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myb-related protein B isoform 1 [Homo sapiens]
SANT and Cmyb_C domain-containing protein( domain architecture ID 13851054)
SANT and Cmyb_C domain-containing protein
List of domain hits
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Name | Accession | Description | Interval | E-value | |||
Cmyb_C | pfam09316 | C-myb, C-terminal; Members of this family are predominantly found in the proto-oncogene c-myb ... |
451-594 | 4.12e-56 | |||
C-myb, C-terminal; Members of this family are predominantly found in the proto-oncogene c-myb and the viral transforming protein myb. Truncation of the domain results in 'activation' of c-myb and subsequent tumourigenesis. : Pssm-ID: 462753 Cd Length: 157 Bit Score: 188.34 E-value: 4.12e-56
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PLN03091 super family | cl33633 | hypothetical protein; Provisional |
81-197 | 3.51e-29 | |||
hypothetical protein; Provisional The actual alignment was detected with superfamily member PLN03091: Pssm-ID: 215570 [Multi-domain] Cd Length: 459 Bit Score: 121.62 E-value: 3.51e-29
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Myb_DNA-bind_6 | pfam13921 | Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ... |
34-94 | 2.00e-19 | |||
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family. : Pssm-ID: 372817 [Multi-domain] Cd Length: 60 Bit Score: 82.36 E-value: 2.00e-19
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Name | Accession | Description | Interval | E-value | |||
Cmyb_C | pfam09316 | C-myb, C-terminal; Members of this family are predominantly found in the proto-oncogene c-myb ... |
451-594 | 4.12e-56 | |||
C-myb, C-terminal; Members of this family are predominantly found in the proto-oncogene c-myb and the viral transforming protein myb. Truncation of the domain results in 'activation' of c-myb and subsequent tumourigenesis. Pssm-ID: 462753 Cd Length: 157 Bit Score: 188.34 E-value: 4.12e-56
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PLN03091 | PLN03091 | hypothetical protein; Provisional |
81-197 | 3.51e-29 | |||
hypothetical protein; Provisional Pssm-ID: 215570 [Multi-domain] Cd Length: 459 Bit Score: 121.62 E-value: 3.51e-29
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REB1 | COG5147 | Myb superfamily proteins, including transcription factors and mRNA splicing factors ... |
80-195 | 1.29e-27 | |||
Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning]; Pssm-ID: 227476 [Multi-domain] Cd Length: 512 Bit Score: 117.58 E-value: 1.29e-27
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Myb_DNA-bind_6 | pfam13921 | Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ... |
34-94 | 2.00e-19 | |||
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family. Pssm-ID: 372817 [Multi-domain] Cd Length: 60 Bit Score: 82.36 E-value: 2.00e-19
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Myb_DNA-bind_6 | pfam13921 | Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ... |
86-144 | 2.72e-18 | |||
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family. Pssm-ID: 372817 [Multi-domain] Cd Length: 60 Bit Score: 79.28 E-value: 2.72e-18
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SANT | smart00717 | SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; |
83-131 | 3.70e-17 | |||
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; Pssm-ID: 197842 [Multi-domain] Cd Length: 49 Bit Score: 75.34 E-value: 3.70e-17
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SANT | cd00167 | 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ... |
85-129 | 1.11e-16 | |||
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA. Pssm-ID: 238096 [Multi-domain] Cd Length: 45 Bit Score: 74.15 E-value: 1.11e-16
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SANT | smart00717 | SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; |
31-79 | 3.88e-14 | |||
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; Pssm-ID: 197842 [Multi-domain] Cd Length: 49 Bit Score: 66.86 E-value: 3.88e-14
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SANT | cd00167 | 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ... |
33-77 | 1.43e-13 | |||
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA. Pssm-ID: 238096 [Multi-domain] Cd Length: 45 Bit Score: 65.29 E-value: 1.43e-13
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Name | Accession | Description | Interval | E-value | ||||
Cmyb_C | pfam09316 | C-myb, C-terminal; Members of this family are predominantly found in the proto-oncogene c-myb ... |
451-594 | 4.12e-56 | ||||
C-myb, C-terminal; Members of this family are predominantly found in the proto-oncogene c-myb and the viral transforming protein myb. Truncation of the domain results in 'activation' of c-myb and subsequent tumourigenesis. Pssm-ID: 462753 Cd Length: 157 Bit Score: 188.34 E-value: 4.12e-56
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PLN03091 | PLN03091 | hypothetical protein; Provisional |
81-197 | 3.51e-29 | ||||
hypothetical protein; Provisional Pssm-ID: 215570 [Multi-domain] Cd Length: 459 Bit Score: 121.62 E-value: 3.51e-29
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REB1 | COG5147 | Myb superfamily proteins, including transcription factors and mRNA splicing factors ... |
80-195 | 1.29e-27 | ||||
Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning]; Pssm-ID: 227476 [Multi-domain] Cd Length: 512 Bit Score: 117.58 E-value: 1.29e-27
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PLN03212 | PLN03212 | Transcription repressor MYB5; Provisional |
83-184 | 6.39e-26 | ||||
Transcription repressor MYB5; Provisional Pssm-ID: 178751 [Multi-domain] Cd Length: 249 Bit Score: 107.09 E-value: 6.39e-26
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Myb_DNA-bind_6 | pfam13921 | Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ... |
34-94 | 2.00e-19 | ||||
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family. Pssm-ID: 372817 [Multi-domain] Cd Length: 60 Bit Score: 82.36 E-value: 2.00e-19
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Myb_DNA-bind_6 | pfam13921 | Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ... |
86-144 | 2.72e-18 | ||||
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family. Pssm-ID: 372817 [Multi-domain] Cd Length: 60 Bit Score: 79.28 E-value: 2.72e-18
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SANT | smart00717 | SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; |
83-131 | 3.70e-17 | ||||
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; Pssm-ID: 197842 [Multi-domain] Cd Length: 49 Bit Score: 75.34 E-value: 3.70e-17
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Myb_DNA-binding | pfam00249 | Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ... |
83-129 | 8.26e-17 | ||||
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family. Pssm-ID: 459731 [Multi-domain] Cd Length: 46 Bit Score: 74.46 E-value: 8.26e-17
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SANT | cd00167 | 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ... |
85-129 | 1.11e-16 | ||||
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA. Pssm-ID: 238096 [Multi-domain] Cd Length: 45 Bit Score: 74.15 E-value: 1.11e-16
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Myb_DNA-binding | pfam00249 | Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ... |
135-178 | 9.37e-16 | ||||
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family. Pssm-ID: 459731 [Multi-domain] Cd Length: 46 Bit Score: 71.38 E-value: 9.37e-16
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SANT | smart00717 | SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; |
31-79 | 3.88e-14 | ||||
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; Pssm-ID: 197842 [Multi-domain] Cd Length: 49 Bit Score: 66.86 E-value: 3.88e-14
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SANT | cd00167 | 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ... |
33-77 | 1.43e-13 | ||||
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA. Pssm-ID: 238096 [Multi-domain] Cd Length: 45 Bit Score: 65.29 E-value: 1.43e-13
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SANT | cd00167 | 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ... |
138-177 | 9.62e-13 | ||||
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA. Pssm-ID: 238096 [Multi-domain] Cd Length: 45 Bit Score: 62.98 E-value: 9.62e-13
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SANT | smart00717 | SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; |
135-182 | 1.36e-12 | ||||
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; Pssm-ID: 197842 [Multi-domain] Cd Length: 49 Bit Score: 62.63 E-value: 1.36e-12
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Myb_DNA-binding | pfam00249 | Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ... |
31-77 | 2.05e-12 | ||||
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family. Pssm-ID: 459731 [Multi-domain] Cd Length: 46 Bit Score: 61.75 E-value: 2.05e-12
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Myb_DNA-bind_6 | pfam13921 | Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ... |
138-189 | 4.59e-09 | ||||
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family. Pssm-ID: 372817 [Multi-domain] Cd Length: 60 Bit Score: 53.08 E-value: 4.59e-09
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SANT_CDC5_II | cd11659 | SANT/myb-like DNA-binding domain of Cell Division Cycle 5-Like Protein repeat II; In humans, ... |
79-125 | 5.74e-08 | ||||
SANT/myb-like DNA-binding domain of Cell Division Cycle 5-Like Protein repeat II; In humans, cell division cycle 5-like protein (CDC5) functions in pre-mRNA splicing in cell cycle control. The DNA-binding, myb-like domain of CDC5 is a member of the SANT/myb group. SANT is named after 'SWI3, ADA2, N-CoR and TFIIIB', several factors that share this domain. The SANT domain resembles the 3 alpha-helix bundle of DNA-binding Myb domains and is found in a diverse set of proteins. Pssm-ID: 212557 [Multi-domain] Cd Length: 53 Bit Score: 49.62 E-value: 5.74e-08
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SANT_TRF | cd11660 | Telomere repeat binding factor-like DNA-binding domains of the SANT/myb-like family; Human ... |
85-127 | 3.90e-07 | ||||
Telomere repeat binding factor-like DNA-binding domains of the SANT/myb-like family; Human telomere repeat binding factors, TRF1 and TRF2, function as part of the 6 component shelterin complex. TRF2 binds DNA and recruits RAP1 (via binding to the RAP1 protein c-terminal (RCT)) and TIN2 in the protection of telomeres from DNA repair machinery. Metazoan shelterin consists of 3 DNA binding proteins (TRF2, TRF1, and POT1) and 3 recruited proteins that bind to one or more of these DNA-binding proteins (RAP1, TIN2, TPP1). Schizosaccharomyces pombe TAZ1 is an orthlog and binds RAP1. Human TRF1 and TRF2 bind double-stranded DNA. hTRF2 consists of a basic N-terminus, a TRF homology domain, the RAP1 binding motif (RBM), the TIN2 binding motif (TBM) and a myb-like DNA binding domain, SANT, named after 'SWI3, ADA2, N-CoR and TFIIIB', several factors that share this domain. Tandem copies of the domain bind telomeric DNA tandem repeats as part of the capping complex. The single myb-like domain of TRF-type proteins is similar to the tandem myb_like domains found in yeast RAP1. Pssm-ID: 212558 [Multi-domain] Cd Length: 50 Bit Score: 47.18 E-value: 3.90e-07
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SANT_TRF | cd11660 | Telomere repeat binding factor-like DNA-binding domains of the SANT/myb-like family; Human ... |
32-79 | 4.30e-05 | ||||
Telomere repeat binding factor-like DNA-binding domains of the SANT/myb-like family; Human telomere repeat binding factors, TRF1 and TRF2, function as part of the 6 component shelterin complex. TRF2 binds DNA and recruits RAP1 (via binding to the RAP1 protein c-terminal (RCT)) and TIN2 in the protection of telomeres from DNA repair machinery. Metazoan shelterin consists of 3 DNA binding proteins (TRF2, TRF1, and POT1) and 3 recruited proteins that bind to one or more of these DNA-binding proteins (RAP1, TIN2, TPP1). Schizosaccharomyces pombe TAZ1 is an orthlog and binds RAP1. Human TRF1 and TRF2 bind double-stranded DNA. hTRF2 consists of a basic N-terminus, a TRF homology domain, the RAP1 binding motif (RBM), the TIN2 binding motif (TBM) and a myb-like DNA binding domain, SANT, named after 'SWI3, ADA2, N-CoR and TFIIIB', several factors that share this domain. Tandem copies of the domain bind telomeric DNA tandem repeats as part of the capping complex. The single myb-like domain of TRF-type proteins is similar to the tandem myb_like domains found in yeast RAP1. Pssm-ID: 212558 [Multi-domain] Cd Length: 50 Bit Score: 41.40 E-value: 4.30e-05
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SANT_CDC5_II | cd11659 | SANT/myb-like DNA-binding domain of Cell Division Cycle 5-Like Protein repeat II; In humans, ... |
131-170 | 1.01e-04 | ||||
SANT/myb-like DNA-binding domain of Cell Division Cycle 5-Like Protein repeat II; In humans, cell division cycle 5-like protein (CDC5) functions in pre-mRNA splicing in cell cycle control. The DNA-binding, myb-like domain of CDC5 is a member of the SANT/myb group. SANT is named after 'SWI3, ADA2, N-CoR and TFIIIB', several factors that share this domain. The SANT domain resembles the 3 alpha-helix bundle of DNA-binding Myb domains and is found in a diverse set of proteins. Pssm-ID: 212557 [Multi-domain] Cd Length: 53 Bit Score: 40.37 E-value: 1.01e-04
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REB1 | COG5147 | Myb superfamily proteins, including transcription factors and mRNA splicing factors ... |
24-181 | 1.43e-04 | ||||
Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning]; Pssm-ID: 227476 [Multi-domain] Cd Length: 512 Bit Score: 45.16 E-value: 1.43e-04
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GT1 | cd12203 | GT1, myb-like, SANT family; GT-1, a myb-like protein, is one of the GT trihelix transcription ... |
86-136 | 6.34e-03 | ||||
GT1, myb-like, SANT family; GT-1, a myb-like protein, is one of the GT trihelix transcription factors. GT-1 binds the GT cis-element of rbcS-3A, a light-induced gene, as a dimer. Arabidopsis GT-1 is a trans-activator and acts in the stabilization of components of the transcription pre-initiation complex comprised of TFIIA-TBP-TATA. The isolated GT-1 DNA-binding domain is sufficient to bind DNA. This region closely resembles the myb domain, but with longer helices. It has been proposed that GT-1 may respond to light signals via calcium-dependent phosphorylation to create a light-modulated molecular switch. These proteins are members of the SANT/myb group. SANT is named after 'SWI3, ADA2, N-CoR and TFIIIB', several factors that share this domain. The SANT domain resembles the 3 alpha-helix bundle of the DNA-binding Myb domains and is found in a diverse set of proteins. Pssm-ID: 213402 Cd Length: 66 Bit Score: 35.72 E-value: 6.34e-03
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Blast search parameters | ||||
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