPMILFVGQ--VARDFRerEAFQEIDYRRMFGPMAKWVAEIDDAARIPELVSRAFHVATSGRPGPV 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 159 LIDLPVDVqLAEIEFDPDTyEPMPLARPAATRAQAEKALAMLAAAERPLIVAGGGIVNADAAGLLVEFAELVDVPVVPTL 238
Cdd:PRK08199 162 VLALPEDV-LSETAEVPDA-PPYRRVAAAPGAADLARLAELLARAERPLVILGGSGWTEAAVADLRAFAERWGLPVACAF 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 239 MGWGTIADDHPLMAGMVGLQAAHRYGnATMLEADFVLGIGNRWANRHTGG---LDTYTRGRTFVHVDIEPTQIGRVFAPG 315
Cdd:PRK08199 240 RRQDLFDNRHPNYAGDLGLGINPALA-ARIREADLVLAVGTRLGEVTTQGytlLDIPVPRQTLVHVHPDAEELGRVYRPD 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 316 YGIVSDAGAALERFvevarARKAAGTLPDRSEWVAQCRRRkqtlqrrthfddvpikpqrvYEemnrAFGPETRYVSAIGL 395
Cdd:PRK08199 319 LAIVADPAAFAAAL-----AALEPPASPAWAEWTAAAHAD--------------------YL----AWSAPLPGPGAVQL 369
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 396 SQIAA-------------------AQFLH-VQQARHWinCGQAGP----LGWTVPAALGVRVADPEAPVVAISGDYDFQF 451
Cdd:PRK08199 370 GEVMAwlrerlpadaiitngagnyATWLHrFFRFRRY--RTQLAPtsgsMGYGLPAAIAAKLLFPERTVVAFAGDGCFLM 447
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 452 MLEELAVGAQFNLPYVHVVVNNSYLGLIRQAQ-RGFDmdycvqlsfENINAPELGayGVDHVKVAEGLGCKAIRVHEPGD 530
Cdd:PRK08199 448 NGQELATAVQYGLPIIVIVVNNGMYGTIRMHQeREYP---------GRVSGTDLT--NPDFAALARAYGGHGETVERTED 516
|
570 580
....*....|....*....|....*.
gi 497628394 531 LLPAFEKAgnLAAehQVPVVVEVILE 556
Cdd:PRK08199 517 FAPAFERA--LAS--GKPALIEIRID 538
|
|
| PRK06154 |
PRK06154 |
thiamine pyrophosphate-requiring protein; |
4-562 |
2.98e-71 |
|
thiamine pyrophosphate-requiring protein;
Pssm-ID: 235718 [Multi-domain] Cd Length: 565 Bit Score: 239.33 E-value: 2.98e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 4 MTAAAAAVEILKREGVDHAFGVPgaaINPFYAAlRARGGIGHTLARHVEGASHMAEGYTRTAPG-NIGVCVGTSGPAGTD 82
Cdd:PRK06154 20 MKVAEAVAEILKEEGVELLFGFP---VNELFDA-AAAAGIRPVIARTERVAVHMADGYARATSGeRVGVFAVQYGPGAEN 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 83 MITGLYSASADSVPILCITGQAPVARLHKE-DFQAvdiSSIAQPVTKMAVTVLEPAQVPGAFQRAFHLMRSGRPGPVLID 161
Cdd:PRK06154 96 AFGGVAQAYGDSVPVLFLPTGYPRGSTDVApNFES---LRNYRHITKWCEQVTLPDEVPELMRRAFTRLRNGRPGPVVLE 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 162 LPVDVQLAEIEFDPDTYEPMPLARPAATRAQAEKALAMLAAAERPLIVAGGGIVNADAAGLLVEFAELVDVPVVPTLMGW 241
Cdd:PRK06154 173 LPVDVLAEELDELPLDHRPSRRSRPGADPVEVVEAAALLLAAERPVIYAGQGVLYAQATPELKELAELLEIPVMTTLNGK 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 242 GTIADDHPLMAGMVGL----QAAHrygnaTMLEADFVLGIGNRWANRHTGGldTYTRGRTFVHVDIEPTQIGRVFAPGYG 317
Cdd:PRK06154 253 SAFPEDHPLALGSGGRarpaTVAH-----FLREADVLFGIGCSLTRSYYGL--PMPEGKTIIHSTLDDADLNKDYPIDHG 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 318 IVSDAGAALERFVEVARARkaAGTLP-DRSEWVAQCRRRKQTLQRRTH----FDDVPIKPQRVYEEMNRAFGPETRYVSA 392
Cdd:PRK06154 326 LVGDAALVLKQMIEELRRR--VGPDRgRAQQVAAEIEAVRAAWLAKWMpkltSDSTPINPYRVVWELQHAVDIKTVIITH 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 393 -IGLSQIAAAQFLHVQQARHWINCGQAGPLGWTVPAALGVRVADPEAPVVAISGDYDFQFMLEELAVGAQFNLPYVHVVV 471
Cdd:PRK06154 404 dAGSPRDQLSPFYVASRPGSYLGWGKTTQLGYGLGLAMGAKLARPDALVINLWGDAAFGMTGMDFETAVRERIPILTILL 483
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 472 NNSYLGLirqaqrgfdMDYCVQLSFENINAPELGAygvDHVKVAEGLGCKAIRVHEPGDLLPAFEKAGNlAAEHQVPVVV 551
Cdd:PRK06154 484 NNFSMGG---------YDKVMPVSTTKYRATDISG---DYAAIARALGGYGERVEDPEMLVPALLRALR-KVKEGTPALL 550
|
570
....*....|.
gi 497628394 552 EVILERVTNIS 562
Cdd:PRK06154 551 EVITSEETALS 561
|
|
| PRK07525 |
PRK07525 |
sulfoacetaldehyde acetyltransferase; Validated |
1-558 |
5.00e-69 |
|
sulfoacetaldehyde acetyltransferase; Validated
Pssm-ID: 236042 [Multi-domain] Cd Length: 588 Bit Score: 234.12 E-value: 5.00e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 1 MPKMTAAAAAVEILKREGVDHAFGVPGAAINPFyAALRARGGIGHTLARHVEGASHMAEGYTRtAPGNIGVCVGTSGPAG 80
Cdd:PRK07525 3 KMKMTPSEAFVETLQAHGITHAFGIIGSAFMDA-SDLFPPAGIRFIDVAHEQNAGHMADGYTR-VTGRMGMVIGQNGPGI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 81 TDMITGLYSASADSVPILCITGQAPVARLHKEDFQAVDISSIAQPVTKMAVTVLEPAQVPGAFQRAFHLMRSGRpGPVLI 160
Cdd:PRK07525 81 TNFVTAVATAYWAHTPVVLVTPQAGTKTIGQGGFQEAEQMPMFEDMTKYQEEVRDPSRMAEVLNRVFDKAKRES-GPAQI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 161 DLPVDVQLAEIefDPDTYEPMPLARPAATRAQAEKALAMLAAAERPLIVAGGGIVNADAAGLLVEFAELVDVPVVPTLMG 240
Cdd:PRK07525 160 NIPRDYFYGVI--DVEIPQPVRLERGAGGEQSLAEAAELLSEAKFPVILSGAGVVLSDAIEECKALAERLDAPVACGYLH 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 241 WGTIADDHPLMAGMVGLQ---AAHRygnaTMLEADFVLGIGNRWANRHT---GGLDTYTRGRTFVHVDIEPTQIGRVFAP 314
Cdd:PRK07525 238 NDAFPGSHPLWVGPLGYNgskAAME----LIAKADVVLALGTRLNPFGTlpqYGIDYWPKDAKIIQVDINPDRIGLTKKV 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 315 GYGIVSDAGAALERFVEVARARKAA-GTLPDRSEWVAQCRRR-KQTLQRRTHFDDVP---------------IKPQRVYE 377
Cdd:PRK07525 314 SVGICGDAKAVARELLARLAERLAGdAGREERKALIAAEKSAwEQELSSWDHEDDDPgtdwneeararkpdyMHPRQALR 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 378 EMNRAFGPETRYVSAIG-LSQIAAAqFLHVQQARHWINCGQAGPLGWTVPAALGVRVADPEAPVVAISGDYDFQFMLEEL 456
Cdd:PRK07525 394 EIQKALPEDAIVSTDIGnNCSIANS-YLRFEKGRKYLAPGSFGNCGYAFPAIIGAKIACPDRPVVGFAGDGAWGISMNEV 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 457 AVGAQFNLPYVHVVVNNSYLGLIRQAQRGFDMDycvqlsfeNINAPELGAyGVDHVKVAEGLGCKAIRVHEPGDLLPAFE 536
Cdd:PRK07525 473 MTAVRHNWPVTAVVFRNYQWGAEKKNQVDFYNN--------RFVGTELDN-NVSYAGIAEAMGAEGVVVDTQEELGPALK 543
|
570 580
....*....|....*....|..
gi 497628394 537 KAGNlAAEHQVPVVVEVILERV 558
Cdd:PRK07525 544 RAID-AQNEGKTTVIEIMCNQE 564
|
|
| PRK08617 |
PRK08617 |
acetolactate synthase AlsS; |
2-568 |
2.06e-56 |
|
acetolactate synthase AlsS;
Pssm-ID: 236312 [Multi-domain] Cd Length: 552 Bit Score: 198.93 E-value: 2.06e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 2 PKMTAAAAAVEILKREGVDHAFGVPGAAINPFYAALRARGgIGHTLARHVEGASHMAEGYTRTApGNIGVCVGTSGPAGT 81
Cdd:PRK08617 3 KKKYGADLVVDSLINQGVKYVFGIPGAKIDRVFDALEDSG-PELIVTRHEQNAAFMAAAIGRLT-GKPGVVLVTSGPGVS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 82 DMITGLYSASADSVPILCITGQAPVARLHKEDFQAVDISSIAQPVTKMAVTVLEPAQVPGAFQRAFHLMRSGRPGPVLID 161
Cdd:PRK08617 81 NLATGLVTATAEGDPVVAIGGQVKRADRLKRTHQSMDNVALFRPITKYSAEVQDPDNLSEVLANAFRAAESGRPGAAFVS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 162 LPVDVQLAEIEFDPdtYEPMPLARP-AATRAQAEKALAMLAAAERPLIVAGGGIVNADAAGLLVEFAELVDVPVVPTLMG 240
Cdd:PRK08617 161 LPQDVVDAPVTSKA--IAPLSKPKLgPASPEDINYLAELIKNAKLPVLLLGMRASSPEVTAAIRRLLERTNLPVVETFQA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 241 WGTIADDH-PLMAGMVGL---QAahryGNATMLEADFVLGIG--------NRWaNRHtggldtytRGRTFVHVDIEPTQI 308
Cdd:PRK08617 239 AGVISRELeDHFFGRVGLfrnQP----GDELLKKADLVITIGydpieyepRNW-NSE--------GDATIIHIDVLPAEI 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 309 GRVFAPGYGIVSDAGAALERFVEVARARKaagtLPDRS-EWVAQCRRRKQTLQRRTHFDD-VPIKPQRVYEEMNRAFGPE 386
Cdd:PRK08617 306 DNYYQPERELIGDIAATLDLLAEKLDGLS----LSPQSlEILEELRAQLEELAERPARLEeGAVHPLRIIRALQDIVTDD 381
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 387 TRYVSAIGLSQIAAAQFLHVQQARHW-INCGQAgPLGWTVPAALGVRVADPEAPVVAISGDYDFQFMLEELAVGAQFNLP 465
Cdd:PRK08617 382 TTVTVDVGSHYIWMARYFRSYEPRHLlFSNGMQ-TLGVALPWAIAAALVRPGKKVVSVSGDGGFLFSAMELETAVRLKLN 460
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 466 YVHVVVNNSYLGLIR-QAQRGFDMDYCVqlsfeninapELGayGVDHVKVAEGLGCKAIRVHEPGDLLPAFEKAgnLAAE 544
Cdd:PRK08617 461 IVHIIWNDGHYNMVEfQEEMKYGRSSGV----------DFG--PVDFVKYAESFGAKGLRVTSPDELEPVLREA--LATD 526
|
570 580
....*....|....*....|....
gi 497628394 545 hqVPVVVEVILERVTNISMGTEID 568
Cdd:PRK08617 527 --GPVVIDIPVDYSDNIKLMEQLL 548
|
|
| TPP_PYR_POX_like |
cd07035 |
Pyrimidine (PYR) binding domain of POX and related proteins; Thiamine pyrophosphate (TPP ... |
9-164 |
5.72e-52 |
|
Pyrimidine (PYR) binding domain of POX and related proteins; Thiamine pyrophosphate (TPP family), pyrimidine (PYR) binding domain of pyruvate oxidase (POX) and related protiens subfamily. The PYR domain is found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. TPP binds in the cleft formed by a PYR domain and a PP domain. The PYR domain, binds the aminopyrimidine ring of TPP, the PP domain binds the diphosphate residue. A polar interaction between the conserved glutamate of the PYR domain and the N1' of the TPP aminopyrimidine ring is shared by most TPP-dependent enzymes, and participates in the activation of TPP. For glyoxylate carboligase, which belongs to this subfamily, but lacks this conserved glutamate, the rate of the initial TPP activation step is reduced but the ensuing steps of the enzymic reaction proceed efficiently. The PYR and PP domains have a common fold, but do not share strong sequence conservation. The PP domain is not included in this sub-family. Most TPP-dependent enzymes have the PYR and PP domains on the same subunit although these domains can be alternatively arranged in the primary structure. TPP-dependent enzymes are multisubunit proteins, the smallest catalytic unit being a dimer-of-active sites, for many the active sites lie between PP and PYR domains on different subunits. POX decarboxylates pyruvate, producing hydrogen peroxide and the energy-storage metabolite acetylphosphate. This subfamily includes pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC catalyzes the conversion of pyruvate to acetaldehyde and CO2 in alcoholic fermentation. IPDC plays a role in the indole-3-pyruvic acid (IPA) pathway in plants and various plant-associated bacteria, it catalyzes the decarboxylation of IPA to IAA. This subfamily also includes the large catalytic subunit of acetohydroxyacid synthase (AHAS). AHAS catalyzes the condensation of two molecules of pyruvate to give the acetohydroxyacid, 2-acetolactate, a precursor of the branched chain amino acids, valine and leucine. AHAS also catalyzes the condensation of pyruvate and 2-ketobutyrate to form 2-aceto-2-hydroxybutyrate in isoleucine biosynthesis. Methanococcus jannaschii sulfopyruvate decarboxylase (MjComDE) and phosphonopyruvate decarboxylase (PpyrDc) also belong to this subfamily. PpyrDc is a homotrimeric enzyme having the PP and PYR domains tandemly arranged on the same subunit. It functions in the biosynthesis of C-P compounds such as bialaphos tripeptide in Streptomyces hygroscopicus. MjComDE is a dodecamer having the PYR and PP domains on different subunits, it has six alpha (PYR/ComD) subunits and six beta (PP/ComE) subunits. MjComDE catalyzes the decarboxylation of sulfopyruvic acid to sulfoacetaldehyde in the coenzyme M pathway.
Pssm-ID: 132918 [Multi-domain] Cd Length: 155 Bit Score: 175.03 E-value: 5.72e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 9 AAVEILKREGVDHAFGVPGAAINPFYAALRaRGGIGHTLARHVEGASHMAEGYTRTApGNIGVCVGTSGPAGTDMITGLY 88
Cdd:cd07035 2 ALVEALKAEGVDHVFGVPGGAILPLLDALA-RSGIRYILVRHEQGAVGMADGYARAT-GKPGVVLVTSGPGLTNAVTGLA 79
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 497628394 89 SASADSVPILCITGQAPVARLHKEDFQAVDISSIAQPVTKMAVTVLEPAQVPGAFQRAFHLMRSGRPGPVLIDLPV 164
Cdd:cd07035 80 NAYLDSIPLLVITGQRPTAGEGRGAFQEIDQVALFRPITKWAYRVTSPEEIPEALRRAFRIALSGRPGPVALDLPK 155
|
|
| PRK06457 |
PRK06457 |
pyruvate dehydrogenase; Provisional |
5-556 |
1.01e-51 |
|
pyruvate dehydrogenase; Provisional
Pssm-ID: 180570 [Multi-domain] Cd Length: 549 Bit Score: 186.19 E-value: 1.01e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 5 TAAAAAVEILKREGVDHAFGVPGAAINPFYAALRaRGGIGHTLARHVEGAShMAEGYTRTAPGNIGVCVGTSGPAGTDMI 84
Cdd:PRK06457 3 SVAEVIIRVLEDNGIQRIYGIPGDSIDPLVDAIR-KSKVKYVQVRHEEGAA-LAASVEAKITGKPSACMGTSGPGSIHLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 85 TGLYSASADSVPILCITGQAPVARLHKEDFQAVDISSIAQPVTKMAVTVLEPAQVPGAFQRAFHLMRSGRpGPVLIDLPV 164
Cdd:PRK06457 81 NGLYDAKMDHAPVIALTGQVESDMIGHDYFQEVNLTKLFDDVAVFNQILINPENAEYIIRRAIREAISKR-GVAHINLPV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 165 DVQLAEIEFDPDTYEPMPLARPAATRAQAEKalaMLAAAERPLIVAGGGIVnaDAAGLLVEFAELVDVPVVPTLMGWGTI 244
Cdd:PRK06457 160 DILRKSSEYKGSKNTEVGKVKYSIDFSRAKE---LIKESEKPVLLIGGGTR--GLGKEINRFAEKIGAPIIYTLNGKGIL 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 245 ADDHPLMAGMVGLQAAHRYGNAtMLEADFVLGIGNRWANrhtggLDTYTRGRTFVHVDIEPTQIGRVFAPGYGIVSDAGA 324
Cdd:PRK06457 235 PDLDPKVMGGIGLLGTKPSIEA-MDKADLLIMLGTSFPY-----VNFLNKSAKVIQVDIDNSNIGKRLDVDLSYPIPVAE 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 325 ALERFVEVARARKAAGTLPDRSEWvaqcrrrKQTLQRRTHFDDVPIKPQRVYEEMNRAFGPETRYVSAIGLSQIAAAQFL 404
Cdd:PRK06457 309 FLNIDIEEKSDKFYEELKGKKEDW-------LDSISKQENSLDKPMKPQRVAYIVSQKCKKDAVIVTDTGNVTMWTARHF 381
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 405 HVQQARHWINCGQAGPLGWTVPAALGVRVA-DPEAPVVAISGDYDFQFMLEELAVGAQFNLPYVHVVVNNSYLGLIRQAQ 483
Cdd:PRK06457 382 RASGEQTFIFSAWLGSMGIGVPGSVGASFAvENKRQVISFVGDGGFTMTMMELITAKKYDLPVKIIIYNNSKLGMIKFEQ 461
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 497628394 484 rgfdmdycvqlsfENINAPELGA--YGVDHVKVAEGLGCKAIRVHEPGDLLPAFEKAGNlaaeHQVPVVVEVILE 556
Cdd:PRK06457 462 -------------EVMGYPEWGVdlYNPDFTKIAESIGFKGFRLEEPKEAEEIIEEFLN----TKGPAVLDAIVD 519
|
|
| TPP_enzyme_N |
pfam02776 |
Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; |
6-172 |
1.75e-49 |
|
Thiamine pyrophosphate enzyme, N-terminal TPP binding domain;
Pssm-ID: 460690 [Multi-domain] Cd Length: 169 Bit Score: 168.95 E-value: 1.75e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 6 AAAAAVEILKREGVDHAFGVPGAAINPFYAALRARGGIGHTLARHVEGASHMAEGYTRTApGNIGVCVGTSGPAGTDMIT 85
Cdd:pfam02776 1 GAEALADVLKALGVDTVFGVPGGHILPLLDALAKSPGIRYVLTRHEQGAAFAADGYARAT-GKPGVVLVTSGPGATNALT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 86 GLYSASADSVPILCITGQAPVARLHKEDFQA-VDISSIAQPVTKMAVTVLEPAQVPGAFQRAFHLMRSGRPGPVLIDLPV 164
Cdd:pfam02776 80 GLANAYVDSVPLLVISGQRPRSLVGRGALQQeLDQLALFRPVTKWAVRVTSADEIPEVLRRAFRAALSGRPGPVYLEIPL 159
|
....*...
gi 497628394 165 DVQLAEIE 172
Cdd:pfam02776 160 DVLLEEVD 167
|
|
| PRK05858 |
PRK05858 |
acetolactate synthase; |
6-554 |
1.82e-48 |
|
acetolactate synthase;
Pssm-ID: 235629 [Multi-domain] Cd Length: 542 Bit Score: 177.22 E-value: 1.82e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 6 AAAAAVEILKREGVDHAFGVPGAAINPFYAALRaRGGIGHTLARHVEGASHMAEGY---TRTApgniGVCVGTSGPAGTD 82
Cdd:PRK05858 7 AGRLAARRLKAHGVDTMFTLSGGHLFPLYDGAR-EEGIRLIDVRHEQTAAFAAEAWaklTRVP----GVAVLTAGPGVTN 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 83 MITGLYSASADSVPILCITGQAPVARLHKEDFQAVDISSIAQPVTKMAVTVLEPAQVPGAFQRAFHLMRSGRPGPVLIDL 162
Cdd:PRK05858 82 GMSAMAAAQFNQSPLVVLGGRAPALRWGMGSLQEIDHVPFVAPVTKFAATAQSAENAGRLVDQALQAAVTPHRGPVFVDF 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 163 PVDV--QLAEIEFDPDTYEPMPLARPAATRAQAEKAlAMLAAAERPLIVAGGGIVNADAAGLLVEFAELVDVPVVPTLMG 240
Cdd:PRK05858 162 PMDHafSMADDDGRPGALTELPAGPTPDPDALARAA-GLLAEAQRPVIMAGTDVWWGHAEAALLRLAEELGIPVLMNGMG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 241 WGTIADDHPLmagmvglqAAHRYGNATMLEADFVLGIGNRWANRHTGGLdtYTRGRTFVHVDIEPTQIGRVFAPGYGIVS 320
Cdd:PRK05858 241 RGVVPADHPL--------AFSRARGKALGEADVVLVVGVPMDFRLGFGV--FGGTAQLVHVDDAPPQRAHHRPVAAGLYG 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 321 DAGAALERFVEvararkAAGTLPDRSEWVAQCRRRKQTLQRRTHF----DDVPIKPQRVYEEMNRAFGPETRYVSAIGLS 396
Cdd:PRK05858 311 DLSAILSALAG------AGGDRTDHQGWIEELRTAETAARARDAAeladDRDPIHPMRVYGELAPLLDRDAIVIGDGGDF 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 397 QIAAAQFLHVQQARHWINCGQAGPLGWTVPAALGVRVADPEAPVVAISGDYDFQFMLEELAVGAQFNLPYVHVVVNNSYL 476
Cdd:PRK05858 385 VSYAGRYIDPYRPGCWLDPGPFGCLGTGPGYALAARLARPSRQVVLLQGDGAFGFSLMDVDTLVRHNLPVVSVIGNNGIW 464
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 477 GLIR---QAQRGFDMdycvqlsfeninAPELgAYGVDHVKVAEGLGCKAIRVHEPGDLLPAFEKagnlAAEHQVPVVVEV 553
Cdd:PRK05858 465 GLEKhpmEALYGYDV------------AADL-RPGTRYDEVVRALGGHGELVTVPAELGPALER----AFASGVPYLVNV 527
|
.
gi 497628394 554 I 554
Cdd:PRK05858 528 L 528
|
|
| PRK07064 |
PRK07064 |
thiamine pyrophosphate-binding protein; |
3-553 |
5.43e-47 |
|
thiamine pyrophosphate-binding protein;
Pssm-ID: 180820 [Multi-domain] Cd Length: 544 Bit Score: 172.87 E-value: 5.43e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 3 KMTAAAAAVEILKREGVDHAFGVPGAAINPFYAALRARGGIGHTLARHVEGASHMAEGYTRTApGNIGVCVGTSGPAGTD 82
Cdd:PRK07064 2 KVTVGELIAAFLEQCGVKTAFGVISIHNMPILDAIGRRGKIRFVPARGEAGAVNMADAHARVS-GGLGVALTSTGTGAGN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 83 MITGLYSASADSVPILCITGQAPVARLHKED---FQAVDISSIAQPVTKMAVTVLEPAQVPGAFQRAFHLMRSGRPGPVL 159
Cdd:PRK07064 81 AAGALVEALTAGTPLLHITGQIETPYLDQDLgyiHEAPDQLTMLRAVSKAAFRVRSAETALATIREAVRVALTAPTGPVS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 160 IDLPVDVQLAEIEFdPDTYEPMPLARPAATRAQAEKALAMLAAAERPLIVAGGGIVNADAagllvEFAELVD--VPVVPT 237
Cdd:PRK07064 161 VEIPIDIQAAEIEL-PDDLAPVHVAVPEPDAAAVAELAERLAAARRPLLWLGGGARHAGA-----EVKRLVDlgFGVVTS 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 238 LMGWGTIADDHPLMAGMVGLQAAhryGNATMLEADFVLGIGNRWANRHTgglDTYTRG--RTFVHVDIEPTQIGRVFAPG 315
Cdd:PRK07064 235 TQGRGVVPEDHPASLGAFNNSAA---VEALYKTCDLLLVVGSRLRGNET---LKYSLAlpRPLIRVDADAAADGRGYPND 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 316 YGIVSDAGAALERFVEvararKAAGTLPDRSEWVAQCRRRKQtlQRRTHFDDVPIKPQRVYEEMNRAFGPETRYVSAIGL 395
Cdd:PRK07064 309 LFVHGDAARVLARLAD-----RLEGRLSVDPAFAADLRAARE--AAVADLRKGLGPYAKLVDALRAALPRDGNWVRDVTI 381
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 396 SQIA-AAQFLHVQQARHWINcGQAGPLGWTVPAALGVRVADPEAPVVAISGDYDFQFMLEELAVGAQFNLPYVHVVVNNS 474
Cdd:PRK07064 382 SNSTwGNRLLPIFEPRANVH-ALGGGIGQGLAMAIGAALAGPGRKTVGLVGDGGLMLNLGELATAVQENANMVIVLMNDG 460
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 475 YLGLIRQAQRG-FDMDYCvqlsFENINAPelgaygvDHVKVAEGLGCKAIRVHEPGDllpaFEKAGNLAAEHQVPVVVEV 553
Cdd:PRK07064 461 GYGVIRNIQDAqYGGRRY----YVELHTP-------DFALLAASLGLPHWRVTSADD----FEAVLREALAKEGPVLVEV 525
|
|
| PRK08327 |
PRK08327 |
thiamine pyrophosphate-requiring protein; |
4-558 |
1.21e-46 |
|
thiamine pyrophosphate-requiring protein;
Pssm-ID: 236243 [Multi-domain] Cd Length: 569 Bit Score: 172.49 E-value: 1.21e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 4 MTAAAAAVEILKREGVDHAFGVPG---AAINPFYAALRARGgigHTLAR-----HVEGASHMAEGYTRTA--PGNIGVCV 73
Cdd:PRK08327 7 YTAAELFLELLKELGVDYIFINSGtdyPPIIEAKARARAAG---RPLPEfvicpHEIVAISMAHGYALVTgkPQAVMVHV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 74 --GTSGPAGtdmitGLYSASADSVPILCITGQAPVA----------RLH--KEDFqavDISSIAQPVTKMAVTVLEPAQV 139
Cdd:PRK08327 84 dvGTANALG-----GVHNAARSRIPVLVFAGRSPYTeegelgsrntRIHwtQEMR---DQGGLVREYVKWDYEIRRGDQI 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 140 PGAFQRAFHLMRSGRPGPVLIDLPVDVQLAEIE-FDPDTYEPMPLARPAATRAQAEKALAMLAAAERPLIVAGGGIVNAD 218
Cdd:PRK08327 156 GEVVARAIQIAMSEPKGPVYLTLPREVLAEEVPeVKADAGRQMAPAPPAPDPEDIARAAEMLAAAERPVIITWRAGRTAE 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 219 AAGLLVEFAELVDVPVV---PTLMgwgTIADDHPLMAGMVglqaahryGNATMLEADFVLGIGNR--WANRHTGGLDtyt 293
Cdd:PRK08327 236 GFASLRRLAEELAIPVVeyaGEVV---NYPSDHPLHLGPD--------PRADLAEADLVLVVDSDvpWIPKKIRPDA--- 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 294 rGRTFVHVDIEPTQiGRVfaPGYG------IVSDAGAALERFVEVARAR-KAAGTLPDRSEWVAQCRRRKQTLQRRTHF- 365
Cdd:PRK08327 302 -DARVIQIDVDPLK-SRI--PLWGfpcdlcIQADTSTALDQLEERLKSLaSAERRRARRRRAAVRELRIRQEAAKRAEIe 377
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 366 ---DDVPIKPQRVYEEMNRAFGPETRYVSaiglSQIAAAQFLHVQQARHWINCGQAGPLGWTVPAALGVRVADPEAPVVA 442
Cdd:PRK08327 378 rlkDRGPITPAYLSYCLGEVADEYDAIVT----EYPFVPRQARLNKPGSYFGDGSAGGLGWALGAALGAKLATPDRLVIA 453
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 443 ISGDYDFQFMLEE--LAVGAQFNLPYVHVVVNNSYLGLIRQAQRGF-------DMDYCVQLSFEniNAPELGaygvdhvK 513
Cdd:PRK08327 454 TVGDGSFIFGVPEaaHWVAERYGLPVLVVVFNNGGWLAVKEAVLEVypegyaaRKGTFPGTDFD--PRPDFA-------K 524
|
570 580 590 600
....*....|....*....|....*....|....*....|....*
gi 497628394 514 VAEGLGCKAIRVHEPGDLLPAFEKAGNLAAEHQVPVVVEVILERV 558
Cdd:PRK08327 525 IAEAFGGYGERVEDPEELKGALRRALAAVRKGRRSAVLDVIVDRV 569
|
|
| PRK09124 |
PRK09124 |
ubiquinone-dependent pyruvate dehydrogenase; |
3-557 |
3.89e-46 |
|
ubiquinone-dependent pyruvate dehydrogenase;
Pssm-ID: 181661 [Multi-domain] Cd Length: 574 Bit Score: 171.32 E-value: 3.89e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 3 KMTAAAAAVEILKREGVDHAFGVPGAAINPFYAALRARGGIGHTLARHVEGAShMAEGYTRTAPGNIGVCVGTSGPAGTD 82
Cdd:PRK09124 2 KQTVADYIAKTLEQAGVKRIWGVTGDSLNGLSDSLRRMGTIEWMHTRHEEVAA-FAAGAEAQLTGELAVCAGSCGPGNLH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 83 MITGLYSASADSVPILCITGQAPVARLHKEDFQAVDISSIAQPVTKMAVTVLEPAQVPGAFQRAfhlMRS--GRPGPVLI 160
Cdd:PRK09124 81 LINGLFDCHRNHVPVLAIAAHIPSSEIGSGYFQETHPQELFRECSHYCELVSNPEQLPRVLAIA---MRKaiLNRGVAVV 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 161 DLPVDVQLAEIEFD--PDTYEPM-PLARPAAtrAQAEKALAMLAAAERPLIVAGGGIVNADAAglLVEFAELVDVPVVPT 237
Cdd:PRK09124 158 VLPGDVALKPAPERatPHWYHAPqPVVTPAE--EELRKLAALLNGSSNITLLCGSGCAGAHDE--LVALAETLKAPIVHA 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 238 LMGWGTIADDHPLMAGMVGLqAAHRYGNATMLEADFVLGIGNRWANRhtgglDTYTRGRTFVHVDIEPTQIGRVFAPGYG 317
Cdd:PRK09124 234 LRGKEHVEYDNPYDVGMTGL-IGFSSGYHAMMNCDTLLMLGTDFPYR-----QFYPTDAKIIQIDINPGSLGRRSPVDLG 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 318 IVSDAGAALERFVEVARARKAAGTLPDRSEWVAQCRRRKQTLQRRTHfDDVPIKPQRVYEEMNRAFGPETRYVSAIGLSQ 397
Cdd:PRK09124 308 LVGDVKATLAALLPLLEEKTDRKFLDKALEHYRKARKGLDDLAVPSD-GGKPIHPQYLARQISEFAADDAIFTCDVGTPT 386
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 398 IAAAQFLHVQQARHWINCGQAGPLGWTVPAALGVRVADPEAPVVAISGDYDFQFMLEELAVGAQFNLPYVHVVVNNSYLG 477
Cdd:PRK09124 387 VWAARYLKMNGKRRLLGSFNHGSMANAMPQALGAQAAHPGRQVVALSGDGGFSMLMGDFLSLVQLKLPVKIVVFNNSVLG 466
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 478 LIRQAQR--GFdMDYCVQLSFENINApelgaygvdhvkVAEGLGCKAIRVHEPGDLLPAFEKAgnLAaeHQVPVVVEVIL 555
Cdd:PRK09124 467 FVAMEMKagGY-LTDGTDLHNPDFAA------------IAEACGITGIRVEKASELDGALQRA--FA--HDGPALVDVVT 529
|
..
gi 497628394 556 ER 557
Cdd:PRK09124 530 AK 531
|
|
| PRK08273 |
PRK08273 |
thiamine pyrophosphate protein; Provisional |
4-554 |
4.34e-44 |
|
thiamine pyrophosphate protein; Provisional
Pssm-ID: 181344 [Multi-domain] Cd Length: 597 Bit Score: 165.85 E-value: 4.34e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 4 MTAAAAAVEILKREGVDHAFGVPGAAINPFYAAL-RARGGIGHTLARHVEGASHMAEGYTRTApGNIGVCVGTSGPAGTD 82
Cdd:PRK08273 3 QTVADFILERLREWGVRRVFGYPGDGINGLLGALgRADDKPEFVQARHEEMAAFMAVAHAKFT-GEVGVCLATSGPGAIH 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 83 MITGLYSASADSVPILCITGQAPVARLHKEDFQAVDISSIAQPV-TKMAVTVLEPAQVPGAFQRAFHLMRSGRpGPVLID 161
Cdd:PRK08273 82 LLNGLYDAKLDHVPVVAIVGQQARAALGGHYQQEVDLQSLFKDVaGAFVQMVTVPEQLRHLVDRAVRTALAER-TVTAVI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 162 LPVDVQlaEIEFDPDTYE------------PMPLARPAATRAQAEkalaMLAAAERPLIVAGGGIvnADAAGLLVEFAEL 229
Cdd:PRK08273 161 LPNDVQ--ELEYEPPPHAhgtvhsgvgytrPRVVPYDEDLRRAAE----VLNAGRKVAILVGAGA--LGATDEVIAVAER 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 230 VDVPVVPTLMGWGTIADDHPLMAGMVGLQAAhRYGNATMLEADFVLGIGNRwanrhtgglDTYT---------RGrtfVH 300
Cdd:PRK08273 233 LGAGVAKALLGKAALPDDLPWVTGSIGLLGT-KPSYELMRECDTLLMVGSS---------FPYSeflpkegqaRG---VQ 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 301 VDIEPTQIGRVFAPGYGIVSDAGAALERFVEVARARkaagtlPDRS------EWVAQCRRrkqTLQRRTHFDDVPIKPQR 374
Cdd:PRK08273 300 IDIDGRMLGLRYPMEVNLVGDAAETLRALLPLLERK------KDRSwrerieKWVARWWE---TLEARAMVPADPVNPQR 370
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 375 VYEEMNRAFgPETRYVSA-IGLSQIAAAQFLHVQQARHWINCGQAGPLGWTVPAALGVRVADPEAPVVAISGDYDFQfM- 452
Cdd:PRK08273 371 VFWELSPRL-PDNAILTAdSGSCANWYARDLRMRRGMMASLSGTLATMGPAVPYAIAAKFAHPDRPVIALVGDGAMQ-Mn 448
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 453 -LEELAVGAQF-----NLPYVHVVVNNSYLGLIRQAQRGFDMDycvqlsfeninaPELGAY----GVDHVKVAEGLGCKA 522
Cdd:PRK08273 449 gMAELITVAKYwrqwsDPRLIVLVLNNRDLNQVTWEQRVMEGD------------PKFEASqdlpDVPYARFAELLGLKG 516
|
570 580 590
....*....|....*....|....*....|..
gi 497628394 523 IRVHEPGDLLPAFEKAgnLAAEHqvPVVVEVI 554
Cdd:PRK08273 517 IRVDDPEQLGAAWDEA--LAADR--PVVLEVK 544
|
|
| TPP_enzyme_C |
pfam02775 |
Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; |
392-553 |
7.57e-43 |
|
Thiamine pyrophosphate enzyme, C-terminal TPP binding domain;
Pssm-ID: 460689 [Multi-domain] Cd Length: 151 Bit Score: 150.43 E-value: 7.57e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 392 AIGLSQIAAAQFLHVQQARHWINCGQAGPLGWTVPAALGVRVADPEAPVVAISGDYDFQFMLEELAVGAQFNLPYVHVVV 471
Cdd:pfam02775 1 DIGCHQMWAAQYYRFRPPRRYLTSGGLGTMGYGLPAAIGAKLARPDRPVVAIAGDGGFQMNLQELATAVRYNLPITVVVL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 472 NNSYLGLIRQAQRGFDMDYCVQLSFENINAPelgaygvDHVKVAEGLGCKAIRVHEPGDLLPAFEKagnlAAEHQVPVVV 551
Cdd:pfam02775 81 NNGGYGMTRGQQTPFGGGRYSGPSGKILPPV-------DFAKLAEAYGAKGARVESPEELEEALKE----ALEHDGPALI 149
|
..
gi 497628394 552 EV 553
Cdd:pfam02775 150 DV 151
|
|
| PDC1 |
COG3961 |
TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase [Carbohydrate ... |
1-557 |
5.11e-40 |
|
TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase [Carbohydrate transport and metabolism, Coenzyme transport and metabolism, General function prediction only]; TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase is part of the Pathway/BioSystem: Pyruvate oxidation
Pssm-ID: 443161 [Multi-domain] Cd Length: 545 Bit Score: 153.39 E-value: 5.11e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 1 MPKMTAAAAAVEILKREGVDHAFGVPGAAINPFYAALRARGGIGHTLARHVEGASHMAEGYTRTAPgnIGVCVGTSGPAG 80
Cdd:COG3961 2 PMTYTVGDYLLDRLAELGIRHIFGVPGDYNLPFLDAIEAHPGIRWVGCCNELNAGYAADGYARVNG--LGALVTTYGVGE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 81 TDMITGLYSASADSVPILCITGqAPVAR-------LH----KEDFQAVdiSSIAQPVTKmAVTVLEPAQVPGAFQRAFHL 149
Cdd:COG3961 80 LSAINGIAGAYAERVPVVHIVG-APGTRaqrrgplLHhtlgDGDFDHF--LRMFEEVTV-AQAVLTPENAAAEIDRVLAA 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 150 MRSGRPgPVLIDLPVDVQLAEIEFDPDTYEPMPLAR-PAATRAQAEKALAMLAAAERPLIVAGGGIVNADAAGLLVEFAE 228
Cdd:COG3961 156 ALREKR-PVYIELPRDVADAPIEPPEAPLPLPPPASdPAALAAAVAAAAERLAKAKRPVILAGVEVHRFGLQEELLALAE 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 229 LVDVPVVPTLMGWGTIADDHPLMAGMVGLQAAHRYGNATMLEADFVLGIGNRWAnrhtgglDTYTRGrtFVH-------V 301
Cdd:COG3961 235 KTGIPVATTLLGKSVLDESHPQFIGTYAGAASSPEVREYVENADCVLCLGVVFT-------DTNTGG--FTAqldpertI 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 302 DIEPTQI---GRVFAPgygiVSdAGAALERFVEVARARKAAGTLPDRS--EWVAQcrrrkqtlqrrthfDDVPIKPQRVY 376
Cdd:COG3961 306 DIQPDSVrvgGHIYPG----VS-LADFLEALAELLKKRSAPLPAPAPPppPPPAA--------------PDAPLTQDRLW 366
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 377 EEMNRAFGPETRYVSAIGLSQIAAAqFLHVQQARHWINCGQAGPLGWTVPAALGVRVADPEAPVVAISGDYDFQFMLEEL 456
Cdd:COG3961 367 QRLQAFLDPGDIVVADTGTSLFGAA-DLRLPEGATFIAQPLWGSIGYTLPAALGAALAAPDRRVILLVGDGAFQLTAQEL 445
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 457 AVGAQFNLPYVHVVVNNS-YlgLIRQAqrgfdmdycvqlsfenINAPElGAYGV----DHVKVAEGLGCK---AIRVHEP 528
Cdd:COG3961 446 STMLRYGLKPIIFVLNNDgY--TIERA----------------IHGPD-GPYNDianwDYAKLPEAFGGGnalGFRVTTE 506
|
570 580
....*....|....*....|....*....
gi 497628394 529 GDLLPAFEKAgnlAAEHQVPVVVEVILER 557
Cdd:COG3961 507 GELEEALAAA---EANTDRLTLIEVVLDK 532
|
|
| PRK06546 |
PRK06546 |
pyruvate dehydrogenase; Provisional |
3-554 |
1.17e-39 |
|
pyruvate dehydrogenase; Provisional
Pssm-ID: 180614 [Multi-domain] Cd Length: 578 Bit Score: 152.83 E-value: 1.17e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 3 KMTAAAAAVEILKREGVDHAFGVPGAAINPFYAALRARGGIGHTLARHVEGASHMAEGYTRTApGNIGVCVGTSGPAGTD 82
Cdd:PRK06546 2 AKTVAEQLVEQLVAAGVKRIYGIVGDSLNPIVDAVRRTGGIEWVHVRHEEAAAFAAAAEAQLT-GKLAVCAGSCGPGNLH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 83 MITGLYSASADSVPILCITGQAPVARLHKEDFQAVDISSIAQPVTKMAVTVLEPAQVPGAFQRAF-HLMrsGRPGPVLID 161
Cdd:PRK06546 81 LINGLYDAHRSGAPVLAIASHIPSAQIGSGFFQETHPDRLFVECSGYCEMVSSAEQAPRVLHSAIqHAV--AGGGVSVVT 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 162 LPVDVQLAEIEfDPDTYEPMPLARPAATRAQAE-KALA-MLAAAERPLIVAGGGIVNADAAglLVEFAELVDVPVVPTLM 239
Cdd:PRK06546 159 LPGDIADEPAP-EGFAPSVISPRRPTVVPDPAEvRALAdAINEAKKVTLFAGAGVRGAHAE--VLALAEKIKAPVGHSLR 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 240 GWGTIADDHPLMAGMVGLQAahrYGNAT--MLEADFVLGIGNRWAnrhtggLDTYTRGRTFVHVDIEPTQIGRVFAPGYG 317
Cdd:PRK06546 236 GKEWIQYDNPFDVGMSGLLG---YGAAHeaMHEADLLILLGTDFP------YDQFLPDVRTAQVDIDPEHLGRRTRVDLA 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 318 IVSDAGAALERFVEVARARKaagtlpDRSEWVAQCRRRKQTLQR------RTHFDDVPIKPQRVYEEMNRAFGPETRYVS 391
Cdd:PRK06546 307 VHGDVAETIRALLPLVKEKT------DRRFLDRMLKKHARKLEKvvgaytRKVEKHTPIHPEYVASILDELAADDAVFTV 380
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 392 AIGLSQIAAAQFLHVQQARHWINCGQAGPLGWTVPAALGVRVADPEAPVVAISGDYDFQFMLEELAVGAQFNLPYVHVVV 471
Cdd:PRK06546 381 DTGMCNVWAARYITPNGRRRVIGSFRHGSMANALPHAIGAQLADPGRQVISMSGDGGLSMLLGELLTVKLYDLPVKVVVF 460
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 472 NNSYLGLIRqaqrgFDMDYCVQLSFENINAPelgaygVDHVKVAEGLGCKAIRVHEPGDLLPAFEKAgnLAaeHQVPVVV 551
Cdd:PRK06546 461 NNSTLGMVK-----LEMLVDGLPDFGTDHPP------VDYAAIAAALGIHAVRVEDPKDVRGALREA--FA--HPGPALV 525
|
...
gi 497628394 552 EVI 554
Cdd:PRK06546 526 DVV 528
|
|
| TPP_enzyme_M |
pfam00205 |
Thiamine pyrophosphate enzyme, central domain; The central domain of TPP enzymes contains a ... |
194-328 |
1.44e-39 |
|
Thiamine pyrophosphate enzyme, central domain; The central domain of TPP enzymes contains a 2-fold Rossman fold.
Pssm-ID: 425523 [Multi-domain] Cd Length: 137 Bit Score: 141.16 E-value: 1.44e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 194 EKALAMLAAAERPLIVAGGGIVNADAAGLLVEFAELVDVPVVPTLMGWGTIADDHPLMAGMVGLqAAHRYGNATMLEADF 273
Cdd:pfam00205 2 EKAAELLKKAKRPVILAGGGVRRSGASEELRELAEKLGIPVVTTLMGKGAFPEDHPLYLGMLGM-HGTPAANEALEEADL 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 497628394 274 VLGIGNRWA-NRHTGGLDTYTRGRTFVHVDIEPTQIGRVFAPGYGIVSDAGAALER 328
Cdd:pfam00205 81 VLAVGARFDdIRTTGKLPEFAPDAKIIHIDIDPAEIGKNYPVDVPIVGDAKETLEA 136
|
|
| IolD |
COG3962 |
TPP-dependent trihydroxycyclohexane-1,2-dione (THcHDO) dehydratase, myo-inositol metabolism ... |
48-553 |
1.88e-38 |
|
TPP-dependent trihydroxycyclohexane-1,2-dione (THcHDO) dehydratase, myo-inositol metabolism [Carbohydrate transport and metabolism];
Pssm-ID: 443162 [Multi-domain] Cd Length: 622 Bit Score: 149.89 E-value: 1.88e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 48 ARHVEGASHMAEGYTRTApgN---IGVCVGTSGPAGTDMITGLYSASADSVPILCITG-------QAPVarLHK-EDFQA 116
Cdd:COG3962 63 GRNEQGMAHAAIAYAKQK--NrrrIMACTSSIGPGATNMVTAAALATANRLPVLLLPGdtfatrqPDPV--LQQlEHFHD 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 117 VDISS--IAQPVTKMAVTVLEPAQVPGAFQRAFHLMRSgrP---GPVLIDLPVDVQLAEIEFDPDTYEPM--PLARPAAT 189
Cdd:COG3962 139 PTISVndAFRPVSRYWDRITRPEQLMSALPRAMRVLTD--PaetGAVTLALPQDVQAEAYDYPESFFAKRvhRIRRPPPD 216
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 190 RAQAEKALAMLAAAERPLIVAGGGIVNADAAGLLVEFAELVDVPVVPTLMGWGTIADDHPLMAGMVGL---QAAhrygNA 266
Cdd:COG3962 217 PAELARAVELIRAAKRPLIIAGGGVRYSEATEALRAFAEATGIPVAETQAGKGALPWDHPLNLGGIGVtgtLAA----NA 292
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 267 TMLEADFVLGIGNRWANRHTGGLDTYTR-GRTFVHVDIEPTQIGRVFApgYGIVSDAGAALErfvEVARARKAAGTlpdR 345
Cdd:COG3962 293 LAAEADLVIGVGTRLQDFTTGSKTLFANpDVRFVNINVARFDAYKHDA--LPVVADAREGLE---ALTEALAGWRY---P 364
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 346 SEWVAQCRRRK----QTLQRRTHFDDVPIKPQ-RVYEEMNRAFGPETRYVSAIG--------LSQIAAAQFLHVQQArhw 412
Cdd:COG3962 365 AAWTDEAAELKaewdAEVDRLYAPTNGGLPTQaQVIGAVNEAAGPDDIVVCAAGslpgdlhkLWRTRDPGTYHVEYG--- 441
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 413 INCgqagpLGWTVPAALGVRVADPEAPVVAISGDYDFQFMLEELAVGAQFNLPYVHVVVNNSYLGLIRQAQRGFDMD-YC 491
Cdd:COG3962 442 YSC-----MGYEIAGGLGVKLAEPDREVYVMVGDGSYLMLNSELVTSVQEGKKIIVVLLDNHGFGCINRLQMSTGSQsFG 516
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 497628394 492 VQLSFENINAPEL--GAYGVDHVKVAEGLGCKAIRVHEPGDLLPAFEKagnlAAEHQVPVVVEV 553
Cdd:COG3962 517 TELRDRDTETGRLdgGLLPVDFAANAASLGAKAYRVTTIAELRAALER----AKAADRTTVIVI 576
|
|
| PRK09259 |
PRK09259 |
putative oxalyl-CoA decarboxylase; Validated |
11-538 |
4.87e-38 |
|
putative oxalyl-CoA decarboxylase; Validated
Pssm-ID: 236433 [Multi-domain] Cd Length: 569 Bit Score: 148.21 E-value: 4.87e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 11 VEILKREGVDHAFGVPGAAINPFYAALRARGG--IGHtlaRHVEGASHMA--EGYTRTAPGnigVCVGTSGPAGTDMITG 86
Cdd:PRK09259 17 IDALKLNGIDTIYGVVGIPITDLARLAQAEGIryIGF---RHEQSAGNAAaaAGFLTQKPG---VCLTVSAPGFLNGLTA 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 87 LYSASADSVPILCITGQA--PVARLHKEDFQAVDISSIAQPVTKMAVTVLEPAQVPGAFQRAFHLMRSGRPGPVLIDLPV 164
Cdd:PRK09259 91 LANATTNCFPMIMISGSSerEIVDLQQGDYEELDQLNAAKPFCKAAFRVNRAEDIGIGVARAIRTAVSGRPGGVYLDLPA 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 165 DVQLAEIEFDPDT------YEPMPLARPAatRAQAEKALAMLAAAERPLIVAGGGIVNADAAGLLVEFAELVDVPVVPTL 238
Cdd:PRK09259 171 KVLAQTMDADEALtslvkvVDPAPAQLPA--PEAVDRALDLLKKAKRPLIILGKGAAYAQADEQIREFVEKTGIPFLPMS 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 239 MGWGTIADDHPLMAGmvglqAAHRYgnaTMLEADFVLGIGNR--WANRHtGGLDTYTRGRTFVHVDIEPTQIG---RVFA 313
Cdd:PRK09259 249 MAKGLLPDTHPQSAA-----AARSL---ALANADVVLLVGARlnWLLSH-GKGKTWGADKKFIQIDIEPQEIDsnrPIAA 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 314 PgygIVSDAGAALERFVEvarARKAAGTLPDrSEWVAQCRRRK--------QTLQRRTH---FDDV--PIKpqRVYEEmn 380
Cdd:PRK09259 320 P---VVGDIGSVMQALLA---GLKQNTFKAP-AEWLDALAERKeknaakmaEKLSTDTQpmnFYNAlgAIR--DVLKE-- 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 381 rafGPETRYVSAIGLSQIAAAQFLHVQQARHWINCGQAGPLGWTVPAALGVRVADPEaPVVAISGDYDFQFMLEELAVGA 460
Cdd:PRK09259 389 ---NPDIYLVNEGANTLDLARNIIDMYKPRHRLDCGTWGVMGIGMGYAIAAAVETGK-PVVAIEGDSAFGFSGMEVETIC 464
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 461 QFNLPYVHVVVNNS--YLGLIRQAQRGFDMdycvqlsfeninAPELGAYGVDHVKVAEGLGCKAIRVHEPGDLLPAFEKA 538
Cdd:PRK09259 465 RYNLPVTVVIFNNGgiYRGDDVNLSGAGDP------------SPTVLVHHARYDKMMEAFGGVGYNVTTPDELRHALTEA 532
|
|
| TPP_AHAS |
cd02015 |
Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding ... |
370-563 |
5.54e-37 |
|
Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the acetohydroxyacid, 2-acetolactate. 2-Acetolactate is the precursor of the branched chain amino acids, valine and leucine. AHAS also catalyzes the condensation of pyruvate and 2-ketobutyrate to form 2-aceto-2-hydroxybutyrate in isoleucine biosynthesis. In addition to requiring TPP and a divalent metal ion as cofactors, AHAS requires FAD.
Pssm-ID: 238973 [Multi-domain] Cd Length: 186 Bit Score: 135.70 E-value: 5.54e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 370 IKPQRVYEEMNRAFGPETRYVSAIGLSQIAAAQFLHVQQARHWINCGQAGPLGWTVPAALGVRVADPEAPVVAISGDYDF 449
Cdd:cd02015 1 IKPQEVIKELSELTPGDAIVTTDVGQHQMWAAQYYRFKKPRSWLTSGGLGTMGFGLPAAIGAKVARPDKTVICIDGDGSF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 450 QFMLEELAVGAQFNLPYVHVVVNNSYLGLIRQAQRGFdmdycvqlsFENINAPELGAYGVDHVKVAEGLGCKAIRVHEPG 529
Cdd:cd02015 81 QMNIQELATAAQYNLPVKIVILNNGSLGMVRQWQELF---------YEGRYSHTTLDSNPDFVKLAEAYGIKGLRVEKPE 151
|
170 180 190
....*....|....*....|....*....|....
gi 497628394 530 DLLPAFEKagnlAAEHQVPVVVEVILERVTNISM 563
Cdd:cd02015 152 ELEAALKE----ALASDGPVLLDVLVDPEENVLP 181
|
|
| TPP_enzymes |
cd00568 |
Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic ... |
374-554 |
1.09e-35 |
|
Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and the branched chain alpha-keto acid dehydrogenase complexes.
Pssm-ID: 238318 [Multi-domain] Cd Length: 168 Bit Score: 131.61 E-value: 1.09e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 374 RVYEEMNRAFGPETRYVSAIGLSQIAAAQFLHVQQARHWINCGQAGPLGWTVPAALGVRVADPEAPVVAISGDYDFQFML 453
Cdd:cd00568 1 RVLAALRAALPEDAIVVNDAGNSAYWAYRYLPLRRGRRFLTSTGFGAMGYGLPAAIGAALAAPDRPVVCIAGDGGFMMTG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 454 EELAVGAQFNLPYVHVVVNNSYLGLIRQAQRGFDmdycvqlsfeNINAPELGAYGVDHVKVAEGLGCKAIRVHEPGDLLP 533
Cdd:cd00568 81 QELATAVRYGLPVIVVVFNNGGYGTIRMHQEAFY----------GGRVSGTDLSNPDFAALAEAYGAKGVRVEDPEDLEA 150
|
170 180
....*....|....*....|.
gi 497628394 534 AFEKagnlAAEHQVPVVVEVI 554
Cdd:cd00568 151 ALAE----ALAAGGPALIEVK 167
|
|
| TPP_PYR_POX |
cd07039 |
Pyrimidine (PYR) binding domain of POX; Thiamine pyrophosphate (TPP family), pyrimidine (PYR) ... |
5-170 |
2.37e-34 |
|
Pyrimidine (PYR) binding domain of POX; Thiamine pyrophosphate (TPP family), pyrimidine (PYR) binding domain of pyruvate oxidase (POX) subfamily. The PYR domain is found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. TPP binds in the cleft formed by a PYR domain and a PP domain. The PYR domain, binds the aminopyrimidine ring of TPP, the PP domain binds the diphosphate residue. The PYR and PP domains have a common fold, but do not share strong sequence conservation. The PP domain is not included in this sub-family. Most TPP-dependent enzymes have the PYR and PP domains on the same subunit although these domains can be alternatively arranged in the primary structure. TPP-dependent enzymes are multisubunit proteins, the smallest catalytic unit being a dimer-of-active sites. Lactobacillus plantarum POX is a homotetramer (dimer-of-homodimers), having two active sites per homodimer lying between PYR and PP domains of different subunits. POX decarboxylates pyruvate, producing hydrogen peroxide and the energy-storage metabolite acetylphosphate.
Pssm-ID: 132922 [Multi-domain] Cd Length: 164 Bit Score: 127.67 E-value: 2.37e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 5 TAAAAAVEILKREGVDHAFGVPGAAINPFYAALRARGGIGHTLARHVEGASHMAEGYTRTApGNIGVCVGTSGPAGTDMI 84
Cdd:cd07039 1 TVADVIVETLENWGVKRVYGIPGDSINGLMDALRREGKIEFIQVRHEEAAAFAASAEAKLT-GKLGVCLGSSGPGAIHLL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 85 TGLYSASADSVPILCITGQAPVARLHKEDFQAVDISSIAQPVTKMAVTVLEPAQVPGAFQRAfhlMRS--GRPGPVLIDL 162
Cdd:cd07039 80 NGLYDAKRDRAPVLAIAGQVPTDELGTDYFQEVDLLALFKDVAVYNETVTSPEQLPELLDRA---IRTaiAKRGVAVLIL 156
|
....*...
gi 497628394 163 PVDVQLAE 170
Cdd:cd07039 157 PGDVQDAP 164
|
|
| PRK07092 |
PRK07092 |
benzoylformate decarboxylase; Reviewed |
1-556 |
2.96e-33 |
|
benzoylformate decarboxylase; Reviewed
Pssm-ID: 235931 [Multi-domain] Cd Length: 530 Bit Score: 133.54 E-value: 2.96e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 1 MPKMTAAAAAV--------EILKREGVDHAFGVPGAAINPFYAALRArgGIGHTLARHVEGASHMAEGYTRtAPGNIGVc 72
Cdd:PRK07092 1 MPKATAPAAAMttvrdatiDLLRRFGITTVFGNPGSTELPFLRDFPD--DFRYVLGLQEAVVVGMADGYAQ-ATGNAAF- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 73 VGTSGPAGTDMITG-LYSASADSVPILCITGQAPVARLHKEDF-QAVDISSIAQPVTKMAVtvlEPAQ---VPGAFQRAF 147
Cdd:PRK07092 77 VNLHSAAGVGNAMGnLFTAFKNHTPLVITAGQQARSILPFEPFlAAVQAAELPKPYVKWSI---EPARaedVPAAIARAY 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 148 HLMRSGRPGPVLIDLPVDvqlaeiEFDPDTyEPMPLARPAATRAQAEKALA----MLAAAERPLIVAGGGIVNADAAGLL 223
Cdd:PRK07092 154 HIAMQPPRGPVFVSIPYD------DWDQPA-EPLPARTVSSAVRPDPAALArlgdALDAARRPALVVGPAVDRAGAWDDA 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 224 VEFAELVDVPV-VPTLMGWGTIADDHPLMAGMvgLQAAHRYGNATMLEADFVLGIGNRWANRHTGGLDTYT-RGRTFVHV 301
Cdd:PRK07092 227 VRLAERHRAPVwVAPMSGRCSFPEDHPLFAGF--LPASREKISALLDGHDLVLVIGAPVFTYHVEGPGPHLpEGAELVQL 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 302 DIEPTQIGRvfAP-GYGIVSDAGAALERFVEVAR--ARKAAGTLPDRSEWVAQcrrrkqtlqrrthfdDVPIKPQRVYEE 378
Cdd:PRK07092 305 TDDPGEAAW--APmGDAIVGDIRLALRDLLALLPpsARPAPPARPMPPPAPAP---------------GEPLSVAFVLQT 367
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 379 MNRAFGPETRYVSAIGLSQIAAAQFLHVQQARHWINcGQAGPLGWTVPAALGVRVADPEAPVVAISGDYDFQFMLEELAV 458
Cdd:PRK07092 368 LAALRPADAIVVEEAPSTRPAMQEHLPMRRQGSFYT-MASGGLGYGLPAAVGVALAQPGRRVIGLIGDGSAMYSIQALWS 446
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 459 GAQFNLPYVHVVVNNSYLGLIRQAQRGFDMDycvqlsfeniNAPELGAYGVDHVKVAEGLGCKAIRVHEPGDLLPAFEKA 538
Cdd:PRK07092 447 AAQLKLPVTFVILNNGRYGALRWFAPVFGVR----------DVPGLDLPGLDFVALARGYGCEAVRVSDAAELADALARA 516
|
570
....*....|....*...
gi 497628394 539 gnLAAEHqvPVVVEVILE 556
Cdd:PRK07092 517 --LAADG--PVLVEVEVA 530
|
|
| TPP_POX |
cd02014 |
Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; ... |
369-557 |
5.05e-29 |
|
Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates pyruvate, producing hydrogen peroxide and the energy-storage metabolite acetylphosphate. It requires FAD in addition to TPP and a divalent cation as cofactors.
Pssm-ID: 238972 [Multi-domain] Cd Length: 178 Bit Score: 113.39 E-value: 5.05e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 369 PIKPQRVYEEMNRAFGPETRYVSAIGLSQIAAAQFLHVQQARHWINCGQAGPLGWTVPAALGVRVADPEAPVVAISGDYD 448
Cdd:cd02014 1 PIHPERVAAELNKRAPDDAIFTIDVGNVTVWAARHLRMNGKQRFILSGLLATMGNGLPGAIAAKLAYPDRQVIALSGDGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 449 FQFMLEELAVGAQFNLPYVHVVVNNSYLGLIRQAQRgfDMDYcvqlsfeninaPELGA--YGVDHVKVAEGLGCKAIRVH 526
Cdd:cd02014 81 FAMLMGDLITAVKYNLPVIVVVFNNSDLGFIKWEQE--VMGQ-----------PEFGVdlPNPDFAKIAEAMGIKGIRVE 147
|
170 180 190
....*....|....*....|....*....|.
gi 497628394 527 EPGDLLPAFEKagnlAAEHQVPVVVEVILER 557
Cdd:cd02014 148 DPDELEAALDE----ALAADGPVVIDVVTDP 174
|
|
| TPP_enzyme_PYR |
cd06586 |
Pyrimidine (PYR) binding domain of thiamine pyrophosphate (TPP)-dependent enzymes; Thiamine ... |
8-164 |
1.80e-21 |
|
Pyrimidine (PYR) binding domain of thiamine pyrophosphate (TPP)-dependent enzymes; Thiamine pyrophosphate (TPP) family, pyrimidine (PYR) binding domain; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. TPP binds in the cleft formed by a PYR domain and a PP domain. The PYR domain, binds the aminopyrimidine ring of TPP, the PP domain binds the diphosphate residue. A polar interaction between the conserved glutamate of the PYR domain and the N1' of the TPP aminopyrimidine ring is shared by most TPP-dependent enzymes, and participates in the activation of TPP. The PYR and PP domains have a common fold, but do not share strong sequence conservation. The PP domain is not included in this group. Most TPP-dependent enzymes have the PYR and PP domains on the same subunit although these domains can be alternatively arranged in the primary structure. In the case of 2-oxoisovalerate dehydrogenase (2OXO), sulfopyruvate decarboxylase (ComDE), and the E1 component of human pyruvate dehydrogenase complex (E1- PDHc) the PYR and PP domains appear on different subunits. TPP-dependent enzymes are multisubunit proteins, the smallest catalytic unit being a dimer-of-active sites. For many of these enzymes the active sites lie between PP and PYR domains on different subunits. However, for the homodimeric enzymes 1-deoxy-D-xylulose 5-phosphate synthase (DXS) and Desulfovibrio africanus pyruvate:ferredoxin oxidoreductase (PFOR), each active site lies at the interface of the PYR and PP domains from the same subunit.
Pssm-ID: 132915 [Multi-domain] Cd Length: 154 Bit Score: 91.25 E-value: 1.80e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 8 AAAVEILKREGVDHAFGVPGAAINPFYAALRARGGIGHTLARHVEGASHMAEGYTRTapGNIGVCVGTSGPAGTDMITGL 87
Cdd:cd06586 1 AAFAEVLTAWGVRHVFGYPGDEISSLLDALREGDKRIIDTVIHELGAAGAAAGYARA--GGPPVVIVTSGTGLLNAINGL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 88 YSASADSVPILCITGQAPVARLHKEDFQAVDISSIAQPVTKMAVTVL----EPAQVPGAFQRAFhlmrsGRPGPVLIDLP 163
Cdd:cd06586 79 ADAAAEHLPVVFLIGARGISAQAKQTFQSMFDLGMYRSIPEANISSPspaeLPAGIDHAIRTAY-----ASQGPVVVRLP 153
|
.
gi 497628394 164 V 164
Cdd:cd06586 154 R 154
|
|
| TPP_BZL_OCoD_HPCL |
cd02004 |
Thiamine pyrophosphate (TPP) family, BZL_OCoD_HPCL subfamily, TPP-binding module; composed of ... |
372-556 |
8.31e-21 |
|
Thiamine pyrophosphate (TPP) family, BZL_OCoD_HPCL subfamily, TPP-binding module; composed of proteins similar to benzaldehyde lyase (BZL), oxalyl-CoA decarboxylase (OCoD) and 2-hydroxyphytanoyl-CoA lyase (2-HPCL). Pseudomonas fluorescens biovar I BZL cleaves the acyloin linkage of benzoin producing 2 molecules of benzaldehyde and enabling the Pseudomonas to grow on benzoin as the sole carbon and energy source. OCoD has a role in the detoxification of oxalate, catalyzing the decarboxylation of oxalyl-CoA to formate. 2-HPCL is a peroxisomal enzyme which plays a role in the alpha-oxidation of 3-methyl-branched fatty acids, catalyzing the cleavage of 2-hydroxy-3-methylacyl-CoA into formyl-CoA and a 2-methyl-branched fatty aldehyde. All these enzymes depend on Mg2+ and TPP for activity.
Pssm-ID: 238962 [Multi-domain] Cd Length: 172 Bit Score: 89.90 E-value: 8.31e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 372 PQRVYEEMNRAFGPETRYVSAIGLSQIAAAQFLHVQQARHWINCGQAGPLGWTVPAALGVRVADPEAPVVAISGDYDFQF 451
Cdd:cd02004 1 PYRVLHELQEALPDDAIIVSDGGNTMDWARYILRPRKPRHRLDAGTFGTLGVGLGYAIAAALARPDKRVVLVEGDGAFGF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 452 MLEELAVGAQFNLPYVHVVVNNSYLGLIRQAQrgfdmdycvQLSFENINAPELGAYGVDHVKVAEGLGCKAIRVHEPGDL 531
Cdd:cd02004 81 SGMELETAVRYNLPIVVVVGNNGGWYQGLDGQ---------QLSYGLGLPVTTLLPDTRYDLVAEAFGGKGELVTTPEEL 151
|
170 180
....*....|....*....|....*
gi 497628394 532 LPAFEKagnlAAEHQVPVVVEVILE 556
Cdd:cd02004 152 KPALKR----ALASGKPALINVIID 172
|
|
| TPP_Xsc_like |
cd02013 |
Thiamine pyrophosphate (TPP) family, Xsc-like subfamily, TPP-binding module; composed of ... |
369-557 |
1.30e-18 |
|
Thiamine pyrophosphate (TPP) family, Xsc-like subfamily, TPP-binding module; composed of proteins similar to Alcaligenes defragrans sulfoacetaldehyde acetyltransferase (Xsc). Xsc plays a key role in the degradation of taurine, catalyzing the desulfonation of 2-sulfoacetaldehyde into sulfite and acetyl phosphate. This enzyme requires TPP and divalent metal ions for activity.
Pssm-ID: 238971 [Multi-domain] Cd Length: 196 Bit Score: 84.10 E-value: 1.30e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 369 PIKPQRVYEEMNRAFgPETRYVSA-IGLSQIAAAQFLHVQQARHWINCGQAGPLGWTVPAALGVRVADPEAPVVAISGDY 447
Cdd:cd02013 3 PMHPRQVLRELEKAM-PEDAIVSTdIGNICSVANSYLRFEKPRSFIAPLSFGNCGYALPAIIGAKAAAPDRPVVAIAGDG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 448 DFQFMLEELAVGAQFNLPYVHVVVNNSYLGLIRQAQRGFDMDYCVQLSFENINapelgaygvdHVKVAEGLGCKAIRVHE 527
Cdd:cd02013 82 AWGMSMMEIMTAVRHKLPVTAVVFRNRQWGAEKKNQVDFYNNRFVGTELESES----------FAKIAEACGAKGITVDK 151
|
170 180 190
....*....|....*....|....*....|
gi 497628394 528 PGDLLPAFEKAGNLAAEHQvPVVVEVILER 557
Cdd:cd02013 152 PEDVGPALQKAIAMMAEGK-TTVIEIVCDQ 180
|
|
| TPP_ALS |
cd02010 |
Thiamine pyrophosphate (TPP) family, Acetolactate synthase (ALS) subfamily, TPP-binding module; ... |
372-553 |
8.08e-18 |
|
Thiamine pyrophosphate (TPP) family, Acetolactate synthase (ALS) subfamily, TPP-binding module; composed of proteins similar to Klebsiella pneumoniae ALS, a catabolic enzyme required for butanediol fermentation. ALS catalyzes the conversion of 2 molecules of pyruvate to acetolactate and carbon dioxide. ALS does not contain FAD, and requires TPP and a divalent metal cation for activity.
Pssm-ID: 238968 [Multi-domain] Cd Length: 177 Bit Score: 81.18 E-value: 8.08e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 372 PQRVYEEMNRAFGPETRYVSAIGLSQIAAAQFLHVQQARH-WINCGQAgPLGWTVPAALGVRVADPEAPVVAISGDYDFQ 450
Cdd:cd02010 1 PQRIVHDLRAVMGDDDIVLLDVGAHKIWMARYYRTYAPNTcLISNGLA-TMGVALPGAIGAKLVYPDRKVVAVSGDGGFM 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 451 FMLEELAVGAQFNLPYVHVVVNNSYLGLIRQAQ-----RGFDMDycvqlsFENInapelgaygvDHVKVAEGLGCKAIRV 525
Cdd:cd02010 80 MNSQELETAVRLKIPLVVLIWNDNGYGLIKWKQekeygRDSGVD------FGNP----------DFVKYAESFGAKGYRI 143
|
170 180
....*....|....*....|....*...
gi 497628394 526 HEPGDLLPAFEKAgnLAAEhqVPVVVEV 553
Cdd:cd02010 144 ESADDLLPVLERA--LAAD--GVHVIDC 167
|
|
| TPP_BFDC |
cd02002 |
Thiamine pyrophosphate (TPP) family, BFDC subfamily, TPP-binding module; composed of proteins ... |
402-555 |
3.11e-17 |
|
Thiamine pyrophosphate (TPP) family, BFDC subfamily, TPP-binding module; composed of proteins similar to Pseudomonas putida benzoylformate decarboxylase (BFDC). P. putida BFDC plays a role in the mandelate pathway, catalyzing the conversion of benzoylformate to benzaldehyde and carbon dioxide. This enzyme is dependent on TPP and a divalent metal cation as cofactors.
Pssm-ID: 238960 [Multi-domain] Cd Length: 178 Bit Score: 79.56 E-value: 3.11e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 402 QFLHVQQARHWINCGqAGPLGWTVPAALGVRVADPEAPVVAISGDYDFQFMLEELAVGAQFNLPYVHVVVNNSYLGLIRQ 481
Cdd:cd02002 33 DQLPLTRPGSYFTLR-GGGLGWGLPAAVGAALANPDRKVVAIIGDGSFMYTIQALWTAARYGLPVTVVILNNRGYGALRS 111
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 497628394 482 AQRGFdmdYCVQLSFENINAPELGAYGVDHVKVAEGLGCKAIRVHEPGDLLPAFEKAgnLAAEHqvPVVVEVIL 555
Cdd:cd02002 112 FLKRV---GPEGPGENAPDGLDLLDPGIDFAAIAKAFGVEAERVETPEELDEALREA--LAEGG--PALIEVVV 178
|
|
| TPP_IolD |
cd02003 |
Thiamine pyrophosphate (TPP) family, IolD subfamily, TPP-binding module; composed of proteins ... |
421-572 |
5.54e-14 |
|
Thiamine pyrophosphate (TPP) family, IolD subfamily, TPP-binding module; composed of proteins similar to Rhizobium leguminosarum bv. viciae IolD. IolD plays an important role in myo-inositol catabolism.
Pssm-ID: 238961 [Multi-domain] Cd Length: 205 Bit Score: 71.18 E-value: 5.54e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 421 LGWTVPAALGVRVADPEAPVVAISGDYDFQFMLEELAVGAQFNLPYVHVVVNNSYLGLIRQAQRGfdmdyCVQLSFEN-- 498
Cdd:cd02003 50 MGYEIAAGLGAKLAKPDREVYVLVGDGSYLMLHSEIVTAVQEGLKIIIVLFDNHGFGCINNLQES-----TGSGSFGTef 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 499 ------INAPELGAYGVDHVKVAEGLGCKAIRVHEPGDLLPAFEKagnlAAEHQVPVVVEV-ILERVTNISMGTEID-GV 570
Cdd:cd02003 125 rdrdqeSGQLDGALLPVDFAANARSLGARVEKVKTIEELKAALAK----AKASDRTTVIVIkTDPKSMTPGYGSWWDvGV 200
|
..
gi 497628394 571 AE 572
Cdd:cd02003 201 AE 202
|
|
| TPP_PDC_IPDC |
cd02005 |
Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of ... |
369-557 |
8.79e-13 |
|
Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of pyruvate to acetaldehyde and CO2. It is able to utilize other 2-oxo acids as substrates. In plants and various plant-associated bacteria, IPDC plays a role in the indole-3-pyruvic acid (IPA) pathway, a tryptophan-dependent biosynthetic route to indole-3-acetaldehyde (IAA). IPDC catalyzes the decarboxylation of IPA to IAA. Both PDC and IPDC depend on TPP and Mg2+ as cofactors.
Pssm-ID: 238963 [Multi-domain] Cd Length: 183 Bit Score: 66.79 E-value: 8.79e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 369 PIKPQRVYEEMNRAFGPETRYVSAIGLSQIAAAQFLHVQQARhWINCGQAGPLGWTVPAALGVRVADPEAPVVAISGDYD 448
Cdd:cd02005 1 PLTQARLWQQVQNFLKPNDILVAETGTSWFGALDLKLPKGTR-FISQPLWGSIGYSVPAALGAALAAPDRRVILLVGDGS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 449 FQFMLEELAVGAQFNLPYVHVVVNNsylglirqaqRGFDMDYCVQ---LSFENINapelgayGVDHVKVAEGLGC----K 521
Cdd:cd02005 80 FQMTVQELSTMIRYGLNPIIFLINN----------DGYTIERAIHgpeASYNDIA-------NWNYTKLPEVFGGggggL 142
|
170 180 190
....*....|....*....|....*....|....*.
gi 497628394 522 AIRVHEPGDLLPAFEKAgnlAAEHQVPVVVEVILER 557
Cdd:cd02005 143 SFRVKTEGELDEALKDA---LFNRDKLSLIEVILPK 175
|
|
| PRK12474 |
PRK12474 |
hypothetical protein; Provisional |
1-202 |
9.84e-09 |
|
hypothetical protein; Provisional
Pssm-ID: 139002 [Multi-domain] Cd Length: 518 Bit Score: 57.96 E-value: 9.84e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 1 MPKMTAAAAAVEILKREGVDHAFGVPGAAINPFYAALRARGGIGHTLARHVEGASHMAEGYTRTApGNIGVCVGTSGPAG 80
Cdd:PRK12474 2 GQTMNGADSVVDTLLNCGVEVCFANPGTSEMHFVAALDRVPRMRPVLCLFEGVVTGAADGYGRIA-GKPAVTLLHLGPGL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 81 TDMITGLYSASADSVPILCITGQAPVARLHKEDFQAVDISSIAQPVTKMAVTVLEPAQVPGAFQRAFHLMRSGRPGPVLI 160
Cdd:PRK12474 81 ANGLANLHNARRAASPIVNIVGDHAVEHLQYDAPLTSDIDGFARPVSRWVHRSASAGAVDSDVARAVQAAQSAPGGIATL 160
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 497628394 161 DLPVDVQlaeieFDPDTYEPMPLARPAATRAQAEKALAMLAA 202
Cdd:PRK12474 161 IMPADVA-----WNEAAYAAQPLRGIGPAPVAAETVERIAAL 197
|
|
| TPP_PYR_MenD |
cd07037 |
Pyrimidine (PYR) binding domain of ... |
8-163 |
1.33e-06 |
|
Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1-carboxylate synthase (MenD) and related proteins; Thiamine pyrophosphate (TPP family), pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1-carboxylate (SEPHCHC) synthase (MenD) subfamily. The PYR domain is found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. TPP binds in the cleft formed by a PYR domain and a PP domain. The PYR domain, binds the aminopyrimidine ring of TPP, the PP domain binds the diphosphate residue. The PYR and PP domains have a common fold, but do not share strong sequence conservation. The PP domain is not included in this sub-family. Most TPP-dependent enzymes have the PYR and PP domains on the same subunit although these domains can be alternatively arranged in the primary structure. TPP-dependent enzymes are multisubunit proteins, the smallest catalytic unit being a dimer-of-active sites. Escherichia coli MenD (EcMenD) is a homotetramer (dimer-of-homodimers), having two active sites per homodimer lying between PYR and PP domains of different subunits. EcMenD catalyzes a Stetter-like conjugate addition of alpha-ketoglutarate to isochorismate, leading to the formation of SEPHCHC and carbon dioxide, this addition is the first committed step in the biosynthesis of vitamin K2 (menaquinone).
Pssm-ID: 132920 [Multi-domain] Cd Length: 162 Bit Score: 48.65 E-value: 1.33e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 8 AAAVEILKREGVDHAFGVPGAAINPFYAALRARGGIghTLARHVE--GASHMAEGYTRTApGNIGVCVGTSGPAGTDMIT 85
Cdd:cd07037 1 QALVEELKRLGVRDVVISPGSRSAPLALAAAEHPEF--RLHVRVDerSAAFFALGLAKAS-GRPVAVVCTSGTAVANLLP 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 86 GLYSASADSVPILCITGQAPVARLHKEDFQAVDISSIAQPVTKMAVTVLEPAQVPG------AFQRAFHLMRSGRPGPVL 159
Cdd:cd07037 78 AVVEAYYSGVPLLVLTADRPPELRGTGANQTIDQVGLFGDYVRWSVDLPPPEDDDDlwyllrLANRAVLEALSAPPGPVH 157
|
....
gi 497628394 160 IDLP 163
Cdd:cd07037 158 LNLP 161
|
|
| TPP_PYR_PDC_IPDC_like |
cd07038 |
Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase ... |
11-164 |
2.15e-06 |
|
Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Thiamine pyrophosphate (TPP family), pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC) subfamily. The PYR domain is found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. TPP binds in the cleft formed by a PYR domain and a PP domain. The PYR domain, binds the aminopyrimidine ring of TPP, the PP domain binds the diphosphate residue. The PYR and PP domains have a common fold, but do not share strong sequence conservation. The PP domain is not included in this sub-family. Most TPP-dependent enzymes have the PYR and PP domains on the same subunit although these domains can be alternatively arranged in the primary structure. TPP-dependent enzymes are multisubunit proteins, the smallest catalytic unit being a dimer-of-active sites, for many the active sites lie between PP and PYR domains on different subunits. PDC catalyzes the conversion of pyruvate to acetaldehyde and CO2 in alcoholic fermentation. IPDC plays a role in the indole-3-pyruvic acid (IPA) pathway in plants and various plant-associated bacteria, it catalyzes the decarboxylation of IPA to IAA. Also belonging to this group is Mycobacterium tuberculosis alpha-keto acid decarboxylase (MtKDC) which participates in amino acid degradation via the Ehrlich pathway, and Lactococcus lactis branched-chain keto acid decarboxylase (KdcA) an enzyme identified as being involved in cheese ripening, which exhibits a very broad substrate range in the decarboxylation and carboligation reactions.
Pssm-ID: 132921 [Multi-domain] Cd Length: 162 Bit Score: 47.87 E-value: 2.15e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 11 VEILKREGVDHAFGVPGAAINPFYAALRARGGIGHTLARHVEGASHMAEGYTRTAPgnIGVCVGTSGPAGTDMITGLYSA 90
Cdd:cd07038 4 LERLKQLGVKHVFGVPGDYNLPLLDAIEENPGLRWVGNCNELNAGYAADGYARVKG--LGALVTTYGVGELSALNGIAGA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 91 SADSVPILCITGQAPV------ARLH----KEDFQAvdISSIAQPVTkMAVTVLEPAQVPGA-FQRAF-HLMRSGRpgPV 158
Cdd:cd07038 82 YAEHVPVVHIVGAPSTkaqasgLLLHhtlgDGDFDV--FLKMFEEIT-CAAARLTDPENAAEeIDRVLrTALRESR--PV 156
|
....*.
gi 497628394 159 LIDLPV 164
Cdd:cd07038 157 YIEIPR 162
|
|
| PRK07586 |
PRK07586 |
acetolactate synthase large subunit; |
4-219 |
2.81e-06 |
|
acetolactate synthase large subunit;
Pssm-ID: 236063 [Multi-domain] Cd Length: 514 Bit Score: 50.23 E-value: 2.81e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 4 MTAAAAAVEILKREGVDHAFGVPGAAINPFYAALRARGGIGHTLARHVEGASHMAEGYTRTApgnigvcvGTsgPAGTDM 83
Cdd:PRK07586 1 MNGAESLVRTLVDGGVDVCFANPGTSEMHFVAALDRVPGMRCVLGLFEGVATGAADGYARMA--------GK--PAATLL 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497628394 84 ITG---------LYSASADSVPILCITGQApvARLHKeDFQA---VDISSIAQPVTKMAVTVLEPAQVPGAFQRAFHLMR 151
Cdd:PRK07586 71 HLGpglanglanLHNARRARTPIVNIVGDH--ATYHR-KYDApltSDIEALARPVSGWVRRSESAADVAADAAAAVAAAR 147
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 497628394 152 SGRPGPVLIDLPVDVQLAEIefDPDTYEPMPLARPAATRAQAEKALAMLAAAERPLIVAGGGIVNADA 219
Cdd:PRK07586 148 GAPGQVATLILPADVAWSEG--GPPAPPPPAPAPAAVDPAAVEAAAAALRSGEPTVLLLGGRALRERG 213
|
|
| PRK06546 |
PRK06546 |
pyruvate dehydrogenase; Provisional |
110-165 |
9.84e-03 |
|
pyruvate dehydrogenase; Provisional
Pssm-ID: 180614 [Multi-domain] Cd Length: 578 Bit Score: 38.82 E-value: 9.84e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 497628394 110 HKEDFQAVDISSIAQPVTKMAVTVLEPAQVPGAFQRAFHlmrsgRPGPVLIDLPVD 165
Cdd:PRK06546 480 FGTDHPPVDYAAIAAALGIHAVRVEDPKDVRGALREAFA-----HPGPALVDVVTD 530
|
|
| |
