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Conserved domains on  [gi|481065963|gb|AGK03179|]
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transferrin-binding protein 1 TbpA [Mannheimia haemolytica M42548]

Protein Classification

lactoferrin/transferrin family TonB-dependent receptor( domain architecture ID 11493155)

lactoferrin/transferrin family TonB-dependent receptor similar to Neisseria meningitidis TbpA, an integral outer membrane protein component of the transferrin transport system that promotes iron release from transferrin

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
TonB-tbp-lbp TIGR01776
TonB-dependent lactoferrin and transferrin receptors; This family of TonB-dependent receptors ...
1-930 0e+00

TonB-dependent lactoferrin and transferrin receptors; This family of TonB-dependent receptors are responsible for import of iron from the mammalian iron carriers lactoferrin and transferrin across the outer membrane. These receptors are found only in bacteria which can infect mammals such as Moraxella, Mannheimia, Neisseria, Actinobacillus, Pasteurella, Haemophilus and Histophilus species. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


:

Pssm-ID: 273799 [Multi-domain]  Cd Length: 932  Bit Score: 1411.88  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963    1 MIMKYHHFRYSPVALTVLFALSHsYGAATENKKIEENNDLAVLDEVIVTESHYAHERQNEVTGLGKVVKNYHEMSKNQIL 80
Cdd:TIGR01776   1 MKMKKHVLNLSILALSLLFATLS-FQTADADSAKDTANQAVYLDEITVTATKVAHRRSNEVTGLGKVVKTAETLSKEQVL 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963   81 GIRDLTRYDPGISVVEQGRGASSGYAIRGVDKNRVSLLVDGLPQAQHYHTLGSD---ANGGAINEIEYENIRSIELSKGA 157
Cdd:TIGR01776  80 GIRDLTRYDPGISVVEQGRGASSGYSIRGVDKNRVAVTVDGIPQIQSYTSQGSRsgtAGSGAINEIEYENVRSVEISKGA 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  158 SSAEYGSGALGGAIGFRTKDAQDIIKEGQHWGLDSKTSYASKNSHFLQSIAAAGEAGGFEALVIATHRHGKETKIHSEAN 237
Cdd:TIGR01776 160 NSSEYGSGALGGSVAFRTKDASDIIKPGKHWGLQSKTAYSSKNRHFLQSLAAAGKAGGFEGLVIYTKRRGKETKAHGDAN 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  238 KLKHNIRRITGFENRYDLYPnsaqnaPGGSFFIVEDTCPTLDCTPRARVKLNRDNFpvrtfpeYTPEERKQLEQIPYRTE 317
Cdd:TIGR01776 240 KGVQSIDRLDAFEQKYDLRP------PQGRSFIVENECASLDCAPCAQYGYVYDNQ-------LSDEEKAQVLASRYRHE 306
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  318 QLSAQEYTGKDRIAPNPLDYKSNSVFMKFGYHFNSSHYLGAILEDTKQRYDIRDMQTPAYYTKDDINLSLRNY---VYEG 394
Cdd:TIGR01776 307 QVSAKDYTGENRLLPNPLDYRSDSWLAKLGYHLNNRHYVGGVLEDTKQRYDIRDMTEPAYLGLSDAVKGRLKNgggIYLG 386
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  395 DNILDGLVFK--PRIPYGLRYSHVKFFDERHHKRRLGFTYKYKPEN-NRWLDSIKLSADKQDIELYSRLHRLHCSDYPVV 471
Cdd:TIGR01776 387 DNYLEGLNFNagPASFKGLRYARGKFFDERHTKRRYGLEYRYKNEDyDRWLDTAKLSLDKQKIELRSRLQELHCSQYPKV 466
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  472 DKNCRPTLDKSWSMYRTERNNYQEKHRVIHLEFDKALNAGQGvfkqTHKLNLGLGFDRFNSLMDHGDMTAQYTKGGYTSY 551
Cdd:TIGR01776 467 DKNCRPSLDKPYSFYKNDRNHYKEKHNVIQAEFDKSFDLGGG----RHHLNLLLGYDKFKSQLSRHDYRRQNAVGTYESI 542
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  552 RGRGRLDNPYIYRRDPRSIETVSLCN--NTRGDILNCEPRKIKGDSHFVSFRD-LVISEYVDLGLGVRFDQHRFKSDDPW 628
Cdd:TIGR01776 543 RGDEPKQNPYKYRLGKATIVKNSLCRysETNGYANCCEPRKIKGSNHYISLNDnFTIGKYVDLGLGGRYDKHNFKSTDRL 622
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  629 TLSRTYRNWSWNGGITLKPTEFVSLSYRISNGFRVPAFYELYGKRDHIGLKDNeyVQRAQRSHQLEPEKSTNHEIGVSFK 708
Cdd:TIGR01776 623 VYSGTYRNLSWNFGIVVKPTPFFSLSYRASTGFRVPSFYELYGERRGKASKKN--VQQFLRTPDLKPEKSLNHEIGARFK 700
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  709 GQFGYLDVSYFRNNYKNMIATA-CKRI-----IQKSHCFYNYHNIQDVALNGINLVAKFDLHGILSMLPDGFYSSVAYNR 782
Cdd:TIGR01776 701 GDFGHLEVSYFRNRYKDMIAEApETRTdneagQTYGYCDHNYHNAQNAVLKGINILGKLDLNGVASKLPDGLYSTLAYNR 780
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  783 VKVKERKLTDSRLDsVNDPILDAIQPARYVLGFGYDHPEEKWGIGITTTYSKAKNADEVAGTRHHGIHRVD---LGGKLT 859
Cdd:TIGR01776 781 IKVKEVKNRAGRLD-VRSPLLDAIQPARYVVGLGYDHPSQKWGINLTLTYSKAKNPDELAGTEYLGNGNVVkqtATKKLS 859
                         890       900       910       920       930       940       950
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 481065963  860 GSWYTHDITGYIN-YKNYTLRGGIYNVTNRKYSTWESVRQSGVNAVNQDRG-SNYTRFAAPGRNFSLAFEMKF 930
Cdd:TIGR01776 860 RSWYTLDVTGYVNlKKNLTLRAGVYNLFNYRYTTWESVRQTASNAVNQHTGvSNYNRYAAPGRNYSLSLEMKF 932
 
Name Accession Description Interval E-value
TonB-tbp-lbp TIGR01776
TonB-dependent lactoferrin and transferrin receptors; This family of TonB-dependent receptors ...
1-930 0e+00

TonB-dependent lactoferrin and transferrin receptors; This family of TonB-dependent receptors are responsible for import of iron from the mammalian iron carriers lactoferrin and transferrin across the outer membrane. These receptors are found only in bacteria which can infect mammals such as Moraxella, Mannheimia, Neisseria, Actinobacillus, Pasteurella, Haemophilus and Histophilus species. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273799 [Multi-domain]  Cd Length: 932  Bit Score: 1411.88  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963    1 MIMKYHHFRYSPVALTVLFALSHsYGAATENKKIEENNDLAVLDEVIVTESHYAHERQNEVTGLGKVVKNYHEMSKNQIL 80
Cdd:TIGR01776   1 MKMKKHVLNLSILALSLLFATLS-FQTADADSAKDTANQAVYLDEITVTATKVAHRRSNEVTGLGKVVKTAETLSKEQVL 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963   81 GIRDLTRYDPGISVVEQGRGASSGYAIRGVDKNRVSLLVDGLPQAQHYHTLGSD---ANGGAINEIEYENIRSIELSKGA 157
Cdd:TIGR01776  80 GIRDLTRYDPGISVVEQGRGASSGYSIRGVDKNRVAVTVDGIPQIQSYTSQGSRsgtAGSGAINEIEYENVRSVEISKGA 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  158 SSAEYGSGALGGAIGFRTKDAQDIIKEGQHWGLDSKTSYASKNSHFLQSIAAAGEAGGFEALVIATHRHGKETKIHSEAN 237
Cdd:TIGR01776 160 NSSEYGSGALGGSVAFRTKDASDIIKPGKHWGLQSKTAYSSKNRHFLQSLAAAGKAGGFEGLVIYTKRRGKETKAHGDAN 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  238 KLKHNIRRITGFENRYDLYPnsaqnaPGGSFFIVEDTCPTLDCTPRARVKLNRDNFpvrtfpeYTPEERKQLEQIPYRTE 317
Cdd:TIGR01776 240 KGVQSIDRLDAFEQKYDLRP------PQGRSFIVENECASLDCAPCAQYGYVYDNQ-------LSDEEKAQVLASRYRHE 306
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  318 QLSAQEYTGKDRIAPNPLDYKSNSVFMKFGYHFNSSHYLGAILEDTKQRYDIRDMQTPAYYTKDDINLSLRNY---VYEG 394
Cdd:TIGR01776 307 QVSAKDYTGENRLLPNPLDYRSDSWLAKLGYHLNNRHYVGGVLEDTKQRYDIRDMTEPAYLGLSDAVKGRLKNgggIYLG 386
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  395 DNILDGLVFK--PRIPYGLRYSHVKFFDERHHKRRLGFTYKYKPEN-NRWLDSIKLSADKQDIELYSRLHRLHCSDYPVV 471
Cdd:TIGR01776 387 DNYLEGLNFNagPASFKGLRYARGKFFDERHTKRRYGLEYRYKNEDyDRWLDTAKLSLDKQKIELRSRLQELHCSQYPKV 466
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  472 DKNCRPTLDKSWSMYRTERNNYQEKHRVIHLEFDKALNAGQGvfkqTHKLNLGLGFDRFNSLMDHGDMTAQYTKGGYTSY 551
Cdd:TIGR01776 467 DKNCRPSLDKPYSFYKNDRNHYKEKHNVIQAEFDKSFDLGGG----RHHLNLLLGYDKFKSQLSRHDYRRQNAVGTYESI 542
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  552 RGRGRLDNPYIYRRDPRSIETVSLCN--NTRGDILNCEPRKIKGDSHFVSFRD-LVISEYVDLGLGVRFDQHRFKSDDPW 628
Cdd:TIGR01776 543 RGDEPKQNPYKYRLGKATIVKNSLCRysETNGYANCCEPRKIKGSNHYISLNDnFTIGKYVDLGLGGRYDKHNFKSTDRL 622
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  629 TLSRTYRNWSWNGGITLKPTEFVSLSYRISNGFRVPAFYELYGKRDHIGLKDNeyVQRAQRSHQLEPEKSTNHEIGVSFK 708
Cdd:TIGR01776 623 VYSGTYRNLSWNFGIVVKPTPFFSLSYRASTGFRVPSFYELYGERRGKASKKN--VQQFLRTPDLKPEKSLNHEIGARFK 700
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  709 GQFGYLDVSYFRNNYKNMIATA-CKRI-----IQKSHCFYNYHNIQDVALNGINLVAKFDLHGILSMLPDGFYSSVAYNR 782
Cdd:TIGR01776 701 GDFGHLEVSYFRNRYKDMIAEApETRTdneagQTYGYCDHNYHNAQNAVLKGINILGKLDLNGVASKLPDGLYSTLAYNR 780
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  783 VKVKERKLTDSRLDsVNDPILDAIQPARYVLGFGYDHPEEKWGIGITTTYSKAKNADEVAGTRHHGIHRVD---LGGKLT 859
Cdd:TIGR01776 781 IKVKEVKNRAGRLD-VRSPLLDAIQPARYVVGLGYDHPSQKWGINLTLTYSKAKNPDELAGTEYLGNGNVVkqtATKKLS 859
                         890       900       910       920       930       940       950
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 481065963  860 GSWYTHDITGYIN-YKNYTLRGGIYNVTNRKYSTWESVRQSGVNAVNQDRG-SNYTRFAAPGRNFSLAFEMKF 930
Cdd:TIGR01776 860 RSWYTLDVTGYVNlKKNLTLRAGVYNLFNYRYTTWESVRQTASNAVNQHTGvSNYNRYAAPGRNYSLSLEMKF 932
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
73-930 1.84e-96

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 316.70  E-value: 1.84e-96
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  73 EMSKNQILGIRDLTRYDPGISVVEQGRGASSGYAIRGVDKNRVSLLVDGLPQAqhyhtLGSDANGGAINEIEYENIRSIE 152
Cdd:cd01347    9 DIEKQPATSLADLLRRIPGVSVTRGGGGGGSTISIRGFGPDRTLVLVDGLPLA-----SSNYGRGVDLNTIPPELIERVE 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 153 LSKGASSAEYGSGALGGAIGFRTKDAQDiiKEGQHWGLD--SKTSYASKNSHFLQSIAAAGEaGGFEALVIATHRHGKET 230
Cdd:cd01347   84 VLKGPSSALYGSGAIGGVVNIITKRPTD--EFGGSVTAGygSDNSGSSGGGGFDVSGALADD-GAFGARLYGAYRDGDGT 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 231 KIHSeanklkhnirritgfenrydlypnsaqnapggsffivedtcptldctprarvklnrdnfpvrtfpeytpeerkqle 310
Cdd:cd01347  161 IDGD---------------------------------------------------------------------------- 164
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 311 qipyrteqlsaqeytgkdrIAPNPLDYKSNSVFMKFGYHFNSSHYLGAILEDTKQRYDIRDMQTPAYYTKDDINLSL-RN 389
Cdd:cd01347  165 -------------------GQADDSDEERYNVAGKLDWRPDDDTRLTLDAGYQDQDADGPGGTLPANGTGSSLGGGPsSN 225
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 390 YVYEGDNILDGLVFKPripYGLRYSHvkFFDERHHKRRLGFTYKYKPENNRWLDSIKLSADKqdielysrlhrlhcsdyp 469
Cdd:cd01347  226 TNGDRDWDYRDRYRKR---ASLGLEH--DLNDTGWTLRANLSYSYTDNDGDPLILNGGNNAA------------------ 282
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 470 vvdkncrptldkswsMYRTERNNYQEKHRVIHLEFDKALNAGQGVFKQTHKLNLGLGFDRFNslmdhgdmTAQYTKGGYT 549
Cdd:cd01347  283 ---------------GGDLGRSGYSSERDTTQLGFDAGLNAPFGTGPVAHTLTLGVEYRREE--------LDEKQTALYA 339
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 550 SYRGRgrldnpyiyrrdprsietvslcnntrgdilnceprkikgdshfvsfrdlvISEYVDLGLGVRFDQHRFKSDD--- 626
Cdd:cd01347  340 QDTIE--------------------------------------------------LTDDLTLTLGLRYDHYDQDSKDtia 369
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 627 -PWTLSRTYRNWSWNGGITLKPTEFVSLSYRISNGFRVPAFYELYGKRDHiglkdneYVQRAQRSHQLEPEKSTNHEIGV 705
Cdd:cd01347  370 gGTTAKKSYSHWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELYGGGSH-------GGTAAVGNPNLKPEKSKQYELGL 442
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 706 SFK-GQFGYLDVSYFRNNYKNMIATAckRIIQKSHCFYNYHNIQDVALNGINLVAKFDLHGilsmlPDGFYSSVAYNRVK 784
Cdd:cd01347  443 KYDpGDGLTLSAALFRIDIKNEIVST--PTNTGLGLVTVYVNGGKARIRGVELEASYDLTD-----GLGLTGSYTYTDTE 515
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 785 VKERKltdsrlDSVNDPILDAIQPARYVLGFGYDHPEEKWGIGITTTYSKAKNADEVAGTRhhgihrvdlgGKLTGSWYT 864
Cdd:cd01347  516 VKRTD------GATTGNRLPGIPKHTANLGLDYELPDEGLTAGGGVRYRGKQYADTANGNN----------TVKVPGYTL 579
                        810       820       830       840       850       860
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 481065963 865 HDITGYINY-KNYTLRGGIYNVTNRKYSTWESVrqsgvnavnqdRGSNYTRFAAPGRNFSLAFEMKF 930
Cdd:cd01347  580 VDLSASYQFtKNLTLRLGVNNLFDKDYYTSLSV-----------RGSGLYGYYGPGRTYYLSVSYKF 635
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
43-904 2.87e-43

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 167.70  E-value: 2.87e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  43 LDEVIVTESHyAHERQNEVTGLGKVVkNYHEMSKNQILGIRDLTRYDPGISVvEQGRGASSGYAIRGV--DKNRVSLLVD 120
Cdd:COG1629    1 LEEVVVTATR-TDESLQDVPGSVSVI-SREQLEDQPATDLGDLLRRVPGVSV-TSAGGGAGQISIRGFggGGNRVLVLVD 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 121 GLPQAqhyhtlGSDANGGAINEIEYENIRSIELSKGASSAEYGSGALGGAIGFRTKDAQDiikegqHWGLDSKTSYASkN 200
Cdd:COG1629   78 GVPLN------DPSGGDGGLSYIDPEDIERVEVLRGPSSALYGSGALGGVINIVTKKPKD------GKGGEVSASYGS-Y 144
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 201 SHFLQSIAAAGEAGGFEALVIATHRHGKETKIHSeanklkhnirritgfenrydlypnsaqnapggsffivedtcptldc 280
Cdd:COG1629  145 GTYRASLSLSGGNGKLAYRLSASYRDSDGYRDNS---------------------------------------------- 178
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 281 tprarvklnrdnfpvrtfpeytpeerkqleqipyrteqlsaqeytgkdriapnplDYKSNSVFMKFGYHFNSSHYLGAIL 360
Cdd:COG1629  179 -------------------------------------------------------DSDRYNLRAKLGYQLGDDTRLTLSA 203
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 361 EDTKQRYDirdmqTPAYYTKDdiNLSLRNYVYEGDNildglvfkpriPYGLRYSHVKFfderhhkRRLGFTYKYKPENNR 440
Cdd:COG1629  204 SYSDSDQD-----SPGYLTLA--ALRPRGAMDDGTN-----------PYSNDTDDNTR-------DRYSLSLEYEHLGDG 258
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 441 WldSIKLSADkqdielYSRLHRLHCSDYPVVDKNCRptldkswsmyRTERNNYQEKHRVIHLEFDKALNagqgvFKQTHK 520
Cdd:COG1629  259 L--KLSASAY------YRYDDTDLDSDFTPTPADGG----------TLEQTDFDNRTYGLELRLTYDLG-----FGGKHT 315
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 521 LNLGLGFDRFnslmdhgdmtaQYTKGGYTSYRGRGRLDNPYIYRRDPRSIETVSLcnntrgdilnceprkikgdshFVSF 600
Cdd:COG1629  316 LLVGLDYQRQ-----------DLDGSGYPLDLGSGSLPTLTSGADDDGTTTSLAL---------------------YAQD 363
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 601 rDLVISEYVDLGLGVRFDQHRFKSDDPWT------LSRTYRNWSWNGGITLKPTEFVSLSYRISNGFRVPAFYELYGKRD 674
Cdd:COG1629  364 -TYKLTDKLTLTAGLRYDYVSYDVDDTVTgtdsasGSRSYSAFSPSLGLTYQLSPNLSLYASYSRGFRAPTFGELYANGT 442
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 675 HIGLKDNEyvqraqrshQLEPEKSTNHEIGVSFKGQFGYL--DVSYFRNNYKNMIATACKRIIQKSHCFYNyhNIQDVAL 752
Cdd:COG1629  443 DPYSVGNP---------DLKPETSTNYELGLRYRLLDGRLslSLALFYSDVDNEILSVPLPNDSGFSTYYT--NAGKARS 511
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 753 NGINLVAKFDLHgilsmlpDGFYSSVAYNRVKVKERKLTDSRLDSVNDPiLDAIQPARYVLGFGYDHPeEKWGIGITTTY 832
Cdd:COG1629  512 YGVELELSYQLT-------PGLSLNASYSYTDAKFDDDTDGSADLDGNR-LPGVPPLTANLGLTYEFP-GGWSLGLGVRY 582
                        810       820       830       840       850       860       870
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 481065963 833 SKAKNADEVAGTRHH-GIHRVDLGGkltgswythditGYINYKNYTLRGGIYNVTNRKYSTWESVRQSGVNAV 904
Cdd:COG1629  583 VGDRYLDDANTQGAPgGYTLVDLGA------------GYRFGDNLTLSLGVDNLFDKKYATSLSVRASNVRGF 643
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
417-929 1.05e-36

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 144.91  E-value: 1.05e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  417 KFFDERHHKRRLGFTYKYKPENNRWLDSIKLSADKQDIELYSRLHRLHCSDYPVVDK-----NCRPTLDKSWSMYRTERN 491
Cdd:pfam00593   4 LSLDLLGDDTLLTLGYDYSRYTDGLDLGLTLDGYGNDGGYLGDRPLYYGRDYSDTDRkrlslGYDYDLGDGLSWLSTLRL 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  492 NYQEKHRVIHLEFDKALNAGQGVFKQTHKLNLGLGFDRFNSL---MDHGDMTAQYTKGGYTSYRGRGRLDNPYIYRRDPR 568
Cdd:pfam00593  84 GLRYSSLDGDYTSNSSGLSGAGDYLSDDRLYGLYGLDGDLELsldLSHDLLLGVELRTAGLDYRRLDDDAYDPYDPANPS 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  569 SIETvslcnntrgdilncepRKIKGDSHFVSFRDLV-ISEYVDLGLGVRFDQHRFKSDDPW----TLSRTYRNWSWNGGI 643
Cdd:pfam00593 164 SSSY----------------SDTTTDSYGLYLQDNIkLTDRLTLTLGLRYDHYSTDGDDGNgggdNFSRSYSAFSPRLGL 227
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  644 TLKPTEFVSLSYRISNGFRVPAFYELYGKRDHIGlkdneYVQRAQRSHQLEPEKSTNHEIGVSFKGQFGYLDVSYFRNNY 723
Cdd:pfam00593 228 VYKPTDNLSLYASYSRGFRAPSLGELYGSGSGGG-----GGAVAGGNPDLKPETSDNYELGLKYDDGRLSLSLALFYIDI 302
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  724 KNMIATAcKRIIQKSHCFYNYHNIQDVALNGINLVAKFDLHGILsmlpdGFYSSVAYNRVKVKERKLTDSRLdsvndpiL 803
Cdd:pfam00593 303 KNLITSD-PDGPGLGGTVYTYTNVGKARIRGVELELSGRLWGLG-----LSGGGYTYTDADDDADADDTGNP-------L 369
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  804 DAIQPARYVLGFGYDHPEEKWGIGITTTYSKAKNAdevagtrhhgiHRVDLGGKL-TGSWYTHDIT-GYINYKNYTLRGG 881
Cdd:pfam00593 370 PNVPRHTANLGLTYDFPLGGWGARLGARYVGSGER-----------RYGDAANTFkTPGYTLVDLSaGYRLNKNLTLRLG 438
                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*...
gi 481065963  882 IYNVTNRKYSTWESVrqsgvnavnqdRGSNYTRFAAPGRNFSLAFEMK 929
Cdd:pfam00593 439 VNNLFDKYYKRYYSS-----------GGGNLGGYPGPGRTFYLGLSYK 475
btuB PRK10641
TonB-dependent vitamin B12 receptor BtuB;
84-180 3.37e-07

TonB-dependent vitamin B12 receptor BtuB;


Pssm-ID: 236730 [Multi-domain]  Cd Length: 614  Bit Score: 54.23  E-value: 3.37e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  84 DLTRYDPGISVVEQG-RGASSGYAIRGVDKNRVSLLVDGLPQAQHYHTLGSDanggaINEIEYENIRSIELSKGASSAEY 162
Cdd:PRK10641  64 DVLRRLPGVDIAQNGgLGQLSSLFIRGTNSSHVLVLIDGVRLNQAGISGSAD-----LSQIPISLVQRIEYIRGPRSAVY 138
                         90
                 ....*....|....*...
gi 481065963 163 GSGALGGAIGFRTKDAQD 180
Cdd:PRK10641 139 GSDAIGGVVNIITTRDKP 156
 
Name Accession Description Interval E-value
TonB-tbp-lbp TIGR01776
TonB-dependent lactoferrin and transferrin receptors; This family of TonB-dependent receptors ...
1-930 0e+00

TonB-dependent lactoferrin and transferrin receptors; This family of TonB-dependent receptors are responsible for import of iron from the mammalian iron carriers lactoferrin and transferrin across the outer membrane. These receptors are found only in bacteria which can infect mammals such as Moraxella, Mannheimia, Neisseria, Actinobacillus, Pasteurella, Haemophilus and Histophilus species. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273799 [Multi-domain]  Cd Length: 932  Bit Score: 1411.88  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963    1 MIMKYHHFRYSPVALTVLFALSHsYGAATENKKIEENNDLAVLDEVIVTESHYAHERQNEVTGLGKVVKNYHEMSKNQIL 80
Cdd:TIGR01776   1 MKMKKHVLNLSILALSLLFATLS-FQTADADSAKDTANQAVYLDEITVTATKVAHRRSNEVTGLGKVVKTAETLSKEQVL 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963   81 GIRDLTRYDPGISVVEQGRGASSGYAIRGVDKNRVSLLVDGLPQAQHYHTLGSD---ANGGAINEIEYENIRSIELSKGA 157
Cdd:TIGR01776  80 GIRDLTRYDPGISVVEQGRGASSGYSIRGVDKNRVAVTVDGIPQIQSYTSQGSRsgtAGSGAINEIEYENVRSVEISKGA 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  158 SSAEYGSGALGGAIGFRTKDAQDIIKEGQHWGLDSKTSYASKNSHFLQSIAAAGEAGGFEALVIATHRHGKETKIHSEAN 237
Cdd:TIGR01776 160 NSSEYGSGALGGSVAFRTKDASDIIKPGKHWGLQSKTAYSSKNRHFLQSLAAAGKAGGFEGLVIYTKRRGKETKAHGDAN 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  238 KLKHNIRRITGFENRYDLYPnsaqnaPGGSFFIVEDTCPTLDCTPRARVKLNRDNFpvrtfpeYTPEERKQLEQIPYRTE 317
Cdd:TIGR01776 240 KGVQSIDRLDAFEQKYDLRP------PQGRSFIVENECASLDCAPCAQYGYVYDNQ-------LSDEEKAQVLASRYRHE 306
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  318 QLSAQEYTGKDRIAPNPLDYKSNSVFMKFGYHFNSSHYLGAILEDTKQRYDIRDMQTPAYYTKDDINLSLRNY---VYEG 394
Cdd:TIGR01776 307 QVSAKDYTGENRLLPNPLDYRSDSWLAKLGYHLNNRHYVGGVLEDTKQRYDIRDMTEPAYLGLSDAVKGRLKNgggIYLG 386
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  395 DNILDGLVFK--PRIPYGLRYSHVKFFDERHHKRRLGFTYKYKPEN-NRWLDSIKLSADKQDIELYSRLHRLHCSDYPVV 471
Cdd:TIGR01776 387 DNYLEGLNFNagPASFKGLRYARGKFFDERHTKRRYGLEYRYKNEDyDRWLDTAKLSLDKQKIELRSRLQELHCSQYPKV 466
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  472 DKNCRPTLDKSWSMYRTERNNYQEKHRVIHLEFDKALNAGQGvfkqTHKLNLGLGFDRFNSLMDHGDMTAQYTKGGYTSY 551
Cdd:TIGR01776 467 DKNCRPSLDKPYSFYKNDRNHYKEKHNVIQAEFDKSFDLGGG----RHHLNLLLGYDKFKSQLSRHDYRRQNAVGTYESI 542
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  552 RGRGRLDNPYIYRRDPRSIETVSLCN--NTRGDILNCEPRKIKGDSHFVSFRD-LVISEYVDLGLGVRFDQHRFKSDDPW 628
Cdd:TIGR01776 543 RGDEPKQNPYKYRLGKATIVKNSLCRysETNGYANCCEPRKIKGSNHYISLNDnFTIGKYVDLGLGGRYDKHNFKSTDRL 622
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  629 TLSRTYRNWSWNGGITLKPTEFVSLSYRISNGFRVPAFYELYGKRDHIGLKDNeyVQRAQRSHQLEPEKSTNHEIGVSFK 708
Cdd:TIGR01776 623 VYSGTYRNLSWNFGIVVKPTPFFSLSYRASTGFRVPSFYELYGERRGKASKKN--VQQFLRTPDLKPEKSLNHEIGARFK 700
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  709 GQFGYLDVSYFRNNYKNMIATA-CKRI-----IQKSHCFYNYHNIQDVALNGINLVAKFDLHGILSMLPDGFYSSVAYNR 782
Cdd:TIGR01776 701 GDFGHLEVSYFRNRYKDMIAEApETRTdneagQTYGYCDHNYHNAQNAVLKGINILGKLDLNGVASKLPDGLYSTLAYNR 780
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  783 VKVKERKLTDSRLDsVNDPILDAIQPARYVLGFGYDHPEEKWGIGITTTYSKAKNADEVAGTRHHGIHRVD---LGGKLT 859
Cdd:TIGR01776 781 IKVKEVKNRAGRLD-VRSPLLDAIQPARYVVGLGYDHPSQKWGINLTLTYSKAKNPDELAGTEYLGNGNVVkqtATKKLS 859
                         890       900       910       920       930       940       950
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 481065963  860 GSWYTHDITGYIN-YKNYTLRGGIYNVTNRKYSTWESVRQSGVNAVNQDRG-SNYTRFAAPGRNFSLAFEMKF 930
Cdd:TIGR01776 860 RSWYTLDVTGYVNlKKNLTLRAGVYNLFNYRYTTWESVRQTASNAVNQHTGvSNYNRYAAPGRNYSLSLEMKF 932
TonB-hemlactrns TIGR01786
TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model ...
46-930 0e+00

TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model represents a family of TonB-dependent outer membrane receptor/transporters acting on iron-containing proteins such as hemoglobin, transferrin and lactoferrin. Two subfamily models with a narrower scope are contained within this model, the heme/hemoglobin receptor family protein model (TIGR01785) and the transferrin/lactoferrin receptor family model (TIGR01776). Accessions which score above trusted to this model while not scoring above trusted to the more specific models are most likely to be hemoglobin transporters. Nearly all of the species containing trusted hits to this model have access to hemoglobin, transferrin or lactoferrin or related proteins in their biological niche. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273808 [Multi-domain]  Cd Length: 715  Bit Score: 711.49  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963   46 VIVTESHYAHERQNEVTGLGKVVKNYHEMSKNQILGIRDLTRYDPGISVVEQGRGASSGYAIRGVDKNRVSLLVDGLPQA 125
Cdd:TIGR01786   5 VTATRTADPQRRDLSVTPASVSVISREQLKSQQVRNLRDLLRYEPGVSVVEGGRGGSQGINIRGLDKNRVAVLVDGIRQN 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  126 QHYHtlGSDANGGAINEIEYENIRSIELSKGASSAEYGSGALGGAIGFRTKDAQDIIKEGQHWGLDSKTSYASKNSHFLQ 205
Cdd:TIGR01786  85 TSYG--GQGSTFYAINSIDPELIKSIEIVKGASSSLYGSGALGGVVAFRTKDAADLLKPGKDLGGLSKLGYSSANNRFTQ 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  206 SIAAAGEAGGFEALVIATHRHGKETKIHSEANKLKHnirritgfenrydlypnsaqnapggsffivedtcptldctprar 285
Cdd:TIGR01786 163 SVAAAGRNDDVDALVQATYRRGHELKNGNKANIGNE-------------------------------------------- 198
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  286 vklnrdnfpvrtfpeytpeerkqleqipyrteqlsaqeytgKDRIAPNPLDYKSNSVFMKFGYHFNSSHYLGAILEDTKQ 365
Cdd:TIGR01786 199 -----------------------------------------SKRSKPNPSDYKSQSFLAKLGWQLNDAHRLGLSLEYTQT 237
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  366 RYDIRDMQTPAYYTKDDINLslrnyvyegdnildglvfkpripygLRYSHVKFFDERHHKRRLGFTYKYKPENnRWLDSI 445
Cdd:TIGR01786 238 DYDEPEMTNTSYLTKPLGAP-------------------------LLSSTVVLGDSKTRDRRTGLDYELNPDN-SWLDTV 291
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  446 KLSADKQDIELYSRLHRLHCSDYPVVDKNCRptldkswsmyrternnYQEKHRVIHLEFDKALNAGQGVfkqtHKLNLGL 525
Cdd:TIGR01786 292 KLALDKQYIQLYNYLNATSASDYPGVDKNGR----------------YKDKYDYYTLGFDTNNKIEFSV----HSLSLTY 351
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  526 GFDRFNSLMDHGDMTAQYTKGGYTSYRGRGrldnpyiyrrdprsietvslcnntrgdilncEPRKIKGDSHFVSFRD-LV 604
Cdd:TIGR01786 352 GLDRFKDKVSTGDSRRNLPTAAYNLYGYEG-------------------------------ENRPVKGSNFGLFLQDnIK 400
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  605 ISEYVDLGLGVRFDQHRFK-----SDDPWTLSRTYRNWSWNGGITLKPTEFVSLSYRISNGFRVPAFYELYGKRDHIGLK 679
Cdd:TIGR01786 401 LGDWLSLSAGLRYDHYKTDpkadeSKDYGAISKTYSRWSPSLGLTYKPTPWLTLYYSYSQGFRAPSFDELYGTGAHPGGG 480
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  680 DNEYVqraqRSHQLEPEKSTNHEIGVSFKGQFGYLDVSYFRNNYKNMIATACKRI------IQKSHCFYNYHNIQDVALN 753
Cdd:TIGR01786 481 PYTFL----PNPNLKPETSKNWEIGINLHFDQLDFKVSYFRNDYKDFIDLGIGVTakgnmaQVGSNTITNYVNIDNARIR 556
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  754 GINLVAKFDLHGILSMlPDGFYSSVAYNRVKVKERKltdsrldsvNDPILDAIQPARYVLGFGYDHPEEKWGIGITTTYS 833
Cdd:TIGR01786 557 GIELSGRYDLGSFFSG-PDGWTTTLKYGYTKGKDSD---------TNPWLNAITPLKVVLGLGYDHPDEKWGVGLTLTFS 626
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  834 KAKNADEVAGTRHHGIHRVDLGGKLTGSWYTHDITGYIN-YKNYTLRGGIYNVTNRKYSTWESVRQSGVNAvnqdrgsny 912
Cdd:TIGR01786 627 GAKDAVDAYATYYENGEAAKAGPLRTPSYTVVDLYGYYKpNKNLTLRFGVYNLLDRKYTTWESARQAGPLA--------- 697
                         890
                  ....*....|....*...
gi 481065963  913 TRFAAPGRNFSLAFEMKF 930
Cdd:TIGR01786 698 TGYTAPGRNYKASVEYKF 715
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
73-930 1.84e-96

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 316.70  E-value: 1.84e-96
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  73 EMSKNQILGIRDLTRYDPGISVVEQGRGASSGYAIRGVDKNRVSLLVDGLPQAqhyhtLGSDANGGAINEIEYENIRSIE 152
Cdd:cd01347    9 DIEKQPATSLADLLRRIPGVSVTRGGGGGGSTISIRGFGPDRTLVLVDGLPLA-----SSNYGRGVDLNTIPPELIERVE 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 153 LSKGASSAEYGSGALGGAIGFRTKDAQDiiKEGQHWGLD--SKTSYASKNSHFLQSIAAAGEaGGFEALVIATHRHGKET 230
Cdd:cd01347   84 VLKGPSSALYGSGAIGGVVNIITKRPTD--EFGGSVTAGygSDNSGSSGGGGFDVSGALADD-GAFGARLYGAYRDGDGT 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 231 KIHSeanklkhnirritgfenrydlypnsaqnapggsffivedtcptldctprarvklnrdnfpvrtfpeytpeerkqle 310
Cdd:cd01347  161 IDGD---------------------------------------------------------------------------- 164
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 311 qipyrteqlsaqeytgkdrIAPNPLDYKSNSVFMKFGYHFNSSHYLGAILEDTKQRYDIRDMQTPAYYTKDDINLSL-RN 389
Cdd:cd01347  165 -------------------GQADDSDEERYNVAGKLDWRPDDDTRLTLDAGYQDQDADGPGGTLPANGTGSSLGGGPsSN 225
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 390 YVYEGDNILDGLVFKPripYGLRYSHvkFFDERHHKRRLGFTYKYKPENNRWLDSIKLSADKqdielysrlhrlhcsdyp 469
Cdd:cd01347  226 TNGDRDWDYRDRYRKR---ASLGLEH--DLNDTGWTLRANLSYSYTDNDGDPLILNGGNNAA------------------ 282
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 470 vvdkncrptldkswsMYRTERNNYQEKHRVIHLEFDKALNAGQGVFKQTHKLNLGLGFDRFNslmdhgdmTAQYTKGGYT 549
Cdd:cd01347  283 ---------------GGDLGRSGYSSERDTTQLGFDAGLNAPFGTGPVAHTLTLGVEYRREE--------LDEKQTALYA 339
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 550 SYRGRgrldnpyiyrrdprsietvslcnntrgdilnceprkikgdshfvsfrdlvISEYVDLGLGVRFDQHRFKSDD--- 626
Cdd:cd01347  340 QDTIE--------------------------------------------------LTDDLTLTLGLRYDHYDQDSKDtia 369
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 627 -PWTLSRTYRNWSWNGGITLKPTEFVSLSYRISNGFRVPAFYELYGKRDHiglkdneYVQRAQRSHQLEPEKSTNHEIGV 705
Cdd:cd01347  370 gGTTAKKSYSHWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELYGGGSH-------GGTAAVGNPNLKPEKSKQYELGL 442
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 706 SFK-GQFGYLDVSYFRNNYKNMIATAckRIIQKSHCFYNYHNIQDVALNGINLVAKFDLHGilsmlPDGFYSSVAYNRVK 784
Cdd:cd01347  443 KYDpGDGLTLSAALFRIDIKNEIVST--PTNTGLGLVTVYVNGGKARIRGVELEASYDLTD-----GLGLTGSYTYTDTE 515
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 785 VKERKltdsrlDSVNDPILDAIQPARYVLGFGYDHPEEKWGIGITTTYSKAKNADEVAGTRhhgihrvdlgGKLTGSWYT 864
Cdd:cd01347  516 VKRTD------GATTGNRLPGIPKHTANLGLDYELPDEGLTAGGGVRYRGKQYADTANGNN----------TVKVPGYTL 579
                        810       820       830       840       850       860
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 481065963 865 HDITGYINY-KNYTLRGGIYNVTNRKYSTWESVrqsgvnavnqdRGSNYTRFAAPGRNFSLAFEMKF 930
Cdd:cd01347  580 VDLSASYQFtKNLTLRLGVNNLFDKDYYTSLSV-----------RGSGLYGYYGPGRTYYLSVSYKF 635
TonB-hemin TIGR01785
TonB-dependent heme/hemoglobin receptor family protein; This model represents the ...
43-930 2.47e-53

TonB-dependent heme/hemoglobin receptor family protein; This model represents the TonB-dependent outer membrane heme/hemoglobin receptor/transporter found in bacteria which live in contact with animals (which contain hemoglobin or other heme-bearing globins) or legumes (which contain leghemoglobin). Some species having hits to this model such as Nostoc, Caulobacter and Chlorobium do not have an obvious source of hemoglobin-like proteins in their biological niche and so the possibility exists that they act on some other substance. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273807 [Multi-domain]  Cd Length: 665  Bit Score: 198.00  E-value: 2.47e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963   43 LDEVIVTEshyAHERQNEVTGLGKVVKnyheMSKNQILG-----IRDLTRYDPGISVVEQGRGASSGYAIRGVDKNRVSL 117
Cdd:TIGR01785   1 LDTVTVTA---TRTRQVLSEAPASVSV----ISGEQIESkqannLADALNTVPGVDVTGGGRPPGQSINIRGLQDNRVLV 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  118 LVDGLPQA--QHYHTLGSdanggaiNEIEYENIRSIELSKGASSAEYGSGALGGAIGFRTKDAQDIIKEGQHWGLDSKTS 195
Cdd:TIGR01785  74 VVDGARQNyqRGGAHNGS-------LFVDPELLKRIEIVKGPSSSLYGSGALGGVVAFRTKDAADLLRPGQLFGGLAKLS 146
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  196 YASKNSHFLQSIAAAGEAG-GFEALVIATHRHGketkihseanklkHNIRRITGFEnrydlypnsaqnapggsffivedt 274
Cdd:TIGR01785 147 YGSNNNSFGGSVAVAGRLDdNLDALVAATYRDG-------------GNYRNGNKEE------------------------ 189
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  275 cptldctprarvklnrdnfpvrtfpeytpeerkqleqipyrteqlsaqeytgkdriaPNPLDYKSNSVFMKFGYHFNSSH 354
Cdd:TIGR01785 190 ---------------------------------------------------------ATNSAYVQKNLLAKLGWQLDDAQ 212
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  355 YLGaiLEDTKQRYDIRDMQTPayYTKDDINLSLRNYVYEGDNIldglvfkpripyglRYSHVkffderhhkrrlgFTYKY 434
Cdd:TIGR01785 213 RLE--FSYFTTEGSLDEAQNS--GPGTEYVLGSSSTLLASSTR--------------DRSAT-------------LTYNW 261
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  435 KPENNRWLDSIklsadkqdIELYsrlhrlHCSDYPVVDKNCRPTLDKSWSMYRTERNNYQEKHRvihlefdkalnagqgv 514
Cdd:TIGR01785 262 TPEDNPWLDAT--------ASLY------YNRTENDNDRSARGVGREEGYQYTTYGATLQNTSR---------------- 311
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  515 FKQTHKLNLGLGFDRFNSLMdhgdmtaqytkggyTSYRGRGRLDNPyIYRRDPRSIETVSlcnntrgdilnceprkikgd 594
Cdd:TIGR01785 312 FDVASWSTLTYGVDWMKDKR--------------RTESFDPNSVTT-IVPNPPSAKEYFF-------------------- 356
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  595 SHFVSFRDLVISEYVDLGLGVRFDQHRFKSD---DPWTLSRTYRNWSWNGGITLKPTEFVSLSYRISNGFRVPAFYELYG 671
Cdd:TIGR01785 357 GLFLQDNIPLLDDRLTLSAGLRYDHYKLSPKttaDTEAVDRSYSRWSPSLGLSYKPVDWLTLYASYSQGFRAPSIDELYG 436
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  672 KRDHIGLKD-NEYVQraqrSHQLEPEKSTNHEIG--VSFKGQFGYLD-----VSYFRNNYKNMI---ATACKRIIQKSHC 740
Cdd:TIGR01785 437 TGDHPGTPGgYTFAP----NPNLKPETSKTWELGanLSFDNLLLDNDqlqfkVAYFYNDVKDFIdltIGVTDNVTAGMNN 512
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  741 FYNYHNIQDVALNGINLVAKFDLhgilsmlpDGFYSSVAYNRVKVKerkltdsrlDSVNDPILDAIQPARYVLGFGYDHP 820
Cdd:TIGR01785 513 ITQYVNIDGARIRGIEASASYDA--------GLWATGLSYGYTIGK---------DQNTNQWLSNIPPLKLVVTVGYRFP 575
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  821 EEKWGIGITTTYSKAKN----ADEVAGTrhhgiHRVDlggklTGSWYTHDITGYIN---YKNYTLRGGIYNVTNRKYSTW 893
Cdd:TIGR01785 576 DRRLDLGAKAAYYERQSesptTEDVAAN-----GLLT-----TPGYTVVDLYATYQpnaVKGLTVRFGVNNLTDRKYTPA 645
                         890       900       910
                  ....*....|....*....|....*....|....*..
gi 481065963  894 ESVRQSGvnavnqdrgsnytrfaaPGRNFSLAFEMKF 930
Cdd:TIGR01785 646 QSVPGAG-----------------PGRNFKGSVKYQF 665
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
43-904 2.87e-43

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 167.70  E-value: 2.87e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  43 LDEVIVTESHyAHERQNEVTGLGKVVkNYHEMSKNQILGIRDLTRYDPGISVvEQGRGASSGYAIRGV--DKNRVSLLVD 120
Cdd:COG1629    1 LEEVVVTATR-TDESLQDVPGSVSVI-SREQLEDQPATDLGDLLRRVPGVSV-TSAGGGAGQISIRGFggGGNRVLVLVD 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 121 GLPQAqhyhtlGSDANGGAINEIEYENIRSIELSKGASSAEYGSGALGGAIGFRTKDAQDiikegqHWGLDSKTSYASkN 200
Cdd:COG1629   78 GVPLN------DPSGGDGGLSYIDPEDIERVEVLRGPSSALYGSGALGGVINIVTKKPKD------GKGGEVSASYGS-Y 144
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 201 SHFLQSIAAAGEAGGFEALVIATHRHGKETKIHSeanklkhnirritgfenrydlypnsaqnapggsffivedtcptldc 280
Cdd:COG1629  145 GTYRASLSLSGGNGKLAYRLSASYRDSDGYRDNS---------------------------------------------- 178
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 281 tprarvklnrdnfpvrtfpeytpeerkqleqipyrteqlsaqeytgkdriapnplDYKSNSVFMKFGYHFNSSHYLGAIL 360
Cdd:COG1629  179 -------------------------------------------------------DSDRYNLRAKLGYQLGDDTRLTLSA 203
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 361 EDTKQRYDirdmqTPAYYTKDdiNLSLRNYVYEGDNildglvfkpriPYGLRYSHVKFfderhhkRRLGFTYKYKPENNR 440
Cdd:COG1629  204 SYSDSDQD-----SPGYLTLA--ALRPRGAMDDGTN-----------PYSNDTDDNTR-------DRYSLSLEYEHLGDG 258
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 441 WldSIKLSADkqdielYSRLHRLHCSDYPVVDKNCRptldkswsmyRTERNNYQEKHRVIHLEFDKALNagqgvFKQTHK 520
Cdd:COG1629  259 L--KLSASAY------YRYDDTDLDSDFTPTPADGG----------TLEQTDFDNRTYGLELRLTYDLG-----FGGKHT 315
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 521 LNLGLGFDRFnslmdhgdmtaQYTKGGYTSYRGRGRLDNPYIYRRDPRSIETVSLcnntrgdilnceprkikgdshFVSF 600
Cdd:COG1629  316 LLVGLDYQRQ-----------DLDGSGYPLDLGSGSLPTLTSGADDDGTTTSLAL---------------------YAQD 363
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 601 rDLVISEYVDLGLGVRFDQHRFKSDDPWT------LSRTYRNWSWNGGITLKPTEFVSLSYRISNGFRVPAFYELYGKRD 674
Cdd:COG1629  364 -TYKLTDKLTLTAGLRYDYVSYDVDDTVTgtdsasGSRSYSAFSPSLGLTYQLSPNLSLYASYSRGFRAPTFGELYANGT 442
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 675 HIGLKDNEyvqraqrshQLEPEKSTNHEIGVSFKGQFGYL--DVSYFRNNYKNMIATACKRIIQKSHCFYNyhNIQDVAL 752
Cdd:COG1629  443 DPYSVGNP---------DLKPETSTNYELGLRYRLLDGRLslSLALFYSDVDNEILSVPLPNDSGFSTYYT--NAGKARS 511
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 753 NGINLVAKFDLHgilsmlpDGFYSSVAYNRVKVKERKLTDSRLDSVNDPiLDAIQPARYVLGFGYDHPeEKWGIGITTTY 832
Cdd:COG1629  512 YGVELELSYQLT-------PGLSLNASYSYTDAKFDDDTDGSADLDGNR-LPGVPPLTANLGLTYEFP-GGWSLGLGVRY 582
                        810       820       830       840       850       860       870
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 481065963 833 SKAKNADEVAGTRHH-GIHRVDLGGkltgswythditGYINYKNYTLRGGIYNVTNRKYSTWESVRQSGVNAV 904
Cdd:COG1629  583 VGDRYLDDANTQGAPgGYTLVDLGA------------GYRFGDNLTLSLGVDNLFDKKYATSLSVRASNVRGF 643
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
417-929 1.05e-36

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 144.91  E-value: 1.05e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  417 KFFDERHHKRRLGFTYKYKPENNRWLDSIKLSADKQDIELYSRLHRLHCSDYPVVDK-----NCRPTLDKSWSMYRTERN 491
Cdd:pfam00593   4 LSLDLLGDDTLLTLGYDYSRYTDGLDLGLTLDGYGNDGGYLGDRPLYYGRDYSDTDRkrlslGYDYDLGDGLSWLSTLRL 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  492 NYQEKHRVIHLEFDKALNAGQGVFKQTHKLNLGLGFDRFNSL---MDHGDMTAQYTKGGYTSYRGRGRLDNPYIYRRDPR 568
Cdd:pfam00593  84 GLRYSSLDGDYTSNSSGLSGAGDYLSDDRLYGLYGLDGDLELsldLSHDLLLGVELRTAGLDYRRLDDDAYDPYDPANPS 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  569 SIETvslcnntrgdilncepRKIKGDSHFVSFRDLV-ISEYVDLGLGVRFDQHRFKSDDPW----TLSRTYRNWSWNGGI 643
Cdd:pfam00593 164 SSSY----------------SDTTTDSYGLYLQDNIkLTDRLTLTLGLRYDHYSTDGDDGNgggdNFSRSYSAFSPRLGL 227
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  644 TLKPTEFVSLSYRISNGFRVPAFYELYGKRDHIGlkdneYVQRAQRSHQLEPEKSTNHEIGVSFKGQFGYLDVSYFRNNY 723
Cdd:pfam00593 228 VYKPTDNLSLYASYSRGFRAPSLGELYGSGSGGG-----GGAVAGGNPDLKPETSDNYELGLKYDDGRLSLSLALFYIDI 302
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  724 KNMIATAcKRIIQKSHCFYNYHNIQDVALNGINLVAKFDLHGILsmlpdGFYSSVAYNRVKVKERKLTDSRLdsvndpiL 803
Cdd:pfam00593 303 KNLITSD-PDGPGLGGTVYTYTNVGKARIRGVELELSGRLWGLG-----LSGGGYTYTDADDDADADDTGNP-------L 369
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  804 DAIQPARYVLGFGYDHPEEKWGIGITTTYSKAKNAdevagtrhhgiHRVDLGGKL-TGSWYTHDIT-GYINYKNYTLRGG 881
Cdd:pfam00593 370 PNVPRHTANLGLTYDFPLGGWGARLGARYVGSGER-----------RYGDAANTFkTPGYTLVDLSaGYRLNKNLTLRLG 438
                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*...
gi 481065963  882 IYNVTNRKYSTWESVrqsgvnavnqdRGSNYTRFAAPGRNFSLAFEMK 929
Cdd:pfam00593 439 VNNLFDKYYKRYYSS-----------GGGNLGGYPGPGRTFYLGLSYK 475
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
27-834 2.09e-31

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 131.13  E-value: 2.09e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  27 AATENKKIEEnnDLAVLDEVIVTESHYAHERQNevTGLGKVVKNYHEMSKNQILGIRDLTRYDPGISVVEQ-GRGASSGY 105
Cdd:COG4771   13 AAQAADALAE--DATELEEVVVTATRTEQSLSD--APASVSVITAEEIEKLGATDLADALRLLPGVSVTRSgGRGGSSGI 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 106 AIRGVDKNRVSLLVDGLPQAQhyhtlGSDANGGAINEIEYENIRSIELSKGASSAEYGSGALGGAIGFRTKDAQDIikeg 185
Cdd:COG4771   89 SIRGLGGDRVLVLIDGVPVNN-----PALGGGGDLSYIPPDDIERIEVIRGPASALYGSDAIGGVINIITKKPTDE---- 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 186 qhWGLDSKTSYASKNSHFLQ-SIAAAGEAGGFEALVIATHRHGKETkihseanklkhnirritgfenrydlypnsaqnap 264
Cdd:COG4771  160 --LEGSVSLGYGSNGNGTYSgSLSLGGPGDKLSFLLSGSYRDRDGY---------------------------------- 203
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 265 ggsffivedtcptldctprarvklnrdnfpvrtfpeytpeerkqleqipyrteqlsaqeYTGKDRIAPNPLDYKSNSVFM 344
Cdd:COG4771  204 -----------------------------------------------------------LDYRNGGFVGNSGYERYNLNA 224
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 345 KFGYHFNSSHYLGAILEDTKQRYDIRDMQTPAYYTKDDINLSLRNYVYEGDnildglvfkpripYGLRYSHvkffderhh 424
Cdd:COG4771  225 KLGYRLSDNHRLSLSGGYSRQDRDGGPPTLGDTEISSDNAGDRDTTTDRGN-------------YSLRYNG--------- 282
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 425 krrlgftykykpennRWLDSIKLSADKQDIElysrlhrlhcsdypvvdkncRPTLDKSWSMYRTERNNYQEKHRVIHLEF 504
Cdd:COG4771  283 ---------------DLGDNLDLSLYYSRTD--------------------RDSTNGSLGGSTGSFSDSDDTTYGLELDL 327
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 505 DKALNAGqgvfkqtHKLNLGLGFDrfnslmdhgdmtaqytkggytsyrgRGRLDNPYIYRRDPRSIETVSLcnntrgdil 584
Cdd:COG4771  328 TYPLGGN-------HTLTLGAEYR-------------------------YDDLDSSSFLGGADASRDTYGL--------- 366
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 585 nceprkikgdshFVSFrDLVISEYVDLGLGVRFDQHRFKSDDpwtlsrTYRNWSWNGGITLKPTEFVSLSYRISNGFRVP 664
Cdd:COG4771  367 ------------FAQD-EWKLTDKLTLTAGLRYDYYSTFGAS------NYTAFSPRLGLRYDLSDNLTLRASYGRGFRAP 427
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 665 AFYELYGKRDHIGlkdneyVQRAQRSHQLEPEKSTNHEIGVSFKGQFG--YLDVSYFRNNYKNMIATacKRIIQKSHCFY 742
Cdd:COG4771  428 SLAELYGSGTGTP------GRYVLGNPDLKPETSDNYELGLEYRLGNGglSLSLTGFYTDIKDLIVL--VPVGPGPGDVL 499
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 743 NYHNIQDVALNGINLVAKFDLHGILSmlpdgFYSSVAYNRVKVKERKLTDSrldsvndpiLDAIQPARYVLGFGYDHPEE 822
Cdd:COG4771  500 QYENVGKARTYGLELELKYRLGKGLT-----LTASYTYLDSKIDDGDTGEP---------LPNVPPHKANLGLDYRLPKW 565
                        810
                 ....*....|..
gi 481065963 823 KWGIGITTTYSK 834
Cdd:COG4771  566 WLLLLLTRYYGG 577
Plug pfam07715
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ...
73-170 2.07e-22

TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.


Pssm-ID: 462243 [Multi-domain]  Cd Length: 107  Bit Score: 92.72  E-value: 2.07e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963   73 EMSKNQILGIRDLTRYDPGISVVEQGRGASSGYAIRGVDKNRVSLLVDGLPQAqhyhtlGSDANGGAINEIEYENIRSIE 152
Cdd:pfam07715  16 DIEDQGATNLADALRGVPGVSVSSGGGGGGSSISIRGFGSNRVLVLVDGVPLN------SGGGGSVDLNSIDPEDIERVE 89
                          90
                  ....*....|....*...
gi 481065963  153 LSKGASSAEYGSGALGGA 170
Cdd:pfam07715  90 VLKGPASALYGSGAIGGV 107
FecA COG4772
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
14-930 6.55e-20

Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];


Pssm-ID: 443804 [Multi-domain]  Cd Length: 681  Bit Score: 94.99  E-value: 6.55e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  14 ALTVLFALSHSYGAATEnkkieenndlAVLDEVIVTESHYAHERQNEVTGLGKVVKNyHEMSKNQILGIRDLTRYDPGIS 93
Cdd:COG4772    4 ALAAALLLAAAAAAEAA----------TTLETVVVTGSRAAEARLKDVPGSVSVVDR-EELENQAATSLREVLRRVPGVN 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  94 VV-EQGRGASSGYAIRGVDKNRVS---LLVDGLP---------QAQHYHTLgsdanggaineieyENIRSIELSKGASSA 160
Cdd:COG4772   73 VQeEDGFGLRPNIGIRGLGPRRSRgitLLEDGIPiapapygdpAAYYFPDL--------------ERMERIEVLRGAAAL 138
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 161 EYGSGALGGAIGFRTKDAQDIikegqhWGLDSKTSYASkNSHFLQSIAAAGEAGGFEALVIATHRHGKetkihseanklk 240
Cdd:COG4772  139 RYGPQTVGGAINFVTRTIPTA------FGGELRVTGGS-FGYRRTHASVGGTVGNFGYLVEYSRKRGD------------ 199
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 241 hnirritGFenrydlypnsaqnapggsffivedtcptldctprarvklnRDNfpvrtfpeytpeerkqleqipyrteqlS 320
Cdd:COG4772  200 -------GF----------------------------------------RDN---------------------------S 205
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 321 aqeytgkdriapnplDYKSNSVFMKFGYHFNSSHYLGAILedtkQRYDIrDMQTPAYYTKDDinlslrnyvYEGDnildg 400
Cdd:COG4772  206 ---------------GFDINDFNAKLGYRLSDRQELTLKF----QYYDE-DANTPGGLTDAQ---------FDAD----- 251
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 401 lvfkPRIPYGLRYShvkfFDERHhkRRLGFTYKYKPennrwldsiklsADKQDIEL---YSRLHRLHCSDYPVVDKNCRP 477
Cdd:COG4772  252 ----PRQSYRPADQ----FDTRR--TQLSLRYEHQL------------SDNTTLTTtayYNDFSRNWYIRQNTADPNTPG 309
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 478 TLDKSwsmyrterNNYQEKHRVIHLEFDKALNAGqgvfKQTHKLNLGLgfdRFnslmDHGDMTAQYTKGGYtsyrgrGRL 557
Cdd:COG4772  310 LGLRG--------NPRGYRSYGIEPRLTHRFELG----GVPHTLEVGL---RY----HREEEDRKQYVNTY------GQG 364
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 558 DNPYIYRRDprsietvslcnntrgdilncepRKIKGDSH--FVSFR-----DLVISeyvdlgLGVRFDQHRFKSDD---- 626
Cdd:COG4772  365 RSGAGLRRD----------------------RRFSADALaaYAQNRfeltgRLTLT------PGLRYEHIRRDRTDryst 416
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 627 ----PWTLSRTYRNWSWNGGITLKPTEFVSLSYRISNGFRVPAFYELygkrdhiglkdneyVQRAQRSHQLEPEKSTNHE 702
Cdd:COG4772  417 rtggDDSGSNSYSEFLPGLGLLYQLTDNLQLYANVSRGFEPPTFGDL--------------AYGNGGNPDLKPEKSWNYE 482
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 703 IGVSFK-GQFGYLDVSYFRNNYKNMIATackriIQKSHCFYN-YHNIQDVALNGINLVAKFDLhgiLSMLPDGFYSSVAY 780
Cdd:COG4772  483 LGTRGRiGNGLSAEVALFYIDYDNELGS-----CSAAGGDRStFTNAGETRHQGLELALDYDL---LKGGGLGLPLFAAY 554
                        810       820       830       840       850       860       870       880
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 781 NrvkvkerkLTDSRLDSVNDPI-----LDAIQPARYVLGFGYDHpeEKWGIGITTTYSKAKNADeVAGTRHHGIhrvdlg 855
Cdd:COG4772  555 T--------YTDAEFTSDFGPVfagnrLPYVPRHQLTAGLGYEH--GGWTANLNGRYVSEQFTD-AANTVADGS------ 617
                        890       900       910       920       930       940       950
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 481065963 856 GKLTGSWYTHDIT-GYINYKNYTLRGGIYNVTNRKYSTweSVRqsgvnaVNQDRGsnytRFAAPGRNFSLAFEMKF 930
Cdd:COG4772  618 FGKIPSYTVLDLSaSYDFGKNLSLFAGVNNLFDKRYIA--SRA------PNYAAG----IRPGPPRTVYAGLRLKF 681
BtuB COG4206
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
46-226 6.43e-17

Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];


Pssm-ID: 443355 [Multi-domain]  Cd Length: 276  Bit Score: 81.84  E-value: 6.43e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  46 VIVTESHYAhERQNEVTGLGKVVKNYhEMSKNQILGIRDLTRYDPGISVVEQGR-GASSGYAIRGVDKNRVSLLVDGLPq 124
Cdd:COG4206    1 VVVTATRLE-QSKSDLTGSVTVIDAE-ELERSGATSLADALRRVPGVQVSSSGGpGSAASISIRGLGSNQTLVLIDGVP- 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 125 aqhyhtLGSDANGGA-INEIEYENIRSIELSKGASSAEYGSGALGGAIGFRTKDAqdiiKEGQHWGLDskTSYASKNSHF 203
Cdd:COG4206   78 ------LNDPSLGGVdLSLIPPDDIERIEVLKGAASALYGSDAIGGVINITTKKG----KKGFKGSVS--ASYGSFGTRR 145
                        170       180
                 ....*....|....*....|...
gi 481065963 204 LqSIAAAGEAGGFEALVIATHRH 226
Cdd:COG4206  146 L-SASLSGGAGKFSYSLSASYRR 167
TonB-siderophor TIGR01783
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ...
73-930 7.42e-16

TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273805 [Multi-domain]  Cd Length: 651  Bit Score: 82.08  E-value: 7.42e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963   73 EMSKNQILGIRDLTRYDPGISVVE-QGRGASSGYAIRGVDKN--RVSLLVDGLPQaqhYHTLGSDAnggaineIEYENIR 149
Cdd:TIGR01783  13 ELEDQQAGSLSEALQRVPGVVVGGsGGTTQFGNITIRGFGLEvdIDNVYLDGVPL---LSRGNLAI-------VDPAMVE 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  150 SIELSKGASSAEYGSGALGGAIGFRTKDAQDIIK--EGQHWGLDSktSYASKNSHFLqSIAAAGEAGG---FEALVIATH 224
Cdd:TIGR01783  83 RVEVLRGPASLLYGGSAPGGVINIVTKRPQDEPKgsVTFGAGTRS--GYRTAFDLGG-PLGADGTFRGrlnGARQDGDSF 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  225 RHGKETKIHSEANKLKHNIRRITGFENRYDLYPnSAQNAPGGSFFIVEDTCPtldctPRARVKLNRDNFPVRTFPEYTpE 304
Cdd:TIGR01783 160 YDGAGEETRLGATATDWQLDDRTLLRLGAYYQK-ERDRGGYGGLPASGGTSG-----RDLSSDRYLGTSSNRNYDDRE-Y 232
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  305 ERKQleqipYRTEQLSAQEYTGKDRIAPNPLDYKSNSVFMkfgyhfnsshylGAILEDTKQrydirdmqtpayytkDDIN 384
Cdd:TIGR01783 233 LSYG-----LSLEYQFNDVWTGKQNLRYSYFDTDSNQVQA------------SGYSSDGGL---------------FGRS 280
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  385 LSLRNYVYEGDNILDGLVFKpripyglryshvkfFDERHHKRRLGFTYKYKPENNRWLDSIKLSADKqdielysrlhrlh 464
Cdd:TIGR01783 281 LTVVNVKQDRVQIDAGLDGE--------------FETGPIEHDLLLGVSYGQRTTNRFNNTGYPSDN------------- 333
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  465 cSDYPVVDKNCRPTLDKSWSMYRTErnnyqekhrvihlefdkalnagqgvfkqthklnlglgfdrfnslmdhgdmTAQYT 544
Cdd:TIGR01783 334 -IYSLTATSSARTDIGDSPKDRALS--------------------------------------------------STTKA 362
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  545 KGGYTsyrgrgrldnpyiyrrdprsietvslcnntrgdilncEPRKIKGDShfvsfrdlviseyVDLGLGVRFDQHRFKS 624
Cdd:TIGR01783 363 LNGVA-------------------------------------LQRILLADK-------------WTLTLGGRYDSVDVKS 392
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  625 DDPWTLS---RTYRNWSWNGGITLKPTEFVSLSYRISNGFRVPAFYELYGKRDhiglkdneyvqraqrSHQLEPEKSTNH 701
Cdd:TIGR01783 393 NNGVAGStgkRDDSQFTPSLGVAYKPTDDWSLYASYAESFKPGGYYPKGAGNS---------------GDILEPEKGKNY 457
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  702 EIGVSFKGQFGYL-DVSYFRNNYKNMIATACKRIiqkshcfYNYHNIQDVALNGINLVAKFDLHGILSMlpdgfYSSVAY 780
Cdd:TIGR01783 458 ELGVRYDLGDSLLaTAALFRITKDNQLVQDPVNG-------TFSVNAGKTRNRGVELEARGYLTPGLSL-----SAGYTY 525
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  781 NRVKVKERKLTDSRLDsvndpilDAIQPARYVLGFG--YDHPEEKWGIGITTT--YSKAKNADEVAGTRHHGIHRVDLGg 856
Cdd:TIGR01783 526 TDAEFTEDTNGDTQGN-------TVPFVPKHTASLWasYAPPVGDNGLTLGGGvqYTGKAYVDGGNTGKVPSYTVVDLS- 597
                         810       820       830       840       850       860       870
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 481065963  857 kltGSWythDITgyiNYKNYTLRGGIYNVTNRKYstWESVrqsgvnavnQDRGSNYTRFAAPGRNFSLAFEMKF 930
Cdd:TIGR01783 598 ---VRY---DLT---KKKNLTLALNVNNLFDRDY--YTSG---------YRWGPSAYIYPGAPRTVGLSVSYDF 651
Fiu COG4774
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
78-930 5.17e-14

Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];


Pssm-ID: 443806 [Multi-domain]  Cd Length: 639  Bit Score: 76.07  E-value: 5.17e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  78 QILGIRDLTRYDPGISVVEQGRGASSGYAIRGVDkNRVSLLVDGLPQAQHYHtlgsdanggaineIEYENIRSIELSKGA 157
Cdd:COG4774   25 GATSLADALRNVPGVTFGAGEGGNGDSFSIRGFS-ASGDIYVDGLRDPGQYR-------------RDTFNLERVEVLKGP 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 158 SSAEYGSGALGGAIGFRTKDAQDiikegqhwglDSKTSYAsknshflqsiAAAGEAGGFEALVIATHRHGKETKIhsean 237
Cdd:COG4774   91 ASVLYGRGSPGGVINLVTKRPTD----------EPFTEVT----------LTYGSDGQRRATLDVNGPLGDDLAY----- 145
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 238 klkhnirRITGfenrydlypnSAQNapGGSFfivedtcptldctpRARVKLNRDNfpvrtfpeytpeerkqleqipyrte 317
Cdd:COG4774  146 -------RLNG----------MYRD--SDSY--------------RDGVDNDRWG------------------------- 167
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 318 qlsaqeytgkdrIAPNpLDYKSNSvfmkfgyhfNSSHYLGAILEDTKQRYdirDMQTPAYYTKDDINLSLRNYvyegdni 397
Cdd:COG4774  168 ------------IAPS-LTWRLGD---------RTRLTLDYEYQDDDRTP---DYGVPAVANGRPVDVDRSTF------- 215
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 398 ldglvfkpripYGLRYShvkFFDERHHkrRLGFTYKYKPeNNRWldSIKLSAdkqdieLYSRLHRlhcsDYPVVdkncRP 477
Cdd:COG4774  216 -----------YGQPDD---YSDSETD--SATLRLEHDF-NDNW--TLRNAL------RYSDYDR----DYRNT----YP 262
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 478 TLDKSWSMYRTERNNYQEKHRVIHLEFDkaLNAGQGVFKQTHKLNLGLGFDRFNslmdhgdmtaqYTKGGYTSYRGRGRL 557
Cdd:COG4774  263 TGGNATGTVTRSAYRRDQDNDTLSNQTD--LTGKFDTGGVKHTLLAGVEYSRED-----------SDNARYSGGGTAPTV 329
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 558 DnpyIYrrDPRSIETVSLCNNTRGDilncepRKIKGDSHFVSFRDLV-ISEYVDLGLGVRFDQHRFKSDDPWT----LSR 632
Cdd:COG4774  330 N---LY--NPVYGAPVTGPTLGGAD------NDSRTDTTGLYLQDTIsLTDRWSLLAGLRYDRFDTDYTDRTTgattSSY 398
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 633 TYRNWSWNGGITLKPTEFVSL--SYriSNGFRVPAfyelygkrdhiglkdnEYVQRAQRSHQLEPEKSTNHEIGV---SF 707
Cdd:COG4774  399 DDSAFSPRAGLVYKPTPNLSLyaSY--STSFNPGG----------------GAPSLSNAGQALDPEKSRQYEVGVkwdLL 460
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 708 KGQFGyLDVSYFRNNYKNMIATackriiqkshcfyNYHNIQDVALNGINLVAKFDLhGILSMLPDGF--YSSVAYnrvkv 785
Cdd:COG4774  461 DGRLS-LTAALFRIEKTNVRTT-------------DPANPGVYVQTGEQRSRGVEL-EATGELTPGWsvLAGYTY----- 520
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 786 kerklTDSRLDSVNDPILD---AIQPARYVLGFG--YDHPEEKWGIGITTTYSKAKNADEVAGTRHHGIHRVDLGgkltg 860
Cdd:COG4774  521 -----LDAEITKSANAANVgnrLPNVPRHSASLWttYDLPLPGLTLGGGVRYVGSRYADAANTVKLPSYTRFDAG----- 590
                        810       820       830       840       850       860       870
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 861 swythdiTGYINYKNYTLRGGIYNVTNRKYstWESVRQSGVNAVnqdrgsnytrfaAPGRNFSLAFEMKF 930
Cdd:COG4774  591 -------ASYRLNKNLTLRLNVNNLTDKRY--YASAYGSGYVTP------------GAPRTVLLSASYRF 639
FhuE COG4773
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ...
78-180 7.56e-09

Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];


Pssm-ID: 443805 [Multi-domain]  Cd Length: 692  Bit Score: 59.52  E-value: 7.56e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  78 QILGIRDLTRYDPGISVVEQGRGASSGYAIRGVDKNRVslLVDGLPQaqhyhtlgsdaNGGAINEIEYENIRSIELSKGA 157
Cdd:COG4773   81 GATTLDDALRNVPGVTVSSYDGGGRDSFSIRGFSIDNY--LRDGLPL-----------GGFGGGQPDTANLERVEVLKGP 147
                         90       100
                 ....*....|....*....|...
gi 481065963 158 SSAEYGSGALGGAIGFRTKDAQD 180
Cdd:COG4773  148 AGLLYGAGSPGGLVNLVTKRPTA 170
btuB PRK10641
TonB-dependent vitamin B12 receptor BtuB;
84-180 3.37e-07

TonB-dependent vitamin B12 receptor BtuB;


Pssm-ID: 236730 [Multi-domain]  Cd Length: 614  Bit Score: 54.23  E-value: 3.37e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  84 DLTRYDPGISVVEQG-RGASSGYAIRGVDKNRVSLLVDGLPQAQHYHTLGSDanggaINEIEYENIRSIELSKGASSAEY 162
Cdd:PRK10641  64 DVLRRLPGVDIAQNGgLGQLSSLFIRGTNSSHVLVLIDGVRLNQAGISGSAD-----LSQIPISLVQRIEYIRGPRSAVY 138
                         90
                 ....*....|....*...
gi 481065963 163 GSGALGGAIGFRTKDAQD 180
Cdd:PRK10641 139 GSDAIGGVVNIITTRDKP 156
PRK13524 PRK13524
FepA family TonB-dependent siderophore receptor;
610-727 1.16e-06

FepA family TonB-dependent siderophore receptor;


Pssm-ID: 237410 [Multi-domain]  Cd Length: 744  Bit Score: 52.34  E-value: 1.16e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 610 DLGLGVRFDQHrfksddpwtlSRTYRNWSWNGGITLKPTEFVSLSYRISNGFRVPAFYE------LYGKRD--HIGLKDN 681
Cdd:PRK13524 448 MLTPGLRFDHH----------SIVGNNWSPSLNLSQGLGDDFTLKMGIARAYKAPNLYQtnpnyiLYSKGQgcYASAGNG 517
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 481065963 682 EYVQRaqrSHQLEPEKSTNHEIGVSFKgQFGYL-DVSYFRNNYKNMI 727
Cdd:PRK13524 518 CYLQG---NDDLKAETSVNKEIGLEFK-RDGWLaGLTWFRNDYRNKI 560
PRK10064 PRK10064
catecholate siderophore receptor CirA; Provisional
42-188 5.72e-06

catecholate siderophore receptor CirA; Provisional


Pssm-ID: 236646 [Multi-domain]  Cd Length: 663  Bit Score: 50.27  E-value: 5.72e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  42 VLDEVIVTEShyAHErQNEVTGLGKV-VKNYHEMSKNQILGIRDLTRYDPGISVVEQGRGaSSGYAIRGVDKNRVSLLVD 120
Cdd:PRK10064  29 DGETMVVTAS--AVE-QNLKDAPASIsVITQEDLQRKPVQNLKDVLKEVPGVQLTNEGDN-RKGVSIRGLDSSYTLILID 104
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 481065963 121 GL----PQAQHYHtlgsdaNGGAINEIEYENIRSIELSKGASSAEYGSGALGGAIGFRTKdaqdiiKEGQHW 188
Cdd:PRK10064 105 GKrvnsRNAVFRH------NDFDLNWIPVDAIERIEVVRGPMSSLYGSDALGGVVNIITK------KIGQKW 164
PRK13528 PRK13528
outer membrane receptor FepA; Provisional
614-727 6.26e-06

outer membrane receptor FepA; Provisional


Pssm-ID: 237413 [Multi-domain]  Cd Length: 727  Bit Score: 50.14  E-value: 6.26e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 614 GVRFDQHrfksddpwtlSRTYRNWSWNGGITLKPTEFVSLSYRISNGFRVPAFYE------LYGKRDHIGLKDNEYVQRA 687
Cdd:PRK13528 444 GLRFDYH----------SEFGSNWSPSLNLSQELGDYFKVKAGIARAFKAPNLYQssegylLYSRGNGCPKDITSGGCYL 513
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 481065963 688 QRSHQLEPEKSTNHEIGVSFKGQFGYLDVSYFRNNYKNMI 727
Cdd:PRK13528 514 VGNKNLDPEISVNKEIGLEFTVDDYHASVTYFRNDYQNKI 553
PRK13484 PRK13484
IreA family TonB-dependent siderophore receptor;
3-176 1.18e-05

IreA family TonB-dependent siderophore receptor;


Pssm-ID: 139605 [Multi-domain]  Cd Length: 682  Bit Score: 49.24  E-value: 1.18e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963   3 MKYHHFRYSPVALTVLFALSHSYgAATENKKieenndlavlDEVIVTESHYAHERQNEVTGLgkVVKNYHEMSKNQILGI 82
Cdd:PRK13484   1 MKNKYIIAPGIAVMCSAVISSGY-ASSDKKE----------DTLVVTASGFTQQLRNAPASV--SVITSEQLQKKPVSDL 67
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  83 RDLTRYDPGISVveQGRGASSGYAIRGVDKNRVSLLVDGLPQAQHYhtlgSDANGGAINEIEY----ENIRSIELSKGAS 158
Cdd:PRK13484  68 VDAVKDVEGISI--TGGNEKPDISIRGLSGDYTLILVDGRRQSGRE----SRPNGSGGFEAGFippvEAIERIEVIRGPM 141
                        170
                 ....*....|....*...
gi 481065963 159 SAEYGSGALGGAIGFRTK 176
Cdd:PRK13484 142 SSLYGSDAIGGVINIITK 159
PRK13513 PRK13513
ligand-gated channel protein;
7-211 2.06e-05

ligand-gated channel protein;


Pssm-ID: 184104 [Multi-domain]  Cd Length: 659  Bit Score: 48.23  E-value: 2.06e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963   7 HFRYSPVALTVLFALSHSYGAATENKKIEENNDLavldeVIVTESHYAHERQNEVTGLGKVvknyhemSKNQI--LGIRD 84
Cdd:PRK13513   4 RFRKTHKAALVIAAAISSQAYAAEKTNTATPTDT-----MVVTASGFQQRIQDAPASISVV-------TREQLenKAYRD 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  85 LT---RYDPGisVVEQGRGASSGYAIRGVDKNRVSLLVDGLPQAQHYHTLGSDANGgaineIE------YENIRSIELSK 155
Cdd:PRK13513  72 VTdalKDVPG--VVVTGGGSTSDISIRGMAAKYTLILVDGKRVDTRSTRPNSDGSG-----IEqgwlppLAAIERIEVVR 144
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 481065963 156 GASSAEYGSGALGGAIGFRTKDAQDiikeGQHWGLDSKTSYA-SKNS--HFLQSIAAAG 211
Cdd:PRK13513 145 GPMSSLYGSDAMGGVINIITRKVQK----EWHGSLRADATLQeDSKSgdIFQTNAYASG 199
PRK13486 PRK13486
TonB-dependent receptor;
44-201 3.53e-05

TonB-dependent receptor;


Pssm-ID: 139606 [Multi-domain]  Cd Length: 696  Bit Score: 47.71  E-value: 3.53e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  44 DEVIVTESHYAHERQNEVTGLGkvVKNYHEMSKNQILGIRDLTRYDPGISVvEQGRGASSGY--AIRGVDKNRVSLLVDG 121
Cdd:PRK13486  26 DVMIVSASGYEKKLTNAAASVS--VISQEELQSSQYHDLAEALRSVEGVDV-ESGTGKTGGLeiSIRGMPASYTLILIDG 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963 122 LPQAQhyhtlGSDA--NGGAINEIEY----ENIRSIELSKGASSAEYGSGALGGAIGFRTKDAQDIIKEGQHWGLDSKTS 195
Cdd:PRK13486 103 VRQGG-----SSDVtpNGFSAMNTGFmpplAAIERIEVIRGPMSTLYGSDAMGGVVNIITRKNADKWLSSVNAGLNLQES 177

                 ....*.
gi 481065963 196 YASKNS 201
Cdd:PRK13486 178 NKWGNS 183
PRK13483 PRK13483
ligand-gated channel protein;
14-188 3.41e-04

ligand-gated channel protein;


Pssm-ID: 184080 [Multi-domain]  Cd Length: 660  Bit Score: 44.38  E-value: 3.41e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  14 ALTVLFALSHSYGAATENKKieenndlAVLDEVIVTESHYAHERQNEVTGLGkvVKNYHEMSKNQILGIRDLTRYDPGIS 93
Cdd:PRK13483  11 ALCLLPAVFVTHALAQAAPD-------KTMETVVVTASGYEQQIRDAPASIS--VITREDLENRFYRDLTDALLDVPGVV 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  94 VVeqGRGASSGYAIRGVDKNRVSLLVDGLPQAQHYHTLGSDANGgaineIE------YENIRSIELSKGASSAEYGSGAL 167
Cdd:PRK13483  82 VT--GGGDRTDISLRGMGSQYTLILVDGKRQSSRETRPNSDGPG-----VEqawtppLAAIERIEVIRGPMSSLYGSDAI 154
                        170       180
                 ....*....|....*....|.
gi 481065963 168 GGAIGFRTKdaqdiiKEGQHW 188
Cdd:PRK13483 155 GGVINIITR------KVPNEW 169
PRK13528 PRK13528
outer membrane receptor FepA; Provisional
84-176 8.51e-04

outer membrane receptor FepA; Provisional


Pssm-ID: 237413 [Multi-domain]  Cd Length: 727  Bit Score: 43.21  E-value: 8.51e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  84 DLTRYDPGISVVeqGRGASSGYA------IRGVDKNRVSLLVDGLP----QAQHYHTLGSDANGGAINEIEYENIRSIEL 153
Cdd:PRK13528  72 DIIRKMPGVNLT--GNSASGTRGnnrqidIRGMGPENTLILIDGVPvtsrNSVRYSWRGERDTRGDTNWVPPEMVERIEV 149
                         90       100
                 ....*....|....*....|...
gi 481065963 154 SKGASSAEYGSGALGGAIGFRTK 176
Cdd:PRK13528 150 IRGPAAARYGSGAAGGVVNIITK 172
PRK13524 PRK13524
FepA family TonB-dependent siderophore receptor;
9-180 1.03e-03

FepA family TonB-dependent siderophore receptor;


Pssm-ID: 237410 [Multi-domain]  Cd Length: 744  Bit Score: 42.71  E-value: 1.03e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963   9 RYSPVALTVLFALSHSYGAATENKKIEENNDLAVLDEVIVTEshyahERQNeVTGLGKVVKNYHEMSKNQILG-IRDLTR 87
Cdd:PRK13524   4 KIHSLALLVNLGIYGVAQAAEAEDAKTDDTPASHEDTIVVTA-----AEQN-LQAPGVSTITAEDIRKRPPANdVSEIIR 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 481065963  88 YDPGISVVeqGRGASSGYA------IRGVDKNRVSLLVDGLP----QAQHYHTLGSDANGGAINEIEYENIRSIELSKGA 157
Cdd:PRK13524  78 TMPGVNLT--GNSTSGQRGnnrqidIRGMGPENTLILIDGKPvssrNSVRYGWRGERDTRGDTNWVPPEMIERIEVLRGP 155
                        170       180
                 ....*....|....*....|...
gi 481065963 158 SSAEYGSGALGGAIGFRTKDAQD 180
Cdd:PRK13524 156 AAARYGNGAAGGVVNIITKKPTG 178
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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