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Conserved domains on  [gi|491074642|ref|WP_004936264|]
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MULTISPECIES: cytochrome c maturation protein CcmE [Serratia]

Protein Classification

cytochrome c maturation protein CcmE( domain architecture ID 10014127)

cytochrome c maturation protein CcmE acts as a heme chaperone required for the biogenesis of c-type cytochromes

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK13165 PRK13165
cytochrome c maturation protein CcmE;
1-160 1.37e-108

cytochrome c maturation protein CcmE;


:

Pssm-ID: 183874  Cd Length: 160  Bit Score: 306.15  E-value: 1.37e-108
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491074642   1 MNPRRKSRLYLAIVVLIGIALTATLMLYALRSNIDLFYTPGEILQGKGENHEKPEVGQRLRIGGMVMPGSVKRDPNTLQV 80
Cdd:PRK13165   1 MNPRRKKRLWLACAVLAGLALTIGLVLYALRSNIDLFYTPGEILYGKRETQQKPEVGQRLRVGGMVMPGSVQRDPNSLKV 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491074642  81 SFKIYDARGAIGVTYTGILPDLFREGQGVVAQGVLGEGNVVNAREVLAKHDEKYTPPEVADAMKENHKGPAEAYNAPQAE 160
Cdd:PRK13165  81 SFTLYDAGGSVTVTYEGILPDLFREGQGIVAQGVLEEGNHIEAKEVLAKHDENYTPPEVEEAMKKNHRRPAYSYKDKAST 160
 
Name Accession Description Interval E-value
PRK13165 PRK13165
cytochrome c maturation protein CcmE;
1-160 1.37e-108

cytochrome c maturation protein CcmE;


Pssm-ID: 183874  Cd Length: 160  Bit Score: 306.15  E-value: 1.37e-108
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491074642   1 MNPRRKSRLYLAIVVLIGIALTATLMLYALRSNIDLFYTPGEILQGKGENHEKPEVGQRLRIGGMVMPGSVKRDPNTLQV 80
Cdd:PRK13165   1 MNPRRKKRLWLACAVLAGLALTIGLVLYALRSNIDLFYTPGEILYGKRETQQKPEVGQRLRVGGMVMPGSVQRDPNSLKV 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491074642  81 SFKIYDARGAIGVTYTGILPDLFREGQGVVAQGVLGEGNVVNAREVLAKHDEKYTPPEVADAMKENHKGPAEAYNAPQAE 160
Cdd:PRK13165  81 SFTLYDAGGSVTVTYEGILPDLFREGQGIVAQGVLEEGNHIEAKEVLAKHDENYTPPEVEEAMKKNHRRPAYSYKDKAST 160
CcmE COG2332
Cytochrome c biogenesis protein CcmE [Energy production and conversion, Posttranslational ...
1-153 9.51e-79

Cytochrome c biogenesis protein CcmE [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441903  Cd Length: 148  Bit Score: 230.10  E-value: 9.51e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491074642   1 MNPRRKSRLYLAIVVLIGIALTATLMLYALRSNIDLFYTPGEILQGKgenhekPEVGQRLRIGGMVMPGSVKRDPNTLQV 80
Cdd:COG2332    1 MTPRRKKRLKLVVAGLVALGAAVALVLYALRDNIVYFYTPSEVAAGK------APPGRRIRVGGLVVPGSVQRDPDGLTV 74
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 491074642  81 SFKIYDARGAIGVTYTGILPDLFREGQGVVAQGVLGEGNVVNAREVLAKHDEKYTPPEVADAMKENHKGPAEA 153
Cdd:COG2332   75 RFVVTDGGATVPVRYTGILPDLFREGQGVVAEGRLDPDGVFEADEVLAKHDENYMPPEVADALKKAGVWQGGA 147
CcmE pfam03100
CcmE; CcmE is the product of one of a cluster of Ccm genes that are necessary for cytochrome c ...
4-137 1.76e-63

CcmE; CcmE is the product of one of a cluster of Ccm genes that are necessary for cytochrome c biosynthesis in eubacteria. Expression of these proteins is induced when the organizms are grown under anaerobic conditions with nitrate or nitrite as the final electron acceptor.


Pssm-ID: 460805  Cd Length: 129  Bit Score: 190.78  E-value: 1.76e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491074642    4 RRKSRLYLAIVVLIGIALTATLMLYALRSNIDLFYTPGEILQGKGenhekPEVGQRLRIGGMVMPGSVKRDPNTLQVSFK 83
Cdd:pfam03100   1 RRKRRLKLLLAGLVALGAAVYLVLSALRDNIVYFLTPSEVLAGPA-----PLAGRRIRLGGLVVPGSVKRDPDGLTVRFV 75
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 491074642   84 IYDARGAIGVTYTGILPDLFREGQGVVAQGVLGEGNVVNAREVLAKHDEKYTPP 137
Cdd:pfam03100  76 VTDGGATLPVVYTGILPDLFREGQGVVVEGRLGPDGVFVADEVLAKHDEKYMPP 129
 
Name Accession Description Interval E-value
PRK13165 PRK13165
cytochrome c maturation protein CcmE;
1-160 1.37e-108

cytochrome c maturation protein CcmE;


Pssm-ID: 183874  Cd Length: 160  Bit Score: 306.15  E-value: 1.37e-108
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491074642   1 MNPRRKSRLYLAIVVLIGIALTATLMLYALRSNIDLFYTPGEILQGKGENHEKPEVGQRLRIGGMVMPGSVKRDPNTLQV 80
Cdd:PRK13165   1 MNPRRKKRLWLACAVLAGLALTIGLVLYALRSNIDLFYTPGEILYGKRETQQKPEVGQRLRVGGMVMPGSVQRDPNSLKV 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491074642  81 SFKIYDARGAIGVTYTGILPDLFREGQGVVAQGVLGEGNVVNAREVLAKHDEKYTPPEVADAMKENHKGPAEAYNAPQAE 160
Cdd:PRK13165  81 SFTLYDAGGSVTVTYEGILPDLFREGQGIVAQGVLEEGNHIEAKEVLAKHDENYTPPEVEEAMKKNHRRPAYSYKDKAST 160
PRK13150 PRK13150
cytochrome c maturation protein CcmE;
1-154 8.58e-90

cytochrome c maturation protein CcmE;


Pssm-ID: 139376  Cd Length: 159  Bit Score: 258.77  E-value: 8.58e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491074642   1 MNPRRKSRLYLAIVVLIGIALTATLMLYALRSNIDLFYTPGEILQGKGENHEKPEVGQRLRIGGMVMPGSVKRDPNTLQV 80
Cdd:PRK13150   1 MNLRRKNRLWVVCAVLAGLGLTTALVLYALRANIDLFYTPGEILYGKRETQQLPAVGQRLRVGGMVMPGSVRRDPDSLKV 80
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 491074642  81 SFKIYDARGAIGVTYTGILPDLFREGQGVVAQGVLGEGNVVNAREVLAKHDEKYTPPEVADAMKENHKGPAEAY 154
Cdd:PRK13150  81 NFSLYDAEGSVTVSYEGILPDLFREGQGVVVQGTLEKGNHVLAHEVLAKHDENYTPPEVEKAMQENHRRPQRAD 154
CcmE COG2332
Cytochrome c biogenesis protein CcmE [Energy production and conversion, Posttranslational ...
1-153 9.51e-79

Cytochrome c biogenesis protein CcmE [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441903  Cd Length: 148  Bit Score: 230.10  E-value: 9.51e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491074642   1 MNPRRKSRLYLAIVVLIGIALTATLMLYALRSNIDLFYTPGEILQGKgenhekPEVGQRLRIGGMVMPGSVKRDPNTLQV 80
Cdd:COG2332    1 MTPRRKKRLKLVVAGLVALGAAVALVLYALRDNIVYFYTPSEVAAGK------APPGRRIRVGGLVVPGSVQRDPDGLTV 74
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 491074642  81 SFKIYDARGAIGVTYTGILPDLFREGQGVVAQGVLGEGNVVNAREVLAKHDEKYTPPEVADAMKENHKGPAEA 153
Cdd:COG2332   75 RFVVTDGGATVPVRYTGILPDLFREGQGVVAEGRLDPDGVFEADEVLAKHDENYMPPEVADALKKAGVWQGGA 147
PRK13254 PRK13254
cytochrome c maturation protein CcmE;
1-148 2.30e-64

cytochrome c maturation protein CcmE;


Pssm-ID: 237317  Cd Length: 148  Bit Score: 193.93  E-value: 2.30e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491074642   1 MNPRRKSRLYLAIVVLIGIALTATLMLYALRSNIDLFYTPGEILQGKgenhekPEVGQRLRIGGMVMPGSVKRDpNTLQV 80
Cdd:PRK13254   1 MMKRKRRRLLIILGALAALGLAVALVLYALRQNIVFFYTPSEVAEGE------APAGRRFRLGGLVEKGSVQRG-DGLTV 73
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 491074642  81 SFKIYDARGAIGVTYTGILPDLFREGQGVVAQGVLGEGNVVNAREVLAKHDEKYTPPEVADAMKENHK 148
Cdd:PRK13254  74 RFVVTDGNATVPVVYTGILPDLFREGQGVVAEGRLQDGGVFVADEVLAKHDENYMPKEVADALKKAGV 141
CcmE pfam03100
CcmE; CcmE is the product of one of a cluster of Ccm genes that are necessary for cytochrome c ...
4-137 1.76e-63

CcmE; CcmE is the product of one of a cluster of Ccm genes that are necessary for cytochrome c biosynthesis in eubacteria. Expression of these proteins is induced when the organizms are grown under anaerobic conditions with nitrate or nitrite as the final electron acceptor.


Pssm-ID: 460805  Cd Length: 129  Bit Score: 190.78  E-value: 1.76e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491074642    4 RRKSRLYLAIVVLIGIALTATLMLYALRSNIDLFYTPGEILQGKGenhekPEVGQRLRIGGMVMPGSVKRDPNTLQVSFK 83
Cdd:pfam03100   1 RRKRRLKLLLAGLVALGAAVYLVLSALRDNIVYFLTPSEVLAGPA-----PLAGRRIRLGGLVVPGSVKRDPDGLTVRFV 75
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 491074642   84 IYDARGAIGVTYTGILPDLFREGQGVVAQGVLGEGNVVNAREVLAKHDEKYTPP 137
Cdd:pfam03100  76 VTDGGATLPVVYTGILPDLFREGQGVVVEGRLGPDGVFVADEVLAKHDEKYMPP 129
PRK13159 PRK13159
cytochrome c-type biogenesis protein CcmE; Reviewed
1-157 1.05e-44

cytochrome c-type biogenesis protein CcmE; Reviewed


Pssm-ID: 183873  Cd Length: 155  Bit Score: 144.37  E-value: 1.05e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491074642   1 MNPRRKSRLYLAIVVLIGIALTATLMLYALRSNIDLFYTPGEILQGKGENHekpevgQRLRIGGMVMPGSVKRDPNTLQV 80
Cdd:PRK13159   1 MNATRKQRLWLVIGVLTAAALAVTLIVLALQRNMSYLFTPSQVRAGAAAGY------QQFRLGGMVKAGSIQRAADSLKV 74
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 491074642  81 SFKIYDARGAIGVTYTGILPDLFREGQGVVAQGVLGEGNVVnAREVLAKHDEKYTPPEVADAMKENHKG-PAEAYNAP 157
Cdd:PRK13159  75 SFTVIDKNAATQVEYTGILPDLFRDNQSVIANGRMQGGRFV-ANEVLAKHDETYMPKELKDAMAEGHLGkPIPAAAAP 151
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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