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Conserved domains on  [gi|447213450|ref|WP_001290706|]
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MULTISPECIES: assimilatory sulfite reductase (NADPH) hemoprotein subunit [Enterobacteriaceae]

Protein Classification

assimilatory sulfite reductase (NADPH) hemoprotein subunit( domain architecture ID 11486660)

assimilatory sulfite reductase (NADPH) hemoprotein subunit is a component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide

EC:  1.8.1.2
Gene Ontology:  GO:0016491|GO:0051539|GO:0050661|GO:0004783|GO:0009337
PubMed:  23153334|7569952|29852252

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
PRK13504 PRK13504
NADPH-dependent assimilatory sulfite reductase hemoprotein subunit;
5-569 0e+00

NADPH-dependent assimilatory sulfite reductase hemoprotein subunit;


:

Pssm-ID: 237402 [Multi-domain]  Cd Length: 569  Bit Score: 1132.98  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450   5 HPGPLVVEGKLTDAERMKLESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAMLLRC 84
Cdd:PRK13504   1 HPGPLAVEGKLSDVERIKLESNYLRGTIAEELNDGLTGGFSEDDFQLLKFHGSYQQDDRDIRAERAEQKLEPAYQFMLRC 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450  85 RLPGGVITTKQWQAIDKFAGENTiYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYES 164
Cdd:PRK13504  81 RLPGGVITPQQWLALDKLADEYG-NGTLRLTTRQTFQFHGILKKNLKPVIQTINSVLLDTLAACGDVNRNVMCTPNPYES 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450 165 QLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVAT---TDEEPILGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIA 241
Cdd:PRK13504 160 RLHAEAYEWAKKISDHLLPRTRAYAEIWLDGEKVATfsgTEEEPIYGKTYLPRKFKIAVAVPPDNDVDVYANDLGFVAIA 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450 242 ENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVETFKA 321
Cdd:PRK13504 240 ENGKLVGFNVLVGGGMGMTHGDKETYPRLADELGYVPPEDVLDVAEAVVTTQRDYGNRTDRKNARLKYTLERVGLDWFKA 319

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450 322 EVERRAGIKFEPIRPYEFTGRGDRIGWVKGIDDNWHLTLFIENGRILDYPGRPLKTGLLEIAKIHKGDFRITANQNLIIA 401
Cdd:PRK13504 320 EVERRAGKKLEPARPYEFTGRGDRLGWVEGIDGKWHLTLFIENGRIKDYPGRPLKTGLREIAKIHKGDFRLTANQNLIIA 399

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450 402 GVPESEKAKIEKIAKESGLMNAV--TPQRENSMACVSFPTCPLAMAEAERFLPSFIDNIDNLMAKHGVSDEHIVMRVTGC 479
Cdd:PRK13504 400 NVPPSDKAKIEALLREYGLIDGVeeSPLRRNSMACVALPTCGLAMAEAERYLPSFIDRIEALLAKHGLSDEHIVIRMTGC 479

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450 480 PNGCGRAMLAEVGLVGKAPGRYNLHLGGNRIGTRIPRMYKENITEPEILASLDELIGRWAKEREAGEGFGDFTVRAGIIR 559
Cdd:PRK13504 480 PNGCARPYLAEIGLVGKAPGRYNLYLGGSFNGTRLPKMYRENITEEEILATLDPLLGRWAKEREPGEGFGDFVIRAGIIR 559

                        570
                 ....*....|
gi 447213450 560 PVLDPARDLW 569
Cdd:PRK13504 560 EVLDGARDFH 569
 
Name Accession Description Interval E-value
PRK13504 PRK13504
NADPH-dependent assimilatory sulfite reductase hemoprotein subunit;
5-569 0e+00

NADPH-dependent assimilatory sulfite reductase hemoprotein subunit;


Pssm-ID: 237402 [Multi-domain]  Cd Length: 569  Bit Score: 1132.98  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450   5 HPGPLVVEGKLTDAERMKLESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAMLLRC 84
Cdd:PRK13504   1 HPGPLAVEGKLSDVERIKLESNYLRGTIAEELNDGLTGGFSEDDFQLLKFHGSYQQDDRDIRAERAEQKLEPAYQFMLRC 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450  85 RLPGGVITTKQWQAIDKFAGENTiYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYES 164
Cdd:PRK13504  81 RLPGGVITPQQWLALDKLADEYG-NGTLRLTTRQTFQFHGILKKNLKPVIQTINSVLLDTLAACGDVNRNVMCTPNPYES 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450 165 QLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVAT---TDEEPILGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIA 241
Cdd:PRK13504 160 RLHAEAYEWAKKISDHLLPRTRAYAEIWLDGEKVATfsgTEEEPIYGKTYLPRKFKIAVAVPPDNDVDVYANDLGFVAIA 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450 242 ENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVETFKA 321
Cdd:PRK13504 240 ENGKLVGFNVLVGGGMGMTHGDKETYPRLADELGYVPPEDVLDVAEAVVTTQRDYGNRTDRKNARLKYTLERVGLDWFKA 319

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450 322 EVERRAGIKFEPIRPYEFTGRGDRIGWVKGIDDNWHLTLFIENGRILDYPGRPLKTGLLEIAKIHKGDFRITANQNLIIA 401
Cdd:PRK13504 320 EVERRAGKKLEPARPYEFTGRGDRLGWVEGIDGKWHLTLFIENGRIKDYPGRPLKTGLREIAKIHKGDFRLTANQNLIIA 399

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450 402 GVPESEKAKIEKIAKESGLMNAV--TPQRENSMACVSFPTCPLAMAEAERFLPSFIDNIDNLMAKHGVSDEHIVMRVTGC 479
Cdd:PRK13504 400 NVPPSDKAKIEALLREYGLIDGVeeSPLRRNSMACVALPTCGLAMAEAERYLPSFIDRIEALLAKHGLSDEHIVIRMTGC 479

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450 480 PNGCGRAMLAEVGLVGKAPGRYNLHLGGNRIGTRIPRMYKENITEPEILASLDELIGRWAKEREAGEGFGDFTVRAGIIR 559
Cdd:PRK13504 480 PNGCARPYLAEIGLVGKAPGRYNLYLGGSFNGTRLPKMYRENITEEEILATLDPLLGRWAKEREPGEGFGDFVIRAGIIR 559

                        570
                 ....*....|
gi 447213450 560 PVLDPARDLW 569
Cdd:PRK13504 560 EVLDGARDFH 569
CysI TIGR02041
sulfite reductase (NADPH) hemoprotein, beta-component; Sulfite reductase (NADPH) catalyzes a ...
 19-558 0e+00

sulfite reductase (NADPH) hemoprotein, beta-component; Sulfite reductase (NADPH) catalyzes a six electron reduction of sulfite to sulfide in prokaryotic organisms. It is a complex oligomeric enzyme composed of two different peptides with a subunit composition of alpha(8)-beta(4). The alpha component, encoded by cysJ, is a flavoprotein containing both FMN and FAD, while the beta component, encoded by cysI, is a siroheme, iron-sulfur protein. In Salmonella typhimurium and Escherichia coli, both the alpha and beta subunits of sulfite reductase are located in a unidirectional gene cluster along with phosphoadenosine phosphosulfate reductase, which catalyzes a two step reduction of PAPS to give free sulfite. In cyanobacteria and plant species, sulfite reductase ferredoxin (EC 1.8.7.1) catalyzes the reduction of sulfite to sulfide. [Central intermediary metabolism, Sulfur metabolism]


Pssm-ID: 273941 [Multi-domain]  Cd Length: 541  Bit Score: 1067.43  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450   19 ERMKLESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAMLLRCRLPGGVITTKQWQA 98
Cdd:TIGR02041   1 ERIKEESNYLRGTILEDLADPLTGGFKGDNFQLIRFHGMYQQDDRDLRAERAEQKLEPRYAMMLRCRLPGGVITPKQWLA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450   99 IDKFAGENTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQLHAEAYEWAKKIS 178
Cdd:TIGR02041  81 IDKFAREYTNYGSIRLTNRQTFQFHGILKKNLKPVHQMLHSVGLDSLATAGDVNRNVLCTSNPYESELHAEAYEWAKKIS 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450  179 EHLLPRTRAYAEIWLDQEKVATTDE-EPILGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGL 257
Cdd:TIGR02041 161 EHLLPRTRAYAEIWLDQEKVAGTEEvEPILGPTYLPRKFKTTVVIPPQNDVDVYANDLGFVAIAENGKLVGFNVLIGGGL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450  258 SIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVETFKAEVERRAGIKFEPIRPY 337
Cdd:TIGR02041 241 SMEHGNKKTYPRLASEIGFIPPEHTLAVAEAVVTTQRDFGNRTDRKNARTKYTIERMGLDTFKAEVERRAGIKFEPARPY 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450  338 EFTGRGDRIGWVKGIDDNWHLTLFIENGRILDYPGRPLKTGLLEIAKIHKGDFRITANQNLIIAGVPESEKAKIEKIAKE 417
Cdd:TIGR02041 321 EFTGRGDRIGWVKGIDGNWHLTLFIENGRILDYPDKPLKTGLLEIAKIHKGDFRITANQNLIIAGVPEGGKAKIEKLARQ 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450  418 SGLMNAVTPQRENSMACVSFPTCPLAMAEAERFLPSFIDNIDNLMAKHGVSDEHIVMRVTGCPNGCGRAMLAEVGLVGKA 497
Cdd:TIGR02041 401 YGLINAVTALRENSMACVSFPTCPLAMAEAERYLPDFIDKLDNIMAKHGLSDEEIVLRVTGCPNGCGRAMLAEIGLVGKA 480

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 447213450  498 PGRYNLHLGGNRIGTRIPRMYKENITEPEILASLDELIGRWAKEREAGEGFGDFTVRAGII 558
Cdd:TIGR02041 481 PGRYNLHLGGNRIGTRIPRLYKENITEPEILAELDELIGRWAKERKPGEGFGDFLIRAGII 541
CysI COG0155
Sulfite reductase, beta subunit (hemoprotein) [Inorganic ion transport and metabolism]; ...
 15-566 0e+00

Sulfite reductase, beta subunit (hemoprotein) [Inorganic ion transport and metabolism]; Sulfite reductase, beta subunit (hemoprotein) is part of the Pathway/BioSystem: Cysteine biosynthesis


Pssm-ID: 439925 [Multi-domain]  Cd Length: 519  Bit Score: 581.31  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450  15 LTDAERMKLESNYLR-GTIAEDLNDGLTGGFKGDNF-LLIRFHGMYQQDDrdiraeraeqklePRHAMLLRCRLPGGVIT 92
Cdd:COG0155    1 LYKYERIKREDVRSRlGTFAEQLGRFLTGEISEDDFrLRLKFHGLYQQRD-------------PDGAFMLRVRIPGGVLT 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450  93 TKQWQAIDKFAGENTiYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQL-HAEAY 171
Cdd:COG0155   68 PEQLRALADIAREYG-RGYLHLTTRQNIQLHWILLEDLPEILRELAEVGLTTIGACGDVVRNVTASPLAGVDPDeLFDVR 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450 172 EWAKKISEHLLprtrayaeiwldqekvattdEEPILgqTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNL 251
Cdd:COG0155  147 PYAEAISQHLL--------------------GHPEY--TYLPRKFKIAFSGPPEDDADVEINDLGFIAVVKEDGLVGFNV 204

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450 252 LVGGGLSIEHgnkktyaRTASEFG-YLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVETFKAEVERR-AGI 329
Cdd:COG0155  205 LVGGGLGRTP-------RLADVLGeFVPPEDLLDVAEAVVRVFRDYGDRDNRKKARLKYLVDDLGVEKFREEVEEEyLGF 277

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450 330 KFEPI-RPYEFTGRGDRIGWVKGI-DDNWHLTLFIENGRILDYPgrplKTGLLEIAKIH-KGDFRITANQNLIIAGVPES 406
Cdd:COG0155  278 PLEPApRPLPAFARWDHLGVHEQKqDGLYYVGLSVENGRITDEQ----LRALADLAERYgSGEIRLTPNQNLILADVPEE 353

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450 407 EKAKIEKIAKESGLMNAVTPQRENSMACVSFPTCPLAMAEAERFLPSFIDNIDnlmAKHG--VSDEHIVMRVTGCPNGCG 484
Cdd:COG0155  354 DLPALEAALRALGLATPPSGLRRDSIACPGLPTCKLAIAESKRLAPALADRLE---EDLDglHDDEPIRIRISGCPNSCG 430

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450 485 RAMLAEVGLVGKAP-GR---YNLHLGGNRIG-TRIPRMYKENITEPEILASLDELIGRWAKEREAGEGFGDFTVRAGI-- 557
Cdd:COG0155  431 RHYIADIGLVGKAKkGVveaYQLYLGGGLGGdARLGRKYGPKVPADEIPDALERLLEAYLAEREEGESFGDFVRRVGIep 510


                 ....*....
gi 447213450 558 IRPVLDPAR 566
Cdd:COG0155  511 LKELLYAAA 519
NIR_SIR pfam01077
Nitrite and sulphite reductase 4Fe-4S domain; Sulphite and nitrite reductases are vital in the ...
 173-326 9.97e-48

Nitrite and sulphite reductase 4Fe-4S domain; Sulphite and nitrite reductases are vital in the biosynthetic assimilation of sulphur and nitrogen, respectfully. They are also both important for the dissimilation of oxidized anions for energy transduction.


Pssm-ID: 426031 [Multi-domain]  Cd Length: 153  Bit Score: 163.60  E-value: 9.97e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450  173 WAKKISEHLLPRTRAYAEIWLDQEKVATT---DEEPILGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGF 249
Cdd:pfam01077   1 GDNVRNVTLCPGAGLCPEELLDTRPLAKAiedEFEPDYGFPYLPRKFKIAVSGCPNNCVAAHANDIGFVGVWKDGGEIGF 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 447213450  250 NLLVGGGLSIEHGNKKTYARtaseFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVETFKAEVERR 326
Cdd:pfam01077  81 NILVGGGLGRTPGAAATLKV----VPFVPEEDVLEVIEAILEVYRDHGDRENRKKERLKYLIERLGLEKFREEVEER 153
 
Name Accession Description Interval E-value
PRK13504 PRK13504
NADPH-dependent assimilatory sulfite reductase hemoprotein subunit;
5-569 0e+00

NADPH-dependent assimilatory sulfite reductase hemoprotein subunit;


Pssm-ID: 237402 [Multi-domain]  Cd Length: 569  Bit Score: 1132.98  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450   5 HPGPLVVEGKLTDAERMKLESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAMLLRC 84
Cdd:PRK13504   1 HPGPLAVEGKLSDVERIKLESNYLRGTIAEELNDGLTGGFSEDDFQLLKFHGSYQQDDRDIRAERAEQKLEPAYQFMLRC 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450  85 RLPGGVITTKQWQAIDKFAGENTiYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYES 164
Cdd:PRK13504  81 RLPGGVITPQQWLALDKLADEYG-NGTLRLTTRQTFQFHGILKKNLKPVIQTINSVLLDTLAACGDVNRNVMCTPNPYES 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450 165 QLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVAT---TDEEPILGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIA 241
Cdd:PRK13504 160 RLHAEAYEWAKKISDHLLPRTRAYAEIWLDGEKVATfsgTEEEPIYGKTYLPRKFKIAVAVPPDNDVDVYANDLGFVAIA 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450 242 ENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVETFKA 321
Cdd:PRK13504 240 ENGKLVGFNVLVGGGMGMTHGDKETYPRLADELGYVPPEDVLDVAEAVVTTQRDYGNRTDRKNARLKYTLERVGLDWFKA 319

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450 322 EVERRAGIKFEPIRPYEFTGRGDRIGWVKGIDDNWHLTLFIENGRILDYPGRPLKTGLLEIAKIHKGDFRITANQNLIIA 401
Cdd:PRK13504 320 EVERRAGKKLEPARPYEFTGRGDRLGWVEGIDGKWHLTLFIENGRIKDYPGRPLKTGLREIAKIHKGDFRLTANQNLIIA 399

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450 402 GVPESEKAKIEKIAKESGLMNAV--TPQRENSMACVSFPTCPLAMAEAERFLPSFIDNIDNLMAKHGVSDEHIVMRVTGC 479
Cdd:PRK13504 400 NVPPSDKAKIEALLREYGLIDGVeeSPLRRNSMACVALPTCGLAMAEAERYLPSFIDRIEALLAKHGLSDEHIVIRMTGC 479

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450 480 PNGCGRAMLAEVGLVGKAPGRYNLHLGGNRIGTRIPRMYKENITEPEILASLDELIGRWAKEREAGEGFGDFTVRAGIIR 559
Cdd:PRK13504 480 PNGCARPYLAEIGLVGKAPGRYNLYLGGSFNGTRLPKMYRENITEEEILATLDPLLGRWAKEREPGEGFGDFVIRAGIIR 559

                        570
                 ....*....|
gi 447213450 560 PVLDPARDLW 569
Cdd:PRK13504 560 EVLDGARDFH 569
CysI TIGR02041
sulfite reductase (NADPH) hemoprotein, beta-component; Sulfite reductase (NADPH) catalyzes a ...
 19-558 0e+00

sulfite reductase (NADPH) hemoprotein, beta-component; Sulfite reductase (NADPH) catalyzes a six electron reduction of sulfite to sulfide in prokaryotic organisms. It is a complex oligomeric enzyme composed of two different peptides with a subunit composition of alpha(8)-beta(4). The alpha component, encoded by cysJ, is a flavoprotein containing both FMN and FAD, while the beta component, encoded by cysI, is a siroheme, iron-sulfur protein. In Salmonella typhimurium and Escherichia coli, both the alpha and beta subunits of sulfite reductase are located in a unidirectional gene cluster along with phosphoadenosine phosphosulfate reductase, which catalyzes a two step reduction of PAPS to give free sulfite. In cyanobacteria and plant species, sulfite reductase ferredoxin (EC 1.8.7.1) catalyzes the reduction of sulfite to sulfide. [Central intermediary metabolism, Sulfur metabolism]


Pssm-ID: 273941 [Multi-domain]  Cd Length: 541  Bit Score: 1067.43  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450   19 ERMKLESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAMLLRCRLPGGVITTKQWQA 98
Cdd:TIGR02041   1 ERIKEESNYLRGTILEDLADPLTGGFKGDNFQLIRFHGMYQQDDRDLRAERAEQKLEPRYAMMLRCRLPGGVITPKQWLA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450   99 IDKFAGENTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQLHAEAYEWAKKIS 178
Cdd:TIGR02041  81 IDKFAREYTNYGSIRLTNRQTFQFHGILKKNLKPVHQMLHSVGLDSLATAGDVNRNVLCTSNPYESELHAEAYEWAKKIS 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450  179 EHLLPRTRAYAEIWLDQEKVATTDE-EPILGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGL 257
Cdd:TIGR02041 161 EHLLPRTRAYAEIWLDQEKVAGTEEvEPILGPTYLPRKFKTTVVIPPQNDVDVYANDLGFVAIAENGKLVGFNVLIGGGL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450  258 SIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVETFKAEVERRAGIKFEPIRPY 337
Cdd:TIGR02041 241 SMEHGNKKTYPRLASEIGFIPPEHTLAVAEAVVTTQRDFGNRTDRKNARTKYTIERMGLDTFKAEVERRAGIKFEPARPY 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450  338 EFTGRGDRIGWVKGIDDNWHLTLFIENGRILDYPGRPLKTGLLEIAKIHKGDFRITANQNLIIAGVPESEKAKIEKIAKE 417
Cdd:TIGR02041 321 EFTGRGDRIGWVKGIDGNWHLTLFIENGRILDYPDKPLKTGLLEIAKIHKGDFRITANQNLIIAGVPEGGKAKIEKLARQ 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450  418 SGLMNAVTPQRENSMACVSFPTCPLAMAEAERFLPSFIDNIDNLMAKHGVSDEHIVMRVTGCPNGCGRAMLAEVGLVGKA 497
Cdd:TIGR02041 401 YGLINAVTALRENSMACVSFPTCPLAMAEAERYLPDFIDKLDNIMAKHGLSDEEIVLRVTGCPNGCGRAMLAEIGLVGKA 480

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 447213450  498 PGRYNLHLGGNRIGTRIPRMYKENITEPEILASLDELIGRWAKEREAGEGFGDFTVRAGII 558
Cdd:TIGR02041 481 PGRYNLHLGGNRIGTRIPRLYKENITEPEILAELDELIGRWAKERKPGEGFGDFLIRAGII 541
CysI COG0155
Sulfite reductase, beta subunit (hemoprotein) [Inorganic ion transport and metabolism]; ...
 15-566 0e+00

Sulfite reductase, beta subunit (hemoprotein) [Inorganic ion transport and metabolism]; Sulfite reductase, beta subunit (hemoprotein) is part of the Pathway/BioSystem: Cysteine biosynthesis


Pssm-ID: 439925 [Multi-domain]  Cd Length: 519  Bit Score: 581.31  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450  15 LTDAERMKLESNYLR-GTIAEDLNDGLTGGFKGDNF-LLIRFHGMYQQDDrdiraeraeqklePRHAMLLRCRLPGGVIT 92
Cdd:COG0155    1 LYKYERIKREDVRSRlGTFAEQLGRFLTGEISEDDFrLRLKFHGLYQQRD-------------PDGAFMLRVRIPGGVLT 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450  93 TKQWQAIDKFAGENTiYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQL-HAEAY 171
Cdd:COG0155   68 PEQLRALADIAREYG-RGYLHLTTRQNIQLHWILLEDLPEILRELAEVGLTTIGACGDVVRNVTASPLAGVDPDeLFDVR 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450 172 EWAKKISEHLLprtrayaeiwldqekvattdEEPILgqTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNL 251
Cdd:COG0155  147 PYAEAISQHLL--------------------GHPEY--TYLPRKFKIAFSGPPEDDADVEINDLGFIAVVKEDGLVGFNV 204

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450 252 LVGGGLSIEHgnkktyaRTASEFG-YLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVETFKAEVERR-AGI 329
Cdd:COG0155  205 LVGGGLGRTP-------RLADVLGeFVPPEDLLDVAEAVVRVFRDYGDRDNRKKARLKYLVDDLGVEKFREEVEEEyLGF 277

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450 330 KFEPI-RPYEFTGRGDRIGWVKGI-DDNWHLTLFIENGRILDYPgrplKTGLLEIAKIH-KGDFRITANQNLIIAGVPES 406
Cdd:COG0155  278 PLEPApRPLPAFARWDHLGVHEQKqDGLYYVGLSVENGRITDEQ----LRALADLAERYgSGEIRLTPNQNLILADVPEE 353

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450 407 EKAKIEKIAKESGLMNAVTPQRENSMACVSFPTCPLAMAEAERFLPSFIDNIDnlmAKHG--VSDEHIVMRVTGCPNGCG 484
Cdd:COG0155  354 DLPALEAALRALGLATPPSGLRRDSIACPGLPTCKLAIAESKRLAPALADRLE---EDLDglHDDEPIRIRISGCPNSCG 430

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450 485 RAMLAEVGLVGKAP-GR---YNLHLGGNRIG-TRIPRMYKENITEPEILASLDELIGRWAKEREAGEGFGDFTVRAGI-- 557
Cdd:COG0155  431 RHYIADIGLVGKAKkGVveaYQLYLGGGLGGdARLGRKYGPKVPADEIPDALERLLEAYLAEREEGESFGDFVRRVGIep 510


                 ....*....
gi 447213450 558 IRPVLDPAR 566
Cdd:COG0155  511 LKELLYAAA 519
PLN00178 PLN00178
sulfite reductase
 6-556 1.29e-154

sulfite reductase


Pssm-ID: 177773 [Multi-domain]  Cd Length: 623  Bit Score: 456.91  E-value: 1.29e-154
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450   6 PGPLVVEGKLTDAERMKLESNYLRGTIAEDLNDGLTGgFKGDNFLLIRFHGMYQQDDRDIRAERAEQkleprhaMLLRCR 85
Cdd:PLN00178  44 KKPTTEPPKRSKVEIIKENSNFLRHPLNEELATEAPN-INEDAVQLIKFHGSYQQDNREKRGGKAYQ-------FMLRTK 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450  86 LPGGVITTKQWQAIDKFAGENTIyGSIRLTNRQTFQFHGILKKNVKPVHQ-MLHSVGlDALATANDMNRNVLCTSNPYES 164
Cdd:PLN00178 116 QPAGKVPNRLYLVMDDLADEFGI-GTLRLTTRQTFQLHGVLKKDLKTVMSsIIKNMG-STLGACGDVNRNVLAPAAPFAR 193

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450 165 QLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDE--------------------EPILGQTYLPRKFKTTVVIPP 224
Cdd:PLN00178 194 KDYLFAQELAKNIAALLAPQSGAYYDIWVDGEKIMSAEPpevtkarndnshgtnfedspEPIYGTQFLPRKFKIAVTVPG 273

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450 225 QNDIDLHANDMNFVAIA-ENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRK 303
Cdd:PLN00178 274 DNSVDILTNDIGVVVVSdEAGEPQGYNIYVGGGMGRTHRNETTFPRLADPLGYVPKEDILYAVKAIVATQRDYGRRDDRK 353

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450 304 NAKTKYTLERVGVETFKAEVERRAGIKFEPIRP---YEFTgrgDRIGWVKGIDDNWHLTLFIENGRIldypGRPLKTGLL 380
Cdd:PLN00178 354 QSRMKYLVHSWGIEKFRSVVEQYYGKKFEPFRElpeWEFK---SYLGWHEQGDGKLFYGVHVDNGRI----KGEAKKALR 426

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450 381 EIAKIHKGDFRITANQNLIIAGVPESEKAKIEKIAKESGLMNA--VTPQRENSMACVSFPTCPLAMAEAERFLPSFIDNI 458
Cdd:PLN00178 427 EVIEKYNLPVRLTPNQNLILCDIRPAWKEPITAALAAAGLLEPeeVDPLNRTAMACPALPLCPLAITEAERGIPDILKRV 506

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450 459 DNLMAKHGVS-DEHIVMRVTGCPNGCGRAMLAEVGLVGKAPGRYNLHLGGNRIGTRIPRMYKENITEPEILASLDELIGR 537
Cdd:PLN00178 507 RAMFNKVGLKyDESVVVRMTGCPNGCARPYMAELGFVGDGPNSYQIWLGGTPNQTRLAEPFMDKVKVDDLEKVLEPLFYM 586

                        570
                 ....*....|....*....
gi 447213450 538 WAKEREAGEGFGDFTVRAG 556
Cdd:PLN00178 587 WKQQRQEKESFGDFTNRVG 605
sir TIGR02042
ferredoxin-sulfite reductase; Distantly related to the iron-sulfur hemoprotein of sulfite ...
 14-556 2.58e-144

ferredoxin-sulfite reductase; Distantly related to the iron-sulfur hemoprotein of sulfite reductase (NADPH) found in Proteobacteria and Eubacteria, sulfite reductase (ferredoxin) is a cyanobacterial and plant monomeric enzyme that also catalyzes the reduction of sulfite to sulfide. [Central intermediary metabolism, Sulfur metabolism]


Pssm-ID: 131097 [Multi-domain]  Cd Length: 577  Bit Score: 428.89  E-value: 2.58e-144
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450   14 KLTDAERMKLESNYLRGTIAEDLNDGLTGgFKGDNFLLIRFHGMYQQDDRDIRAERAEQKleprHAMLLRCRLPGGVITT 93
Cdd:TIGR02042   5 KRSKVEILKERSNFLREPLNEQLLEEATH-FNEDAVQILKFHGSYQQDNRDNRGKGQEKD----YQFMLRTKNPGGYVPP 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450   94 KQWQAIDKFAGENTIyGSIRLTNRQTFQFHGILKKNVKPV-HQMLHSVGlDALATANDMNRNVLCTSNPYESQLHAE-AY 171
Cdd:TIGR02042  80 QLYLTLDDLADEYGN-GTLRATTRQTFQLHGILKKNLKTViSTIVKNLG-STLGACGDLNRNVMAPPAPFRKRPEYEfAR 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450  172 EWAKKISEHLLPRTRAYAEIWLDQEKVATTDE---------------------EPILGQTYLPRKFKTTVVIPPQNDIDL 230
Cdd:TIGR02042 158 EYADNIADLLTPQSGAYYELWLDGEKVMSAEPdpevvaarndnshgtnfadspEPLYGTQYLPRKFKIAVTVPGDNSIDL 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450  231 HANDMNFVAIA-ENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKY 309
Cdd:TIGR02042 238 FTQDIGLVVVSnERGELEGFNIYVGGGMGRTHNKEETFARLADPLGYVPKEDIYYAVKAIVATQRDYGDRDDRRHARMKY 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450  310 TLERVGVETFKAEVERRAGIKFEPIR---PYEFTgrgDRIGWVKGIDDNWHLTLFIENGRILDYPGRPLKTGLLEIAKIH 386
Cdd:TIGR02042 318 LISDWGIEKFREVVEQYFGKKIAPVRelpEFEYK---DYLGWHEQGDGKWFLGLHIDSGRVKDDGNWQLKKALREIVEKY 394

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450  387 KGDFRITANQNLIIAGVPESEKAKIEKIAKESGLMN--AVTPQRENSMACVSFPTCPLAMAEAERFLPSFIDNIDNLMAK 464
Cdd:TIGR02042 395 NLPVRLTPNQNIILYDIQPEWKRAITTVLAQRGVLQpeAIDPLNRYAMACPALPTCGLAITESERAIPGILKRIRALLEK 474

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450  465 HGVSDEHIVMRVTGCPNGCGRAMLAEVGLVGKAPGRYNLHLGGNRIGTRIPRMYKENITEPEILASLDELIGRWAKEREA 544
Cdd:TIGR02042 475 VGLPDEHFVVRMTGCPNGCARPYMAELGFVGSAPNSYQVWLGGSPNQTRLARPFIDKLKDGDLEKVLEPLFVHFKQSRQS 554

                         570
                  ....*....|..
gi 447213450  545 GEGFGDFTVRAG 556
Cdd:TIGR02042 555 GESFGDFCDRVG 566
NIR_SIR pfam01077
Nitrite and sulphite reductase 4Fe-4S domain; Sulphite and nitrite reductases are vital in the ...
 173-326 9.97e-48

Nitrite and sulphite reductase 4Fe-4S domain; Sulphite and nitrite reductases are vital in the biosynthetic assimilation of sulphur and nitrogen, respectfully. They are also both important for the dissimilation of oxidized anions for energy transduction.


Pssm-ID: 426031 [Multi-domain]  Cd Length: 153  Bit Score: 163.60  E-value: 9.97e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450  173 WAKKISEHLLPRTRAYAEIWLDQEKVATT---DEEPILGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGF 249
Cdd:pfam01077   1 GDNVRNVTLCPGAGLCPEELLDTRPLAKAiedEFEPDYGFPYLPRKFKIAVSGCPNNCVAAHANDIGFVGVWKDGGEIGF 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 447213450  250 NLLVGGGLSIEHGNKKTYARtaseFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVETFKAEVERR 326
Cdd:pfam01077  81 NILVGGGLGRTPGAAATLKV----VPFVPEEDVLEVIEAILEVYRDHGDRENRKKERLKYLIERLGLEKFREEVEER 153
PLN02431 PLN02431
ferredoxin--nitrite reductase
 81-543 7.80e-35

ferredoxin--nitrite reductase


Pssm-ID: 178050 [Multi-domain]  Cd Length: 587  Bit Score: 138.76  E-value: 7.80e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450  81 LLRCRLPGGVITTKQWQ----AIDKFaGEntiYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVl 156
Cdd:PLN02431 138 MMRLKLPNGVTTSAQTRylasVIEKY-GE---DGCADVTTRQNWQIRGVVLPDVPAILKGLEEVGLTSLQSGMDNVRNP- 212

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450 157 cTSNPYESqlhaeayewakkISEHLLPRTRAYAEIwLDQEKVATTDEEPILgqTYLPRKFKTTVVIPPQNDIDLHANDMN 236
Cdd:PLN02431 213 -VGNPLAG------------IDPHEIVDTRPYTNL-LSDYITNNGRGNPEI--TNLPRKWNVCVVGSHDLFEHPHINDLA 276

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450 237 FVAIAENGKlVGFNLLVGGGLSIehgnkKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGV 316
Cdd:PLN02431 277 YMPATKDGR-FGFNLLVGGFFSP-----KRCAEAIPLDAWVPADDVVPLCKAILEAFRDLGTRGNRQKTRMMWLIDELGV 350

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450 317 ETFKAEVERRAGikfepirpyefTGRGDRIGWVKGIDDNWHLTLFI------ENGriLDYPGRPLKTGLL------EIAK 384
Cdd:PLN02431 351 EGFRSEVEKRMP-----------NGELERAASEDLVDKKWERRDYLgvhpqkQEG--LSYVGLHVPVGRLqaadmdELAR 417

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450 385 IH----KGDFRITANQNLIIAGVPESekaKIEKIAKESgLMNAVTPQ----RENSMACVSFPTCPLAMAEAERFLPSFID 456
Cdd:PLN02431 418 LAdeygSGELRLTVEQNIIIPNVPNS---KVEALLAEP-LLQRFSPNpgllLKGLVACTGNQFCGQAIIETKARALKVTE 493

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450 457 NIDNLMAkhgvSDEHIVMRVTGCPNGCGRAMLAEVGLVG--------KAPGRYNLHLGGnRIG--TRIPRMYKENITEPE 526
Cdd:PLN02431 494 ELERLVE----VPRPVRMHWTGCPNSCGQVQVADIGFMGcmardengKAVEGADIFVGG-RVGsdSHLAEEYKKGVPCDE 568

                        490
                 ....*....|....*....
gi 447213450 527 ILASLDE-LIGRW-AKERE 543
Cdd:PLN02431 569 LVPVVADiLIEEFgAKERE 587
nirA PRK09566
ferredoxin-nitrite reductase; Reviewed
 81-507 8.92e-33

ferredoxin-nitrite reductase; Reviewed


Pssm-ID: 236572 [Multi-domain]  Cd Length: 513  Bit Score: 131.67  E-value: 8.92e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450  81 LLRCRLPGGVITTKQWQAIDKFA---GENtiyGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVlc 157
Cdd:PRK09566  67 MLRLRVPNGILTSEQLRVLASIVqryGDD---GSADITTRQNLQLRGILLEDLPEILNRLKAVGLTSVQSGMDNVRNI-- 141

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450 158 TSNPYESQLHAEAY---EWAKKISEHLlprtrayaeiwldqekvaTTDEEPILGQTYLPRKFKTTVVIPPQNDIDLHAND 234
Cdd:PRK09566 142 TGSPVAGIDPDELIdtrPLTQKLQDML------------------TNNGEGNPEFSNLPRKFNIAIAGGRDNSVHAEIND 203

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450 235 MNFVAIAENGKLvGFNLLVGGGLSiehGNKKTYArtasefgyLPL------EHTLAVAEAVVTTQRDWGNRTDRKNAKTK 308
Cdd:PRK09566 204 IAFVPAYKDGVL-GFNVLVGGFFS---SQRCAYA--------IPLnawvkpDEVVRLCRAILEVYRDNGLRANRQKGRLM 271

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450 309 YTLERVGVETFKAEVERRAGIKFEPIRPyeftgrGDRIGWvkgiDDNWHLTLFIENGRILDY-----P-GRPLKTGLLEI 382
Cdd:PRK09566 272 WLIDEWGIEKFRAAVEAQFGPPLLTAAP------GDEIDW----EKRDHIGVHPQKQAGLNYvglhvPvGRLYAEDMFEL 341

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450 383 AKIHK----GDFRITANQNLIIAGVPESekaKIEKIAKESgLMNAVTPQREN----SMACVSFPTCPLAMAEA-ERflps 453
Cdd:PRK09566 342 ARLAEvygsGEIRLTVEQNVIIPNIPDE---NLETFLAEP-LLQKFSLEPGPlargLVSCTGNQYCNFALIETkNR---- 413

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 447213450 454 fidnidNLMAKHGVSDE-----HIVMRVTGCPNGCGRAMLAEVGLVG---KAPGR----YNLHLGG 507
Cdd:PRK09566 414 ------ALALAKELDAEldlpqPVRIHWTGCPNSCGQPQVADIGLMGtkaRKNGKtvegVDIYMGG 473
nirA PRK09567
NirA family protein;
13-554 1.99e-32

NirA family protein;


Pssm-ID: 236573 [Multi-domain]  Cd Length: 593  Bit Score: 131.68  E-value: 1.99e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450  13 GKLTDAERMKLESNYLrgtiaeDLNDGL-----TGGF-KGDNFLLIRFHGMYQ----QDdrdiraeraeqkleprhAMLL 82
Cdd:PRK09567  63 KKLCDQEKWKREENPF------DAWDRLkaqaaAGAFpKPADNFRWKYHGLFYvapaQD-----------------SYMC 119

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450  83 RCRLPGGVITTKQWQAI----DKFAGentiyGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVlcT 158
Cdd:PRK09567 120 RLRIPNGILTHWQFAGLadlaDRHGG-----GYSHVTTRANLQLREIPPEHAVPVLEGLVDLGLTARGSGADNIRNV--T 192

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450 159 SNPyesqlhaeayewAKKISEHLLPRTRAYAEIWldqekvattdEEPILGQ--TY-LPRKFKTTV----VIPPQNDidlh 231
Cdd:PRK09567 193 GSP------------TAGIDPQELLDTRPYAREW----------HHHILNDrsLYgLPRKFNVAFdgggRIATLED---- 246

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450 232 ANDMNFVA--IAENGKL---VGFNLLVGG--GlsieHgnkKTYARTAsefGY-LPLEHTLAVAEAVVTTQRDWGNRTDRK 303
Cdd:PRK09567 247 TNDIGFQAvrVLEGAGVapgVYFRLVLGGitG----H---KDFARDT---GVlLRPEEATAVADAIVRVFIENGDRTNRK 316

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450 304 NAKTKYTLERVGVETFKAEVERRAGIKFEPIRPYEFTGRG--DRIGWV-----KGIDDNWhLTLFIENGRILDYPGRplk 376
Cdd:PRK09567 317 KARLKYVLDAWGFDKFLEAVEEKLGRPLTRVPAEAVAPRPaaDRFAHVgvhpqKQPGLNW-IGVVLPVGRLTTDQMR--- 392

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450 377 tGLLEIAKIH-KGDFRITANQNLIIAGVPESEKAKIEKIAKESGLMNAVTPQRENSMACVSFPTCPLAMAEAERFLPSFI 455
Cdd:PRK09567 393 -GLAKIAARYgDGEIRLTVWQNLLISGVPDADVAAVEAAIEALGLTTEASSIRAGLVACTGNAGCKFAAADTKGHALAIA 471

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450 456 DNIDNLMAkhgvSDEHIVMRVTGCPNGCGRAMLAEVGLVG-KAPGR-------YNLHLGGN-----RIGTRIPRmykeNI 522
Cdd:PRK09567 472 DYCEPRVA----LDQPVNIHLTGCHHSCAQHYIGDIGLIGaKVAVSegdtvegYHIVVGGGfgedaAIGREVFR----DV 543

                        570       580       590
                 ....*....|....*....|....*....|...
gi 447213450 523 TEPEILASLDELIGRWAKEREA-GEGFGDFTVR 554
Cdd:PRK09567 544 KAEDAPRLVERLLRAYLAHRQGpDETFQAFTRR 576
CobG TIGR02435
precorrin-3B synthase; An iron-sulfur protein. An oxygen atom from dioxygen is incorporated ...
 81-500 1.82e-18

precorrin-3B synthase; An iron-sulfur protein. An oxygen atom from dioxygen is incorporated into the macrocycle at C-20. In the aerobic cobalamin biosythesis pathway, four enzymes are involved in the conversion of precorrin-3A to precorrin-6A. The first of the four steps is carried out by EC 1.14.13.83, precorrin-3B synthase (CobG), yielding precorrin-3B as the product. This is followed by three methylation reactions, which introduce a methyl group at C-17 (CobJ; EC 2.1.1.131), C-11 (CobM; EC 2.1.1.133) and C-1 (CobF; EC 2.1.1.152) of the macrocycle, giving rise to precorrin-4, precorrin-5 and precorrin-6A, respectively. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin]


Pssm-ID: 274131 [Multi-domain]  Cd Length: 390  Bit Score: 87.54  E-value: 1.82e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450   81 LLRCRLPGGVITTKQWQAIDKFAgENTIYGSIRLTNRQTFQFHGIlKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSn 160
Cdd:TIGR02435  19 LVRVRLPGGRLTPAQAIGLADLA-ERLGNGIIEVTARGNLQLRGL-TADHDALSQALLAAGLGAAGAAADDIRNIEVSP- 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450  161 pyesqlhaeayewAKKISEHLLPRTRAYAEIWLdqekvATTDEEPILGQtyLPRKFktTVVIPPQNDIDL--HANDMNFV 238
Cdd:TIGR02435  96 -------------LAGIDPGEIADTRPLAAELR-----AALENERALLE--LPPKF--SVAIDGGGRLVLlgDTADVRLQ 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450  239 AIaENGKLVGFNLLVGGglsiehgnKKTYARTAsefGYLPLEHTLAVAEAVVTTQRDWGNRtdrknAKTKYTLERVGVET 318
Cdd:TIGR02435 154 AL-TTGAGVAWVVSLAG--------ISTSARSL---VTVAPDAAVPVAVALLRVFVELGGA-----ARGRDLDDAFLFAL 216

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450  319 FKAEVERRAGIKFEPIR---PYEFTGRGDRIGWVKGIDDNWHLTLFIENGRIldyPGRPLKtGLLEIAKIH-KGDFRITA 394
Cdd:TIGR02435 217 ALELVEDSRPLIPDAAEgeaPRPAVDAAAPLGLHPQGDAGVTLGAGLALGQL---TAAQLR-GLAQLAQALgDGDLRLTP 292

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447213450  395 NQNLIIAGVPESEKAKIEKIAKESGLMNAVTPQRENSMACVSFPTCPLAMAE----AERFLPSFIDNIDnlmakhgvsde 470
Cdd:TIGR02435 293 WRALLVLGLPPERADAAQRALAALGLVTSASDPRARIIACTGAPGCASALADtradAEALAAYCEPTAP----------- 361

                         410       420       430
                  ....*....|....*....|....*....|
gi 447213450  471 hIVMRVTGCPNGCGRAMLAEVGLVGKAPGR 500
Cdd:TIGR02435 362 -ITVHLSGCAKGCAHPGPAAITLVAAGAGY 390
NIR_SIR_ferr pfam03460
Nitrite/Sulfite reductase ferredoxin-like half domain; Sulfite and Nitrite reductases are key ...
 82-140 3.38e-11

Nitrite/Sulfite reductase ferredoxin-like half domain; Sulfite and Nitrite reductases are key to both biosynthetic assimilation of sulfur and nitrogen and dissimilation of oxidized anions for energy transduction. Two copies of this repeat are found in Nitrite and Sulfite reductases and form a single structural domain.


Pssm-ID: 377044 [Multi-domain]  Cd Length: 67  Bit Score: 58.69  E-value: 3.38e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 447213450   82 LRCRLPGGVITTKQWQAIDKFAGEntiYGS--IRLTNRQTFQFHGILKKNVKPVHQMLHSV 140
Cdd:pfam03460  10 VRVRVPGGRLTAEQLRALADIAEK---YGDgeIRLTTRQNLELHGVPEEDLPELLEELAEA 67
NIR_SIR_ferr pfam03460
Nitrite/Sulfite reductase ferredoxin-like half domain; Sulfite and Nitrite reductases are key ...
 353-417 6.67e-10

Nitrite/Sulfite reductase ferredoxin-like half domain; Sulfite and Nitrite reductases are key to both biosynthetic assimilation of sulfur and nitrogen and dissimilation of oxidized anions for energy transduction. Two copies of this repeat are found in Nitrite and Sulfite reductases and form a single structural domain.


Pssm-ID: 377044 [Multi-domain]  Cd Length: 67  Bit Score: 55.23  E-value: 6.67e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 447213450  353 DDNWHLTLFIENGRIldypGRPLKTGLLEIAKIH-KGDFRITANQNLIIAGVPESEKAKIEKIAKE 417
Cdd:pfam03460   5 DGDYMVRVRVPGGRL----TAEQLRALADIAEKYgDGEIRLTTRQNLELHGVPEEDLPELLEELAE 66
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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