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Conserved domains on  [gi|489336608|ref|WP_003243824|]
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MULTISPECIES: peptidyl-prolyl cis-trans isomerase [Bacillus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
prsA super family cl35053
peptidylprolyl isomerase; Provisional
 10-285 1.58e-35

peptidylprolyl isomerase; Provisional


The actual alignment was detected with superfamily member PRK00059:

Pssm-ID: 234605 [Multi-domain]  Cd Length: 336  Bit Score: 130.60  E-value: 1.58e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489336608  10 ILGALLVCCIAVAYT----LTKSQAGASSSgeSIATIGGKSVTREE---------WLKEMEDQYG--------------- 61
Cdd:PRK00059   7 LVASLLVGVFIFSAVgcnmIEKTPEAIAKS--TVATVNGEKITRGDldkdpkmqqVLEQLKQQYGdnyekneqvkeqikq 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489336608  62 --KSTLEDMINVRVVEQLAKKNKLKIS----KSEVDREFLLIKAVNN-------SFYEDEHTTEKEWKDQIRYNILLEDL 128
Cdd:PRK00059  85 qkEQILDSLITEKVLLQKAKELKLIPSeeelNKEVDKKINEIKKQFNndeeqfeEALKATGFTEETFKEYLKNQIIIEKV 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489336608 129 ---LTRDIDISNKELESFYNKNKELY-QFDDSYRIRHIVVKDEEEAREVLKELKGGSSFEAVAAERSTDRYTSPYGGDLG 204
Cdd:PRK00059 165 ineVVKDVKVTDKDAQKYYNENKSKFtEKPNTMHLAHILVKTEDEAKKVKKRLDKGEDFAKVAKEVSQDPGSKDKGGDLG 244

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489336608 205 FVTEASDNIPSAYIEEAKTLKEDEWSQePIKVSNGYAIIQLKEKLKARTFSFDEVKDQIRRQIAMDQLGDKATVK-TLWK 283
Cdd:PRK00059 245 DVPYSDSGYDKEFMDGAKALKEGEISA-PVKTQFGYHIIKAIKKKEYPVKPFDSVKEDIKKQLLQEKQSEVFKKKiEEWK 323


                 ..
gi 489336608 284 EA 285
Cdd:PRK00059 324 KA 325
 
Name Accession Description Interval E-value
prsA PRK00059
peptidylprolyl isomerase; Provisional
 10-285 1.58e-35

peptidylprolyl isomerase; Provisional


Pssm-ID: 234605 [Multi-domain]  Cd Length: 336  Bit Score: 130.60  E-value: 1.58e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489336608  10 ILGALLVCCIAVAYT----LTKSQAGASSSgeSIATIGGKSVTREE---------WLKEMEDQYG--------------- 61
Cdd:PRK00059   7 LVASLLVGVFIFSAVgcnmIEKTPEAIAKS--TVATVNGEKITRGDldkdpkmqqVLEQLKQQYGdnyekneqvkeqikq 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489336608  62 --KSTLEDMINVRVVEQLAKKNKLKIS----KSEVDREFLLIKAVNN-------SFYEDEHTTEKEWKDQIRYNILLEDL 128
Cdd:PRK00059  85 qkEQILDSLITEKVLLQKAKELKLIPSeeelNKEVDKKINEIKKQFNndeeqfeEALKATGFTEETFKEYLKNQIIIEKV 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489336608 129 ---LTRDIDISNKELESFYNKNKELY-QFDDSYRIRHIVVKDEEEAREVLKELKGGSSFEAVAAERSTDRYTSPYGGDLG 204
Cdd:PRK00059 165 ineVVKDVKVTDKDAQKYYNENKSKFtEKPNTMHLAHILVKTEDEAKKVKKRLDKGEDFAKVAKEVSQDPGSKDKGGDLG 244

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489336608 205 FVTEASDNIPSAYIEEAKTLKEDEWSQePIKVSNGYAIIQLKEKLKARTFSFDEVKDQIRRQIAMDQLGDKATVK-TLWK 283
Cdd:PRK00059 245 DVPYSDSGYDKEFMDGAKALKEGEISA-PVKTQFGYHIIKAIKKKEYPVKPFDSVKEDIKKQLLQEKQSEVFKKKiEEWK 323


                 ..
gi 489336608 284 EA 285
Cdd:PRK00059 324 KA 325
SurA COG0760
Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, ...
 151-287 1.36e-28

Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440523 [Multi-domain]  Cd Length: 143  Bit Score: 106.97  E-value: 1.36e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489336608 151 YQFDDSYRIRHIVV---------KDEEEAREVLKELKGGSSFEAVAAERSTDRYTSPYGGDLGFVTEasDNIPSAYIEEA 221
Cdd:COG0760    3 FDSPEEVRASHILVkvppsedraKAEAKAEELLAQLKAGADFAELAKEYSQDPGSAANGGDLGWFSR--GQLVPEFEEAA 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489336608 222 KTLKEDEWSqEPIKVSNGYAIIQLKEKLKARTFSFDEVKDQIRRQIAMDQLgdKATVKTLWKEADV 287
Cdd:COG0760   81 FALKPGEIS-GPVKTQFGYHIIKVEDRRPAETPPFEEVKQQIRQELFQQAL--EAWLEELRKKAKI 143
Rotamase_2 pfam13145
PPIC-type PPIASE domain;
135-261 5.77e-20

PPIC-type PPIASE domain;


Pssm-ID: 432992 [Multi-domain]  Cd Length: 121  Bit Score: 83.26  E-value: 5.77e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489336608  135 ISNKELESFYNKNKELYQFDDSYRIRHIVVKDEEEAREVLKELKGGSSFEAVAAERSTDRYTSPYGgdlgfVTEASDNIP 214
Cdd:pfam13145   1 VTEEELKAYYEENKDEFSTPEGRLLEILVFKDQVAADAALALLKAGALEDFAALAKGEGIKAATLD-----IVESAELLP 75

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 489336608  215 SAYIEEAKTLKEDEWSqEPIKVSNGYAIIQLKEKLKARTFSFDEVKD 261
Cdd:pfam13145  76 EELAKAAFALKPGEVS-GPIKTGNGYYVVRVTEIKPAQPLPFEEAKD 121
 
Name Accession Description Interval E-value
prsA PRK00059
peptidylprolyl isomerase; Provisional
 10-285 1.58e-35

peptidylprolyl isomerase; Provisional


Pssm-ID: 234605 [Multi-domain]  Cd Length: 336  Bit Score: 130.60  E-value: 1.58e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489336608  10 ILGALLVCCIAVAYT----LTKSQAGASSSgeSIATIGGKSVTREE---------WLKEMEDQYG--------------- 61
Cdd:PRK00059   7 LVASLLVGVFIFSAVgcnmIEKTPEAIAKS--TVATVNGEKITRGDldkdpkmqqVLEQLKQQYGdnyekneqvkeqikq 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489336608  62 --KSTLEDMINVRVVEQLAKKNKLKIS----KSEVDREFLLIKAVNN-------SFYEDEHTTEKEWKDQIRYNILLEDL 128
Cdd:PRK00059  85 qkEQILDSLITEKVLLQKAKELKLIPSeeelNKEVDKKINEIKKQFNndeeqfeEALKATGFTEETFKEYLKNQIIIEKV 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489336608 129 ---LTRDIDISNKELESFYNKNKELY-QFDDSYRIRHIVVKDEEEAREVLKELKGGSSFEAVAAERSTDRYTSPYGGDLG 204
Cdd:PRK00059 165 ineVVKDVKVTDKDAQKYYNENKSKFtEKPNTMHLAHILVKTEDEAKKVKKRLDKGEDFAKVAKEVSQDPGSKDKGGDLG 244

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489336608 205 FVTEASDNIPSAYIEEAKTLKEDEWSQePIKVSNGYAIIQLKEKLKARTFSFDEVKDQIRRQIAMDQLGDKATVK-TLWK 283
Cdd:PRK00059 245 DVPYSDSGYDKEFMDGAKALKEGEISA-PVKTQFGYHIIKAIKKKEYPVKPFDSVKEDIKKQLLQEKQSEVFKKKiEEWK 323


                 ..
gi 489336608 284 EA 285
Cdd:PRK00059 324 KA 325
prsA PRK04405
peptidylprolyl isomerase; Provisional
 12-288 2.66e-31

peptidylprolyl isomerase; Provisional


Pssm-ID: 235295 [Multi-domain]  Cd Length: 298  Bit Score: 118.35  E-value: 2.66e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489336608  12 GALLVCCIAVAYTLtksqAGASSSGESIATIGGKSVTREEWLKEMED-QYGKSTLEDMINVRVVEQLAKKnklKISKSEV 90
Cdd:PRK04405   8 WALAAASAGLALSL----AGCSSNQATVATYSGGKITQSQYYKEMKQsSAGKTVLANMIIYRALEKQYGK---KVSTKKV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489336608  91 DREFLLIK----AVNNSFYEDEHTTEKEWKDQIRYNILLEDLLTRDIDISNKELEsfynknKELYQFDDSYRIRHIVVKD 166
Cdd:PRK04405  81 DKQYNSYKkqygSSFDSVLSQNGMTTSSFKQNLRTNLLSEAALKKLKKVTNSQLK------KAWKSYQPKVTVQHILVSK 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489336608 167 EEEAREVLKELKGGSSFEAVAAERSTDRYTSPYGGDLGFVTEASDNIPSAYIEEAKTLKEDEWSQEPIKVSNGYAIIQLK 246
Cdd:PRK04405 155 KSTAETVIKKLKDGKDFAKLAKKYSTDTATKNKGGKLSAFDSTDTTLDSTFKTAAFKLKNGEYTTTPVKTTYGYEVIKMI 234

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 489336608 247 EKLKARTFS--FDEVKDQIRRQIAMDQLGDKATVKTLWKEADVS 288
Cdd:PRK04405 235 KHPAKGTFSdhKKALTKQIYAKWASDSSVMQRVISKVLKKANVS 278
SurA COG0760
Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, ...
 151-287 1.36e-28

Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440523 [Multi-domain]  Cd Length: 143  Bit Score: 106.97  E-value: 1.36e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489336608 151 YQFDDSYRIRHIVV---------KDEEEAREVLKELKGGSSFEAVAAERSTDRYTSPYGGDLGFVTEasDNIPSAYIEEA 221
Cdd:COG0760    3 FDSPEEVRASHILVkvppsedraKAEAKAEELLAQLKAGADFAELAKEYSQDPGSAANGGDLGWFSR--GQLVPEFEEAA 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489336608 222 KTLKEDEWSqEPIKVSNGYAIIQLKEKLKARTFSFDEVKDQIRRQIAMDQLgdKATVKTLWKEADV 287
Cdd:COG0760   81 FALKPGEIS-GPVKTQFGYHIIKVEDRRPAETPPFEEVKQQIRQELFQQAL--EAWLEELRKKAKI 143
prsA PRK03002
peptidylprolyl isomerase PrsA;
20-284 8.04e-26

peptidylprolyl isomerase PrsA;


Pssm-ID: 101162 [Multi-domain]  Cd Length: 285  Bit Score: 103.48  E-value: 8.04e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489336608  20 AVAYTLTKSQAGASSSGESIATIGGKSVTREEWLKEMEDQYGKSTLEDMINVRVVEQlakknKLKISKSEVDREFLLIKA 99
Cdd:PRK03002  11 ALISILMLSACGQKNSSATVATATDSTITKSDFEKQLKDRYGKDMLYEMMAQDVITK-----KYKVSDDDVDKEVQKAKS 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489336608 100 -----VNNSFYEDEHTTEKEWKDQIRYNILLEDLLTRDIdiSNKELESFYNKnkelyqfddSYRIRHIVVKDEEEAREVL 174
Cdd:PRK03002  86 qygdqFKNVLKNNGLKDEADFKNQIKFKLAMNEAIKKSV--TEKDVKDHYKP---------EIKASHILVSDENEAKEIK 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489336608 175 KELKGGSSFEAVAAERSTDRYTSPYGGDLGFVteASDNIPSAYIEEAKTLKEDEWSqEPIKVSNGYAIIQLKEKLKARtf 254
Cdd:PRK03002 155 KKLDAGASFEELAKQESQDLLSKEKGGDLGYF--NSGRMAPEFETAAYKLKVGQIS-NPVKSPNGYHIIKLTDKKDLK-- 229

                        250       260       270
                 ....*....|....*....|....*....|
gi 489336608 255 SFDEVKDQIRRQIAMDQLGDKATVKTLWKE 284
Cdd:PRK03002 230 PYDEVKDSIRKNLEEERTADPIFGKKLLQS 259
prsA PRK03095
peptidylprolyl isomerase PrsA;
30-287 2.68e-23

peptidylprolyl isomerase PrsA;


Pssm-ID: 179537 [Multi-domain]  Cd Length: 287  Bit Score: 96.60  E-value: 2.68e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489336608  30 AGASSSGESIATIGGKSVTREEWLKEMEDQYGKSTLEDMinvrVVEQLAKKNkLKISKSEVDREF-LLIKAVNNSF---Y 105
Cdd:PRK03095  18 ACGTSSSDKIVTSKAGDITKDEFYEQMKTQAGKQVLNNM----VMEKVLIKN-YKVEDKEVDKKYdEMKKQYGDQFdtlL 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489336608 106 EDEHTTEKEWKDQIRYNILLEDLLTRDIdiSNKELESFYNknkelyqfdDSYRIRHIVVKDEEEAREVLKELKGGSSFEA 185
Cdd:PRK03095  93 KQQGIKEETLKTGVRAQLAQEKAIEKTI--TDKELKDNYK---------PEIKASHILVKDEATAKKVKEELGQGKSFEE 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489336608 186 VAAERSTDRYTSPYGGDLGFVTeaSDNIPSAYIEEAKTLKEDEWSqEPIKVSNGYAIIQLKEkLKARTFSFDEVKDQIRR 265
Cdd:PRK03095 162 LAKQYSEDTGSKEKGGDLGFFG--AGKMVKEFEDAAYKLKKDEVS-EPVKSQFGYHIIKVTD-IKEPEKSFEQSKADIKK 237

                        250       260
                 ....*....|....*....|....*.
gi 489336608 266 QIAMDQLGDKATVKTLW----KEADV 287
Cdd:PRK03095 238 ELVQKKAQDGEFMNDLMmkeiKKADV 263
Rotamase_2 pfam13145
PPIC-type PPIASE domain;
135-261 5.77e-20

PPIC-type PPIASE domain;


Pssm-ID: 432992 [Multi-domain]  Cd Length: 121  Bit Score: 83.26  E-value: 5.77e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489336608  135 ISNKELESFYNKNKELYQFDDSYRIRHIVVKDEEEAREVLKELKGGSSFEAVAAERSTDRYTSPYGgdlgfVTEASDNIP 214
Cdd:pfam13145   1 VTEEELKAYYEENKDEFSTPEGRLLEILVFKDQVAADAALALLKAGALEDFAALAKGEGIKAATLD-----IVESAELLP 75

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 489336608  215 SAYIEEAKTLKEDEWSqEPIKVSNGYAIIQLKEKLKARTFSFDEVKD 261
Cdd:pfam13145  76 EELAKAAFALKPGEVS-GPIKTGNGYYVVRVTEIKPAQPLPFEEAKD 121
prsA PRK02998
peptidylprolyl isomerase; Reviewed
 9-287 9.63e-19

peptidylprolyl isomerase; Reviewed


Pssm-ID: 179522 [Multi-domain]  Cd Length: 283  Bit Score: 83.87  E-value: 9.63e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489336608   9 IILGALLVCCiavayTLTKSQAGASssgESIATIGGKSVTREEWLKEMEDQYGKSTLEDMINVRVVeqlakKNKLKISKS 88
Cdd:PRK02998   6 LFLGTIISCV-----VLALSACGSS---DNVVTSKVGNITEKELSKELRQKYGESTLYQMVLSKAL-----LDKYKVSDE 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489336608  89 EVDREFLLIK-AVNNSFYEDEHTTEKEWKDQIRYNILLEDLLTRDIDISNKELESFYNKNKELyqfddsyRIRHIVVKDE 167
Cdd:PRK02998  73 EAKKQVEEAKdKMGDNFKSTLEQVGLKNEDELKEKMKPEIAFEKAIKATVTEKDVKDNYKPEM-------KVSHILVKDE 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489336608 168 EEAREVLKELKGGSSFEAVAAERSTDRYTSPYGGDLgfvTEASDNIPSAYIEEAKTLKEDEWSQEPIKVSNGYAIIQLKE 247
Cdd:PRK02998 146 KTAKEVKEKVNNGEDFAALAKQYSEDTGSKEQGGEI---SGFAPGQTVKEFEEAAYKLDAGQVSEPVKTTYGYHIIKVTD 222

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 489336608 248 KLKARtfSFDEVKDQIRRQIAMDQLGD------KATVKTLWKEADV 287
Cdd:PRK02998 223 KKELK--PFDEVKDSIRKDLEQQRLQDttgkwkQQVVNDLLKDADI 266
PRK10788 PRK10788
periplasmic folding chaperone; Provisional
 133-267 4.68e-18

periplasmic folding chaperone; Provisional


Pssm-ID: 182731 [Multi-domain]  Cd Length: 623  Bit Score: 84.29  E-value: 4.68e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489336608 133 IDISNKELESFYNKNKElyQFDDSYRIRH--IVVKDEEEAREVLKELKGGSSFEAVAAERSTDRYTSPYGGDLGFVTEAS 210
Cdd:PRK10788 247 ITVSDADIQAYYDQHQD--QFTQPERKRYsiIQTKTEAEAKAVLDELKKGADFATLAKEKSTDIISARNGGDLGWLEPAT 324

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 489336608 211 --DNIPSAyieeakTLKEDEWSQEPIKVSNGYAIIQLKEKLKARTFSFDEVKDQIRRQI 267
Cdd:PRK10788 325 tpDELKNA------GLKEKGQLSGVIKSSVGFLIVRLDDIQPAKVKPLSEVRDDIAAKV 377
SurA_N_3 pfam13624
SurA N-terminal domain; This domain is found at the N-terminus of the chaperone SurA. It is a ...
 8-129 6.62e-11

SurA N-terminal domain; This domain is found at the N-terminus of the chaperone SurA. It is a helical domain of unknown function. The C-terminus of the SurA protein folds back and forms part of this domain also but is not included in the current alignment.


Pssm-ID: 433358 [Multi-domain]  Cd Length: 162  Bit Score: 59.51  E-value: 6.62e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489336608    8 TIILGAllvccIAVAYTLTKSQAGASSSGESIATIGGKSVTREEWLKEMEDQYG---------------------KSTLE 66
Cdd:pfam13624  15 KIILGL-----IILSFVFWGVGSYFSGGGGAVAKVNGEKISRAEFQRAYRRQLDqlrqqfgpnldaelldelglrQQVLD 89

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489336608   67 DMINVRVVEQLAKKNKLKISKSEVDREFLLIKA--VNNSF----YED----EHTTEKEWKDQIRYNILLEDLL 129
Cdd:pfam13624  90 QLIDRALLLQEAKKLGLAVSDEEVRQAIASIPAfqEDGKFdkerYRQllraNGLTPAEFEASLRQDLLLQQLL 162
Rotamase pfam00639
PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the ...
 161-247 1.35e-10

PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the interconversion of cis-proline and trans-proline.


Pssm-ID: 425792 [Multi-domain]  Cd Length: 96  Bit Score: 56.92  E-value: 1.35e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489336608  161 HIVVK-------DEEEAR----EVLKELKGG-SSFEAVAAERSTDRYTSPYGGDLGFVTeaSDNIPSAYIEEAKTLKEDE 228
Cdd:pfam00639   1 HILIKtpeaserDRAEAKakaeEILEQLKSGeDSFAELARKYSDDCPSAANGGDLGWFT--RGQLPPEFEKAAFALKPGE 78

                          90
                  ....*....|....*....
gi 489336608  229 WSqEPIKVSNGYAIIQLKE 247
Cdd:pfam00639  79 IS-GPVETRFGFHIIKLTD 96
Rotamase_3 pfam13616
PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the ...
 152-248 7.57e-08

PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the interconversion of cis-proline and trans-proline.


Pssm-ID: 404499 [Multi-domain]  Cd Length: 116  Bit Score: 50.06  E-value: 7.57e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489336608  152 QFDDSYRIRHI-------VVKDEEEAR----EVLKELKGGSSFEAVAAERSTDRYTSPYGGDLGFVTEASDNIPsaYIEE 220
Cdd:pfam13616  11 SAPDSVKASHIlisysqaVSRTEEEAKakadSLLAALKNGADFAALAKTYSDDPASKNNGGDLGWFTKGQMVKE--FEDA 88

                          90       100
                  ....*....|....*....|....*...
gi 489336608  221 AKTLKEDEWSQePIKVSNGYAIIQLKEK 248
Cdd:pfam13616  89 VFSLKVGEISG-VVKTQFGFHIIKVTDK 115
prsA PRK01326
foldase protein PrsA; Reviewed
 8-276 2.20e-06

foldase protein PrsA; Reviewed


Pssm-ID: 179281 [Multi-domain]  Cd Length: 310  Bit Score: 48.27  E-value: 2.20e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489336608   8 TIILGALLVCCIAvayTLTKSQAGasSSGESIATIGGKSVTREEWLKEMEDQygKSTLEDMINVRVVEQLAKKNKLKISK 87
Cdd:PRK01326   4 KLIAGAVTLLSVA---TLAACSKT--NENTKVISMKGDTITVSDFYNQVKNN--PSAQQAMLNLTISRVFEKQYGDKVSD 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489336608  88 SEVDREF-LLIKAVNNSFYE---DEHTTEKEWKDQIRYNILLEDLLTRdidISNKEL-ESFYNKNKELYQFDDSYRIrhI 162
Cdd:PRK01326  77 KEVEKAYaKTAKQYGASFSRalaQAGLTPETYKAQIRTSKLVEYAVKE---AAKKELtDEAYKKAYEEYTPEVTAQI--I 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489336608 163 VVKDEEEAREVLKELKG-GSSFEAVAAERSTdryTSPYGGDLGFvTEASDNIPSAYIEEAKTLKEDEWSQ-----EPIKV 236
Cdd:PRK01326 152 RLDNEDKAKSVLEEAKAeGADFAQIAKENTT---TKEKKGEYKF-DSGSTNVPEQVKKAAFALDEDGVSDvisvlDPTAY 227

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 489336608 237 SNGYAIIQLKEKLKARTfSFDEVKDQIRRQIAMDQLGDKA 276
Cdd:PRK01326 228 QSKYYIVKVTKKTEKKS-DWKDYKKRLKAIILAQKQNDSN 266
SurA_N_2 pfam13623
SurA N-terminal domain; This domain is found at the N-terminus of the chaperone SurA. It is a ...
 2-104 2.56e-05

SurA N-terminal domain; This domain is found at the N-terminus of the chaperone SurA. It is a helical domain of unknown function. The C-terminus of the SurA protein folds back and forms part of this domain also but is not included in the current alignment.


Pssm-ID: 463938  Cd Length: 145  Bit Score: 43.33  E-value: 2.56e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489336608    2 KSRTIWTIILGALLVCCIAVAyTLTKSQAGASSSGESIATIGGKSVTREEWLKE-------MEDQYG------------- 61
Cdd:pfam13623   7 KSGGLLAIIIGLALLAFIIGD-LFGVGSYLFGGSSNVVAEVNGEEISYQEFQQAvenqrnrLRQQLGqnfdpaeldeaql 85

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 489336608   62 -KSTLEDMINVRVVEQLAKKNKLKISKSEVDREFLLIKAVNNSF 104
Cdd:pfam13623  86 rEQVWDQLVREKLLLQEAEKLGLTVSDEELVDAIQGNPAILQQF 129
PRK10770 PRK10770
peptidyl-prolyl cis-trans isomerase SurA; Provisional
 160-245 1.84e-03

peptidyl-prolyl cis-trans isomerase SurA; Provisional


Pssm-ID: 236758 [Multi-domain]  Cd Length: 413  Bit Score: 39.34  E-value: 1.84e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489336608 160 RHIVVK-----DEEEAREVLKELK-----GGSSFEAVAAERSTDRYTSPYGGDLGFVTeaSDNIPSAYIEEAKTLKEDEW 229
Cdd:PRK10770 270 RHILLKpspimTDEQARAKLEQIAadiksGKTTFAAAAKEFSQDPGSANQGGDLGWAT--PDIFDPAFRDALMRLNKGQI 347

                         90
                 ....*....|....*.
gi 489336608 230 SQePIKVSNGYAIIQL 245
Cdd:PRK10770 348 SA-PVHSSFGWHLIEL 362
PRK10770 PRK10770
peptidyl-prolyl cis-trans isomerase SurA; Provisional
 65-193 2.85e-03

peptidyl-prolyl cis-trans isomerase SurA; Provisional


Pssm-ID: 236758 [Multi-domain]  Cd Length: 413  Bit Score: 38.95  E-value: 2.85e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489336608  65 LEDMINVRVVEQLAKKNKLKISKSEVDREFLLIKAVNN-------SFYEDEHTTEKEWKDQIRYNILLED---------- 127
Cdd:PRK10770  53 LERLIMDNIILQMAQKMGVKISDEQLDQAIANIAAQNNmtldqmrSRLAYDGLNYNTYRNQIRKEMIISEvrnnevrrri 132

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489336608 128 -LLTRDIDISNKELESFYNKNKELyqfddsyRIRHIVV------------KDEEEAREVLKELKGGSSFEAVAAERSTD 193
Cdd:PRK10770 133 tILPQEVDSLAKQIGNQNDASTEL-------NLSHILIplpenptqdqvdEAESQARSIVDQARNGADFGKLAIAYSAD 204
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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