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Conserved domains on  [gi|4689316|gb|AAD27848|]
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peroxisomal targeting signal type 2 receptor [Arabidopsis thaliana]

Protein Classification

WD40 repeat domain-containing protein( domain architecture ID 11455410)

WD40 repeat domain-containing protein similar to proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly

CATH:  2.130.10.10
PubMed:  10322433|8090199
SCOP:  4002744

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
37-308 8.88e-42

WD40 repeat [General function prediction only];


:

Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 149.29  E-value: 8.88e-42
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4689316   37 GRIHVLELAPGAPGVTesvSYDTADAVYDVCWSEShDSVLIAANGDGSVKIYDTAlppPSNPIRSFQEHAREVQSVDYNP 116
Cdd:COG2319 100 GTVRLWDLATGLLLRT---LTGHTGAVRSVAFSPD-GKTLASGSADGTVRLWDLA---TGKLLRTLTGHSGAVTSVAFSP 172

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4689316  117 TRRdSFLTSSWDDTVKLWAMDRPASVRTFKEHAYCVYQAVWNPkHGDVFASASGDCTLRIWDVREPGSTMIIPAHDFEIL 196
Cdd:COG2319 173 DGK-LLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSP-DGKLLASGSADGTVRLWDLATGKLLRTLTGHSGSVR 250

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4689316  197 SCDWNKyDDCILATSSVDKTVKVWDVRSYRvPLAVLNGHGYAVRKVKFSPHRRsLIASCSYDMSVCLWDyMVEDALVGRY 276
Cdd:COG2319 251 SVAFSP-DGRLLASGSADGTVRLWDLATGE-LLRTLTGHSGGVNSVAFSPDGK-LLASGSDDGTVRLWD-LATGKLLRTL 326

                       250       260       270
                ....*....|....*....|....*....|..
gi 4689316  277 DHHTEFAVGIDMSVlVEGLMASTGWDELVYVW 308
Cdd:COG2319 327 TGHTGAVRSVAFSP-DGKTLASGSDDGTVRLW 357
 
Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
37-308 8.88e-42

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 149.29  E-value: 8.88e-42
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4689316   37 GRIHVLELAPGAPGVTesvSYDTADAVYDVCWSEShDSVLIAANGDGSVKIYDTAlppPSNPIRSFQEHAREVQSVDYNP 116
Cdd:COG2319 100 GTVRLWDLATGLLLRT---LTGHTGAVRSVAFSPD-GKTLASGSADGTVRLWDLA---TGKLLRTLTGHSGAVTSVAFSP 172

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4689316  117 TRRdSFLTSSWDDTVKLWAMDRPASVRTFKEHAYCVYQAVWNPkHGDVFASASGDCTLRIWDVREPGSTMIIPAHDFEIL 196
Cdd:COG2319 173 DGK-LLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSP-DGKLLASGSADGTVRLWDLATGKLLRTLTGHSGSVR 250

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4689316  197 SCDWNKyDDCILATSSVDKTVKVWDVRSYRvPLAVLNGHGYAVRKVKFSPHRRsLIASCSYDMSVCLWDyMVEDALVGRY 276
Cdd:COG2319 251 SVAFSP-DGRLLASGSADGTVRLWDLATGE-LLRTLTGHSGGVNSVAFSPDGK-LLASGSDDGTVRLWD-LATGKLLRTL 326

                       250       260       270
                ....*....|....*....|....*....|..
gi 4689316  277 DHHTEFAVGIDMSVlVEGLMASTGWDELVYVW 308
Cdd:COG2319 327 TGHTGAVRSVAFSP-DGKTLASGSDDGTVRLW 357
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 11-309 1.63e-36

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 132.46  E-value: 1.63e-36
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4689316   11 YSVKFSPfYESRLAVATaqnfgilGNGRIHVLELAPGAPGVTESVSYDTADAVYDVCWSEShdsvLIAANGDGSVKIYDT 90
Cdd:cd00200  13 TCVAFSP-DGKLLATGS-------GDGTIKVWDLETGELLRTLKGHTGPVRDVAASADGTY----LASGSSDKTIRLWDL 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4689316   91 ALPppsNPIRSFQEHAREVQSVDYNPTRRdSFLTSSWDDTVKLWAMDRPASVRTFKEHAYCVYQAVWNPkHGDVFASASG 170
Cdd:cd00200  81 ETG---ECVRTLTGHTSYVSSVAFSPDGR-ILSSSSRDKTIKVWDVETGKCLTTLRGHTDWVNSVAFSP-DGTFVASSSQ 155

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4689316  171 DCTLRIWDVREPGSTMIIPAHDFEILSCDWNKyDDCILATSSVDKTVKVWDVRSYRVpLAVLNGHGYAVRKVKFSPHRRs 250
Cdd:cd00200 156 DGTIKLWDLRTGKCVATLTGHTGEVNSVAFSP-DGEKLLSSSSDGTIKLWDLSTGKC-LGTLRGHENGVNSVAFSPDGY- 232

                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 4689316  251 LIASCSYDMSVCLWDYMVEDaLVGRYDHHTEFAVGIDMSvLVEGLMASTGWDELVYVWQ 309
Cdd:cd00200 233 LLASGSEDGTIRVWDLRTGE-CVQTLSGHTNSVTSLAWS-PDGKRLASGSADGTIRIWD 289
PLN00181 PLN00181
protein SPA1-RELATED; Provisional
 66-235 1.30e-12

protein SPA1-RELATED; Provisional


Pssm-ID: 177776 [Multi-domain]  Cd Length: 793  Bit Score: 68.19  E-value: 1.30e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4689316    66 VCWSESHDSVLIAANGDGSVKIYDTAlppPSNPIRSFQEHAREVQSVDYNPTRRDSFLTSSWDDTVKLWAMDRPASVRTF 145
Cdd:PLN00181 538 ICWNSYIKSQVASSNFEGVVQVWDVA---RSQLVTEMKEHEKRVWSIDYSSADPTLLASGSDDGSVKLWSINQGVSIGTI 614

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4689316   146 KEHA-YCVYQavWNPKHGDVFASASGDCTLRIWDVREPG---STMIipAHDFEIlscDWNKY-DDCILATSSVDKTVKVW 220
Cdd:PLN00181 615 KTKAnICCVQ--FPSESGRSLAFGSADHKVYYYDLRNPKlplCTMI--GHSKTV---SYVRFvDSSTLVSSSTDNTLKLW 687

                        170       180
                 ....*....|....*....|
gi 4689316   221 DVRSY-----RVPLAVLNGH 235
Cdd:PLN00181 688 DLSMSisginETPLHSFMGH 707
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 228-265 8.21e-06

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 42.30  E-value: 8.21e-06
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 4689316     228 PLAVLNGHGYAVRKVKFSPHRRsLIASCSYDMSVCLWD 265
Cdd:smart00320   4 LLKTLKGHTGPVTSVAFSPDGK-YLASGSDDGTIKLWD 40
WD40 pfam00400
WD domain, G-beta repeat;
228-265 3.08e-05

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 40.41  E-value: 3.08e-05
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 4689316    228 PLAVLNGHGYAVRKVKFSPHRRsLIASCSYDMSVCLWD 265
Cdd:pfam00400   3 LLKTLEGHTGSVTSLAFSPDGK-LLASGSDDGTVKVWD 39
 
Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
37-308 8.88e-42

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 149.29  E-value: 8.88e-42
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4689316   37 GRIHVLELAPGAPGVTesvSYDTADAVYDVCWSEShDSVLIAANGDGSVKIYDTAlppPSNPIRSFQEHAREVQSVDYNP 116
Cdd:COG2319 100 GTVRLWDLATGLLLRT---LTGHTGAVRSVAFSPD-GKTLASGSADGTVRLWDLA---TGKLLRTLTGHSGAVTSVAFSP 172

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4689316  117 TRRdSFLTSSWDDTVKLWAMDRPASVRTFKEHAYCVYQAVWNPkHGDVFASASGDCTLRIWDVREPGSTMIIPAHDFEIL 196
Cdd:COG2319 173 DGK-LLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSP-DGKLLASGSADGTVRLWDLATGKLLRTLTGHSGSVR 250

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4689316  197 SCDWNKyDDCILATSSVDKTVKVWDVRSYRvPLAVLNGHGYAVRKVKFSPHRRsLIASCSYDMSVCLWDyMVEDALVGRY 276
Cdd:COG2319 251 SVAFSP-DGRLLASGSADGTVRLWDLATGE-LLRTLTGHSGGVNSVAFSPDGK-LLASGSDDGTVRLWD-LATGKLLRTL 326

                       250       260       270
                ....*....|....*....|....*....|..
gi 4689316  277 DHHTEFAVGIDMSVlVEGLMASTGWDELVYVW 308
Cdd:COG2319 327 TGHTGAVRSVAFSP-DGKTLASGSDDGTVRLW 357
WD40 COG2319
WD40 repeat [General function prediction only];
11-309 1.21e-39

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 143.51  E-value: 1.21e-39
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4689316   11 YSVKFSPFyESRLAVATAqnfgilgNGRIHVLELAPGAPGVTESvsyDTADAVYDVCWSesHDSVLIA-ANGDGSVKIYD 89
Cdd:COG2319 124 RSVAFSPD-GKTLASGSA-------DGTVRLWDLATGKLLRTLT---GHSGAVTSVAFS--PDGKLLAsGSDDGTVRLWD 190

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4689316   90 TAlppPSNPIRSFQEHAREVQSVDYNPTRRdSFLTSSWDDTVKLWAMDRPASVRTFKEHAYCVYQAVWNPKhGDVFASAS 169
Cdd:COG2319 191 LA---TGKLLRTLTGHTGAVRSVAFSPDGK-LLASGSADGTVRLWDLATGKLLRTLTGHSGSVRSVAFSPD-GRLLASGS 265

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4689316  170 GDCTLRIWDVREPGSTMIIPAHDFEILSCDWNKyDDCILATSSVDKTVKVWDVRSYRvPLAVLNGHGYAVRKVKFSPHRR 249
Cdd:COG2319 266 ADGTVRLWDLATGELLRTLTGHSGGVNSVAFSP-DGKLLASGSDDGTVRLWDLATGK-LLRTLTGHTGAVRSVAFSPDGK 343

                       250       260       270       280       290       300
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 4689316  250 sLIASCSYDMSVCLWDyMVEDALVGRYDHHTEFAVGIDMSVlvEG-LMASTGWDELVYVWQ 309
Cdd:COG2319 344 -TLASGSDDGTVRLWD-LATGELLRTLTGHTGAVTSVAFSP--DGrTLASGSADGTVRLWD 400
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 11-309 1.63e-36

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 132.46  E-value: 1.63e-36
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4689316   11 YSVKFSPfYESRLAVATaqnfgilGNGRIHVLELAPGAPGVTESVSYDTADAVYDVCWSEShdsvLIAANGDGSVKIYDT 90
Cdd:cd00200  13 TCVAFSP-DGKLLATGS-------GDGTIKVWDLETGELLRTLKGHTGPVRDVAASADGTY----LASGSSDKTIRLWDL 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4689316   91 ALPppsNPIRSFQEHAREVQSVDYNPTRRdSFLTSSWDDTVKLWAMDRPASVRTFKEHAYCVYQAVWNPkHGDVFASASG 170
Cdd:cd00200  81 ETG---ECVRTLTGHTSYVSSVAFSPDGR-ILSSSSRDKTIKVWDVETGKCLTTLRGHTDWVNSVAFSP-DGTFVASSSQ 155

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4689316  171 DCTLRIWDVREPGSTMIIPAHDFEILSCDWNKyDDCILATSSVDKTVKVWDVRSYRVpLAVLNGHGYAVRKVKFSPHRRs 250
Cdd:cd00200 156 DGTIKLWDLRTGKCVATLTGHTGEVNSVAFSP-DGEKLLSSSSDGTIKLWDLSTGKC-LGTLRGHENGVNSVAFSPDGY- 232

                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 4689316  251 LIASCSYDMSVCLWDYMVEDaLVGRYDHHTEFAVGIDMSvLVEGLMASTGWDELVYVWQ 309
Cdd:cd00200 233 LLASGSEDGTIRVWDLRTGE-CVQTLSGHTNSVTSLAWS-PDGKRLASGSADGTIRIWD 289
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 98-282 1.16e-31

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 119.75  E-value: 1.16e-31
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4689316   98 PIRSFQEHAREVQSVDYNPTRrDSFLTSSWDDTVKLWAMDRPASVRTFKEHAYCVYQAVWNPkHGDVFASASGDCTLRIW 177
Cdd:cd00200   1 LRRTLKGHTGGVTCVAFSPDG-KLLATGSGDGTIKVWDLETGELLRTLKGHTGPVRDVAASA-DGTYLASGSSDKTIRLW 78

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4689316  178 DVREPGSTMIIPAHDFEILSCDWNKYDDcILATSSVDKTVKVWDVRSYRvPLAVLNGHGYAVRKVKFSPHRRsLIASCSY 257
Cdd:cd00200  79 DLETGECVRTLTGHTSYVSSVAFSPDGR-ILSSSSRDKTIKVWDVETGK-CLTTLRGHTDWVNSVAFSPDGT-FVASSSQ 155

                       170       180
                ....*....|....*....|....*
gi 4689316  258 DMSVCLWDyMVEDALVGRYDHHTEF 282
Cdd:cd00200 156 DGTIKLWD-LRTGKCVATLTGHTGE 179
WD40 COG2319
WD40 repeat [General function prediction only];
11-224 2.86e-28

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 112.70  E-value: 2.86e-28
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4689316   11 YSVKFSPFyESRLAVATAqnfgilgNGRIHVLELAPGAPGVTESvsyDTADAVYDVCWSesHDSVLIA-ANGDGSVKIYD 89
Cdd:COG2319 208 RSVAFSPD-GKLLASGSA-------DGTVRLWDLATGKLLRTLT---GHSGSVRSVAFS--PDGRLLAsGSADGTVRLWD 274

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4689316   90 TAlppPSNPIRSFQEHAREVQSVDYNPTRRdSFLTSSWDDTVKLWAMDRPASVRTFKEHAYCVYQAVWNPKhGDVFASAS 169
Cdd:COG2319 275 LA---TGELLRTLTGHSGGVNSVAFSPDGK-LLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPD-GKTLASGS 349

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*
gi 4689316  170 GDCTLRIWDVREPGSTMIIPAHDFEILSCDWNKyDDCILATSSVDKTVKVWDVRS 224
Cdd:COG2319 350 DDGTVRLWDLATGELLRTLTGHTGAVTSVAFSP-DGRTLASGSADGTVRLWDLAT 403
WD40 COG2319
WD40 repeat [General function prediction only];
99-308 1.62e-22

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 96.90  E-value: 1.62e-22
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4689316   99 IRSFQEHAREVQSVDYNPTRRDSfLTSSWDDTVKLWAMDRPASVRTFKEHAYCVYQAVWNPkHGDVFASASGDCTLRIWD 178
Cdd:COG2319  29 LLLLLGLAAAVASLAASPDGARL-AAGAGDLTLLLLDAAAGALLATLLGHTAAVLSVAFSP-DGRLLASASADGTVRLWD 106

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4689316  179 VREPGSTMIIPAHDFEILSCDWNKyDDCILATSSVDKTVKVWDVRSYRvPLAVLNGHGYAVRKVKFSPHRRsLIASCSYD 258
Cdd:COG2319 107 LATGLLLRTLTGHTGAVRSVAFSP-DGKTLASGSADGTVRLWDLATGK-LLRTLTGHSGAVTSVAFSPDGK-LLASGSDD 183

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|.
gi 4689316  259 MSVCLWDyMVEDALVGRYDHHTEFAVGIDMSvlVEG-LMASTGWDELVYVW 308
Cdd:COG2319 184 GTVRLWD-LATGKLLRTLTGHTGAVRSVAFS--PDGkLLASGSADGTVRLW 231
PLN00181 PLN00181
protein SPA1-RELATED; Provisional
 66-235 1.30e-12

protein SPA1-RELATED; Provisional


Pssm-ID: 177776 [Multi-domain]  Cd Length: 793  Bit Score: 68.19  E-value: 1.30e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4689316    66 VCWSESHDSVLIAANGDGSVKIYDTAlppPSNPIRSFQEHAREVQSVDYNPTRRDSFLTSSWDDTVKLWAMDRPASVRTF 145
Cdd:PLN00181 538 ICWNSYIKSQVASSNFEGVVQVWDVA---RSQLVTEMKEHEKRVWSIDYSSADPTLLASGSDDGSVKLWSINQGVSIGTI 614

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4689316   146 KEHA-YCVYQavWNPKHGDVFASASGDCTLRIWDVREPG---STMIipAHDFEIlscDWNKY-DDCILATSSVDKTVKVW 220
Cdd:PLN00181 615 KTKAnICCVQ--FPSESGRSLAFGSADHKVYYYDLRNPKlplCTMI--GHSKTV---SYVRFvDSSTLVSSSTDNTLKLW 687

                        170       180
                 ....*....|....*....|
gi 4689316   221 DVRSY-----RVPLAVLNGH 235
Cdd:PLN00181 688 DLSMSisginETPLHSFMGH 707
PLN00181 PLN00181
protein SPA1-RELATED; Provisional
 108-311 2.97e-09

protein SPA1-RELATED; Provisional


Pssm-ID: 177776 [Multi-domain]  Cd Length: 793  Bit Score: 58.17  E-value: 2.97e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4689316   108 EVQSVDYNPTRRDSFLTSSWDDTVKLWAMDRPASVRTFKEHAYCVYQAVWNPKHGDVFASASGDCTLRIWDVREPGSTMI 187
Cdd:PLN00181 534 KLSGICWNSYIKSQVASSNFEGVVQVWDVARSQLVTEMKEHEKRVWSIDYSSADPTLLASGSDDGSVKLWSINQGVSIGT 613

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4689316   188 IPAHDfEILSCDWNKYDDCILATSSVDKTVKVWDVRSYRVPLAVLNGHGYAVRKVKFSPhrRSLIASCSYDMSVCLWDYM 267
Cdd:PLN00181 614 IKTKA-NICCVQFPSESGRSLAFGSADHKVYYYDLRNPKLPLCTMIGHSKTVSYVRFVD--SSTLVSSSTDNTLKLWDLS 690

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 4689316   268 -----VEDALVGRYDHHTEFAVGIDMSVlVEGLMASTGWDELVYVWQQG 311
Cdd:PLN00181 691 msisgINETPLHSFMGHTNVKNFVGLSV-SDGYIATGSETNEVFVYHKA 738
PTZ00420 PTZ00420
coronin; Provisional
 138-222 2.46e-07

coronin; Provisional


Pssm-ID: 240412 [Multi-domain]  Cd Length: 568  Bit Score: 51.87  E-value: 2.46e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4689316   138 RPASVRTFKEHAYCVYQAVWNPKHGDVFASASGDCTLRIWDVREPGSTM--------IIPAHDFEILSCDWNKYDDCILA 209
Cdd:PTZ00420  63 RKPPVIKLKGHTSSILDLQFNPCFSEILASGSEDLTIRVWEIPHNDESVkeikdpqcILKGHKKKISIIDWNPMNYYIMC 142

                         90
                 ....*....|...
gi 4689316   210 TSSVDKTVKVWDV 222
Cdd:PTZ00420 143 SSGFDSFVNIWDI 155
PTZ00421 PTZ00421
coronin; Provisional
 94-227 3.45e-07

coronin; Provisional


Pssm-ID: 173611 [Multi-domain]  Cd Length: 493  Bit Score: 51.43  E-value: 3.45e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4689316    94 PPSNPIRSFQEHarEVQSVDYNPTRRDSFLTSSWDDTVKLWamDRPASVRT---------FKEHAYCVYQAVWNPKHGDV 164
Cdd:PTZ00421  65 ASNPPILLGQEG--PIIDVAFNPFDPQKLFTASEDGTIMGW--GIPEEGLTqnisdpivhLQGHTKKVGIVSFHPSAMNV 140

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 4689316   165 FASASGDCTLRIWDVREPGSTMIIPAHDFEILSCDWNkYDDCILATSSVDKTVKVWDVRSYRV 227
Cdd:PTZ00421 141 LASAGADMVVNVWDVERGKAVEVIKCHSDQITSLEWN-LDGSLLCTTSKDKKLNIIDPRDGTI 202
PTZ00420 PTZ00420
coronin; Provisional
 179-265 2.63e-06

coronin; Provisional


Pssm-ID: 240412 [Multi-domain]  Cd Length: 568  Bit Score: 48.79  E-value: 2.63e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4689316   179 VREPgSTMIIPAHDFEILSCDWNKYDDCILATSSVDKTVKVWDVR-------SYRVPLAVLNGHGYAVRKVKFSPHRRSL 251
Cdd:PTZ00420  62 MRKP-PVIKLKGHTSSILDLQFNPCFSEILASGSEDLTIRVWEIPhndesvkEIKDPQCILKGHKKKISIIDWNPMNYYI 140

                         90
                 ....*....|....
gi 4689316   252 IASCSYDMSVCLWD 265
Cdd:PTZ00420 141 MCSSGFDSFVNIWD 154
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 228-265 8.21e-06

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 42.30  E-value: 8.21e-06
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 4689316     228 PLAVLNGHGYAVRKVKFSPHRRsLIASCSYDMSVCLWD 265
Cdd:smart00320   4 LLKTLKGHTGPVTSVAFSPDGK-YLASGSDDGTIKLWD 40
PTZ00421 PTZ00421
coronin; Provisional
 180-317 1.07e-05

coronin; Provisional


Pssm-ID: 173611 [Multi-domain]  Cd Length: 493  Bit Score: 46.81  E-value: 1.07e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4689316   180 REPGSTMIIPAHDFEILSCDWNKYDDCILATSSVDKTVKVWDV------RSYRVPLAVLNGHGYAVRKVKFSPHRRSLIA 253
Cdd:PTZ00421  63 KLASNPPILLGQEGPIIDVAFNPFDPQKLFTASEDGTIMGWGIpeegltQNISDPIVHLQGHTKKVGIVSFHPSAMNVLA 142

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 4689316   254 SCSYDMSVCLWDymVEDALVGR-YDHHTEFAVGIDMSvLVEGLMASTGWDELVYVwqqgMDPRAS 317
Cdd:PTZ00421 143 SAGADMVVNVWD--VERGKAVEvIKCHSDQITSLEWN-LDGSLLCTTSKDKKLNI----IDPRDG 200
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 142-178 2.28e-05

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 40.76  E-value: 2.28e-05
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 4689316     142 VRTFKEHAYCVYQAVWNPkHGDVFASASGDCTLRIWD 178
Cdd:smart00320   5 LKTLKGHTGPVTSVAFSP-DGKYLASGSDDGTIKLWD 40
WD40 pfam00400
WD domain, G-beta repeat;
228-265 3.08e-05

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 40.41  E-value: 3.08e-05
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 4689316    228 PLAVLNGHGYAVRKVKFSPHRRsLIASCSYDMSVCLWD 265
Cdd:pfam00400   3 LLKTLEGHTGSVTSLAFSPDGK-LLASGSDDGTVKVWD 39
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 186-221 1.73e-04

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 38.45  E-value: 1.73e-04
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 4689316     186 MIIPAHDFEILSCDWNKyDDCILATSSVDKTVKVWD 221
Cdd:smart00320   6 KTLKGHTGPVTSVAFSP-DGKYLASGSDDGTIKLWD 40
WD40 pfam00400
WD domain, G-beta repeat;
142-178 3.32e-04

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 37.71  E-value: 3.32e-04
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 4689316    142 VRTFKEHAYCVYQAVWNPkHGDVFASASGDCTLRIWD 178
Cdd:pfam00400   4 LKTLEGHTGSVTSLAFSP-DGKLLASGSDDGTVKVWD 39
WD40 pfam00400
WD domain, G-beta repeat;
185-221 5.60e-04

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 36.94  E-value: 5.60e-04
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 4689316    185 TMIIPAHDFEILSCDWNKyDDCILATSSVDKTVKVWD 221
Cdd:pfam00400   4 LKTLEGHTGSVTSLAFSP-DGKLLASGSDDGTVKVWD 39
PTZ00420 PTZ00420
coronin; Provisional
 228-316 7.53e-04

coronin; Provisional


Pssm-ID: 240412 [Multi-domain]  Cd Length: 568  Bit Score: 41.09  E-value: 7.53e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4689316   228 PLAVLNGHGYAVRKVKFSPHRRSLIASCSYDMSVCLWDYMVEDALVGRYD--------HHTEFAVgIDMSVLVEGLMAST 299
Cdd:PTZ00420  66 PVIKLKGHTSSILDLQFNPCFSEILASGSEDLTIRVWEIPHNDESVKEIKdpqcilkgHKKKISI-IDWNPMNYYIMCSS 144

                         90
                 ....*....|....*..
gi 4689316   300 GWDELVYVWQQGMDPRA 316
Cdd:PTZ00420 145 GFDSFVNIWDIENEKRA 161
WD40 COG2319
WD40 repeat [General function prediction only];
162-308 1.25e-03

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 40.28  E-value: 1.25e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4689316  162 GDVFASASGDCTLRIWDVREPGSTMIIPAHDFEILSCDWNKYDDcILATSSVDKTVKVWDVRSyRVPLAVLNGHGYAVRK 241
Cdd:COG2319   6 GAALAAASADLALALLAAALGALLLLLLGLAAAVASLAASPDGA-RLAAGAGDLTLLLLDAAA-GALLATLLGHTAAVLS 83

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 4689316  242 VKFSPHRRsLIASCSYDMSVCLWDyMVEDALVGRYDHHTEFAVGIDMSvlVEG-LMASTGWDELVYVW 308
Cdd:COG2319  84 VAFSPDGR-LLASASADGTVRLWD-LATGLLLRTLTGHTGAVRSVAFS--PDGkTLASGSADGTVRLW 147
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 95-134 2.72e-03

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 34.98  E-value: 2.72e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 4689316      95 PSNPIRSFQEHAREVQSVDYNPTRRdSFLTSSWDDTVKLW 134
Cdd:smart00320   1 SGELLKTLKGHTGPVTSVAFSPDGK-YLASGSDDGTIKLW 39
WD40 pfam00400
WD domain, G-beta repeat;
96-134 3.64e-03

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 34.63  E-value: 3.64e-03
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 4689316     96 SNPIRSFQEHAREVQSVDYNPTRRdSFLTSSWDDTVKLW 134
Cdd:pfam00400   1 GKLLKTLEGHTGSVTSLAFSPDGK-LLASGSDDGTVKVW 38
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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