|
Name |
Accession |
Description |
Interval |
E-value |
| PRK09752 |
PRK09752 |
AIDA-I family autotransporter YfaL; |
1-1244 |
0e+00 |
|
AIDA-I family autotransporter YfaL;
Pssm-ID: 182059 [Multi-domain] Cd Length: 1250 Bit Score: 2196.77 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 1 MRIIFLRKEYLSLLPSMIASLFSANGFAAAIDLCQGYDIKASCHASRQSLSGITQDWSVADGQWLVFSDMTNNASGGAVF 80
Cdd:PRK09752 1 MRIIFLRKEYLSLLPSMIASLFSANGVAAVIDSCQGYDIKASCQASRQSLSGITQDWSIADGQWLVFSDMTNNASGGAVF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 81 LQQGAEFSLLPENETGMTLFANNTVTGEYNNGGAIFAKENSTLNLTDVIFSGNVAGGYGGAIYSSGTNDTGAVDLRVTNA 160
Cdd:PRK09752 81 LQQGAEFTLSPENETGMTLFANNTVSGEYNNGGAIFAKENSTLNLTDVIFSGNVAGGYGGAIYSSGTNDTGAVDLRVTNA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 161 MFRNNIANDGKGGAIYTINNDVYLSDVIFDNNQAYTSTSYSDGDGGAIDVTDNNSVSKHPSGYTIINNTAFTNNTAEGYG 240
Cdd:PRK09752 161 MFRNNIANDGKGGAIYTINNDVYLSDVIFDNNQAYTSTSYSDGDGGAIDVTDNNSDSKHPSGYTIINNTAFTNNTAEGYG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 241 GAIYTNSATAPYLIDISVDDSYSQNGGVLVDENNSAAGYGDGPSTAAGGFMYLGLSEVTFDIADGKTLVIGNTENDGAVD 320
Cdd:PRK09752 241 GAIYTNSATAPYLIDISVDDSYSQNGGVLVDENNSAAGYGDGPSSAAGGFMYLGLSEVTFDIADGKTLVIGNTENDGAVD 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 321 SIAGTGLITKTGSGDLVLNADNNDFTGEMQIENGEVTLGRSNSLMNVGDTHCQDDPQDCYGLTIGSIDKYQNQAELNVGS 400
Cdd:PRK09752 321 SIAGTGLITKTGSGDLVLNADNNDFTGEMQIENGEVTLGRSNSLMNVGDTHCQDDPQDCYGLTIGSIDKYQNQAELNVGS 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 401 TQQTFVHSLTGFQNGTLNIDAGGNVTVNQGSFAGTIEGAGQLTIAQNGSYVLSGAQSMALTGDIVVDDGAVLSLEGDAAD 480
Cdd:PRK09752 401 TQQTFVHSLTGFQNGTLNIDAGGNVTVNQGSFAGTIEGAGQLTIAQNGSYVLAGAQSMALTGDIVVDDGAVLSLEGDAAD 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 481 LAALQDDPQSIVLNGGVLDLSDFSTWQSGTSYNDGLEVSGSSGTVIGSQDVVDLAGGDNLHIGGDGKDGVYVVVDASDGQ 560
Cdd:PRK09752 481 LRALQDDPQSIVLNGGVLDLSDFSTWQSGTSYNDGLEVSGSSGTVIGSQDVVDLAGGDDLHIGGDGKDGVYVVIDAGDGQ 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 561 VSLANNNSYLGTTQIASGTLMVSDNSQLGDTHYNRQVIFTDKQQESVMEITANVDTRSTTTEHGRDIEMRADGEVAVDAG 640
Cdd:PRK09752 561 VSLANNNSYLGTTQIASGTLMVSDNSQLGDTHYNRQVIFTDKQQESVMEITADVDTRSTTTGHGRDIEMRADGEVAVDAG 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 641 VDTQWGALMADSSGQHQDEGSTLTKTGAGTLELTASGTTQSAVRVEEGTLKGDVADIFPYASSLWVGDGATFVTGADQDI 720
Cdd:PRK09752 641 VDTQWGALMADSSGQHQDEGSTLTKTGAGTLELTASGTTQSAVRVEEGTLKGDVADIIPYASSLWVGDGATFVTGADQDI 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 721 QSIDATSSGTIDISDGTVLRLTGQDTSVALNASLFNGDGTLVNATDGVTLTGELNTNLETDSLTYLSDVTVNGNLTNTSG 800
Cdd:PRK09752 721 QSIDATSSGTIDISDGTVLRLTGQDTSVALNASLFNGDGTLVNATDGVTLTGELNTNLETDSLTYLSDVTVNGNLTNTSG 800
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 801 AVSLQNGVAGDTLTVNGDYTGGGTLLLDSELNGDDSVSDQLVLNGNTAGNTTVVVNSITGIGEPTSTGIKVVDFAADPTQ 880
Cdd:PRK09752 801 AVSLQNGVAGDTLTVNGDYTGGGTLLLDSELNGDDSVSDQLVLNGNTAGNTTVVVNSITGIGEPTSTGIKVVDFAADPTQ 880
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 881 FQNNAKFSLAGSGYVNMGAYDYTLVEDNNDWYLRSQEVTPPLPPD----PDPDPTPDPDPTPD--PIPAYQPVLNAKVGG 954
Cdd:PRK09752 881 FQNNAQFSLAGSGYVNMGAYDYTLVEDNNDWYLRSQEVTPPSPPDpdptPDPDPTPDPDPTPDpePTPAYQPVLNAKVGG 960
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 955 YLNNLRAANQAFMMERRDHAGGNGQTLNLRVIGGRYHYTAAGQLAQHEDTSTVQLSGDLFSGRWGDDGEWMLGAVGGYSD 1034
Cdd:PRK09752 961 YLNNLRAANQAFMMERRDHAGGDGQTLNLRVIGGDYHYTAAGQLAQHEDTSTVQLSGDLFSGRWGDDGEWMLGIVGGYSD 1040
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 1035 NQGESRSNMTGTRADNQNHGYAVGLTSSWYQHGNQKQGAWLDSWLQYAWFNNDVSEQDDGTDHYHSSGIIASLEAGYQWL 1114
Cdd:PRK09752 1041 NQGDSRSNMTGTRADNQNHGYAVGLTSSWFQHGNQKQGAWLDSWLQYAWFNNDVSEQEDGTDHYHSSGIIASLEAGYQWL 1120
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 1115 PGRGVVIEPQAQVIYQGVQQDDFTAANRARVSQSQGDDIQMRLGLHSEWRTAVHVIPTLDLNYYHNPHSTEIEEDGSTIS 1194
Cdd:PRK09752 1121 PGRGVVIEPQAQVIYQGVQQDDFTAANHARVSQSQGDDIQTRLGLHSEWRTAVHVIPTLDLNYYHDPHSTEIEEDGSTIS 1200
|
1210 1220 1230 1240 1250
....*....|....*....|....*....|....*....|....*....|
gi 485781081 1195 DDAVKQRGEIKVGVTGNISQRVSLRGSVAWQKGSDDFAQMAGFLSMTVKW 1244
Cdd:PRK09752 1201 DDAVKQRGEIKVGVTGNISQRVSLRGSVAWQKGSDDFAQTAGFLSMTVKW 1250
|
|
| autotrans_barl |
TIGR01414 |
outer membrane autotransporter barrel domain; A number of Gram-negative bacterial proteins, ... |
806-1244 |
3.08e-89 |
|
outer membrane autotransporter barrel domain; A number of Gram-negative bacterial proteins, mostly found in pathogens and associated with virulence, contain a conserved C-terminal domain that integrates into the outer membrane and enables the N-terminal region to be delivered across the membrane. This C-terminal autotransporter domain is about 400 amino acids in length and includes the aromatic amino acid-rich OMP signal, typically ending with a Phe or Trp residue, at the extreme C-terminus. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]
Pssm-ID: 273608 [Multi-domain] Cd Length: 431 Bit Score: 295.45 E-value: 3.08e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 806 NGVAGDTLTVNGDYTGGGTLLLDSELNGDDSVSDQLVLNGNTAGNTTVVVNSITGIGEPTSTGIKVVDfaadpTQFQNNA 885
Cdd:TIGR01414 1 PGGAFNTLTVNGLYTGNGGFVMNTDLGGDNSQTDRLVVNGNASGTTGVVVNNIGGEGAQTGDGITLVT-----VNGGSDA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 886 KFSLAGsGYVNMGAYDYTLV----EDNNDWYLRSQEvtpplPPDPDPDPTPDPDPTPDPIPAYQPVLNAKVGGYLNNLRA 961
Cdd:TIGR01414 76 AFTLAN-GKVDAGAYTYTLYkngtEDNNNWYLTSSL-----PDLTPPGQQLSPTYRAEAGSYAANANAALFLAELDTLRQ 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 962 ANQAFMMERRDhaggNGQTLNLRVIGGRYHYTA-AGQLAQHEDTSTVQLSGDLFSGRWGdDGEWMLGAVGGYSDNQGESR 1040
Cdd:TIGR01414 150 RMGDLRSAARD----AGNGVWARIFGGDNHLDGdAGAAGYDQNTTGVQLGGDILLAGNA-DGDLHVGLMAGYAKADIKTR 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 1041 SNMTGtrADNQNHGYAVGLTSSWYQHGnqkqGAWLDSWLQYAWFNNDVSEQDDG---TDHYHSSGIIASLEAGYQWLPG- 1116
Cdd:TIGR01414 225 SYKYG--GKGKVDGYGLGLYGTWLQDS----GAYVDGVLQYSRFRNDVSSTGSNgkvSGKYNSNGFTASLEAGYRYNLGg 298
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 1117 RGVVIEPQAQVIYQGVQQDDFTAANRARVSQSQGDDIQMRLGLHSEWR----TAVHVIPTLDLNYYHNPH-STEIEEDGS 1191
Cdd:TIGR01414 299 NGWYVEPQAQLSYFGVSGDDYKESNGTRVLGGGGDSLQGRLGLRVGYQfdlgTGRAVKPYLKANVLHEFKgGTGVRVNGV 378
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 485781081 1192 TISDDAVKQRGEIKVGVTGNISQRVSLRGSVAWQKGSDDFAQMAGFLSMTVKW 1244
Cdd:TIGR01414 379 TIRNDFSGTRAEYGVGVNAKIKDNLSLYADVDYQKGGKKYTDNQGNLGVRYSF 431
|
|
| AidA |
COG3468 |
Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular ... |
410-1231 |
2.32e-80 |
|
Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442691 [Multi-domain] Cd Length: 846 Bit Score: 282.61 E-value: 2.32e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 410 TGFQNGTLNIDAGGNVTVNQGSFAGTIEGAGQLTIAQNGSYVLSGAQSMALTGDIVVDDGAVLSLEGDAADLAALQDDPQ 489
Cdd:COG3468 1 TASGGGGGATGLGGGGTGGGGGLGGTGGGNAGLGIGNGGGGGAASGSGAGGVAGNGGGGGGGAGGGGGGAGSGGGLAGAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 490 SIVLNGGVLDLSDFSTWQSGTSYNDGLEVSGSSGTVIGSQDVVDLAGGDNLHIGGDGKDGVYVVVDASDGQVSLANNNSY 569
Cdd:COG3468 81 SGGTGGNSTGGGGGNSGTGGTGGGGGGGGSGNGGGGGGGGGGGGTGGGGGGGTGSAGGGGGGGGGGTGVGGTGAAAAGGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 570 LGTTQIASGTLMVSDNSQLGDTHYNRQVIFTDKQQESVMEITANVDTRSTTTEHGRDIEMRADGEVAVDAGVDTQWGALM 649
Cdd:COG3468 161 TGSGGGGSGGGGGAGGGGGGGAGGSGGAGSTGSGAGGGGGGSGGGGGAAGTGGGGGGGGGAGGATGGAGSGGNTGGGVGG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 650 ADSSGQHQDEGSTLTKTGAGTLELTASGTTQSAVRVEEGTLKGDVADIFPYASSLWVGDGATFVTGADQDIQSIDATSSG 729
Cdd:COG3468 241 GGGSAGGTGGGGLTGGGAAGTGGGGGGTGTGSGGGGGGGANGGGSGGGGGASGTGGGGTASTGGGGGGGGGNGGGGGGGS 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 730 TIDISDGTVLRLTGQDTSVALNASLFNGDGTLVNATDGVTLTGELNTNLETDSLTYLSDVTVNGNLTNTSGAVSLQNGV- 808
Cdd:COG3468 321 NAGGGSGGGGGGGGGGGGGGTTLNGAGSAGGGTGAALAGTGGSGSGGGGGGGSGGGGGAGGGGANTGSDGVGTGLTTGGt 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 809 ------------------AGDTLTVNGDYTG-GGTLLLDSELNGDDSVSDQLVLNGNTAGNTTVVVNSITGIGEPTSTGI 869
Cdd:COG3468 401 gnnggggvgggggggltlTGGTLTVNGNYTGnNGTLVLNTVLGDDNSPTDRLVVNGNTSGTTGVRVNNAGGLGAQTVNGI 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 870 KVVDfaadpTQFQNNAKFSLagSGYVNMGAYDYTLV-----EDNNDWYLRSQEVTPPLPpdpdpdptpdpdptpdpipay 944
Cdd:COG3468 481 EVVE-----VNGASDGAFTL--GGRVVAGAYEYTLYqggsgGDDGNWYLRSTLTPPDPP--------------------- 532
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 945 QPVLNAKVGGYLNNLRAANQAFMMER----------RDHAGGNGQTLNLRVIGGRYHY-TAAGQLAQHEDTSTVQLSGDL 1013
Cdd:COG3468 533 TPVYRPEVPSYLANPAAANGLFELGTlhdrlgerryTDTGESDNSGAWLRVEGGHNRSrDSSGQLDYDSNRYGLQLGGDL 612
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 1014 FSGRwGDDGEWMLGAVGGYSDNQGESRSNMTGTrADNQNHGYAVGLTSSWYQHgnqkQGAWLDSWLQYAWFNNDVSEQDD 1093
Cdd:COG3468 613 LQWE-DGGGRLHVGVMAGYGNGDSDVRSRATGT-GKGDVDGYSLGLYGTWYGN----NGFYVDGVLQYSWFDNDVSSDDL 686
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 1094 G--TDHYHSSGIIASLEAGYQWLPGRGVVIEPQAQVIYQGVQQDDFTAANRARVSQSQGDDIQMRLGLH----SEWRTAV 1167
Cdd:COG3468 687 GgvTGSYDGNGYSASLEAGYPFKLGEGWSLEPQAQLIYQGVDFDDFTDSNGTRVSGDDGDSLQGRLGLRlgyeFHWDDGR 766
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 485781081 1168 HVIPTLDLNYYHNP-HSTEIEEDGSTISDDAVKQRGEIKVGVTGNISQRVSLRGSVAWQKGSDDF 1231
Cdd:COG3468 767 ALQPYLEANWLHEFlGDNSVTVNGVSFSQDGSGTWGELGLGVTGQLNKNLSLYGDVGYQTGLDGY 831
|
|
| auto_AIDA-I |
NF033176 |
autotransporter adhesin AIDA-I; |
747-1244 |
1.19e-35 |
|
autotransporter adhesin AIDA-I;
Pssm-ID: 380183 [Multi-domain] Cd Length: 1287 Bit Score: 147.88 E-value: 1.19e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 747 SVALNASLFNGDGTLVNATDGVTLTGELNT-------------NLETDS-LTY----LSDVTVNGNLTNTSGAV-SLQNG 807
Cdd:NF033176 767 SAVVNADMAVSQNAYINISDQATINGSVNNkgsvvinnsiingNITNDAdLSFgtakLLSATVNGSLVNNKNIIlNPTKE 846
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 808 VAGDTLTVNgDYTG--GGTLLLDSELNGDDSVSDQLVLNGNTAGNTTVVVNSITGIGEPTSTGIKVVDFAADptqfqNNA 885
Cdd:NF033176 847 SAGNTLTVS-NYTGtpGSVISLGGVLEGDNSLTDRLVVKGNTSGQSDIVYVNEGGSGGQTIEGINIISVEGN-----SDA 920
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 886 KFSLAGSgyVNMGAYDYTLVE------DNNDWYLRSQevtpplppdpdpdptpdpdPTPDPIPAYQPvlnaKVGGYLNNL 959
Cdd:NF033176 921 EFSLKNR--VVAGAYDYTLQKgnvsgtDKKGWYLTSH-------------------LPTSDTRQYRP----ENGSYATNM 975
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 960 RAANQAFMM---ERRDHAGGNGQT------LNLRVIGGRyhytAAGQLAQHEDTSTV-----QLSGDLFSGRWGDDGEWM 1025
Cdd:NF033176 976 ALANSLFLMdlnERKQFSAVNDNTqpesasVWMKITGGR----TSGKLSDGQNKTTTnqfinQLGGDIYKYHAEKLGDFT 1051
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 1026 LGAVGGYSDNQGESRSNMTGTRADNQNHGYAVGLTSSWYQHGNQKQGAWLDSWLQYAWFNNDVSEQDDGTDHYHSSGIIA 1105
Cdd:NF033176 1052 LGIMGGYANAKGKTINHTSKKGARNTLDGYSAGLYGTWYQNGANATGLFAETWMQYNWFNASVKGDGLEEEKYNLNGLTA 1131
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 1106 SLEAGYQ-----WLPGRGVV----IEPQAQVIYQGVQQDDFTAANRARVSQSQGDDIQMRLGLHSEWR--------TAVH 1168
Cdd:NF033176 1132 SVGGGYNlnvhtWTSPEGIKgefwLQPHLQAVWMGVTPDTHQEDNGTVVQGTGKNNLQTKAGIRASWKvkssldkdTGRE 1211
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 485781081 1169 VIPTLDLNYYHNPHSTEIEEDGSTISDDAVKQRGEIKVGVTGNISQRVSLRGSVAWQKGSDDFAQMAGFLSMTVKW 1244
Cdd:NF033176 1212 FRPYIEANWIHNTHEFGVKMSGDNQLLSGSRNQGEIKTGIEGVITQNLSVNGGVAYQAGGHGSNAISGALGIKYSF 1287
|
|
| PL2_Passenger_AT |
cd01344 |
Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of ... |
729-916 |
2.38e-33 |
|
Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43, AIDA-1 and IcsA, as well as, the less characterized ShdA, MisL, and BapA autotransporters.
Pssm-ID: 238654 [Multi-domain] Cd Length: 188 Bit Score: 127.42 E-value: 2.38e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 729 GTIDISDGTVL--RLTGQDTSVALNASLFnGDGTLVNATDG-VTLTGELNTNLETDSltylsdVTVNGNLTNtSGAVSLQ 805
Cdd:cd01344 1 GTITGNGGWKLggDLTLGGGALTLTTSLT-LTGTLLTGGAGtLTLDSTSTWNITGTS------TLNVGNLTN-AGTIDLG 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 806 NG-VAGDTLTVNGDYTG-GGTLLLDSELNGDDSVSDQLVLNGNTAGNTTVVVNSITGIGEPTSTGIKVVDFAAdptqFQN 883
Cdd:cd01344 73 NGsPAGGTLTITGNYTGnGGTLRLNTVLGDDDSPTDRLVIDGDASGTTRVAVNNAGGSGATTGNGIEVVEVGG----TSS 148
|
170 180 190
....*....|....*....|....*....|....*...
gi 485781081 884 NAKFSLAgsGYVNMGAYDYTLV-----EDNNDWYLRSQ 916
Cdd:cd01344 149 NGAFSLA--GRVVAGAYEYRLYrggvsGNDGNWYLRSE 184
|
|
| Autotransporter |
pfam03797 |
Autotransporter beta-domain; Secretion of protein products occurs by a number of different ... |
983-1222 |
1.74e-23 |
|
Autotransporter beta-domain; Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type V pathway was first described for the IgA1 protease. The protein component that mediates secretion through the outer membrane is contained within the secreted protein itself, hence the proteins secreted in this way are called autotransporters. This family corresponds to the presumed integral membrane beta-barrel domain that transports the protein. This domain is found at the C terminus of the proteins it occurs in. The N terminus contains the variable passenger domain that is translocated across the membrane. Once the passenger domain is exported it is cleaved auto-catalytically in some proteins, in others a different protease is used and in some cases no cleavage occurs.
Pssm-ID: 461054 [Multi-domain] Cd Length: 255 Bit Score: 101.31 E-value: 1.74e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 983 LRVIGGRYHY-TAAGQLAQHEDTSTVQLSGDLFSGrwgddGEWMLGAVGGYSDnqgeSRSNMTGTRADNQNHGYAVGLTS 1061
Cdd:pfam03797 3 ARGFGGRGKQdGDGGAAGYDADTGGLQVGADYRLG-----DNLRLGVAFGYSR----SDADVDGRGGSGDSDSYSLGLYG 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 1062 SWYQHGnqkqGAWLDSWLQYAWFNNDVS-------EQDDGTDHYHSSGIIASLEAGYQWLPGRGVVIEPQAQVIYQGVQQ 1134
Cdd:pfam03797 74 TYYGDG----GWYLDGGLGYGWHDNDTRrsvdlggFSETAKGDYDGNGFGASLEAGYRFALGGGWTLEPFAGLAYVRLRL 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 1135 DDFTAANRA---RVSQSQGDDIQMRLGLHSEWR---TAVHVIPTLDLNYYHNPHSTEIEEDGS-----------TISDDA 1197
Cdd:pfam03797 150 DGFTESGGAaalSVDSQSYDSLTGRLGLRLSYTfdlGGGTLTPYARLGWRHEFGDDDPVTTAAfaglsgagsftVAGADL 229
|
250 260
....*....|....*....|....*
gi 485781081 1198 VKQRGEIKVGVTGNISQRVSLRGSV 1222
Cdd:pfam03797 230 ARDSLELGAGLSAQLSDNLSLYANY 254
|
|
| Autotransporter |
smart00869 |
Autotransporter beta-domain; Secretion of protein products occurs by a number of different ... |
983-1233 |
4.64e-23 |
|
Autotransporter beta-domain; Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type IV pathway was first described for the IgA1 protease. The protein component that mediates secretion through the outer membrane is contained within the secreted protein itself, hence the proteins secreted in this way are called autotransporters. This family corresponds to the presumed integral membrane beta-barrel domain that transports the protein. This domain is found at the C-terminus of the proteins it occurs in. The N-terminus contains the variable passenger domain that is translocated across the membrane. Once the passenger domain is exported it is cleaved auto-catalytically in some proteins, in others a different peptidase is used and in some cases no cleavage occurs.
Pssm-ID: 214872 [Multi-domain] Cd Length: 268 Bit Score: 100.34 E-value: 4.64e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 983 LRVIGGRYHYTAAGQLAQHE---DTSTVQLSGDLfsgRWGDDGEWMLGAVGGYSDNQGESRSNMTGTRADNqnHGYAVGL 1059
Cdd:smart00869 1 GRGLGGFLRQDSSGSGGSAGfdyDSYGLQLGADY---RLSDNGNLSLGFAAGYGNSKVDFSGNKGSGKGDV--DSYGLGL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 1060 TSSWYQHgnqkQGAWLDSWLQYAWFNNDVS------EQDDGTDHYHSSGIIASLEAGYQWLPGRGVVIEPQAQVIYQGVQ 1133
Cdd:smart00869 76 YAGYSLG----NGLYLDAQLGYGRSDNDTKrkvtlgGAGRAKGSYDGTGYGASLEAGYRFYLGGGLTLTPFAGLAYSRVR 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 1134 QDDFT----AANRARVSQSQGDDIQMRLGLHSEWRTAVH----VIPTLDLNYYH-----NPHST----EIEEDGSTISDD 1196
Cdd:smart00869 152 QDGFTesggGAFGLSVDSQSLDSLSLPLGLRLEYRLALGdgatLTPYLRLAYVHdfyddNPVVTasllGSGASFTTSGTD 231
|
250 260 270
....*....|....*....|....*....|....*..
gi 485781081 1197 AVKQRGEIKVGVTGNISQRVSLRGSVAWQKGSDDFAQ 1233
Cdd:smart00869 232 LDRNAAELGLGLSAKLSNGLSLSLNYDGEFGGSSRSH 268
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK09752 |
PRK09752 |
AIDA-I family autotransporter YfaL; |
1-1244 |
0e+00 |
|
AIDA-I family autotransporter YfaL;
Pssm-ID: 182059 [Multi-domain] Cd Length: 1250 Bit Score: 2196.77 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 1 MRIIFLRKEYLSLLPSMIASLFSANGFAAAIDLCQGYDIKASCHASRQSLSGITQDWSVADGQWLVFSDMTNNASGGAVF 80
Cdd:PRK09752 1 MRIIFLRKEYLSLLPSMIASLFSANGVAAVIDSCQGYDIKASCQASRQSLSGITQDWSIADGQWLVFSDMTNNASGGAVF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 81 LQQGAEFSLLPENETGMTLFANNTVTGEYNNGGAIFAKENSTLNLTDVIFSGNVAGGYGGAIYSSGTNDTGAVDLRVTNA 160
Cdd:PRK09752 81 LQQGAEFTLSPENETGMTLFANNTVSGEYNNGGAIFAKENSTLNLTDVIFSGNVAGGYGGAIYSSGTNDTGAVDLRVTNA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 161 MFRNNIANDGKGGAIYTINNDVYLSDVIFDNNQAYTSTSYSDGDGGAIDVTDNNSVSKHPSGYTIINNTAFTNNTAEGYG 240
Cdd:PRK09752 161 MFRNNIANDGKGGAIYTINNDVYLSDVIFDNNQAYTSTSYSDGDGGAIDVTDNNSDSKHPSGYTIINNTAFTNNTAEGYG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 241 GAIYTNSATAPYLIDISVDDSYSQNGGVLVDENNSAAGYGDGPSTAAGGFMYLGLSEVTFDIADGKTLVIGNTENDGAVD 320
Cdd:PRK09752 241 GAIYTNSATAPYLIDISVDDSYSQNGGVLVDENNSAAGYGDGPSSAAGGFMYLGLSEVTFDIADGKTLVIGNTENDGAVD 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 321 SIAGTGLITKTGSGDLVLNADNNDFTGEMQIENGEVTLGRSNSLMNVGDTHCQDDPQDCYGLTIGSIDKYQNQAELNVGS 400
Cdd:PRK09752 321 SIAGTGLITKTGSGDLVLNADNNDFTGEMQIENGEVTLGRSNSLMNVGDTHCQDDPQDCYGLTIGSIDKYQNQAELNVGS 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 401 TQQTFVHSLTGFQNGTLNIDAGGNVTVNQGSFAGTIEGAGQLTIAQNGSYVLSGAQSMALTGDIVVDDGAVLSLEGDAAD 480
Cdd:PRK09752 401 TQQTFVHSLTGFQNGTLNIDAGGNVTVNQGSFAGTIEGAGQLTIAQNGSYVLAGAQSMALTGDIVVDDGAVLSLEGDAAD 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 481 LAALQDDPQSIVLNGGVLDLSDFSTWQSGTSYNDGLEVSGSSGTVIGSQDVVDLAGGDNLHIGGDGKDGVYVVVDASDGQ 560
Cdd:PRK09752 481 LRALQDDPQSIVLNGGVLDLSDFSTWQSGTSYNDGLEVSGSSGTVIGSQDVVDLAGGDDLHIGGDGKDGVYVVIDAGDGQ 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 561 VSLANNNSYLGTTQIASGTLMVSDNSQLGDTHYNRQVIFTDKQQESVMEITANVDTRSTTTEHGRDIEMRADGEVAVDAG 640
Cdd:PRK09752 561 VSLANNNSYLGTTQIASGTLMVSDNSQLGDTHYNRQVIFTDKQQESVMEITADVDTRSTTTGHGRDIEMRADGEVAVDAG 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 641 VDTQWGALMADSSGQHQDEGSTLTKTGAGTLELTASGTTQSAVRVEEGTLKGDVADIFPYASSLWVGDGATFVTGADQDI 720
Cdd:PRK09752 641 VDTQWGALMADSSGQHQDEGSTLTKTGAGTLELTASGTTQSAVRVEEGTLKGDVADIIPYASSLWVGDGATFVTGADQDI 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 721 QSIDATSSGTIDISDGTVLRLTGQDTSVALNASLFNGDGTLVNATDGVTLTGELNTNLETDSLTYLSDVTVNGNLTNTSG 800
Cdd:PRK09752 721 QSIDATSSGTIDISDGTVLRLTGQDTSVALNASLFNGDGTLVNATDGVTLTGELNTNLETDSLTYLSDVTVNGNLTNTSG 800
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 801 AVSLQNGVAGDTLTVNGDYTGGGTLLLDSELNGDDSVSDQLVLNGNTAGNTTVVVNSITGIGEPTSTGIKVVDFAADPTQ 880
Cdd:PRK09752 801 AVSLQNGVAGDTLTVNGDYTGGGTLLLDSELNGDDSVSDQLVLNGNTAGNTTVVVNSITGIGEPTSTGIKVVDFAADPTQ 880
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 881 FQNNAKFSLAGSGYVNMGAYDYTLVEDNNDWYLRSQEVTPPLPPD----PDPDPTPDPDPTPD--PIPAYQPVLNAKVGG 954
Cdd:PRK09752 881 FQNNAQFSLAGSGYVNMGAYDYTLVEDNNDWYLRSQEVTPPSPPDpdptPDPDPTPDPDPTPDpePTPAYQPVLNAKVGG 960
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 955 YLNNLRAANQAFMMERRDHAGGNGQTLNLRVIGGRYHYTAAGQLAQHEDTSTVQLSGDLFSGRWGDDGEWMLGAVGGYSD 1034
Cdd:PRK09752 961 YLNNLRAANQAFMMERRDHAGGDGQTLNLRVIGGDYHYTAAGQLAQHEDTSTVQLSGDLFSGRWGDDGEWMLGIVGGYSD 1040
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 1035 NQGESRSNMTGTRADNQNHGYAVGLTSSWYQHGNQKQGAWLDSWLQYAWFNNDVSEQDDGTDHYHSSGIIASLEAGYQWL 1114
Cdd:PRK09752 1041 NQGDSRSNMTGTRADNQNHGYAVGLTSSWFQHGNQKQGAWLDSWLQYAWFNNDVSEQEDGTDHYHSSGIIASLEAGYQWL 1120
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 1115 PGRGVVIEPQAQVIYQGVQQDDFTAANRARVSQSQGDDIQMRLGLHSEWRTAVHVIPTLDLNYYHNPHSTEIEEDGSTIS 1194
Cdd:PRK09752 1121 PGRGVVIEPQAQVIYQGVQQDDFTAANHARVSQSQGDDIQTRLGLHSEWRTAVHVIPTLDLNYYHDPHSTEIEEDGSTIS 1200
|
1210 1220 1230 1240 1250
....*....|....*....|....*....|....*....|....*....|
gi 485781081 1195 DDAVKQRGEIKVGVTGNISQRVSLRGSVAWQKGSDDFAQMAGFLSMTVKW 1244
Cdd:PRK09752 1201 DDAVKQRGEIKVGVTGNISQRVSLRGSVAWQKGSDDFAQTAGFLSMTVKW 1250
|
|
| autotrans_barl |
TIGR01414 |
outer membrane autotransporter barrel domain; A number of Gram-negative bacterial proteins, ... |
806-1244 |
3.08e-89 |
|
outer membrane autotransporter barrel domain; A number of Gram-negative bacterial proteins, mostly found in pathogens and associated with virulence, contain a conserved C-terminal domain that integrates into the outer membrane and enables the N-terminal region to be delivered across the membrane. This C-terminal autotransporter domain is about 400 amino acids in length and includes the aromatic amino acid-rich OMP signal, typically ending with a Phe or Trp residue, at the extreme C-terminus. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]
Pssm-ID: 273608 [Multi-domain] Cd Length: 431 Bit Score: 295.45 E-value: 3.08e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 806 NGVAGDTLTVNGDYTGGGTLLLDSELNGDDSVSDQLVLNGNTAGNTTVVVNSITGIGEPTSTGIKVVDfaadpTQFQNNA 885
Cdd:TIGR01414 1 PGGAFNTLTVNGLYTGNGGFVMNTDLGGDNSQTDRLVVNGNASGTTGVVVNNIGGEGAQTGDGITLVT-----VNGGSDA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 886 KFSLAGsGYVNMGAYDYTLV----EDNNDWYLRSQEvtpplPPDPDPDPTPDPDPTPDPIPAYQPVLNAKVGGYLNNLRA 961
Cdd:TIGR01414 76 AFTLAN-GKVDAGAYTYTLYkngtEDNNNWYLTSSL-----PDLTPPGQQLSPTYRAEAGSYAANANAALFLAELDTLRQ 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 962 ANQAFMMERRDhaggNGQTLNLRVIGGRYHYTA-AGQLAQHEDTSTVQLSGDLFSGRWGdDGEWMLGAVGGYSDNQGESR 1040
Cdd:TIGR01414 150 RMGDLRSAARD----AGNGVWARIFGGDNHLDGdAGAAGYDQNTTGVQLGGDILLAGNA-DGDLHVGLMAGYAKADIKTR 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 1041 SNMTGtrADNQNHGYAVGLTSSWYQHGnqkqGAWLDSWLQYAWFNNDVSEQDDG---TDHYHSSGIIASLEAGYQWLPG- 1116
Cdd:TIGR01414 225 SYKYG--GKGKVDGYGLGLYGTWLQDS----GAYVDGVLQYSRFRNDVSSTGSNgkvSGKYNSNGFTASLEAGYRYNLGg 298
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 1117 RGVVIEPQAQVIYQGVQQDDFTAANRARVSQSQGDDIQMRLGLHSEWR----TAVHVIPTLDLNYYHNPH-STEIEEDGS 1191
Cdd:TIGR01414 299 NGWYVEPQAQLSYFGVSGDDYKESNGTRVLGGGGDSLQGRLGLRVGYQfdlgTGRAVKPYLKANVLHEFKgGTGVRVNGV 378
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 485781081 1192 TISDDAVKQRGEIKVGVTGNISQRVSLRGSVAWQKGSDDFAQMAGFLSMTVKW 1244
Cdd:TIGR01414 379 TIRNDFSGTRAEYGVGVNAKIKDNLSLYADVDYQKGGKKYTDNQGNLGVRYSF 431
|
|
| AidA |
COG3468 |
Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular ... |
410-1231 |
2.32e-80 |
|
Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442691 [Multi-domain] Cd Length: 846 Bit Score: 282.61 E-value: 2.32e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 410 TGFQNGTLNIDAGGNVTVNQGSFAGTIEGAGQLTIAQNGSYVLSGAQSMALTGDIVVDDGAVLSLEGDAADLAALQDDPQ 489
Cdd:COG3468 1 TASGGGGGATGLGGGGTGGGGGLGGTGGGNAGLGIGNGGGGGAASGSGAGGVAGNGGGGGGGAGGGGGGAGSGGGLAGAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 490 SIVLNGGVLDLSDFSTWQSGTSYNDGLEVSGSSGTVIGSQDVVDLAGGDNLHIGGDGKDGVYVVVDASDGQVSLANNNSY 569
Cdd:COG3468 81 SGGTGGNSTGGGGGNSGTGGTGGGGGGGGSGNGGGGGGGGGGGGTGGGGGGGTGSAGGGGGGGGGGTGVGGTGAAAAGGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 570 LGTTQIASGTLMVSDNSQLGDTHYNRQVIFTDKQQESVMEITANVDTRSTTTEHGRDIEMRADGEVAVDAGVDTQWGALM 649
Cdd:COG3468 161 TGSGGGGSGGGGGAGGGGGGGAGGSGGAGSTGSGAGGGGGGSGGGGGAAGTGGGGGGGGGAGGATGGAGSGGNTGGGVGG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 650 ADSSGQHQDEGSTLTKTGAGTLELTASGTTQSAVRVEEGTLKGDVADIFPYASSLWVGDGATFVTGADQDIQSIDATSSG 729
Cdd:COG3468 241 GGGSAGGTGGGGLTGGGAAGTGGGGGGTGTGSGGGGGGGANGGGSGGGGGASGTGGGGTASTGGGGGGGGGNGGGGGGGS 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 730 TIDISDGTVLRLTGQDTSVALNASLFNGDGTLVNATDGVTLTGELNTNLETDSLTYLSDVTVNGNLTNTSGAVSLQNGV- 808
Cdd:COG3468 321 NAGGGSGGGGGGGGGGGGGGTTLNGAGSAGGGTGAALAGTGGSGSGGGGGGGSGGGGGAGGGGANTGSDGVGTGLTTGGt 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 809 ------------------AGDTLTVNGDYTG-GGTLLLDSELNGDDSVSDQLVLNGNTAGNTTVVVNSITGIGEPTSTGI 869
Cdd:COG3468 401 gnnggggvgggggggltlTGGTLTVNGNYTGnNGTLVLNTVLGDDNSPTDRLVVNGNTSGTTGVRVNNAGGLGAQTVNGI 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 870 KVVDfaadpTQFQNNAKFSLagSGYVNMGAYDYTLV-----EDNNDWYLRSQEVTPPLPpdpdpdptpdpdptpdpipay 944
Cdd:COG3468 481 EVVE-----VNGASDGAFTL--GGRVVAGAYEYTLYqggsgGDDGNWYLRSTLTPPDPP--------------------- 532
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 945 QPVLNAKVGGYLNNLRAANQAFMMER----------RDHAGGNGQTLNLRVIGGRYHY-TAAGQLAQHEDTSTVQLSGDL 1013
Cdd:COG3468 533 TPVYRPEVPSYLANPAAANGLFELGTlhdrlgerryTDTGESDNSGAWLRVEGGHNRSrDSSGQLDYDSNRYGLQLGGDL 612
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 1014 FSGRwGDDGEWMLGAVGGYSDNQGESRSNMTGTrADNQNHGYAVGLTSSWYQHgnqkQGAWLDSWLQYAWFNNDVSEQDD 1093
Cdd:COG3468 613 LQWE-DGGGRLHVGVMAGYGNGDSDVRSRATGT-GKGDVDGYSLGLYGTWYGN----NGFYVDGVLQYSWFDNDVSSDDL 686
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 1094 G--TDHYHSSGIIASLEAGYQWLPGRGVVIEPQAQVIYQGVQQDDFTAANRARVSQSQGDDIQMRLGLH----SEWRTAV 1167
Cdd:COG3468 687 GgvTGSYDGNGYSASLEAGYPFKLGEGWSLEPQAQLIYQGVDFDDFTDSNGTRVSGDDGDSLQGRLGLRlgyeFHWDDGR 766
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 485781081 1168 HVIPTLDLNYYHNP-HSTEIEEDGSTISDDAVKQRGEIKVGVTGNISQRVSLRGSVAWQKGSDDF 1231
Cdd:COG3468 767 ALQPYLEANWLHEFlGDNSVTVNGVSFSQDGSGTWGELGLGVTGQLNKNLSLYGDVGYQTGLDGY 831
|
|
| PRK15313 |
PRK15313 |
intestinal colonization autotransporter adhesin MisL; |
709-1240 |
4.37e-52 |
|
intestinal colonization autotransporter adhesin MisL;
Pssm-ID: 237940 [Multi-domain] Cd Length: 955 Bit Score: 199.64 E-value: 4.37e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 709 GATFVTgaDQDIQSIDATS-SGTidisdgtvlrLTGQDTSVALNA---SLFNGDGTLVNATDGvtlTGELNTNLETDSLT 784
Cdd:PRK15313 365 GGRFVI--DGDIRAAGATAaSGT----------LPQQNSTIKLNMtdnSRWDGASYITSATAG---TGVISVQMSDATWN 429
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 785 YLSDVTVNgNLTNTSGAV---SLQNGVAGDTLTVNGDYTG-GGTLLLDSELNGDDSVSDQLVLNGNTAGNTTVVVNSITG 860
Cdd:PRK15313 430 MTSSSTLT-DLTLNSGATinfSHEDGEPWQTLTINEDYVGnGGKLVFNTVLNDDDSETDRLQVLGNTSGNTFVAVNNIGG 508
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 861 IGEPTSTGIKVVDFAADptqfqNNAKFSLAGSgyVNMGAYDYTLVEDNNDWYLRS------------------------- 915
Cdd:PRK15313 509 AGAQTIEGIEIVNVAGN-----SNGTFEKASR--IVAGAYDYNVVQKGKNWYLTSyiepdepiipdpvdpvipdpvipdp 581
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 916 ---------------------QEVTPPLPPDPDPDPTPDPDPTPDPIPAYQPVLNAKVGGYLNNLRAANQAFMMERRDHA 974
Cdd:PRK15313 582 vdpdpvdpvipdpvipdpvdpDPVDPEPVDPVIPDPTIPDIGQSDTPPITEHQFRPEVGSYLANNYAANTLFMTRLHDRL 661
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 975 GGNGQT-----------LNLRVIGGRYHYT-AAGQLAQHEDTSTVQLSGDLfsGRWGDDG--EWMLGAVGGYSDNQGESR 1040
Cdd:PRK15313 662 GETQYTdmltgekkvtsLWMRNVGAHTRFNdGSGQLKTRINSYVLQLGGDL--AQWSTDGldRWHIGAMAGYANSQNRTL 739
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 1041 SNMTGTRADNQNHGYAVGLTSSWYQHGNQKQGAWLDSWLQYAWFNNDVSEQDDGTDHYHSSGIIASLEAGYQWLPG---- 1116
Cdd:PRK15313 740 SSVSDYHSRGQVTGYSVGLYGTWYANNIDRSGAYVDTWMLYNWFDNKVMGQDQAAEKYKSKGITASVEAGYSFRLGesah 819
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 1117 RGVVIEPQAQVIYQGVQQDDFTAANRARVSQSQGDDIQMRLGLHS--------EWRTAVHVIPTLDLNYYHNPHSTEIEE 1188
Cdd:PRK15313 820 QSYWLQPKAQVVWMGVQADDNREANGTLVKDDTAGNLLTRMGVKAyinghnaiDDNKSREFQPFVEANWIHNTQPASVKM 899
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|..
gi 485781081 1189 DGSTISDDAVKQRGEIKVGVTGNISQRVSLRGSVAWQKGSDDFAQMAGFLSM 1240
Cdd:PRK15313 900 DDVSSDMRGTKNIGELKVGIEGQITPRLNVWGNVAQQVGDQGYSNTQGLLGV 951
|
|
| PRK14849 |
PRK14849 |
autotransporter barrel domain-containing lipoprotein; |
725-1244 |
2.45e-48 |
|
autotransporter barrel domain-containing lipoprotein;
Pssm-ID: 184851 [Multi-domain] Cd Length: 1806 Bit Score: 189.56 E-value: 2.45e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 725 ATSSGTIDISDGTVLrlTGQDTSVALNASLFNGDGTLVnATDGVTLTGELNtnLETDSLTYLSDVTVNGNLTNtSGAVSL 804
Cdd:PRK14849 1268 AAYQGTTDIVGGEIA--FGSDSAINMASQHINIHNSGV-MSGNVTTAGDVN--VMPGGTLRVAKTTIGGNLEN-GGTVQM 1341
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 805 --QNGVAGDTLTVNGDYTGG-GTLLLDSELNGDDSVSDQLVLNGNTAGNTTVVVNSITGIGEPTSTGIKVVDFAADPTqf 881
Cdd:PRK14849 1342 nsEGGKPGNVLTVNGNYTGNnGLMTFNATLGGDNSPTDKMNVKGDTQGNTRVRVDNIGGVGAQTVNGIELIEVGGNSA-- 1419
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 882 qnnAKFSLAgSGYVNMGAYDYTLVE----DNNDWYLRSQEvTPPLPPDPDPDPTPDPDPTPDPIPAYQPvlnaKVGGYLN 957
Cdd:PRK14849 1420 ---GNFALT-TGTVEAGAYVYTLAKgkgnDEKNWYLTSKW-DGVTPPDTPDPINNPPVVDPEGPSVYRP----EAGSYIS 1490
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 958 NLRAANQAFMMERRD-----------HAGGNGQTLNLRVIGGRYHYTAA-GQLAQHEDTSTVQLSGDLFSGRWGDDGEWM 1025
Cdd:PRK14849 1491 NIAAANSLFSHRLHDrlgepqyidslHSQGSASSMWMRHVGGHERSRAGdGQLNTQANRYVLQLGGDLAQWSSNAQDRWH 1570
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 1026 LGAVGGYSDNQGESRSNMTGTRADNQNHGYAVGLTSSWYQHGNQKQGAWLDSWLQYAWFNNDVSEQDDGTDHYHSSGIIA 1105
Cdd:PRK14849 1571 LGVMAGYANQHSNTQSNRVGYKSDGRISGYSAGLYATWYQNDANKTGAYVDSWALYNWFDNSVSSDNRSADDYDSRGVTA 1650
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 1106 SLEAGYQWLPG---------RGVVIEPQAQVIYQGVQQDDFTAANRARVSQSQGDDIQMRLGLHSEWRT--------AVH 1168
Cdd:PRK14849 1651 SVEGGYTFEAGtfsgsegtlNTWYVQPQAQITWMGVKDSDHTRKDGTRIETEGDGNVQTRLGVKTYLNShhqrddgkQRE 1730
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 485781081 1169 VIPTLDLNYYHNPHSTEIEEDGSTISDDAVKQRGEIKVGVTGNISQRVSLRGSVAWQKGSDDFAQMAGFLSMTVKW 1244
Cdd:PRK14849 1731 FQPYIEANWINNSKVYAVKMNGQTVGREGARNLGEVRTGVEAKVNNNLSLWGNVGVQLGDKGYSDTQGMLGVKYSW 1806
|
|
| PRK15319 |
PRK15319 |
fibronectin-binding autotransporter adhesin ShdA; |
631-1244 |
7.35e-40 |
|
fibronectin-binding autotransporter adhesin ShdA;
Pssm-ID: 185219 [Multi-domain] Cd Length: 2039 Bit Score: 162.17 E-value: 7.35e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 631 ADGEVAVDAGVDTQWGALMADSSGQHQDEGSTLTKTGAGTLELTASGTTQSAVRVEEGTLkgdvadifpyasslWV-GDG 709
Cdd:PRK15319 1428 AHGTFTLGAGDSFEVTSVLGDKTGNGDWDGKSLTKLGAGKLTLSGANTYTGDTNVQEGTL--------------WLsGDG 1493
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 710 ATFVTGADQdiqSIDATSSGTIDISDGTvlrltgqdtsvALNASLFNgDGTLVNAtdgvtltgelntnletDSLTYLSDV 789
Cdd:PRK15319 1494 SIGEMGSQQ---AVNVASGATFGGSNGT-----------TVNGKVTN-EGTLVFG----------------DSEETGAIF 1542
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 790 TVNGNLTN----TSGAVSlqnGVAGDTLTVNGDYTG-GGTLLLDSELNGDDSVSDQLVLNGNTAGNTTVVVNSItGIGEP 864
Cdd:PRK15319 1543 TLNGDLINmgtmTSGSSS---STPGNTLYVDGNYTGnGGSLYLNTVLGDDDSATDKLVITGDASGTTDLYINGI-GDGAQ 1618
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 865 TSTGIKVVDFAADPTqfqnNAKFSLAGSgyVNMGAYDYTLV--EDNNDWYLRSQEVT----------------------- 919
Cdd:PRK15319 1619 TTNGIEVVDVGGVST----SDAFELKNE--VNAGLYTYRLYwnESDNDWYLASKAQSddddsggddtpsdggddggnvtp 1692
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 920 ------PPLPPDPDPDPTPDPDPTPDPIPAYQPVLNAKVGGYLNNLRAANQAFMMERRDHAGGNGQTLN----LRVIGGR 989
Cdd:PRK15319 1693 pddggdGGNVTPPDDGGDGGDVTPPDHGGDVAPQYRADIGAYMGNQWMARNLQMQTLYDREGSQYRNADgsvwARFKAGK 1772
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 990 YHYTA-AGQLAQHEDTSTVQLSGDLFSgrWGDDGE-WMLGAVGGY----SDNQGESRSNMTGTRADNQNHGYAVGLTSSW 1063
Cdd:PRK15319 1773 AESEAvSGNIDMDSNYSQFQLGGDILA--WGNGQQsVTVGVMASYinadTDSTGNRGADGSQFTSSGNVDGYNLGVYATW 1850
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 1064 YQHGNQKQGAWLDSWLQYAWFNNDVSEQDDGTDHYHSSGIIASLEAGYQW----LPGRGVVIEPQAQVIYQGVQQDDFTA 1139
Cdd:PRK15319 1851 FADAQTHSGAYVDSWYQYGFYNNSVESGDAGSESYDSTANAVSLETGYRYdialSNGNTVSLTPQAQVVWQNYSADSVKD 1930
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 1140 ANRARVSQSQGDDIQMRLGLHSEWR----TAVHVIPTLDLNYYHNPHSTEIEEDGSTISDDAVKQRGEIKVGVTGNISQR 1215
Cdd:PRK15319 1931 NYGTRIDGQDGDSWTTRLGLRVDGKlykgSRTVIQPFAEANWLHTSDDVSVSFDDATVKQDLPANRAELKVGLQADIDKQ 2010
|
650 660
....*....|....*....|....*....
gi 485781081 1216 VSLRGSVAWQKGSDDFAQMAGFLSMTVKW 1244
Cdd:PRK15319 2011 WSVRAQVAGQTGSNDFGDLNGSLNLRYNW 2039
|
|
| auto_AIDA-I |
NF033176 |
autotransporter adhesin AIDA-I; |
747-1244 |
1.19e-35 |
|
autotransporter adhesin AIDA-I;
Pssm-ID: 380183 [Multi-domain] Cd Length: 1287 Bit Score: 147.88 E-value: 1.19e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 747 SVALNASLFNGDGTLVNATDGVTLTGELNT-------------NLETDS-LTY----LSDVTVNGNLTNTSGAV-SLQNG 807
Cdd:NF033176 767 SAVVNADMAVSQNAYINISDQATINGSVNNkgsvvinnsiingNITNDAdLSFgtakLLSATVNGSLVNNKNIIlNPTKE 846
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 808 VAGDTLTVNgDYTG--GGTLLLDSELNGDDSVSDQLVLNGNTAGNTTVVVNSITGIGEPTSTGIKVVDFAADptqfqNNA 885
Cdd:NF033176 847 SAGNTLTVS-NYTGtpGSVISLGGVLEGDNSLTDRLVVKGNTSGQSDIVYVNEGGSGGQTIEGINIISVEGN-----SDA 920
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 886 KFSLAGSgyVNMGAYDYTLVE------DNNDWYLRSQevtpplppdpdpdptpdpdPTPDPIPAYQPvlnaKVGGYLNNL 959
Cdd:NF033176 921 EFSLKNR--VVAGAYDYTLQKgnvsgtDKKGWYLTSH-------------------LPTSDTRQYRP----ENGSYATNM 975
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 960 RAANQAFMM---ERRDHAGGNGQT------LNLRVIGGRyhytAAGQLAQHEDTSTV-----QLSGDLFSGRWGDDGEWM 1025
Cdd:NF033176 976 ALANSLFLMdlnERKQFSAVNDNTqpesasVWMKITGGR----TSGKLSDGQNKTTTnqfinQLGGDIYKYHAEKLGDFT 1051
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 1026 LGAVGGYSDNQGESRSNMTGTRADNQNHGYAVGLTSSWYQHGNQKQGAWLDSWLQYAWFNNDVSEQDDGTDHYHSSGIIA 1105
Cdd:NF033176 1052 LGIMGGYANAKGKTINHTSKKGARNTLDGYSAGLYGTWYQNGANATGLFAETWMQYNWFNASVKGDGLEEEKYNLNGLTA 1131
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 1106 SLEAGYQ-----WLPGRGVV----IEPQAQVIYQGVQQDDFTAANRARVSQSQGDDIQMRLGLHSEWR--------TAVH 1168
Cdd:NF033176 1132 SVGGGYNlnvhtWTSPEGIKgefwLQPHLQAVWMGVTPDTHQEDNGTVVQGTGKNNLQTKAGIRASWKvkssldkdTGRE 1211
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 485781081 1169 VIPTLDLNYYHNPHSTEIEEDGSTISDDAVKQRGEIKVGVTGNISQRVSLRGSVAWQKGSDDFAQMAGFLSMTVKW 1244
Cdd:NF033176 1212 FRPYIEANWIHNTHEFGVKMSGDNQLLSGSRNQGEIKTGIEGVITQNLSVNGGVAYQAGGHGSNAISGALGIKYSF 1287
|
|
| PL2_Passenger_AT |
cd01344 |
Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of ... |
729-916 |
2.38e-33 |
|
Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43, AIDA-1 and IcsA, as well as, the less characterized ShdA, MisL, and BapA autotransporters.
Pssm-ID: 238654 [Multi-domain] Cd Length: 188 Bit Score: 127.42 E-value: 2.38e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 729 GTIDISDGTVL--RLTGQDTSVALNASLFnGDGTLVNATDG-VTLTGELNTNLETDSltylsdVTVNGNLTNtSGAVSLQ 805
Cdd:cd01344 1 GTITGNGGWKLggDLTLGGGALTLTTSLT-LTGTLLTGGAGtLTLDSTSTWNITGTS------TLNVGNLTN-AGTIDLG 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 806 NG-VAGDTLTVNGDYTG-GGTLLLDSELNGDDSVSDQLVLNGNTAGNTTVVVNSITGIGEPTSTGIKVVDFAAdptqFQN 883
Cdd:cd01344 73 NGsPAGGTLTITGNYTGnGGTLRLNTVLGDDDSPTDRLVIDGDASGTTRVAVNNAGGSGATTGNGIEVVEVGG----TSS 148
|
170 180 190
....*....|....*....|....*....|....*...
gi 485781081 884 NAKFSLAgsGYVNMGAYDYTLV-----EDNNDWYLRSQ 916
Cdd:cd01344 149 NGAFSLA--GRVVAGAYEYRLYrggvsGNDGNWYLRSE 184
|
|
| PL_Passenger_AT |
cd00253 |
Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V ... |
732-918 |
3.43e-29 |
|
Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain of autotransporters forms a pore in the outer membrane through which the N-terminal passenger domain is transported. Following transport, the passenger domain is generally cleaved by an outer membrane protease with the passenger domain either remaining in contact with the surface via a noncovalent interaction with the beta domain or cleaved to release a soluble protein. These proteins are highly diverse and perform a variety of functions that promote virulence, including catalyzing proteolysis, serving as an adhesin, mediating actin-promoted motility, or serving as a cytotoxin. Proteins in this family share similarity in the C-terminal region of the passenger domain as seen in the pertactin structure P.69, a Bordetella pertussis agglutinogen responsible for human pertussis. The P.69 protein consists of a 16-stranded parallel beta-helix with a V-shaped cross-section, and is one of the largest beta-helix known to date.
Pssm-ID: 238156 [Multi-domain] Cd Length: 186 Bit Score: 115.54 E-value: 3.43e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 732 DISDGTVLRLTGQDTSVALNASLFNGDGTLVNATDGVTLTGELNTNletDSLTYLSDVTVNGNLTNTSGAVSLQNG-VAG 810
Cdd:cd00253 2 TLSGNATINGGGDLTLGGGGALTLTGNSVWLGTLQAGGGTVSLNSN---SLWTLTGDSTVNGNLTNSGGTVDFGSAsGAF 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 811 DTLTVNGDYTGG-GTLLLDSELNGDDSVSDQLVLNGNTAGNTTVVVNSITGIGEPTSTGIKVVDfaadpTQFQNNAKFSL 889
Cdd:cd00253 79 NTLTVNGNYLGGnGTFVLNTDLGGDNSPTDKLVVTGNASGTTNVAVVNAGGEGASTGDGIELVE-----VNGGSDAAFSL 153
|
170 180 190
....*....|....*....|....*....|...
gi 485781081 890 AgsGYVNMGAYDYTL----VEDNNDWYLRSQEV 918
Cdd:cd00253 154 A--GRVDAGAYEYTLykggVGNNGNWYLRSTLA 184
|
|
| Autotransporter |
pfam03797 |
Autotransporter beta-domain; Secretion of protein products occurs by a number of different ... |
983-1222 |
1.74e-23 |
|
Autotransporter beta-domain; Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type V pathway was first described for the IgA1 protease. The protein component that mediates secretion through the outer membrane is contained within the secreted protein itself, hence the proteins secreted in this way are called autotransporters. This family corresponds to the presumed integral membrane beta-barrel domain that transports the protein. This domain is found at the C terminus of the proteins it occurs in. The N terminus contains the variable passenger domain that is translocated across the membrane. Once the passenger domain is exported it is cleaved auto-catalytically in some proteins, in others a different protease is used and in some cases no cleavage occurs.
Pssm-ID: 461054 [Multi-domain] Cd Length: 255 Bit Score: 101.31 E-value: 1.74e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 983 LRVIGGRYHY-TAAGQLAQHEDTSTVQLSGDLFSGrwgddGEWMLGAVGGYSDnqgeSRSNMTGTRADNQNHGYAVGLTS 1061
Cdd:pfam03797 3 ARGFGGRGKQdGDGGAAGYDADTGGLQVGADYRLG-----DNLRLGVAFGYSR----SDADVDGRGGSGDSDSYSLGLYG 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 1062 SWYQHGnqkqGAWLDSWLQYAWFNNDVS-------EQDDGTDHYHSSGIIASLEAGYQWLPGRGVVIEPQAQVIYQGVQQ 1134
Cdd:pfam03797 74 TYYGDG----GWYLDGGLGYGWHDNDTRrsvdlggFSETAKGDYDGNGFGASLEAGYRFALGGGWTLEPFAGLAYVRLRL 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 1135 DDFTAANRA---RVSQSQGDDIQMRLGLHSEWR---TAVHVIPTLDLNYYHNPHSTEIEEDGS-----------TISDDA 1197
Cdd:pfam03797 150 DGFTESGGAaalSVDSQSYDSLTGRLGLRLSYTfdlGGGTLTPYARLGWRHEFGDDDPVTTAAfaglsgagsftVAGADL 229
|
250 260
....*....|....*....|....*
gi 485781081 1198 VKQRGEIKVGVTGNISQRVSLRGSV 1222
Cdd:pfam03797 230 ARDSLELGAGLSAQLSDNLSLYANY 254
|
|
| Autotransporter |
smart00869 |
Autotransporter beta-domain; Secretion of protein products occurs by a number of different ... |
983-1233 |
4.64e-23 |
|
Autotransporter beta-domain; Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type IV pathway was first described for the IgA1 protease. The protein component that mediates secretion through the outer membrane is contained within the secreted protein itself, hence the proteins secreted in this way are called autotransporters. This family corresponds to the presumed integral membrane beta-barrel domain that transports the protein. This domain is found at the C-terminus of the proteins it occurs in. The N-terminus contains the variable passenger domain that is translocated across the membrane. Once the passenger domain is exported it is cleaved auto-catalytically in some proteins, in others a different peptidase is used and in some cases no cleavage occurs.
Pssm-ID: 214872 [Multi-domain] Cd Length: 268 Bit Score: 100.34 E-value: 4.64e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 983 LRVIGGRYHYTAAGQLAQHE---DTSTVQLSGDLfsgRWGDDGEWMLGAVGGYSDNQGESRSNMTGTRADNqnHGYAVGL 1059
Cdd:smart00869 1 GRGLGGFLRQDSSGSGGSAGfdyDSYGLQLGADY---RLSDNGNLSLGFAAGYGNSKVDFSGNKGSGKGDV--DSYGLGL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 1060 TSSWYQHgnqkQGAWLDSWLQYAWFNNDVS------EQDDGTDHYHSSGIIASLEAGYQWLPGRGVVIEPQAQVIYQGVQ 1133
Cdd:smart00869 76 YAGYSLG----NGLYLDAQLGYGRSDNDTKrkvtlgGAGRAKGSYDGTGYGASLEAGYRFYLGGGLTLTPFAGLAYSRVR 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 1134 QDDFT----AANRARVSQSQGDDIQMRLGLHSEWRTAVH----VIPTLDLNYYH-----NPHST----EIEEDGSTISDD 1196
Cdd:smart00869 152 QDGFTesggGAFGLSVDSQSLDSLSLPLGLRLEYRLALGdgatLTPYLRLAYVHdfyddNPVVTasllGSGASFTTSGTD 231
|
250 260 270
....*....|....*....|....*....|....*..
gi 485781081 1197 AVKQRGEIKVGVTGNISQRVSLRGSVAWQKGSDDFAQ 1233
Cdd:smart00869 232 LDRNAAELGLGLSAKLSNGLSLSLNYDGEFGGSSRSH 268
|
|
| AC_1 |
pfam18883 |
Autochaperone Domain Type 1; This entry represents the autochaperone domain of type 1 (AC-1) ... |
793-904 |
2.97e-15 |
|
Autochaperone Domain Type 1; This entry represents the autochaperone domain of type 1 (AC-1) in the Type Va Secretion System (T5aSS). Autotransporters (ATs) belong to a family of modular proteins secreted by the Type V, subtype a, secretion system (T5aSS) and considered as an important source of virulence factors in lipopolysaccharidic diderm bacteria (archetypical Gram-negative bacteria). The AC of type 1 with beta-fold appears as a prevalent and conserved structural element exclusively associated to beta-helical AT passenger.
Pssm-ID: 465898 [Multi-domain] Cd Length: 114 Bit Score: 73.03 E-value: 2.97e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 793 GNLTNTSGAVSLQ--NGVAGDTLTVNGDYTG-GGTLLLDSELNGDDSVSDQLVLNGNTA-GNTTVVVNSITGIGEPTST- 867
Cdd:pfam18883 4 TNLTNDNSTINFTapSGASYKTLTVDGDYTGnDGTLALNTYLGGDGSPSDKLVIDGGTAsGTTNLRINNTGGPGALTTNd 83
|
90 100 110
....*....|....*....|....*....|....*..
gi 485781081 868 GIKVVDfAADPTQFQnnaKFSLagSGYVNMGAYDYTL 904
Cdd:pfam18883 84 GILVVD-VGGTTSDG---AFRL--AGRAVAGPYEYLL 114
|
|
| PL1_Passenger_AT |
cd01343 |
Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of ... |
700-913 |
1.52e-12 |
|
Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of Neisseria and Haemophilus IgA1 proteases, SPATEs (serine protease autotransporters secreted by Enterobacteriaceae), Bordetella pertacins, and nonprotease autotransporters, TibA and similar AIDA-like proteins.
Pssm-ID: 238653 [Multi-domain] Cd Length: 233 Bit Score: 68.54 E-value: 1.52e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 700 YASSLWVGDGATFVTGadqDIQSIDATSSGTIDISD--GTVLrLTGQDTSVALNASLFNGDGTLVNATDGVTLTGELNTN 777
Cdd:cd01343 26 YGSSVTLTNGAVLDAG---NANLSAAASYATLSGSNirGTVV-LGAGQPLQALAELLLGGNAAWTGAIQGLNATVSLNLN 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 778 letdSLTYLSDVTVNGNLTNTSGAVSLQNGVAGD--TLTVNgDYTGGGTLLLDSELNGDDSvsDQLVLNGNTAGNTTVVV 855
Cdd:cd01343 102 ----SVWTLTGDSNVNNLTLNGGTVDFNGPSAGKfnTLTVN-TLSGNGTFVMRTDLAGGQG--DKLVVTGSATGDFNLLV 174
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 856 NSITGigEPTS-TGIKVVDfaadpTQFQNNAKFSLAGsGYVNMGAYDYTLVED-NNDWYL 913
Cdd:cd01343 175 VNTGK--EPTSgLNLTLVS-----TPKGGDAEFTLAN-GTVDLGAYRYTLVKDgNGNWTL 226
|
|
| FhaB |
COG3210 |
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ... |
48-1141 |
6.84e-11 |
|
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442443 [Multi-domain] Cd Length: 1698 Bit Score: 67.10 E-value: 6.84e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 48 QSLSGITQDWSVADGQWLVFSDMTNNASGGAVFLQQGAEFSLLPENETGMTLFANNTVTGEYNNGGAIFAKENSTLNLTD 127
Cdd:COG3210 434 GITGNGTVTGGTIGGLTGSGTTNGAGLSGNTDVSGTGTVTNSAGNTTSATTLAGGGIGTVTTNATISNNAGGDANGIATG 513
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 128 VIFSGNVAGGYGGAIYSSGTNDTGAVDLRVTNAMFRNNIANDGKGGAIYTINNDVYLSDVIFDNNQAYTSTSYSDGDGGA 207
Cdd:COG3210 514 LTGITAGGGGGGNATSGGTGGDGTTLSGSGLTTTVSGGASGTTAASGSNTANTLGVLAATGGTSNATTAGNSTSATGGTG 593
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 208 IDVTDNNSVSKHPSGYTIINNTAFTNNTAEGYGGAIYTNSATAPYLIDISVDDSYSQNGGVLVDENNSAAGYGDGPSTAA 287
Cdd:COG3210 594 TNSGGTVLSIGTGSAGATGTITLGAGTSGAGANATGGGAGLTGSAVGAALSGTGSGTTGTASANGSNTTGVNTAGGTGGG 673
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 288 GGFMYLGLSEVTFDIADGKTLVIGNTENDGAVDSIAGTGlITKTGSGDLVLNADNNDFTGEMQIENGEVTLGRSNSLMNV 367
Cdd:COG3210 674 TTGTVTSGATGGTTGTTLNAATGGTLNNAGNTLTISTGS-ITVTGQIGALANANGDTVTFGNLGTGATLTLNAGVTITSG 752
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 368 GDTHCQDDPQDCYGLTIGSIDKYQNQAELNVGSTQQTFVHSLTGFQNGTLNIDAGGNVTVNQGSFAGTI---EGAGQLTI 444
Cdd:COG3210 753 NAGTLSIGLTANTTASGTTLTLANANGNTSAGATLDNAGAEISIDITADGTITAAGTTAINVTGSGGTItinTATTGLTG 832
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 445 AQNGSYVLSGAQSMALTGDIVVDDGAVLSLEGDAADLAALQDDPQSIVLNGGVLDLSDFSTWQSGTSYNDGLEVSGSSGT 524
Cdd:COG3210 833 TGDTTSGAGGSNTTDTTTGTTSDGASGGGTAGANSGSLAATAASITVGSGGVATSTGTANAGTLTNLGTTTNAASGNGAV 912
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 525 VIGSQDVVDLAGGDNLHIGGDGKDGVYVVVDASDGQVSLANNNSYLGTTQIASGTLMVSDNSQLGDTHYNRQVIFTDKQQ 604
Cdd:COG3210 913 LATVTATGTGGGGLTGGNAAAGGTGAGNGTTALSGTQGNAGLSAASASDGAGDTGASSAAGSSAVGTSANSAGSTGGVIA 992
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 605 ESVMEITANVDTRSTTTEHGRDIEMRADGEVAVDAGVDTQWGALMADSSGQHQDEGSTLTKTGAGTLELTASGTTQSAVR 684
Cdd:COG3210 993 ATGILVAGNSGTTASTTGGSGAIVAGGNGVTGTTGTASATGTGTAATAGGQNGVGVNASGISGGNAAALTASGTAGTTGG 1072
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 685 VEEGTLKGDVADIFPYASSLWVGDGATFVTGADqDIQSIDATSSGTIDISDGTVLRLTGQDTSVALNASLFNGDGTLVNA 764
Cdd:COG3210 1073 TAASNGGGGTAQASGAGTTHTLGGITNGGATGT-SGGTTTSTGGVTASKVGGTTTVGATGTSTASTEAAGAGTLTGLVAV 1151
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 765 TDGVTLTGELNTNLETDSLTYLSDVTVNGNLTNTSGAVSLQNGVAGDTLTVNGDYTGGGTLLLDSELNGDDSVSDQLVLN 844
Cdd:COG3210 1152 SAVAGGASSASAGDTTAVAAATTTTTGSAINGGADSAATEGTAGTDLKGGDSTGGSTTTIGTTNVTTTTTLTASDTGNTT 1231
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 845 GNTAGNTTVVVNSITGIGEPTSTGIKVVDFAADPTQFQNNAKFSLAGSGYVNMGAYDYTLVEDNNDWYLRSQEVTPPLPP 924
Cdd:COG3210 1232 ATGGSSAGQTGSFVAAGSASGTGDATTGATAGAVSNGATSTVAGNAGATATGSTVDIGSTSATSAGGSLDTTGNTAGANG 1311
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 925 DPDPDPTPDPDPTPDPIPAYQPVLNAKVGGYLNNLRAANQAFMMERRDHAGGNGQTLNLRVIGGRYHYTAAGQLAQHEDT 1004
Cdd:COG3210 1312 ATVGTGIGGTTATGTAVAAVNSGGVNAGGGTINTTAANTGLNGGNGATDSAAGAGSGGAAGSLAATAGAGTVLTGAGNNT 1391
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 1005 STVQLSGDLFSGRWGDDGEWMLGAVGGYSDNQGESRSNMTGTRADNQNHGYAVGLTSSWYQHGNQKQGAWLDSWLQYAWF 1084
Cdd:COG3210 1392 GAEGTNAGRDGGVTTSGTGVGNNGGVSGTTVAGTTGSSATTGTGGTGNTTGTSVAGAGGGNADASAINTGNASSLGAGGS 1471
|
1050 1060 1070 1080 1090
....*....|....*....|....*....|....*....|....*....|....*..
gi 485781081 1085 NNDVSEQDDGTDHYHSSGIIASLEAGYQWLPGRGVVIEPQAQVIYQGVQQDDFTAAN 1141
Cdd:COG3210 1472 TAGNAVGGAVIGGTTTGGNGAGVAGATASNGGTSTGAGGTAGGTTAEVAKASLEGGE 1528
|
|
| AidA |
COG3468 |
Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular ... |
120-545 |
2.90e-06 |
|
Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442691 [Multi-domain] Cd Length: 846 Bit Score: 51.87 E-value: 2.90e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 120 NSTLNLTDVIFSGNVAGGYGGAIYSSGTNDTGAVDLRVTNAMFRNNIANDGKGGAIYTINNDVYLSDVIFDNNQAYTSTS 199
Cdd:COG3468 2 ASGGGGGATGLGGGGTGGGGGLGGTGGGNAGLGIGNGGGGGAASGSGAGGVAGNGGGGGGGAGGGGGGAGSGGGLAGAGS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 200 YSDGDGGAIDVTDNNSVSKHPSGYTIINNTAFTNNTAEGYGGAIYTNSATAPYLIDISVDDSYSQNGGVLVDENNSAAGY 279
Cdd:COG3468 82 GGTGGNSTGGGGGNSGTGGTGGGGGGGGSGNGGGGGGGGGGGGTGGGGGGGTGSAGGGGGGGGGGTGVGGTGAAAAGGGT 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 280 GDGPSTAAGGFMYLGLSEVTFDIADGKTLVIGNTENDGAVDSIAGTGLITKTGSGDLVLNADNNDFTGEMQIENGEVTLG 359
Cdd:COG3468 162 GSGGGGSGGGGGAGGGGGGGAGGSGGAGSTGSGAGGGGGGSGGGGGAAGTGGGGGGGGGAGGATGGAGSGGNTGGGVGGG 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 360 RSNSLMNVGDTHCQDDPQDCYGLTIGSIDKYQNQAELNVGSTQQTFVHSLTGFQNGTLNIDAGGNVTVNQGSFAGTIEGA 439
Cdd:COG3468 242 GGSAGGTGGGGLTGGGAAGTGGGGGGTGTGSGGGGGGGANGGGSGGGGGASGTGGGGTASTGGGGGGGGGNGGGGGGGSN 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 440 GQLTIAQNGSYVLSGAQSMALTGDIVVDDGAVLSLEGDAADLAALQDDP-QSIVLNGGVLDLSDFSTWQSGTSYNDGLEV 518
Cdd:COG3468 322 AGGGSGGGGGGGGGGGGGGTTLNGAGSAGGGTGAALAGTGGSGSGGGGGgGSGGGGGAGGGGANTGSDGVGTGLTTGGTG 401
|
410 420
....*....|....*....|....*..
gi 485781081 519 SGSSGTVIGSQDVVDLAGGDNLHIGGD 545
Cdd:COG3468 402 NNGGGGVGGGGGGGLTLTGGTLTVNGN 428
|
|
| Pertactin |
pfam03212 |
Pertactin; |
812-913 |
8.18e-04 |
|
Pertactin;
Pssm-ID: 460848 [Multi-domain] Cd Length: 121 Bit Score: 40.45 E-value: 8.18e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 812 TLTVNGdYTGGGTLLLDSELngDDSVSDQLVLNGNTAGNTTVVVNSiTGiGEPTSTGiKVVDFAADPtqfQNNAKFSLAG 891
Cdd:pfam03212 25 TLTTQT-LSGSGTFVMNADV--ASGTGDQLVVSGNASGQHVLLVRN-TG-SEPASGN-TKLTLVETG---GGDAAFTLGN 95
|
90 100
....*....|....*....|....
gi 485781081 892 SG-YVNMGAYDYTLVEDNN-DWYL 913
Cdd:pfam03212 96 KGgKVDAGTYRYRLTADGNgNWSL 119
|
|
| RhsA |
COG3209 |
Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction ... |
230-1007 |
1.45e-03 |
|
Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only];
Pssm-ID: 442442 [Multi-domain] Cd Length: 1103 Bit Score: 43.21 E-value: 1.45e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 230 AFTNNTAEGYGGAIYTNSATAPYLIDISVDDSYSQNGGVLVDENNSAAGYGDGPSTAAGGFMYLGLSEVTFDIADGKTLV 309
Cdd:COG3209 1 ETSLGLVGGTTGASSTLLAATNAGGGTAVTNAGSTVLLAKGGLSTAAAAGGAATLTARSASTTDVVGTLTGAGGTSAGGV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 310 IGNTENDGAVDSIAGTGLITKTGSGDLVLNADNNDFTGEMQIENGEVTLGRSNSLMNVGDTHCQDDPQDCYGLTIGSIDK 389
Cdd:COG3209 81 TALGDASAAGGGYVGGAAAGGGATLTGLAAATASAGRLVSTGAGAGGTVTAATGGTLGATAGSATTGSTDGGRGGVAVTG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 390 YQNQAE-LNVGSTQQTFVHSLTGFQNGTLNIDAGGNVTVNQGSFAGTIEGAGQLTIAQNGSYVLSGAQSMALTGDIVVDD 468
Cdd:COG3209 161 LAGGGAsAYGLTLGGAAAGPATGVGTGAVTLATGLAGSALLALGSGAILGGLAGAYSGSATTATGTALGTPASVAATVTG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 469 GAVLSLEGDAADLAALQDDPQSIVLNGGVLDLSDFSTWQSGTSYNDGLEVSGSSGTVIGSQDVVDLAGGDNLHIGGDGKD 548
Cdd:COG3209 241 SATGAAGAGAAVATAATTLGGTTGAGTGASGAGLDASTGTGGAGGSNAAATAGGLGGAGLGSGGAGGGGTAGGTTTAAGT 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 549 GVYVVVDASDGQVSLANNNSYLGTTQIASGTLMVSDNSQLGDTHYNRQVIFTDKQQESVMEITANVDTRSTTTEHGRDIE 628
Cdd:COG3209 321 TGTAAVSGAADAGTTTTTGTGTGGTTTTVGGGGSLTLGGYGAAGGLTTSVGAGGGGSTSGSTTTVGGGGTATGSGGGSST 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 629 MRADGEVAVDAGVDTQWGALMADSSGQHQDEGSTLTKTGAGTLELTASGTTQSAVRVEEGTLKGDVADIFPYASSLWVGD 708
Cdd:COG3209 401 TGVGAGTTTTSTTGGDGGPATAAGALTAGGTATGTGTGGGGTTAGTDATTTTGGAGASGTLTTTGGAATGATTGGGTEAG 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 709 GATFVTGADQDIQSIDATSSGTIDISDGTVLRLTGQDTSVALNASLFNGDGTLVNATDGVTLTGELNTNLETDSLTYLSD 788
Cdd:COG3209 481 TGGGTLTSGSAGATTLGTDTTLDDTLGGTTTTTAGARGLVVTTGTTLTLGTTTTATLSATDATGTGDTTTTGTVGTGTST 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 789 VTVNGNLTNTSGAVSLQNGVAGDTLTVNGDYTGGGTLLLDSELNGDDSVSDQLVLNGNTAGNTTVVVNSITGIGEPTSTG 868
Cdd:COG3209 561 GTGGTGTVTTTGDGTGGASTTTGTTGGTATTTTVTTTTTTSTAGTTTTTTSGYTRAGLTLTLGTGTASGLERATASTGST 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485781081 869 IKVVDFAADPTQFQNNAKFSLAGSGYVNMGAYDYTLVEDNNDWYLRSQEVTPPLPPDPDPDPTPDPDPTPDPIPAYQPVL 948
Cdd:COG3209 641 TGGTTGTGVTTTGTTTTRATGTTGTGTGVTAGLTTLATGGTTVGGGTGTTSTATTGATTGGTETGTTVTTLAGGTTTRLG 720
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....*....
gi 485781081 949 NAKVGGYLNNLRAANQAFmmERRDHAGGNGQTLNLRVIGGRYHYTAAGQLAQHEDTSTV 1007
Cdd:COG3209 721 TTTTGGGGGTTTDGTGTG--GTTGTLTTTSTTTTTTAGALTYTYDALGRLTSETTPGGV 777
|
|
| PATR |
pfam12951 |
Passenger-associated-transport-repeat; This Autotransporter-associated beta strand repeat ... |
663-690 |
7.36e-03 |
|
Passenger-associated-transport-repeat; This Autotransporter-associated beta strand repeat model represents a core 32-residue region of a class of bacterial protein repeat found in one to 30 copies per protein. Most proteins with a copy of this repeat have domains associated with membrane autotransporters (pfam03797). The repeats occur with a periodicity of 60 to 100 residues. A pattern of sequence conservation is that every second residue is well-conserved across most of the domain. These repeats as likely to have a beta-helical structure. This repeat plays a role in the efficient transport of autotransporter virulence factors to the bacterial surface during growth and infection. The repeat is always associated with the passenger domain of the autotransporter. For these reasons it has been coined the Passenger-associated Transport Repeat (PATR). The mechanism by which the PATR motif promotes transport is uncertain but it is likely that the conserved glycines (see HMM Logo) are required for flexibility of folding and that this folding drives secretion. Autotransporters that contain PATR(s) associate with distinct virulence traits such as subtilisin (S8) type protease domains and polymorphic outer-membrane protein repeats, whilst SPATE (S6) type protease and lipase-like autotransporters do not tend to contain PATR motifs.
Pssm-ID: 463760 [Multi-domain] Cd Length: 28 Bit Score: 35.01 E-value: 7.36e-03
10 20
....*....|....*....|....*...
gi 485781081 663 LTKTGAGTLELTASGTTQSAVRVEEGTL 690
Cdd:pfam12951 1 LTKTGAGTLTLTGANTYTGGTTVNAGTL 28
|
|
| |
