MULTISPECIES: recombinase family protein [Bacteria]
recombinase family protein( domain architecture ID 10132964)
recombinase family protein is a serine recombinase that catalyzes the site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme
List of domain hits
Name | Accession | Description | Interval | E-value | |||
SR_ResInv | cd03768 | Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members ... |
3-132 | 4.82e-50 | |||
Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. Resolvases and invertases affect resolution or inversion and comprise a major phylogenic group. Resolvases (e.g. Tn3, gamma-delta, and Tn5044) normally recombine two sites in direct repeat causing deletion of the DNA between the sites. Invertases (e.g. Gin and Hin) recombine sites in inverted repeat to invert the DNA between the sites. Cointegrate resolution with gamma-delta resolvase requires the formation of a synaptosome of three resolvase dimers bound to each of two res sites on the DNA. Also included in this subfamily are some putative integrases including a sequence from bacteriophage phi-FC1. : Pssm-ID: 239737 [Multi-domain] Cd Length: 126 Bit Score: 157.64 E-value: 4.82e-50
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Name | Accession | Description | Interval | E-value | ||||
SR_ResInv | cd03768 | Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members ... |
3-132 | 4.82e-50 | ||||
Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. Resolvases and invertases affect resolution or inversion and comprise a major phylogenic group. Resolvases (e.g. Tn3, gamma-delta, and Tn5044) normally recombine two sites in direct repeat causing deletion of the DNA between the sites. Invertases (e.g. Gin and Hin) recombine sites in inverted repeat to invert the DNA between the sites. Cointegrate resolution with gamma-delta resolvase requires the formation of a synaptosome of three resolvase dimers bound to each of two res sites on the DNA. Also included in this subfamily are some putative integrases including a sequence from bacteriophage phi-FC1. Pssm-ID: 239737 [Multi-domain] Cd Length: 126 Bit Score: 157.64 E-value: 4.82e-50
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SpoIVCA | COG1961 | Site-specific DNA recombinase SpoIVCA/DNA invertase PinE [Replication, recombination and ... |
1-166 | 6.47e-45 | ||||
Site-specific DNA recombinase SpoIVCA/DNA invertase PinE [Replication, recombination and repair]; Pssm-ID: 441564 [Multi-domain] Cd Length: 388 Bit Score: 152.49 E-value: 6.47e-45
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Resolvase | pfam00239 | Resolvase, N terminal domain; The N-terminal domain of the resolvase family (this family) ... |
3-142 | 2.02e-41 | ||||
Resolvase, N terminal domain; The N-terminal domain of the resolvase family (this family) contains the active site and the dimer interface. The extended arm at the C-terminus of this domain connects to the C-terminal helix-turn-helix domain of resolvase - see pfam02796. Pssm-ID: 425548 [Multi-domain] Cd Length: 144 Bit Score: 136.63 E-value: 2.02e-41
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Resolvase | smart00857 | Resolvase, N terminal domain; The N-terminal domain of the resolvase family contains the ... |
3-142 | 2.50e-39 | ||||
Resolvase, N terminal domain; The N-terminal domain of the resolvase family contains the active site and the dimer interface. The extended arm at the C-terminus of this domain connects to the C-terminal helix-turn-helix domain of resolvase. Pssm-ID: 214861 [Multi-domain] Cd Length: 148 Bit Score: 131.21 E-value: 2.50e-39
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mpi | PRK13413 | master DNA invertase Mpi family serine-type recombinase; |
1-153 | 6.41e-14 | ||||
master DNA invertase Mpi family serine-type recombinase; Pssm-ID: 184041 [Multi-domain] Cd Length: 200 Bit Score: 67.05 E-value: 6.41e-14
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Name | Accession | Description | Interval | E-value | ||||
SR_ResInv | cd03768 | Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members ... |
3-132 | 4.82e-50 | ||||
Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. Resolvases and invertases affect resolution or inversion and comprise a major phylogenic group. Resolvases (e.g. Tn3, gamma-delta, and Tn5044) normally recombine two sites in direct repeat causing deletion of the DNA between the sites. Invertases (e.g. Gin and Hin) recombine sites in inverted repeat to invert the DNA between the sites. Cointegrate resolution with gamma-delta resolvase requires the formation of a synaptosome of three resolvase dimers bound to each of two res sites on the DNA. Also included in this subfamily are some putative integrases including a sequence from bacteriophage phi-FC1. Pssm-ID: 239737 [Multi-domain] Cd Length: 126 Bit Score: 157.64 E-value: 4.82e-50
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SpoIVCA | COG1961 | Site-specific DNA recombinase SpoIVCA/DNA invertase PinE [Replication, recombination and ... |
1-166 | 6.47e-45 | ||||
Site-specific DNA recombinase SpoIVCA/DNA invertase PinE [Replication, recombination and repair]; Pssm-ID: 441564 [Multi-domain] Cd Length: 388 Bit Score: 152.49 E-value: 6.47e-45
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Resolvase | pfam00239 | Resolvase, N terminal domain; The N-terminal domain of the resolvase family (this family) ... |
3-142 | 2.02e-41 | ||||
Resolvase, N terminal domain; The N-terminal domain of the resolvase family (this family) contains the active site and the dimer interface. The extended arm at the C-terminus of this domain connects to the C-terminal helix-turn-helix domain of resolvase - see pfam02796. Pssm-ID: 425548 [Multi-domain] Cd Length: 144 Bit Score: 136.63 E-value: 2.02e-41
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Resolvase | smart00857 | Resolvase, N terminal domain; The N-terminal domain of the resolvase family contains the ... |
3-142 | 2.50e-39 | ||||
Resolvase, N terminal domain; The N-terminal domain of the resolvase family contains the active site and the dimer interface. The extended arm at the C-terminus of this domain connects to the C-terminal helix-turn-helix domain of resolvase. Pssm-ID: 214861 [Multi-domain] Cd Length: 148 Bit Score: 131.21 E-value: 2.50e-39
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Ser_Recombinase | cd00338 | Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or ... |
4-132 | 2.20e-23 | ||||
Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and serine recombinase. Serine recombinases demonstrate functional versatility and include resolvases, invertases, integrases, and transposases. Resolvases and invertases (i.e. Tn3, gamma-delta, Tn5044 resolvases, Gin and Hin invertases) in this family contain a C-terminal DNA binding domain and comprise a major phylogenic group. Also included are phage- and bacterial-encoded recombinases such as phiC31 integrase, SpoIVCA excisionase, and Tn4451 TnpX transposase. These integrases and transposases have larger C-terminal domains compared to resolvases/invertases and are referred to as large serine recombinases. Also belonging to this family are proteins with N-terminal DNA binding domains similar to IS607- and IS1535-transposases from Helicobacter and Mycobacterium. Pssm-ID: 238206 [Multi-domain] Cd Length: 137 Bit Score: 90.01 E-value: 2.20e-23
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mpi | PRK13413 | master DNA invertase Mpi family serine-type recombinase; |
1-153 | 6.41e-14 | ||||
master DNA invertase Mpi family serine-type recombinase; Pssm-ID: 184041 [Multi-domain] Cd Length: 200 Bit Score: 67.05 E-value: 6.41e-14
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SR_Res_par | cd03767 | Serine recombinase (SR) family, Partitioning (par)-Resolvase subfamily, catalytic domain; ... |
3-132 | 5.43e-13 | ||||
Serine recombinase (SR) family, Partitioning (par)-Resolvase subfamily, catalytic domain; Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. This subgroup is composed of proteins similar to the E. coli resolvase found in the par region of the RP4 plasmid, which encodes a highly efficient partitioning system. This protein is part of a complex stabilization system involved in the resolution of plasmid dimers during cell division. Similar to Tn3 and other resolvases, members of this family may contain a C-terminal DNA binding domain. Pssm-ID: 239736 [Multi-domain] Cd Length: 146 Bit Score: 63.11 E-value: 5.43e-13
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SR_IS607_transposase_like | cd03769 | Serine Recombinase (SR) family, IS607-like transposase subfamily, catalytic domain; members ... |
3-70 | 1.35e-04 | ||||
Serine Recombinase (SR) family, IS607-like transposase subfamily, catalytic domain; members contain a DNA binding domain with homology to MerR/SoxR located N-terminal to the catalytic domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. This subfamily is composed of proteins that catalyze the transposition of insertion sequence (IS) elements such as IS607 from Helicobacter and IS1535 from Mycobacterium, and similar proteins from other bacteria and several archaeal species. IS elements are DNA segments that move to new sites in prokaryotic and eukaryotic genomes causing insertion mutations and gene rearrangements. Pssm-ID: 239738 Cd Length: 134 Bit Score: 39.94 E-value: 1.35e-04
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Blast search parameters | ||||
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