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Conserved domains on  [gi|489179359|ref|WP_003088853|]
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MULTISPECIES: ParB/RepB/Spo0J family partition protein [Pseudomonas]

Protein Classification

IbrB-like domain-containing protein( domain architecture ID 11611634)

IbrB-like domain-containing protein, a member of the ParB/Srx superfamily; similar to Escherichia coli IbrB which along with IbrA activates immunoglobulin-binding eib genes

CATH:  1.10.10.2830
Gene Ontology:  GO:0071453|GO:0003677
PubMed:  25358815

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
IbrB_like cd16397
immunoglobulin-binding regulator IbrB activates eib genes; IbrB (along with IbrA) activates ...
 47-149 5.42e-54

immunoglobulin-binding regulator IbrB activates eib genes; IbrB (along with IbrA) activates immunoglobulin-binding eib genes in Escherichia coli. IbrB is related to the ParB N-terminal domain family, which includes DNA-binding proteins involved in chromosomal/plasmid segregation and transcriptional regulation, consistent with a possible mechanism for IbrB in DNA binding-related regulation of eib expression. The ParB like family is a diverse domain superfamily with structural and sequence similarity to ParB of bacterial chromosomes/plasmid parABS partitioning system and Sulfiredoxin (Srx), which is a reactivator of oxidatively inactivated 2-cys peroxiredoxins. Other families includes proteins related to StrR, a putative regulator in the biosynthetic gene cluster and a family containing a Pyrococcus furiosus nuclease and putative transcriptional regulators SbnI (Staphylococcus aureus siderophore biosynthetic gene cluster ) and EdeB (Brevibacillus brevis antimicrobial peptide edeine biosynthetic cluster). Nuclease activity has also been reported in arabidopsis Srx.


:

Pssm-ID: 319255 [Multi-domain]  Cd Length: 100  Bit Score: 167.75  E-value: 5.42e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489179359  47 PVDCVQWVRAERVAGNDYNPNTVAPPEMRLLRLSIESDGFTQPIVAYPQA-DGRYEVVDGFHRLRVGSAKgALRQRLHGY 125
Cdd:cd16397    1 PVDNVQWVPIEKVQANDYNPNKVAPPEMKLLKLSILEDGFTQPIVVYYDEeDDKYVIVDGFHRYTLAKKK-PLIERLKGY 79

                         90       100
                 ....*....|....*....|....
gi 489179359 126 LPIAAIRAGREgdsERIAATIRHN 149
Cdd:cd16397   80 LPVVVLDKDLE---ERMASTIRHN 100
 
Name Accession Description Interval E-value
IbrB_like cd16397
immunoglobulin-binding regulator IbrB activates eib genes; IbrB (along with IbrA) activates ...
 47-149 5.42e-54

immunoglobulin-binding regulator IbrB activates eib genes; IbrB (along with IbrA) activates immunoglobulin-binding eib genes in Escherichia coli. IbrB is related to the ParB N-terminal domain family, which includes DNA-binding proteins involved in chromosomal/plasmid segregation and transcriptional regulation, consistent with a possible mechanism for IbrB in DNA binding-related regulation of eib expression. The ParB like family is a diverse domain superfamily with structural and sequence similarity to ParB of bacterial chromosomes/plasmid parABS partitioning system and Sulfiredoxin (Srx), which is a reactivator of oxidatively inactivated 2-cys peroxiredoxins. Other families includes proteins related to StrR, a putative regulator in the biosynthetic gene cluster and a family containing a Pyrococcus furiosus nuclease and putative transcriptional regulators SbnI (Staphylococcus aureus siderophore biosynthetic gene cluster ) and EdeB (Brevibacillus brevis antimicrobial peptide edeine biosynthetic cluster). Nuclease activity has also been reported in arabidopsis Srx.


Pssm-ID: 319255 [Multi-domain]  Cd Length: 100  Bit Score: 167.75  E-value: 5.42e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489179359  47 PVDCVQWVRAERVAGNDYNPNTVAPPEMRLLRLSIESDGFTQPIVAYPQA-DGRYEVVDGFHRLRVGSAKgALRQRLHGY 125
Cdd:cd16397    1 PVDNVQWVPIEKVQANDYNPNKVAPPEMKLLKLSILEDGFTQPIVVYYDEeDDKYVIVDGFHRYTLAKKK-PLIERLKGY 79

                         90       100
                 ....*....|....*....|....
gi 489179359 126 LPIAAIRAGREgdsERIAATIRHN 149
Cdd:cd16397   80 LPVVVLDKDLE---ERMASTIRHN 100
ParBc pfam02195
ParB/Sulfiredoxin domain; Proteins containing this domain include Escherichia coli plasmid ...
 52-150 1.62e-12

ParB/Sulfiredoxin domain; Proteins containing this domain include Escherichia coli plasmid protein ParB and mammalian Sulfiredoxin-1. ParB is involved in chromosome partition. It localizes to both poles of the predivisional cell following completion of DNA replication. Sulfiredoxin-1 contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4.


Pssm-ID: 426651 [Multi-domain]  Cd Length: 90  Bit Score: 60.76  E-value: 1.62e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489179359   52 QWVRAERVAGNDYNPNTVAPPEMRLLRLSIESDGFTQPIVAYPQADGRYEVVDGFHRLRvgSAKGAlrqrlhGYLPIAAI 131
Cdd:pfam02195   1 EEVPISKLRPNPDQPRKDSEESLEELAASIKKRGLLQPIIVRKTPDGRYEIIAGERRLR--AAKLL------GLKEVPVI 72

                          90
                  ....*....|....*....
gi 489179359  132 rAGREGDSERIAATIRHNR 150
Cdd:pfam02195  73 -VREIDDEEAIALSLIENI 90
Spo0J COG1475
Chromosome segregation protein Spo0J, contains ParB-like nuclease domain [Cell cycle control, ...
 51-205 4.11e-11

Chromosome segregation protein Spo0J, contains ParB-like nuclease domain [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441084 [Multi-domain]  Cd Length: 241  Bit Score: 60.39  E-value: 4.11e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489179359  51 VQWVRAERVAGNDYNPNTVAPPE-MRLLRLSIESDGFTQPIVAYPQADGRYEVVDGFHRLRvgsakgalrqrlhgylpiA 129
Cdd:COG1475    7 IREIPIDKIVPSPYNPRRTFDEEaLEELAASIREHGLLQPILVRPLGDGRYEIIAGERRLR------------------A 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489179359 130 AIRAGRE---------GDSERIAATIRHNRARGvhgvlPMTAI-----VVTLL-KAGWSEADVARELGMDNDEVLRFKQV 194
Cdd:COG1475   69 AKLLGLEtvpaivrdlDDEEALELALIENLQRE-----DLNPLeearaYQRLLeEFGLTQEEIAERLGKSRSEVSNLLRL 143

                        170
                 ....*....|.
gi 489179359 195 SGLPELFREHV 205
Cdd:COG1475  144 LKLPPEVQEAL 154
ParB smart00470
ParB-like nuclease domain; Plasmid RK2 ParB preferentially cleaves single-stranded DNA. ParB ...
 53-150 4.24e-09

ParB-like nuclease domain; Plasmid RK2 ParB preferentially cleaves single-stranded DNA. ParB also nicks supercoiled plasmid DNA preferably at sites with potential single-stranded character, like AT-rich regions and sequences that can form cruciform structures. ParB also exhibits 5-->3 exonuclease activity.


Pssm-ID: 214678 [Multi-domain]  Cd Length: 89  Bit Score: 51.92  E-value: 4.24e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489179359    53 WVRAERVAGNDYNPNTVAPPEMRLLRLSIESDGFTQPIVAYPqADGRYEVVDGFHRLRvgsakgALRQRLHGYLPiAAIR 132
Cdd:smart00470   2 EVPIEKLRPNPDQPRLTSEESLEELAESIKENGLLQPIIVRP-NDGRYEIIDGERRLR------AAKLLGLKEVP-VIVR 73

                           90
                   ....*....|....*...
gi 489179359   133 AGreGDSERIAATIRHNR 150
Cdd:smart00470  74 DL--DDEEAIALSLEENI 89
PRK13866 PRK13866
plasmid partitioning protein RepB; Provisional
 72-199 5.16e-04

plasmid partitioning protein RepB; Provisional


Pssm-ID: 172387 [Multi-domain]  Cd Length: 336  Bit Score: 39.94  E-value: 5.16e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489179359  72 PEMRLLRLSIESDGFTQPIVA--YPQADGRYEVVDGFHRLRvgsAKGALRQrlhgylPIAAIrAGREGDSERIAATIRHN 149
Cdd:PRK13866  88 PKFEQLEASISQEGQQVPILVrpHPEAAGRYQIVYGRRRLR---AAVNLRR------EVSAI-VRNLTDRELVVAQGREN 157

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 489179359 150 RARGVHGVLPMTAIVVTLLKAGWSEADVARELGMDNDEVLRFKQVS-GLPE 199
Cdd:PRK13866 158 LDRADLSFIEKALFALRLEDAGFDRATIIAALSTDKADLSRYITVArGIPL 208
 
Name Accession Description Interval E-value
IbrB_like cd16397
immunoglobulin-binding regulator IbrB activates eib genes; IbrB (along with IbrA) activates ...
 47-149 5.42e-54

immunoglobulin-binding regulator IbrB activates eib genes; IbrB (along with IbrA) activates immunoglobulin-binding eib genes in Escherichia coli. IbrB is related to the ParB N-terminal domain family, which includes DNA-binding proteins involved in chromosomal/plasmid segregation and transcriptional regulation, consistent with a possible mechanism for IbrB in DNA binding-related regulation of eib expression. The ParB like family is a diverse domain superfamily with structural and sequence similarity to ParB of bacterial chromosomes/plasmid parABS partitioning system and Sulfiredoxin (Srx), which is a reactivator of oxidatively inactivated 2-cys peroxiredoxins. Other families includes proteins related to StrR, a putative regulator in the biosynthetic gene cluster and a family containing a Pyrococcus furiosus nuclease and putative transcriptional regulators SbnI (Staphylococcus aureus siderophore biosynthetic gene cluster ) and EdeB (Brevibacillus brevis antimicrobial peptide edeine biosynthetic cluster). Nuclease activity has also been reported in arabidopsis Srx.


Pssm-ID: 319255 [Multi-domain]  Cd Length: 100  Bit Score: 167.75  E-value: 5.42e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489179359  47 PVDCVQWVRAERVAGNDYNPNTVAPPEMRLLRLSIESDGFTQPIVAYPQA-DGRYEVVDGFHRLRVGSAKgALRQRLHGY 125
Cdd:cd16397    1 PVDNVQWVPIEKVQANDYNPNKVAPPEMKLLKLSILEDGFTQPIVVYYDEeDDKYVIVDGFHRYTLAKKK-PLIERLKGY 79

                         90       100
                 ....*....|....*....|....
gi 489179359 126 LPIAAIRAGREgdsERIAATIRHN 149
Cdd:cd16397   80 LPVVVLDKDLE---ERMASTIRHN 100
ParBc pfam02195
ParB/Sulfiredoxin domain; Proteins containing this domain include Escherichia coli plasmid ...
 52-150 1.62e-12

ParB/Sulfiredoxin domain; Proteins containing this domain include Escherichia coli plasmid protein ParB and mammalian Sulfiredoxin-1. ParB is involved in chromosome partition. It localizes to both poles of the predivisional cell following completion of DNA replication. Sulfiredoxin-1 contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4.


Pssm-ID: 426651 [Multi-domain]  Cd Length: 90  Bit Score: 60.76  E-value: 1.62e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489179359   52 QWVRAERVAGNDYNPNTVAPPEMRLLRLSIESDGFTQPIVAYPQADGRYEVVDGFHRLRvgSAKGAlrqrlhGYLPIAAI 131
Cdd:pfam02195   1 EEVPISKLRPNPDQPRKDSEESLEELAASIKKRGLLQPIIVRKTPDGRYEIIAGERRLR--AAKLL------GLKEVPVI 72

                          90
                  ....*....|....*....
gi 489179359  132 rAGREGDSERIAATIRHNR 150
Cdd:pfam02195  73 -VREIDDEEAIALSLIENI 90
Spo0J COG1475
Chromosome segregation protein Spo0J, contains ParB-like nuclease domain [Cell cycle control, ...
 51-205 4.11e-11

Chromosome segregation protein Spo0J, contains ParB-like nuclease domain [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441084 [Multi-domain]  Cd Length: 241  Bit Score: 60.39  E-value: 4.11e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489179359  51 VQWVRAERVAGNDYNPNTVAPPE-MRLLRLSIESDGFTQPIVAYPQADGRYEVVDGFHRLRvgsakgalrqrlhgylpiA 129
Cdd:COG1475    7 IREIPIDKIVPSPYNPRRTFDEEaLEELAASIREHGLLQPILVRPLGDGRYEIIAGERRLR------------------A 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489179359 130 AIRAGRE---------GDSERIAATIRHNRARGvhgvlPMTAI-----VVTLL-KAGWSEADVARELGMDNDEVLRFKQV 194
Cdd:COG1475   69 AKLLGLEtvpaivrdlDDEEALELALIENLQRE-----DLNPLeearaYQRLLeEFGLTQEEIAERLGKSRSEVSNLLRL 143

                        170
                 ....*....|.
gi 489179359 195 SGLPELFREHV 205
Cdd:COG1475  144 LKLPPEVQEAL 154
ParB smart00470
ParB-like nuclease domain; Plasmid RK2 ParB preferentially cleaves single-stranded DNA. ParB ...
 53-150 4.24e-09

ParB-like nuclease domain; Plasmid RK2 ParB preferentially cleaves single-stranded DNA. ParB also nicks supercoiled plasmid DNA preferably at sites with potential single-stranded character, like AT-rich regions and sequences that can form cruciform structures. ParB also exhibits 5-->3 exonuclease activity.


Pssm-ID: 214678 [Multi-domain]  Cd Length: 89  Bit Score: 51.92  E-value: 4.24e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489179359    53 WVRAERVAGNDYNPNTVAPPEMRLLRLSIESDGFTQPIVAYPqADGRYEVVDGFHRLRvgsakgALRQRLHGYLPiAAIR 132
Cdd:smart00470   2 EVPIEKLRPNPDQPRLTSEESLEELAESIKENGLLQPIIVRP-NDGRYEIIDGERRLR------AAKLLGLKEVP-VIVR 73

                           90
                   ....*....|....*...
gi 489179359   133 AGreGDSERIAATIRHNR 150
Cdd:smart00470  74 DL--DDEEAIALSLEENI 89
ParB_N_Srx cd16387
ParB N-terminal domain and sulfiredoxin protein-related families; The ParB N-terminal domain ...
 71-110 2.27e-07

ParB N-terminal domain and sulfiredoxin protein-related families; The ParB N-terminal domain/Sulfiredoxin (Srx) superfamily contains proteins with diverse activities. Many of the families are involved in segregation and competition between plasmids and chromosomes. Several families share similar activities with the N-terminal domain of ParB (Spo0J in Bacillus subtilis), a DNA-binding component of the prokaryotic parABS partitioning system. Also within this superfamily is sulfiredoxin (Srx; reactivator of oxidatively inactivated 2-cys peroxiredoxins), RepB N-terminal domain (plasmid segregation replication protein B like protein), nucleoid occlusion protein, KorB N-terminal domain partition protein of low copy number plasmid RK2, irbB (immunoglobulin-binding regulator that activates eib genes), N-terminal domain of sopB protein (promotes proper partitioning of F1 plasmid), fertility inhibition factors OSA and FiwA,DNA sulfur modification protein DndB, and a ParB-like toxin domain. Other activities includes a StrR (regulator in the streptomycin biosynthetic gene cluster), and a family containing a Pyrococcus furiosus nuclease and putative transcriptional regulators sbnI (Staphylococcus aureus siderophore biosynthetic gene cluster ). Nuclease activity has also been reported in Arabidopsis Srx.


Pssm-ID: 319246 [Multi-domain]  Cd Length: 54  Bit Score: 46.04  E-value: 2.27e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 489179359  71 PPEMRLLRLSIESDGFTQPIVAYPQADGRYEVVDGFHRLR 110
Cdd:cd16387    2 EEELEELAESIREHGVLQPIIVRPLPDGRYEIIAGERRWR 41
PRK13866 PRK13866
plasmid partitioning protein RepB; Provisional
 72-199 5.16e-04

plasmid partitioning protein RepB; Provisional


Pssm-ID: 172387 [Multi-domain]  Cd Length: 336  Bit Score: 39.94  E-value: 5.16e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489179359  72 PEMRLLRLSIESDGFTQPIVA--YPQADGRYEVVDGFHRLRvgsAKGALRQrlhgylPIAAIrAGREGDSERIAATIRHN 149
Cdd:PRK13866  88 PKFEQLEASISQEGQQVPILVrpHPEAAGRYQIVYGRRRLR---AAVNLRR------EVSAI-VRNLTDRELVVAQGREN 157

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 489179359 150 RARGVHGVLPMTAIVVTLLKAGWSEADVARELGMDNDEVLRFKQVS-GLPE 199
Cdd:PRK13866 158 LDRADLSFIEKALFALRLEDAGFDRATIIAALSTDKADLSRYITVArGIPL 208
ParB_N_like cd16407
ParB N-terminal, parA-binding, -like domain of bacterial and plasmid parABS partitioning ...
 72-115 5.85e-04

ParB N-terminal, parA-binding, -like domain of bacterial and plasmid parABS partitioning systems; This family represents the N-terminal domain of ParB, a DNA-binding component of the prokaryotic parABS partitioning system. parABS contributes to the efficient segregation of chromosomes and low-copy number plasmids to daughter cells during prokaryotic cell division. The process includes the parA (Walker box) ATPase, the ParB DNA-binding protein and a parS cis-acting DNA sites. Binding of ParB to centromere-like parS sites is followed by non-specific binding to DNA ("spreading", which has been implicated in gene silencing in plasmid P1) and oligomerization of additional ParB molecules near the parS sites. It has been proposed that ParB-ParB cross-linking compacts the DNA, binds to parA via the N-terminal region, and leads to parA separating the ParB-parS complexes and the recruitment of the SMC (structural maintenance of chromosomes) complexes. The ParB N-terminal domain of Bacillus subtilis and other species contains a Arginine-rich ParB Box II with residues essential for bridging of the ParB-parS complexes. The arginine-rich ParB Box II consensus (I[VIL]AGERR[FYW]RA[AS] identified in several species is partially conserved with this family and related families. Mutations within the basic columns particularly debilitate spreading from the parS sites and impair SMC recruitment. The C-terminal domain contains a HTH DNA-binding motif and is the primary homo-dimerization domain, and binds to parS DNA sites. Additional homo-dimerization contacts are found along the N-terminal domain, but dimerization of the N-terminus may only occur after concentration at ParB-parS foci.


Pssm-ID: 319264 [Multi-domain]  Cd Length: 86  Bit Score: 37.50  E-value: 5.85e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 489179359  72 PEMRLLRLSIESDGFTQPIVAYPQADGRYEVVDGfHRlRVGSAK 115
Cdd:cd16407   18 EEMEELVESIKENGVLTPIIVRPREDGGYEIISG-HR-RKRACE 59
SPO0J_N cd16393
Thermus thermophilus stage 0 sporulation protein J-like N-terminal domain, ParB family member; ...
 80-110 3.02e-03

Thermus thermophilus stage 0 sporulation protein J-like N-terminal domain, ParB family member; Spo0J (stage 0 sporulation protein J) is a ParB family member, a critical component of the ParABS-type bacterial chromosome segregation system. The Spo0J N-terminal region acts in protein-protein interaction and is adjacent to the DNA-binding domain that binds to parS sites. Two Spo0J bind per parS site, and Spo0J interacts with neighbors via the N-terminal domain to form oligomers via an Arginine-rich patch (RRXR). This superfamily represents the N-terminal domain of ParB, a DNA-binding component of the prokaryotic parABS partitioning system. parABS contributes to the efficient segregation of chromosomes and low-copy number plasmids to daughter cells during prokaryotic cell division. The process includes the parA (Walker box) ATPase, the ParB DNA-binding protein and a parS cis-acting DNA sites. Binding of ParB to centromere-like parS sites is followed by non-specific binding to DNA ("spreading", which has been implicated in gene silencing in plasmid P1) and oligomerization of additional ParB molecules near the parS sites. It has been proposed that ParB-ParB cross-linking compacts the DNA, binds to parA via the N-terminal region, and leads to parA separating the ParB-parS complexes and the recruitment of the SMC (structural maintenance of chromosomes) complexes. The ParB N-terminal domain of Bacillus subtilis and other species contains a Arginine-rich ParB Box II with residues essential for bridging of the ParB-parS complexes. The arginine-rich ParB Box II consensus (I[VIL]AGERR[FYW]RA[AS] identified in several species is partially conserved with this family and related families. Mutations within the basic columns particularly debilitate spreading from the parS sites and impair SMC recruitment. The C-terminal domain contains a HTH DNA-binding motif and is the primary homo-dimerization domain, and binds to parS DNA sites. Additional homo-dimerization contacts are found along the N-terminal domain, but dimerization of the N-terminus may only occur after concentration at ParB-parS foci.


Pssm-ID: 319251 [Multi-domain]  Cd Length: 97  Bit Score: 35.92  E-value: 3.02e-03
                         10        20        30
                 ....*....|....*....|....*....|.
gi 489179359  80 SIESDGFTQPIVAYPQADGRYEVVDGFHRLR 110
Cdd:cd16393   31 SIKEHGLLQPIVVRKVGDGRYEIIAGERRWR 61
Noc_N cd16396
nucleoid occlusion protein, N-terminal domain, and related domains of the ParB partitioning ...
 62-110 4.87e-03

nucleoid occlusion protein, N-terminal domain, and related domains of the ParB partitioning protein family; Nucleoid occlusion protein has been shown in Bacillus subtilis to bind to specific DNA sequences on the chromosome (Noc-binding DNA sequences, NBS), inhibiting cell division near the nucleoid and thereby protecting the chromosome. This N-terminal domain is related to the N-terminal domain of ParB/repB partitioning system proteins.


Pssm-ID: 319254 [Multi-domain]  Cd Length: 95  Bit Score: 35.28  E-value: 4.87e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 489179359  62 NDYNPNTVAPPEMRL-LRLSIESDGFTQPIVAYPQADGRYEVVDGFHRLR 110
Cdd:cd16396   14 NPYQPRKEFDEEEIEeLAESIKEHGLLQPIVVRKTKDGGYEIVAGERRWR 63
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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