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Conserved domains on  [gi|4557567|ref|NP_001423|]
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proepiregulin preproprotein [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA03099 super family cl31525
epidermal growth factor-like protein (EGF-like protein); Provisional
 64-148 3.75e-11

epidermal growth factor-like protein (EGF-like protein); Provisional


The actual alignment was detected with superfamily member PHA03099:

Pssm-ID: 165381  Cd Length: 139  Bit Score: 57.73  E-value: 3.75e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4557567    64 SITKCSSDMNGYCLHGQCIYLVDMSQNYCRCEVGYTGVRCEHFFLTVHQPLSK-----EYVALTVILIILFLITVVGSTY 138
Cdd:PHA03099  41 AIRLCGPEGDGYCLHGDCIHARDIDGMYCRCSHGYTGIRCQHVVLVDYQRSEKpntttSYIPSPGIVLVLVGIIITCCLL 120

                         90
                 ....*....|
gi 4557567   139 YFCRWYRNRK 148
Cdd:PHA03099 121 SVYRFTRRTK 130
 
Name Accession Description Interval E-value
PHA03099 PHA03099
epidermal growth factor-like protein (EGF-like protein); Provisional
 64-148 3.75e-11

epidermal growth factor-like protein (EGF-like protein); Provisional


Pssm-ID: 165381  Cd Length: 139  Bit Score: 57.73  E-value: 3.75e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4557567    64 SITKCSSDMNGYCLHGQCIYLVDMSQNYCRCEVGYTGVRCEHFFLTVHQPLSK-----EYVALTVILIILFLITVVGSTY 138
Cdd:PHA03099  41 AIRLCGPEGDGYCLHGDCIHARDIDGMYCRCSHGYTGIRCQHVVLVDYQRSEKpntttSYIPSPGIVLVLVGIIITCCLL 120

                         90
                 ....*....|
gi 4557567   139 YFCRWYRNRK 148
Cdd:PHA03099 121 SVYRFTRRTK 130
 
Name Accession Description Interval E-value
PHA03099 PHA03099
epidermal growth factor-like protein (EGF-like protein); Provisional
 64-148 3.75e-11

epidermal growth factor-like protein (EGF-like protein); Provisional


Pssm-ID: 165381  Cd Length: 139  Bit Score: 57.73  E-value: 3.75e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4557567    64 SITKCSSDMNGYCLHGQCIYLVDMSQNYCRCEVGYTGVRCEHFFLTVHQPLSK-----EYVALTVILIILFLITVVGSTY 138
Cdd:PHA03099  41 AIRLCGPEGDGYCLHGDCIHARDIDGMYCRCSHGYTGIRCQHVVLVDYQRSEKpntttSYIPSPGIVLVLVGIIITCCLL 120

                         90
                 ....*....|
gi 4557567   139 YFCRWYRNRK 148
Cdd:PHA03099 121 SVYRFTRRTK 130
PHA02887 PHA02887
EGF-like protein; Provisional
 67-104 3.44e-10

EGF-like protein; Provisional


Pssm-ID: 165214  Cd Length: 126  Bit Score: 54.93  E-value: 3.44e-10
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 4557567    67 KCSSDMNGYCLHGQCIYLVDMSQNYCRCEVGYTGVRCE 104
Cdd:PHA02887  85 KCKNDFNDFCINGECMNIIDLDEKFCICNKGYTGIRCD 122
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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