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Conserved domains on  [gi|490173399|ref|WP_004072036|]
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prepilin-type N-terminal cleavage/methylation domain-containing protein [Desulfobacter postgatei]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PilW COG4966
Type IV pilus assembly protein PilW [Cell motility, Extracellular structures];
4-136 4.19e-23

Type IV pilus assembly protein PilW [Cell motility, Extracellular structures];


:

Pssm-ID: 443992 [Multi-domain]  Cd Length: 158  Bit Score: 91.39  E-value: 4.19e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490173399   4 NNQKGFTLIEMMMALVIGAMITAATYATYSSQQKAYQTQDQVAEMQQNLRAALYLIIEEIQMAGYDPEDSGNFSVTsamP 83
Cdd:COG4966    2 RRQRGFTLVELMVALAIGLIVLAAVLQLFLSSRRSYRTQEALARLQENGRFALDLLSRDLRQAGYFGCASGNGNPN---G 78

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 490173399  84 GRIQFETDKDEDGDSADEDNVNDSKETIDLGLSRTFDANGDGIPDTDSDGDGV 136
Cdd:COG4966   79 GASVDIADDVSVLDVLLDTLGGSGDSTLGASSVTGLGDATDALSLDGVRLLVT 131
PilW super family cl38482
Type IV Pilus-assembly protein W; PilW is a family of putative type IV pilus-assembly proteins. ...
 145-237 1.81e-07

Type IV Pilus-assembly protein W; PilW is a family of putative type IV pilus-assembly proteins. PilW is one of the component proteins of the pilus biogenesis process whereby pilus fibres are assembled in the periplasm, emerge onto the cell surface and are there stabilized, to allow bacterial attachment to host cells. PilW is an outer-membrane protein necessary for both the functionality of fibres and their stabilization.


The actual alignment was detected with superfamily member pfam16074:

Pssm-ID: 435119  Cd Length: 126  Bit Score: 48.47  E-value: 1.81e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490173399  145 QTGGAGGFQDIAENIQAVEFLY-LDSAGINLA----LAPPVDLSA------IRSVQITILAIAERSDPKFINSMTYtTPS 213
Cdd:pfam16074  22 GSGGSVTAQPLVEGVEDMQVLYgVDTDGDGTPdryvTASQVTALAttdwrrVVAVRIALLVRSLQPDASYSDTKTY-TLL 100

                          90       100
                  ....*....|....*....|....*.
gi 490173399  214 GQNWGPYND--NFRRRLLTTTIKCRN 237
Cdd:pfam16074 101 GVTVTPPSDtdGYRRHVFTTTVRLRN 126
 
Name Accession Description Interval E-value
PilW COG4966
Type IV pilus assembly protein PilW [Cell motility, Extracellular structures];
4-136 4.19e-23

Type IV pilus assembly protein PilW [Cell motility, Extracellular structures];


Pssm-ID: 443992 [Multi-domain]  Cd Length: 158  Bit Score: 91.39  E-value: 4.19e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490173399   4 NNQKGFTLIEMMMALVIGAMITAATYATYSSQQKAYQTQDQVAEMQQNLRAALYLIIEEIQMAGYDPEDSGNFSVTsamP 83
Cdd:COG4966    2 RRQRGFTLVELMVALAIGLIVLAAVLQLFLSSRRSYRTQEALARLQENGRFALDLLSRDLRQAGYFGCASGNGNPN---G 78

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 490173399  84 GRIQFETDKDEDGDSADEDNVNDSKETIDLGLSRTFDANGDGIPDTDSDGDGV 136
Cdd:COG4966   79 GASVDIADDVSVLDVLLDTLGGSGDSTLGASSVTGLGDATDALSLDGVRLLVT 131
PRK10557 PRK10557
prepilin peptidase-dependent protein;
5-68 4.04e-09

prepilin peptidase-dependent protein;


Pssm-ID: 236714  Cd Length: 192  Bit Score: 54.60  E-value: 4.04e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 490173399   5 NQKGFTLIEMMMALVIGAMITAATYATYSSQQKAYQTQDQVAEMQQNLRAALYLIIEEIQMAGY 68
Cdd:PRK10557   5 KQRGFSLLEVLLAMAIGSVLLLGAARFLPALQRQILTLTRQLRLEDEIWQRVFTVEKDLRRAGY 68
N_methyl pfam07963
Prokaryotic N-terminal methylation motif; This short motif directs methylation of the ...
 4-29 1.22e-07

Prokaryotic N-terminal methylation motif; This short motif directs methylation of the conserved phenylalanine residue. It is most often found at the N-terminus of pilins and other proteins involved in secretion, see pfam00114, pfam05946, pfam02501 and pfam07596.


Pssm-ID: 429756 [Multi-domain]  Cd Length: 27  Bit Score: 46.60  E-value: 1.22e-07
                          10        20
                  ....*....|....*....|....*.
gi 490173399    4 NNQKGFTLIEMMMALVIGAMITAATY 29
Cdd:pfam07963   2 RKQRGFTLIELLVALAILAILLAAAL 27
PilW pfam16074
Type IV Pilus-assembly protein W; PilW is a family of putative type IV pilus-assembly proteins. ...
 145-237 1.81e-07

Type IV Pilus-assembly protein W; PilW is a family of putative type IV pilus-assembly proteins. PilW is one of the component proteins of the pilus biogenesis process whereby pilus fibres are assembled in the periplasm, emerge onto the cell surface and are there stabilized, to allow bacterial attachment to host cells. PilW is an outer-membrane protein necessary for both the functionality of fibres and their stabilization.


Pssm-ID: 435119  Cd Length: 126  Bit Score: 48.47  E-value: 1.81e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490173399  145 QTGGAGGFQDIAENIQAVEFLY-LDSAGINLA----LAPPVDLSA------IRSVQITILAIAERSDPKFINSMTYtTPS 213
Cdd:pfam16074  22 GSGGSVTAQPLVEGVEDMQVLYgVDTDGDGTPdryvTASQVTALAttdwrrVVAVRIALLVRSLQPDASYSDTKTY-TLL 100

                          90       100
                  ....*....|....*....|....*.
gi 490173399  214 GQNWGPYND--NFRRRLLTTTIKCRN 237
Cdd:pfam16074 101 GVTVTPPSDtdGYRRHVFTTTVRLRN 126
IV_pilin_GFxxxE TIGR02532
prepilin-type N-terminal cleavage/methylation domain; This model describes many but not all ...
 6-29 1.30e-05

prepilin-type N-terminal cleavage/methylation domain; This model describes many but not all examples of the N-terminal region of bacterial proteins that resemble type IV pilins at their N-terminus, with a cleavage site G^FxxxE followed by a hydrophobic stretch. The new N-terminal residue, usually Phe, is methylated. Separate domains of the prepilin peptidase appear responsible for cleavage and methylation. Proteins with this N-terminal region include type IV pilins and other components of pilus biogenesis, competence proteins, and type II secretion proteins. Typically several proteins in a single operon have this N-terminal domain. The N-terminal cleavage and methylation site is described by PROSITE motif PS00409 as [KRHEQSTAG]-G-[FYLIVM]-[ST]-[LT]-[LIVP]-E-[LIVMFWSTAG](14). [Cell envelope, Surface structures, Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274182 [Multi-domain]  Cd Length: 24  Bit Score: 40.75  E-value: 1.30e-05
                          10        20
                  ....*....|....*....|....
gi 490173399    6 QKGFTLIEMMMALVIGAMITAATY 29
Cdd:TIGR02532   1 QRGFTLIELLVVLAILGILALIAL 24
T4P_ComGE NF041013
competence type IV pilus minor pilin ComGE;
4-58 1.04e-03

competence type IV pilus minor pilin ComGE;


Pssm-ID: 468942 [Multi-domain]  Cd Length: 83  Bit Score: 37.18  E-value: 1.04e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 490173399   4 NNQKGFTLIEMMMALVIGAMITAA--TYATYSSQQKAYQTQDQvaEMQQNLRAALYL 58
Cdd:NF041013   1 KKNKGFILLESLVALALLALIVSLllPSLTQIQKEREEIKQKE--EALQVLYEALQT 55
pilin_ComGC NF040999
competence type IV pilus major pilin ComGC; ComGC, encoded in the comG operon, is the major ...
 6-68 1.16e-03

competence type IV pilus major pilin ComGC; ComGC, encoded in the comG operon, is the major pilin of a type IV pilus involved in natural transformation of monoderm bacteria (those lacking an outer membrane) such as Bacillus subtilis and Streptococcus pneumoniae. In the seed alignment, Bacillus proteins have a pair of Cys residues likely to form a disulfide bond while Streptococcus proteins lack Cys residues.


Pssm-ID: 468929  Cd Length: 84  Bit Score: 36.72  E-value: 1.16e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 490173399   6 QKGFTLIEMMMALVIGAMITAATYATYSSQQ------------KAYQTQDQVAEMQQNLRAALyliiEEIQMAGY 68
Cdd:NF040999   1 VKGFTLIEMLIVLLIISVLLLLFVPNLSKQKesvqekgceavvKVVESQVELYELDHNKKPSL----SELVSEGY 71
ComGD NF040982
competence type IV pilus minor pilin ComGD;
6-123 2.42e-03

competence type IV pilus minor pilin ComGD;


Pssm-ID: 468912 [Multi-domain]  Cd Length: 140  Bit Score: 37.22  E-value: 2.42e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490173399   6 QKGFTLIEMMMALVIGAMITAATYATYSSQQKAYQTQDQ-VAEMQQNLRAA-LYLIIEEIQMagydpedsgnfsvtsamp 83
Cdd:NF040982   1 IKGFTLLESLLVLLIVSSLLLLTLSLSIPQTYEQVEEKLfFEQFENDLLYAqQYAIASQQST------------------ 62

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 490173399  84 gRIQFETDKD-----EDGDSADEDNVNDSKETIDLGL--SRTFDANG 123
Cdd:NF040982  63 -TITFSPDEIqyqfqEGGNTSNRPYPLKIPISITVTKpnTITFNKNG 108
 
Name Accession Description Interval E-value
PilW COG4966
Type IV pilus assembly protein PilW [Cell motility, Extracellular structures];
4-136 4.19e-23

Type IV pilus assembly protein PilW [Cell motility, Extracellular structures];


Pssm-ID: 443992 [Multi-domain]  Cd Length: 158  Bit Score: 91.39  E-value: 4.19e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490173399   4 NNQKGFTLIEMMMALVIGAMITAATYATYSSQQKAYQTQDQVAEMQQNLRAALYLIIEEIQMAGYDPEDSGNFSVTsamP 83
Cdd:COG4966    2 RRQRGFTLVELMVALAIGLIVLAAVLQLFLSSRRSYRTQEALARLQENGRFALDLLSRDLRQAGYFGCASGNGNPN---G 78

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 490173399  84 GRIQFETDKDEDGDSADEDNVNDSKETIDLGLSRTFDANGDGIPDTDSDGDGV 136
Cdd:COG4966   79 GASVDIADDVSVLDVLLDTLGGSGDSTLGASSVTGLGDATDALSLDGVRLLVT 131
PulJ COG4795
Type II secretory pathway, PulJ/GspJ component [Intracellular trafficking, secretion, and ...
 1-76 3.18e-16

Type II secretory pathway, PulJ/GspJ component [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443823 [Multi-domain]  Cd Length: 118  Bit Score: 72.36  E-value: 3.18e-16
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 490173399   1 MAVNNQKGFTLIEMMMALVIGAMITAATYATYSSQQKAYQTQDQVAEMQQNLRAALYLIIEEIQMAGYDPEDSGNF 76
Cdd:COG4795    3 RARRRQRGFTLLELLVALAIFALLLLAAYRGLDSVLRSRERLEQQAERLQELQRALALLERDLRQAGPRPDEGGDP 78
PRK10557 PRK10557
prepilin peptidase-dependent protein;
5-68 4.04e-09

prepilin peptidase-dependent protein;


Pssm-ID: 236714  Cd Length: 192  Bit Score: 54.60  E-value: 4.04e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 490173399   5 NQKGFTLIEMMMALVIGAMITAATYATYSSQQKAYQTQDQVAEMQQNLRAALYLIIEEIQMAGY 68
Cdd:PRK10557   5 KQRGFSLLEVLLAMAIGSVLLLGAARFLPALQRQILTLTRQLRLEDEIWQRVFTVEKDLRRAGY 68
PulG COG2165
Type II secretory pathway, pseudopilin PulG [Cell motility, Intracellular trafficking, ...
 4-56 1.03e-07

Type II secretory pathway, pseudopilin PulG [Cell motility, Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 441768 [Multi-domain]  Cd Length: 99  Bit Score: 48.76  E-value: 1.03e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 490173399   4 NNQKGFTLIEMMMALVIGAMITAATYATYSSQQKAYQTQDQVAEMQQnLRAAL 56
Cdd:COG2165    8 RRQRGFTLIELLVVIAIIGILAALALPALQGARERARRAELRSNLRQ-IQQAL 59
FimT COG4970
Type IV pilus assembly protein FimT [Cell motility, Extracellular structures];
5-55 1.13e-07

Type IV pilus assembly protein FimT [Cell motility, Extracellular structures];


Pssm-ID: 443996 [Multi-domain]  Cd Length: 73  Bit Score: 47.92  E-value: 1.13e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 490173399   5 NQKGFTLIEMMMALVIGAMITAATYATYSSQQKAYQTQDQVAEMQQNLRAA 55
Cdd:COG4970    7 RQRGFTLIELLVVLAILAILAAIAVPSFSSLIARQRLRAAANELAAALRLA 57
N_methyl pfam07963
Prokaryotic N-terminal methylation motif; This short motif directs methylation of the ...
 4-29 1.22e-07

Prokaryotic N-terminal methylation motif; This short motif directs methylation of the conserved phenylalanine residue. It is most often found at the N-terminus of pilins and other proteins involved in secretion, see pfam00114, pfam05946, pfam02501 and pfam07596.


Pssm-ID: 429756 [Multi-domain]  Cd Length: 27  Bit Score: 46.60  E-value: 1.22e-07
                          10        20
                  ....*....|....*....|....*.
gi 490173399    4 NNQKGFTLIEMMMALVIGAMITAATY 29
Cdd:pfam07963   2 RKQRGFTLIELLVALAILAILLAAAL 27
PilW pfam16074
Type IV Pilus-assembly protein W; PilW is a family of putative type IV pilus-assembly proteins. ...
 145-237 1.81e-07

Type IV Pilus-assembly protein W; PilW is a family of putative type IV pilus-assembly proteins. PilW is one of the component proteins of the pilus biogenesis process whereby pilus fibres are assembled in the periplasm, emerge onto the cell surface and are there stabilized, to allow bacterial attachment to host cells. PilW is an outer-membrane protein necessary for both the functionality of fibres and their stabilization.


Pssm-ID: 435119  Cd Length: 126  Bit Score: 48.47  E-value: 1.81e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490173399  145 QTGGAGGFQDIAENIQAVEFLY-LDSAGINLA----LAPPVDLSA------IRSVQITILAIAERSDPKFINSMTYtTPS 213
Cdd:pfam16074  22 GSGGSVTAQPLVEGVEDMQVLYgVDTDGDGTPdryvTASQVTALAttdwrrVVAVRIALLVRSLQPDASYSDTKTY-TLL 100

                          90       100
                  ....*....|....*....|....*.
gi 490173399  214 GQNWGPYND--NFRRRLLTTTIKCRN 237
Cdd:pfam16074 101 GVTVTPPSDtdGYRRHVFTTTVRLRN 126
PilE COG4968
Type IV pilus assembly protein PilE [Cell motility, Extracellular structures];
1-55 1.82e-06

Type IV pilus assembly protein PilE [Cell motility, Extracellular structures];


Pssm-ID: 443994 [Multi-domain]  Cd Length: 124  Bit Score: 45.84  E-value: 1.82e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 490173399   1 MAVNNQKGFTLIEMMMALVIGAMITAATYATYSSqqkaYQTQDQVAEMQQNLRAA 55
Cdd:COG4968    4 RMRRRQRGFTLIELMIVVAIIGILAAIAIPSYQD----YVERARRAEAKAALLEL 54
IV_pilin_GFxxxE TIGR02532
prepilin-type N-terminal cleavage/methylation domain; This model describes many but not all ...
 6-29 1.30e-05

prepilin-type N-terminal cleavage/methylation domain; This model describes many but not all examples of the N-terminal region of bacterial proteins that resemble type IV pilins at their N-terminus, with a cleavage site G^FxxxE followed by a hydrophobic stretch. The new N-terminal residue, usually Phe, is methylated. Separate domains of the prepilin peptidase appear responsible for cleavage and methylation. Proteins with this N-terminal region include type IV pilins and other components of pilus biogenesis, competence proteins, and type II secretion proteins. Typically several proteins in a single operon have this N-terminal domain. The N-terminal cleavage and methylation site is described by PROSITE motif PS00409 as [KRHEQSTAG]-G-[FYLIVM]-[ST]-[LT]-[LIVP]-E-[LIVMFWSTAG](14). [Cell envelope, Surface structures, Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274182 [Multi-domain]  Cd Length: 24  Bit Score: 40.75  E-value: 1.30e-05
                          10        20
                  ....*....|....*....|....
gi 490173399    6 QKGFTLIEMMMALVIGAMITAATY 29
Cdd:TIGR02532   1 QRGFTLIELLVVLAILGILALIAL 24
PilV COG4967
Type IV pilus assembly protein PilV [Cell motility, Extracellular structures];
1-55 2.81e-05

Type IV pilus assembly protein PilV [Cell motility, Extracellular structures];


Pssm-ID: 443993 [Multi-domain]  Cd Length: 86  Bit Score: 41.51  E-value: 2.81e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 490173399   1 MAVNNQKGFTLIEMMMALVI--------GAMITAATYATYSSQQK---AYQTQDQVAEMQQNLRAA 55
Cdd:COG4967    5 RRRRRQRGFTLIEVLVALVIlsigllglAGLQAASLRSSQDARQRtqaALLAQDLLERLRANPAAA 70
PilA COG4969
Type IV pilus assembly protein, major pilin PilA [Cell motility, Extracellular structures];
4-85 7.65e-05

Type IV pilus assembly protein, major pilin PilA [Cell motility, Extracellular structures];


Pssm-ID: 443995 [Multi-domain]  Cd Length: 134  Bit Score: 41.23  E-value: 7.65e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490173399   4 NNQKGFTLIEMMMALVIGAMITAATYATYSSqqkaYQTQDQVAEMQQNLRAALYLIIEEIQMAGYDPE-DSGNFSVTSAM 82
Cdd:COG4969    3 KKQKGFTLIELMIVVAIIGILAAIAIPAYQD----YVARARVSEALALASPLKTAVEECALENGSLPNcNAGDNGLPATI 78


                 ...
gi 490173399  83 PGR 85
Cdd:COG4969   79 ATK 81
PRK10506 PRK10506
prepilin peptidase-dependent protein;
4-56 1.16e-04

prepilin peptidase-dependent protein;


Pssm-ID: 236704 [Multi-domain]  Cd Length: 162  Bit Score: 41.13  E-value: 1.16e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 490173399   4 NNQKGFTLIEMMMALVIGAMITAAtyATYSSQQkaYQTQDQVAEMQQNLRAAL 56
Cdd:PRK10506   6 KKQRGYTLIELLVVMTIVSILSAW--GLYGWQR--WQQRQRLWQTAQQLLDFL 54
typeII_sec_gspH TIGR01708
type II secretion system protein H; This model represents GspH, protein H of the main terminal ...
 6-74 1.79e-04

type II secretion system protein H; This model represents GspH, protein H of the main terminal branch of the general secretion pathway, also called type II secretion. It transports folded proteins across the bacterial outer membrane and is widely distributed in Gram-negative pathogens. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]


Pssm-ID: 130769 [Multi-domain]  Cd Length: 143  Bit Score: 40.63  E-value: 1.79e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 490173399    6 QKGFTLIEMMMALVIGAMITAATYATYSSQQKAYQTQDQVAEMQQNLRAALYLIIEEIQMAGYDPEDSG 74
Cdd:TIGR01708   3 QSGFTLIELLVVLAIMGLVAAAAALSLVSHYGTKSLDQVAGRLAARLRLAQTSARATGRPVLLRLGSRG 71
ComGC COG4537
Competence protein ComGC [Mobilome: prophages, transposons];
4-49 2.51e-04

Competence protein ComGC [Mobilome: prophages, transposons];


Pssm-ID: 443603 [Multi-domain]  Cd Length: 108  Bit Score: 39.52  E-value: 2.51e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 490173399   4 NNQKGFTLIEMMMALVIGAMITAATYATYSSQQKAYQTQDQVAEMQ 49
Cdd:COG4537    9 KKEKGFTLIEMLIVLLIISILLLIAVPNLTKQRETAQEKGCEANIK 54
ComGF COG4940
Competence protein ComGF [Mobilome: prophages, transposons];
2-94 8.61e-04

Competence protein ComGF [Mobilome: prophages, transposons];


Pssm-ID: 443967 [Multi-domain]  Cd Length: 153  Bit Score: 38.84  E-value: 8.61e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490173399   2 AVNNQKGFTLIEMMMALVIGAMITA--ATYATYSSQQKAYQTQDQvaemQQNLRAALYLIIEEIqmagydpEDSGNFSVT 79
Cdd:COG4940   11 ASINRKGFTLLEKLAALMIIAYILAvlELLLKLLLKLNQSLDAGE----QIEWELFIEQLIFEL-------LEAKLIEVR 79

                         90
                 ....*....|....*
gi 490173399  80 SAmpgRIQFETDKDE 94
Cdd:COG4940   80 SN---RLVLTDIKPP 91
T4P_ComGE NF041013
competence type IV pilus minor pilin ComGE;
4-58 1.04e-03

competence type IV pilus minor pilin ComGE;


Pssm-ID: 468942 [Multi-domain]  Cd Length: 83  Bit Score: 37.18  E-value: 1.04e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 490173399   4 NNQKGFTLIEMMMALVIGAMITAA--TYATYSSQQKAYQTQDQvaEMQQNLRAALYL 58
Cdd:NF041013   1 KKNKGFILLESLVALALLALIVSLllPSLTQIQKEREEIKQKE--EALQVLYEALQT 55
pilin_ComGC NF040999
competence type IV pilus major pilin ComGC; ComGC, encoded in the comG operon, is the major ...
 6-68 1.16e-03

competence type IV pilus major pilin ComGC; ComGC, encoded in the comG operon, is the major pilin of a type IV pilus involved in natural transformation of monoderm bacteria (those lacking an outer membrane) such as Bacillus subtilis and Streptococcus pneumoniae. In the seed alignment, Bacillus proteins have a pair of Cys residues likely to form a disulfide bond while Streptococcus proteins lack Cys residues.


Pssm-ID: 468929  Cd Length: 84  Bit Score: 36.72  E-value: 1.16e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 490173399   6 QKGFTLIEMMMALVIGAMITAATYATYSSQQ------------KAYQTQDQVAEMQQNLRAALyliiEEIQMAGY 68
Cdd:NF040999   1 VKGFTLIEMLIVLLIISVLLLLFVPNLSKQKesvqekgceavvKVVESQVELYELDHNKKPSL----SELVSEGY 71
ComGD NF040982
competence type IV pilus minor pilin ComGD;
6-123 2.42e-03

competence type IV pilus minor pilin ComGD;


Pssm-ID: 468912 [Multi-domain]  Cd Length: 140  Bit Score: 37.22  E-value: 2.42e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490173399   6 QKGFTLIEMMMALVIGAMITAATYATYSSQQKAYQTQDQ-VAEMQQNLRAA-LYLIIEEIQMagydpedsgnfsvtsamp 83
Cdd:NF040982   1 IKGFTLLESLLVLLIVSSLLLLTLSLSIPQTYEQVEEKLfFEQFENDLLYAqQYAIASQQST------------------ 62

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 490173399  84 gRIQFETDKD-----EDGDSADEDNVNDSKETIDLGL--SRTFDANG 123
Cdd:NF040982  63 -TITFSPDEIqyqfqEGGNTSNRPYPLKIPISITVTKpnTITFNKNG 108
gspJ TIGR01711
type II secretion system protein J; This model represents GspJ, one of two proteins highly ...
 8-66 5.22e-03

type II secretion system protein J; This model represents GspJ, one of two proteins highly conserved at their N-termini and described by pfam02501 but easily separable phylogenetically. The other is GspI. Both GspI and GspJ are proteins of the type II secretion pathway, or main terminal branch of the general secretion pathway. This pathway carries proteins across the outer membrane. Note that proteins of type II secretion are cryptic in E. coli K-12 - present but not yet demonstrated to act on any target.


Pssm-ID: 130772 [Multi-domain]  Cd Length: 192  Bit Score: 36.82  E-value: 5.22e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 490173399    8 GFTLIEMMMALVIGAMITAATYATYSSQQKAYQ-TQDQVAEMQQNLRAALYLIIEEIQMA 66
Cdd:TIGR01711   2 GFTLLELLVAIAIFASLSLGAYQVLDSVMQSDEaTRVQEARLRELQRAMGAMERDLTQMV 61
PRK10574 PRK10574
putative major pilin subunit; Provisional
 4-41 9.82e-03

putative major pilin subunit; Provisional


Pssm-ID: 236718 [Multi-domain]  Cd Length: 146  Bit Score: 35.39  E-value: 9.82e-03
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 490173399   4 NNQKGFTLIEMMMALVIGAMITAATYATYSSQ-QKAYQT 41
Cdd:PRK10574   2 DKQRGFTLIELMVVIAIIAILSAIGIPAYQNYlQKAALT 40
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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