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Conserved domains on  [gi|460401039|ref|XP_004246037|]
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polyphenol oxidase B, chloroplastic-like [Solanum lycopersicum]

Protein Classification

tyrosinase family protein( domain architecture ID 10447092)

tyrosinase family protein similar to chloroplastic polyphenol oxidase, chloroplastic (+)-larreatricin hydroxylase, and aureusidin synthase

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Tyrosinase pfam00264
Common central domain of tyrosinase; This family also contains polyphenol oxidases and some ...
 173-386 3.01e-36

Common central domain of tyrosinase; This family also contains polyphenol oxidases and some hemocyanins. Binds two copper ions via two sets of three histidines. This family is related to pfam00372.


:

Pssm-ID: 425566  Cd Length: 209  Bit Score: 134.52  E-value: 3.01e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 460401039  173 PLGFKQQANIHcAYCNGAYNIggkelqvHNSWLFFPFHRWYLYFYERILGKLIDH--PTFALPYWNWD---NPKGMRLPP 247
Cdd:pfam00264   1 PSSYDDFAAIH-GIPFTPWPI-------HGNGLFLPWHRYYLLLFEQALREECGYadPTGTLPYWDWTddpTSPGISSPT 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 460401039  248 MFDREGTSLYDERRNPQVRNG-----TVMDLGTFGDTV------DTTQLLLQTNNLILMYHQMVSNAPCPLLFFG-GRYV 315
Cdd:pfam00264  73 SLGGNGTFIPPNGGVGEVTNGpfanyTVPNLGPHTIRRppdnalAYNPRCLTRDNPLLKQQLNTLDVVDDLLTYQpDYTS 152

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 460401039  316 LGTNIEAPGTIEKI-PHIPVHIWTGtvrdvnapkgkpkygEDMGNFYSAGLDPVFYCHHGNVDRMWNEWKTL 386
Cdd:pfam00264 153 FSNTLEGDGGNEEGlPHNGVHVWVG---------------GDMGDVFTAPNDPIFFLHHANIDRLWAIWQRL 209
PPO1_KFDV pfam12143
Protein of unknown function (DUF_B2219); This domain family is found in eukaryotes, and is ...
 464-596 2.39e-35

Protein of unknown function (DUF_B2219); This domain family is found in eukaryotes, and is typically between 138 and 152 amino acids in length. and the family is found in association with pfam00264. Many members are plant or plastid polyphenol oxidases, and there is a highly conserved sequence motif: KFDV, from which the name derives. This is the C-terminal domain of these oxidases.


:

Pssm-ID: 371919  Cd Length: 130  Bit Score: 129.32  E-value: 2.39e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 460401039  464 FPIfKLDVNTSFSLDRPASLRTQVEKDNKEEILTFSYIKYDSREYIRFDVYLNADKNVKPEDLNQTEYAESYTSLPhtHK 543
Cdd:pfam12143   1 FPL-TLDKTVSVEVKRPKKSRSRKEKEEEEEVLVIEGIEFDDNVYVKFDVFVNVPEDEVAVGPDKTEFAGSFVNVP--HS 77

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 460401039  544 PGDDDYVSTATLQLAITELLKENGLEKEDKIVVTLVPRKGGEGLAIGCVEIAL 596
Cdd:pfam12143  78 VHKHKKKMKTSLRLGITDLLEDLGAEDDDSVVVTLVPRYGGDSVTIGGVSIEL 130
PPO1_DWL pfam12142
Polyphenol oxidase middle domain; This domain family is found in bacteria and eukaryotes, and ...
 394-443 2.10e-19

Polyphenol oxidase middle domain; This domain family is found in bacteria and eukaryotes, and is approximately 50 amino acids in length, and the family is found in association with pfam00264. Most members are annotated as being polyphenol oxidases, and many are from plants or plastids. There is a conserved DWL sequence motif which gives the family its name.


:

Pssm-ID: 463470  Cd Length: 52  Bit Score: 81.93  E-value: 2.10e-19
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 460401039  394 VTEPDLMNSEFFFYDENKKPYLVKVGDCLDTKKMGYDYVKSPTPWRDFKP 443
Cdd:pfam12142   2 FTDPDWLNTSFLFYDENARLVRVKVRDVLDTEKLGYKYQDVPLPWLNARP 51
 
Name Accession Description Interval E-value
Tyrosinase pfam00264
Common central domain of tyrosinase; This family also contains polyphenol oxidases and some ...
 173-386 3.01e-36

Common central domain of tyrosinase; This family also contains polyphenol oxidases and some hemocyanins. Binds two copper ions via two sets of three histidines. This family is related to pfam00372.


Pssm-ID: 425566  Cd Length: 209  Bit Score: 134.52  E-value: 3.01e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 460401039  173 PLGFKQQANIHcAYCNGAYNIggkelqvHNSWLFFPFHRWYLYFYERILGKLIDH--PTFALPYWNWD---NPKGMRLPP 247
Cdd:pfam00264   1 PSSYDDFAAIH-GIPFTPWPI-------HGNGLFLPWHRYYLLLFEQALREECGYadPTGTLPYWDWTddpTSPGISSPT 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 460401039  248 MFDREGTSLYDERRNPQVRNG-----TVMDLGTFGDTV------DTTQLLLQTNNLILMYHQMVSNAPCPLLFFG-GRYV 315
Cdd:pfam00264  73 SLGGNGTFIPPNGGVGEVTNGpfanyTVPNLGPHTIRRppdnalAYNPRCLTRDNPLLKQQLNTLDVVDDLLTYQpDYTS 152

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 460401039  316 LGTNIEAPGTIEKI-PHIPVHIWTGtvrdvnapkgkpkygEDMGNFYSAGLDPVFYCHHGNVDRMWNEWKTL 386
Cdd:pfam00264 153 FSNTLEGDGGNEEGlPHNGVHVWVG---------------GDMGDVFTAPNDPIFFLHHANIDRLWAIWQRL 209
PPO1_KFDV pfam12143
Protein of unknown function (DUF_B2219); This domain family is found in eukaryotes, and is ...
 464-596 2.39e-35

Protein of unknown function (DUF_B2219); This domain family is found in eukaryotes, and is typically between 138 and 152 amino acids in length. and the family is found in association with pfam00264. Many members are plant or plastid polyphenol oxidases, and there is a highly conserved sequence motif: KFDV, from which the name derives. This is the C-terminal domain of these oxidases.


Pssm-ID: 371919  Cd Length: 130  Bit Score: 129.32  E-value: 2.39e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 460401039  464 FPIfKLDVNTSFSLDRPASLRTQVEKDNKEEILTFSYIKYDSREYIRFDVYLNADKNVKPEDLNQTEYAESYTSLPhtHK 543
Cdd:pfam12143   1 FPL-TLDKTVSVEVKRPKKSRSRKEKEEEEEVLVIEGIEFDDNVYVKFDVFVNVPEDEVAVGPDKTEFAGSFVNVP--HS 77

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 460401039  544 PGDDDYVSTATLQLAITELLKENGLEKEDKIVVTLVPRKGGEGLAIGCVEIAL 596
Cdd:pfam12143  78 VHKHKKKMKTSLRLGITDLLEDLGAEDDDSVVVTLVPRYGGDSVTIGGVSIEL 130
PPO1_DWL pfam12142
Polyphenol oxidase middle domain; This domain family is found in bacteria and eukaryotes, and ...
 394-443 2.10e-19

Polyphenol oxidase middle domain; This domain family is found in bacteria and eukaryotes, and is approximately 50 amino acids in length, and the family is found in association with pfam00264. Most members are annotated as being polyphenol oxidases, and many are from plants or plastids. There is a conserved DWL sequence motif which gives the family its name.


Pssm-ID: 463470  Cd Length: 52  Bit Score: 81.93  E-value: 2.10e-19
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 460401039  394 VTEPDLMNSEFFFYDENKKPYLVKVGDCLDTKKMGYDYVKSPTPWRDFKP 443
Cdd:pfam12142   2 FTDPDWLNTSFLFYDENARLVRVKVRDVLDTEKLGYKYQDVPLPWLNARP 51
 
Name Accession Description Interval E-value
Tyrosinase pfam00264
Common central domain of tyrosinase; This family also contains polyphenol oxidases and some ...
 173-386 3.01e-36

Common central domain of tyrosinase; This family also contains polyphenol oxidases and some hemocyanins. Binds two copper ions via two sets of three histidines. This family is related to pfam00372.


Pssm-ID: 425566  Cd Length: 209  Bit Score: 134.52  E-value: 3.01e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 460401039  173 PLGFKQQANIHcAYCNGAYNIggkelqvHNSWLFFPFHRWYLYFYERILGKLIDH--PTFALPYWNWD---NPKGMRLPP 247
Cdd:pfam00264   1 PSSYDDFAAIH-GIPFTPWPI-------HGNGLFLPWHRYYLLLFEQALREECGYadPTGTLPYWDWTddpTSPGISSPT 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 460401039  248 MFDREGTSLYDERRNPQVRNG-----TVMDLGTFGDTV------DTTQLLLQTNNLILMYHQMVSNAPCPLLFFG-GRYV 315
Cdd:pfam00264  73 SLGGNGTFIPPNGGVGEVTNGpfanyTVPNLGPHTIRRppdnalAYNPRCLTRDNPLLKQQLNTLDVVDDLLTYQpDYTS 152

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 460401039  316 LGTNIEAPGTIEKI-PHIPVHIWTGtvrdvnapkgkpkygEDMGNFYSAGLDPVFYCHHGNVDRMWNEWKTL 386
Cdd:pfam00264 153 FSNTLEGDGGNEEGlPHNGVHVWVG---------------GDMGDVFTAPNDPIFFLHHANIDRLWAIWQRL 209
PPO1_KFDV pfam12143
Protein of unknown function (DUF_B2219); This domain family is found in eukaryotes, and is ...
 464-596 2.39e-35

Protein of unknown function (DUF_B2219); This domain family is found in eukaryotes, and is typically between 138 and 152 amino acids in length. and the family is found in association with pfam00264. Many members are plant or plastid polyphenol oxidases, and there is a highly conserved sequence motif: KFDV, from which the name derives. This is the C-terminal domain of these oxidases.


Pssm-ID: 371919  Cd Length: 130  Bit Score: 129.32  E-value: 2.39e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 460401039  464 FPIfKLDVNTSFSLDRPASLRTQVEKDNKEEILTFSYIKYDSREYIRFDVYLNADKNVKPEDLNQTEYAESYTSLPhtHK 543
Cdd:pfam12143   1 FPL-TLDKTVSVEVKRPKKSRSRKEKEEEEEVLVIEGIEFDDNVYVKFDVFVNVPEDEVAVGPDKTEFAGSFVNVP--HS 77

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 460401039  544 PGDDDYVSTATLQLAITELLKENGLEKEDKIVVTLVPRKGGEGLAIGCVEIAL 596
Cdd:pfam12143  78 VHKHKKKMKTSLRLGITDLLEDLGAEDDDSVVVTLVPRYGGDSVTIGGVSIEL 130
PPO1_DWL pfam12142
Polyphenol oxidase middle domain; This domain family is found in bacteria and eukaryotes, and ...
 394-443 2.10e-19

Polyphenol oxidase middle domain; This domain family is found in bacteria and eukaryotes, and is approximately 50 amino acids in length, and the family is found in association with pfam00264. Most members are annotated as being polyphenol oxidases, and many are from plants or plastids. There is a conserved DWL sequence motif which gives the family its name.


Pssm-ID: 463470  Cd Length: 52  Bit Score: 81.93  E-value: 2.10e-19
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 460401039  394 VTEPDLMNSEFFFYDENKKPYLVKVGDCLDTKKMGYDYVKSPTPWRDFKP 443
Cdd:pfam12142   2 FTDPDWLNTSFLFYDENARLVRVKVRDVLDTEKLGYKYQDVPLPWLNARP 51
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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