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Conserved domains on  [gi|490291218|ref|WP_004186823|]
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MULTISPECIES: anthranilate phosphoribosyltransferase [Burkholderia]

Protein Classification

anthranilate phosphoribosyltransferase( domain architecture ID 11478311)

anthranilate phosphoribosyltransferase catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)

Gene Ontology:  GO:0004048|GO:0000162|GO:0046872
PubMed:  36633281|28844746
SCOP:  4003843|4000984

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
trpD PRK00188
anthranilate phosphoribosyltransferase; Provisional
 3-342 0e+00

anthranilate phosphoribosyltransferase; Provisional


:

Pssm-ID: 234682 [Multi-domain]  Cd Length: 339  Bit Score: 513.47  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218   3 ITPQEALQRTIEHREIFHDEMLHLMRLIMRGDMSPVMAAAIITGLRVKKETIGEIAAAATVMREFARRVEveDNANFVDI 82
Cdd:PRK00188   1 MTMKELLEKLVEGEDLSEEEAEELMDAIMSGEATPAQIAAFLTALRVKGETVDEIAGAARAMREHAVPVP--DPDDAVDI 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218  83 VGTGGDGSHTFNISTATMFVAAAAGAKVAKHGNRGVSSKSGSADVLEALGVNIDLQPEQVAASIAETGMGFMFAPNHHPA 162
Cdd:PRK00188  79 VGTGGDGANTFNISTAAAFVAAAAGVKVAKHGNRSVSSKSGSADVLEALGVNLDLSPEQVARCLEEVGIGFLFAPLYHPA 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218 163 MRNIAPVRRELGVRTIFNILGPLTNPADAPNQLMGVFHPDLVGIQVRVMQRLGAQHVLVVYGKDGMDEVSLGAATLVGEL 242
Cdd:PRK00188 159 MKHVAPVRKELGIRTIFNLLGPLTNPARPKRQLIGVYSPDLLEPMAEVLKRLGSKRALVVHGSDGLDEISLTGPTTVAEL 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218 243 RDGEVREYEIHPEDFGMQMVSNRTLKVESADESRVMLLEAL-GNKPGVAREIVTLNAGTALYSADVAGSIADGIQLARDA 321
Cdd:PRK00188 239 KDGEIREYTLTPEDFGLPRAPLEDLRGGDPEENAAILRAVLqGKGPGAARDAVLLNAAAALYVAGKADDLKEGVELAREA 318

                        330       340
                 ....*....|....*....|.
gi 490291218 322 IASGRAREKVDELVRFTQQFK 342
Cdd:PRK00188 319 IDSGAALAKLEELVAFSQELK 339
 
Name Accession Description Interval E-value
trpD PRK00188
anthranilate phosphoribosyltransferase; Provisional
 3-342 0e+00

anthranilate phosphoribosyltransferase; Provisional


Pssm-ID: 234682 [Multi-domain]  Cd Length: 339  Bit Score: 513.47  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218   3 ITPQEALQRTIEHREIFHDEMLHLMRLIMRGDMSPVMAAAIITGLRVKKETIGEIAAAATVMREFARRVEveDNANFVDI 82
Cdd:PRK00188   1 MTMKELLEKLVEGEDLSEEEAEELMDAIMSGEATPAQIAAFLTALRVKGETVDEIAGAARAMREHAVPVP--DPDDAVDI 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218  83 VGTGGDGSHTFNISTATMFVAAAAGAKVAKHGNRGVSSKSGSADVLEALGVNIDLQPEQVAASIAETGMGFMFAPNHHPA 162
Cdd:PRK00188  79 VGTGGDGANTFNISTAAAFVAAAAGVKVAKHGNRSVSSKSGSADVLEALGVNLDLSPEQVARCLEEVGIGFLFAPLYHPA 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218 163 MRNIAPVRRELGVRTIFNILGPLTNPADAPNQLMGVFHPDLVGIQVRVMQRLGAQHVLVVYGKDGMDEVSLGAATLVGEL 242
Cdd:PRK00188 159 MKHVAPVRKELGIRTIFNLLGPLTNPARPKRQLIGVYSPDLLEPMAEVLKRLGSKRALVVHGSDGLDEISLTGPTTVAEL 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218 243 RDGEVREYEIHPEDFGMQMVSNRTLKVESADESRVMLLEAL-GNKPGVAREIVTLNAGTALYSADVAGSIADGIQLARDA 321
Cdd:PRK00188 239 KDGEIREYTLTPEDFGLPRAPLEDLRGGDPEENAAILRAVLqGKGPGAARDAVLLNAAAALYVAGKADDLKEGVELAREA 318

                        330       340
                 ....*....|....*....|.
gi 490291218 322 IASGRAREKVDELVRFTQQFK 342
Cdd:PRK00188 319 IDSGAALAKLEELVAFSQELK 339
TrpD COG0547
Anthranilate phosphoribosyltransferase, glycosyltransferase domain [Amino acid transport and ...
 4-331 2.46e-165

Anthranilate phosphoribosyltransferase, glycosyltransferase domain [Amino acid transport and metabolism]; Anthranilate phosphoribosyltransferase, glycosyltransferase domain is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis


Pssm-ID: 440313 [Multi-domain]  Cd Length: 327  Bit Score: 463.78  E-value: 2.46e-165
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218   4 TPQEALQRTIEHREIFHDEMLHLMRLIMRGDMSPVMAAAIITGLRVKKETIGEIAAAATVMREFARRVEVEDnANFVDIV 83
Cdd:COG0547    1 MMKELLKKLAEGKDLTREEAREAMRQIMSGEATPAQIGAFLTALRMKGETVEEIAGFADAMRELAVPVPLPD-GDVVDIV 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218  84 GTGGDGSHTFNISTATMFVAAAAGAKVAKHGNRGVSSKSGSADVLEALGVNIDLQPEQVAASIAETGMGFMFAPNHHPAM 163
Cdd:COG0547   80 GTGGDGANTFNISTAAAFVAAAAGVPVAKHGNRSVSSKSGSADVLEALGVNLDLSPEQVARCLEEAGIGFLFAPLFHPAM 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218 164 RNIAPVRRELGVRTIFNILGPLTNPADAPNQLMGVFHPDLVGIQVRVMQRLGAQHVLVVYGKDGMDEVSLGAATLVGELR 243
Cdd:COG0547  160 KHVAPVRKELGVRTIFNLLGPLTNPAGPKRQLLGVYHPELVEPLAEVLQLLGVKRALVVHGLDGLDEISLTGPTKVAELR 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218 244 DGEVREYEIHPEDFGMQMVSNRTLKVESADESRVMLLEALGNKPGVAREIVTLNAGTALYSADVAGSIADGIQLARDAIA 323
Cdd:COG0547  240 DGEIEEYTLDPEDFGLPRAPLEDLRGGDAEENAEILRAVLAGEGGPARDAVLLNAAAALYVAGKADSLAEGVELAREAID 319


                 ....*...
gi 490291218 324 SGRAREKV 331
Cdd:COG0547  320 SGAALAKL 327
trpD TIGR01245
anthranilate phosphoribosyltransferase; In many widely different species, including E. coli, ...
 9-337 8.90e-143

anthranilate phosphoribosyltransferase; In many widely different species, including E. coli, Thermotoga maritima, and Archaeoglobus fulgidus, this enzymatic domain (anthranilate phosphoribosyltransferase) is found C-terminal to glutamine amidotransferase; the fusion protein is designated anthranilate synthase component II (EC 4.1.3.27) [Amino acid biosynthesis, Aromatic amino acid family]


Pssm-ID: 273522 [Multi-domain]  Cd Length: 330  Bit Score: 407.04  E-value: 8.90e-143
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218    9 LQRTIEHREIFHDEMLHLMRLIMRGDMSPVMAAAIITGLRVKKETIGEIAAAATVMREFARRVEVEDNANFVDIVGTGGD 88
Cdd:TIGR01245   1 LEKLIDGKDLSRDEAEQLMKEIMSGEASPAQIAAILTALRIKGETPEEITGFAKAMREHAVKVPGRPPEDLVDIVGTGGD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218   89 GSHTFNISTATMFVAAAAGAKVAKHGNRGVSSKSGSADVLEALGVNIDLQPEQVAASIAETGMGFMFAPNHHPAMRNIAP 168
Cdd:TIGR01245  81 GANTINISTASAFVAAAAGVKVAKHGNRSVSSKSGSADVLEALGVNLDLGPEKVARSLEETGIGFLFAPLYHPAMKHVAP 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218  169 VRRELGVRTIFNILGPLTNPADAPNQLMGVFHPDLVGIQVRVMQRLGAQHVLVVYGKDGMDEVSLGAATLVGELRDGEVR 248
Cdd:TIGR01245 161 VRRELGVRTVFNLLGPLTNPARPKYQVIGVYDPDLVEVMAEALKNLGVKRALVVHGDDGLDEISLTGPTTVAELKDGEIR 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218  249 EYEIHPEDFGMQMVSNRTLKVESADESRVMLLEALGNK-PGVAREIVTLNAGTALYSADVAGSIADGIQLARDAIASGRA 327
Cdd:TIGR01245 241 EYTLDPEDFGLPRAPLEELAGGSPEENAEILRDILRGKgSGAKRDIVALNAAAALYVAGRASDLKEGVELALEAIDSGAA 320

                         330
                  ....*....|
gi 490291218  328 REKVDELVRF 337
Cdd:TIGR01245 321 AEKLEELVAF 330
Glycos_transf_3 pfam00591
Glycosyl transferase family, a/b domain; This family includes anthranilate ...
 76-328 2.16e-98

Glycosyl transferase family, a/b domain; This family includes anthranilate phosphoribosyltransferase (TrpD), thymidine phosphorylase. All these proteins can transfer a phosphorylated ribose substrate.


Pssm-ID: 459860 [Multi-domain]  Cd Length: 253  Bit Score: 291.11  E-value: 2.16e-98
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218   76 NANFVDIVGTGGDGSHTFNISTATMFVAAAAGAKVAKHGNRGVSSKSGSADVLEALGVNIDLQPEQVAASIAETGMGFMF 155
Cdd:pfam00591   1 LGDLVDIVGTGGDGDNTFNISTAAAIVAAACGVKVAKHGNRSVSSKSGSADVLEALGINLDLTPEQVRKLLDEVGVGFLF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218  156 APNHHPAMRNIAPVRRELGVRTIFNILGPLTNPADAPNQLMGVFHPDLVGIQVRVMQRLGAQHVLVVYGkDGMDEVSLGA 235
Cdd:pfam00591  81 APNYHPAMKHVAPVRRELGIRTVFNLLGPLINPARVKRQVLGVYSKELAEGLAEVLKDLGRERAAVVHG-DGLDEASLLG 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218  236 ATLVGELRDGEVREYEIHPEDFGMQMVSNRTLKVESADESRVMLLEALGNKPG-VAREIVTLNAGTALYSADVAGSIADG 314
Cdd:pfam00591 160 KTTVAELKDGEITEYTLTPEDFGLGRATLEALEGGSPKENADILKGVLGGKGSaAHRDLVALNAGAALYLAGKADSLKEG 239

                         250
                  ....*....|....
gi 490291218  315 IQLARDAIASGRAR 328
Cdd:pfam00591 240 VAKALEVIDSGKAL 253
 
Name Accession Description Interval E-value
trpD PRK00188
anthranilate phosphoribosyltransferase; Provisional
 3-342 0e+00

anthranilate phosphoribosyltransferase; Provisional


Pssm-ID: 234682 [Multi-domain]  Cd Length: 339  Bit Score: 513.47  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218   3 ITPQEALQRTIEHREIFHDEMLHLMRLIMRGDMSPVMAAAIITGLRVKKETIGEIAAAATVMREFARRVEveDNANFVDI 82
Cdd:PRK00188   1 MTMKELLEKLVEGEDLSEEEAEELMDAIMSGEATPAQIAAFLTALRVKGETVDEIAGAARAMREHAVPVP--DPDDAVDI 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218  83 VGTGGDGSHTFNISTATMFVAAAAGAKVAKHGNRGVSSKSGSADVLEALGVNIDLQPEQVAASIAETGMGFMFAPNHHPA 162
Cdd:PRK00188  79 VGTGGDGANTFNISTAAAFVAAAAGVKVAKHGNRSVSSKSGSADVLEALGVNLDLSPEQVARCLEEVGIGFLFAPLYHPA 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218 163 MRNIAPVRRELGVRTIFNILGPLTNPADAPNQLMGVFHPDLVGIQVRVMQRLGAQHVLVVYGKDGMDEVSLGAATLVGEL 242
Cdd:PRK00188 159 MKHVAPVRKELGIRTIFNLLGPLTNPARPKRQLIGVYSPDLLEPMAEVLKRLGSKRALVVHGSDGLDEISLTGPTTVAEL 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218 243 RDGEVREYEIHPEDFGMQMVSNRTLKVESADESRVMLLEAL-GNKPGVAREIVTLNAGTALYSADVAGSIADGIQLARDA 321
Cdd:PRK00188 239 KDGEIREYTLTPEDFGLPRAPLEDLRGGDPEENAAILRAVLqGKGPGAARDAVLLNAAAALYVAGKADDLKEGVELAREA 318

                        330       340
                 ....*....|....*....|.
gi 490291218 322 IASGRAREKVDELVRFTQQFK 342
Cdd:PRK00188 319 IDSGAALAKLEELVAFSQELK 339
TrpD COG0547
Anthranilate phosphoribosyltransferase, glycosyltransferase domain [Amino acid transport and ...
 4-331 2.46e-165

Anthranilate phosphoribosyltransferase, glycosyltransferase domain [Amino acid transport and metabolism]; Anthranilate phosphoribosyltransferase, glycosyltransferase domain is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis


Pssm-ID: 440313 [Multi-domain]  Cd Length: 327  Bit Score: 463.78  E-value: 2.46e-165
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218   4 TPQEALQRTIEHREIFHDEMLHLMRLIMRGDMSPVMAAAIITGLRVKKETIGEIAAAATVMREFARRVEVEDnANFVDIV 83
Cdd:COG0547    1 MMKELLKKLAEGKDLTREEAREAMRQIMSGEATPAQIGAFLTALRMKGETVEEIAGFADAMRELAVPVPLPD-GDVVDIV 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218  84 GTGGDGSHTFNISTATMFVAAAAGAKVAKHGNRGVSSKSGSADVLEALGVNIDLQPEQVAASIAETGMGFMFAPNHHPAM 163
Cdd:COG0547   80 GTGGDGANTFNISTAAAFVAAAAGVPVAKHGNRSVSSKSGSADVLEALGVNLDLSPEQVARCLEEAGIGFLFAPLFHPAM 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218 164 RNIAPVRRELGVRTIFNILGPLTNPADAPNQLMGVFHPDLVGIQVRVMQRLGAQHVLVVYGKDGMDEVSLGAATLVGELR 243
Cdd:COG0547  160 KHVAPVRKELGVRTIFNLLGPLTNPAGPKRQLLGVYHPELVEPLAEVLQLLGVKRALVVHGLDGLDEISLTGPTKVAELR 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218 244 DGEVREYEIHPEDFGMQMVSNRTLKVESADESRVMLLEALGNKPGVAREIVTLNAGTALYSADVAGSIADGIQLARDAIA 323
Cdd:COG0547  240 DGEIEEYTLDPEDFGLPRAPLEDLRGGDAEENAEILRAVLAGEGGPARDAVLLNAAAALYVAGKADSLAEGVELAREAID 319


                 ....*...
gi 490291218 324 SGRAREKV 331
Cdd:COG0547  320 SGAALAKL 327
trpD TIGR01245
anthranilate phosphoribosyltransferase; In many widely different species, including E. coli, ...
 9-337 8.90e-143

anthranilate phosphoribosyltransferase; In many widely different species, including E. coli, Thermotoga maritima, and Archaeoglobus fulgidus, this enzymatic domain (anthranilate phosphoribosyltransferase) is found C-terminal to glutamine amidotransferase; the fusion protein is designated anthranilate synthase component II (EC 4.1.3.27) [Amino acid biosynthesis, Aromatic amino acid family]


Pssm-ID: 273522 [Multi-domain]  Cd Length: 330  Bit Score: 407.04  E-value: 8.90e-143
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218    9 LQRTIEHREIFHDEMLHLMRLIMRGDMSPVMAAAIITGLRVKKETIGEIAAAATVMREFARRVEVEDNANFVDIVGTGGD 88
Cdd:TIGR01245   1 LEKLIDGKDLSRDEAEQLMKEIMSGEASPAQIAAILTALRIKGETPEEITGFAKAMREHAVKVPGRPPEDLVDIVGTGGD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218   89 GSHTFNISTATMFVAAAAGAKVAKHGNRGVSSKSGSADVLEALGVNIDLQPEQVAASIAETGMGFMFAPNHHPAMRNIAP 168
Cdd:TIGR01245  81 GANTINISTASAFVAAAAGVKVAKHGNRSVSSKSGSADVLEALGVNLDLGPEKVARSLEETGIGFLFAPLYHPAMKHVAP 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218  169 VRRELGVRTIFNILGPLTNPADAPNQLMGVFHPDLVGIQVRVMQRLGAQHVLVVYGKDGMDEVSLGAATLVGELRDGEVR 248
Cdd:TIGR01245 161 VRRELGVRTVFNLLGPLTNPARPKYQVIGVYDPDLVEVMAEALKNLGVKRALVVHGDDGLDEISLTGPTTVAELKDGEIR 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218  249 EYEIHPEDFGMQMVSNRTLKVESADESRVMLLEALGNK-PGVAREIVTLNAGTALYSADVAGSIADGIQLARDAIASGRA 327
Cdd:TIGR01245 241 EYTLDPEDFGLPRAPLEELAGGSPEENAEILRDILRGKgSGAKRDIVALNAAAALYVAGRASDLKEGVELALEAIDSGAA 320

                         330
                  ....*....|
gi 490291218  328 REKVDELVRF 337
Cdd:TIGR01245 321 AEKLEELVAF 330
PRK14607 PRK14607
bifunctional anthranilate synthase component II/anthranilate phosphoribosyltransferase;
3-340 8.51e-111

bifunctional anthranilate synthase component II/anthranilate phosphoribosyltransferase;


Pssm-ID: 237764 [Multi-domain]  Cd Length: 534  Bit Score: 332.84  E-value: 8.51e-111
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218   3 ITPQEALQRTIEHREIFHDEMLHLMRLIMRGDMSPVMAAAIITGLRVKKETIGEIAAAATVMREFARRVEVEDNaNFVDI 82
Cdd:PRK14607 193 IDIKSYLKKLVEGEDLSFEEAEDVMEDITDGNATDAQIAGFLTALRMKGETADELAGFASVMREKSRHIPAPSP-RTVDT 271

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218  83 VGTGGDGSHTFNISTATMFVAAAAGAKVAKHGNRGVSSKSGSADVLEALGVNIDLQPEQVAASIAETGMGFMFAPNHHPA 162
Cdd:PRK14607 272 CGTGGDGFGTFNISTTSAFVVAAAGVPVAKHGNRAVSSKSGSADVLEALGVKLEMTPEEAASVLRETGFSFLFAPLFHPA 351

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218 163 MRNIAPVRRELGVRTIFNILGPLTNPADAPNQLMGVFHPDLVGIQVRVMQRLGAQHVLVVYGKDGMDEVSLGAATLVGEL 242
Cdd:PRK14607 352 MKHAAPARRELGIRTAFNLLGPLTNPARVKYQIVGVFDPSYAEPLAQALQRLGTERAMVVSGIDGYDEISTCGPTQILEL 431

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218 243 RDGEVREYEIHPEDFGMQMVSNRTLKVESADESRVMLLEALGNKP-GVAREIVTLNAGTALYSADVAGSIADGIQLARDA 321
Cdd:PRK14607 432 EDGEIVTYTFDPEELGLKRVDPEELKGGDPQENYRLAEDVLKGEPrRPQRDAVALNAGAALYLVGEADSIKEGVGKALDL 511

                        330
                 ....*....|....*....
gi 490291218 322 IASGRAREKVDELVRFTQQ 340
Cdd:PRK14607 512 IDDGRAYKKLEEVMDLSKT 530
Glycos_transf_3 pfam00591
Glycosyl transferase family, a/b domain; This family includes anthranilate ...
 76-328 2.16e-98

Glycosyl transferase family, a/b domain; This family includes anthranilate phosphoribosyltransferase (TrpD), thymidine phosphorylase. All these proteins can transfer a phosphorylated ribose substrate.


Pssm-ID: 459860 [Multi-domain]  Cd Length: 253  Bit Score: 291.11  E-value: 2.16e-98
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218   76 NANFVDIVGTGGDGSHTFNISTATMFVAAAAGAKVAKHGNRGVSSKSGSADVLEALGVNIDLQPEQVAASIAETGMGFMF 155
Cdd:pfam00591   1 LGDLVDIVGTGGDGDNTFNISTAAAIVAAACGVKVAKHGNRSVSSKSGSADVLEALGINLDLTPEQVRKLLDEVGVGFLF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218  156 APNHHPAMRNIAPVRRELGVRTIFNILGPLTNPADAPNQLMGVFHPDLVGIQVRVMQRLGAQHVLVVYGkDGMDEVSLGA 235
Cdd:pfam00591  81 APNYHPAMKHVAPVRRELGIRTVFNLLGPLINPARVKRQVLGVYSKELAEGLAEVLKDLGRERAAVVHG-DGLDEASLLG 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218  236 ATLVGELRDGEVREYEIHPEDFGMQMVSNRTLKVESADESRVMLLEALGNKPG-VAREIVTLNAGTALYSADVAGSIADG 314
Cdd:pfam00591 160 KTTVAELKDGEITEYTLTPEDFGLGRATLEALEGGSPKENADILKGVLGGKGSaAHRDLVALNAGAALYLAGKADSLKEG 239

                         250
                  ....*....|....
gi 490291218  315 IQLARDAIASGRAR 328
Cdd:pfam00591 240 VAKALEVIDSGKAL 253
PLN02641 PLN02641
anthranilate phosphoribosyltransferase
 34-342 8.20e-93

anthranilate phosphoribosyltransferase


Pssm-ID: 215345 [Multi-domain]  Cd Length: 343  Bit Score: 280.47  E-value: 8.20e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218  34 DMSPVMAAAIITGLRVKKETIGEIAAAATVMREFARRVEVEDNAnfVDIVGTGGDGSHTFNISTATMFVAAAAGAKVAKH 113
Cdd:PLN02641  32 DADEAQISAFLVLLRAKGETFEEIAGLARAMIKRARKVDGLVDA--VDIVGTGGDGANTVNISTGSSILAAACGAKVAKQ 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218 114 GNRGVSSKSGSADVLEALGVNIDLQPEQVAASIAETGMGFMFAPNHHPAMRNIAPVRRELGVRTIFNILGPLTNPADAPN 193
Cdd:PLN02641 110 GNRSSSSACGSADVLEALGVAIDLGPEGVKRCVEEVGIGFMMAPKYHPAMKIVAPVRKKLKVKTVFNILGPMLNPARVPH 189

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218 194 QLMGVFHPDLVGIQVRVMQRLGAQHVLVVYGKdGMDEVS-LGAATLVgELRDGEVREYEIHPEDFGMQMVSNRTLKVESA 272
Cdd:PLN02641 190 AVVGVYHESLVEKMAKALQRFGMKRALVVHSE-GLDEMSpLGPGDVL-EVTPEKIEEFSFDPLDFGIPRCTLEDLRGGDP 267

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218 273 DESRVMLLEALGNKPGVAREIVTLNAGTALYSADVAGSIADGIQLARDAIASGRAREKVDELVRFTQQFK 342
Cdd:PLN02641 268 DYNAKVLRDVLSGEKGAIADALILNAAAALLVSGLAKTLAEGVALARETQESGKAIKTLDSWIKISQELK 337
PRK09522 PRK09522
bifunctional anthranilate synthase glutamate amidotransferase component TrpG/anthranilate ...
 4-334 5.38e-72

bifunctional anthranilate synthase glutamate amidotransferase component TrpG/anthranilate phosphoribosyltransferase TrpD;


Pssm-ID: 181927 [Multi-domain]  Cd Length: 531  Bit Score: 232.61  E-value: 5.38e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218   4 TPQEALQRTIEHREIFHDEMLHLMRLIMRGDMSPVMAAAIITGLRVKKETIGEIAAAATVMREFARRVEVEDNAnFVDIV 83
Cdd:PRK09522 199 TLQPILEKLYQAQTLSQQESHQLFSAVVRGELKPEQLAAALVSMKIRGEHPNEIAGAATALLENAAPFPRPDYL-FADIV 277

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218  84 GTGGDGSHTFNISTATMFVAAAAGAKVAKHGNRGVSSKSGSADVLEALGVNIDLQPEQVAASIAETGMGFMFAPNHHPAM 163
Cdd:PRK09522 278 GTGGDGSNSINISTASAFVAAACGLKVAKHGNRSVSSKSGSSDLLAAFGINLDMNADKSRQALDELGVCFLFAPKYHTGF 357

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218 164 RNIAPVRRELGVRTIFNILGPLTNPADAPNQLMGVFHPDLVGIQVRVMQRLGAQHVLVVYGkDGMDEVSLGAATLVGELR 243
Cdd:PRK09522 358 RHAMPVRQQLKTRTLFNVLGPLINPAHPPLALIGVYSPELVLPIAETLRVLGYQRAAVVHS-GGMDEVSLHAPTIVAELH 436

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218 244 DGEVREYEIHPEDFGMQMVSNRTLKVESADESRVMLLEALGNKPGVAREIVTLNAGTALYSADVAGSIADGIQLARDAIA 323
Cdd:PRK09522 437 DGEIKSYQLTAEDFGLTPYHQEQLAGGTPEENRDILTRLLQGKGDAAHEAAVAANVAMLMRLHGHEDLQANAQTVLEVLR 516

                        330
                 ....*....|.
gi 490291218 324 SGRAREKVDEL 334
Cdd:PRK09522 517 SGSAYDRVTAL 527
PRK07394 PRK07394
hypothetical protein; Provisional
 27-334 2.81e-24

hypothetical protein; Provisional


Pssm-ID: 168934 [Multi-domain]  Cd Length: 342  Bit Score: 101.14  E-value: 2.81e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218  27 MRLIMRGDMSPVMAAAIITGLRVKKETIGEIAAAATVMREFARRVEVEDNANFVDIVGTGGDG-SHTFNISTATMFVAAA 105
Cdd:PRK07394  31 LKLMLLGEATPAQIGAFLIAHRIKRPTPEELAGMLDTYDELGPKLQSPSNQRPPIVFGMPYDGrSRTAPIYPLTALILAA 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218 106 AGAKVAKHGNRGVSSKSG--SADVLEALGVNID-LQPEQVAASIAETGMGFMFAPNHHPAMRNIAPVRRELGVRTIFNIL 182
Cdd:PRK07394 111 AGQPVVLHGGDRMPTKYGvpLVELWQGLGVDLTgLSLEQVQEGFEQTGLAFIYQPDHFPLAESLIPYRDEIGKRPPLATL 190

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218 183 GPLTNPADAPNQLM-GVFHPDLVGIQVRVMQRLGAQHVLVVYGKDGMDEVSLGAATLVGELRDGEVREYEIHPEDFGMqm 261
Cdd:PRK07394 191 ELIWTPHQGDHHLVsGFVHPPTEARAWEALELRGETNFTTVKGLEGSCDLPISRTAIIGRVQNGHFERLILHPRDYGC-- 268

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 490291218 262 vSNRTLKVESADESRVMLLEALGNKPGVAREIVTLNAGTALYSADVAGSIADGIQLARDAIASGRAREKVDEL 334
Cdd:PRK07394 269 -GGKDVPWESTEEWLEQAQAALNGEPGPLTQALIWNGGFYLWRAGISSSLEEGIEKAEELLNSGKALQKLQQL 340
Glycos_trans_3N pfam02885
Glycosyl transferase family, helical bundle domain; This family includes anthranilate ...
 6-68 4.37e-14

Glycosyl transferase family, helical bundle domain; This family includes anthranilate phosphoribosyltransferase (TrpD), thymidine phosphorylase. All these proteins can transfer a phosphorylated ribose substrate.


Pssm-ID: 460737 [Multi-domain]  Cd Length: 63  Bit Score: 66.25  E-value: 4.37e-14
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 490291218    6 QEALQRTIEHREIFHDEMLHLMRLIMRGDMSPVMAAAIITGLRVKKETIGEIAAAATVMREFA 68
Cdd:pfam02885   1 KELIKKLRDGEDLTREEARAAMDGIMSGEATDAQIAAFLMALRMKGETAEEIAGLARAMRESG 63
PRK09071 PRK09071
glycosyl transferase family protein;
21-251 2.27e-12

glycosyl transferase family protein;


Pssm-ID: 181637 [Multi-domain]  Cd Length: 323  Bit Score: 66.86  E-value: 2.27e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218  21 DEMLHLMRLIMRGDMSPVMAAAIITGLRVKKETIGEIAAAATVMREfarRVEVEDNANFVDIVGTGGDGSHT--FNISTA 98
Cdd:PRK09071  24 EEARQAMGMILDGEVEDDQLGAFLMLLRVKEETAEELAGFVEAIRE---RLQAPPLAVDLDWPSYAGKRRHLpwYLLAAK 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218  99 TMfvaAAAGAKVAKHGNRGVSSKSGSA-DVLEALGVNIDLQPEQVAASIAETGMGFMFAPNHHPAMRNIAPVRRELGVRT 177
Cdd:PRK09071 101 LL---AQNGYRVLLHGGGGHTAGRLYTeQLLEALGIPIARSWQEAEQALEEHNIAYLPLEDFAPQLQRMIDLRNTLGLRS 177

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 490291218 178 IFNILGPLTNPADAPNQLMGVFHPDLVGIQVRVMQRLGAQHVLVVYGKDGMDEVSLGAATLVGELRDGEVREYE 251
Cdd:PRK09071 178 PINTLARLLNPLNAKASLQGIFHPGYQQLHREAARLLGDQNALVFKGEGGESERNPDVSTTLYGSRNGEAWDEE 251
PRK08136 PRK08136
glycosyl transferase family protein; Provisional
 113-227 7.61e-03

glycosyl transferase family protein; Provisional


Pssm-ID: 236160 [Multi-domain]  Cd Length: 317  Bit Score: 37.54  E-value: 7.61e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490291218 113 HGNRGVSSKSGSADVLEALGVNIDLQPEQVAASIAETGMGFMFAPNHHPAMRNIAPVRRELGVRTIFNILGPLTNP--AD 190
Cdd:PRK08136 115 HGVSEDPTRVTSAEIFEALGIPPTLHADQAQAKLAEGQPAFIPVGVLCPPLARLLALRWRMGVRNSAHTLAKLATPfaEG 194

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 490291218 191 APNQLMGVFHPDLVGIQVRVMQRLGAqHVLVVYGKDG 227
Cdd:PRK08136 195 AALRLSSYTHPEYRDRLAEFFSDIGA-RALLMRGTEG 230
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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