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Conserved domains on  [gi|489197383|ref|WP_003106682|]
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MULTISPECIES: type II secretion system secretin GspD [Pseudomonas]

Protein Classification

type II secretion system protein D( domain architecture ID 1004622)

type II secretion system protein D is involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins

CATH:  3.30.1370.120|3.55.50.30
Gene Ontology:  GO:0015628|GO:0015627|GO:0009279
PubMed:  28067918|30767847

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
type_II_gspD super family cl37135
type II secretion system protein D; In Gram-negative bacteria, proteins that have first ...
 48-606 8.38e-160

type II secretion system protein D; In Gram-negative bacteria, proteins that have first crossed the inner member by Sec-dependent protein transport can be exported across the outer membrane by type II secretion, also called the main terminal branch of the general secretion pathway. Members of this family are general secretion pathway protein D. In Yersinia enterocolitica, a second member of this family is part of a novel second type II secretion system specifically associated with virulence (See ). This family is closely homologous to the type IV pilus outer membrane secretin PilQ (TIGR02515) and to the type III secretion system pore YscC/HrcC (TIGR02516). [Protein fate, Protein and peptide secretion and trafficking]


The actual alignment was detected with superfamily member TIGR02517:

Pssm-ID: 274175 [Multi-domain]  Cd Length: 594  Bit Score: 476.49  E-value: 8.38e-160
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383   48 INMKDAEIGDFIEQVSSISGQTFVVDPRVKGRVTVVSQARLSLAEVYQLFLSVLATHGYAVLPQGDQARIVPnmeARQDA 127
Cdd:TIGR02517   1 LNFVDADISTVVKAISDLTGKNFIIDPRVKGKITIISPRPVTEDEAYQLFLSALRAQGFAVVPEGNGYKIVV---PRAAA 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383  128 AQKTV--------RDGPGSLETRVVQAQQTSVAELIPMIRPLVPAHGHLAAVPSANALIVSDRRSNIERIEAIVRSLDRA 199
Cdd:TIGR02517  78 KLSPGpiedgpapGVGGDQFVTRVFPLRNISASELVPVLRPLVSPNGDVAAYPPTNTIVVTDYASNINRVARIIQQLDVD 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383  200 GEHDYSIYDMRHAWVAEIAEVLDR-SVTPAAGKSAATVQVLADSRSNRLVLLGP-PQARARLLRLAQSLDVPSSRSANSR 277
Cdd:TIGR02517 158 GAGSVEVIPLKNASAVDIADVLNKlLGEGGKTDGGGKLSVIAPDRRNNILIRAGsPEALERIKKLISQLDVPASEGGNVR 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383  278 VIRLRHGDAKTLAATLGEIGESLhGERGQDGRGSGKRGLL--------------------VRADESLNALVILADPEDVG 337
Cdd:TIGR02517 238 VYYLRNADAEELAKTLQGVFGGG-GNEPGSSSSPGLGGAVnpggsqsaqaassasggsvsGSADKATNSLIITASPQDYK 316

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383  338 LLEDIVRQLDVPRAQLLVEAAIVELSGEIGDALGVQWALRSGHvaGGAGFADSGLSIGTLLGALQAGKPPAELPDGAIVG 417
Cdd:TIGR02517 317 NIRAVIKQLDVRRAQVLVEAIIVEVSLDDALELGVQWLIAGTG--GGVNFSTGSPNSGSLLGASASAISLGSAGIGLLVT 394

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383  418 -----------LGSRDFGALVTALSRNSRSNLLSTPSLLTLDNQKAEILVGQNVPFQTGSYTTS-ASGSSNPFTTVERKD 485
Cdd:TIGR02517 395 sssttsgvggtGGGPNLGVLLNALKQDTGFNVLSTPSLLTLDNQEAEINVGQEVPVLTGSYNTGtGGTNANPFNTYQRKD 474

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383  486 IGVTLKVTPHIGEDRMLRLEIEQEISSIAPTATLAAkAVDLVTNKRSIKSTVLADDGQVIVLGGLIQDDLQRSDSRVPLL 565
Cdd:TIGR02517 475 VGIKLKVTPQINEGGTVRLEIYQEVSSVAPTTVGSA-ASGPTFNKREIKTVVLVDNGDTVVLGGLIQDKTSESVTKVPLL 553

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|.
gi 489197383  566 GDIPGVGRLFRSSRETRVKRNLMVFLRPSIVRDAAGLERIS 606
Cdd:TIGR02517 554 GDIPVLGWLFRSTTTERTKTNLMVFITPRIIRDPEDARALT 594
 
Name Accession Description Interval E-value
type_II_gspD TIGR02517
type II secretion system protein D; In Gram-negative bacteria, proteins that have first ...
 48-606 8.38e-160

type II secretion system protein D; In Gram-negative bacteria, proteins that have first crossed the inner member by Sec-dependent protein transport can be exported across the outer membrane by type II secretion, also called the main terminal branch of the general secretion pathway. Members of this family are general secretion pathway protein D. In Yersinia enterocolitica, a second member of this family is part of a novel second type II secretion system specifically associated with virulence (See ). This family is closely homologous to the type IV pilus outer membrane secretin PilQ (TIGR02515) and to the type III secretion system pore YscC/HrcC (TIGR02516). [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274175 [Multi-domain]  Cd Length: 594  Bit Score: 476.49  E-value: 8.38e-160
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383   48 INMKDAEIGDFIEQVSSISGQTFVVDPRVKGRVTVVSQARLSLAEVYQLFLSVLATHGYAVLPQGDQARIVPnmeARQDA 127
Cdd:TIGR02517   1 LNFVDADISTVVKAISDLTGKNFIIDPRVKGKITIISPRPVTEDEAYQLFLSALRAQGFAVVPEGNGYKIVV---PRAAA 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383  128 AQKTV--------RDGPGSLETRVVQAQQTSVAELIPMIRPLVPAHGHLAAVPSANALIVSDRRSNIERIEAIVRSLDRA 199
Cdd:TIGR02517  78 KLSPGpiedgpapGVGGDQFVTRVFPLRNISASELVPVLRPLVSPNGDVAAYPPTNTIVVTDYASNINRVARIIQQLDVD 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383  200 GEHDYSIYDMRHAWVAEIAEVLDR-SVTPAAGKSAATVQVLADSRSNRLVLLGP-PQARARLLRLAQSLDVPSSRSANSR 277
Cdd:TIGR02517 158 GAGSVEVIPLKNASAVDIADVLNKlLGEGGKTDGGGKLSVIAPDRRNNILIRAGsPEALERIKKLISQLDVPASEGGNVR 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383  278 VIRLRHGDAKTLAATLGEIGESLhGERGQDGRGSGKRGLL--------------------VRADESLNALVILADPEDVG 337
Cdd:TIGR02517 238 VYYLRNADAEELAKTLQGVFGGG-GNEPGSSSSPGLGGAVnpggsqsaqaassasggsvsGSADKATNSLIITASPQDYK 316

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383  338 LLEDIVRQLDVPRAQLLVEAAIVELSGEIGDALGVQWALRSGHvaGGAGFADSGLSIGTLLGALQAGKPPAELPDGAIVG 417
Cdd:TIGR02517 317 NIRAVIKQLDVRRAQVLVEAIIVEVSLDDALELGVQWLIAGTG--GGVNFSTGSPNSGSLLGASASAISLGSAGIGLLVT 394

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383  418 -----------LGSRDFGALVTALSRNSRSNLLSTPSLLTLDNQKAEILVGQNVPFQTGSYTTS-ASGSSNPFTTVERKD 485
Cdd:TIGR02517 395 sssttsgvggtGGGPNLGVLLNALKQDTGFNVLSTPSLLTLDNQEAEINVGQEVPVLTGSYNTGtGGTNANPFNTYQRKD 474

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383  486 IGVTLKVTPHIGEDRMLRLEIEQEISSIAPTATLAAkAVDLVTNKRSIKSTVLADDGQVIVLGGLIQDDLQRSDSRVPLL 565
Cdd:TIGR02517 475 VGIKLKVTPQINEGGTVRLEIYQEVSSVAPTTVGSA-ASGPTFNKREIKTVVLVDNGDTVVLGGLIQDKTSESVTKVPLL 553

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|.
gi 489197383  566 GDIPGVGRLFRSSRETRVKRNLMVFLRPSIVRDAAGLERIS 606
Cdd:TIGR02517 554 GDIPVLGWLFRSTTTERTKTNLMVFITPRIIRDPEDARALT 594
PulD COG1450
Type II secretory pathway component GspD/PulD (secretin) [Intracellular trafficking, secretion, ...
 278-614 7.91e-94

Type II secretory pathway component GspD/PulD (secretin) [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 441059 [Multi-domain]  Cd Length: 333  Bit Score: 296.06  E-value: 7.91e-94
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383 278 VIRLRHGDAKTLAATLGEIGeslhgergqdgrgSGKRGLLVRADESLNALVILADPEDVGLLEDIVRQLDVPRAQLLVEA 357
Cdd:COG1450   19 VLRALYADAEDLAKVLRSLL-------------GGAAGVSVVADPRTNSLIVRATPEQLREIEELIEQLDVPRRQVLIEA 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383 358 AIVELSGEIGDALGVQWALRSGHvAGGAGFADSGlSIGTLLGAlqagkppAELPDGAIVGL-GSRDFGALVTALSRNSRS 436
Cdd:COG1450   86 KIVEVSLSDLRELGIDWSALGGN-GGGVNFGGTG-SLGSLAAA-------GSLGGGLNLGLlGGGNFGALLNALESNGDA 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383 437 NLLSTPSLLTLDNQKAEILVGQNVPFQTGSYTTSASGssNPFTTVERKDIGVTLKVTPHIGEDRMLRLEIEQEISSIAPT 516
Cdd:COG1450  157 NVLSSPSILTLNNQEAVIKVGQTVPYVTGSTTTSSTG--NPTTTIEYVDVGITLKVTPQINEDGTVTLDINPEVSSVTGS 234

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383 517 ATlAAKAVDLVTNKRSIKSTVLADDGQVIVLGGLIQDDLQRSDSRVPLLGDIPGVGRLFRSSRETRVKRNLMVFLRPSIV 596
Cdd:COG1450  235 TT-GGGNGLPTINKREISTTVRVKDGQTVVLGGLIRDEESESESKVPLLGDIPLLGRLFRSTSKSKEKTELVIFITPTII 313

                        330
                 ....*....|....*...
gi 489197383 597 RDAAGLERIShGRYRSIQ 614
Cdd:COG1450  314 RDGEDAQALT-EEYDRLR 330
IV PHA00019
phage assembly protein
 47-597 2.18e-52

phage assembly protein


Pssm-ID: 222772 [Multi-domain]  Cd Length: 428  Bit Score: 188.10  E-value: 2.18e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383  47 TINMKDAEIGDFIEQVSSISGQTFVVDPRVKGRVTVVSqARLSLAEVYQLFLSVLATHGYAVLPQGDQ--ARIVPNMEAR 124
Cdd:PHA00019  25 PVELNNSPIREFVSWYSQQTGKSVVLGPDVKGNVTVYS-ADVNPANLPQFFDSVLRANGFDLVAGGPAvvIKQNPNQEDY 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383 125 QDAAQKTVRDGPgsletrvvqaqqtsvaelipmirplvpahgHLAAVPSANALIVSDrrsnierieAIVRsldragehdy 204
Cdd:PHA00019 104 ADDLRDSRDDVF------------------------------YDNSVPSGAPEVPND---------LIVR---------- 134

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383 205 sIYDMRHAWVAEIAEVLDRSVTpaaGKSAATVQVLADSRSNRLVLLGPpqararllrlAQSLDVpssrsansrvirlrhg 284
Cdd:PHA00019 135 -TFNINNVRASDLLPLVKIFVK---SNGAPGGSVTDLPGTNSLVVSGS----------ASQLPA---------------- 184

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383 285 daktlaatlgeigeslhgergqdgrgsgkrgllvradeslnalviladpedvglLEDIVRQLDVPRAQLLVEAAIVELSg 364
Cdd:PHA00019 185 ------------------------------------------------------LADFISAIDVPRRQVLIEALIFETS- 209

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383 365 eIGDalGVQWALRSGHVAGGA---GFADSGLsiGTLLGAlqAGkppaelpdGAIVGLGSRDFGALVTALSRNSRSNLLST 441
Cdd:PHA00019 210 -LGD--GVDLSFAAGLASGGKvagGFNTARL--TTVLSS--AG--------GSFGIFNGNVLGLSVKALENSSNSRVLSR 274

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383 442 PSLLTLDNQKAEILVGQNVPFQTGSYTTSASGSSNPFTTVERKDIGVTLKVTPHIGEDRMLRLEIEQEISSIAPTATlaa 521
Cdd:PHA00019 275 PRILTLSGQSGYISVGQNVPFVTGRVTGEAANVNNPFQTIERKDVGVSLEVTPVVMGDGQLVLDIDTKADSLSDSTI--- 351

                        490       500       510       520       530       540       550
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489197383 522 kAVDLVTNKRSIKSTVLADDGQVIVLGGLIQDDLQRSDSRVPLLGDIPGVGRLFRSSRETRVKRNLMVFLRPSIVR 597
Cdd:PHA00019 352 -ASDIITNQRSLQTTVQVKDGQTLLLGGLISSNNTDGDSSVPFLSKIPLIGWLFRSKSDSNEQRTLYVLLTARVIK 426
Secretin pfam00263
Bacterial type II and III secretion system protein;
429-596 4.36e-49

Bacterial type II and III secretion system protein;


Pssm-ID: 459738 [Multi-domain]  Cd Length: 159  Bit Score: 170.01  E-value: 4.36e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383  429 ALSRNSRSNLLSTPSLLTLDNQKAEILVGQNVPFQTGSYTTSASGssnpfTTVERKDIGVTLKVTPHIGEDRMLRLEIEQ 508
Cdd:pfam00263   1 ALEQNGKAKILSSPSLLTLDNQEASIKVGQEVPVPTTSTTGGTTT-----TTVEFKDAGLSLKVTPQVTPDGTITLKINP 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383  509 EISSIAPTATlaakAVDLVTNKRSIKSTVLADDGQVIVLGGLIQDDLQRSDSRVPLLGDIPGVGRLFRSSRETRVKRNLM 588
Cdd:pfam00263  76 EVSSPDGNGG----NGVPTINTREISTTVRVKDGQTVVIGGLIQEEDSETESKVPLLGDIPLLGALFRSTSKSKEKTELL 151


                  ....*...
gi 489197383  589 VFLRPSIV 596
Cdd:pfam00263 152 IFITPRIV 159
 
Name Accession Description Interval E-value
type_II_gspD TIGR02517
type II secretion system protein D; In Gram-negative bacteria, proteins that have first ...
 48-606 8.38e-160

type II secretion system protein D; In Gram-negative bacteria, proteins that have first crossed the inner member by Sec-dependent protein transport can be exported across the outer membrane by type II secretion, also called the main terminal branch of the general secretion pathway. Members of this family are general secretion pathway protein D. In Yersinia enterocolitica, a second member of this family is part of a novel second type II secretion system specifically associated with virulence (See ). This family is closely homologous to the type IV pilus outer membrane secretin PilQ (TIGR02515) and to the type III secretion system pore YscC/HrcC (TIGR02516). [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274175 [Multi-domain]  Cd Length: 594  Bit Score: 476.49  E-value: 8.38e-160
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383   48 INMKDAEIGDFIEQVSSISGQTFVVDPRVKGRVTVVSQARLSLAEVYQLFLSVLATHGYAVLPQGDQARIVPnmeARQDA 127
Cdd:TIGR02517   1 LNFVDADISTVVKAISDLTGKNFIIDPRVKGKITIISPRPVTEDEAYQLFLSALRAQGFAVVPEGNGYKIVV---PRAAA 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383  128 AQKTV--------RDGPGSLETRVVQAQQTSVAELIPMIRPLVPAHGHLAAVPSANALIVSDRRSNIERIEAIVRSLDRA 199
Cdd:TIGR02517  78 KLSPGpiedgpapGVGGDQFVTRVFPLRNISASELVPVLRPLVSPNGDVAAYPPTNTIVVTDYASNINRVARIIQQLDVD 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383  200 GEHDYSIYDMRHAWVAEIAEVLDR-SVTPAAGKSAATVQVLADSRSNRLVLLGP-PQARARLLRLAQSLDVPSSRSANSR 277
Cdd:TIGR02517 158 GAGSVEVIPLKNASAVDIADVLNKlLGEGGKTDGGGKLSVIAPDRRNNILIRAGsPEALERIKKLISQLDVPASEGGNVR 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383  278 VIRLRHGDAKTLAATLGEIGESLhGERGQDGRGSGKRGLL--------------------VRADESLNALVILADPEDVG 337
Cdd:TIGR02517 238 VYYLRNADAEELAKTLQGVFGGG-GNEPGSSSSPGLGGAVnpggsqsaqaassasggsvsGSADKATNSLIITASPQDYK 316

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383  338 LLEDIVRQLDVPRAQLLVEAAIVELSGEIGDALGVQWALRSGHvaGGAGFADSGLSIGTLLGALQAGKPPAELPDGAIVG 417
Cdd:TIGR02517 317 NIRAVIKQLDVRRAQVLVEAIIVEVSLDDALELGVQWLIAGTG--GGVNFSTGSPNSGSLLGASASAISLGSAGIGLLVT 394

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383  418 -----------LGSRDFGALVTALSRNSRSNLLSTPSLLTLDNQKAEILVGQNVPFQTGSYTTS-ASGSSNPFTTVERKD 485
Cdd:TIGR02517 395 sssttsgvggtGGGPNLGVLLNALKQDTGFNVLSTPSLLTLDNQEAEINVGQEVPVLTGSYNTGtGGTNANPFNTYQRKD 474

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383  486 IGVTLKVTPHIGEDRMLRLEIEQEISSIAPTATLAAkAVDLVTNKRSIKSTVLADDGQVIVLGGLIQDDLQRSDSRVPLL 565
Cdd:TIGR02517 475 VGIKLKVTPQINEGGTVRLEIYQEVSSVAPTTVGSA-ASGPTFNKREIKTVVLVDNGDTVVLGGLIQDKTSESVTKVPLL 553

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|.
gi 489197383  566 GDIPGVGRLFRSSRETRVKRNLMVFLRPSIVRDAAGLERIS 606
Cdd:TIGR02517 554 GDIPVLGWLFRSTTTERTKTNLMVFITPRIIRDPEDARALT 594
PulD COG1450
Type II secretory pathway component GspD/PulD (secretin) [Intracellular trafficking, secretion, ...
 278-614 7.91e-94

Type II secretory pathway component GspD/PulD (secretin) [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 441059 [Multi-domain]  Cd Length: 333  Bit Score: 296.06  E-value: 7.91e-94
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383 278 VIRLRHGDAKTLAATLGEIGeslhgergqdgrgSGKRGLLVRADESLNALVILADPEDVGLLEDIVRQLDVPRAQLLVEA 357
Cdd:COG1450   19 VLRALYADAEDLAKVLRSLL-------------GGAAGVSVVADPRTNSLIVRATPEQLREIEELIEQLDVPRRQVLIEA 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383 358 AIVELSGEIGDALGVQWALRSGHvAGGAGFADSGlSIGTLLGAlqagkppAELPDGAIVGL-GSRDFGALVTALSRNSRS 436
Cdd:COG1450   86 KIVEVSLSDLRELGIDWSALGGN-GGGVNFGGTG-SLGSLAAA-------GSLGGGLNLGLlGGGNFGALLNALESNGDA 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383 437 NLLSTPSLLTLDNQKAEILVGQNVPFQTGSYTTSASGssNPFTTVERKDIGVTLKVTPHIGEDRMLRLEIEQEISSIAPT 516
Cdd:COG1450  157 NVLSSPSILTLNNQEAVIKVGQTVPYVTGSTTTSSTG--NPTTTIEYVDVGITLKVTPQINEDGTVTLDINPEVSSVTGS 234

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383 517 ATlAAKAVDLVTNKRSIKSTVLADDGQVIVLGGLIQDDLQRSDSRVPLLGDIPGVGRLFRSSRETRVKRNLMVFLRPSIV 596
Cdd:COG1450  235 TT-GGGNGLPTINKREISTTVRVKDGQTVVLGGLIRDEESESESKVPLLGDIPLLGRLFRSTSKSKEKTELVIFITPTII 313

                        330
                 ....*....|....*...
gi 489197383 597 RDAAGLERIShGRYRSIQ 614
Cdd:COG1450  314 RDGEDAQALT-EEYDRLR 330
IV PHA00019
phage assembly protein
 47-597 2.18e-52

phage assembly protein


Pssm-ID: 222772 [Multi-domain]  Cd Length: 428  Bit Score: 188.10  E-value: 2.18e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383  47 TINMKDAEIGDFIEQVSSISGQTFVVDPRVKGRVTVVSqARLSLAEVYQLFLSVLATHGYAVLPQGDQ--ARIVPNMEAR 124
Cdd:PHA00019  25 PVELNNSPIREFVSWYSQQTGKSVVLGPDVKGNVTVYS-ADVNPANLPQFFDSVLRANGFDLVAGGPAvvIKQNPNQEDY 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383 125 QDAAQKTVRDGPgsletrvvqaqqtsvaelipmirplvpahgHLAAVPSANALIVSDrrsnierieAIVRsldragehdy 204
Cdd:PHA00019 104 ADDLRDSRDDVF------------------------------YDNSVPSGAPEVPND---------LIVR---------- 134

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383 205 sIYDMRHAWVAEIAEVLDRSVTpaaGKSAATVQVLADSRSNRLVLLGPpqararllrlAQSLDVpssrsansrvirlrhg 284
Cdd:PHA00019 135 -TFNINNVRASDLLPLVKIFVK---SNGAPGGSVTDLPGTNSLVVSGS----------ASQLPA---------------- 184

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383 285 daktlaatlgeigeslhgergqdgrgsgkrgllvradeslnalviladpedvglLEDIVRQLDVPRAQLLVEAAIVELSg 364
Cdd:PHA00019 185 ------------------------------------------------------LADFISAIDVPRRQVLIEALIFETS- 209

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383 365 eIGDalGVQWALRSGHVAGGA---GFADSGLsiGTLLGAlqAGkppaelpdGAIVGLGSRDFGALVTALSRNSRSNLLST 441
Cdd:PHA00019 210 -LGD--GVDLSFAAGLASGGKvagGFNTARL--TTVLSS--AG--------GSFGIFNGNVLGLSVKALENSSNSRVLSR 274

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383 442 PSLLTLDNQKAEILVGQNVPFQTGSYTTSASGSSNPFTTVERKDIGVTLKVTPHIGEDRMLRLEIEQEISSIAPTATlaa 521
Cdd:PHA00019 275 PRILTLSGQSGYISVGQNVPFVTGRVTGEAANVNNPFQTIERKDVGVSLEVTPVVMGDGQLVLDIDTKADSLSDSTI--- 351

                        490       500       510       520       530       540       550
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489197383 522 kAVDLVTNKRSIKSTVLADDGQVIVLGGLIQDDLQRSDSRVPLLGDIPGVGRLFRSSRETRVKRNLMVFLRPSIVR 597
Cdd:PHA00019 352 -ASDIITNQRSLQTTVQVKDGQTLLLGGLISSNNTDGDSSVPFLSKIPLIGWLFRSKSDSNEQRTLYVLLTARVIK 426
HofQ COG4796
Type II secretory pathway, component HofQ [Intracellular trafficking, secretion, and vesicular ...
 276-599 3.72e-49

Type II secretory pathway, component HofQ [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443824 [Multi-domain]  Cd Length: 570  Bit Score: 182.36  E-value: 3.72e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383 276 SRVIRLRHGDAKTLAATLGEIGESLHGERGQdgrgsgkrgllVRADESLNALVILADPEDVGLLEDIVRQLDVPRAQLLV 355
Cdd:COG4796  258 TEYIQLNYAKASDLAKLLKGQRGSLLSERGS-----------VTVDERTNTLIVRDTPSKLEEIRRLIAKLDIPVRQVLI 326

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383 356 EAAIVELSGEIGDALGVQWALRSGHVAGGAGFADSGLSIGTLLGALQAGKP-----PAELPDGAI-VGLGSRDFGALV-- 427
Cdd:COG4796  327 EARIVEASDSFSRELGVRWGGSGANGTGNNRGGIGGSLNGTTAGTPLLPDGlnvnlPAANPAGSLgLTLAKLGGGRLLdl 406

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383 428 --TALSRNSRSNLLSTPSLLTLDNQKAEILVGQNVPFQTgsytTSASGSsnpfTTVERKDIGVTLKVTPHIGEDRMLRLE 505
Cdd:COG4796  407 elSALEAEGKGEIISSPRVITADQQEASIEQGTEIPYQE----SSSSGA----TSVEFKEAVLSLEVTPQITPDGRIILD 478

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383 506 IEQEISSIAPTATLAAKAVDlvtnKRSIKSTVLADDGQVIVLGGLIQDDLQRSDSRVPLLGDIPGVGRLFRSSRETRVKR 585
Cdd:COG4796  479 LDVSKDSPGETVAGGVPAID----TKEIKTQVLVENGETVVLGGIYEQTESNSVDKVPFLGDIPLLGWLFKNTTKTDEKR 554

                        330
                 ....*....|....
gi 489197383 586 NLMVFLRPSIVRDA 599
Cdd:COG4796  555 ELLIFITPRIVKDA 568
Secretin pfam00263
Bacterial type II and III secretion system protein;
429-596 4.36e-49

Bacterial type II and III secretion system protein;


Pssm-ID: 459738 [Multi-domain]  Cd Length: 159  Bit Score: 170.01  E-value: 4.36e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383  429 ALSRNSRSNLLSTPSLLTLDNQKAEILVGQNVPFQTGSYTTSASGssnpfTTVERKDIGVTLKVTPHIGEDRMLRLEIEQ 508
Cdd:pfam00263   1 ALEQNGKAKILSSPSLLTLDNQEASIKVGQEVPVPTTSTTGGTTT-----TTVEFKDAGLSLKVTPQVTPDGTITLKINP 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383  509 EISSIAPTATlaakAVDLVTNKRSIKSTVLADDGQVIVLGGLIQDDLQRSDSRVPLLGDIPGVGRLFRSSRETRVKRNLM 588
Cdd:pfam00263  76 EVSSPDGNGG----NGVPTINTREISTTVRVKDGQTVVIGGLIQEEDSETESKVPLLGDIPLLGALFRSTSKSKEKTELL 151


                  ....*...
gi 489197383  589 VFLRPSIV 596
Cdd:pfam00263 152 IFITPRIV 159
IV_pilus_PilQ TIGR02515
type IV pilus secretin (or competence protein) PilQ; A number of proteins homologous to PilQ ...
 276-597 1.37e-40

type IV pilus secretin (or competence protein) PilQ; A number of proteins homologous to PilQ are involved in type IV pilus formation, competence for transformation, type III secretion, and type II secretion (also called the main terminal branch of the general secretion pathway). Members of this family include PilQ itself, which is a component of the type IV pilus structure, from a number of species. In Haemophilus influenzae, the member of this family is associated with competence for transformation with exogenous DNA rather than with formation of a type IV pilus; the surface structure required for competence may be considered an unusual, incomplete type IV pilus structure. [Cell envelope, Surface structures]


Pssm-ID: 274173 [Multi-domain]  Cd Length: 418  Bit Score: 154.39  E-value: 1.37e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383  276 SRVIRLRHGDAktlaatlGEIGESLHGERGQDGRGSGKRGLLVrADESLNALVILADPEDVGLLEDIVRQLDVPRAQLLV 355
Cdd:TIGR02515  99 TELIQLNYAKA-------SDIAKVLTGVTGGSGGLLSPRGSVT-VDPRTNTLIVTDTPENLARIRKLIAELDIPVRQVLI 170

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383  356 EAAIVELSGEIGDALGVQWALRSGHVAGGAGFADSGLSIGTLlGALQAGKPPAELPDGAIVGLGSR-------------- 421
Cdd:TIGR02515 171 EARIVEATDSFSRELGVRWGITDKNGNGNGTAGGIGGNNGTT-ATGAGGTGNPPFGDNLNVNLATAttaagisfalgkig 249

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383  422 DFGAL---VTALSRNSRSNLLSTPSLLTLDNQKAEILVGQNVPFQTgsytTSASGSsnpfTTVERKDIGVTLKVTPHIGE 498
Cdd:TIGR02515 250 SGRLLdleLSALESEGKGEIISSPRVLTANNKEAKIEQGTEIPYQQ----TSSSGA----TSVEFKEAVLSLEVTPQITP 321

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383  499 DRMLRLEIEQEISSIAPTATLAAKAVDLvtNKRSIKSTVLADDGQVIVLGGLIQDDLQRSDSRVPLLGDIPGVGRLFRSS 578
Cdd:TIGR02515 322 DGRIIMDLLVSKDSPGVVAQAGGGVPAI--DKQEINTQVLVKNGETVVIGGIYEQTQTNSEDKVPLLGDIPVLGNLFKKT 399

                         330
                  ....*....|....*....
gi 489197383  579 RETRVKRNLMVFLRPSIVR 597
Cdd:TIGR02515 400 GKSDEKSELLIFITPRIVN 418
hofQ PRK13568
DNA uptake porin HofQ;
243-599 5.98e-32

DNA uptake porin HofQ;


Pssm-ID: 237430 [Multi-domain]  Cd Length: 381  Bit Score: 128.31  E-value: 5.98e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383 243 RSNRLVLLGPPQARARLLRLAQSLDVPSSRSA--NSRVIRLRHGDAKtlaatlgEIGESLHGERGQ--DGRGSgkrgllV 318
Cdd:PRK13568  49 REGNVLMVFPEQEIQERQQKTKQQAAPQEQMLplANLTLTLQYADAE-------EVADSLQSQRGGllSPRGS------V 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383 319 RADESLNALVILADPEDVGLLEDIVRQLDVPRAQLLVEAAIVELSGEIGDALGVQWALRSGHVAGGAgFADSGLSIGTLL 398
Cdd:PRK13568 116 TADKRTNTLLIRDTPAALAQLKNWLIELDLPLQQVQLAAHIVTISSESLQELGVRWGMGEGKQGNTA-LRINDFNVNLPL 194

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383 399 G--ALQAGKPPAELpDGAIVGLGsrdfgalVTALSRNSRSNLLSTPSLLTLDNQKAEILVGQNVPFQTGSyttSASGSsn 476
Cdd:PRK13568 195 PnpAASAGFHLARL-GGRLLDLE-------LSALEQENQVDIIASPRLFTSHQQTASIKQGTEIPYTVSS---GKSGS-- 261

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383 477 pfTTVERKDIGVTLKVTPHI-GEDRM-LRLEIEQEIssiaPTATL-AAKAVDLVTNKRSIKSTVLADDGQVIVLGGLIQD 553
Cdd:PRK13568 262 --TSIEFKEAVLGMEVTPKIlRNGRItLKLKISQNM----PGRTIkRGEGEMLAIDKQEIQTQVTVKDGETIVLGGIFQQ 335

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*.
gi 489197383 554 DLQRSDSRVPLLGDIPGVGRLFRSSRETRVKRNLMVFLRPSIVRDA 599
Cdd:PRK13568 336 QKRQSVNKVPLLGDIPLLGALFRQDTQQQSRRELVIFITPKLISAD 381
pilus_MshL TIGR02519
pilus (MSHA type) biogenesis protein MshL; Members of this family are predicted secretins, ...
 327-596 9.44e-32

pilus (MSHA type) biogenesis protein MshL; Members of this family are predicted secretins, that is, outer membrane pore proteins associated with delivery of proteins from periplasm to the outside of the cell. Related families include GspD of type II secretion (TIGR02517), the YscC/HrcC family from type III secretion (TIGR02516), and the PilQ secretin of type IV pilus formation (TIGR02515). Members of this family are found in gene clusters associated with MSHA (mannose-sensitive hemagglutinin) and related pili, and appear to be the secretin of this pilus system. [Cell envelope, Surface structures]


Pssm-ID: 274176 [Multi-domain]  Cd Length: 290  Bit Score: 125.57  E-value: 9.44e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383  327 LVILADPEDVGLLEDIVRQL-DVPRAQLLVEAAIVELSGEIGDALGVQWALRSGHVAG---GAGFADSGLSIGTLLGALQ 402
Cdd:TIGR02519  10 LTVTATPAQIRRVEEYLESLqERIHRQVLIEAKILEVTLSDNHQQGIDWSNFNGSGLArykALGAANSNDSSGNQFSSGL 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383  403 AGKPPAELPDGAIVGlgsRDFGALVTALSRNSRSNLLSTPSLLTLDNQKAEILVGQNVPFQTG-SYTTSASGS---SNPF 478
Cdd:TIGR02519  90 GFLDNIGLPTGVNSG---FGFDSIINFLATFGDTKVLSNPKVMALNNQPAVISVGDNIRYVTEeSSTGTTGGTtstASSD 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383  479 TTVERKDIGVTLKVTPHIGEDRMLRLEIEQEISSIAPTATLAAKAVDLV------TNKRSIKSTVLADDGQVIVLGGLIQ 552
Cdd:TIGR02519 167 TRVDSVFSGIVLGVTPQISDDGKVILNVHPSISEVKPQSIDLNPVGNGAevalpeISVKEMSSVLRVKDGDTVVLGGLID 246

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 489197383  553 DDLQRSDSRVPLLGDIPGVGRLFRSSRETRVKRNLMVFLRPSIV 596
Cdd:TIGR02519 247 KKKSNTKTGLPFLGDIPGLGYLFGYKSKSKKKTELVIIIRPSVV 290
CpaC COG4964
Flp pilus assembly protein, secretin CpaC [Intracellular trafficking, secretion, and vesicular ...
 340-597 1.87e-29

Flp pilus assembly protein, secretin CpaC [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 443990 [Multi-domain]  Cd Length: 456  Bit Score: 122.29  E-value: 1.87e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383 340 EDIVRQLDVPRA-QLLVEAAIVELSGEIGDALGVQWALrsghvAGGAGFADSGLSIGTLLGALQAGKPPAELpdgAIVGL 418
Cdd:COG4964  163 GKVINLLTVGGPqQVMLKVRVAEVSRSVLKQLGINWSG-----LGSSGGFSFGLLTGGLLSGLLGGATAGAF---SGFGF 234

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383 419 GSRDFGALVTALSRNS------------RSNllstpslltldnQKAEILVGQNVPFQTGSyttsasgsSNPFTTVERKDI 486
Cdd:COG4964  235 GNASISATLDALEQNGlarvlaepnltaLSG------------ETASFLAGGEFPIPVAQ--------GDGTITVEYKEF 294

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383 487 GVTLKVTPHIGEDRMLRLEIEQEISSIAPTATLAAKAVDLVT-NKRSIKSTVLADDGQVIVLGGLIQDDLQRSDSRVPLL 565
Cdd:COG4964  295 GVSLNFTPTVLSNGRISLKVAPEVSELDPSNAVTLNGITIPGlTTRRAETTVELRSGQSFAIAGLLSSNTRQNVSKVPGL 374

                        250       260       270
                 ....*....|....*....|....*....|..
gi 489197383 566 GDIPGVGRLFRSSRETRVKRNLMVFLRPSIVR 597
Cdd:COG4964  375 GDIPILGALFRSRSFQRNETELVIIVTPYLVK 406
type_III_yscC TIGR02516
type III secretion outer membrane pore, YscC/HrcC family; A number of proteins homologous to ...
 209-598 1.37e-27

type III secretion outer membrane pore, YscC/HrcC family; A number of proteins homologous to the type IV pilus secretin PilQ (TIGR02515) are involved in type IV pilus formation, competence for transformation, type III secretion, and type II secretion (also called the main terminal branch of the general secretion pathway). The clade described by this model contains the outer membrane pore proteins of bacterial type III secretion systems, typified by YscC for animal pathogens and HrcC for plant pathogens. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]


Pssm-ID: 274174 [Multi-domain]  Cd Length: 462  Bit Score: 117.09  E-value: 1.37e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383  209 MRHAWVAEIAEVLDRSVTpaAGKSAAtvqVLADSRSNRLVLLGPPQARARLLRLAQSLD-VPSSRSANS---RVIRLRHG 284
Cdd:TIGR02516  82 PRPLSANELKKALRRSGL--YDPRFP---WRGDPEEGTVYVSGPPAYIDLVRNAATALEkQDQGRAGNRqvvKVFPLKYA 156

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383  285 ----------DAKTLAATLGEIGESLHGERGQDgRGSGKRGLLVR--ADESLNALVILADPEDVGLLEDIVRQLDVPRAQ 352
Cdd:TIGR02516 157 sasdrtynyrDQKVTIPGVATILRRLLSGGRQG-AGGGRASASPKisADPRTNAVLIRDRPERMAIYEQLIQQLDVPPRL 235

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383  353 LLVEAAIVELSGEIGDALGVQWalrSGHVAGGAGFADSGLSIGTLLGALQagkppaelpdGAIVGLGSRDFGALVTALSR 432
Cdd:TIGR02516 236 IEISAWIIDIDASDLSQLGVDW---QATLGAGDRQTGFNVSAGAGLGATG----------SSIVTSDGDYFMARVNALEQ 302

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383  433 NSRSNLLSTPSLLTLDNQKAeiLVGQNVPFqtgsYTTsASGssnpFTTVERKDI--GVTLKVTPHIGEDRMLRLEIEQEI 510
Cdd:TIGR02516 303 TGKAKIVSRPSVLTLENVQA--VLDNNRTF----YVK-VSG----ERVADLESVtaGTSLRVTPRVIGDEGAQRQIKLNV 371

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383  511 S-SIAPTATLAAKAVD-LVTNKRSIKSTV-LADDGQVIVLGGLIQDDLQRSDSRVPLLGDIPGVGRLFRSSREtRVKRNL 587
Cdd:TIGR02516 372 DiEDGQQKTDGTSTVDaLPEIKRTEINTQaRVGHGQSLLIGGYYRDESADSVDGIPLLGDIPLLGNLFRSTSK-EKSRVV 450

                         410
                  ....*....|..
gi 489197383  588 MVFL-RPSIVRD 598
Cdd:TIGR02516 451 RLFLiTPKIVRD 462
hofQ PRK10560
outer membrane porin HofQ; Provisional
 254-596 6.68e-22

outer membrane porin HofQ; Provisional


Pssm-ID: 182549 [Multi-domain]  Cd Length: 386  Bit Score: 98.74  E-value: 6.68e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383 254 QARARLLRLAQSLDVPssrsANSRVIRLRHGDAKTLAATlgeigeslhGERGQDGRGSgkrgllVRADESLNALVILADP 333
Cdd:PRK10560  75 IARQEAEQARAQANLP----LENRSITLQYADAGELAKA---------GEKLLSAKGS------MTVDKRTNRLLLRDNK 135

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383 334 EDVGLLEDIVRQLDVPRAQLLVEAAIVELSGEIGDALGVQWALRSGHVAGGAGfadsglSIGTLLGALQAGKPPAELpdG 413
Cdd:PRK10560 136 TALSALEQWVAQMDLPVGQVELAAHIVTINEKSLRELGVKWTLADAQQAGGVG------QVTTLGSDLSVATATTRV--G 207

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383 414 AIVG-LGSRDFGALVTALSRNSRSNLLSTPSLLTLDNQKAEILVGQNVPFQTGSYTTSAsgssnpfTTVERKDIGVTLKV 492
Cdd:PRK10560 208 FNIGrINGRLLDLELSALEQKQQLDIIASPRLLASHLQPASIKQGSEIPYQVSSGESGA-------TSVEFKEAVLGMEV 280

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383 493 TPHIGEDRMLRLEIEqeISSIAPTATLA-AKAVDLVTNKRSIKSTVLADDGQVIVLGGLIQDDLQRSDSRVPLLGDIPGV 571
Cdd:PRK10560 281 TPTVLQKGRIRLKLH--ISQNVPGQVLQqADGEVLAIDKQEIETQVEVKSGETLALGGIFSRKNKSGQDSVPLLGDIPWL 358

                        330       340
                 ....*....|....*....|....*
gi 489197383 572 GRLFRSSRETRVKRNLMVFLRPSIV 596
Cdd:PRK10560 359 GQLFRHDGKEDERRELVVFITPRLV 383
PRK15346 PRK15346
EscC/YscC/HrcC family type III secretion system outer membrane ring protein;
320-578 4.25e-13

EscC/YscC/HrcC family type III secretion system outer membrane ring protein;


Pssm-ID: 237950 [Multi-domain]  Cd Length: 499  Bit Score: 72.42  E-value: 4.25e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383 320 ADESLNALVILADPEDVGLLEDIVRQLDVPRAQLLVEAAIVEL-SGEIgDALGVQWA----LRSGHVAGGAGFADSGLS- 393
Cdd:PRK15346 240 ADPRQNAVIVRDRAANMAIYRSLITQLDQRPQMIEISVSIIDVdAGDI-NQLGIDWSasasLGGGKISFNSGFADGNASg 318

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383 394 IGTLLGalqagkppaelpdgaivglGSRDFGALVTALSRNSRSNLLSTPSLLTLDNQKAeiLVGQNVPFqtgsYTtSASG 473
Cdd:PRK15346 319 FSTVIS-------------------NTGNFMVRLNALEKNSKAKILSQPSVVTLNNIQA--VLDKNVTF----YT-KLQG 372

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383 474 SSNPftTVERKDIGVTLKVTPHIGEDR-----MLRLEIE--QEISSIAPTATLAAkavdlVTNKR-SIKSTVLAddGQVI 545
Cdd:PRK15346 373 EKVA--KLESITTGSLLRVTPRLIDDNgtqkvMLNLNIQdgQQSATQSETDPLPE-----VQNSEiATQATLKA--GQSL 443

                        250       260       270
                 ....*....|....*....|....*....|...
gi 489197383 546 VLGGLIQDDLQRSDSRVPLLGDIPGVGRLFRSS 578
Cdd:PRK15346 444 LLGGFIQDKQIESQNKIPLLGDIPLIGGLFRST 476
Secretin_N pfam03958
Bacterial type II/III secretion system short domain; This is a short, often repeated, domain ...
 276-352 2.66e-10

Bacterial type II/III secretion system short domain; This is a short, often repeated, domain found in bacterial type II/III secretory system proteins. All previous NolW-like domains fall into this family.


Pssm-ID: 461109 [Multi-domain]  Cd Length: 68  Bit Score: 56.84  E-value: 2.66e-10
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489197383  276 SRVIRLRHGDAKTLAATLGEIGEslhGERGQDGRGSgkrgllVRADESLNALVILADPEDVGLLEDIVRQLDVPRAQ 352
Cdd:pfam03958   1 TRVIPLKYASAEDLASALRSLLG---GSGLLSKRGS------VVADPRTNSLIVSGPPEYVELVRQLIKQLDVPRAQ 68
PRK15339 PRK15339
EscC/YscC/HrcC family type III secretion system outer membrane ring protein;
261-591 7.06e-10

EscC/YscC/HrcC family type III secretion system outer membrane ring protein;


Pssm-ID: 237948 [Multi-domain]  Cd Length: 559  Bit Score: 62.48  E-value: 7.06e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383 261 RLAQSLDVPSSRSANSRVIRLrhgdaKTLAATlGEIGESLHGERGQDGRGSGKRGLL-----VRADESLNALVILADPED 335
Cdd:PRK15339 212 RLLNGEEQPSGRQASSEPPAM-----PPFSAN-GEKGKAANYAGGMSLQEALKQNAAagdikIIAYPDTNSLLVKGTAEQ 285

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383 336 VGLLEDIVRQLDVPRAQLLVEAAIVELSGEIGDALGVQWalrSGhvaggagfadsGLSIGTLLGAlqagkppaELPDGAI 415
Cdd:PRK15339 286 VHFIEMLVKALDVAKRHVELSLWIIDLDKSDLEQLGVNW---SG-----------SITIGDKLGV--------SLNQSSI 343

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383 416 VGLGSRDFGALVTALSRNSRSNLLStpslltldnqKAEILVGQNVP--FQTG-SYTTSASGSSNpfTTVERKDIGVTLKV 492
Cdd:PRK15339 344 STLDGSRFIAAVMALEQKKKANVVS----------RPVVLTQENIPaiFDNNrTFYTKLVGERN--VALEHVTYGTMISV 411

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489197383 493 TPHIGED----RMLRLEIEQEISSIAPTATlaaKAVDLVTNKRSIKSTVL-ADDGQVIVLGGLIQDDLQRSDSRVPLLGD 567
Cdd:PRK15339 412 LPRFSADgqieMSLDIEDGNEKTPQSDTTT---SVDALPEVGRTLISTIArVPQGKSLLIGGYTRDANTDEVQSIPFLGS 488

                        330       340
                 ....*....|....*....|....*.
gi 489197383 568 IPGVGRLFR--SSRETRVKRnlmVFL 591
Cdd:PRK15339 489 LPLIGSLFRysSKNKSNIVR---VFL 511
Secretin_N pfam03958
Bacterial type II/III secretion system short domain; This is a short, often repeated, domain ...
 206-272 9.08e-09

Bacterial type II/III secretion system short domain; This is a short, often repeated, domain found in bacterial type II/III secretory system proteins. All previous NolW-like domains fall into this family.


Pssm-ID: 461109 [Multi-domain]  Cd Length: 68  Bit Score: 52.60  E-value: 9.08e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489197383  206 IYDMRHAWVAEIAEVLdRSVTPAAGKSAATVQVLADSRSNRLVLLGPPQARARLLRLAQSLDVPSSR 272
Cdd:pfam03958   3 VIPLKYASAEDLASAL-RSLLGGSGLLSKRGSVVADPRTNSLIVSGPPEYVELVRQLIKQLDVPRAQ 68
Secretin_N pfam03958
Bacterial type II/III secretion system short domain; This is a short, often repeated, domain ...
 141-201 1.39e-07

Bacterial type II/III secretion system short domain; This is a short, often repeated, domain found in bacterial type II/III secretory system proteins. All previous NolW-like domains fall into this family.


Pssm-ID: 461109 [Multi-domain]  Cd Length: 68  Bit Score: 49.14  E-value: 1.39e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489197383  141 TRVVQAQQTSVAELIPMIRPLVPAH------GHLAAVPSANALIVSDRRSNIERIEAIVRSLDRAGE 201
Cdd:pfam03958   1 TRVIPLKYASAEDLASALRSLLGGSgllskrGSVVADPRTNSLIVSGPPEYVELVRQLIKQLDVPRA 67
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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