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Conserved domains on  [gi|490176572|ref|WP_004075202|]
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glycosyltransferase [Desulfobacter postgatei]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
WcaA COG0463
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ...
 519-710 4.33e-40

Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 440231 [Multi-domain]  Cd Length: 208  Bit Score: 147.16  E-value: 4.33e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  519 KPLISVIMPVYNRVAIVGEAIASVLAQSYHYFELIVVDDCSTDATESAVQAF--HDDRIRLITLPENKGPSAARNAGLQV 596
Cdd:COG0463     1 MPLVSVVIPTYNEEEYLEEALESLLAQTYPDFEIIVVDDGSTDGTAEILRELaaKDPRIRVIRLERNRGKGAARNAGLAA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  597 AQGEILAYLDSDNTWDDRYLAAIAGAFETLPdADAVYSGILLYRNRDSSPFAVRYGHYHRALLENRNYIDMNIFSHRRGL 676
Cdd:COG0463    81 ARGDYIAFLDADDQLDPEKLEELVAALEEGP-ADLVYGSRLIREGESDLRRLGSRLFNLVRLLTNLPDSTSGFRLFRREV 159

                         170       180       190
                  ....*....|....*....|....*....|....
gi 490176572  677 MDRMsGFDQNMkrYVDYDFILRASESGTVYSVPI 710
Cdd:COG0463   160 LEEL-GFDEGF--LEDTELLRALRHGFRIAEVPV 190
WcaE COG1216
Glycosyltransferase, GT2 family [Carbohydrate transport and metabolism];
761-992 2.21e-23

Glycosyltransferase, GT2 family [Carbohydrate transport and metabolism];


:

Pssm-ID: 440829 [Multi-domain]  Cd Length: 202  Bit Score: 98.91  E-value: 2.21e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  761 VAVIIPNWQSLDEINECLDALTAKDWkGQLKIIVIDNASDRDVVNYLvDREAAGDIDLIQNKRNYGFTYAVNQGIRraHA 840
Cdd:COG1216     5 VSVVIPTYNRPELLRRCLESLLAQTY-PPFEVIVVDNGSTDGTAELL-AALAFPRVRVIRNPENLGFAAARNLGLR--AA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  841 GAD-ILVLNNDAVVRKGAIQALQKACyslphagmtvprqilpagtktfqthvpfasedydcdvnisahhrniarvpvfhn 919
Cdd:COG1216    81 GGDyLLFLDDDTVVEPDWLERLLAAA------------------------------------------------------ 106

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 490176572  920 gknlelsfapffAVYIQRDLIARIGVLDAEYGrHYRSDRVYCDMARNVGGkKIYYVPDAFVIHKLQKATDSLR 992
Cdd:COG1216   107 ------------CLLIRREVFEEVGGFDERFF-LYGEDVDLCLRLRKAGY-RIVYVPDAVVYHLGGASSGPLL 165
RgpF super family cl18453
Rhamnan synthesis protein F; This family consists of a group of proteins which are related to ...
 101-318 1.17e-17

Rhamnan synthesis protein F; This family consists of a group of proteins which are related to the Streptococcus rhamnose-glucose polysaccharide assembly protein (RgpF). Rhamnan backbones are found in several O polysaccharides of phytopathogenic bacteria and are regarded as pathogenic factors.


The actual alignment was detected with superfamily member pfam05045:

Pssm-ID: 428278  Cd Length: 500  Bit Score: 87.39  E-value: 1.17e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572   101 RYALVIHVFYLDILGDLKASAAHFPESGDIFVTCPDSFSRIECDDIRSFFPR-AEIIQVPNVNQDVGALmgLMAQVDF-R 178
Cdd:pfam05045  270 RIAVHLHVYYEDLLEEFLHYFKSFPFEYDLYITTDSEEKKKLIKEILKELSYkAKVRLVGNRGRDVSPF--LVGLKDElM 347

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572   179 DYGFICKIHSKKGNKCP-----EKWRRALLDGVLGSKAQVERTIRLFQSDDELMIggakqLFLHGPS--------NLWKN 245
Cdd:pfam05045  348 KYDYICHFHDKKSTQASpysvgDSFRYECFDNLLKSKGYVDNIIATFEQNPRLGI-----LIPPPPNhgryntivDEWNE 422

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 490176572   246 KALISNVFGPFLG-DFDFERADwGFFA--GTCFWIRTSILCKIKEHMDGLENRPGAYVDG-GTAAHAAERMFGLLVA 318
Cdd:pfam05045  423 NAEVMKDLAERLGiKVPFDDFK-EPVAplGTMFWFRPKALKPLFDLDWKYEDFPAEPLKPdGTILHAIERLYGYAAQ 498
 
Name Accession Description Interval E-value
WcaA COG0463
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ...
 519-710 4.33e-40

Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440231 [Multi-domain]  Cd Length: 208  Bit Score: 147.16  E-value: 4.33e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  519 KPLISVIMPVYNRVAIVGEAIASVLAQSYHYFELIVVDDCSTDATESAVQAF--HDDRIRLITLPENKGPSAARNAGLQV 596
Cdd:COG0463     1 MPLVSVVIPTYNEEEYLEEALESLLAQTYPDFEIIVVDDGSTDGTAEILRELaaKDPRIRVIRLERNRGKGAARNAGLAA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  597 AQGEILAYLDSDNTWDDRYLAAIAGAFETLPdADAVYSGILLYRNRDSSPFAVRYGHYHRALLENRNYIDMNIFSHRRGL 676
Cdd:COG0463    81 ARGDYIAFLDADDQLDPEKLEELVAALEEGP-ADLVYGSRLIREGESDLRRLGSRLFNLVRLLTNLPDSTSGFRLFRREV 159

                         170       180       190
                  ....*....|....*....|....*....|....
gi 490176572  677 MDRMsGFDQNMkrYVDYDFILRASESGTVYSVPI 710
Cdd:COG0463   160 LEEL-GFDEGF--LEDTELLRALRHGFRIAEVPV 190
GT2_RfbC_Mx_like cd04184
Myxococcus xanthus RfbC like proteins are required for O-antigen biosynthesis; The rfbC gene ...
 520-714 2.47e-34

Myxococcus xanthus RfbC like proteins are required for O-antigen biosynthesis; The rfbC gene encodes a predicted protein of 1,276 amino acids, which is required for O-antigen biosynthesis in Myxococcus xanthus. It is a subfamily of Glycosyltransferase Family GT2, which includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds.


Pssm-ID: 133027 [Multi-domain]  Cd Length: 202  Bit Score: 130.40  E-value: 2.47e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  520 PLISVIMPVYNR-VAIVGEAIASVLAQSYHYFELIVVDDCSTDA-TESAVQAF--HDDRIRLITLPENKGPSAARNAGLQ 595
Cdd:cd04184     1 PLISIVMPVYNTpEKYLREAIESVRAQTYPNWELCIADDASTDPeVKRVLKKYaaQDPRIKVVFREENGGISAATNSALE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  596 VAQGEILAYLDSDNTWDDRYLAAIAGAFETLPDADAVYSgillyrNRDS-SPFAVRYGHYHR-----ALLENRNYIDmNI 669
Cdd:cd04184    81 LATGEFVALLDHDDELAPHALYEVVKALNEHPDADLIYS------DEDKiDEGGKRSEPFFKpdwspDLLLSQNYIG-HL 153

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 490176572  670 FSHRRGLMDRMSGFDQNMKRYVDYDFILRASESGT-VYSVPILLCR 714
Cdd:cd04184   154 LVYRRSLVRQVGGFREGFEGAQDYDLVLRVSEHTDrIAHIPRVLYH 199
Glycos_transf_2 pfam00535
Glycosyl transferase family 2; Diverse family, transferring sugar from UDP-glucose, ...
 523-670 3.38e-32

Glycosyl transferase family 2; Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.


Pssm-ID: 425738 [Multi-domain]  Cd Length: 166  Bit Score: 123.27  E-value: 3.38e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572   523 SVIMPVYNRVAIVGEAIASVLAQSYHYFELIVVDDCSTDATESAVQAFH--DDRIRLITLPENKGPSAARNAGLQVAQGE 600
Cdd:pfam00535    1 SVIIPTYNEEKYLLETLESLLNQTYPNFEIIVVDDGSTDGTVEIAEEYAkkDPRVRVIRLPENRGKAGARNAGLRAATGD 80

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572   601 ILAYLDSDNTWDDRYLAAIAGAFETLPDADAVYSGILLYRNRDSSPFAVRYGHYHRALLENRNYIDMNIF 670
Cdd:pfam00535   81 YIAFLDADDEVPPDWLEKLVEALEEDGADVVVGSRYVIFGETGEYRRASRITLSRLPFFLGLRLLGLNLP 150
WcaE COG1216
Glycosyltransferase, GT2 family [Carbohydrate transport and metabolism];
761-992 2.21e-23

Glycosyltransferase, GT2 family [Carbohydrate transport and metabolism];


Pssm-ID: 440829 [Multi-domain]  Cd Length: 202  Bit Score: 98.91  E-value: 2.21e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  761 VAVIIPNWQSLDEINECLDALTAKDWkGQLKIIVIDNASDRDVVNYLvDREAAGDIDLIQNKRNYGFTYAVNQGIRraHA 840
Cdd:COG1216     5 VSVVIPTYNRPELLRRCLESLLAQTY-PPFEVIVVDNGSTDGTAELL-AALAFPRVRVIRNPENLGFAAARNLGLR--AA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  841 GAD-ILVLNNDAVVRKGAIQALQKACyslphagmtvprqilpagtktfqthvpfasedydcdvnisahhrniarvpvfhn 919
Cdd:COG1216    81 GGDyLLFLDDDTVVEPDWLERLLAAA------------------------------------------------------ 106

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 490176572  920 gknlelsfapffAVYIQRDLIARIGVLDAEYGrHYRSDRVYCDMARNVGGkKIYYVPDAFVIHKLQKATDSLR 992
Cdd:COG1216   107 ------------CLLIRREVFEEVGGFDERFF-LYGEDVDLCLRLRKAGY-RIVYVPDAVVYHLGGASSGPLL 165
mycofact_glyco TIGR03965
mycofactocin system glycosyltransferase; Members of this protein family are putative ...
 494-703 7.70e-21

mycofactocin system glycosyltransferase; Members of this protein family are putative glycosyltransferases, members of pfam00535 (glycosyl transferase family 2). Members appear mostly in the Actinobacteria, where they appear to be part of a system for converting a precursor peptide (TIGR03969) into a novel redox carrier designated mycofactocin. A radical SAM enzyme, TIGR03962, is a proposed to be a key maturase for mycofactocin.


Pssm-ID: 274884 [Multi-domain]  Cd Length: 466  Bit Score: 97.14  E-value: 7.70e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572   494 ADKRSLAVMEGIANRFCA--IAGKLESKPLISVIMPVYNRVAIVGEAIASVLAQSYH--YFELIVVDDCSTDATESAVQA 569
Cdd:TIGR03965   46 RDETSAALLRRLLDSGVVhpRPALLPSPPSVTVVVPVRNRPAGLARLLAALLALDYPrdRLEVIVVDDGSEDPVPTRAAR 125

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572   570 FHDDRIRLITLPENKGPSAARNAGLQVAQGEILAYLDSDNTWDDRYLAAIAGAFETlPDADAVYSGILLYRNRDsSPFAv 649
Cdd:TIGR03965  126 GARLPVRVIRHPRRQGPAAARNAGARAARTEFVAFTDSDVVPRPGWLRALLAHFDD-PGVALVAPRVVALPAAD-TRLA- 202

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 490176572   650 RYGHYHRALLENRN-----------YIDMNIFSHRRGLMDRMSGFDQNMKRYVDYDFILRASESG 703
Cdd:TIGR03965  203 RYEAVRSSLDLGPEeavvrprgpvsYVPSAALLVRRRALLEVGGFDERLEVGEDVDLCWRLCEAG 267
GT_2_like_c cd04186
Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse ...
 763-983 2.59e-20

Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.


Pssm-ID: 133029 [Multi-domain]  Cd Length: 166  Bit Score: 89.16  E-value: 2.59e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  763 VIIPNWQSLDEINECLDALTAKDwKGQLKIIVIDNASDRDVVNYLvdREAAGDIDLIQNKRNYGFTYAVNQGIRraHAGA 842
Cdd:cd04186     1 IIIVNYNSLEYLKACLDSLLAQT-YPDFEVIVVDNASTDGSVELL--RELFPEVRLIRNGENLGFGAGNNQGIR--EAKG 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  843 D-ILVLNNDAVVRKGAIQALQKACYSLPHAGMTVPRqiLPAGtktfqthvpfasedydcdvnisahhrniarvpvfhngk 921
Cdd:cd04186    76 DyVLLLNPDTVVEPGALLELLDAAEQDPDVGIVGPK--VSGA-------------------------------------- 115

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 490176572  922 nlelsfapffAVYIQRDLIARIGVLDAEYgRHYRSDRVYCDMARNvGGKKIYYVPDAFVIHK 983
Cdd:cd04186   116 ----------FLLVRREVFEEVGGFDEDF-FLYYEDVDLCLRARL-AGYRVLYVPQAVIYHH 165
PRK10018 PRK10018
colanic acid biosynthesis glycosyltransferase WcaA;
519-740 6.88e-20

colanic acid biosynthesis glycosyltransferase WcaA;


Pssm-ID: 182197 [Multi-domain]  Cd Length: 279  Bit Score: 91.21  E-value: 6.88e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  519 KPLISVIMPVYNRVAIVGEAIASVLAQSYHYFELIVVDDCST--DATESAVQAFHDDRIRLITLPENKGPSAARNAGLQV 596
Cdd:PRK10018    4 NPLISIYMPTWNRQQLAIRAIKSVLRQDYSNWEMIIVDDCSTswEQLQQYVTALNDPRITYIHNDINSGACAVRNQAIML 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  597 AQGEILAYLDSDNTWDDRYLAAIAGAFETLPDADAVYSGILL-----YRNRDSSPFAVRyGHYHRALLENRNYIDMNIFS 671
Cdd:PRK10018   84 AQGEYITGIDDDDEWTPNRLSVFLAHKQQLVTHAFLYANDYVcqgevYSQPASLPLYPK-SPYSRRLFYKRNIIGNQVFT 162

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 490176572  672 HRRGLMDRMsgFDQNMKRYVDYDFILR-ASESGTVYSVPILLCRYNYNKADNTVTADP-RYESHLNPIHKH 740
Cdd:PRK10018  163 WAWRFKECL--FDTELKAAQDYDIFLRmVVEYGEPWKVEEATQILHINHGEMQITSSPkKFSGYFHFYRKH 231
RgpF pfam05045
Rhamnan synthesis protein F; This family consists of a group of proteins which are related to ...
 101-318 1.17e-17

Rhamnan synthesis protein F; This family consists of a group of proteins which are related to the Streptococcus rhamnose-glucose polysaccharide assembly protein (RgpF). Rhamnan backbones are found in several O polysaccharides of phytopathogenic bacteria and are regarded as pathogenic factors.


Pssm-ID: 428278  Cd Length: 500  Bit Score: 87.39  E-value: 1.17e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572   101 RYALVIHVFYLDILGDLKASAAHFPESGDIFVTCPDSFSRIECDDIRSFFPR-AEIIQVPNVNQDVGALmgLMAQVDF-R 178
Cdd:pfam05045  270 RIAVHLHVYYEDLLEEFLHYFKSFPFEYDLYITTDSEEKKKLIKEILKELSYkAKVRLVGNRGRDVSPF--LVGLKDElM 347

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572   179 DYGFICKIHSKKGNKCP-----EKWRRALLDGVLGSKAQVERTIRLFQSDDELMIggakqLFLHGPS--------NLWKN 245
Cdd:pfam05045  348 KYDYICHFHDKKSTQASpysvgDSFRYECFDNLLKSKGYVDNIIATFEQNPRLGI-----LIPPPPNhgryntivDEWNE 422

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 490176572   246 KALISNVFGPFLG-DFDFERADwGFFA--GTCFWIRTSILCKIKEHMDGLENRPGAYVDG-GTAAHAAERMFGLLVA 318
Cdd:pfam05045  423 NAEVMKDLAERLGiKVPFDDFK-EPVAplGTMFWFRPKALKPLFDLDWKYEDFPAEPLKPdGTILHAIERLYGYAAQ 498
Glycos_transf_2 pfam00535
Glycosyl transferase family 2; Diverse family, transferring sugar from UDP-glucose, ...
 763-864 3.10e-08

Glycosyl transferase family 2; Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.


Pssm-ID: 425738 [Multi-domain]  Cd Length: 166  Bit Score: 54.32  E-value: 3.10e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572   763 VIIPNWQSLDEINECLDALTAKDWKGqLKIIVIDNASDRDVVNYLVD-REAAGDIDLIQNKRNYGFTYAVNQGIRraHAG 841
Cdd:pfam00535    2 VIIPTYNEEKYLLETLESLLNQTYPN-FEIIVVDDGSTDGTVEIAEEyAKKDPRVRVIRLPENRGKAGARNAGLR--AAT 78

                           90       100
                   ....*....|....*....|....
gi 490176572   842 AD-ILVLNNDAVVRKGAIQALQKA 864
Cdd:pfam00535   79 GDyIAFLDADDEVPPDWLEKLVEA 102
EPS_HpsE NF038302
hormogonium polysaccharide biosynthesis glycosyltransferase HpsE;
551-623 5.98e-05

hormogonium polysaccharide biosynthesis glycosyltransferase HpsE;


Pssm-ID: 439602 [Multi-domain]  Cd Length: 307  Bit Score: 46.33  E-value: 5.98e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  551 ELIVVDDCSTDATESAVQAF---HDDRIRLITLPE-NKGPSAARNAGLQVAQGEILAYLDSDNTWDDRYLAAI------- 619
Cdd:NF038302   35 EIIVVDNNSTDNTAQVVQEYqknWPSPYPLRYCFEpQQGAAFARQRAIQEAKGELIGFLDDDNLPAPNWVAAAyafgqeh 114


                  ....*.
gi 490176572  620 --AGAF 623
Cdd:NF038302  115 pqAGAY 120
 
Name Accession Description Interval E-value
WcaA COG0463
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ...
 519-710 4.33e-40

Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440231 [Multi-domain]  Cd Length: 208  Bit Score: 147.16  E-value: 4.33e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  519 KPLISVIMPVYNRVAIVGEAIASVLAQSYHYFELIVVDDCSTDATESAVQAF--HDDRIRLITLPENKGPSAARNAGLQV 596
Cdd:COG0463     1 MPLVSVVIPTYNEEEYLEEALESLLAQTYPDFEIIVVDDGSTDGTAEILRELaaKDPRIRVIRLERNRGKGAARNAGLAA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  597 AQGEILAYLDSDNTWDDRYLAAIAGAFETLPdADAVYSGILLYRNRDSSPFAVRYGHYHRALLENRNYIDMNIFSHRRGL 676
Cdd:COG0463    81 ARGDYIAFLDADDQLDPEKLEELVAALEEGP-ADLVYGSRLIREGESDLRRLGSRLFNLVRLLTNLPDSTSGFRLFRREV 159

                         170       180       190
                  ....*....|....*....|....*....|....
gi 490176572  677 MDRMsGFDQNMkrYVDYDFILRASESGTVYSVPI 710
Cdd:COG0463   160 LEEL-GFDEGF--LEDTELLRALRHGFRIAEVPV 190
GT2_RfbC_Mx_like cd04184
Myxococcus xanthus RfbC like proteins are required for O-antigen biosynthesis; The rfbC gene ...
 520-714 2.47e-34

Myxococcus xanthus RfbC like proteins are required for O-antigen biosynthesis; The rfbC gene encodes a predicted protein of 1,276 amino acids, which is required for O-antigen biosynthesis in Myxococcus xanthus. It is a subfamily of Glycosyltransferase Family GT2, which includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds.


Pssm-ID: 133027 [Multi-domain]  Cd Length: 202  Bit Score: 130.40  E-value: 2.47e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  520 PLISVIMPVYNR-VAIVGEAIASVLAQSYHYFELIVVDDCSTDA-TESAVQAF--HDDRIRLITLPENKGPSAARNAGLQ 595
Cdd:cd04184     1 PLISIVMPVYNTpEKYLREAIESVRAQTYPNWELCIADDASTDPeVKRVLKKYaaQDPRIKVVFREENGGISAATNSALE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  596 VAQGEILAYLDSDNTWDDRYLAAIAGAFETLPDADAVYSgillyrNRDS-SPFAVRYGHYHR-----ALLENRNYIDmNI 669
Cdd:cd04184    81 LATGEFVALLDHDDELAPHALYEVVKALNEHPDADLIYS------DEDKiDEGGKRSEPFFKpdwspDLLLSQNYIG-HL 153

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 490176572  670 FSHRRGLMDRMSGFDQNMKRYVDYDFILRASESGT-VYSVPILLCR 714
Cdd:cd04184   154 LVYRRSLVRQVGGFREGFEGAQDYDLVLRVSEHTDrIAHIPRVLYH 199
GT_2_WfgS_like cd06433
WfgS and WfeV are involved in O-antigen biosynthesis; Escherichia coli WfgS and Shigella ...
 523-717 1.87e-33

WfgS and WfeV are involved in O-antigen biosynthesis; Escherichia coli WfgS and Shigella dysenteriae WfeV are glycosyltransferase 2 family enzymes involved in O-antigen biosynthesis. GT-2 enzymes have GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.


Pssm-ID: 133055 [Multi-domain]  Cd Length: 202  Bit Score: 128.05  E-value: 1.87e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  523 SVIMPVYNRVAIVGEAIASVLAQSYHYFELIVVDDCSTDATESAVQAFHDDRIRLITLPEnKGPSAARNAGLQVAQGEIL 602
Cdd:cd06433     1 SIITPTYNQAETLEETIDSVLSQTYPNIEYIVIDGGSTDGTVDIIKKYEDKITYWISEPD-KGIYDAMNKGIALATGDII 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  603 AYLDSDNTWDDRYLAAIAGAFETLPDADAVYSGILLYRNRDSSPFAVRYGHYHRALLENRNYID-MNIFsHRRGLMDRMS 681
Cdd:cd06433    80 GFLNSDDTLLPGALLAVVAAFAEHPEVDVVYGDVLLVDENGRVIGRRRPPPFLDKFLLYGMPIChQATF-FRRSLFEKYG 158

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 490176572  682 GFDQNMKRYVDYDFILRASESGTVYS-VPILLCRYNY 717
Cdd:cd06433   159 GFDESYRIAADYDLLLRLLLAGKIFKyLPEVLAAFRL 195
Glyco_tranf_GTA_type cd00761
Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a ...
 524-677 2.93e-33

Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.


Pssm-ID: 132997 [Multi-domain]  Cd Length: 156  Bit Score: 125.70  E-value: 2.93e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  524 VIMPVYNRVAIVGEAIASVLAQSYHYFELIVVDDCSTDATESAVQAFH--DDRIRLITLPENKGPSAARNAGLQVAQGEI 601
Cdd:cd00761     1 VIIPAYNEEPYLERCLESLLAQTYPNFEVIVVDDGSTDGTLEILEEYAkkDPRVIRVINEENQGLAAARNAGLKAARGEY 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 490176572  602 LAYLDSDNTWDDRYLAAIAGAFETLPDADAVYS-GILLYRNrdssPFAVRYGHYHRALLENRNYIDMNIFSHRRGLM 677
Cdd:cd00761    81 ILFLDADDLLLPDWLERLVAELLADPEADAVGGpGNLLFRR----ELLEEIGGFDEALLSGEEDDDFLLRLLRGGKV 153
Glycos_transf_2 pfam00535
Glycosyl transferase family 2; Diverse family, transferring sugar from UDP-glucose, ...
 523-670 3.38e-32

Glycosyl transferase family 2; Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.


Pssm-ID: 425738 [Multi-domain]  Cd Length: 166  Bit Score: 123.27  E-value: 3.38e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572   523 SVIMPVYNRVAIVGEAIASVLAQSYHYFELIVVDDCSTDATESAVQAFH--DDRIRLITLPENKGPSAARNAGLQVAQGE 600
Cdd:pfam00535    1 SVIIPTYNEEKYLLETLESLLNQTYPNFEIIVVDDGSTDGTVEIAEEYAkkDPRVRVIRLPENRGKAGARNAGLRAATGD 80

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572   601 ILAYLDSDNTWDDRYLAAIAGAFETLPDADAVYSGILLYRNRDSSPFAVRYGHYHRALLENRNYIDMNIF 670
Cdd:pfam00535   81 YIAFLDADDEVPPDWLEKLVEALEEDGADVVVGSRYVIFGETGEYRRASRITLSRLPFFLGLRLLGLNLP 150
WcaE COG1216
Glycosyltransferase, GT2 family [Carbohydrate transport and metabolism];
518-709 1.15e-30

Glycosyltransferase, GT2 family [Carbohydrate transport and metabolism];


Pssm-ID: 440829 [Multi-domain]  Cd Length: 202  Bit Score: 120.10  E-value: 1.15e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  518 SKPLISVIMPVYNRVAIVGEAIASVLAQSYHYFELIVVDDCSTDATESAVQAFHDDRIRLITLPENKGPSAARNAGLQVA 597
Cdd:COG1216     1 MRPKVSVVIPTYNRPELLRRCLESLLAQTYPPFEVIVVDNGSTDGTAELLAALAFPRVRVIRNPENLGFAAARNLGLRAA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  598 QGEILAYLDSDNTWDDRYLAAIAGAfetlpdadavySGILLyrnrdsspfavryghyhrallenrnyidmnifshRRGLM 677
Cdd:COG1216    81 GGDYLLFLDDDTVVEPDWLERLLAA-----------ACLLI----------------------------------RREVF 115

                         170       180       190
                  ....*....|....*....|....*....|....
gi 490176572  678 DRMSGFDQNMKRY-VDYDFILRASESG-TVYSVP 709
Cdd:COG1216   116 EEVGGFDERFFLYgEDVDLCLRLRKAGyRIVYVP 149
BcsA COG1215
Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1, ...
 517-632 5.79e-29

Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility];


Pssm-ID: 440828 [Multi-domain]  Cd Length: 303  Bit Score: 118.31  E-value: 5.79e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  517 ESKPLISVIMPVYNRVAIVGEAIASVLAQSY--HYFELIVVDDCSTDATESAVQAF--HDDRIRLITLPENKGPSAARNA 592
Cdd:COG1215    26 ADLPRVSVIIPAYNEEAVIEETLRSLLAQDYpkEKLEVIVVDDGSTDETAEIARELaaEYPRVRVIERPENGGKAAALNA 105

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 490176572  593 GLQVAQGEILAYLDSDNTWDDRYLAAIAGAFETlPDADAV 632
Cdd:COG1215   106 GLKAARGDIVVFLDADTVLDPDWLRRLVAAFAD-PGVGAS 144
Succinoglycan_BP_ExoA cd02525
ExoA is involved in the biosynthesis of succinoglycan; Succinoglycan Biosynthesis Protein ExoA ...
 521-715 3.72e-24

ExoA is involved in the biosynthesis of succinoglycan; Succinoglycan Biosynthesis Protein ExoA catalyzes the formation of a beta-1,3 linkage of the second sugar (glucose) of the succinoglycan with the galactose on the lipid carrie. Succinoglycan is an acidic exopolysaccharide that is important for invasion of the nodules. Succinoglycan is a high-molecular-weight polymer composed of repeating octasaccharide units. These units are synthesized on membrane-bound isoprenoid lipid carriers, beginning with galactose followed by seven glucose molecules, and modified by the addition of acetate, succinate, and pyruvate. ExoA is a membrane protein with a transmembrance domain at c-terminus.


Pssm-ID: 133016 [Multi-domain]  Cd Length: 249  Bit Score: 102.70  E-value: 3.72e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  521 LISVIMPVYNRVAIVGEAIASVLAQSYHY--FELIVVDDCSTDATESAVQAF--HDDRIRLItlpENKG--PSAARNAGL 594
Cdd:cd02525     1 FVSIIIPVRNEEKYIEELLESLLNQSYPKdlIEIIVVDGGSTDGTREIVQEYaaKDPRIRLI---DNPKriQSAGLNIGI 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  595 QVAQGEILAYLDSDNTWDDRYLAAIAGAFETlPDADAVySGILLYRNRD----------SSPFAVRyGHYHRALLENRNY 664
Cdd:cd02525    78 RNSRGDIIIRVDAHAVYPKDYILELVEALKR-TGADNV-GGPMETIGESkfqkaiavaqSSPLGSG-GSAYRGGAVKIGY 154

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 490176572  665 IDMNIFS-HRRGLMDRMSGFDQNMKRYVDYDFILRASESG-TVYSVPILLCRY 715
Cdd:cd02525   155 VDTVHHGaYRREVFEKVGGFDESLVRNEDAELNYRLRKAGyKIWLSPDIRVYY 207
WcaE COG1216
Glycosyltransferase, GT2 family [Carbohydrate transport and metabolism];
761-992 2.21e-23

Glycosyltransferase, GT2 family [Carbohydrate transport and metabolism];


Pssm-ID: 440829 [Multi-domain]  Cd Length: 202  Bit Score: 98.91  E-value: 2.21e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  761 VAVIIPNWQSLDEINECLDALTAKDWkGQLKIIVIDNASDRDVVNYLvDREAAGDIDLIQNKRNYGFTYAVNQGIRraHA 840
Cdd:COG1216     5 VSVVIPTYNRPELLRRCLESLLAQTY-PPFEVIVVDNGSTDGTAELL-AALAFPRVRVIRNPENLGFAAARNLGLR--AA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  841 GAD-ILVLNNDAVVRKGAIQALQKACyslphagmtvprqilpagtktfqthvpfasedydcdvnisahhrniarvpvfhn 919
Cdd:COG1216    81 GGDyLLFLDDDTVVEPDWLERLLAAA------------------------------------------------------ 106

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 490176572  920 gknlelsfapffAVYIQRDLIARIGVLDAEYGrHYRSDRVYCDMARNVGGkKIYYVPDAFVIHKLQKATDSLR 992
Cdd:COG1216   107 ------------CLLIRREVFEEVGGFDERFF-LYGEDVDLCLRLRKAGY-RIVYVPDAVVYHLGGASSGPLL 165
CESA_like cd06423
CESA_like is the cellulose synthase superfamily; The cellulose synthase (CESA) superfamily ...
 524-648 1.37e-22

CESA_like is the cellulose synthase superfamily; The cellulose synthase (CESA) superfamily includes a wide variety of glycosyltransferase family 2 enzymes that share the common characteristic of catalyzing the elongation of polysaccharide chains. The members include cellulose synthase catalytic subunit, chitin synthase, glucan biosynthesis protein and other families of CESA-like proteins. Cellulose synthase catalyzes the polymerization reaction of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues in plants, most algae, some bacteria and fungi, and even some animals. In bacteria, algae and lower eukaryotes, there is a second unrelated type of cellulose synthase (Type II), which produces acylated cellulose, a derivative of cellulose. Chitin synthase catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin, which is a linear homopolymer of beta-(1,4)-linked GlcNAc residues and Glucan Biosynthesis protein catalyzes the elongation of beta-1,2 polyglucose chains of Glucan.


Pssm-ID: 133045 [Multi-domain]  Cd Length: 180  Bit Score: 96.14  E-value: 1.37e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  524 VIMPVYNRVAIVGEAIASVLAQSYHYFELIVVDDCSTDATESAVQAF---HDDRIRLITLPENKGPSAARNAGLQVAQGE 600
Cdd:cd06423     1 IIVPAYNEEAVIERTIESLLALDYPKLEVIVVDDGSTDDTLEILEELaalYIRRVLVVRDKENGGKAGALNAGLRHAKGD 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 490176572  601 ILAYLDSDNTWDDRYLAAIAGAFETLPDADAVySGILLYRNRDSSPFA 648
Cdd:cd06423    81 IVVVLDADTILEPDALKRLVVPFFADPKVGAV-QGRVRVRNGSENLLT 127
CESA_like_1 cd06439
CESA_like_1 is a member of the cellulose synthase (CESA) superfamily; This is a subfamily of ...
 517-654 7.94e-22

CESA_like_1 is a member of the cellulose synthase (CESA) superfamily; This is a subfamily of cellulose synthase (CESA) superfamily. CESA superfamily includes a wide variety of glycosyltransferase family 2 enzymes that share the common characteristic of catalyzing the elongation of polysaccharide chains. The members of the superfamily include cellulose synthase catalytic subunit, chitin synthase, glucan biosynthesis protein and other families of CESA-like proteins.


Pssm-ID: 133061 [Multi-domain]  Cd Length: 251  Bit Score: 96.11  E-value: 7.94e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  517 ESKPLISVIMPVYNRVAIVGEAIASVLAQSY--HYFELIVVDDCSTDATESAVQAFHDDRIRLITLPENKGPSAARNAGL 594
Cdd:cd06439    26 AYLPTVTIIIPAYNEEAVIEAKLENLLALDYprDRLEIIVVSDGSTDGTAEIAREYADKGVKLLRFPERRGKAAALNRAL 105

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  595 QVAQGEILAYLDSDNTWDDRYLAAIAGAFeTLPDADAVySGILLYRNRDSSPFAVryGHY 654
Cdd:cd06439   106 ALATGEIVVFTDANALLDPDALRLLVRHF-ADPSVGAV-SGELVIVDGGGSGSGE--GLY 161
mycofact_glyco TIGR03965
mycofactocin system glycosyltransferase; Members of this protein family are putative ...
 494-703 7.70e-21

mycofactocin system glycosyltransferase; Members of this protein family are putative glycosyltransferases, members of pfam00535 (glycosyl transferase family 2). Members appear mostly in the Actinobacteria, where they appear to be part of a system for converting a precursor peptide (TIGR03969) into a novel redox carrier designated mycofactocin. A radical SAM enzyme, TIGR03962, is a proposed to be a key maturase for mycofactocin.


Pssm-ID: 274884 [Multi-domain]  Cd Length: 466  Bit Score: 97.14  E-value: 7.70e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572   494 ADKRSLAVMEGIANRFCA--IAGKLESKPLISVIMPVYNRVAIVGEAIASVLAQSYH--YFELIVVDDCSTDATESAVQA 569
Cdd:TIGR03965   46 RDETSAALLRRLLDSGVVhpRPALLPSPPSVTVVVPVRNRPAGLARLLAALLALDYPrdRLEVIVVDDGSEDPVPTRAAR 125

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572   570 FHDDRIRLITLPENKGPSAARNAGLQVAQGEILAYLDSDNTWDDRYLAAIAGAFETlPDADAVYSGILLYRNRDsSPFAv 649
Cdd:TIGR03965  126 GARLPVRVIRHPRRQGPAAARNAGARAARTEFVAFTDSDVVPRPGWLRALLAHFDD-PGVALVAPRVVALPAAD-TRLA- 202

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 490176572   650 RYGHYHRALLENRN-----------YIDMNIFSHRRGLMDRMSGFDQNMKRYVDYDFILRASESG 703
Cdd:TIGR03965  203 RYEAVRSSLDLGPEeavvrprgpvsYVPSAALLVRRRALLEVGGFDERLEVGEDVDLCWRLCEAG 267
GT_2_like_c cd04186
Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse ...
 763-983 2.59e-20

Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.


Pssm-ID: 133029 [Multi-domain]  Cd Length: 166  Bit Score: 89.16  E-value: 2.59e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  763 VIIPNWQSLDEINECLDALTAKDwKGQLKIIVIDNASDRDVVNYLvdREAAGDIDLIQNKRNYGFTYAVNQGIRraHAGA 842
Cdd:cd04186     1 IIIVNYNSLEYLKACLDSLLAQT-YPDFEVIVVDNASTDGSVELL--RELFPEVRLIRNGENLGFGAGNNQGIR--EAKG 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  843 D-ILVLNNDAVVRKGAIQALQKACYSLPHAGMTVPRqiLPAGtktfqthvpfasedydcdvnisahhrniarvpvfhngk 921
Cdd:cd04186    76 DyVLLLNPDTVVEPGALLELLDAAEQDPDVGIVGPK--VSGA-------------------------------------- 115

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 490176572  922 nlelsfapffAVYIQRDLIARIGVLDAEYgRHYRSDRVYCDMARNvGGKKIYYVPDAFVIHK 983
Cdd:cd04186   116 ----------FLLVRREVFEEVGGFDEDF-FLYYEDVDLCLRARL-AGYRVLYVPQAVIYHH 165
PRK10018 PRK10018
colanic acid biosynthesis glycosyltransferase WcaA;
519-740 6.88e-20

colanic acid biosynthesis glycosyltransferase WcaA;


Pssm-ID: 182197 [Multi-domain]  Cd Length: 279  Bit Score: 91.21  E-value: 6.88e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  519 KPLISVIMPVYNRVAIVGEAIASVLAQSYHYFELIVVDDCST--DATESAVQAFHDDRIRLITLPENKGPSAARNAGLQV 596
Cdd:PRK10018    4 NPLISIYMPTWNRQQLAIRAIKSVLRQDYSNWEMIIVDDCSTswEQLQQYVTALNDPRITYIHNDINSGACAVRNQAIML 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  597 AQGEILAYLDSDNTWDDRYLAAIAGAFETLPDADAVYSGILL-----YRNRDSSPFAVRyGHYHRALLENRNYIDMNIFS 671
Cdd:PRK10018   84 AQGEYITGIDDDDEWTPNRLSVFLAHKQQLVTHAFLYANDYVcqgevYSQPASLPLYPK-SPYSRRLFYKRNIIGNQVFT 162

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 490176572  672 HRRGLMDRMsgFDQNMKRYVDYDFILR-ASESGTVYSVPILLCRYNYNKADNTVTADP-RYESHLNPIHKH 740
Cdd:PRK10018  163 WAWRFKECL--FDTELKAAQDYDIFLRmVVEYGEPWKVEEATQILHINHGEMQITSSPkKFSGYFHFYRKH 231
DPM_DPG-synthase_like cd04179
DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; DPM1 is the ...
 524-683 7.11e-19

DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; DPM1 is the catalytic subunit of eukaryotic dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. In higher eukaryotes,the enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. In lower eukaryotes, such as Saccharomyces cerevisiae and Trypanosoma brucei, DPM synthase consists of a single component (Dpm1p and TbDpm1, respectively) that possesses one predicted transmembrane region near the C terminus for anchoring to the ER membrane. In contrast, the Dpm1 homologues of higher eukaryotes, namely fission yeast, fungi, and animals, have no transmembrane region, suggesting the existence of adapter molecules for membrane anchoring. This family also includes bacteria and archaea DPM1_like enzymes. However, the enzyme structure and mechanism of function are not well understood. The UDP-glucose:dolichyl-phosphate glucosyltransferase (DPG_synthase) is a transmembrane-bound enzyme of the endoplasmic reticulum involved in protein N-linked glycosylation. This enzyme catalyzes the transfer of glucose from UDP-glucose to dolichyl phosphate. This protein family belongs to Glycosyltransferase 2 superfamily.


Pssm-ID: 133022 [Multi-domain]  Cd Length: 185  Bit Score: 85.32  E-value: 7.11e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  524 VIMPVYN---RVAIVGEAIASVLAQSYHYfELIVVDDCSTDATESAVQAF--HDDRIRLITLPENKGPSAARNAGLQVAQ 598
Cdd:cd04179     1 VVIPAYNeeeNIPELVERLLAVLEEGYDY-EIIVVDDGSTDGTAEIARELaaRVPRVRVIRLSRNFGKGAAVRAGFKAAR 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  599 GEILAYLDSDNTWD----DRYLAAIAgafetLPDADAVYSgillyrNRDSSPFAVRYGHYHRALleNR-NYIDMNIFSHR 673
Cdd:cd04179    80 GDIVVTMDADLQHPpediPKLLEKLL-----EGGADVVIG------SRFVRGGGAGMPLLRRLG--SRlFNFLIRLLLGV 146

                         170
                  ....*....|
gi 490176572  674 RgLMDRMSGF 683
Cdd:cd04179   147 R-ISDTQSGF 155
RgpF pfam05045
Rhamnan synthesis protein F; This family consists of a group of proteins which are related to ...
 101-318 1.17e-17

Rhamnan synthesis protein F; This family consists of a group of proteins which are related to the Streptococcus rhamnose-glucose polysaccharide assembly protein (RgpF). Rhamnan backbones are found in several O polysaccharides of phytopathogenic bacteria and are regarded as pathogenic factors.


Pssm-ID: 428278  Cd Length: 500  Bit Score: 87.39  E-value: 1.17e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572   101 RYALVIHVFYLDILGDLKASAAHFPESGDIFVTCPDSFSRIECDDIRSFFPR-AEIIQVPNVNQDVGALmgLMAQVDF-R 178
Cdd:pfam05045  270 RIAVHLHVYYEDLLEEFLHYFKSFPFEYDLYITTDSEEKKKLIKEILKELSYkAKVRLVGNRGRDVSPF--LVGLKDElM 347

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572   179 DYGFICKIHSKKGNKCP-----EKWRRALLDGVLGSKAQVERTIRLFQSDDELMIggakqLFLHGPS--------NLWKN 245
Cdd:pfam05045  348 KYDYICHFHDKKSTQASpysvgDSFRYECFDNLLKSKGYVDNIIATFEQNPRLGI-----LIPPPPNhgryntivDEWNE 422

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 490176572   246 KALISNVFGPFLG-DFDFERADwGFFA--GTCFWIRTSILCKIKEHMDGLENRPGAYVDG-GTAAHAAERMFGLLVA 318
Cdd:pfam05045  423 NAEVMKDLAERLGiKVPFDDFK-EPVAplGTMFWFRPKALKPLFDLDWKYEDFPAEPLKPdGTILHAIERLYGYAAQ 498
GT_2_like_d cd04196
Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse ...
 523-634 4.93e-17

Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.


Pssm-ID: 133039 [Multi-domain]  Cd Length: 214  Bit Score: 81.14  E-value: 4.93e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  523 SVIMPVYNrvaivGEA-----IASVLAQSYHYFELIVVDDCSTDATESAVQAF---HDDRIRLITLPENKGPsaARN--A 592
Cdd:cd04196     1 AVLMATYN-----GEKylreqLDSILAQTYKNDELIISDDGSTDGTVEIIKEYidkDPFIIILIRNGKNLGV--ARNfeS 73

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 490176572  593 GLQVAQGEILAYLDSDNTWDDRYLAAIAGAFETLPDADAVYS 634
Cdd:cd04196    74 LLQAADGDYVFFCDQDDIWLPDKLERLLKAFLKDDKPLLVYS 115
PRK10073 PRK10073
putative glycosyl transferase; Provisional
 518-610 5.92e-16

putative glycosyl transferase; Provisional


Pssm-ID: 182223 [Multi-domain]  Cd Length: 328  Bit Score: 80.09  E-value: 5.92e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  518 SKPLISVIMPVYNRVAIVGEAIASVLAQSYHYFELIVVDDCSTDATESAVQ--AFHDDRIRLITlPENKGPSAARNAGLQ 595
Cdd:PRK10073    4 STPKLSIIIPLYNAGKDFRAFMESLIAQTWTALEIIIVNDGSTDNSVEIAKhyAENYPHVRLLH-QANAGVSVARNTGLA 82

                          90
                  ....*....|....*
gi 490176572  596 VAQGEILAYLDSDNT 610
Cdd:PRK10073   83 VATGKYVAFPDADDV 97
GT_2_like_c cd04186
Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse ...
 524-632 7.02e-16

Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.


Pssm-ID: 133029 [Multi-domain]  Cd Length: 166  Bit Score: 76.06  E-value: 7.02e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  524 VIMPVYNRVAIVGEAIASVLAQSYHYFELIVVDDCSTDATESAVQAfHDDRIRLITLPENKGPSAARNAGLQVAQGEILA 603
Cdd:cd04186     1 IIIVNYNSLEYLKACLDSLLAQTYPDFEVIVVDNASTDGSVELLRE-LFPEVRLIRNGENLGFGAGNNQGIREAKGDYVL 79

                          90       100
                  ....*....|....*....|....*....
gi 490176572  604 YLDSDNTWDDRYLAAIAGAFETLPDADAV 632
Cdd:cd04186    80 LLNPDTVVEPGALLELLDAAEQDPDVGIV 108
Glyco_tranf_2_3 pfam13641
Glycosyltransferase like family 2; Members of this family of prokaryotic proteins include ...
 520-682 1.86e-15

Glycosyltransferase like family 2; Members of this family of prokaryotic proteins include putative glucosyltransferase, which are involved in bacterial capsule biosynthesis.


Pssm-ID: 433372 [Multi-domain]  Cd Length: 230  Bit Score: 76.64  E-value: 1.86e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572   520 PLISVIMPVYNRVAIVGEAIASVLAQSYHYFELIVVDDCSTDAT----ESAVQAFHDDRIRLITLPENKGP---SAARNA 592
Cdd:pfam13641    2 PDVSVVVPAFNEDSVLGRVLEAILAQPYPPVEVVVVVNPSDAETldvaEEIAARFPDVRLRVIRNARLLGPtgkSRGLNH 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572   593 GLQVAQGEILAYLDSDNTWDDRYLAAIAGAFETlPDADAVYsGILLYRNRDSSPFAVRYGHYhralleNRNYIDMNIFSH 672
Cdd:pfam13641   82 GFRAVKSDLVVLHDDDSVLHPGTLKKYVQYFDS-PKVGAVG-TPVFSLNRSTMLSALGALEF------ALRHLRMMSLRL 153

                          170
                   ....*....|
gi 490176572   673 RRGLMDrMSG 682
Cdd:pfam13641  154 ALGVLP-LSG 162
DPM1_like_bac cd04187
Bacterial DPM1_like enzymes are related to eukaryotic DPM1; A family of bacterial enzymes ...
 524-608 2.59e-14

Bacterial DPM1_like enzymes are related to eukaryotic DPM1; A family of bacterial enzymes related to eukaryotic DPM1; Although the mechanism of eukaryotic enzyme is well studied, the mechanism of the bacterial enzymes is not well understood. The eukaryotic DPM1 is the catalytic subunit of eukaryotic Dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. The enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. This protein family belongs to Glycosyltransferase 2 superfamily.


Pssm-ID: 133030 [Multi-domain]  Cd Length: 181  Bit Score: 72.12  E-value: 2.59e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  524 VIMPVYNRVAIVGE---AIASVLAQSYHYFELIVVDDCSTDATESAVQ--AFHDDRIRLITLPENKGPSAARNAGLQVAQ 598
Cdd:cd04187     1 IVVPVYNEEENLPElyeRLKAVLESLGYDYEIIFVDDGSTDRTLEILRelAARDPRVKVIRLSRNFGQQAALLAGLDHAR 80

                          90
                  ....*....|
gi 490176572  599 GEILAYLDSD 608
Cdd:cd04187    81 GDAVITMDAD 90
GT_2_like_a cd02522
GT_2_like_a represents a glycosyltransferase family-2 subfamily with unknown function; ...
 522-710 5.37e-13

GT_2_like_a represents a glycosyltransferase family-2 subfamily with unknown function; Glycosyltransferase family 2 (GT-2) subfamily of unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.


Pssm-ID: 133013 [Multi-domain]  Cd Length: 221  Bit Score: 69.52  E-value: 5.37e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  522 ISVIMPVYNRVAIVGEAIASVLAQSYHYFELIVVDDCSTDATESAVQAFHddrIRLITlpENKGPSAARNAGLQVAQGEI 601
Cdd:cd02522     1 LSIIIPTLNEAENLPRLLASLRRLNPLPLEIIVVDGGSTDGTVAIARSAG---VVVIS--SPKGRARQMNAGAAAARGDW 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  602 LAYLDSDNTWDDRYLAAIagAFETLPDADAVYSGILLYRNRDSSPFAVRYGHYHRALLENRNYIDMNIFSHRRgLMDRMS 681
Cdd:cd02522    76 LLFLHADTRLPPDWDAAI--IETLRADGAVAGAFRLRFDDPGPRLRLLELGANLRSRLFGLPYGDQGLFIRRE-LFEELG 152

                         170       180       190
                  ....*....|....*....|....*....|.
gi 490176572  682 GFDQnmkRYV--DYDFILRASESGTVYSVPI 710
Cdd:cd02522   153 GFPE---LPLmeDVELVRRLRRRGRPALLPS 180
PLN02726 PLN02726
dolichyl-phosphate beta-D-mannosyltransferase
 515-632 3.07e-12

dolichyl-phosphate beta-D-mannosyltransferase


Pssm-ID: 215385 [Multi-domain]  Cd Length: 243  Bit Score: 67.80  E-value: 3.07e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  515 KLESKPLISVIMPVYNR---VAIVGEAIASVLaQSYHYFELIVVDDCSTDATESAV----QAFHDDRIRLITLPENKGPS 587
Cdd:PLN02726    4 PGEGAMKYSIIVPTYNErlnIALIVYLIFKAL-QDVKDFEIIVVDDGSPDGTQDVVkqlqKVYGEDRILLRPRPGKLGLG 82

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 490176572  588 AARNAGLQVAQGEILAYLDSDNTWDDRYLAA-IAGAFETlpDADAV 632
Cdd:PLN02726   83 TAYIHGLKHASGDFVVIMDADLSHHPKYLPSfIKKQRET--GADIV 126
glyco_like_mftF TIGR04283
transferase 2, rSAM/selenodomain-associated; This enzyme may transfer a nucleotide, or it ...
 522-752 6.84e-12

transferase 2, rSAM/selenodomain-associated; This enzyme may transfer a nucleotide, or it sugar moiety, as part of a biosynthetic pathway. Other proposed members of the pathway include another transferase (TIGR04282), a phosphoesterase, and a radical SAM enzyme (TIGR04167) whose C-terminal domain (pfam12345) frequently contains a selenocysteine. [Unknown function, Enzymes of unknown specificity]


Pssm-ID: 275103 [Multi-domain]  Cd Length: 220  Bit Score: 66.00  E-value: 6.84e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572   522 ISVIMPVYNRVAIVGEAIASVLAQSYHyFELIVVDDCSTDATESAVQAFHDdriRLITLPenKGPSAARNAGLQVAQGEI 601
Cdd:TIGR04283    1 LSIIIPVLNEAATLPELLADLQALRGD-AEVIVVDGGSTDGTVEIARSLGA---KVIHSP--KGRARQMNAGAALAKGDI 74

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572   602 LAYLDSDNTWDDRYLAAIAGAFetlpDADAVYSGILLYRNRDSSPFA--VRYGHYHRALLENRNYIDMNIFSHRRgLMDR 679
Cdd:TIGR04283   75 LLFLHADTRLPKDFLEAIRRAL----AKPGYVAGAFDLRFDGPGLLLrlIEWGVNLRSRLTGIPYGDQGLFVRRS-LFEQ 149

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 490176572   680 MSGFdQNMKRYVDYDFILRASESGTVYSVPillcrynynkaDNTVTADPRYESH--LNPIHKHLQARNAARLEAS 752
Cdd:TIGR04283  150 IGGF-PDIPLMEDIELSRRLRRLGRLAILP-----------APVVTSARRWEKNgiLRTILLNWRLRLLYRLGVS 212
GT_2_like_b cd04185
Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse ...
 529-597 8.88e-12

Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.


Pssm-ID: 133028 [Multi-domain]  Cd Length: 202  Bit Score: 65.35  E-value: 8.88e-12
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  529 YNRVAIVGEAIASVLAQSYHYFELIVVDDCSTDATESAVQAFHD-DRIRLITLPENKGPSAARNAGLQVA 597
Cdd:cd04185     6 YNRLDLLKECLDALLAQTRPPDHIIVIDNASTDGTAEWLTSLGDlDNIVYLRLPENLGGAGGFYEGVRRA 75
DPG_synthase cd04188
DPG_synthase is involved in protein N-linked glycosylation; UDP-glucose:dolichyl-phosphate ...
 524-609 6.02e-11

DPG_synthase is involved in protein N-linked glycosylation; UDP-glucose:dolichyl-phosphate glucosyltransferase (DPG_synthase) is a transmembrane-bound enzyme of the endoplasmic reticulum involved in protein N-linked glycosylation. This enzyme catalyzes the transfer of glucose from UDP-glucose to dolichyl phosphate.


Pssm-ID: 133031 [Multi-domain]  Cd Length: 211  Bit Score: 62.97  E-value: 6.02e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  524 VIMPVYN---RVAIVGEAIASVLAQSYHY-FELIVVDDCSTDATESAVQAF---HDDRIRLITLPENKGPSAARNAGLQV 596
Cdd:cd04188     1 VVIPAYNeekRLPPTLEEAVEYLEERPSFsYEIIVVDDGSKDGTAEVARKLarkNPALIRVLTLPKNRGKGGAVRAGMLA 80

                          90
                  ....*....|...
gi 490176572  597 AQGEILAYLDSDN 609
Cdd:cd04188    81 ARGDYILFADADL 93
Glyco_tranf_2_2 pfam10111
Glycosyltransferase like family 2; Members of this family of prokaryotic proteins include ...
 523-698 1.10e-10

Glycosyltransferase like family 2; Members of this family of prokaryotic proteins include putative glucosyltransferase, which are involved in bacterial capsule biosynthesis.


Pssm-ID: 313356 [Multi-domain]  Cd Length: 276  Bit Score: 63.45  E-value: 1.10e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572   523 SVIMPVYN--RVAIVGEAIASVLAQSYHYFELIVVDDCSTDATESAVQAFHDDRIrLITLPE----NKGPSAARNAGLQV 596
Cdd:pfam10111    1 SVVIPVYNgeKTHWIQERILNQTFQYDPEFELIIINDGSTDKTLEEVSSIKDHNL-QVYYPNapdtTYSLAASRNRGTSH 79

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572   597 AQGEILAYLDSDNTWDDRYLAAIA-----GAFETLPDADAVYSgiLLYRNRDSSPFAVRYGH------YHRALLENRNYI 665
Cdd:pfam10111   80 AIGEYISFIDGDCLWSPDKFEKQLkiatsLALQENIQAAVVLP--VTDLNDESSNFLRRGGDltasgdVLRDLLVFYSPL 157

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|.
gi 490176572   666 DM------NIFSHRRGLMDRMSGFDQNMKR--YVDYDFILR 698
Cdd:pfam10111  158 AIffapnsSNALINRQAFIEVGGFDESFRGhgAEDFDIFLR 198
pp-GalNAc-T cd02510
pp-GalNAc-T initiates the formation of mucin-type O-linked glycans; UDP-GalNAc: polypeptide ...
 523-607 2.67e-09

pp-GalNAc-T initiates the formation of mucin-type O-linked glycans; UDP-GalNAc: polypeptide alpha-N-acetylgalactosaminyltransferases (pp-GalNAc-T) initiate the formation of mucin-type, O-linked glycans by catalyzing the transfer of alpha-N-acetylgalactosamine (GalNAc) from UDP-GalNAc to hydroxyl groups of Ser or Thr residues of core proteins to form the Tn antigen (GalNAc-a-1-O-Ser/Thr). These enzymes are type II membrane proteins with a GT-A type catalytic domain and a lectin domain located on the lumen side of the Golgi apparatus. In human, there are 15 isozymes of pp-GalNAc-Ts, representing the largest of all glycosyltransferase families. Each isozyme has unique but partially redundant substrate specificity for glycosylation sites on acceptor proteins.


Pssm-ID: 133004 [Multi-domain]  Cd Length: 299  Bit Score: 59.53  E-value: 2.67e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  523 SVIMPVYNrvaivgEA-------IASVLAQS--YHYFELIVVDDCSTDAT-----ESAVQAFHDdRIRLITLPENKGPSA 588
Cdd:cd02510     1 SVIIIFHN------EAlstllrtVHSVINRTppELLKEIILVDDFSDKPElklllEEYYKKYLP-KVKVLRLKKREGLIR 73

                          90
                  ....*....|....*....
gi 490176572  589 ARNAGLQVAQGEILAYLDS 607
Cdd:cd02510    74 ARIAGARAATGDVLVFLDS 92
GT_2_like_b cd04185
Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse ...
 776-984 5.11e-09

Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.


Pssm-ID: 133028 [Multi-domain]  Cd Length: 202  Bit Score: 57.26  E-value: 5.11e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  776 ECLDALTAKDWKGQlKIIVIDNASDRDVVNYLVDREAAGDIDLIQNKRNY----GFtyavNQGIRRA-HAGAD-ILVLNN 849
Cdd:cd04185    14 ECLDALLAQTRPPD-HIIVIDNASTDGTAEWLTSLGDLDNIVYLRLPENLggagGF----YEGVRRAyELGYDwIWLMDD 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  850 DAVVRKGAIQALQKAcYSLPHAGMTVPRQILPAGtktfqthvpfasedydcdvnisahhrniarvpvfhngknlelsfaP 929
Cdd:cd04185    89 DAIPDPDALEKLLAY-ADKDNPQFLAPLVLDPDG---------------------------------------------S 122

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 490176572  930 FFAVYIQRDLIARIGVLDAEYGRHYrSDRVYCDMARNVGGKkiYYVPDAFVIHKL 984
Cdd:cd04185   123 FVGVLISRRVVEKIGLPDKEFFIWG-DDTEYTLRASKAGPG--IYVPDAVVVHKT 174
Glyco_tranf_GTA_type cd00761
Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a ...
 763-880 1.47e-08

Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.


Pssm-ID: 132997 [Multi-domain]  Cd Length: 156  Bit Score: 54.82  E-value: 1.47e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  763 VIIPNWQSLDEINECLDALTAKDWKgQLKIIVIDNASDRDVVNYLVDREAAGD-IDLIQNKRNYGFTYAVNQGIRRAHaG 841
Cdd:cd00761     1 VIIPAYNEEPYLERCLESLLAQTYP-NFEVIVVDDGSTDGTLEILEEYAKKDPrVIRVINEENQGLAAARNAGLKAAR-G 78

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 490176572  842 ADILVLNNDAVVRKGAIQALQKACYSLPHAGMTVPRQIL 880
Cdd:cd00761    79 EYILFLDADDLLLPDWLERLVAELLADPEADAVGGPGNL 117
Glycos_transf_2 pfam00535
Glycosyl transferase family 2; Diverse family, transferring sugar from UDP-glucose, ...
 763-864 3.10e-08

Glycosyl transferase family 2; Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.


Pssm-ID: 425738 [Multi-domain]  Cd Length: 166  Bit Score: 54.32  E-value: 3.10e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572   763 VIIPNWQSLDEINECLDALTAKDWKGqLKIIVIDNASDRDVVNYLVD-REAAGDIDLIQNKRNYGFTYAVNQGIRraHAG 841
Cdd:pfam00535    2 VIIPTYNEEKYLLETLESLLNQTYPN-FEIIVVDDGSTDGTVEIAEEyAKKDPRVRVIRLPENRGKAGARNAGLR--AAT 78

                           90       100
                   ....*....|....*....|....
gi 490176572   842 AD-ILVLNNDAVVRKGAIQALQKA 864
Cdd:pfam00535   79 GDyIAFLDADDEVPPDWLEKLVEA 102
Glyco_tranf_2_3 pfam13641
Glycosyltransferase like family 2; Members of this family of prokaryotic proteins include ...
 761-982 8.68e-08

Glycosyltransferase like family 2; Members of this family of prokaryotic proteins include putative glucosyltransferase, which are involved in bacterial capsule biosynthesis.


Pssm-ID: 433372 [Multi-domain]  Cd Length: 230  Bit Score: 54.30  E-value: 8.68e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572   761 VAVIIPNWQSLDEINECLDALTAKDWkGQLKIIVIDNASDRDVVNYL---VDREAAGDIDLIQNKRNYGFTYAV---NQG 834
Cdd:pfam13641    4 VSVVVPAFNEDSVLGRVLEAILAQPY-PPVEVVVVVNPSDAETLDVAeeiAARFPDVRLRVIRNARLLGPTGKSrglNHG 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572   835 IRRAhAGADILVLNNDAVVRKGAIQALQKACYSLPHAGMTVPRQILPAGTKTFQTHVPFASEDY-DCDVnisahHRNIAR 913
Cdd:pfam13641   83 FRAV-KSDLVVLHDDDSVLHPGTLKKYVQYFDSPKVGAVGTPVFSLNRSTMLSALGALEFALRHlRMMS-----LRLALG 156

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 490176572   914 VPvFHNGKnlelsfapFFAvyIQRDLIARIGVLDAEYgrHYRSDRVYCDMARNVGGkKIYYVPDAFVIH 982
Cdd:pfam13641  157 VL-PLSGA--------GSA--IRREVLKELGLFDPFF--LLGDDKSLGRRLRRHGW-RVAYAPDAAVRT 211
PTZ00260 PTZ00260
dolichyl-phosphate beta-glucosyltransferase; Provisional
 522-639 9.00e-08

dolichyl-phosphate beta-glucosyltransferase; Provisional


Pssm-ID: 240336 [Multi-domain]  Cd Length: 333  Bit Score: 55.16  E-value: 9.00e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  522 ISVIMPVYNRvaivGEAIASVLAQSYHYF------------ELIVVDDCSTDATESAVQAFHDDRI------RLITLPEN 583
Cdd:PTZ00260   72 LSIVIPAYNE----EDRLPKMLKETIKYLesrsrkdpkfkyEIIIVNDGSKDKTLKVAKDFWRQNInpnidiRLLSLLRN 147

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 490176572  584 KGPSAARNAGLQVAQGEILAYLDSDNTWD---------------DRYLAAIAGAFETLPDADAV-----YSGILLY 639
Cdd:PTZ00260  148 KGKGGAVRIGMLASRGKYILMVDADGATDiddfdkledimlkieQNGLGIVFGSRNHLVDSDVVakrkwYRNILMY 223
GT2_RfbF_like cd02526
RfbF is a putative dTDP-rhamnosyl transferase; Shigella flexneri RfbF protein is a putative ...
 762-905 1.10e-07

RfbF is a putative dTDP-rhamnosyl transferase; Shigella flexneri RfbF protein is a putative dTDP-rhamnosyl transferase. dTDP rhamnosyl transferases of Shigella flexneri add rhamnose sugars to N-acetyl-glucosamine in the O-antigen tetrasaccharide repeat. Lipopolysaccharide O antigens are important virulence determinants for many bacteria. The variations of sugar composition, the sequence of the sugars and the linkages in the O antigen provide structural diversity of the O antigen.


Pssm-ID: 133017 [Multi-domain]  Cd Length: 237  Bit Score: 53.83  E-value: 1.10e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  762 AVII---PNwqsLDEINECLDALTAKDWKgqlkIIVIDNASDRDvvNYLVDREAAGDIDLIQNKRNYGFTYAVNQGIRRA 838
Cdd:cd02526     1 AVVVtynPD---LSKLKELLAALAEQVDK----VVVVDNSSGND--IELRLRLNSEKIELIHLGENLGIAKALNIGIKAA 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  839 HA-GAD-ILVLNNDAVVRKGAIQALqKACYSLPH----AGMTVPR----------QILPAGTKTFQTHVPFASEDYDCDV 902
Cdd:cd02526    72 LEnGADyVLLFDQDSVPPPDMVEKL-LAYKILSDknsnIGAVGPRiidrrtgensPGVRKSGYKLRIQKEGEEGLKEVDF 150


                  ...
gi 490176572  903 NIS 905
Cdd:cd02526   151 LIT 153
DPM1_like cd06442
DPM1_like represents putative enzymes similar to eukaryotic DPM1; Proteins similar to ...
 524-608 1.24e-07

DPM1_like represents putative enzymes similar to eukaryotic DPM1; Proteins similar to eukaryotic DPM1, including enzymes from bacteria and archaea; DPM1 is the catalytic subunit of eukaryotic dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. In higher eukaryotes,the enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. In lower eukaryotes, such as Saccharomyces cerevisiae and Trypanosoma brucei, DPM synthase consists of a single component (Dpm1p and TbDpm1, respectively) that possesses one predicted transmembrane region near the C terminus for anchoring to the ER membrane. In contrast, the Dpm1 homologues of higher eukaryotes, namely fission yeast, fungi, and animals, have no transmembrane region, suggesting the existence of adapter molecules for membrane anchoring. This family also includes bacteria and archaea DPM1_like enzymes. However, the enzyme structure and mechanism of function are not well understood. This protein family belongs to Glycosyltransferase 2 superfamily.


Pssm-ID: 133062 [Multi-domain]  Cd Length: 224  Bit Score: 53.69  E-value: 1.24e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  524 VIMPVYNRVAIVGEAIASVLAQSYHY-FELIVVDDCSTDATESAVQAF--HDDRIRLITLPENKGPSAARNAGLQVAQGE 600
Cdd:cd06442     1 IIIPTYNERENIPELIERLDAALKGIdYEIIVVDDNSPDGTAEIVRELakEYPRVRLIVRPGKRGLGSAYIEGFKAARGD 80


                  ....*...
gi 490176572  601 ILAYLDSD 608
Cdd:cd06442    81 VIVVMDAD 88
GT2_Chondriotin_Pol_N cd06420
N-terminal domain of Chondroitin polymerase functions as a GalNAc transferase; Chondroitin ...
 524-608 1.91e-07

N-terminal domain of Chondroitin polymerase functions as a GalNAc transferase; Chondroitin polymerase is a two domain, bi-functional protein. The N-terminal domain functions as a GalNAc transferase. The bacterial chondroitin polymerase catalyzes elongation of the chondroitin chain by alternatively transferring the GlcUA and GalNAc moiety from UDP-GlcUA and UDP-GalNAc to the non-reducing ends of the chondroitin chain. The enzyme consists of N-terminal and C-terminal domains in which the two active sites catalyze the addition of GalNAc and GlcUA, respectively. Chondroitin chains range from 40 to over 100 repeating units of the disaccharide. Sulfated chondroitins are involved in the regulation of various biological functions such as central nervous system development, wound repair, infection, growth factor signaling, and morphogenesis, in addition to its conventional structural roles. In Caenorhabditis elegans, chondroitin is an essential factor for the worm to undergo cytokinesis and cell division. Chondroitin is synthesized as proteoglycans, sulfated and secreted to the cell surface or extracellular matrix.


Pssm-ID: 133042 [Multi-domain]  Cd Length: 182  Bit Score: 52.19  E-value: 1.91e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  524 VIMPVYNRVAIVGEAIASVLAQSYHYFELIVVDDCSTDATESAVQAF-HDDRIRLITL-PENKG--PSAARNAGLQVAQG 599
Cdd:cd06420     1 LIITTYNRPEALELVLKSVLNQSILPFEVIIADDGSTEETKELIEEFkSQFPIPIKHVwQEDEGfrKAKIRNKAIAAAKG 80


                  ....*....
gi 490176572  600 EILAYLDSD 608
Cdd:cd06420    81 DYLIFIDGD 89
WcaA COG0463
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ...
 761-983 2.31e-07

Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440231 [Multi-domain]  Cd Length: 208  Bit Score: 52.40  E-value: 2.31e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  761 VAVIIPNWQSLDEINECLDALTAKDWKGqLKIIVIDNASDRDVVNyLVDREAAGD--IDLIQNKRNYGFTYAVNQGIrrA 838
Cdd:COG0463     4 VSVVIPTYNEEEYLEEALESLLAQTYPD-FEIIVVDDGSTDGTAE-ILRELAAKDprIRVIRLERNRGKGAARNAGL--A 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  839 HAGAD-ILVLNNDAVVRKGAIQALQKACYSLPhAGMTVPRQILPAGTKTFQThvpFASEDYDCdvnisahHRNIARVPVF 917
Cdd:COG0463    80 AARGDyIAFLDADDQLDPEKLEELVAALEEGP-ADLVYGSRLIREGESDLRR---LGSRLFNL-------VRLLTNLPDS 148

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 490176572  918 HNGKNLelsfapffavyIQRDLIARIGvldaeYGRHYRSDRVYCDMARNvgGKKIYYVPDAFVIHK 983
Cdd:COG0463   149 TSGFRL-----------FRREVLEELG-----FDEGFLEDTELLRALRH--GFRIAEVPVRYRAGE 196
GT2_AmsE_like cd04195
GT2_AmsE_like is involved in exopolysaccharide amylovora biosynthesis; AmsE is a ...
 523-637 2.43e-07

GT2_AmsE_like is involved in exopolysaccharide amylovora biosynthesis; AmsE is a glycosyltransferase involved in exopolysaccharide amylovora biosynthesis in Erwinia amylovora. Amylovara is one of the three exopolysaccharide produced by E. amylovora. Amylovara-deficient mutants are non-pathogenic. It is a subfamily of Glycosyltransferase Family GT2, which includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds.


Pssm-ID: 133038 [Multi-domain]  Cd Length: 201  Bit Score: 52.32  E-value: 2.43e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  523 SVIMPVYNRVAIV--GEAIASVLAQSYHYFELIVVDDCS-TDATESAVQAFHDD-RIRLITLPENKGPSAARNAGLQVAQ 598
Cdd:cd04195     1 SVLMSVYIKEKPEflREALESILKQTLPPDEVVLVKDGPvTQSLNEVLEEFKRKlPLKVVPLEKNRGLGKALNEGLKHCT 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 490176572  599 GEILAYLDSDN-TWDDRYlAAIAGAFETLPDADAVYSGIL 637
Cdd:cd04195    81 YDWVARMDTDDiSLPDRF-EKQLDFIEKNPEIDIVGGGVL 119
GT_2_like_e cd04192
Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse ...
 541-697 3.96e-07

Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.


Pssm-ID: 133035 [Multi-domain]  Cd Length: 229  Bit Score: 52.29  E-value: 3.96e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  541 SVLAQSYHY--FELIVVDDCSTDATESAVQAFHDD---RIRLIT--LPENKGPSAARNAGLQVAQGEILAYLDSDNTWDD 613
Cdd:cd04192    18 SLSALDYPKekFEVILVDDHSTDGTVQILEFAAAKpnfQLKILNnsRVSISGKKNALTTAIKAAKGDWIVTTDADCVVPS 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  614 RYLAAIAGAFETlpDADAVYSGILLYRNRDSS-------PFAVRYGHYHRALLENRNYIDM-NIFSHRRGLMDRMSGFDQ 685
Cdd:cd04192    98 NWLLTFVAFIQK--EQIGLVAGPVIYFKGKSLlakfqrlDWLSLLGLIAGSFGLGKPFMCNgANMAYRKEAFFEVGGFEG 175

                         170
                  ....*....|...
gi 490176572  686 NMK-RYVDYDFIL 697
Cdd:cd04192   176 NDHiASGDDELLL 188
Beta4Glucosyltransferase cd02511
UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of ...
 522-642 5.22e-07

UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; UDP-glucose: lipooligosaccharide (LOS) beta-1-4-glucosyltransferase catalyzes the addition of the first residue, glucose, of the lacto-N-neotetrase structure to HepI of the LOS inner core. LOS is the major constituent of the outer leaflet of the outer membrane of gram-positive bacteria. It consists of a short oligosaccharide chain of variable composition (alpha chain) attached to a branched inner core which is lined in turn to lipid A. Beta 1,4 glucosyltransferase is required to attach the alpha chain to the inner core.


Pssm-ID: 133005 [Multi-domain]  Cd Length: 229  Bit Score: 51.91  E-value: 5.22e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  522 ISVIMPVYNRVAIVGEAIASVLAqsyHYFELIVVDDCSTDATESAVQAFhddRIRLITLPeNKGPSAARNAGLQVAQGE- 600
Cdd:cd02511     2 LSVVIITKNEERNIERCLESVKW---AVDEIIVVDSGSTDRTVEIAKEY---GAKVYQRW-WDGFGAQRNFALELATNDw 74

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 490176572  601 ILaYLDSDNTWDDRYLAAIAGAFETLPDADAVYSGILLYRNR 642
Cdd:cd02511    75 VL-SLDADERLTPELADEILALLATDDYDGYYVPRRNFFLGR 115
BcsA COG1215
Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1, ...
 760-880 5.58e-07

Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility];


Pssm-ID: 440828 [Multi-domain]  Cd Length: 303  Bit Score: 52.44  E-value: 5.58e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  760 PVAVIIPNWQSLDEINECLDALTAKDW-KGQLKIIVIDNASDRDVVNyLVDREAAGD--IDLIQNKRNYGFTYAVNQGIR 836
Cdd:COG1215    30 RVSVIIPAYNEEAVIEETLRSLLAQDYpKEKLEVIVVDDGSTDETAE-IARELAAEYprVRVIERPENGGKAAALNAGLK 108

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 490176572  837 RAHAGAdILVLNNDAVVRKGAIQ----ALQKACYSLPHAGMTVPRQIL 880
Cdd:COG1215   109 AARGDI-VVFLDADTVLDPDWLRrlvaAFADPGVGASGANLAFRREAL 155
PRK13915 PRK13915
putative glucosyl-3-phosphoglycerate synthase; Provisional
 522-632 1.30e-06

putative glucosyl-3-phosphoglycerate synthase; Provisional


Pssm-ID: 237556 [Multi-domain]  Cd Length: 306  Bit Score: 51.46  E-value: 1.30e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  522 ISVIMPVYNRVAIVGEAIASVLAQSYHYF--ELIVVDDCSTDAT-ESAVQA----FHDDRIrLITLPENKGPSAARNAGL 594
Cdd:PRK13915   33 VSVVLPALNEEETVGKVVDSIRPLLMEPLvdELIVIDSGSTDATaERAAAAgarvVSREEI-LPELPPRPGKGEALWRSL 111

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 490176572  595 QVAQGEILAYLDSDNT-WDDRYLAAIAGAFETLPDADAV 632
Cdd:PRK13915  112 AATTGDIVVFVDADLInFDPMFVPGLLGPLLTDPGVHLV 150
beta3GnTL1_like cd06913
Beta 1, 3-N-acetylglucosaminyltransferase is essential for the formation of ...
 524-619 1.47e-06

Beta 1, 3-N-acetylglucosaminyltransferase is essential for the formation of poly-N-acetyllactosamine ; This family includes human Beta3GnTL1 and related eukaryotic proteins. Human Beta3GnTL1 is a putative beta-1,3-N-acetylglucosaminyltransferase. Beta3GnTL1 is expressed at various levels in most of tissues examined. Beta 1, 3-N-acetylglucosaminyltransferase has been found to be essential for the formation of poly-N-acetyllactosamine. Poly-N-acetyllactosamine is a unique carbohydrate composed of N-acetyllactosamine repeats. It is often an important part of cell-type-specific oligosaccharide structures and some functional oligosaccharides. It has been shown that the structure and biosynthesis of poly-N-acetyllactosamine display a dramatic change during development and oncogenesis. Several members of beta-1, 3-N-acetylglucosaminyltransferase have been identified.


Pssm-ID: 133063 [Multi-domain]  Cd Length: 219  Bit Score: 50.15  E-value: 1.47e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  524 VIMPVYNRVAIVGEAIASVLAQSYH-YFELIVVDDCSTDATESAVQAF----HDDRIRLITLPEN----KGPSAARNAGL 594
Cdd:cd06913     1 IILPVHNGEQWLDECLESVLQQDFEgTLELSVFNDASTDKSAEIIEKWrkklEDSGVIVLVGSHNspspKGVGYAKNQAI 80

                          90       100       110
                  ....*....|....*....|....*....|
gi 490176572  595 QVAQGEILAYLDSDNTWD-----DRYLAAI 619
Cdd:cd06913    81 AQSSGRYLCFLDSDDVMMpqrirLQYEAAL 110
GT2_HAS cd06434
Hyaluronan synthases catalyze polymerization of hyaluronan; Hyaluronan synthases (HASs) are ...
 522-651 1.93e-06

Hyaluronan synthases catalyze polymerization of hyaluronan; Hyaluronan synthases (HASs) are bi-functional glycosyltransferases that catalyze polymerization of hyaluronan. HASs transfer both GlcUA and GlcNAc in beta-(1,3) and beta-(1,4) linkages, respectively to the hyaluronan chain using UDP-GlcNAc and UDP-GlcUA as substrates. HA is made as a free glycan, not attached to a protein or lipid. HASs do not need a primer for HA synthesis; they initiate HA biosynthesis de novo with only UDP-GlcNAc, UDP-GlcUA, and Mg2+. Hyaluronan (HA) is a linear heteropolysaccharide composed of (1-3)-linked beta-D-GlcUA-beta-D-GlcNAc disaccharide repeats. It can be found in vertebrates and a few microbes and is typically on the cell surface or in the extracellular space, but is also found inside mammalian cells. Hyaluronan has several physiochemical and biological functions such as space filling, lubrication, and providing a hydrated matrix through which cells can migrate.


Pssm-ID: 133056 [Multi-domain]  Cd Length: 235  Bit Score: 50.33  E-value: 1.93e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  522 ISVIMPVYNRVAIV-GEAIASVLAQSYHyfELIVV-DDCSTDATESAVQAFHDDRIRLITLPE-NKgpsaaRNA---GLQ 595
Cdd:cd06434     2 VTVIIPVYDEDPDVfRECLRSILRQKPL--EIIVVtDGDDEPYLSILSQTVKYGGIFVITVPHpGK-----RRAlaeGIR 74

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 490176572  596 VAQGEILAYLDSDNTWDDRYLAAIAGAFETlPDADAVYSGILLYRNRDSSP---FAVRY 651
Cdd:cd06434    75 HVTTDIVVLLDSDTVWPPNALPEMLKPFED-PKVGGVGTNQRILRPRDSKWsflAAEYL 132
GlcNAc-1-P_transferase cd06436
N-acetyl-glucosamine transferase is involved in the synthesis of Poly-beta-1, ...
 524-624 1.09e-05

N-acetyl-glucosamine transferase is involved in the synthesis of Poly-beta-1,6-N-acetyl-D-glucosamine; N-acetyl-glucosamine transferase is responsible for the synthesis of bacteria Poly-beta-1,6-N-acetyl-D-glucosamine (PGA). Poly-beta-1,6-N-acetyl-D-glucosamine is a homopolymer that serves as an adhesion for the maintenance of biofilm structural stability in diverse eubacteria. N-acetyl-glucosamine transferase is the product of gene pgaC. Genetic analysis indicated that all four genes of the pgaABCD locus were required for the PGA production, pgaC being a glycosyltransferase.


Pssm-ID: 133058 [Multi-domain]  Cd Length: 191  Bit Score: 47.38  E-value: 1.09e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  524 VIMPVYNRVAIVGEAIASVLAQSYHyFELIVVDDCSTDATESAVQAF-HDDRIRLIT--LPE-NKGPSAARNAGLQ---- 595
Cdd:cd06436     1 VLVPCLNEEAVIQRTLASLLRNKPN-FLVLVIDDASDDDTAGIVRLAiTDSRVHLLRrhLPNaRTGKGDALNAAYDqirq 79

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 490176572  596 --VAQG-----EILAYLDSDNTWDDRYLAAIAGAFE 624
Cdd:cd06436    80 ilIEEGadperVIIAVIDADGRLDPNALEAVAPYFS 115
EPS_HpsE NF038302
hormogonium polysaccharide biosynthesis glycosyltransferase HpsE;
551-623 5.98e-05

hormogonium polysaccharide biosynthesis glycosyltransferase HpsE;


Pssm-ID: 439602 [Multi-domain]  Cd Length: 307  Bit Score: 46.33  E-value: 5.98e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  551 ELIVVDDCSTDATESAVQAF---HDDRIRLITLPE-NKGPSAARNAGLQVAQGEILAYLDSDNTWDDRYLAAI------- 619
Cdd:NF038302   35 EIIVVDNNSTDNTAQVVQEYqknWPSPYPLRYCFEpQQGAAFARQRAIQEAKGELIGFLDDDNLPAPNWVAAAyafgqeh 114


                  ....*.
gi 490176572  620 --AGAF 623
Cdd:NF038302  115 pqAGAY 120
CESA_like_2 cd06427
CESA_like_2 is a member of the cellulose synthase superfamily; The cellulose synthase (CESA) ...
 520-659 1.49e-04

CESA_like_2 is a member of the cellulose synthase superfamily; The cellulose synthase (CESA) superfamily includes a wide variety of glycosyltransferase family 2 enzymes that share the common characteristic of catalyzing the elongation of polysaccharide chains. The members include cellulose synthase catalytic subunit, chitin synthase, Glucan Biosynthesis protein and other families of CESA-like proteins. Cellulose synthase catalyzes the polymerization reaction of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues in plants, most algae, some bacteria and fungi, and even some animals. In bacteria, algae and lower eukaryotes, there is a second unrelated type of cellulose synthase (Type II), which produces acylated cellulose, a derivative of cellulose. Chitin synthase catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin, which is a linear homopolymer of beta-(1,4)-linked GlcNAc residues and Glucan Biosynthesis protein catalyzes the elongation of beta-1,2 polyglucose chains of glucan.


Pssm-ID: 133049 [Multi-domain]  Cd Length: 241  Bit Score: 44.55  E-value: 1.49e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  520 PLISVIMPVYNRVAIVGEAIASVLAQSY--HYFELIVVDDCSTDATESAVQAFHDDRIRLITLPENKGPSA---ARNAGL 594
Cdd:cd06427     1 PVYTILVPLYKEAEVLPQLIASLSALDYprSKLDVKLLLEEDDEETIAAARALRLPSIFRVVVVPPSQPRTkpkACNYAL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 490176572  595 QVAQGEILAYLDSDNTWDDRYLAAIAGAFETLPDADAVYSGILLYRNRDS----SPFAVRYGHYHRALL 659
Cdd:cd06427    81 AFARGEYVVIYDAEDAPDPDQLKKAVAAFARLDDKLACVQAPLNYYNAREnwltRMFALEYAAWFDYLL 149
CESA_CaSu_A2 cd06437
Cellulose synthase catalytic subunit A2 (CESA2) is a catalytic subunit or a catalytic subunit ...
 520-664 2.78e-04

Cellulose synthase catalytic subunit A2 (CESA2) is a catalytic subunit or a catalytic subunit substitute of the cellulose synthase complex; Cellulose synthase (CESA) catalyzes the polymerization reaction of cellulose using UDP-glucose as the substrate. Cellulose is an aggregate of unbranched polymers of beta-1,4-linked glucose residues, which is an abundant polysaccharide produced by plants and in varying degrees by several other organisms including algae, bacteria, fungi, and even some animals. Genomes from higher plants harbor multiple CESA genes. There are ten in Arabidopsis. At least three different CESA proteins are required to form a functional complex. In Arabidopsis, CESA1, 3 and 6 and CESA4, 7 and 8, are required for cellulose biosynthesis during primary and secondary cell wall formation. CESA2 is very closely related to CESA6 and is viewed as a prime substitute for CESA6. They functionally compensate each other. The cesa2 and cesa6 double mutant plants were significantly smaller, while the single mutant plants were almost normal.


Pssm-ID: 133059 [Multi-domain]  Cd Length: 232  Bit Score: 43.45  E-value: 2.78e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  520 PLISVIMPVYNRVAIVGEAIASVLAQSY--HYFELIVVDDCSTDATESAVQAFHDDR-----IRLITLPENKGPSA-ARN 591
Cdd:cd06437     1 PMVTVQLPVFNEKYVVERLIEAACALDYpkDRLEIQVLDDSTDETVRLAREIVEEYAaqgvnIKHVRRADRTGYKAgALA 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 490176572  592 AGLQVAQGEILAYLDSDntwddrylaaiagaFetLPDADAVYSGILLYRNRDSSPFAVRYGHyhrallENRNY 664
Cdd:cd06437    81 EGMKVAKGEYVAIFDAD--------------F--VPPPDFLQKTPPYFADPKLGFVQTRWGH------INANY 131
CESA_NdvC_like cd06435
NdvC_like proteins in this family are putative bacterial beta-(1,6)-glucosyltransferase; ...
 523-685 2.90e-04

NdvC_like proteins in this family are putative bacterial beta-(1,6)-glucosyltransferase; NdvC_like proteins in this family are putative bacterial beta-(1,6)-glucosyltransferase. Bradyrhizobium japonicum synthesizes periplasmic cyclic beta-(1,3),beta-(1,6)-D-glucans during growth under hypoosmotic conditions. Two genes (ndvB, ndvC) are involved in the beta-(1, 3), beta-(1,6)-glucan synthesis. The ndvC mutant strain resulted in synthesis of altered cyclic beta-glucans composed almost entirely of beta-(1, 3)-glycosyl linkages. The periplasmic cyclic beta-(1,3),beta-(1,6)-D-glucans function for osmoregulation. The ndvC mutation also affects the ability of the bacteria to establish a successful symbiotic interaction with host plant. Thus, the beta-glucans may function as suppressors of a host defense response.


Pssm-ID: 133057 [Multi-domain]  Cd Length: 236  Bit Score: 43.54  E-value: 2.90e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  523 SVIMPVYNRV-AIVGEAIASVLAQSYHYFELIVVDDCSTD-ATESAVQAF---HDDRIRLITLPENKGPSA-ARNAGLQV 596
Cdd:cd06435     1 SIHVPCYEEPpEMVKETLDSLAALDYPNFEVIVIDNNTKDeALWKPVEAHcaqLGERFRFFHVEPLPGAKAgALNYALER 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  597 A--QGEILAYLDSDNTWDDRYLAAIAGAFETlPDADAVYSGiLLYRNRDSSPFAVR----YGHYHRALLENRNYIDmNIF 670
Cdd:cd06435    81 TapDAEIIAVIDADYQVEPDWLKRLVPIFDD-PRVGFVQAP-QDYRDGEESLFKRMcyaeYKGFFDIGMVSRNERN-AII 157

                         170       180
                  ....*....|....*....|.
gi 490176572  671 SH------RRGLMDRMSGFDQ 685
Cdd:cd06435   158 QHgtmcliRRSALDDVGGWDE 178
PRK10714 PRK10714
undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional
 522-608 4.22e-03

undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional


Pssm-ID: 182669 [Multi-domain]  Cd Length: 325  Bit Score: 40.49  E-value: 4.22e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490176572  522 ISVIMPVYNRVAIVGEAIASVLA---QSYHYFELIVVDDCSTDA-----TESAVQAfhDDRIRLITLPENKGPSAARNAG 593
Cdd:PRK10714    8 VSVVIPVYNEQESLPELIRRTTAaceSLGKEYEILLIDDGSSDNsaemlVEAAQAP--DSHIVAILLNRNYGQHSAIMAG 85

                          90
                  ....*....|....*
gi 490176572  594 LQVAQGEILAYLDSD 608
Cdd:PRK10714   86 FSHVTGDLIITLDAD 100
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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