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Conserved domains on  [gi|489146391|ref|WP_003056137|]
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MULTISPECIES: TrbC/VirB2 family protein [Pseudomonadota]

Protein Classification

TrbC/VirB2 family protein( domain architecture ID 10008057)

TrbC/VirB2 family protein may function a major pilus subunit; similar to type IV secretion system protein PtlA, which is a component of the type IV secretion system ptl required for secretion of assembled pertussis toxin (PTX) through the outer membrane

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
VirB2 COG3838
Type IV secretory pathway, VirB2 component (pilin) [Intracellular trafficking, secretion, and ...
 47-108 5.23e-17

Type IV secretory pathway, VirB2 component (pilin) [Intracellular trafficking, secretion, and vesicular transport];


:

Pssm-ID: 443049  Cd Length: 109  Bit Score: 70.75  E-value: 5.23e-17
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489146391  47 AQAAGSSMPWEGPLQSILESIQGPVARIVAVIIIIATGLALAFGDTSGGFRKLIQIVFGLSI 108
Cdd:COG3838   28 AFAAGSGMPWEGPLQQIVNSLTGPVAKAIAVIAIIVAGLMLAFGELNGGFRRAIQVVLGISI 89
 
Name Accession Description Interval E-value
VirB2 COG3838
Type IV secretory pathway, VirB2 component (pilin) [Intracellular trafficking, secretion, and ...
 47-108 5.23e-17

Type IV secretory pathway, VirB2 component (pilin) [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443049  Cd Length: 109  Bit Score: 70.75  E-value: 5.23e-17
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489146391  47 AQAAGSSMPWEGPLQSILESIQGPVARIVAVIIIIATGLALAFGDTSGGFRKLIQIVFGLSI 108
Cdd:COG3838   28 AFAAGSGMPWEGPLQQIVNSLTGPVAKAIAVIAIIVAGLMLAFGELNGGFRRAIQVVLGISI 89
TrbC pfam04956
TrbC/VIRB2 pilin; TrbC is a pilin found in bacterial type IV secretion systems. The protein ...
 47-108 3.76e-07

TrbC/VIRB2 pilin; TrbC is a pilin found in bacterial type IV secretion systems. The protein undergoes three processing steps before gaining its mature cyclic structure. This family also contains VIRB2 type IV secretion proteins. This alignment contains two predicted transmembrane helices.


Pssm-ID: 398559  Cd Length: 98  Bit Score: 44.90  E-value: 3.76e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489146391   47 AQAAGSSMPWEGPLQSILESIQGPVARIVAVIIIIATGLALAFGDTSggFRKLIQIVFGLSI 108
Cdd:pfam04956  28 AFAQGSGDPVETALQNIVDSLTGPIARVIATIAIIIAGIMLAFGRLS--WRTLVYVVIGIVI 87
 
Name Accession Description Interval E-value
VirB2 COG3838
Type IV secretory pathway, VirB2 component (pilin) [Intracellular trafficking, secretion, and ...
 47-108 5.23e-17

Type IV secretory pathway, VirB2 component (pilin) [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443049  Cd Length: 109  Bit Score: 70.75  E-value: 5.23e-17
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489146391  47 AQAAGSSMPWEGPLQSILESIQGPVARIVAVIIIIATGLALAFGDTSGGFRKLIQIVFGLSI 108
Cdd:COG3838   28 AFAAGSGMPWEGPLQQIVNSLTGPVAKAIAVIAIIVAGLMLAFGELNGGFRRAIQVVLGISI 89
TrbC pfam04956
TrbC/VIRB2 pilin; TrbC is a pilin found in bacterial type IV secretion systems. The protein ...
 47-108 3.76e-07

TrbC/VIRB2 pilin; TrbC is a pilin found in bacterial type IV secretion systems. The protein undergoes three processing steps before gaining its mature cyclic structure. This family also contains VIRB2 type IV secretion proteins. This alignment contains two predicted transmembrane helices.


Pssm-ID: 398559  Cd Length: 98  Bit Score: 44.90  E-value: 3.76e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489146391   47 AQAAGSSMPWEGPLQSILESIQGPVARIVAVIIIIATGLALAFGDTSggFRKLIQIVFGLSI 108
Cdd:pfam04956  28 AFAQGSGDPVETALQNIVDSLTGPIARVIATIAIIIAGIMLAFGRLS--WRTLVYVVIGIVI 87
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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