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Conserved domains on  [gi|491246674|ref|WP_005104873|]
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DNA circularization protein [Shigella flexneri]

Protein Classification

DNA circularization protein( domain architecture ID 10008371)

DNA circularization protein similar to Escherichia virus Mu DNA circularization protein N (gpN) that is required for tail assembly of phage Mu and is responsible for circularizing the viral DNA after it has been ejected into the host cell

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
COG4228 COG4228
Mu-like prophage DNA circulation protein [Mobilome: prophages, transposons];
2-442 4.96e-109

Mu-like prophage DNA circulation protein [Mobilome: prophages, transposons];


:

Pssm-ID: 443372 [Multi-domain]  Cd Length: 406  Bit Score: 327.79  E-value: 4.96e-109
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491246674   2 TWKDRLQDASFRGVPFKVEEESAGTGRRVETHEYPNRDKPYTEDLGKITFRPSITAYVVGDDCFDQRDRLIDALNKPGPG 81
Cdd:COG4228    3 SWRDKLQPASFRGVPFDVESADDSGGRRVAVHEYPYRDGPDVEDLGRKAREIRITAVVIGDDYLAQRDALLDALEQPGPG 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491246674  82 TLVHPTYGELKVCVdGEVRVSTSKSEGRIVRFDLKFVEAGELSYPTSGAATAQTLMSSCSALDDCISDSFSG-FSIDGVA 160
Cdd:COG4228   83 ELVHPYFGSLQVQV-GEYSVRHSAEEGGYATFDLTFVEAGEGAFPAALPDTQDALLAAADAALDAAGADFAAaFSVLAVA 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491246674 161 DFVQNDVVGNASTMLGYVSDAMkvvdsAVSDAARLLQGDI-SVLLPPPSSGKNFVEQVQKMWRTGKRLYGNASDLVTMIK 239
Cdd:COG4228  162 DGALADVLALAGALSGLVGALS-----RLAGPAAGLKSSLtDLLAAPAALAAALTGLVDGLASLASSPADAIGALRSLSA 236
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491246674 240 TLSGVSLGSDLQPRGVWKTDSKTTATATQQRNMVASTLRTTAISEAAYAVTRLPAPTTsavmqnaavgqattpaqstgwp 319
Cdd:COG4228  237 GLSSDWDGNPAASPVPTPSATPSRPAAAQNQAAVAALVRRAALAELARAAAELLEAET---------------------- 294
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491246674 320 svthpalnnapavknTVDLPTWEELTDIRDTLNTAIDKELSRT---TSDALFLALRRVKADLNADINTRLEQSARIIQRT 396
Cdd:COG4228  295 ---------------ETQVLSPDDAQAVRDALQAALDAERADAadaGDDAVYEALRDLRLALLQDLAARAAALPPLVTRT 359
                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*..
gi 491246674 397 PDEVLPALVLAATWFDNAARDADIIRRNAITHPGFVPV-IPLKVPVQ 442
Cdd:COG4228  360 VPATLPALVLAHRLYGDAARADELVRRNGIRHPGFVPGgDLLEVLAR 406
 
Name Accession Description Interval E-value
COG4228 COG4228
Mu-like prophage DNA circulation protein [Mobilome: prophages, transposons];
2-442 4.96e-109

Mu-like prophage DNA circulation protein [Mobilome: prophages, transposons];


Pssm-ID: 443372 [Multi-domain]  Cd Length: 406  Bit Score: 327.79  E-value: 4.96e-109
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491246674   2 TWKDRLQDASFRGVPFKVEEESAGTGRRVETHEYPNRDKPYTEDLGKITFRPSITAYVVGDDCFDQRDRLIDALNKPGPG 81
Cdd:COG4228    3 SWRDKLQPASFRGVPFDVESADDSGGRRVAVHEYPYRDGPDVEDLGRKAREIRITAVVIGDDYLAQRDALLDALEQPGPG 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491246674  82 TLVHPTYGELKVCVdGEVRVSTSKSEGRIVRFDLKFVEAGELSYPTSGAATAQTLMSSCSALDDCISDSFSG-FSIDGVA 160
Cdd:COG4228   83 ELVHPYFGSLQVQV-GEYSVRHSAEEGGYATFDLTFVEAGEGAFPAALPDTQDALLAAADAALDAAGADFAAaFSVLAVA 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491246674 161 DFVQNDVVGNASTMLGYVSDAMkvvdsAVSDAARLLQGDI-SVLLPPPSSGKNFVEQVQKMWRTGKRLYGNASDLVTMIK 239
Cdd:COG4228  162 DGALADVLALAGALSGLVGALS-----RLAGPAAGLKSSLtDLLAAPAALAAALTGLVDGLASLASSPADAIGALRSLSA 236
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491246674 240 TLSGVSLGSDLQPRGVWKTDSKTTATATQQRNMVASTLRTTAISEAAYAVTRLPAPTTsavmqnaavgqattpaqstgwp 319
Cdd:COG4228  237 GLSSDWDGNPAASPVPTPSATPSRPAAAQNQAAVAALVRRAALAELARAAAELLEAET---------------------- 294
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491246674 320 svthpalnnapavknTVDLPTWEELTDIRDTLNTAIDKELSRT---TSDALFLALRRVKADLNADINTRLEQSARIIQRT 396
Cdd:COG4228  295 ---------------ETQVLSPDDAQAVRDALQAALDAERADAadaGDDAVYEALRDLRLALLQDLAARAAALPPLVTRT 359
                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*..
gi 491246674 397 PDEVLPALVLAATWFDNAARDADIIRRNAITHPGFVPV-IPLKVPVQ 442
Cdd:COG4228  360 VPATLPALVLAHRLYGDAARADELVRRNGIRHPGFVPGgDLLEVLAR 406
DNA_circ_N pfam07157
DNA circularization protein N-terminus; This family represents the N-terminus (approximately ...
7-93 7.10e-44

DNA circularization protein N-terminus; This family represents the N-terminus (approximately 100 residues) of a number of phage DNA circularization proteins.


Pssm-ID: 462105  Cd Length: 88  Bit Score: 148.53  E-value: 7.10e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491246674    7 LQDASFRGVPFKVEEESAGTGRRVETHEYPNRDKPYTEDLGKITFRPSITAYVVGDDCFDQRDRLIDALNKPGPGTLVHP 86
Cdd:pfam07157   2 LLDASFRGVPFEVEEADDSGGRRLAVHEYPYRDGPDVEDMGRKARRIRVQAYFVGDDYLDQRDALIDALEKPGPGELVHP 81

                  ....*..
gi 491246674   87 TYGELKV 93
Cdd:pfam07157  82 WLGSMTV 88
 
Name Accession Description Interval E-value
COG4228 COG4228
Mu-like prophage DNA circulation protein [Mobilome: prophages, transposons];
2-442 4.96e-109

Mu-like prophage DNA circulation protein [Mobilome: prophages, transposons];


Pssm-ID: 443372 [Multi-domain]  Cd Length: 406  Bit Score: 327.79  E-value: 4.96e-109
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491246674   2 TWKDRLQDASFRGVPFKVEEESAGTGRRVETHEYPNRDKPYTEDLGKITFRPSITAYVVGDDCFDQRDRLIDALNKPGPG 81
Cdd:COG4228    3 SWRDKLQPASFRGVPFDVESADDSGGRRVAVHEYPYRDGPDVEDLGRKAREIRITAVVIGDDYLAQRDALLDALEQPGPG 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491246674  82 TLVHPTYGELKVCVdGEVRVSTSKSEGRIVRFDLKFVEAGELSYPTSGAATAQTLMSSCSALDDCISDSFSG-FSIDGVA 160
Cdd:COG4228   83 ELVHPYFGSLQVQV-GEYSVRHSAEEGGYATFDLTFVEAGEGAFPAALPDTQDALLAAADAALDAAGADFAAaFSVLAVA 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491246674 161 DFVQNDVVGNASTMLGYVSDAMkvvdsAVSDAARLLQGDI-SVLLPPPSSGKNFVEQVQKMWRTGKRLYGNASDLVTMIK 239
Cdd:COG4228  162 DGALADVLALAGALSGLVGALS-----RLAGPAAGLKSSLtDLLAAPAALAAALTGLVDGLASLASSPADAIGALRSLSA 236
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491246674 240 TLSGVSLGSDLQPRGVWKTDSKTTATATQQRNMVASTLRTTAISEAAYAVTRLPAPTTsavmqnaavgqattpaqstgwp 319
Cdd:COG4228  237 GLSSDWDGNPAASPVPTPSATPSRPAAAQNQAAVAALVRRAALAELARAAAELLEAET---------------------- 294
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491246674 320 svthpalnnapavknTVDLPTWEELTDIRDTLNTAIDKELSRT---TSDALFLALRRVKADLNADINTRLEQSARIIQRT 396
Cdd:COG4228  295 ---------------ETQVLSPDDAQAVRDALQAALDAERADAadaGDDAVYEALRDLRLALLQDLAARAAALPPLVTRT 359
                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*..
gi 491246674 397 PDEVLPALVLAATWFDNAARDADIIRRNAITHPGFVPV-IPLKVPVQ 442
Cdd:COG4228  360 VPATLPALVLAHRLYGDAARADELVRRNGIRHPGFVPGgDLLEVLAR 406
DNA_circ_N pfam07157
DNA circularization protein N-terminus; This family represents the N-terminus (approximately ...
7-93 7.10e-44

DNA circularization protein N-terminus; This family represents the N-terminus (approximately 100 residues) of a number of phage DNA circularization proteins.


Pssm-ID: 462105  Cd Length: 88  Bit Score: 148.53  E-value: 7.10e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491246674    7 LQDASFRGVPFKVEEESAGTGRRVETHEYPNRDKPYTEDLGKITFRPSITAYVVGDDCFDQRDRLIDALNKPGPGTLVHP 86
Cdd:pfam07157   2 LLDASFRGVPFEVEEADDSGGRRLAVHEYPYRDGPDVEDMGRKARRIRVQAYFVGDDYLDQRDALIDALEKPGPGELVHP 81

                  ....*..
gi 491246674   87 TYGELKV 93
Cdd:pfam07157  82 WLGSMTV 88
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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