NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|471270297]
View 

Chain A, Serine Protease Subunit Ns2b, Serine Protease Ns3

Protein Classification

Peptidase_S7 domain-containing protein( domain architecture ID 10469724)

Peptidase_S7 domain-containing protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Peptidase_S7 pfam00949
Peptidase S7, Flavivirus NS3 serine protease; The viral genome is a positive strand RNA that ...
 78-227 2.33e-28

Peptidase S7, Flavivirus NS3 serine protease; The viral genome is a positive strand RNA that encodes a single polyprotein precursor. Processing of the polyprotein precursor into mature proteins is carried out by the host signal peptidase and by NS3 serine protease, which requires NS2B (pfam01002) as a cofactor.


:

Pssm-ID: 395758  Cd Length: 129  Bit Score: 104.06  E-value: 2.33e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 471270297   78 TTTGVYRIMTRGLLGSYQAGAGVMVEGVFHTLWHTTKGAALMSGEGRLDPYWGSVKEDRLCYGGPWKLQHKWNGHdEVQM 157
Cdd:pfam00949   1 LTDGILRFFQSSLLGRSQRGVGVLQEGVFHTMWHPTRGTKLHTQGIKTSPSWASVKQDLVDYGGSWKFQGKWLGE-EYQQ 79

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 471270297  158 IvvepgknvknvqtkpgvfktpEGEIGAVTLDYPTGTSGSPIVDKNGDVIGLYGNGVIMPNGSYISAIVQ 227
Cdd:pfam00949  80 Y---------------------GYGLGITDLNLSSGSSGSLVLNQNKQIVGIYFATVEVDDNSFVVGLAQ 128
 
Name Accession Description Interval E-value
Peptidase_S7 pfam00949
Peptidase S7, Flavivirus NS3 serine protease; The viral genome is a positive strand RNA that ...
 78-227 2.33e-28

Peptidase S7, Flavivirus NS3 serine protease; The viral genome is a positive strand RNA that encodes a single polyprotein precursor. Processing of the polyprotein precursor into mature proteins is carried out by the host signal peptidase and by NS3 serine protease, which requires NS2B (pfam01002) as a cofactor.


Pssm-ID: 395758  Cd Length: 129  Bit Score: 104.06  E-value: 2.33e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 471270297   78 TTTGVYRIMTRGLLGSYQAGAGVMVEGVFHTLWHTTKGAALMSGEGRLDPYWGSVKEDRLCYGGPWKLQHKWNGHdEVQM 157
Cdd:pfam00949   1 LTDGILRFFQSSLLGRSQRGVGVLQEGVFHTMWHPTRGTKLHTQGIKTSPSWASVKQDLVDYGGSWKFQGKWLGE-EYQQ 79

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 471270297  158 IvvepgknvknvqtkpgvfktpEGEIGAVTLDYPTGTSGSPIVDKNGDVIGLYGNGVIMPNGSYISAIVQ 227
Cdd:pfam00949  80 Y---------------------GYGLGITDLNLSSGSSGSLVLNQNKQIVGIYFATVEVDDNSFVVGLAQ 128
 
Name Accession Description Interval E-value
Peptidase_S7 pfam00949
Peptidase S7, Flavivirus NS3 serine protease; The viral genome is a positive strand RNA that ...
 78-227 2.33e-28

Peptidase S7, Flavivirus NS3 serine protease; The viral genome is a positive strand RNA that encodes a single polyprotein precursor. Processing of the polyprotein precursor into mature proteins is carried out by the host signal peptidase and by NS3 serine protease, which requires NS2B (pfam01002) as a cofactor.


Pssm-ID: 395758  Cd Length: 129  Bit Score: 104.06  E-value: 2.33e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 471270297   78 TTTGVYRIMTRGLLGSYQAGAGVMVEGVFHTLWHTTKGAALMSGEGRLDPYWGSVKEDRLCYGGPWKLQHKWNGHdEVQM 157
Cdd:pfam00949   1 LTDGILRFFQSSLLGRSQRGVGVLQEGVFHTMWHPTRGTKLHTQGIKTSPSWASVKQDLVDYGGSWKFQGKWLGE-EYQQ 79

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 471270297  158 IvvepgknvknvqtkpgvfktpEGEIGAVTLDYPTGTSGSPIVDKNGDVIGLYGNGVIMPNGSYISAIVQ 227
Cdd:pfam00949  80 Y---------------------GYGLGITDLNLSSGSSGSLVLNQNKQIVGIYFATVEVDDNSFVVGLAQ 128
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH