NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|490023884|ref|WP_003926361|]
View 

(7aS)-7a-methyl-1,5-dioxo-2,3,5,6,7,7a-hexahydro-1H-indene-carboxyl-CoA hydrolase [Mycolicibacterium thermoresistibile]

Protein Classification

enoyl-CoA hydratase/isomerase family protein( domain architecture ID 10792993)

enoyl-CoA hydratase/isomerase family protein similar to Mycobacterium tuberculosis enoyl-CoA hydratase EchA20

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
PRK07938 PRK07938
enoyl-CoA hydratase family protein;
1-249 7.41e-174

enoyl-CoA hydratase family protein;


:

Pssm-ID: 181174  Cd Length: 249  Bit Score: 478.31  E-value: 7.41e-174
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   1 MPITTTSPEPGIVSVTVDYPPVNAIPSRGWFELADAITAAGRDQQTHVVILRAEGRGFNAGVDIKEMQNTEGFTALIDAN 80
Cdd:PRK07938   1 MPITSTTPEPGIAEVTVDYPPVNALPSAGWFALADAITAAGADPDTRVVVLRAEGRGFNAGVDIKELQATPGFTALIDAN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  81 RGCYEAFRAVYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERGALGAATHLSRLVPQHMMRRLFFTAA 160
Cdd:PRK07938  81 RGCFAAFRAVYECAVPVIAAVHGFCLGGGIGLVGNADVIVASDDATFGLPEVDRGALGAATHLQRLVPQHLMRALFFTAA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884 161 TVDAHTLHHFGSVHEVVPRAELDEAALRVARDIAAKDTRVIRAAKEALNFIDVQRVNSSYRMEQGFTFELNLAGVADEHR 240
Cdd:PRK07938 161 TITAAELHHFGSVEEVVPRDQLDEAALEVARKIAAKDTRVIRAAKEALNGIDPQDVERSYRWEQGFTFELNLAGVSDEHR 240


                 ....*....
gi 490023884 241 DAFAGTNKG 249
Cdd:PRK07938 241 DAFVEKRKA 249
 
Name Accession Description Interval E-value
PRK07938 PRK07938
enoyl-CoA hydratase family protein;
1-249 7.41e-174

enoyl-CoA hydratase family protein;


Pssm-ID: 181174  Cd Length: 249  Bit Score: 478.31  E-value: 7.41e-174
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   1 MPITTTSPEPGIVSVTVDYPPVNAIPSRGWFELADAITAAGRDQQTHVVILRAEGRGFNAGVDIKEMQNTEGFTALIDAN 80
Cdd:PRK07938   1 MPITSTTPEPGIAEVTVDYPPVNALPSAGWFALADAITAAGADPDTRVVVLRAEGRGFNAGVDIKELQATPGFTALIDAN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  81 RGCYEAFRAVYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERGALGAATHLSRLVPQHMMRRLFFTAA 160
Cdd:PRK07938  81 RGCFAAFRAVYECAVPVIAAVHGFCLGGGIGLVGNADVIVASDDATFGLPEVDRGALGAATHLQRLVPQHLMRALFFTAA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884 161 TVDAHTLHHFGSVHEVVPRAELDEAALRVARDIAAKDTRVIRAAKEALNFIDVQRVNSSYRMEQGFTFELNLAGVADEHR 240
Cdd:PRK07938 161 TITAAELHHFGSVEEVVPRDQLDEAALEVARKIAAKDTRVIRAAKEALNGIDPQDVERSYRWEQGFTFELNLAGVSDEHR 240


                 ....*....
gi 490023884 241 DAFAGTNKG 249
Cdd:PRK07938 241 DAFVEKRKA 249
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
 9-244 9.96e-63

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 196.54  E-value: 9.96e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   9 EPGIVSVTVDYP-PVNAIPSRGWFELADAITAAGRDQQTHVVILRAEGRGFNAGVDIKEMQNTEGFTALIDANRGCYEAF 87
Cdd:COG1024    6 EGGVATITLNRPeKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAAAADPEEARAFARGLQRLF 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  88 RAVYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERG---ALGAATHLSRLVPQHMMRRLFFTAATVDA 164
Cdd:COG1024   86 RALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGlipGGGGTQRLPRLVGLARAKELLLTGRRIDA 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884 165 HTLHHFGSVHEVVPRAELDEAALRVARDIAAKDTRVIRAAKEALNFIDVQRVNSSYRMEQGFTFELNLAGVADEHRDAFA 244
Cdd:COG1024  166 EEALELGLVNRVVPDDELLAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAREGIAAFL 245
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
 9-193 3.95e-52

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 167.74  E-value: 3.95e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   9 EPGIVSVTVDYPP-VNAIPSRGWFELADAITAAGRDQQTHVVILRAEGRGFNAGVDIKEMQNTEGFTALIDAN-RGCYEA 86
Cdd:cd06558    6 DGGVATITLNRPEkRNALSLEMLDELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAALSDAGEEARAFiRELQEL 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  87 FRAVYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERGAL---GAATHLSRLVPQHMMRRLFFTAATVD 163
Cdd:cd06558   86 LRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVpggGGTQRLPRLVGPARARELLLTGRRIS 165

                        170       180       190
                 ....*....|....*....|....*....|
gi 490023884 164 AHTLHHFGSVHEVVPRAELDEAALRVARDI 193
Cdd:cd06558  166 AEEALELGLVDEVVPDEELLAAALELARRL 195
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 11-234 1.40e-28

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 108.60  E-value: 1.40e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   11 GIVSVTVDYP-PVNAIPSRGWFELADAITAAGRDQQTHVVILRAEGRGFNAGVDIKEMQN-TEGFTALIDANrgCYEAFR 88
Cdd:pfam00378   5 GVAVITLNRPeAVNALSAELITELIQALEKLRTDPSVRAVVLTGGDKAFCAGADLKEMYGeGPAHQALYREN--VLDLWT 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   89 AVYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERG---ALGAATHLSRLVPQHMMRRLFFTAATVDAH 165
Cdd:pfam00378  83 LLYTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGiipGAGGTDRLPRIIGHSKAMEMLLLGRRISAQ 162

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 490023884  166 TLHHFGSVHEVVPRAELDEAALRVARDIAAKDTRVIRAAKEALNfidvqrVNSSYRMEQGFTFELNLAG 234
Cdd:pfam00378 163 EALKWGLVDKVVPEDQLLDEARELAEKLAEKSPAALAQLKKALN------AKLEDALPTQLEAEARLFY 225
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
 11-202 1.03e-10

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 61.39  E-value: 1.03e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   11 GIVSVTVDYP--PVNAIPSrgwfELADAITAAGRDQQTH-----VVILRAEGRGFNAGVDIKEMQNTEGFTALIDANRGC 83
Cdd:TIGR02441  22 DVAVVKIDSPnsKVNTLSK----ELFAEFKEVMNELWTNeaiksAVLISGKPGSFVAGADIQMIAACKTAQEVTQLSQEG 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   84 YEAFRAVYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAK--FGLPEVERGAL---GAATHLSRLVPQHMMRRLFFT 158
Cdd:TIGR02441  98 QEMFERIEKSQKPIVAAISGSCLGGGLELALACHYRIATKDRKtlLGLPEVMLGLLpgaGGTQRLPKLTGVPAALDMMLT 177

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 490023884  159 AATVDAHTLHHFGSVHEVV--------PRAE-----LDEAALRVARDIAAKDTRVIR 202
Cdd:TIGR02441 178 GKKIRADRAKKMGIVDQLVdplgpglkPAEEntieyLEEVAVKFAQGLANGKLSINR 234
 
Name Accession Description Interval E-value
PRK07938 PRK07938
enoyl-CoA hydratase family protein;
1-249 7.41e-174

enoyl-CoA hydratase family protein;


Pssm-ID: 181174  Cd Length: 249  Bit Score: 478.31  E-value: 7.41e-174
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   1 MPITTTSPEPGIVSVTVDYPPVNAIPSRGWFELADAITAAGRDQQTHVVILRAEGRGFNAGVDIKEMQNTEGFTALIDAN 80
Cdd:PRK07938   1 MPITSTTPEPGIAEVTVDYPPVNALPSAGWFALADAITAAGADPDTRVVVLRAEGRGFNAGVDIKELQATPGFTALIDAN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  81 RGCYEAFRAVYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERGALGAATHLSRLVPQHMMRRLFFTAA 160
Cdd:PRK07938  81 RGCFAAFRAVYECAVPVIAAVHGFCLGGGIGLVGNADVIVASDDATFGLPEVDRGALGAATHLQRLVPQHLMRALFFTAA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884 161 TVDAHTLHHFGSVHEVVPRAELDEAALRVARDIAAKDTRVIRAAKEALNFIDVQRVNSSYRMEQGFTFELNLAGVADEHR 240
Cdd:PRK07938 161 TITAAELHHFGSVEEVVPRDQLDEAALEVARKIAAKDTRVIRAAKEALNGIDPQDVERSYRWEQGFTFELNLAGVSDEHR 240


                 ....*....
gi 490023884 241 DAFAGTNKG 249
Cdd:PRK07938 241 DAFVEKRKA 249
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
 9-244 9.96e-63

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 196.54  E-value: 9.96e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   9 EPGIVSVTVDYP-PVNAIPSRGWFELADAITAAGRDQQTHVVILRAEGRGFNAGVDIKEMQNTEGFTALIDANRGCYEAF 87
Cdd:COG1024    6 EGGVATITLNRPeKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAAAADPEEARAFARGLQRLF 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  88 RAVYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERG---ALGAATHLSRLVPQHMMRRLFFTAATVDA 164
Cdd:COG1024   86 RALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGlipGGGGTQRLPRLVGLARAKELLLTGRRIDA 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884 165 HTLHHFGSVHEVVPRAELDEAALRVARDIAAKDTRVIRAAKEALNFIDVQRVNSSYRMEQGFTFELNLAGVADEHRDAFA 244
Cdd:COG1024  166 EEALELGLVNRVVPDDELLAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAREGIAAFL 245
PRK06495 PRK06495
enoyl-CoA hydratase/isomerase family protein;
1-243 1.10e-53

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 168580 [Multi-domain]  Cd Length: 257  Bit Score: 174.11  E-value: 1.10e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   1 MPITTTSPEPGIVSVTVDYPPVNAIPSRGWFELADAITAAGRDQQTHVVILRAEGRGFNAGVDIKEMQNTE-GFTALIDA 79
Cdd:PRK06495   3 MSQLKLEVSDHVAVVTLDNPPVNALSRELRDELIAVFDEISERPDVRVVVLTGAGKVFCAGADLKGRPDVIkGPGDLRAH 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  80 NRGCYEAFRAVYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERGALGAATHLSRLVPQHMMRRLFFTA 159
Cdd:PRK06495  83 NRRTRECFHAIRECAKPVIAAVNGPALGAGLGLVASCDIIVASENAVFGLPEIDVGLAGGGKHAMRLFGHSLTRRMMLTG 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884 160 ATVDAHTLHHFGSVHEVVPRAELDEAALRVARDIAAKDTRVIRAAKEALNFIDVQRVNSSYRMEQGFTFELNLAGVADEH 239
Cdd:PRK06495 163 YRVPAAELYRRGVIEACLPPEELMPEAMEIAREIASKSPLATRLAKDALNTIENMSLRDGYRYEQDITAKLAKTEDAKEA 242


                 ....
gi 490023884 240 RDAF 243
Cdd:PRK06495 243 QRAF 246
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
 9-193 3.95e-52

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 167.74  E-value: 3.95e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   9 EPGIVSVTVDYPP-VNAIPSRGWFELADAITAAGRDQQTHVVILRAEGRGFNAGVDIKEMQNTEGFTALIDAN-RGCYEA 86
Cdd:cd06558    6 DGGVATITLNRPEkRNALSLEMLDELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAALSDAGEEARAFiRELQEL 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  87 FRAVYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERGAL---GAATHLSRLVPQHMMRRLFFTAATVD 163
Cdd:cd06558   86 LRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVpggGGTQRLPRLVGPARARELLLTGRRIS 165

                        170       180       190
                 ....*....|....*....|....*....|
gi 490023884 164 AHTLHHFGSVHEVVPRAELDEAALRVARDI 193
Cdd:cd06558  166 AEEALELGLVDEVVPDEELLAAALELARRL 195
PRK09674 PRK09674
enoyl-CoA hydratase-isomerase; Provisional
 1-243 2.89e-35

enoyl-CoA hydratase-isomerase; Provisional


Pssm-ID: 182026 [Multi-domain]  Cd Length: 255  Bit Score: 126.42  E-value: 2.89e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   1 MPITTTSPEPGIVSVTVDYPPV-NAIPSRGWFELADAITAAGRDQQTHVVILRAEGRGFNAGVDIKEMQNTEGFTALIDA 79
Cdd:PRK09674   1 MSELLVSRQQRVLLLTLNRPEArNALNNALLTQLVNELEAAATDTSIGVCVITGNARFFAAGADLNEMAEKDLAATLNDP 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  80 NRGCYEAFRAVyecAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERGAL---GAATHLSRLVPQHMMRRLF 156
Cdd:PRK09674  81 RPQLWQRLQAF---NKPLIAAVNGYALGAGCELALLCDIVIAGENARFGLPEITLGIMpgaGGTQRLIRSVGKSLASQMV 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884 157 FTAATVDAHTLHHFGSVHEVVPRAELDEAALRVARDIAAKDTRVIRAAKEALNFIDVQRVNSSYRME-QGFTFelnLAGV 235
Cdd:PRK09674 158 LTGESITAQQAQQAGLVSEVFPPELTLERALQLASKIARHSPLALRAAKQALRQSQEVDLQAGLAQErQLFTL---LAAT 234

                        250
                 ....*....|
gi 490023884 236 ADEHR--DAF 243
Cdd:PRK09674 235 EDRHEgiSAF 244
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
 9-208 3.89e-34

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 123.50  E-value: 3.89e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   9 EPGIVSVTVDYPPV-NAIPSRGWFELADAITAAGRDQQTHVVILRAEGRGFNAGVDIKEMQNTEGFT---ALIDANRgCY 84
Cdd:PRK05995  11 RGQVATVTLNRPDVrNAFNETVIAELTAAFRALDADDSVRAVVLAGAGKAFCAGADLNWMKKMAGYSddeNRADARR-LA 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  85 EAFRAVYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERGALGA--ATHLSRLVPQHMMRRLFFTAATV 162
Cdd:PRK05995  90 DMLRAIYRCPKPVIARVHGDAYAGGMGLVAACDIAVAADHAVFCLSEVRLGLIPAtiSPYVIRAMGERAARRYFLTAERF 169

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 490023884 163 DAHTLHHFGSVHEVVPRAELDEAALRVARDIAAKDTRVIRAAKEAL 208
Cdd:PRK05995 170 DAAEALRLGLVHEVVPAEALDAKVDELLAALVANSPQAVRAGKRLV 215
PRK06190 PRK06190
enoyl-CoA hydratase; Provisional
 1-252 4.37e-33

enoyl-CoA hydratase; Provisional


Pssm-ID: 235733  Cd Length: 258  Bit Score: 120.85  E-value: 4.37e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   1 MPITTTSPEPGIVSVTVDYPPV-NAIPSRGWFELADAITAAGRDQQTHVVILRAEGRGFNAGVDIKEMQNTEGFTALIDA 79
Cdd:PRK06190   3 EPILLVETHDRVRTLTLNRPEArNALSAALRRALFAALAEADADDDVDVVVLTGADPAFCAGLDLKELGGDGSAYGAQDA 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  80 NRGCyeaFRAVYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERGAL---GAATHLSRLVPQHMMRRLF 156
Cdd:PRK06190  83 LPNP---SPAWPAMRKPVIGAINGAAVTGGLELALACDILIASERARFADTHARVGILpgwGLSVRLPQKVGIGRARRMS 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884 157 FTAATVDAHTLHHFGSVHEVVPRAELDEAALRVARDIAAKDTRVIRAAKEALNFIDVQRVNSSYRMEQGFTFELNLAGVA 236
Cdd:PRK06190 160 LTGDFLDAADALRAGLVTEVVPHDELLPRARRLAASIAGNNPAAVRALKASYDDGAAAQTGDALALEAEAARAHNRSVSP 239

                        250
                 ....*....|....*..
gi 490023884 237 DEHRDAFAG-TNKGKKQ 252
Cdd:PRK06190 240 DGIAARREAvMARGRAQ 256
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
 1-209 2.19e-32

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 118.82  E-value: 2.19e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   1 MPITTTSPEPGIVSVTVDYP-PVNAIPSRGWFELADAITAAGRDQQTHVVILRAEGRGFNAGVDIKEMQNTEGftALIDA 79
Cdd:PRK06688   4 VTDLLVELEDGVLTITINRPdKKNALTAAMYQALADALEAAATDPAVRVVVLTGAGRAFSAGGDIKDFPKAPP--KPPDE 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  80 NRGCYEAFRAVYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERGAL---GAATHLSRLVPQHMMRRLF 156
Cdd:PRK06688  82 LAPVNRFLRAIAALPKPVVAAVNGPAVGVGVSLALACDLVYASESAKFSLPFAKLGLCpdaGGSALLPRLIGRARAAEML 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 490023884 157 FTAATVDAHTLHHFGSVHEVVPRAELDEAALRVARDIAAKDTRVIRAAKEALN 209
Cdd:PRK06688 162 LLGEPLSAEEALRIGLVNRVVPAAELDAEADAQAAKLAAGPASALRYTKRAIN 214
PRK06494 PRK06494
enoyl-CoA hydratase; Provisional
 11-208 1.58e-31

enoyl-CoA hydratase; Provisional


Pssm-ID: 180591 [Multi-domain]  Cd Length: 259  Bit Score: 116.68  E-value: 1.58e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  11 GIVSVTVDYPPV-NAIPSRGWFELADAITAAGRDQQTHVVILRAEG-RGFNAGVDIKEMQ-------NTEGFTALIDAnr 81
Cdd:PRK06494  13 HVTIVTLNRPEVmNALHLDAHFELEEVFDDFAADPEQWVAIVTGAGdKAFSAGNDLKEQAaggkrgwPESGFGGLTSR-- 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  82 gcyeafravYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERGALGAATHLSRLVPQHMMRR---LFFT 158
Cdd:PRK06494  91 ---------FDLDKPIIAAVNGVAMGGGFELALACDLIVAAENATFALPEPRVGLAALAGGLHRLPRQIGLKRamgMILT 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 490023884 159 AATVDAHTLHHFGSVHEVVPRAELDEAALRVARDIAAKDTRVIRAAKEAL 208
Cdd:PRK06494 162 GRRVTAREGLELGFVNEVVPAGELLAAAERWADDILACSPLSIRASKQAV 211
PRK06143 PRK06143
enoyl-CoA hydratase; Provisional
 6-208 5.16e-31

enoyl-CoA hydratase; Provisional


Pssm-ID: 180423  Cd Length: 256  Bit Score: 115.13  E-value: 5.16e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   6 TSPEPGIVSVTV-DYPPVNAIPSRGWFELADAITAAGRDQQTHVVILRAEG-RGFNAGVDIKEMQ--NTEGFTALIDANR 81
Cdd:PRK06143  11 TRDDRGVATLTIrNAGSLNILGTPVILALTQALRWLAADPDVRVLVLRGAGeKAFIGGADIKEMAtlDQASAEAFISRLR 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  82 GCYEAFRavyECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERG--ALGAATHLSRLVPQHMMRRLFFTA 159
Cdd:PRK06143  91 DLCDAVR---HFPVPVIARIPGWCLGGGLELAAACDLRIAAHDAQFGMPEVRVGipSVIHAALLPRLIGWARTRWLLLTG 167

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 490023884 160 ATVDAHTLHHFGSVHEVVPRAELDEAALRVARDIAAKDTRVIRAAKEAL 208
Cdd:PRK06143 168 ETIDAAQALAWGLVDRVVPLAELDAAVERLAASLAGCGPQALRQQKRLL 216
PRK03580 PRK03580
crotonobetainyl-CoA hydratase;
2-226 6.07e-30

crotonobetainyl-CoA hydratase;


Pssm-ID: 179599 [Multi-domain]  Cd Length: 261  Bit Score: 112.48  E-value: 6.07e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   2 PITTTSpEPGIVSVTVDYPPVNAIPSRGWFELADAITAAGRDQQTHVVILRAEG-RGFNAGVDIKEMQNTEGFTAliDAN 80
Cdd:PRK03580   4 SLHTTR-NGSILEITLDRPKANAIDAKTSFAMGEVFLNFRDDPELRVAIITGAGeKFFSAGWDLKAAAEGEAPDA--DFG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  81 RGCYEAFRAVYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERGAL---GAATHLSRLVPQHMMRRLFF 157
Cdd:PRK03580  81 PGGFAGLTEIFDLDKPVIAAVNGYAFGGGFELALAADFIVCADNASFALPEAKLGIVpdsGGVLRLPKRLPPAIANEMVM 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 490023884 158 TAATVDAHTLHHFGSVHEVVPRAELDEAALRVARDIAAKDTRVIRAAKEalnfidVQRVNSSYRMEQGF 226
Cdd:PRK03580 161 TGRRMDAEEALRWGIVNRVVPQAELMDRARELAQQLVNSAPLAIAALKE------IYRETSEMPVEEAY 223
PRK06142 PRK06142
crotonase/enoyl-CoA hydratase family protein;
11-221 1.94e-29

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235714  Cd Length: 272  Bit Score: 111.60  E-value: 1.94e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  11 GIVSVTVDYP-PVNAIPSRGWFELADAITAAGRDQQTHVVILRAEGRGFNAGVDIKEMQNTEG----------FTALIDA 79
Cdd:PRK06142  15 HVAQVTLNRPgKGNAMNPAFWSELPEIFRWLDADPEVRAVVLSGSGKHFSYGIDLPAMAGVFGqlgkdglarpRTDLRRE 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  80 NRGCYEAFRAVYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERGA---LGAATHLSRLVPQHMMRRLF 156
Cdd:PRK06142  95 ILRLQAAINAVADCRKPVIAAVQGWCIGGGVDLISACDMRYASADAKFSVREVDLGMvadVGSLQRLPRIIGDGHLRELA 174

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 490023884 157 FTAATVDAHTLHHFGSVHEVVPRAE-LDEAALRVARDIAAKDTRVIRAAKEALNFIDVQRVNSSYR 221
Cdd:PRK06142 175 LTGRDIDAAEAEKIGLVNRVYDDADaLLAAAHATAREIAAKSPLAVRGTKEVLDYMRDHRVADGLR 240
PRK08139 PRK08139
enoyl-CoA hydratase; Validated
 2-207 4.22e-29

enoyl-CoA hydratase; Validated


Pssm-ID: 181249  Cd Length: 266  Bit Score: 110.42  E-value: 4.22e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   2 PITTTSPEPGIVSVTVDYPP-VNAIPSRGWFELADAITAAGRDQQTHVVILRAEGRGFNAGVDIKEMQNTEGFTALIDAN 80
Cdd:PRK08139  11 PLLLREDRDGVATLTLNRPQaFNALSEAMLAALQAALDAIAADPSVRVVVLAAAGKAFCAGHDLKEMRAARGLAYFRALF 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  81 RGCYEAFRAVYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERGaLGAAT---HLSRLVP-QHMMRRLf 156
Cdd:PRK08139  91 ARCSRVMQAIVALPQPVIARVHGIATAAGCQLVASCDLAVAADTARFAVPGVNIG-LFCSTpmvALSRNVPrKQAMEML- 168

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 490023884 157 FTAATVDAHTLHHFGSVHEVVPRAELDEAALRVARDIAAKDTRVIRAAKEA 207
Cdd:PRK08139 169 LTGEFIDAATAREWGLVNRVVPADALDAAVARLAAVIAAKSPAAVRIGKEA 219
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
 9-245 5.41e-29

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 110.11  E-value: 5.41e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   9 EPGIVSVTVDYPPVNAIPSRGWFELADAITAAGRDQQTHVVILRAEGRGFNAGVDIKE---MQNTEGFTALidANRGcYE 85
Cdd:PRK07658   9 EDHVAVITLNHPPANALSSQVLHELSELLDQVEKDDNVRVVVIHGEGRFFSAGADIKEftsVTEAEQATEL--AQLG-QV 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  86 AFRAVYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERG---ALGAATHLSRLVPQHMMRRLFFTAATV 162
Cdd:PRK07658  86 TFERVEKFSKPVIAAIHGAALGGGLELAMSCHIRFATESAKLGLPELNLGlipGFAGTQRLPRYVGKAKALEMMLTSEPI 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884 163 DAHTLHHFGSVHEVVPRAELDEAALRVARDIAAKDTRVIRAAKEALNFidvqrvNSSYRMEQGFTFELNLAGVADEHRDA 242
Cdd:PRK07658 166 TGAEALKWGLVNGVFPEETLLDDAKKLAKKIAGKSPATTRAVLELLQT------TKSSSYYEGVKREAKIFGEVFTSEDA 239


                 ...
gi 490023884 243 FAG 245
Cdd:PRK07658 240 KEG 242
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 11-234 1.40e-28

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 108.60  E-value: 1.40e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   11 GIVSVTVDYP-PVNAIPSRGWFELADAITAAGRDQQTHVVILRAEGRGFNAGVDIKEMQN-TEGFTALIDANrgCYEAFR 88
Cdd:pfam00378   5 GVAVITLNRPeAVNALSAELITELIQALEKLRTDPSVRAVVLTGGDKAFCAGADLKEMYGeGPAHQALYREN--VLDLWT 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   89 AVYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERG---ALGAATHLSRLVPQHMMRRLFFTAATVDAH 165
Cdd:pfam00378  83 LLYTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGiipGAGGTDRLPRIIGHSKAMEMLLLGRRISAQ 162

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 490023884  166 TLHHFGSVHEVVPRAELDEAALRVARDIAAKDTRVIRAAKEALNfidvqrVNSSYRMEQGFTFELNLAG 234
Cdd:pfam00378 163 EALKWGLVDKVVPEDQLLDEARELAEKLAEKSPAALAQLKKALN------AKLEDALPTQLEAEARLFY 225
PRK06144 PRK06144
enoyl-CoA hydratase; Provisional
 1-209 1.11e-26

enoyl-CoA hydratase; Provisional


Pssm-ID: 180424 [Multi-domain]  Cd Length: 262  Bit Score: 103.92  E-value: 1.11e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   1 MPITTTSPE------PGIVSVTVDYPPV-NAIPSRGWFELADAITAAGRDQQTHVVILR-AEGRGFNAGVDIKEMQNTEG 72
Cdd:PRK06144   1 MAMTTSTDElllevrGGIARITFNRPAArNAMTWAMYEGLAEICEAIAADPSIRAVVLRgAGDKAFVAGTDIAQFRAFST 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  73 FTALIDANRGCYEAFRAVYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPeVERgALG---AATHLSRLV-- 147
Cdd:PRK06144  81 AEDAVAYERRIDRVLGALEQLRVPTIAAIAGACVGGGAAIAAACDLRIATPSARFGFP-IAR-TLGnclSMSNLARLVal 158

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 490023884 148 --PQhMMRRLFFTAATVDAHTLHHFGSVHEVVPRAELDEAALRVARDIAAKDTRVIRAAKEALN 209
Cdd:PRK06144 159 lgAA-RVKDMLFTARLLEAEEALAAGLVNEVVEDAALDARADALAELLAAHAPLTLRATKEALR 221
PRK05809 PRK05809
short-chain-enoyl-CoA hydratase;
9-209 1.12e-26

short-chain-enoyl-CoA hydratase;


Pssm-ID: 180270 [Multi-domain]  Cd Length: 260  Bit Score: 104.06  E-value: 1.12e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   9 EPGIVSVTVDYP-PVNAIPSRGWFELADAITAAGRDQQTHVVILRAEG-RGFNAGVDIKEMQN---TEGFTALIDANRgc 83
Cdd:PRK05809  11 EGHIAVVTINRPkALNALNSETLKELDTVLDDIENDDNVYAVILTGAGeKAFVAGADISEMKDlneEEGRKFGLLGNK-- 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  84 yeAFRAVYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERG---ALGAATHLSRLVPQHMMRRLFFTAA 160
Cdd:PRK05809  89 --VFRKLENLDKPVIAAINGFALGGGCELSMACDIRIASEKAKFGQPEVGLGitpGFGGTQRLARIVGPGKAKELIYTGD 166

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 490023884 161 TVDAHTLHHFGSVHEVVPRAELDEAALRVARDIAAKDTRVIRAAKEALN 209
Cdd:PRK05809 167 MINAEEALRIGLVNKVVEPEKLMEEAKALANKIAANAPIAVKLCKDAIN 215
PRK06127 PRK06127
enoyl-CoA hydratase; Provisional
 23-208 2.54e-26

enoyl-CoA hydratase; Provisional


Pssm-ID: 235705  Cd Length: 269  Bit Score: 103.25  E-value: 2.54e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  23 NAIPSRGWFELADAITAAGRDQQTHVVILRAEG-RGFNAGVDIKEMQNTEGFTALIDA-NRGCYEAFRAVYECAVPVVAA 100
Cdd:PRK06127  33 NAMSLDMWEALPQALAAAEDDDAIRVVVLTGAGeKAFVSGADISQFEESRSDAEAVAAyEQAVEAAQAALADYAKPTIAC 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884 101 VNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERG---ALGAATHLSRLVPQHMMRRLFFTAATVDAHTLHHFGSVHEVV 177
Cdd:PRK06127 113 IRGYCIGGGMGIALACDIRIAAEDSRFGIPAARLGlgyGYDGVKNLVDLVGPSAAKDLFYTARRFDAAEALRIGLVHRVT 192

                        170       180       190
                 ....*....|....*....|....*....|.
gi 490023884 178 PRAELDEAALRVARDIAAKDTRVIRAAKEAL 208
Cdd:PRK06127 193 AADDLETALADYAATIAGNAPLTLRAAKRAI 223
PRK08290 PRK08290
enoyl-CoA hydratase; Provisional
 5-209 8.69e-26

enoyl-CoA hydratase; Provisional


Pssm-ID: 236220 [Multi-domain]  Cd Length: 288  Bit Score: 101.96  E-value: 8.69e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   5 TTSPEPGIVSVTVDYPPV-NAIPSRGWFELADAITAAGRDQQTHVVILRAEGRGFNAGVDIK------EMQNTEGFTALI 77
Cdd:PRK08290   7 RYEVAGRIARITLNRPEArNAQNRQMLYELDAAFRRAEADDAVRVIVLAGAGKHFSAGHDLGsgtpgrDRDPGPDQHPTL 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  78 DANRGCYEA--FRAVYECAV-------------PVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERGALGAATH 142
Cdd:PRK08290  87 WWDGATKPGveQRYAREWEVylgmcrrwrdlpkPTIAQVQGACIAGGLMLAWVCDLIVASDDAFFSDPVVRMGIPGVEYF 166

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 490023884 143 lsrlVPQHMM-----RRLFFTAATVDAHTLHHFGSVHEVVPRAELDEAALRVARDIAAKDTRVIRAAKEALN 209
Cdd:PRK08290 167 ----AHPWELgprkaKELLFTGDRLTADEAHRLGMVNRVVPRDELEAETLELARRIAAMPPFGLRLTKRAVN 234
PRK09120 PRK09120
p-hydroxycinnamoyl CoA hydratase/lyase; Validated
 32-252 3.60e-24

p-hydroxycinnamoyl CoA hydratase/lyase; Validated


Pssm-ID: 236383  Cd Length: 275  Bit Score: 97.39  E-value: 3.60e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  32 ELADAITAAGRDQQTHVVILRAEGRGFNAGVDIKE-MQNTE--GFTALIDANRGCYEAFRAVYECAVPVVAAVNGFCVGG 108
Cdd:PRK09120  39 EMIDVLDALEFDDDAGVLVLTGAGDAWSAGMDLKEyFRETDaqPEILQERIRREAYGWWRRLRWYQKPTIAMVNGWCFGG 118

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884 109 GIGLVGNSDVIVASDDAKFGLPEVERGAL---GAATHLSRLVPQ-----HMMrrlffTAATVDAHTLHHFGSVHEVVPRA 180
Cdd:PRK09120 119 GFSPLVACDLAIAADEAQFGLSEINWGIPpggGVSKAMADTVGHrdalyYIM-----TGETFTGRKAAEMGLVNESVPLA 193

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 490023884 181 ELDEAALRVARDIAAKDTRVIRAAKEAlnfidvqrvnssYRMEQGFTFELNL-----AGVADEHRDAFAGTNKGKKQ 252
Cdd:PRK09120 194 QLRARTRELAAKLLEKNPVVLRAAKDG------------FKRVRELTWDQAEdylyaKLEQANSLDPEGGREEGLKQ 258
PRK08138 PRK08138
enoyl-CoA hydratase; Provisional
 8-195 3.91e-24

enoyl-CoA hydratase; Provisional


Pssm-ID: 236162 [Multi-domain]  Cd Length: 261  Bit Score: 97.04  E-value: 3.91e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   8 PEPGIVSVTVDYPPV-NAIPSRGWFELADAITAAGRDQQTHVVILRAEGRGFNAGVDIKEMQNTegfTALIDANRGCYEA 86
Cdd:PRK08138  14 PADGVALLRLNRPEArNALNMEVRQQLAEHFTELSEDPDIRAIVLTGGEKVFAAGADIKEFATA---GAIEMYLRHTERY 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  87 FRAVYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERGAL---GAATHLSRLVPQHMMRRLFFTAATVD 163
Cdd:PRK08138  91 WEAIAQCPKPVIAAVNGYALGGGCELAMHADIIVAGESASFGQPEIKVGLMpgaGGTQRLVRAVGKFKAMRMALTGCMVP 170

                        170       180       190
                 ....*....|....*....|....*....|..
gi 490023884 164 AHTLHHFGSVHEVVPRAELDEAALRVARDIAA 195
Cdd:PRK08138 171 APEALAIGLVSEVVEDEQTLPRALELAREIAR 202
PRK09245 PRK09245
crotonase/enoyl-CoA hydratase family protein;
1-208 4.84e-24

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181723  Cd Length: 266  Bit Score: 96.96  E-value: 4.84e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   1 MPITTTSPEPGIVSVTVDYPPV-NAIPSRGWF-ELADAITAAGRDQQTHVVILRAEGRGFNAGVDIKEMQNTEG-FTALI 77
Cdd:PRK09245   2 TDFLLVERDGHIVTLTMNRPETrNALSDNDAVdALVAACAAINADRSVRAVILTGAGTAFSSGGNVKDMRARVGaFGGSP 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  78 DANRGCYEA-----FRAVYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERGAL---GAATHLSRLVPQ 149
Cdd:PRK09245  82 ADIRQGYRHgiqriPLALYNLEVPVIAAVNGPAIGAGCDLACMCDIRIASETARFAESFVKLGLIpgdGGAWLLPRIIGM 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 490023884 150 HMMRRLFFTAATVDAHTLHHFGSVHEVVPRAELDEAALRVARDIAAKDTRVIRAAKEAL 208
Cdd:PRK09245 162 ARAAEMAFTGDAIDAATALEWGLVSRVVPADQLLPAARALAERIAANPPHALRLTKRLL 220
PRK05862 PRK05862
enoyl-CoA hydratase; Provisional
 23-209 2.79e-23

enoyl-CoA hydratase; Provisional


Pssm-ID: 180295 [Multi-domain]  Cd Length: 257  Bit Score: 94.72  E-value: 2.79e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  23 NAIPSRGWFELADAITAAGRDQQTHVVILRAEGRGFNAGVDIKEMQNTEgftaLIDANRGCY-EAFRAVYECAVPVVAAV 101
Cdd:PRK05862  26 NALNDALMDELGAALAAFDADEGIGAIVITGSEKAFAAGADIKEMADLS----FMDVYKGDYiTNWEKVARIRKPVIAAV 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884 102 NGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERGAL---GAATHLSRLVPQHMMRRLFFTAATVDAHTLHHFGSVHEVVP 178
Cdd:PRK05862 102 AGYALGGGCELAMMCDIIIAADTAKFGQPEIKLGVLpgmGGSQRLTRAVGKAKAMDLCLTGRMMDAAEAERAGLVSRVVP 181

                        170       180       190
                 ....*....|....*....|....*....|.
gi 490023884 179 RAELDEAALRVARDIAAKDTRVIRAAKEALN 209
Cdd:PRK05862 182 ADKLLDEALAAATTIASFSLPAVMMAKEAVN 212
PRK07468 PRK07468
crotonase/enoyl-CoA hydratase family protein;
11-185 5.45e-23

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180987 [Multi-domain]  Cd Length: 262  Bit Score: 93.97  E-value: 5.45e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  11 GIVSVTVDYPPV-NAIPSRGWFELADAITAAGRDQQTHVVILRAEGRGFNAGVDIKEMQntEGFTA----LIDANRGCYE 85
Cdd:PRK07468  14 GVATLTLNRPEKhNALSARMIAELTTAARRLAADAAVRVVVLTGAGKSFCAGGDLGWMR--AQMTAdratRIEEARRLAM 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  86 AFRAVYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERGALGA--ATHLSRLVPQHMMRRLFFTAATVD 163
Cdd:PRK07468  92 MLKALNDLPKPLIGRIQGQAFGGGVGLISVCDVAIAVSGARFGLTETRLGLIPAtiSPYVVARMGEANARRVFMSARLFD 171

                        170       180
                 ....*....|....*....|..
gi 490023884 164 AHTLHHFGSVHEVVPRAELDEA 185
Cdd:PRK07468 172 AEEAVRLGLLSRVVPAERLDAA 193
PRK11423 PRK11423
methylmalonyl-CoA decarboxylase; Provisional
 1-229 5.65e-23

methylmalonyl-CoA decarboxylase; Provisional


Pssm-ID: 236908 [Multi-domain]  Cd Length: 261  Bit Score: 93.94  E-value: 5.65e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   1 MPITTTSPEPGIVSVTVDYPP-VNAIPSrgwfELADAITAAGRDQQTH---VVILRAEGRG--FNAGVDIKEmqntegft 74
Cdd:PRK11423   3 MQYVNVVTINKIATITFNNPAkRNALSK----VLIDDLMQALSDLNRPeirVVILRAPSGSkvWSAGHDIHE-------- 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  75 aLIDANRGCYE-------AFRAVYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKF-------GLPEVERGALgaa 140
Cdd:PRK11423  71 -LPSGGRDPLSyddplrqILRMIQKFPKPVIAMVEGSVWGGAFELIMSCDLIIAASTSTFamtpanlGVPYNLSGIL--- 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884 141 tHLSRLVPQHMMRRLFFTAATVDAHTLHHFGSVHEVVPRAELDEAALRVARDIAAKDTRVIRAAKEALnfidvqRVNSSY 220
Cdd:PRK11423 147 -NFTNDAGFHIVKEMFFTASPITAQRALAVGILNHVVEVEELEDFTLQMAHHISEKAPLAIAVIKEQL------RVLGEA 219


                 ....*....
gi 490023884 221 RMEQGFTFE 229
Cdd:PRK11423 220 HPMNPDEFE 228
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
 9-209 7.55e-23

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 93.65  E-value: 7.55e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   9 EPGIVSVTVDYP-PVNAIPSRGWFELADAITAAGRDQQTHVVILRAEG-RGFNAGVDIKE---MQNTE--GFTALIDanr 81
Cdd:PRK07657  11 TPHVVKITLNRPrAANALSLALLEELQNILTQINEEANVRVVILTGAGeKAFCAGADLKEragMNEEQvrHAVSLIR--- 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  82 gcyEAFRAVYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERGAL---GAATHLSRLVPQHMMRRLFFT 158
Cdd:PRK07657  88 ---TTMEMVEQLPQPVIAAINGIALGGGLELALACDFRIAAESASLGLTETTLAIIpgaGGTQRLPRLIGVGRAKELIYT 164

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 490023884 159 AATVDAHTLHHFGSVHEVVPRAELDEAALRVARDIAAKDTRVIRAAKEALN 209
Cdd:PRK07657 165 GRRISAQEAKEIGLVEFVVPAHLLEEKAIEIAEKIASNGPIAVRQAKEAIS 215
PRK08252 PRK08252
crotonase/enoyl-CoA hydratase family protein;
11-206 1.18e-21

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181325 [Multi-domain]  Cd Length: 254  Bit Score: 90.43  E-value: 1.18e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  11 GIVSVTVDYPPV-NAIPsrgwFELADAITAA----GRDQQTHVVILRAEGRGFNAGVDIK-----EMQNTEGftalidan 80
Cdd:PRK08252  12 RVLIITINRPEArNAVN----AAVAQGLAAAldelDADPDLSVGILTGAGGTFCAGMDLKafargERPSIPG-------- 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  81 RGcyeaFRAVYECAV--PVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERGALGAATHLSRL---VPQHMMRRL 155
Cdd:PRK08252  80 RG----FGGLTERPPrkPLIAAVEGYALAGGFELALACDLIVAARDAKFGLPEVKRGLVAAGGGLLRLprrIPYHIAMEL 155

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 490023884 156 FFTAATVDAHTLHHFGSVHEVVPRAELDEAALRVARDIAAKDTRVIRAAKE 206
Cdd:PRK08252 156 ALTGDMLTAERAHELGLVNRLTEPGQALDAALELAERIAANGPLAVAASKR 206
PRK06563 PRK06563
crotonase/enoyl-CoA hydratase family protein;
23-207 3.26e-21

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180625 [Multi-domain]  Cd Length: 255  Bit Score: 89.25  E-value: 3.26e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  23 NAIPSRGWFELADAITAAGRDQQTHVVILRAEGRGFNAGVDIKEMQNTEGFTALIDANRGCYEAFRAVYECAVPVVAAVN 102
Cdd:PRK06563  21 NAFDSAMLDDLALALGEYEADDELRVAVLFAHGEHFTAGLDLADVAPKLAAGGFPFPEGGIDPWGTVGRRLSKPLVVAVQ 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884 103 GFCVGGGIGLVGNSDVIVASDDAKFGLPEVERG--ALGAAThlSRLvPQHM-----MRRLfFTAATVDAHTLHHFGSVHE 175
Cdd:PRK06563 101 GYCLTLGIELMLAADIVVAADNTRFAQLEVQRGilPFGGAT--LRF-PQAAgwgnaMRYL-LTGDEFDAQEALRLGLVQE 176

                        170       180       190
                 ....*....|....*....|....*....|..
gi 490023884 176 VVPRAELDEAALRVARDIAAKDTRVIRAAKEA 207
Cdd:PRK06563 177 VVPPGEQLERAIELAERIARAAPLGVQATLAS 208
PLN02600 PLN02600
enoyl-CoA hydratase
 8-209 6.55e-21

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 88.32  E-value: 6.55e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   8 PEPGIVSVTVDYPPV-NAIPSRGWFELADAITAAGRDQQTHVVILRAEGRG-FNAGVDIKE---MQNTEGFTaLIDANRG 82
Cdd:PLN02600   1 PDSGIVELRLDRPEAkNAIGKEMLRGLRSAFEKIQADASARVVMLRSSVPGvFCAGADLKErrkMSPSEVQK-FVNSLRS 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  83 CYEAFRAVyecAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPE----VERGAlGAATHLSRLVPQHMMRRLFFT 158
Cdd:PLN02600  80 TFSSLEAL---SIPTIAVVEGAALGGGLELALSCDLRICGEEAVFGLPEtglaIIPGA-GGTQRLPRLVGRSRAKELIFT 155

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 490023884 159 AATVDAHTLHHFGSVHEVVPRAELDEAALRVARDIAAKDTRVIRAAKEALN 209
Cdd:PLN02600 156 GRRIGAREAASMGLVNYCVPAGEAYEKALELAQEINQKGPLAIKMAKKAIN 206
PRK08272 PRK08272
crotonase/enoyl-CoA hydratase family protein;
5-209 1.12e-20

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236213  Cd Length: 302  Bit Score: 88.56  E-value: 1.12e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   5 TTSPEPGIVSVTVDYPPV-NAIPSRGWFELADAITAAGRDQQTHVVILRAEGRGFNAGVDIK---EMQNTEGFTALIDAN 80
Cdd:PRK08272  13 TYEVTGRIARITLNRPEKgNAITADTPLELRAAVERADLDPGVHVILVSGAGKGFCAGYDLSayaEGSSSGGGGGAYPGK 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  81 R--------GCY-------------EAFRAVYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVErgALGA 139
Cdd:PRK08272  93 RqavnhlpdDPWdpmidyqmmsrfvRGFMSLWHAHKPTVAKVHGYCVAGGTDIALHCDQVIAADDAKIGYPPTR--VWGV 170

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 490023884 140 -ATHL--SRLVPQHmMRRLFFTAATVDAHTLHHFGSVHEVVPRAELDEAALRVARDIAAKDTRVIRAAKEALN 209
Cdd:PRK08272 171 pATGMwaYRLGPQR-AKRLLFTGDCITGAQAAEWGLAVEAVPPEELDERTERLVERIAAVPVNQLAMVKLAVN 242
PLN02888 PLN02888
enoyl-CoA hydratase
 2-209 2.36e-20

enoyl-CoA hydratase


Pssm-ID: 215480  Cd Length: 265  Bit Score: 87.11  E-value: 2.36e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   2 PITTTSPEPGIVSVTVDYP-PVNAIPSRGWFELADAITAAGRDQQTHVVILRAEGRGFNAGVDIKEMQNT-EGFTALIDA 79
Cdd:PLN02888  10 LILVPKSRNGIATITINRPkALNALTRPMMVELAAAFKRLDEDDSVKVIILTGSGRAFCSGVDLTAAEEVfKGDVKDVET 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  80 NrgcyeafrAVYE---CAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERG---ALGAATHLSRLVPQHMMR 153
Cdd:PLN02888  90 D--------PVAQmerCRKPIIGAINGFAITAGFEIALACDILVASRGAKFIDTHAKFGifpSWGLSQKLSRIIGANRAR 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 490023884 154 RLFFTAATVDAHTLHHFGSVHEVVPRAELDEAALRVARDIAAKDTRVIRAAKEALN 209
Cdd:PLN02888 162 EVSLTAMPLTAETAERWGLVNHVVEESELLKKAREVAEAIIKNNQGMVLRYKSVIN 217
PRK07509 PRK07509
crotonase/enoyl-CoA hydratase family protein;
11-209 4.34e-20

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181008 [Multi-domain]  Cd Length: 262  Bit Score: 86.09  E-value: 4.34e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  11 GIVSVTVDYP-PVNAIPSRGWFELADAITAAGRDQQTHVVILRAEGRGFNAGVDIKEMQNTEG--FTALI-----DANRG 82
Cdd:PRK07509  12 GIADVRLNRPdKMNALDFAMFEELIATIKRLKKDRGIRAVILSGEGGAFCAGLDVKSVASSPGnaVKLLFkrlpgNANLA 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  83 CYeAFRAVYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERGA---LGAATHLSRLVPQHMMRRLFFTA 159
Cdd:PRK07509  92 QR-VSLGWRRLPVPVIAALEGVCFGGGLQIALGADIRIAAPDTKLSIMEAKWGLvpdMAGTVSLRGLVRKDVARELTYTA 170

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 490023884 160 ATVDAHTLHHFGSVHEVV--PRAeldeAALRVARDIAAKDTRVIRAAKEALN 209
Cdd:PRK07509 171 RVFSAEEALELGLVTHVSddPLA----AALALAREIAQRSPDAIAAAKRLIN 218
PRK07327 PRK07327
enoyl-CoA hydratase/isomerase family protein;
8-233 2.72e-19

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 235991  Cd Length: 268  Bit Score: 84.30  E-value: 2.72e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   8 PEPGIVSVTVDYPPV-NAIPSRGWFELADAITAAGRDQQTHVVILRAEGRGFNAGVDIKEMQNTEG-FTALIDANRgcyE 85
Cdd:PRK07327  18 PPPGVLEIVLNGPGAlNAADARMHRELADIWRDVDRDPDVRVVLIRGEGKAFSAGGDLALVEEMADdFEVRARVWR---E 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  86 AFRAVY---ECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERGaLGAATHLSRLVP---------QHMMr 153
Cdd:PRK07327  95 ARDLVYnviNCDKPIVSAIHGPAVGAGLVAALLADISIAAKDARIIDGHTRLG-VAAGDHAAIVWPllcgmakakYYLL- 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884 154 rlffTAATVDAHTLHHFGSVHEVVPRAELDEAALRVARDIAAKDTRVIRAAKEALnfidvqrvNSSYRMeQGFTFELNLA 233
Cdd:PRK07327 173 ----LCEPVSGEEAERIGLVSLAVDDDELLPKALEVAERLAAGSQTAIRWTKYAL--------NNWLRM-AGPTFDTSLA 239
PRK05869 PRK05869
enoyl-CoA hydratase; Validated
 7-209 2.92e-18

enoyl-CoA hydratase; Validated


Pssm-ID: 235632 [Multi-domain]  Cd Length: 222  Bit Score: 80.65  E-value: 2.92e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   7 SPEPGIVSVTVDYPPVNAIPSRGWFELADAITAAGRDQQTHVVILRAEGRGFNAGVDIKEMQNTEGFTALIdANRGCYEA 86
Cdd:PRK05869  13 SQDAGLATLLLSRPPTNALTRQVYREIVAAANELGRRDDVAAVILYGGHEIFSAGDDMPELRTLSAQEADT-AARVRQQA 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  87 FRAVYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERG---ALGAATHLSRLVPQHMMRRLFFTAATVD 163
Cdd:PRK05869  92 VDAVAAIPKPTVAAITGYALGAGLTLALAADWRVSGDNVKFGATEILAGlapSGDGMARLTRAAGPSRAKELVFSGRFFD 171

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 490023884 164 AHTLHHFGSVHEVVPRAELDEAALRVARDIAAKDTRVIRAAKEALN 209
Cdd:PRK05869 172 AEEALALGLIDEMVAPDDVYDAAAAWARRFLDGPPHALAAAKAGIS 217
PRK08321 PRK08321
1,4-dihydroxy-2-naphthoyl-CoA synthase;
9-243 4.76e-18

1,4-dihydroxy-2-naphthoyl-CoA synthase;


Pssm-ID: 181386  Cd Length: 302  Bit Score: 81.22  E-value: 4.76e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   9 EPGIVSVTVDYPPV-NAIPSRGWFELADAITAAGRDQQTHVVIL-------RAEGRGFNAGVDIK-----EMQNTEGFTA 75
Cdd:PRK08321  32 DQGTVRIAFDRPEVrNAFRPHTVDELYRALDHARMSPDVGCVLLtgngpspKDGGWAFCSGGDQRirgrdGYQYAEGDEA 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  76 -LIDANRG----CYEAFRAVYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDD-AKFGL--PEVER--GALGAAtHLSR 145
Cdd:PRK08321 112 dTVDPARAgrlhILEVQRLIRFMPKVVIAVVPGWAAGGGHSLHVVCDLTLASREhARFKQtdADVGSfdGGYGSA-YLAR 190

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884 146 LVPQHMMRRLFFTAATVDAHTLHHFGSVHEVVPRAELDEAALRVARDIAAKDTRVIRAAKEALNFIDVQRVNssyrmEQG 225
Cdd:PRK08321 191 QVGQKFAREIFFLGRTYSAEEAHDMGAVNAVVPHAELETEALEWAREINGKSPTAMRMLKYAFNLTDDGLVG-----QQL 265

                        250       260
                 ....*....|....*....|..
gi 490023884 226 FTFELN-LAGVADEH---RDAF 243
Cdd:PRK08321 266 FAGEATrLAYMTDEAqegRDAF 287
PLN02921 PLN02921
naphthoate synthase
 11-212 5.24e-18

naphthoate synthase


Pssm-ID: 178509 [Multi-domain]  Cd Length: 327  Bit Score: 81.76  E-value: 5.24e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  11 GIVSVTVDYPPV-NAIPSRGWFELADAITAAGRDQQTHVVILRAEG-RGFNAGVDiKEMQNTEGFTALIDANR-GCYEAF 87
Cdd:PLN02921  76 GIAKITINRPERrNAFRPRTVKELQRAFNDARDDSSVGVIILTGKGtKAFCSGGD-QAVRGKDGYVGPDDAGRlNVLDLQ 154

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  88 RAVYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERGALGA---ATHLSRLVPQHMMRRLFFTAATVDA 164
Cdd:PLN02921 155 IQIRRLPKPVIAMVAGYAVGGGHILHMVCDLTIAADNAVFGQTGPKVGSFDAgygSSIMARLVGQKKAREMWFLARFYTA 234

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 490023884 165 HTLHHFGSVHEVVPRAELDEAALRVARDIAAKDTRVIRAAKEALNFID 212
Cdd:PLN02921 235 SEALKMGLVNTVVPLDELEGETVKWCREILRNSPTAIRVLKSALNAAD 282
PRK06210 PRK06210
enoyl-CoA hydratase; Provisional
 2-194 8.61e-18

enoyl-CoA hydratase; Provisional


Pssm-ID: 180472  Cd Length: 272  Bit Score: 80.13  E-value: 8.61e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   2 PITTTSPEPGIVSVTVDYPP-VNAIPSRGWFELADAITAAGRDQQTHVVILRAEGRGFNAGVDIKEMQNTEG-------F 73
Cdd:PRK06210   6 AVLYEVADSGVAVITLNRPDrLNAWTPVMEAEVYAAMDRAEADPAVRVIVLTGAGRGFCAGADMGELQTIDPsdgrrdtD 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  74 TALIDANRGCYEAFRAVYECAV--PVVAAVNGFCVggGIGLVGN--SDVIVASDDAKFGLPEVERGAL---GAATHLSRL 146
Cdd:PRK06210  86 VRPFVGNRRPDYQTRYHFLTALrkPVIAAINGACA--GIGLTHAlmCDVRFAADGAKFTTAFARRGLIaehGISWILPRL 163

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 490023884 147 VPQHMMRRLFFTAATVDAHTLHHFGSVHEVVPRAELDEAALRVARDIA 194
Cdd:PRK06210 164 VGHANALDLLLSARTFYAEEALRLGLVNRVVPPDELMERTLAYAEDLA 211
PRK07827 PRK07827
enoyl-CoA hydratase family protein;
1-205 1.09e-17

enoyl-CoA hydratase family protein;


Pssm-ID: 236109 [Multi-domain]  Cd Length: 260  Bit Score: 79.73  E-value: 1.09e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   1 MPITTTSPEPGIVSVTVDYPP-VNAIPSRGWFELADAITAAGRDQQTHVVILRAEGRGFNAGVDIKEM--QNTEGFTALI 77
Cdd:PRK07827   5 DTLVRYAVDGGVATLTLDSPHnRNALSARLVAQLHDGLRAAAADPAVRAVVLTHTGGTFCAGADLSEAggGGGDPYDAAV 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  78 DANRGCYEAFRAVYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERG---ALGAATHLSRLVPQhMMRR 154
Cdd:PRK07827  85 ARAREMTALLRAIVELPKPVIAAIDGHVRAGGFGLVGACDIVVAGPESTFALTEARIGvapAIISLTLLPRLSPR-AAAR 163

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 490023884 155 LFFTAATVDAHTLHHFGSVHEVVPraELDEAALRVARDIAAKDTRVIRAAK 205
Cdd:PRK07827 164 YYLTGEKFGAAEAARIGLVTAAAD--DVDAAVAALLADLRRGSPQGLAESK 212
PRK08260 PRK08260
enoyl-CoA hydratase; Provisional
 9-200 1.36e-17

enoyl-CoA hydratase; Provisional


Pssm-ID: 236206 [Multi-domain]  Cd Length: 296  Bit Score: 80.05  E-value: 1.36e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   9 EPGIVSVTVDYPP-VNAIPSRGWFELADAITAAGRDQQTHVVILRAEGRGFNAGVDIKEMQNTEGF-----TALIDANRG 82
Cdd:PRK08260  11 ADGIATITLNRPDkLNAFTVTMARELIEAFDAADADDAVRAVIVTGAGRAFCAGADLSAGGNTFDLdaprtPVEADEEDR 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  83 CYEAFRAV-----------YECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERGALGAATH---LSRLVP 148
Cdd:PRK08260  91 ADPSDDGVrdgggrvtlriFDSLKPVIAAVNGPAVGVGATMTLAMDIRLASTAARFGFVFGRRGIVPEAASswfLPRLVG 170

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 490023884 149 QHMMRRLFFTAATVDAHTLHHFGSVHEVVPRAELDEAALRVARDIAAKDTRV 200
Cdd:PRK08260 171 LQTALEWVYSGRVFDAQEALDGGLVRSVHPPDELLPAARALAREIADNTSPV 222
PRK05674 PRK05674
gamma-carboxygeranoyl-CoA hydratase; Validated
 32-208 1.63e-17

gamma-carboxygeranoyl-CoA hydratase; Validated


Pssm-ID: 168168  Cd Length: 265  Bit Score: 79.47  E-value: 1.63e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  32 ELADAITAAGRDQQTHVVILRAEGRGFNAGVDIKEMQNTEGF---TALIDAnRGCYEAFRAVYECAVPVVAAVNGFCVGG 108
Cdd:PRK05674  37 ELILALDQVQSDASLRFLLLRGRGRHFSAGADLAWMQQSADLdynTNLDDA-RELAELMYNLYRLKIPTLAVVQGAAFGG 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884 109 GIGLVGNSDVIVASDDAKFGLPEVERGALGA--ATHLSRLVPQHMMRRLFFTAATVDAHTLHHFGSVHEVVPRAELDEAA 186
Cdd:PRK05674 116 ALGLISCCDMAIGADDAQFCLSEVRIGLAPAviSPFVVKAIGERAARRYALTAERFDGRRARELGLLAESYPAAELEAQV 195

                        170       180
                 ....*....|....*....|..
gi 490023884 187 LRVARDIAAKDTRVIRAAKEAL 208
Cdd:PRK05674 196 EAWIANLLLNSPQALRASKDLL 217
PRK08150 PRK08150
crotonase/enoyl-CoA hydratase family protein;
23-195 1.98e-17

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181254  Cd Length: 255  Bit Score: 78.91  E-value: 1.98e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  23 NAIPSRGWFELADAITAAGRDqqTHVVILRAEGRGFNAGVDIKEMQNTEGFTALIDAnRGCYEAFRAVYECAVPVVAAVN 102
Cdd:PRK08150  24 NALNDGLIAALRAAFARLPEG--VRAVVLHGEGDHFCAGLDLSELRERDAGEGMHHS-RRWHRVFDKIQYGRVPVIAALH 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884 103 GFCVGGGIGLVGNSDVIVASDDAKFGLPEVERGAL---GAATHLSRLVPQHMMRRLFFTAATVDAHTLHHFGSVHEVVPR 179
Cdd:PRK08150 101 GAVVGGGLELASAAHIRVADESTYFALPEGQRGIFvggGGSVRVPRLIGVARMTDMMLTGRVYDAQEGERLGLAQYLVPA 180

                        170
                 ....*....|....*.
gi 490023884 180 AELDEAALRVARDIAA 195
Cdd:PRK08150 181 GEALDKAMELARRIAQ 196
PRK08258 PRK08258
enoyl-CoA hydratase family protein;
11-195 2.27e-17

enoyl-CoA hydratase family protein;


Pssm-ID: 181329  Cd Length: 277  Bit Score: 79.24  E-value: 2.27e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  11 GIVSVTVDYPP-VNAIPSRGWFELADAITAAGRDQQTHVVILRAEGRGFNAGVDIKE-------MQNTEgftaLIDANRG 82
Cdd:PRK08258  26 GVATITLNRPErKNPLTFESYAELRDLFRELVYADDVKAVVLTGAGGNFCSGGDVHEiigpltkMDMPE----LLAFTRM 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  83 CYEAFRAVYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKF-------GLPeverGA-LGAATHLSRLVPQHMMRR 154
Cdd:PRK08258 102 TGDLVKAMRACPQPIIAAVDGVCAGAGAILAMASDLRLGTPSAKTaflftrvGLA----GAdMGACALLPRIIGQGRASE 177

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 490023884 155 LFFTAATVDAHTLHHFGSVHEVVPRAELDEAALRVARDIAA 195
Cdd:PRK08258 178 LLYTGRSMSAEEGERWGFFNRLVEPEELLAEAQALARRLAA 218
PLN02664 PLN02664
enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase
 3-208 2.49e-17

enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase


Pssm-ID: 178269 [Multi-domain]  Cd Length: 275  Bit Score: 79.18  E-value: 2.49e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   3 ITTTSPEPGIVSVTVDYPPVNAIPSRGWF-ELADAITAAGRDQQTHVVILRAEGRGFNAGVDIKEMQNTEGFTALIDANR 81
Cdd:PLN02664   9 IIQKSPNSSVFHLNLNRPSQRNALSLDFFtEFPKALSSLDQNPNVSVIILSGAGDHFCSGIDLKTLNSISEQSSSGDRGR 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  82 G----------CYEAFRAVYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERGA---LGAATHLSRLVP 148
Cdd:PLN02664  89 SgerlrrkikfLQDAITAIEQCRKPVIAAIHGACIGGGVDIVTACDIRYCSEDAFFSVKEVDLAItadLGTLQRLPSIVG 168

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 490023884 149 QHMMRRLFFTAATVDAHTLHHFGSVHEVV-PRAELDEAALRVARDIAAKDTRVIRAAKEAL 208
Cdd:PLN02664 169 YGNAMELALTGRRFSGSEAKELGLVSRVFgSKEDLDEGVRLIAEGIAAKSPLAVTGTKAVL 229
PRK07511 PRK07511
enoyl-CoA hydratase; Provisional
 23-209 2.98e-16

enoyl-CoA hydratase; Provisional


Pssm-ID: 181009 [Multi-domain]  Cd Length: 260  Bit Score: 75.80  E-value: 2.98e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  23 NAIPSRGWFELADAITAAGRDQQTHVVILRAEGRGFNAGVDIKEMQNTEGFT-----ALIDANRGCYEAFRAvyeCAVPV 97
Cdd:PRK07511  25 NALHPDMYAAGIEALNTAERDPSIRAVVLTGAGGFFCAGGNLNRLLENRAKPpsvqaASIDGLHDWIRAIRA---FPKPV 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  98 VAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERGAL---GAATHLSRLVPQHMMRRLFFTAATVDAHTLHHFGSVH 174
Cdd:PRK07511 102 IAAVEGAAAGAGFSLALACDLLVAARDAKFVMAYVKVGLTpdgGGSWFLARALPRQLATELLLEGKPISAERLHALGVVN 181

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 490023884 175 EVVPRAELDEAALRVARDIAAKDTRVIRAAKEALN 209
Cdd:PRK07511 182 RLAEPGQALAEALALADQLAAGSPNALARIKSLIA 216
PRK05870 PRK05870
enoyl-CoA hydratase; Provisional
 11-208 4.40e-16

enoyl-CoA hydratase; Provisional


Pssm-ID: 180298  Cd Length: 249  Bit Score: 75.15  E-value: 4.40e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  11 GIVSVTVDYPP-VNAIPSRGWFELADAITAAGRDQQTHVVILRAEGRGFNAGVDIKEMQNTEGFTALiDANRGCYEAFRA 89
Cdd:PRK05870  12 GVALITVNDPDrRNAVTAEMSAQLRAAVAAAEADPDVHALVVTGAGKAFCAGADLTALGAAPGRPAE-DGLRRIYDGFLA 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  90 VYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERG---ALGAATHLSRLVPQHMMRRLFFTAATVDAHT 166
Cdd:PRK05870  91 VASCPLPTIAAVNGAAVGAGLNLALAADVRIAGPKALFDARFQKLGlhpGGGATWMLQRAVGPQVARAALLFGMRFDAEA 170

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 490023884 167 LHHFGSVHEVVPraELDEAALRVARDIAAKDTRVIRAAKEAL 208
Cdd:PRK05870 171 AVRHGLALMVAD--DPVAAALELAAGPAAAPRELVLATKASM 210
PRK07396 PRK07396
dihydroxynaphthoic acid synthetase; Validated
 11-209 1.16e-15

dihydroxynaphthoic acid synthetase; Validated


Pssm-ID: 180958 [Multi-domain]  Cd Length: 273  Bit Score: 74.16  E-value: 1.16e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  11 GIVSVTVDYPPV-NAIPSRGWFELADAITAAGRDQQTHVVILRAEG-RGFNAGVDikemQNTEGFTALIDANR----GCY 84
Cdd:PRK07396  22 GIAKITINRPEVrNAFRPKTVKEMIDAFADARDDDNIGVIILTGAGdKAFCSGGD----QKVRGYGGYVDDDGvprlNVL 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  85 EAFRAVYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGL--PEVER--GALGAAtHLSRLVPQHMMRRLFFTAA 160
Cdd:PRK07396  98 DLQRLIRTCPKPVIAMVAGYAIGGGHVLHLVCDLTIAADNAIFGQtgPKVGSfdGGYGAS-YLARIVGQKKAREIWFLCR 176

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 490023884 161 TVDAHTLHHFGSVHEVVPRAELDEAALRVARDIAAKDTRVIRAAKEALN 209
Cdd:PRK07396 177 QYDAQEALDMGLVNTVVPLADLEKETVRWCREMLQNSPMALRCLKAALN 225
PRK07854 PRK07854
enoyl-CoA hydratase; Provisional
 6-209 1.35e-15

enoyl-CoA hydratase; Provisional


Pssm-ID: 236115 [Multi-domain]  Cd Length: 243  Bit Score: 73.52  E-value: 1.35e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   6 TSPEPGIVSVTVDYPPV-NAIPSRGWFELADAITAAGrDQQTHVVILRAEGRGFNAGVDIKEMQNTEGFT-ALIDANRgc 83
Cdd:PRK07854   4 VTRDGQVLTIELQRPERrNALNAELCEELREAVRKAV-DESARAIVLTGQGTVFCAGADLSGDVYADDFPdALIEMLH-- 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  84 yeafrAVYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERG-ALGAATH--LSRLVPQHMMRRLFFTAA 160
Cdd:PRK07854  81 -----AIDAAPVPVIAAINGPAIGAGLQLAMACDLRVVAPEAYFQFPVAKYGiALDNWTIrrLSSLVGGGRARAMLLGAE 155

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 490023884 161 TVDAHTLHHFGSVHEVVPRAEldeaALRVARDIAAKDTRVIRAAKEALN 209
Cdd:PRK07854 156 KLTAEQALATGMANRIGTLAD----AQAWAAEIAGLAPLALQHAKRVLN 200
PRK12478 PRK12478
crotonase/enoyl-CoA hydratase family protein;
12-237 2.94e-15

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 183548  Cd Length: 298  Bit Score: 73.45  E-value: 2.94e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  12 IVSVTVDYPP-VNAIPSRGWFELADAITAAGRDQQTHVVILRAEGRGFNAGVDI-------KEMQNTEG-------FTAL 76
Cdd:PRK12478  15 VATITLNRPEqLNTIVPPMPDEIEAAIGLAERDQDIKVIVLRGAGRAFSGGYDFgggfqhwGEAMMTDGrwdpgkdFAMV 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  77 IDANRGCYEAFRAVYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVER-GALGAATHLSRL----VPQHM 151
Cdd:PRK12478  95 TARETGPTQKFMAIWRASKPVIAQVHGWCVGGASDYALCADIVIASDDAVIGTPYSRMwGAYLTGMWLYRLslakVKWHS 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884 152 MRRLFFTAATVDAHTLhhfgsVHEVVPRAELDEaalRVArDIAAKDTRVIRAAKEALNFIdvqrVNSSYRmEQGFTFELN 231
Cdd:PRK12478 175 LTGRPLTGVQAAEAEL-----INEAVPFERLEA---RVA-EVATELARIPLSQLQAQKLI----VNQAYE-NMGLASTQT 240


                 ....*.
gi 490023884 232 LAGVAD 237
Cdd:PRK12478 241 LGGILD 246
PRK05980 PRK05980
crotonase/enoyl-CoA hydratase family protein;
11-209 6.14e-15

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180335 [Multi-domain]  Cd Length: 260  Bit Score: 72.10  E-value: 6.14e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  11 GIVSVTVDYPP-VNAIPSRGWFELADAITAAGRDQQTHVVILRAEG-RGFNAGVDIKEMQNTEGF---TALID-ANRGC- 83
Cdd:PRK05980  12 GIALLTLNRPEkLNALNYALIDRLLARLDAIEVDESVRAVILTGAGdRAFSAGADIHEFSASVAAgadVALRDfVRRGQa 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  84 ----YEAFRAvyecavPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERG---ALGAATHLSRLVPQHMMRRLF 156
Cdd:PRK05980  92 mtarLEAFPK------PVIAAVNGLAFGGGCEITEAVHLAIASERALFAKPEIRLGmppTFGGTQRLPRLAGRKRALELL 165

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 490023884 157 FTAATVDAHTLHHFGSVHEVVPRAELDEAALRVARDIAAKD----TRVIRAAKEALN 209
Cdd:PRK05980 166 LTGDAFSAERALEIGLVNAVVPHEELLPAARALARRIIRHSpvavAAILTAVTRGLN 222
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
 32-209 7.08e-14

enoyl-CoA hydratase; Provisional


Pssm-ID: 236163  Cd Length: 262  Bit Score: 69.17  E-value: 7.08e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  32 ELADAITAAgRDQQTHVVILRAEGRGFNAGVDIKEMQNTEG-----FTALIDANrgcYEAF-RAVYECAVPVVAAVNGFC 105
Cdd:PRK08140  35 ELREALDQV-EDDGARALLLTGAGRGFCAGQDLADRDVTPGgampdLGESIETF---YNPLvRRLRALPLPVIAAVNGVA 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884 106 VGGGIGLVGNSDVIVASDDAKF-------GL-PEVergalGAATHLSRLVPQHMMRRLFFTAATVDAHTLHHFGSVHEVV 177
Cdd:PRK08140 111 AGAGANLALACDIVLAARSASFiqafvkiGLvPDS-----GGTWFLPRLVGMARALGLALLGEKLSAEQAEQWGLIWRVV 185

                        170       180       190
                 ....*....|....*....|....*....|..
gi 490023884 178 PRAELDEAALRVARDIAAKDTRVIRAAKEALN 209
Cdd:PRK08140 186 DDAALADEAQQLAAHLATQPTRGLALIKQAMN 217
PRK05864 PRK05864
enoyl-CoA hydratase; Provisional
 8-195 1.98e-13

enoyl-CoA hydratase; Provisional


Pssm-ID: 168278 [Multi-domain]  Cd Length: 276  Bit Score: 68.32  E-value: 1.98e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   8 PEPGIVSVTVDYPP-VNAIPSRGWFELADAITAAGRDQQTHVVILRAEGRGFNAGVDIKE---MQNTEGFTALIDANRGC 83
Cdd:PRK05864  16 PRPEIALITLNRPErMNSMAFDVMVPLKEALAEVSYDNSVRVVVLTGAGRGFSSGADHKSagvVPHVEGLTRPTYALRSM 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  84 Y---EAFRAVYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERGALGAATHLSRLVPQHM-MRRLF--- 156
Cdd:PRK05864  96 ElldDVILALRRLHQPVIAAVNGPAIGGGLCLALAADIRVASSSAYFRAAGINNGLTASELGLSYLLPRAIgSSRAFeim 175

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 490023884 157 FTAATVDAHTLHHFGSVHEVVPRAELDEAALRVARDIAA 195
Cdd:PRK05864 176 LTGRDVDAEEAERIGLVSRQVPDEQLLDTCYAIAARMAG 214
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 32-209 4.77e-13

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 67.49  E-value: 4.77e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   32 ELADAITAAGRDQQTHVVILRAEG-RGFNAGVDIKEMQNTegftALIDANRGCYEAFRAVYE-------CAVPVVAAVNG 103
Cdd:pfam16113  22 ALLAALKAWEDDPAVKLVVLKGAGeRAFCAGGDVRALYEA----AKAGGGEAGRDFFREEYRlnyliatYPKPYVALMDG 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  104 FCVGGGIGLVGNSDVIVASDDAKFGLPEVergALG-----AATH-LSRLvPQHMMRRLFFTAATVDAHTLHHFGSVHEVV 177
Cdd:pfam16113  98 IVMGGGVGLSVHGSFRVVTERTRFAMPET---AIGlfpdvGGSYfLSRL-PGELGLYLALTGARLNGADALAAGLATHYV 173

                         170       180       190
                  ....*....|....*....|....*....|..
gi 490023884  178 PRAELDEaalrVARDIAAKDTRVIRAAKEALN 209
Cdd:pfam16113 174 PSARLPA----LEEALAALDWSDPADVDAVLA 201
PRK07110 PRK07110
polyketide biosynthesis enoyl-CoA hydratase; Validated
 3-208 6.58e-13

polyketide biosynthesis enoyl-CoA hydratase; Validated


Pssm-ID: 235936  Cd Length: 249  Bit Score: 66.14  E-value: 6.58e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   3 ITTTSPEPGIVSVTVDYPP-VNAIPSRGWFELADAITAAGRDQQTHVVILRAEGRGFNAGVDIKEMQN-TEGFTALIDAN 80
Cdd:PRK07110   6 VELREVEEGIAQVTMQDRVnKNAFSDELCDQLHEAFDTIAQDPRYKVVILTGYPNYFATGGTQEGLLSlQTGKGTFTEAN 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  81 rgcyeAFRAVYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDD-------AKFGL-PEvergaLGAATHLSRLVPQHMM 152
Cdd:PRK07110  86 -----LYSLALNCPIPVIAAMQGHAIGGGLVLGLYADIVVLSREsvytanfMKYGFtPG-----MGATAILPEKLGLALG 155

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 490023884 153 RRLFFTAATVDAHTLHHFGSVHEVVPRAELDEAALRVARDIAAKDTRVIRAAKEAL 208
Cdd:PRK07110 156 QEMLLTARYYRGAELKKRGVPFPVLPRAEVLEKALELARSLAEKPRHSLVLLKDHL 211
PRK09076 PRK09076
enoyl-CoA hydratase; Provisional
 15-206 8.56e-13

enoyl-CoA hydratase; Provisional


Pssm-ID: 236373 [Multi-domain]  Cd Length: 258  Bit Score: 66.10  E-value: 8.56e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  15 VTVDYPPVNAIPSRGWFELADAITAAGRDQQTHVVILRAEG-RGFNAGVDIKemQNTEGFTAL-IDANRGCYEAFRAVYE 92
Cdd:PRK09076  16 LTLNNPPANTWTADSLQALKQLVLELNADKDVYALVITGDGeKFFSAGADLN--LFADGDKAVaREMARRFGEAFEALSA 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  93 CAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERGAL---GAATHLSRLVPQHMMRRLFFTAATVDAHTLHH 169
Cdd:PRK09076  94 FRGVSIAAINGYAMGGGLECALACDIRIAEEQAQMALPEASVGLLpcaGGTQNLPWLVGEGWAKRMILCGERVDAATALR 173

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 490023884 170 FGSVHEVVPRAELDEAALRVARDIAAKDTRVIRAAKE 206
Cdd:PRK09076 174 IGLVEEVVEKGEAREAALALAQKVANQSPSAVAACKT 210
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
48-205 4.15e-12

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 65.30  E-value: 4.15e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  48 VVILRAEGRGFNAGVDIKEMQNTEGFTALIDANRGCYEAFRAVYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAK- 126
Cdd:PRK11154  55 VVFISGKPDNFIAGADINMLAACKTAQEAEALARQGQQLFAEIEALPIPVVAAIHGACLGGGLELALACHYRVCTDDPKt 134

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884 127 -FGLPEVERGAL---GAATHLSRLVPQHMMRRLFFTAATVDAHTLHHFGSVHEVVPRAELdeaaLRVARDIAAKDTRVIR 202
Cdd:PRK11154 135 vLGLPEVQLGLLpgsGGTQRLPRLIGVSTALDMILTGKQLRAKQALKLGLVDDVVPHSIL----LEVAVELAKKGKPARR 210


                 ...
gi 490023884 203 AAK 205
Cdd:PRK11154 211 PLP 213
fadB PRK11730
fatty acid oxidation complex subunit alpha FadB;
9-207 4.76e-12

fatty acid oxidation complex subunit alpha FadB;


Pssm-ID: 183293 [Multi-domain]  Cd Length: 715  Bit Score: 65.27  E-value: 4.76e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   9 EPGIVSVTVDYP-PVNAIPSRGWFELADAITAAGRDQQTHVVILRAEGRGFNAGVDIKEmqntegFTALIDA-------- 79
Cdd:PRK11730  14 EDGIAELVFDAPgSVNKLDRATLASLGEALDALEAQSDLKGLLLTSAKDAFIVGADITE------FLSLFAApeeelsqw 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  80 NRGCYEAFRAVYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERG---ALGAATHLSRLVPQHMMRRLF 156
Cdd:PRK11730  88 LHFANSIFNRLEDLPVPTVAAINGYALGGGCECVLATDYRVASPDARIGLPETKLGimpGFGGTVRLPRLIGADNALEWI 167

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 490023884 157 FTAATVDAHTLHHFGSVHEVVPRAELDEAALRVARD-IAAK-DTRVIRAAKEA 207
Cdd:PRK11730 168 AAGKDVRAEDALKVGAVDAVVAPEKLQEAALALLKQaIAGKlDWKARRQPKLE 220
PRK07799 PRK07799
crotonase/enoyl-CoA hydratase family protein;
15-195 8.26e-12

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181122 [Multi-domain]  Cd Length: 263  Bit Score: 63.20  E-value: 8.26e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  15 VTVDYPPV-NAIPSRGWFELADAITAAGRDQQTHVVILRAEGRGFNAGVDIKEM-QNTEGFT---ALIDANRgcYEAFRA 89
Cdd:PRK07799  18 VTMNRPEArNALSTEMLRIMVDAWDRVDNDPDIRSCILTGAGGAFCAGMDLKAAtKKPPGDSfkdGSYDPSR--IDALLK 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  90 VYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERGAL---GAATHLSRLVPQHMMRRLFFTAATVDAHT 166
Cdd:PRK07799  96 GRRLTKPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWSLFpmgGSAVRLVRQIPYTVACDLLLTGRHITAAE 175

                        170       180
                 ....*....|....*....|....*....
gi 490023884 167 LHHFGSVHEVVPRAELDEAALRVARDIAA 195
Cdd:PRK07799 176 AKEIGLIGHVVPDGQALDKALELAELINA 204
PLN02874 PLN02874
3-hydroxyisobutyryl-CoA hydrolase-like protein
 15-214 9.31e-12

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178462 [Multi-domain]  Cd Length: 379  Bit Score: 64.05  E-value: 9.31e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  15 VTVDYPPV-NAIPSRGWFELADAITAAGRDQQTHVVILRAEGRGFNAGVDIKEmqntegFTALIDANRGCYE-AFRAVYE 92
Cdd:PLN02874  24 ITLNRPRQlNVISLSVVSLLAEFLEQWEKDDSVELIIIKGAGRAFSAGGDLKM------FYDGRESDDSCLEvVYRMYWL 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  93 C------AVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERG---ALGAATHLSRLvPQHMMRRLFFTAATVD 163
Cdd:PLN02874  98 CyhihtyKKTQVALVHGLVMGGGAGLMVPMKFRVVTEKTVFATPEASVGfhtDCGFSYILSRL-PGHLGEYLALTGARLN 176

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 490023884 164 AHTLHHFGSVHEVVPRAELDEAALRVArDIAAKDTRVIRAAKEALNfIDVQ 214
Cdd:PLN02874 177 GKEMVACGLATHFVPSEKLPELEKRLL-NLNSGDESAVQEAIEEFS-KDVQ 225
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
 11-202 1.03e-10

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 61.39  E-value: 1.03e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   11 GIVSVTVDYP--PVNAIPSrgwfELADAITAAGRDQQTH-----VVILRAEGRGFNAGVDIKEMQNTEGFTALIDANRGC 83
Cdd:TIGR02441  22 DVAVVKIDSPnsKVNTLSK----ELFAEFKEVMNELWTNeaiksAVLISGKPGSFVAGADIQMIAACKTAQEVTQLSQEG 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   84 YEAFRAVYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAK--FGLPEVERGAL---GAATHLSRLVPQHMMRRLFFT 158
Cdd:TIGR02441  98 QEMFERIEKSQKPIVAAISGSCLGGGLELALACHYRIATKDRKtlLGLPEVMLGLLpgaGGTQRLPKLTGVPAALDMMLT 177

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 490023884  159 AATVDAHTLHHFGSVHEVV--------PRAE-----LDEAALRVARDIAAKDTRVIR 202
Cdd:TIGR02441 178 GKKIRADRAKKMGIVDQLVdplgpglkPAEEntieyLEEVAVKFAQGLANGKLSINR 234
PLN03214 PLN03214
probable enoyl-CoA hydratase/isomerase; Provisional
 11-208 1.43e-10

probable enoyl-CoA hydratase/isomerase; Provisional


Pssm-ID: 215635  Cd Length: 278  Bit Score: 59.89  E-value: 1.43e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  11 GIVSVTVDYPPVNAIPSRGWFELADAITAAGRDQQTHVVILRAEGRG--FNAGVDIKEMQNTEGFTALIDANRGCYEAFR 88
Cdd:PLN03214  21 GIAVVWLAKEPVNSMTLAMWRSLDDALTALENDPTVRGVVFASGLRRdvFTAGNDIAELYAPKTSAARYAEFWLTQTTFL 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  89 A-VYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVergALGAAthlsrlVPQHMMRRLFFTA-------- 159
Cdd:PLN03214 101 VrLLRSRLATVCAIRGACPAGGCAVSLCCDYRLQTTEGTMGLNEV---ALGIP------VPKFWARLFMGRVidrkvaes 171

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 490023884 160 -----ATVDAHTLHHFGSVHEVVPRAELDEAALRVARDiAAKDTRVIRAAKEAL 208
Cdd:PLN03214 172 lllrgRLVRPAEAKQLGLIDEVVPAAALMEAAASAMER-ALKLPSAARAATKAL 224
PRK06072 PRK06072
enoyl-CoA hydratase; Provisional
 11-211 1.99e-09

enoyl-CoA hydratase; Provisional


Pssm-ID: 168377 [Multi-domain]  Cd Length: 248  Bit Score: 56.33  E-value: 1.99e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  11 GIVSVTVDYP-PVNAIPSRGWFELADAITAAGRDQQTHVVILRAEGRGFNAGVDIKEMqnTEGFTalIDANRGCYEAFRA 89
Cdd:PRK06072   9 GYAIVTMSRPdKLNALNLEMRNEFISKLKQINADPKIRVVIVTGEGRAFCVGADLSEF--APDFA--IDLRETFYPIIRE 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  90 VYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFgLPEVERGAL----GAATHLSRLVPQHMMRRLfFTAATVDAH 165
Cdd:PRK06072  85 IRFSDKIYISAINGVTAGACIGIALSTDFKFASRDVKF-VTAFQRLGLasdtGVAYFLLKLTGQRFYEIL-VLGGEFTAE 162

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 490023884 166 TLHHFGSVhEVV--PRAEldeaALRVARDIAAKDTRVIRAAKEALNFI 211
Cdd:PRK06072 163 EAERWGLL-KISedPLSD----AEEMANRISNGPFQSYIAAKRMINLV 205
PRK05981 PRK05981
enoyl-CoA hydratase/isomerase;
5-198 2.06e-09

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235661  Cd Length: 266  Bit Score: 56.67  E-value: 2.06e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   5 TTSPEPGIVSVTVDYPPV-NAIPSRGWFELADAITA-AGRDQQTHVVILRAEGRGFNAGVDIKEMQN-TEGFTALIDANR 81
Cdd:PRK05981   7 TLDFDGGVAILTLDHPEVmNAVSIDMLGGLAEALDAiEDGKAEVRCLVLTGAGRGFCTGANLQGRGSgGRESDSGGDAGA 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  82 GCYEAF----RAVYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFgLPEVERGAL----GAATHLSRLVPQHMMR 153
Cdd:PRK05981  87 ALETAYhpflRRLRNLPCPIVTAVNGPAAGVGMSFALMGDLILCARSAYF-LQAFRRIGLvpdgGSTWLLPRLVGKARAM 165

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 490023884 154 RLFFTAATVDAHTLHHFGSVHEVVPRAELDEAALRVARDIAAKDT 198
Cdd:PRK05981 166 ELSLLGEKLPAETALQWGLVNRVVDDAELMAEAMKLAHELANGPT 210
PRK06213 PRK06213
crotonase/enoyl-CoA hydratase family protein;
5-212 4.17e-09

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235744  Cd Length: 229  Bit Score: 55.37  E-value: 4.17e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   5 TTSPEPGIVSVTVDYPPVNAIPSRGWFELADAITAAGRDQQthVVILRAEGRGFNAGVDIKEMqnTEGFTALIDANRGCY 84
Cdd:PRK06213   6 SYTLEDGVATITLDDGKVNALSPAMIDALNAALDQAEDDRA--VVVITGQPGIFSGGFDLKVM--TSGAQAAIALLTAGS 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  85 EAFRAVYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASD-DAKFGLPEVergALG-----AATHLSRL-VPQHMMRRLFF 157
Cdd:PRK06213  82 TLARRLLSHPKPVIVACTGHAIAKGAFLLLSADYRIGVHgPFKIGLNEV---AIGmtmphAAIELARDrLTPSAFQRAVI 158

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 490023884 158 TAATVDAHTLHHFGSVHEVVPRAELDEAALRVARDIAA------KDTRvIRAAKEALNFID 212
Cdd:PRK06213 159 NAEMFDPEEAVAAGFLDEVVPPEQLLARAQAAARELAGlnmgahAATK-LKVRAAALEAIR 218
PRK07659 PRK07659
enoyl-CoA hydratase; Provisional
 32-186 1.26e-07

enoyl-CoA hydratase; Provisional


Pssm-ID: 236073 [Multi-domain]  Cd Length: 260  Bit Score: 51.19  E-value: 1.26e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  32 ELADAITAAgRDQQTHVVILRAEGRGFNAGVDIKEM---QNTEGFTALIDAnrgCYEAFRAVYECAVPVVAAVNGFCVGG 108
Cdd:PRK07659  37 ELLQALKEV-AESSAHIVVLRGNGRGFSAGGDIKMMlssNDESKFDGVMNT---ISEIVVTLYTMPKLTISAIHGPAAGL 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884 109 GIGLVGNSDVIVASDDAKF-----GLPEVERGalGAATHLSRLVPQHMMRRLFFTAATVDAHTLHHFGSVHEVVpRAELD 183
Cdd:PRK07659 113 GLSIALTADYVIADISAKLamnfiGIGLIPDG--GGHFFLQKRVGENKAKQIIWEGKKLSATEALDLGLIDEVI-GGDFQ 189


                 ...
gi 490023884 184 EAA 186
Cdd:PRK07659 190 TAA 192
PRK08259 PRK08259
crotonase/enoyl-CoA hydratase family protein;
32-195 2.75e-07

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236205  Cd Length: 254  Bit Score: 50.28  E-value: 2.75e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  32 ELADAITAAGRDQQTHVVILRAEGRGFNAGVDIKEMQNTEGfTALIDANRGCYEAFRAVYecAVPVVAAVNGFCVGGGIG 111
Cdd:PRK08259  34 ALADAFRAFDADDAASVAVLWGAGGTFCAGADLKAVGTGRG-NRLHPSGDGPMGPSRMRL--SKPVIAAVSGYAVAGGLE 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884 112 LVGNSDVIVASDDA-------KFGLPEVErgalGAATHLSRLVPQHMMRRLFFTAATVDAHTLHHFGSVHEVVPRAELDE 184
Cdd:PRK08259 111 LALWCDLRVAEEDAvfgvfcrRWGVPLID----GGTVRLPRLIGHSRAMDLILTGRPVDADEALAIGLANRVVPKGQARA 186

                        170
                 ....*....|.
gi 490023884 185 AALRVARDIAA 195
Cdd:PRK08259 187 AAEELAAELAA 197
PRK06023 PRK06023
crotonase/enoyl-CoA hydratase family protein;
10-206 1.31e-06

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 168351  Cd Length: 251  Bit Score: 48.25  E-value: 1.31e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  10 PGIVSVTVDYP-PVNAIPSRGWFELADAITAAGRDQQTHVVILRAEGRGFNAGVDIKE-----MQNTEGFTALIDAnrgc 83
Cdd:PRK06023  14 PGVQVIRFNRPeKKNAITRAMYATMAKALKAADADDAIRAHVFLGTEGCFSAGNDMQDflaaaMGGTSFGSEILDF---- 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  84 yeaFRAVYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERGALGAATHlSRLVPQHM-MRRLFFTAAT- 161
Cdd:PRK06023  90 ---LIALAEAEKPIVSGVDGLAIGIGTTIHLHCDLTFASPRSLFRTPFVDLALVPEAGS-SLLAPRLMgHQRAFALLALg 165

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 490023884 162 --VDAHTLHHFGSVHEVVPRAELDEAALRVARDIAAKDTRVIRAAKE 206
Cdd:PRK06023 166 egFSAEAAQEAGLIWKIVDEEAVEAETLKAAEELAAKPPQALQIARD 212
PRK07260 PRK07260
enoyl-CoA hydratase; Provisional
 32-127 4.86e-06

enoyl-CoA hydratase; Provisional


Pssm-ID: 180910 [Multi-domain]  Cd Length: 255  Bit Score: 46.27  E-value: 4.86e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  32 ELADAITAAGRDQQTHVVILRAEGRGFNAGVDIKEMQ---NTEGFTALIDANRGCYEAFRAVYECAVPVVAAVNGFCVGG 108
Cdd:PRK07260  33 EILEALRLAEEDPSVRFLLINANGKVFSVGGDLVEMKravDEDDVQSLVKIAELVNEISFAIKQLPKPVIMCVDGAVAGA 112

                         90
                 ....*....|....*....
gi 490023884 109 GIGLVGNSDVIVASDDAKF 127
Cdd:PRK07260 113 AANMAVAADFCIASTKTKF 131
PRK08788 PRK08788
enoyl-CoA hydratase; Validated
 98-188 2.77e-05

enoyl-CoA hydratase; Validated


Pssm-ID: 236338  Cd Length: 287  Bit Score: 44.52  E-value: 2.77e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  98 VAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERG---ALGAATHLSRLVPQHMMRRLFFTAATVDAHTLHHFGSVH 174
Cdd:PRK08788 125 IALVQGDALGGGFEAALSHHTIIAERGAKMGFPEILFNlfpGMGAYSFLARRVGPKLAEELILSGKLYTAEELHDMGLVD 204

                         90
                 ....*....|....
gi 490023884 175 EVVPRAElDEAALR 188
Cdd:PRK08788 205 VLVEDGQ-GEAAVR 217
PLN02988 PLN02988
3-hydroxyisobutyryl-CoA hydrolase
 15-182 2.94e-05

3-hydroxyisobutyryl-CoA hydrolase


Pssm-ID: 178568 [Multi-domain]  Cd Length: 381  Bit Score: 44.71  E-value: 2.94e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  15 VTVDYPP-VNAIPSRGWFELADAITAAGRDQQTHVVILRAEGRGFNAGVDIKEM-QNTEGFTALIDANRGCYEAF----R 88
Cdd:PLN02988  22 LTLNRPKqLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAVvRDIEQGNWRLGANFFSDEYMlnyvM 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  89 AVYECAVpvVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERGA---LGAATHLSRLvPQHMMRRLFFTAATVDAH 165
Cdd:PLN02988 102 ATYSKAQ--VSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLfpdVGASYFLSRL-PGFFGEYVGLTGARLDGA 178

                        170
                 ....*....|....*..
gi 490023884 166 TLHHFGSVHEVVPRAEL 182
Cdd:PLN02988 179 EMLACGLATHFVPSTRL 195
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
 32-208 5.22e-05

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 43.66  E-value: 5.22e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  32 ELADAITAA----GRDQQTHVVILRAEG-RGFNAGVDIKEMQN--TEGFTALIDAN-RGCYEAFRAVYECAVPVVAAVNG 103
Cdd:PRK05617  30 EMIRAIDAAldawEDDDAVAAVVIEGAGeRGFCAGGDIRALYEaaRAGDPLAADRFfREEYRLNALIARYPKPYIALMDG 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884 104 FCVGGGIGLVGNSDVIVASDDAKFGLPEVERG---ALGAATHLSRLvPQHMMRRLFFTAATVDAHTLHHFGSVHEVVPRA 180
Cdd:PRK05617 110 IVMGGGVGISAHGSHRIVTERTKMAMPETGIGffpDVGGTYFLSRA-PGALGTYLALTGARISAADALYAGLADHFVPSA 188

                        170       180
                 ....*....|....*....|....*...
gi 490023884 181 ELDEAALRVARDIAAKDTRVIRAAKEAL 208
Cdd:PRK05617 189 DLPALLDALISLRWDSGADVVDAALAAF 216
PLN02157 PLN02157
3-hydroxyisobutyryl-CoA hydrolase-like protein
 20-146 3.57e-04

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 177817 [Multi-domain]  Cd Length: 401  Bit Score: 41.21  E-value: 3.57e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  20 PPVNAIPSRGWFELADAITAAGRDQQTHVVILRAEGRGFNAGVDIKEMQNTEgftalidaNRGCYEAFRAVYECAV---- 95
Cdd:PLN02157  56 PALNALTTHMGYRLQKLYKNWEEDPNIGFVMMKGSGRAFCAGGDIVSLYHLR--------KRGSPDAIREFFSSLYsfiy 127

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 490023884  96 -------PVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERG---ALGAATHLSRL 146
Cdd:PLN02157 128 llgtylkPHVAILNGVTMGGGTGVSIPGTFRVATDRTIFATPETIIGfhpDAGASFNLSHL 188
PRK07112 PRK07112
enoyl-CoA hydratase/isomerase;
9-182 8.04e-04

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235938  Cd Length: 255  Bit Score: 39.67  E-value: 8.04e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884   9 EPGIVSVTVDYPPV-NAIPSRGWFELADAITAAGRDqqTHVVILRAEGRGFNAGVDIKEM--QNTEGFTALIDANRgCYE 85
Cdd:PRK07112  11 QGDVCFLQLHRPEAqNTINDRLIAECMDVLDRCEHA--ATIVVLEGLPEVFCFGADFSAIaeKPDAGRADLIDAEP-LYD 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490023884  86 AFRAVYECAVPVVAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERGALGAAT--HLSRLVPQHMMRRLFFTAATVD 163
Cdd:PRK07112  88 LWHRLATGPYVTIAHVRGKVNAGGIGFVAASDIVIADETAPFSLSELLFGLIPACVlpFLIRRIGTQKAHYMTLMTQPVT 167

                        170
                 ....*....|....*....
gi 490023884 164 AHTLHHFGSVHEVVPRAEL 182
Cdd:PRK07112 168 AQQAFSWGLVDAYGANSDT 186
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH