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Conserved domains on  [gi|485718361|ref|WP_001349997|]
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MULTISPECIES: DUF3748 domain-containing protein [Enterobacteriaceae]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF3748 pfam12566
Protein of unknown function (DUF3748); This domain family is found in bacteria and eukaryotes, ...
 63-178 5.99e-73

Protein of unknown function (DUF3748); This domain family is found in bacteria and eukaryotes, and is approximately 120 amino acids in length. It is likely to contain 2 to 3 copies of a PD40-like repeat.


:

Pssm-ID: 432640  Cd Length: 119  Bit Score: 223.42  E-value: 5.99e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485718361   63 HVGVVTVHPKSEKYVFIHGPENPDETWHYDFHHRRGVIAEG---GKVSNLDAMDITAPYTPGALRGGSHVHVFSPNGERV 139
Cdd:pfam12566   1 HVGVVTVSPQENRYVFIHGPENPDPQWQYDFHHRRGVIVEDdepGQAITLDAMDITPPYTPGALRGGSHVHVFSPDGQWV 80

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 485718361  140 SFTYNDHVMHELDPALDLRNVGVAAPFGPFNVQKQHPRE 178
Cdd:pfam12566  81 SFTYNDHVLHELDPALDLRNVGVAVPLGPVVVNKHHPRE 119
TolB COG0823
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ...
 270-403 2.05e-15

Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];


:

Pssm-ID: 440585 [Multi-domain]  Cd Length: 158  Bit Score: 73.17  E-value: 2.05e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485718361 270 RRLTFThhrayPGLVNVPRhWvrcNPQGTQIAFlMRDDNGIVQLWLISPQGGEPRQLTHNKTDIQSAFnWHPSGEWLGFV 349
Cdd:COG0823   24 RRLTNS-----PGIDTSPA-W---SPDGRRIAF-TSDRGGGPQIYVVDADGGEPRRLTFGGGYNASPS-WSPDGKRLAFV 92

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 485718361 350 LDN----RIACAHAQSGEVEYLTENHANPpsadavVFSPDGQWLAWM--EGG--QLWITETD 403
Cdd:COG0823   93 SRSdgrfDIYVLDLDGGAPRRLTDGPGSP------SWSPDGRRIVFSsdRGGrpDLYVVDLD 148
 
Name Accession Description Interval E-value
DUF3748 pfam12566
Protein of unknown function (DUF3748); This domain family is found in bacteria and eukaryotes, ...
 63-178 5.99e-73

Protein of unknown function (DUF3748); This domain family is found in bacteria and eukaryotes, and is approximately 120 amino acids in length. It is likely to contain 2 to 3 copies of a PD40-like repeat.


Pssm-ID: 432640  Cd Length: 119  Bit Score: 223.42  E-value: 5.99e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485718361   63 HVGVVTVHPKSEKYVFIHGPENPDETWHYDFHHRRGVIAEG---GKVSNLDAMDITAPYTPGALRGGSHVHVFSPNGERV 139
Cdd:pfam12566   1 HVGVVTVSPQENRYVFIHGPENPDPQWQYDFHHRRGVIVEDdepGQAITLDAMDITPPYTPGALRGGSHVHVFSPDGQWV 80

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 485718361  140 SFTYNDHVMHELDPALDLRNVGVAAPFGPFNVQKQHPRE 178
Cdd:pfam12566  81 SFTYNDHVLHELDPALDLRNVGVAVPLGPVVVNKHHPRE 119
TolB COG0823
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ...
 270-403 2.05e-15

Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440585 [Multi-domain]  Cd Length: 158  Bit Score: 73.17  E-value: 2.05e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485718361 270 RRLTFThhrayPGLVNVPRhWvrcNPQGTQIAFlMRDDNGIVQLWLISPQGGEPRQLTHNKTDIQSAFnWHPSGEWLGFV 349
Cdd:COG0823   24 RRLTNS-----PGIDTSPA-W---SPDGRRIAF-TSDRGGGPQIYVVDADGGEPRRLTFGGGYNASPS-WSPDGKRLAFV 92

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 485718361 350 LDN----RIACAHAQSGEVEYLTENHANPpsadavVFSPDGQWLAWM--EGG--QLWITETD 403
Cdd:COG0823   93 SRSdgrfDIYVLDLDGGAPRRLTDGPGSP------SWSPDGRRIVFSsdRGGrpDLYVVDLD 148
TolB COG0823
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ...
 13-142 8.11e-03

Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440585 [Multi-domain]  Cd Length: 158  Bit Score: 36.96  E-value: 8.11e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485718361  13 LTNTN------TWTPDSQWLVFDVRPSGasftGETIERVNIHTGEVEVIyrASQGAHVGVVTVHPKSEKYVFIHGPENPD 86
Cdd:COG0823   26 LTNSPgidtspAWSPDGRRIAFTSDRGG----GPQIYVVDADGGEPRRL--TFGGGYNASPSWSPDGKRLAFVSRSDGRF 99

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 485718361  87 ETWHYDfhhrrgviAEGGKVSNLdamdITAPYTPgalrggshvhVFSPNGERVSFT 142
Cdd:COG0823  100 DIYVLD--------LDGGAPRRL----TDGPGSP----------SWSPDGRRIVFS 133
 
Name Accession Description Interval E-value
DUF3748 pfam12566
Protein of unknown function (DUF3748); This domain family is found in bacteria and eukaryotes, ...
 63-178 5.99e-73

Protein of unknown function (DUF3748); This domain family is found in bacteria and eukaryotes, and is approximately 120 amino acids in length. It is likely to contain 2 to 3 copies of a PD40-like repeat.


Pssm-ID: 432640  Cd Length: 119  Bit Score: 223.42  E-value: 5.99e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485718361   63 HVGVVTVHPKSEKYVFIHGPENPDETWHYDFHHRRGVIAEG---GKVSNLDAMDITAPYTPGALRGGSHVHVFSPNGERV 139
Cdd:pfam12566   1 HVGVVTVSPQENRYVFIHGPENPDPQWQYDFHHRRGVIVEDdepGQAITLDAMDITPPYTPGALRGGSHVHVFSPDGQWV 80

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 485718361  140 SFTYNDHVMHELDPALDLRNVGVAAPFGPFNVQKQHPRE 178
Cdd:pfam12566  81 SFTYNDHVLHELDPALDLRNVGVAVPLGPVVVNKHHPRE 119
TolB COG0823
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ...
 270-403 2.05e-15

Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440585 [Multi-domain]  Cd Length: 158  Bit Score: 73.17  E-value: 2.05e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485718361 270 RRLTFThhrayPGLVNVPRhWvrcNPQGTQIAFlMRDDNGIVQLWLISPQGGEPRQLTHNKTDIQSAFnWHPSGEWLGFV 349
Cdd:COG0823   24 RRLTNS-----PGIDTSPA-W---SPDGRRIAF-TSDRGGGPQIYVVDADGGEPRRLTFGGGYNASPS-WSPDGKRLAFV 92

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 485718361 350 LDN----RIACAHAQSGEVEYLTENHANPpsadavVFSPDGQWLAWM--EGG--QLWITETD 403
Cdd:COG0823   93 SRSdgrfDIYVLDLDGGAPRRLTDGPGSP------SWSPDGRRIVFSsdRGGrpDLYVVDLD 148
TolB COG0823
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ...
 300-403 1.52e-10

Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440585 [Multi-domain]  Cd Length: 158  Bit Score: 59.30  E-value: 1.52e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485718361 300 IAFlMRDDNGIVQLWLISPQGGEPRQLTHNKTDIQSAFnWHPSGEWLGFVLD----NRIACAHAQSGEVEYLTenhANPP 375
Cdd:COG0823    1 LAF-TLSRDGNSDIYVVDLDGGEPRRLTNSPGIDTSPA-WSPDGRRIAFTSDrgggPQIYVVDADGGEPRRLT---FGGG 75

                         90       100       110
                 ....*....|....*....|....*....|..
gi 485718361 376 SADAVVFSPDGQWLAW--MEGG--QLWITETD 403
Cdd:COG0823   76 YNASPSWSPDGKRLAFvsRSDGrfDIYVLDLD 107
COG4946 COG4946
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown] ...
 295-391 4.53e-07

Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown];


Pssm-ID: 443973 [Multi-domain]  Cd Length: 1072  Bit Score: 51.96  E-value: 4.53e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485718361  295 PQGTQIAFLmRDDNGIVQLWLISPQG-GEPRQLTHNKtdiqSAFNWHPS----GEWLGFVlDNR-------IAcahaqSG 362
Cdd:COG4946   352 PDGKSIAYF-SDASGEYELYIAPADGsGEPKQLTLGD----LGRVFNPVwspdGKKIAFT-DNRgrlwvvdLA-----SG 420

                          90       100
                  ....*....|....*....|....*....
gi 485718361  363 EVEYLTENhANPPSADAVVFSPDGQWLAW 391
Cdd:COG4946   421 KVRKVDTD-GYGDGISDLAWSPDSKWLAY 448
COG4946 COG4946
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown] ...
 294-392 1.76e-06

Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown];


Pssm-ID: 443973 [Multi-domain]  Cd Length: 1072  Bit Score: 50.42  E-value: 1.76e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485718361  294 NPQGTQIAFLmrDDNGivQLWLISPQGGEPRQLTHNKTDIQ-SAFNWHPSGEWLGFV--LDN---RIACAHAQSGEVEYL 367
Cdd:COG4946   397 SPDGKKIAFT--DNRG--RLWVVDLASGKVRKVDTDGYGDGiSDLAWSPDSKWLAYSkpGPNqlsQIFLYDVETGKTVQL 472

                          90       100
                  ....*....|....*....|....*
gi 485718361  368 TENHANppsADAVVFSPDGQWLAWM 392
Cdd:COG4946   473 TDGRYD---DGSPAFSPDGKYLYFL 494
WD40 COG2319
WD40 repeat [General function prediction only];
269-390 3.08e-05

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 45.67  E-value: 3.08e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485718361 269 QRRLTFTHHRAypglvnvprhWVRC---NPQGTQIAFLmrDDNGIVQLWliSPQGGEPRQLTHNKTDIQSAFNWHPSGEW 345
Cdd:COG2319  195 KLLRTLTGHTG----------AVRSvafSPDGKLLASG--SADGTVRLW--DLATGKLLRTLTGHSGSVRSVAFSPDGRL 260

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 485718361 346 LGFV-LDNRIACAHAQSGEVEYLTENHANPPSAdaVVFSPDGQWLA 390
Cdd:COG2319  261 LASGsADGTVRLWDLATGELLRTLTGHSGGVNS--VAFSPDGKLLA 304
WD40 COG2319
WD40 repeat [General function prediction only];
269-390 4.15e-05

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 45.29  E-value: 4.15e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485718361 269 QRRLTFTHHRAYPglvnvprHWVRCNPQGTQIAFLMRDdnGIVQLWliSPQGGEPRQLTHNKTDIQSAFNWHPSGEWLGF 348
Cdd:COG2319  237 KLLRTLTGHSGSV-------RSVAFSPDGRLLASGSAD--GTVRLW--DLATGELLRTLTGHSGGVNSVAFSPDGKLLAS 305

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 485718361 349 V-LDNRIACAHAQSGEVEYLTENHANPPSAdaVVFSPDGQWLA 390
Cdd:COG2319  306 GsDDGTVRLWDLATGKLLRTLTGHTGAVRS--VAFSPDGKTLA 346
WD40 COG2319
WD40 repeat [General function prediction only];
269-390 2.78e-04

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 42.98  E-value: 2.78e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485718361 269 QRRLTFTHHRAypglvnvPRHWVRCNPQGTQIAFLMRDdnGIVQLWliSPQGGEPRQLTHNKTDIQSAFNWHPSGEWLGF 348
Cdd:COG2319  279 ELLRTLTGHSG-------GVNSVAFSPDGKLLASGSDD--GTVRLW--DLATGKLLRTLTGHTGAVRSVAFSPDGKTLAS 347

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 485718361 349 V-LDNRIACAHAQSGEVEYLTENHANPPSAdaVVFSPDGQWLA 390
Cdd:COG2319  348 GsDDGTVRLWDLATGELLRTLTGHTGAVTS--VAFSPDGRTLA 388
WD40 COG2319
WD40 repeat [General function prediction only];
287-390 7.43e-04

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 41.44  E-value: 7.43e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485718361 287 PRHWVRC---NPQGTQIAFLmrDDNGIVQLWLISpQGGEPRQLTHNKTDIQSAfNWHPSGEWLGFV-LDNRIACAHAQSG 362
Cdd:COG2319  161 HSGAVTSvafSPDGKLLASG--SDDGTVRLWDLA-TGKLLRTLTGHTGAVRSV-AFSPDGKLLASGsADGTVRLWDLATG 236

                         90       100
                 ....*....|....*....|....*...
gi 485718361 363 EVEYLTENHANPPSAdaVVFSPDGQWLA 390
Cdd:COG2319  237 KLLRTLTGHSGSVRS--VAFSPDGRLLA 262
WD40 COG2319
WD40 repeat [General function prediction only];
247-390 9.93e-04

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 41.05  E-value: 9.93e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485718361 247 AAGDAPLSGTETTLPAPPRGVVQRRLTFTHHRAYPGLVNVPrhwvrcnPQGTQIAFLMRDdnGIVQLWLISpQGGEPRQL 326
Cdd:COG2319   47 DGARLAAGAGDLTLLLLDAAAGALLATLLGHTAAVLSVAFS-------PDGRLLASASAD--GTVRLWDLA-TGLLLRTL 116

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 485718361 327 THNKTDIQSAfNWHPSGEWLGFV-LDNRIACAHAQSGEVEYLTENHANPPSAdaVVFSPDGQWLA 390
Cdd:COG2319  117 TGHTGAVRSV-AFSPDGKTLASGsADGTVRLWDLATGKLLRTLTGHSGAVTS--VAFSPDGKLLA 178
COG4946 COG4946
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown] ...
 292-404 5.77e-03

Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown];


Pssm-ID: 443973 [Multi-domain]  Cd Length: 1072  Bit Score: 38.87  E-value: 5.77e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485718361  292 RCNPQGTQIA-----------FLMRDDNGIV-----QLWLISPQGGEPRQLThnkTDIQSAFNW---------------- 339
Cdd:COG4946   232 SYDPDGKDLRqlthfkdfdvrFPSTDGGRIVyeqggDLYLLDLASGEPRKLN---ITLAGDFPQrrprwvdvsgyltsfa 308

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 485718361  340 -HPSGEWLGFVLDNRIACAHAQSGEveylTENHANPPSADA--VVFSPDGQWLAW--MEGG--QLWITETDR 404
Cdd:COG4946   309 lSPDGKRVAFEARGEVFTVPAEKGP----TRNLTNTPGVRErlPAWSPDGKSIAYfsDASGeyELYIAPADG 376
TolB COG0823
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ...
 13-142 8.11e-03

Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440585 [Multi-domain]  Cd Length: 158  Bit Score: 36.96  E-value: 8.11e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485718361  13 LTNTN------TWTPDSQWLVFDVRPSGasftGETIERVNIHTGEVEVIyrASQGAHVGVVTVHPKSEKYVFIHGPENPD 86
Cdd:COG0823   26 LTNSPgidtspAWSPDGRRIAFTSDRGG----GPQIYVVDADGGEPRRL--TFGGGYNASPSWSPDGKRLAFVSRSDGRF 99

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 485718361  87 ETWHYDfhhrrgviAEGGKVSNLdamdITAPYTPgalrggshvhVFSPNGERVSFT 142
Cdd:COG0823  100 DIYVLD--------LDGGAPRRL----TDGPGSP----------SWSPDGRRIVFS 133
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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