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Conserved domains on  [gi|490728483|ref|WP_004590886|]
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DUF4864 domain-containing protein [Haloarcula japonica]

Protein Classification

DUF4864 domain-containing protein( domain architecture ID 583910)

DUF4864 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF4864 super family cl24664
Domain of unknown function (DUF4864); This family consists of uncharacterized proteins around ...
 91-197 2.75e-09

Domain of unknown function (DUF4864); This family consists of uncharacterized proteins around 120 residues in length and is mainly found in various Anabaena and Nostoc species. Distant homology analysis suggests this family is related to NTF2-like proteins and specifically to proteins that bind small molecules. HMM partly overlaps with Tol_Tol_Ttg2 (PF05494) involved in Toluene tolerance and lumazine binding family (PF12870) and these families should form a clan.


The actual alignment was detected with superfamily member pfam16156:

Pssm-ID: 435176  Cd Length: 101  Bit Score: 52.33  E-value: 2.75e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490728483   91 VVHIQVLALQNNDPATNeginttWQFASPSNRDLTGPYSNFVRTIQSGFEPLLNATGVRYGPLDRDGDTASQPVTVVNEN 170
Cdd:pfam16156   4 VIGSQLAAFRQDDAATA------FEFASPGIQRLFGTPERFLQMVRQGYPPVYRPRSVAFGKRRDIGGGIVQRVRVVDSD 77

                          90       100
                  ....*....|....*....|....*..
gi 490728483  171 GTttsyRWTVEKQTEGRYEGCWMTAGV 197
Cdd:pfam16156  78 GK----AWTAEYQMIRQPDGSWRINGV 100
 
Name Accession Description Interval E-value
DUF4864 pfam16156
Domain of unknown function (DUF4864); This family consists of uncharacterized proteins around ...
 91-197 2.75e-09

Domain of unknown function (DUF4864); This family consists of uncharacterized proteins around 120 residues in length and is mainly found in various Anabaena and Nostoc species. Distant homology analysis suggests this family is related to NTF2-like proteins and specifically to proteins that bind small molecules. HMM partly overlaps with Tol_Tol_Ttg2 (PF05494) involved in Toluene tolerance and lumazine binding family (PF12870) and these families should form a clan.


Pssm-ID: 435176  Cd Length: 101  Bit Score: 52.33  E-value: 2.75e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490728483   91 VVHIQVLALQNNDPATNeginttWQFASPSNRDLTGPYSNFVRTIQSGFEPLLNATGVRYGPLDRDGDTASQPVTVVNEN 170
Cdd:pfam16156   4 VIGSQLAAFRQDDAATA------FEFASPGIQRLFGTPERFLQMVRQGYPPVYRPRSVAFGKRRDIGGGIVQRVRVVDSD 77

                          90       100
                  ....*....|....*....|....*..
gi 490728483  171 GTttsyRWTVEKQTEGRYEGCWMTAGV 197
Cdd:pfam16156  78 GK----AWTAEYQMIRQPDGSWRINGV 100
 
Name Accession Description Interval E-value
DUF4864 pfam16156
Domain of unknown function (DUF4864); This family consists of uncharacterized proteins around ...
 91-197 2.75e-09

Domain of unknown function (DUF4864); This family consists of uncharacterized proteins around 120 residues in length and is mainly found in various Anabaena and Nostoc species. Distant homology analysis suggests this family is related to NTF2-like proteins and specifically to proteins that bind small molecules. HMM partly overlaps with Tol_Tol_Ttg2 (PF05494) involved in Toluene tolerance and lumazine binding family (PF12870) and these families should form a clan.


Pssm-ID: 435176  Cd Length: 101  Bit Score: 52.33  E-value: 2.75e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490728483   91 VVHIQVLALQNNDPATNeginttWQFASPSNRDLTGPYSNFVRTIQSGFEPLLNATGVRYGPLDRDGDTASQPVTVVNEN 170
Cdd:pfam16156   4 VIGSQLAAFRQDDAATA------FEFASPGIQRLFGTPERFLQMVRQGYPPVYRPRSVAFGKRRDIGGGIVQRVRVVDSD 77

                          90       100
                  ....*....|....*....|....*..
gi 490728483  171 GTttsyRWTVEKQTEGRYEGCWMTAGV 197
Cdd:pfam16156  78 GK----AWTAEYQMIRQPDGSWRINGV 100
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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