NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|485664084|ref|WP_001305485|]
View 

transcriptional regulator BolA [Escherichia coli]

Protein Classification

BolA family transcriptional regulator( domain architecture ID 10013852)

BolA family transcriptional regulator similar to Escherichia coli protein BolA, which plays an important role in general stress response including heat and osmotic shock, acidic stress, oxidative stress, and carbon-starvation

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
PRK11628 PRK11628
transcriptional regulator BolA; Provisional
 1-104 3.28e-74

transcriptional regulator BolA; Provisional


:

Pssm-ID: 183243  Cd Length: 105  Bit Score: 214.65  E-value: 3.28e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485664084   1 MIRERIEEKLRAAFQPVFLEVVDESYRHNVPAGSESHFKVVLVSDRFTGERFLNRHRMIYSTLAEELSTTVHALALHTYT 80
Cdd:PRK11628   2 MIREQIEEKLRAAFQPVFLEVVDESYRHNVPAGSESHFKVVLVSDRFTGERFLNRHRMIYSTLAEELSTTVHALALHTYT 81

                         90       100
                 ....*....|....*....|....
gi 485664084  81 IKEWEGLQDTVFASPPCRGAGSIA 104
Cdd:PRK11628  82 IKEWEGLQDTVFASPPCRGAGSIA 105
 
Name Accession Description Interval E-value
PRK11628 PRK11628
transcriptional regulator BolA; Provisional
 1-104 3.28e-74

transcriptional regulator BolA; Provisional


Pssm-ID: 183243  Cd Length: 105  Bit Score: 214.65  E-value: 3.28e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485664084   1 MIRERIEEKLRAAFQPVFLEVVDESYRHNVPAGSESHFKVVLVSDRFTGERFLNRHRMIYSTLAEELSTTVHALALHTYT 80
Cdd:PRK11628   2 MIREQIEEKLRAAFQPVFLEVVDESYRHNVPAGSESHFKVVLVSDRFTGERFLNRHRMIYSTLAEELSTTVHALALHTYT 81

                         90       100
                 ....*....|....*....|....
gi 485664084  81 IKEWEGLQDTVFASPPCRGAGSIA 104
Cdd:PRK11628  82 IKEWEGLQDTVFASPPCRGAGSIA 105
BolA COG0271
DNA-binding global transcriptional regulator BolA, affects cell shape, cell division and ...
 1-87 2.54e-45

DNA-binding global transcriptional regulator BolA, affects cell shape, cell division and biofilm formation [Transcription, Signal transduction mechanisms];


Pssm-ID: 440041  Cd Length: 90  Bit Score: 141.09  E-value: 2.54e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485664084   1 MIRERIEEKLRAAFQPVFLEVVDESYRHNVPAG--SESHFKVVLVSDRFTGERFLNRHRMIYSTLAEELSTTVHALALHT 78
Cdd:COG0271    2 SRQERIEEKLTAALAPEHLEVIDESHLHAGHAGagGESHFKVVIVSDAFAGKSRVARHRLVYAALADELAGGIHALAIHA 81


                 ....*....
gi 485664084  79 YTIKEWEGL 87
Cdd:COG0271   82 YTPEEWQAR 90
BolA pfam01722
BolA-like protein; This family consist of the morphoprotein BolA from E. coli and its various ...
 10-83 9.90e-36

BolA-like protein; This family consist of the morphoprotein BolA from E. coli and its various homologs. In E. coli over expression of this protein causes round morphology and may be involved in switching the cell between elongation and septation systems during cell division. The expression of BolA is growth rate regulated and is induced during the transition into the the stationary phase. BolA is also induced by stress during early stages of growth and may have a general role in stress response. It has also been suggested that BolA can induce the transcription of penicillin binding proteins 6 and 5.


Pssm-ID: 460305  Cd Length: 75  Bit Score: 116.40  E-value: 9.90e-36
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 485664084   10 LRAAFQPVFLEVVDESYRHNVPA-GSESHFKVVLVSDRFTGERFLNRHRMIYSTLAEELSTTVHALALHTYTIKE 83
Cdd:pfam01722   1 LTEALAPTHLEVEDESHKHAGHAgGGETHFKVVIVSDAFEGKSLVARHRLVYDALADELAGGIHALSIKTYTPEE 75
 
Name Accession Description Interval E-value
PRK11628 PRK11628
transcriptional regulator BolA; Provisional
 1-104 3.28e-74

transcriptional regulator BolA; Provisional


Pssm-ID: 183243  Cd Length: 105  Bit Score: 214.65  E-value: 3.28e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485664084   1 MIRERIEEKLRAAFQPVFLEVVDESYRHNVPAGSESHFKVVLVSDRFTGERFLNRHRMIYSTLAEELSTTVHALALHTYT 80
Cdd:PRK11628   2 MIREQIEEKLRAAFQPVFLEVVDESYRHNVPAGSESHFKVVLVSDRFTGERFLNRHRMIYSTLAEELSTTVHALALHTYT 81

                         90       100
                 ....*....|....*....|....
gi 485664084  81 IKEWEGLQDTVFASPPCRGAGSIA 104
Cdd:PRK11628  82 IKEWEGLQDTVFASPPCRGAGSIA 105
BolA COG0271
DNA-binding global transcriptional regulator BolA, affects cell shape, cell division and ...
 1-87 2.54e-45

DNA-binding global transcriptional regulator BolA, affects cell shape, cell division and biofilm formation [Transcription, Signal transduction mechanisms];


Pssm-ID: 440041  Cd Length: 90  Bit Score: 141.09  E-value: 2.54e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485664084   1 MIRERIEEKLRAAFQPVFLEVVDESYRHNVPAG--SESHFKVVLVSDRFTGERFLNRHRMIYSTLAEELSTTVHALALHT 78
Cdd:COG0271    2 SRQERIEEKLTAALAPEHLEVIDESHLHAGHAGagGESHFKVVIVSDAFAGKSRVARHRLVYAALADELAGGIHALAIHA 81


                 ....*....
gi 485664084  79 YTIKEWEGL 87
Cdd:COG0271   82 YTPEEWQAR 90
BolA pfam01722
BolA-like protein; This family consist of the morphoprotein BolA from E. coli and its various ...
 10-83 9.90e-36

BolA-like protein; This family consist of the morphoprotein BolA from E. coli and its various homologs. In E. coli over expression of this protein causes round morphology and may be involved in switching the cell between elongation and septation systems during cell division. The expression of BolA is growth rate regulated and is induced during the transition into the the stationary phase. BolA is also induced by stress during early stages of growth and may have a general role in stress response. It has also been suggested that BolA can induce the transcription of penicillin binding proteins 6 and 5.


Pssm-ID: 460305  Cd Length: 75  Bit Score: 116.40  E-value: 9.90e-36
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 485664084   10 LRAAFQPVFLEVVDESYRHNVPA-GSESHFKVVLVSDRFTGERFLNRHRMIYSTLAEELSTTVHALALHTYTIKE 83
Cdd:pfam01722   1 LTEALAPTHLEVEDESHKHAGHAgGGETHFKVVIVSDAFEGKSLVARHRLVYDALADELAGGIHALSIKTYTPEE 75
IbaG COG5007
Acid stress protein IbaG/YrbA, BolA-like family [Signal transduction mechanisms];
1-85 3.00e-16

Acid stress protein IbaG/YrbA, BolA-like family [Signal transduction mechanisms];


Pssm-ID: 444031  Cd Length: 81  Bit Score: 67.10  E-value: 3.00e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485664084   1 MIRERIEEKLRAAFQPVFLEVVdesyrhnvpaGSESHFKVVLVSDRFTGERFLNRHRMIYSTLAEELST-TVHALALHTY 79
Cdd:COG5007    1 MTPEEIKQLIEAGLPCAEVEVE----------GDGSHFEAIVVSDAFEGLSRVKRQQLVYAPLGDYIASgEIHALSIKTY 70


                 ....*.
gi 485664084  80 TIKEWE 85
Cdd:COG5007   71 TPEEWA 76
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH