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Conserved domains on  [gi|470226939|ref|YP_007624617|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Zanda baudinii]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009572)

NADH dehydrogenase subunit 6 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-172 1.66e-54

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 214424  Cd Length: 174  Bit Score: 169.93  E-value: 1.66e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 470226939   1 MAYFVLFLGVSFILAALAVASNPSPYYGVIGLVLGSIVGCGWLMSLGVSFVSLVLFMVYLGGMLVVFVYSVSLAADPFPQ 80
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 470226939  81 AWGDRRVLVYIVGLALVIVLGSVV--GEWGGGKFGVNTVDSLGVPFVRMDFSGVALFYSCGAVMFVMAGWGLLLTLFVVL 158
Cdd:MTH00115  81 AWGDWGVVGYVVGFVLVVVVVGVVvgGLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                        170
                 ....*....|....
gi 470226939 159 ELVRGLSRGAIRAV 172
Cdd:MTH00115 161 ELVRGLSRGALRAF 174
 
Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-172 1.66e-54

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 169.93  E-value: 1.66e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 470226939   1 MAYFVLFLGVSFILAALAVASNPSPYYGVIGLVLGSIVGCGWLMSLGVSFVSLVLFMVYLGGMLVVFVYSVSLAADPFPQ 80
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 470226939  81 AWGDRRVLVYIVGLALVIVLGSVV--GEWGGGKFGVNTVDSLGVPFVRMDFSGVALFYSCGAVMFVMAGWGLLLTLFVVL 158
Cdd:MTH00115  81 AWGDWGVVGYVVGFVLVVVVVGVVvgGLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                        170
                 ....*....|....
gi 470226939 159 ELVRGLSRGAIRAV 172
Cdd:MTH00115 161 ELVRGLSRGALRAF 174
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-160 6.08e-10

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 54.43  E-value: 6.08e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 470226939   17 LAVASNPSPYYGVIGLVLGSIVGCGWLMSLGVSFVSLVLFMVYLGGMLVVFVYSVSLAADPFPQAWGDRRVLvyIVGLAL 96
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSGLP--LAALLL 78

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 470226939   97 VIVLGSVVGEWGGGKFGVNTVDSLGVPFVRMDFSGVALFYScGAVMFVMAGWGLLLTLFVVLEL 160
Cdd:pfam00499  79 GLLLLALLLLVLLSASLTPAAAAAAPDVGNIEAIGELLFTD-YLLPFELASVLLLVALVGAIVL 141
 
Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-172 1.66e-54

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 169.93  E-value: 1.66e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 470226939   1 MAYFVLFLGVSFILAALAVASNPSPYYGVIGLVLGSIVGCGWLMSLGVSFVSLVLFMVYLGGMLVVFVYSVSLAADPFPQ 80
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 470226939  81 AWGDRRVLVYIVGLALVIVLGSVV--GEWGGGKFGVNTVDSLGVPFVRMDFSGVALFYSCGAVMFVMAGWGLLLTLFVVL 158
Cdd:MTH00115  81 AWGDWGVVGYVVGFVLVVVVVGVVvgGLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                        170
                 ....*....|....
gi 470226939 159 ELVRGLSRGAIRAV 172
Cdd:MTH00115 161 ELVRGLSRGALRAF 174
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-172 1.55e-53

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 167.62  E-value: 1.55e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 470226939   1 MAYFVLFLGVSFILAALAVASNPSPYYGVIGLVLGSIVGCGWLMSLGVSFVSLVLFMVYLGGMLVVFVYSVSLAADPFPQ 80
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 470226939  81 AWGDRRVLVYIVGLALVIVLGSVVGEWGGGKFGVNTVDSLGVPFV-RMDFSGVALFYSCGAVMFVMAGWGLLLTLFVVLE 159
Cdd:MTH00138  81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVlRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                        170
                 ....*....|...
gi 470226939 160 LVRGLSRGAIRAV 172
Cdd:MTH00138 161 LTRGLSRGALRAV 173
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-172 7.37e-50

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 158.09  E-value: 7.37e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 470226939   1 MAYFVLFLGVSFILAALAVASNPSPYYGVIGLVLGSIVGCGWLMSLGVSFVSLVLFMVYLGGMLVVFVYSVSLAADPFPQ 80
Cdd:MTH00065   1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 470226939  81 AWGDRRVLVYIVGLALVIVLGSVVGEWGGGKFGVNTVDSLGVPFVRMDFSGVALFYSCGAVMFVMAGWGLLLTLFVVLEL 160
Cdd:MTH00065  81 AWGSWSVLVYVLFYLLLLIVGYILFGCNFSLEFLFTNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGWVLLLTLFVVLEV 160

                        170
                 ....*....|..
gi 470226939 161 VRGLSRGAIRAV 172
Cdd:MTH00065 161 TRGLSRGSLRAV 172
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-163 1.34e-28

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 104.11  E-value: 1.34e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 470226939   1 MAYFVLFLGVSFILAALAVASNPSPYYGVIGLVLGSIVGCGWLMSLGVSFVSLVLFMVYLGGMLVVFVYSVSLAADPFPQ 80
Cdd:MTH00109   2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 470226939  81 AWGDRRVLVYIVGLALVIVLGSVVGEWGGGKFGVNTV----------DSLGVPFVRMDFSGVALFYSCGAVMFVMAGWGL 150
Cdd:MTH00109  82 TWVSNKVVLGALLLGLLMELLLVLYVLKDDEVEVVFNfnglgdwviyDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSL 161

                        170
                 ....*....|...
gi 470226939 151 LLTLFVVLELVRG 163
Cdd:MTH00109 162 FIGVFVIIEITRG 174
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 1-172 1.47e-25

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 96.21  E-value: 1.47e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 470226939   1 MAYFVLFLGVSFILAALAVASNPSPYYGVIGLVLGSIVGCGWLMSLGVSFVSLVLFMVYLGGMLVVFVYSVSLAADPFPQ 80
Cdd:MTH00214   1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 470226939  81 AWGDRRVLVYIVGLALVIVLGSVVGEWGGGKFGVNTVDSLGvpfvRMDFSGVALFYSCGAVMFVMAGWGLLLTLFVVLEL 160
Cdd:MTH00214  81 SWGGWSVLLFFLFYLLGLGFVGFYFYGGWEMLSWMGVDEAN----NLDLSGVSDLYSRGFFLLLLGGVVLFLVLFVVLEL 156

                        170
                 ....*....|..
gi 470226939 161 VRGLSRGAIRAV 172
Cdd:MTH00214 157 VRGLSRGALRVV 168
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 24-171 6.35e-14

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 65.70  E-value: 6.35e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 470226939  24 SPYYGVIGLVLGSIVGCGWLMSLGVSFVSLVLFMVYLGGMLVVFVYSVSLAADPFPqawgdrrvlvYIVGLALVIVLGSV 103
Cdd:MTH00045  22 SPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYP----------SVSNLGEVLVLSLL 91

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 470226939 104 VGEWGGGKFG--VNTVDSLGVPFVRMDFSGVALFYSCGAVMFVMAGWGLLLTLFVVLELVRGLSRGAIRA 171
Cdd:MTH00045  92 LSLWVFISFDnfLELSNNNWSLVSLSDLVGSSELYNSGGLYLLLGGFILLVALVVALVISFGHEYSSLRA 161
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-160 6.08e-10

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 54.43  E-value: 6.08e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 470226939   17 LAVASNPSPYYGVIGLVLGSIVGCGWLMSLGVSFVSLVLFMVYLGGMLVVFVYSVSLAADPFPQAWGDRRVLvyIVGLAL 96
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSGLP--LAALLL 78

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 470226939   97 VIVLGSVVGEWGGGKFGVNTVDSLGVPFVRMDFSGVALFYScGAVMFVMAGWGLLLTLFVVLEL 160
Cdd:pfam00499  79 GLLLLALLLLVLLSASLTPAAAAAAPDVGNIEAIGELLFTD-YLLPFELASVLLLVALVGAIVL 141
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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