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Conserved domains on  [gi|485945797|ref|WP_001493762|]
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MULTISPECIES: recombinase family protein [Bacteria]

Protein Classification

recombinase family protein( domain architecture ID 10132964)

recombinase family protein is a serine recombinase that catalyzes the site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
SR_ResInv cd03768
Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members ...
3-132 4.82e-50

Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. Resolvases and invertases affect resolution or inversion and comprise a major phylogenic group. Resolvases (e.g. Tn3, gamma-delta, and Tn5044) normally recombine two sites in direct repeat causing deletion of the DNA between the sites. Invertases (e.g. Gin and Hin) recombine sites in inverted repeat to invert the DNA between the sites. Cointegrate resolution with gamma-delta resolvase requires the formation of a synaptosome of three resolvase dimers bound to each of two res sites on the DNA. Also included in this subfamily are some putative integrases including a sequence from bacteriophage phi-FC1.


:

Pssm-ID: 239737 [Multi-domain]  Cd Length: 126  Bit Score: 157.64  E-value: 4.82e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485945797   3 YAYIRVSSADQNTARQEEALSKAGfQPDKICVEHASAKDTNRPGLQELLGQLRPGDTLLVHSIDRLCRNMSDMCAVTTRL 82
Cdd:cd03768    2 IGYARVSTDDQSLERQLEALKAAG-ECDKIFEEKGSGGKKERPELQKLLEDLREGDTLVVTKLDRLGRSTKDLLEIVEEL 80
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 485945797  83 RDQGVTLIFLKEQLTfsagTNNPMQELQLHMMSAFSQFERALLKERQADG 132
Cdd:cd03768   81 REKGVSLRSLTEGID----TSTPSGKLMLTILGAFAEFERELIRERTKEG 126
 
Name Accession Description Interval E-value
SR_ResInv cd03768
Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members ...
3-132 4.82e-50

Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. Resolvases and invertases affect resolution or inversion and comprise a major phylogenic group. Resolvases (e.g. Tn3, gamma-delta, and Tn5044) normally recombine two sites in direct repeat causing deletion of the DNA between the sites. Invertases (e.g. Gin and Hin) recombine sites in inverted repeat to invert the DNA between the sites. Cointegrate resolution with gamma-delta resolvase requires the formation of a synaptosome of three resolvase dimers bound to each of two res sites on the DNA. Also included in this subfamily are some putative integrases including a sequence from bacteriophage phi-FC1.


Pssm-ID: 239737 [Multi-domain]  Cd Length: 126  Bit Score: 157.64  E-value: 4.82e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485945797   3 YAYIRVSSADQNTARQEEALSKAGfQPDKICVEHASAKDTNRPGLQELLGQLRPGDTLLVHSIDRLCRNMSDMCAVTTRL 82
Cdd:cd03768    2 IGYARVSTDDQSLERQLEALKAAG-ECDKIFEEKGSGGKKERPELQKLLEDLREGDTLVVTKLDRLGRSTKDLLEIVEEL 80
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 485945797  83 RDQGVTLIFLKEQLTfsagTNNPMQELQLHMMSAFSQFERALLKERQADG 132
Cdd:cd03768   81 REKGVSLRSLTEGID----TSTPSGKLMLTILGAFAEFERELIRERTKEG 126
SpoIVCA COG1961
Site-specific DNA recombinase SpoIVCA/DNA invertase PinE [Replication, recombination and ...
1-166 6.47e-45

Site-specific DNA recombinase SpoIVCA/DNA invertase PinE [Replication, recombination and repair];


Pssm-ID: 441564 [Multi-domain]  Cd Length: 388  Bit Score: 152.49  E-value: 6.47e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485945797   1 MQYAYIRVSSADQ---NTARQEEAL----SKAGFQPDKICVEHA-SAKDTNRPGLQELLGQLRPG--DTLLVHSIDRLCR 70
Cdd:COG1961    3 RAAGYARVSTDDQeglSLERQREALrayaEKAGWEIVRIYVDEGvSGTSKDRPGLQRLLADLRAGkfDTLVVWKLDRLGR 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485945797  71 NMSDMCAVTTRLRDQGVTLIFLKEQLTfsagTNNPMQELQLHMMSAFSQFERALLKERQADGIAAKKARGEKTGRP--GA 148
Cdd:COG1961   83 NLADLLELVEELKERGVRLISLTEGID----TSTPMGRLLLTILAAFAEFERELISERTRAGLAAAKARGKYLGRPpyGY 158
                        170
                 ....*....|....*...
gi 485945797 149 DIKKIQEIDALRSRGVRL 166
Cdd:COG1961  159 RDPKKLVIDEEEAEVVRR 176
Resolvase pfam00239
Resolvase, N terminal domain; The N-terminal domain of the resolvase family (this family) ...
3-142 2.02e-41

Resolvase, N terminal domain; The N-terminal domain of the resolvase family (this family) contains the active site and the dimer interface. The extended arm at the C-terminus of this domain connects to the C-terminal helix-turn-helix domain of resolvase - see pfam02796.


Pssm-ID: 425548 [Multi-domain]  Cd Length: 144  Bit Score: 136.63  E-value: 2.02e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485945797    3 YAYIRVSSADQN--TARQEEALSKAGFQPDKICV---EHASAKDTNRPGLQELLGQLRP--GDTLLVHSIDRLCRNMSDM 75
Cdd:pfam00239   2 IGYARVSTEDQDdsLERQLEALRAYAACNGKIVEfedKGVSGRKLDRPGLQRLLALLRAgkGDVLVVYKLDRLGRSLRDL 81
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 485945797   76 CAVTTRLRDQGVTLIFLKEQLTfsagTNNPMQELQLHMMSAFSQFERALLKERQADGIAAKKARGEK 142
Cdd:pfam00239  82 LTLVEELREKGVDLVSLDEGID----TSTPMGRLLLTILAALAEFERALIRERTRAGLAAAAARGKL 144
Resolvase smart00857
Resolvase, N terminal domain; The N-terminal domain of the resolvase family contains the ...
3-142 2.50e-39

Resolvase, N terminal domain; The N-terminal domain of the resolvase family contains the active site and the dimer interface. The extended arm at the C-terminus of this domain connects to the C-terminal helix-turn-helix domain of resolvase.


Pssm-ID: 214861 [Multi-domain]  Cd Length: 148  Bit Score: 131.21  E-value: 2.50e-39
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485945797     3 YAYIRVSSADQ---NTARQEEALSKA----GFQPDKICVEHA-SAKDTNRPGLQELLGQLRPGD--TLLVHSIDRLCRNM 72
Cdd:smart00857   2 AGYARVSTDDQadgSLERQLEALRAYaernGWEVVRIYEDEGvSGKKADRPGLQRLLADLRAGDidVLVVYKLDRLGRSL 81
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485945797    73 SDMCAVTTRLRDQGVTLIFLKEQLTFsagTNNPMQELQLHMMSAFSQFERALLKERQADGIAAKKARGEK 142
Cdd:smart00857  82 RDLLALLELLEEKGVRLVSLKEGILD---TSTPAGRLLLDILAALAEFERELISERTKAGLARAAARGRW 148
mpi PRK13413
master DNA invertase Mpi family serine-type recombinase;
1-153 6.41e-14

master DNA invertase Mpi family serine-type recombinase;


Pssm-ID: 184041 [Multi-domain]  Cd Length: 200  Bit Score: 67.05  E-value: 6.41e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485945797   1 MQYAYIRVSSADQNTARQEEALS----KAGFQPDKICVEHASA-KDTNRPGLQELLGQLRPGDTLLVHSIDRLCRNMSDM 75
Cdd:PRK13413   1 MIYAYIRVSTDKQTVENQRFEITnfaeKNNLTIDKWIEETISGtKSYKDRKLGKLLKKMRKGDILIVSELSRLGRNLMEI 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485945797  76 CAVTTRLRDQGVTLIFLKEQLTFSAGTNNPMqelqlhMMSAFS---QFERALLKERQADGIAAKKARGEKTGRPGADIKK 152
Cdd:PRK13413  81 MSILNICMEKEVIVYTIKEGYELGDDINSKV------LAFAFGlsaEIERNLISQRTKEALARKKAEGVTLGRPKGSTPK 154

                 .
gi 485945797 153 I 153
Cdd:PRK13413 155 K 155
 
Name Accession Description Interval E-value
SR_ResInv cd03768
Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members ...
3-132 4.82e-50

Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. Resolvases and invertases affect resolution or inversion and comprise a major phylogenic group. Resolvases (e.g. Tn3, gamma-delta, and Tn5044) normally recombine two sites in direct repeat causing deletion of the DNA between the sites. Invertases (e.g. Gin and Hin) recombine sites in inverted repeat to invert the DNA between the sites. Cointegrate resolution with gamma-delta resolvase requires the formation of a synaptosome of three resolvase dimers bound to each of two res sites on the DNA. Also included in this subfamily are some putative integrases including a sequence from bacteriophage phi-FC1.


Pssm-ID: 239737 [Multi-domain]  Cd Length: 126  Bit Score: 157.64  E-value: 4.82e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485945797   3 YAYIRVSSADQNTARQEEALSKAGfQPDKICVEHASAKDTNRPGLQELLGQLRPGDTLLVHSIDRLCRNMSDMCAVTTRL 82
Cdd:cd03768    2 IGYARVSTDDQSLERQLEALKAAG-ECDKIFEEKGSGGKKERPELQKLLEDLREGDTLVVTKLDRLGRSTKDLLEIVEEL 80
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 485945797  83 RDQGVTLIFLKEQLTfsagTNNPMQELQLHMMSAFSQFERALLKERQADG 132
Cdd:cd03768   81 REKGVSLRSLTEGID----TSTPSGKLMLTILGAFAEFERELIRERTKEG 126
SpoIVCA COG1961
Site-specific DNA recombinase SpoIVCA/DNA invertase PinE [Replication, recombination and ...
1-166 6.47e-45

Site-specific DNA recombinase SpoIVCA/DNA invertase PinE [Replication, recombination and repair];


Pssm-ID: 441564 [Multi-domain]  Cd Length: 388  Bit Score: 152.49  E-value: 6.47e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485945797   1 MQYAYIRVSSADQ---NTARQEEAL----SKAGFQPDKICVEHA-SAKDTNRPGLQELLGQLRPG--DTLLVHSIDRLCR 70
Cdd:COG1961    3 RAAGYARVSTDDQeglSLERQREALrayaEKAGWEIVRIYVDEGvSGTSKDRPGLQRLLADLRAGkfDTLVVWKLDRLGR 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485945797  71 NMSDMCAVTTRLRDQGVTLIFLKEQLTfsagTNNPMQELQLHMMSAFSQFERALLKERQADGIAAKKARGEKTGRP--GA 148
Cdd:COG1961   83 NLADLLELVEELKERGVRLISLTEGID----TSTPMGRLLLTILAAFAEFERELISERTRAGLAAAKARGKYLGRPpyGY 158
                        170
                 ....*....|....*...
gi 485945797 149 DIKKIQEIDALRSRGVRL 166
Cdd:COG1961  159 RDPKKLVIDEEEAEVVRR 176
Resolvase pfam00239
Resolvase, N terminal domain; The N-terminal domain of the resolvase family (this family) ...
3-142 2.02e-41

Resolvase, N terminal domain; The N-terminal domain of the resolvase family (this family) contains the active site and the dimer interface. The extended arm at the C-terminus of this domain connects to the C-terminal helix-turn-helix domain of resolvase - see pfam02796.


Pssm-ID: 425548 [Multi-domain]  Cd Length: 144  Bit Score: 136.63  E-value: 2.02e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485945797    3 YAYIRVSSADQN--TARQEEALSKAGFQPDKICV---EHASAKDTNRPGLQELLGQLRP--GDTLLVHSIDRLCRNMSDM 75
Cdd:pfam00239   2 IGYARVSTEDQDdsLERQLEALRAYAACNGKIVEfedKGVSGRKLDRPGLQRLLALLRAgkGDVLVVYKLDRLGRSLRDL 81
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 485945797   76 CAVTTRLRDQGVTLIFLKEQLTfsagTNNPMQELQLHMMSAFSQFERALLKERQADGIAAKKARGEK 142
Cdd:pfam00239  82 LTLVEELREKGVDLVSLDEGID----TSTPMGRLLLTILAALAEFERALIRERTRAGLAAAAARGKL 144
Resolvase smart00857
Resolvase, N terminal domain; The N-terminal domain of the resolvase family contains the ...
3-142 2.50e-39

Resolvase, N terminal domain; The N-terminal domain of the resolvase family contains the active site and the dimer interface. The extended arm at the C-terminus of this domain connects to the C-terminal helix-turn-helix domain of resolvase.


Pssm-ID: 214861 [Multi-domain]  Cd Length: 148  Bit Score: 131.21  E-value: 2.50e-39
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485945797     3 YAYIRVSSADQ---NTARQEEALSKA----GFQPDKICVEHA-SAKDTNRPGLQELLGQLRPGD--TLLVHSIDRLCRNM 72
Cdd:smart00857   2 AGYARVSTDDQadgSLERQLEALRAYaernGWEVVRIYEDEGvSGKKADRPGLQRLLADLRAGDidVLVVYKLDRLGRSL 81
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485945797    73 SDMCAVTTRLRDQGVTLIFLKEQLTFsagTNNPMQELQLHMMSAFSQFERALLKERQADGIAAKKARGEK 142
Cdd:smart00857  82 RDLLALLELLEEKGVRLVSLKEGILD---TSTPAGRLLLDILAALAEFERELISERTKAGLARAAARGRW 148
Ser_Recombinase cd00338
Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or ...
4-132 2.20e-23

Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and serine recombinase. Serine recombinases demonstrate functional versatility and include resolvases, invertases, integrases, and transposases. Resolvases and invertases (i.e. Tn3, gamma-delta, Tn5044 resolvases, Gin and Hin invertases) in this family contain a C-terminal DNA binding domain and comprise a major phylogenic group. Also included are phage- and bacterial-encoded recombinases such as phiC31 integrase, SpoIVCA excisionase, and Tn4451 TnpX transposase. These integrases and transposases have larger C-terminal domains compared to resolvases/invertases and are referred to as large serine recombinases. Also belonging to this family are proteins with N-terminal DNA binding domains similar to IS607- and IS1535-transposases from Helicobacter and Mycobacterium.


Pssm-ID: 238206 [Multi-domain]  Cd Length: 137  Bit Score: 90.01  E-value: 2.20e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485945797   4 AYIRVSSADQN----TARQEEALSKA----GFQPDKICVEHAS--AKDTNRPGLQELLG--QLRPGDTLLVHSIDRLCRN 71
Cdd:cd00338    1 IYARVSTDKQEqgdsLERQREALREYaarnGLEVVGEYEDAGSsaTSLVDRPGLQRLLAdvKAGKIDVVLVEKLDRLSRN 80
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 485945797  72 MSDMCAVTTRLRDQGVTLIFLKEQLTfsagTNNPMQELQLHMMSAFSQFERALLKERQADG 132
Cdd:cd00338   81 LVDLLELLELLEAHGVRVVTADGEID----LDSEDGRLMLGILAAMAEEESKLISERTKRG 137
mpi PRK13413
master DNA invertase Mpi family serine-type recombinase;
1-153 6.41e-14

master DNA invertase Mpi family serine-type recombinase;


Pssm-ID: 184041 [Multi-domain]  Cd Length: 200  Bit Score: 67.05  E-value: 6.41e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485945797   1 MQYAYIRVSSADQNTARQEEALS----KAGFQPDKICVEHASA-KDTNRPGLQELLGQLRPGDTLLVHSIDRLCRNMSDM 75
Cdd:PRK13413   1 MIYAYIRVSTDKQTVENQRFEITnfaeKNNLTIDKWIEETISGtKSYKDRKLGKLLKKMRKGDILIVSELSRLGRNLMEI 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485945797  76 CAVTTRLRDQGVTLIFLKEQLTFSAGTNNPMqelqlhMMSAFS---QFERALLKERQADGIAAKKARGEKTGRPGADIKK 152
Cdd:PRK13413  81 MSILNICMEKEVIVYTIKEGYELGDDINSKV------LAFAFGlsaEIERNLISQRTKEALARKKAEGVTLGRPKGSTPK 154

                 .
gi 485945797 153 I 153
Cdd:PRK13413 155 K 155
SR_Res_par cd03767
Serine recombinase (SR) family, Partitioning (par)-Resolvase subfamily, catalytic domain; ...
3-132 5.43e-13

Serine recombinase (SR) family, Partitioning (par)-Resolvase subfamily, catalytic domain; Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. This subgroup is composed of proteins similar to the E. coli resolvase found in the par region of the RP4 plasmid, which encodes a highly efficient partitioning system. This protein is part of a complex stabilization system involved in the resolution of plasmid dimers during cell division. Similar to Tn3 and other resolvases, members of this family may contain a C-terminal DNA binding domain.


Pssm-ID: 239736 [Multi-domain]  Cd Length: 146  Bit Score: 63.11  E-value: 5.43e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485945797   3 YAYIRVSSADQNTARQEEALSK----AGFQPDKICVEHASAKDTNRPGLQELLGQLRPGDTLLVHSIDRLCR-NMSDMCA 77
Cdd:cd03767    2 RAYLRASTDEQDATRAKESLEAfateRGFYIAGFYVENASGAKLDRPELFRLLDDAQSGDVLLVEQIDRLSRlPLDDWET 81
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 485945797  78 VTTRLRDQGVTLIFLKEQLTFSAGTNNP----------MQELQLHMMSAFSQFERALLKERQADG 132
Cdd:cd03767   82 LKASIAAKGLRVVSLDLPTSHSALAAEDndftgrilsaINDMLLDLLAAMARKDYEDRRERQKQG 146
SR_IS607_transposase_like cd03769
Serine Recombinase (SR) family, IS607-like transposase subfamily, catalytic domain; members ...
3-70 1.35e-04

Serine Recombinase (SR) family, IS607-like transposase subfamily, catalytic domain; members contain a DNA binding domain with homology to MerR/SoxR located N-terminal to the catalytic domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. This subfamily is composed of proteins that catalyze the transposition of insertion sequence (IS) elements such as IS607 from Helicobacter and IS1535 from Mycobacterium, and similar proteins from other bacteria and several archaeal species. IS elements are DNA segments that move to new sites in prokaryotic and eukaryotic genomes causing insertion mutations and gene rearrangements.


Pssm-ID: 239738  Cd Length: 134  Bit Score: 39.94  E-value: 1.35e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 485945797   3 YAYIRVSSADQ--NTARQEEAL---SKAGFQPDKICVEHASAKDTNRPGLQELLGQLRPG--DTLLVHSIDRLCR 70
Cdd:cd03769    2 VLYARVSSHDQkdDLERQIERLeayATAQGWIVEVIKDIGSGLNEKRKGLLKLLEDVLAGkvERVVITYKDRLAR 76
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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