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Conserved domains on  [gi|474451934|gb|AGI51012|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Notiomystis cincta]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009572)

NADH dehydrogenase subunit 6 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-172 2.51e-51

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 214424  Cd Length: 174  Bit Score: 161.84  E-value: 2.51e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 474451934   1 MMNFVIFMGLCFVLGGLAVASNPSPYYGVVGLVLGSIAGCGWLVSLGVSFVSLVLVMVYLGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 474451934  81 AWFDWGVVGYGLGMG--VIVAVGVAGLGLSDYSLGAGTVNGGGLLSARSDFCGVAVFYSWGAGLFLIGGWGLLLTLFVVL 158
Cdd:MTH00115  81 AWGDWGVVGYVVGFVlvVVVVGVVVGGLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                        170
                 ....*....|....
gi 474451934 159 ELVRGLSRGAIRAV 172
Cdd:MTH00115 161 ELVRGLSRGALRAF 174
 
Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-172 2.51e-51

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 161.84  E-value: 2.51e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 474451934   1 MMNFVIFMGLCFVLGGLAVASNPSPYYGVVGLVLGSIAGCGWLVSLGVSFVSLVLVMVYLGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 474451934  81 AWFDWGVVGYGLGMG--VIVAVGVAGLGLSDYSLGAGTVNGGGLLSARSDFCGVAVFYSWGAGLFLIGGWGLLLTLFVVL 158
Cdd:MTH00115  81 AWGDWGVVGYVVGFVlvVVVVGVVVGGLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                        170
                 ....*....|....
gi 474451934 159 ELVRGLSRGAIRAV 172
Cdd:MTH00115 161 ELVRGLSRGALRAF 174
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-160 3.65e-10

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 55.20  E-value: 3.65e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 474451934   17 LAVASNPSPYYGVVGLVLGSIAGCGWLVSLGVSFVSLVLVMVYLGGMLVVFVYSVSLAADPYPEAWFDWGVVGYGLGMGV 96
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 474451934   97 IVAVGVAGLGLSDYSLGAGTVNGGGLLSARSDfcGVAVFYSWGaGLFLIGGWGLLLTLFVVLEL 160
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAAAAAPDVGNIEAI--GELLFTDYL-LPFELASVLLLVALVGAIVL 141
 
Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-172 2.51e-51

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 161.84  E-value: 2.51e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 474451934   1 MMNFVIFMGLCFVLGGLAVASNPSPYYGVVGLVLGSIAGCGWLVSLGVSFVSLVLVMVYLGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 474451934  81 AWFDWGVVGYGLGMG--VIVAVGVAGLGLSDYSLGAGTVNGGGLLSARSDFCGVAVFYSWGAGLFLIGGWGLLLTLFVVL 158
Cdd:MTH00115  81 AWGDWGVVGYVVGFVlvVVVVGVVVGGLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                        170
                 ....*....|....
gi 474451934 159 ELVRGLSRGAIRAV 172
Cdd:MTH00115 161 ELVRGLSRGALRAF 174
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-172 3.82e-50

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 158.77  E-value: 3.82e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 474451934   1 MMNFVIFMGLCFVLGGLAVASNPSPYYGVVGLVLGSIAGCGWLVSLGVSFVSLVLVMVYLGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 474451934  81 AWFDWGVVGYGLG--MGVIVAVGVAGLGLSDYSLGaGTVNGGGLLSARSDFCGVAVFYSWGAGLFLIGGWGLLLTLFVVL 158
Cdd:MTH00138  81 SWGSWSVLGYVVGylVGVVLAAGLFWGGWYEGSWV-VVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVL 159

                        170
                 ....*....|....
gi 474451934 159 ELVRGLSRGAIRAV 172
Cdd:MTH00138 160 ELTRGLSRGALRAV 173
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-172 1.41e-48

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 155.01  E-value: 1.41e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 474451934   1 MMNFVIFMGLCFVLGGLAVASNPSPYYGVVGLVLGSIAGCGWLVSLGVSFVSLVLVMVYLGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00065   1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 474451934  81 AWFDWGVVGYGLGMGVIVAVGVAGLGLSDYSLGAGTVNGGGLLSARSDFCGVAVFYSWGAGLFLIGGWGLLLTLFVVLEL 160
Cdd:MTH00065  81 AWGSWSVLVYVLFYLLLLIVGYILFGCNFSLEFLFTNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGWVLLLTLFVVLEV 160

                        170
                 ....*....|..
gi 474451934 161 VRGLSRGAIRAV 172
Cdd:MTH00065 161 TRGLSRGSLRAV 172
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-163 8.28e-24

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 91.79  E-value: 8.28e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 474451934   1 MMNFVIFMGLCFVLGGLAVASNPSPYYGVVGLVLGSIAGCGWLVSLGVSFVSLVLVMVYLGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00109   2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 474451934  81 AWFDWGVVGYGLGMGVIVAVGVAGLGLSDYSLGAGTV----------NGGGLLSARSDFCGVAVFYSWGAGLFLIGGWGL 150
Cdd:MTH00109  82 TWVSNKVVLGALLLGLLMELLLVLYVLKDDEVEVVFNfnglgdwviyDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSL 161

                        170
                 ....*....|...
gi 474451934 151 LLTLFVVLELVRG 163
Cdd:MTH00109 162 FIGVFVIIEITRG 174
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 1-172 1.79e-23

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 90.82  E-value: 1.79e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 474451934   1 MMNFVIFMGLCFVLGGLAVASNPSPYYGVVGLVLGSIAGCGWLVSLGVSFVSLVLVMVYLGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00214   1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 474451934  81 AWFDWGVVGYGLgmgvIVAVGVAGLGLSDYSLGAGTVNGGGLLSARSDFCGVAVFYSWGAGLFLIGGWGLLLTLFVVLEL 160
Cdd:MTH00214  81 SWGGWSVLLFFL----FYLLGLGFVGFYFYGGWEMLSWMGVDEANNLDLSGVSDLYSRGFFLLLLGGVVLFLVLFVVLEL 156

                        170
                 ....*....|..
gi 474451934 161 VRGLSRGAIRAV 172
Cdd:MTH00214 157 VRGLSRGALRVV 168
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 2-171 3.58e-18

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 76.87  E-value: 3.58e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 474451934   2 MNFVIFMgLCFVLGGLAVASNPSPYYGVVGLVLGSIAGCGWLVSLGVSFVSLVLVMVYLGGMLVVFVYSVSLAADPYPea 81
Cdd:MTH00045   1 MVFYLFL-ILMLFGSTLVFYSLSPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYP-- 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 474451934  82 wfdwgvVGYGLGMGVIVAVGVAGLGLSDYSLGAGTVNGGGLLSARSDFCGVAVFYSWGAGLFLIGGWGLLLTLFVVLELV 161
Cdd:MTH00045  78 ------SVSNLGEVLVLSLLLSLWVFISFDNFLELSNNNWSLVSLSDLVGSSELYNSGGLYLLLGGFILLVALVVALVIS 151

                        170
                 ....*....|
gi 474451934 162 RGLSRGAIRA 171
Cdd:MTH00045 152 FGHEYSSLRA 161
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-160 3.65e-10

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 55.20  E-value: 3.65e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 474451934   17 LAVASNPSPYYGVVGLVLGSIAGCGWLVSLGVSFVSLVLVMVYLGGMLVVFVYSVSLAADPYPEAWFDWGVVGYGLGMGV 96
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 474451934   97 IVAVGVAGLGLSDYSLGAGTVNGGGLLSARSDfcGVAVFYSWGaGLFLIGGWGLLLTLFVVLEL 160
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAAAAAPDVGNIEAI--GELLFTDYL-LPFELASVLLLVALVGAIVL 141
ND6 MTH00021
NADH dehydrogenase subunit 6; Validated
 7-73 1.79e-03

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 214401 [Multi-domain]  Cd Length: 188  Bit Score: 37.40  E-value: 1.79e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 474451934   7 FMGLCFVLGGLAVASNPSPYYGVVGLVLGSIAGCGWLVSLGVSFVSLVLVMVYLGGMLVVFVYSVSL 73
Cdd:MTH00021   1 FFSLGIIGSGIMVISALNPVHSIFWLVVVFVNSAVFFILLGLDFLALMFLIIYVGAIAILFLFVIML 67
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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