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Conserved domains on  [gi|447177759|ref|WP_001255015|]
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MULTISPECIES: LysR family transcriptional regulator [Bacteria]

Protein Classification

LysR family transcriptional regulator( domain architecture ID 11426483)

LysR family transcriptional regulator containing an N-terminal HTH (helix-turn-helix) DNA-binding domain and a C-terminal substrate binding domain, which is structurally homologous to the type 2 periplasmic-binding (PBP2) fold proteins

CATH:  3.40.190.10
Gene Ontology:  GO:0003700|GO:0003677|GO:0006355
PubMed:  19047729|8257110|15808743
SCOP:  4000316

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LysR COG0583
DNA-binding transcriptional regulator, LysR family [Transcription];
19-101 3.24e-24

DNA-binding transcriptional regulator, LysR family [Transcription];


:

Pssm-ID: 440348 [Multi-domain]  Cd Length: 256  Bit Score: 91.85  E-value: 3.24e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447177759  19 IPLISLVQFIAVAEHLNFRHAAKALGISQSSVSARVKALEDNLGVLLFERHARGVRLTDAGRHFMERVTAGVDQLDHAVK 98
Cdd:COG0583    1 MDLRQLRAFVAVAEEGSFTAAAERLGVSQPAVSRQIRRLEEELGVPLFERTGRGLRLTEAGERLLERARRILAELEEAEA 80


                 ...
gi 447177759  99 TAE 101
Cdd:COG0583   81 ELR 83
 
Name Accession Description Interval E-value
LysR COG0583
DNA-binding transcriptional regulator, LysR family [Transcription];
19-101 3.24e-24

DNA-binding transcriptional regulator, LysR family [Transcription];


Pssm-ID: 440348 [Multi-domain]  Cd Length: 256  Bit Score: 91.85  E-value: 3.24e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447177759  19 IPLISLVQFIAVAEHLNFRHAAKALGISQSSVSARVKALEDNLGVLLFERHARGVRLTDAGRHFMERVTAGVDQLDHAVK 98
Cdd:COG0583    1 MDLRQLRAFVAVAEEGSFTAAAERLGVSQPAVSRQIRRLEEELGVPLFERTGRGLRLTEAGERLLERARRILAELEEAEA 80


                 ...
gi 447177759  99 TAE 101
Cdd:COG0583   81 ELR 83
HTH_1 pfam00126
Bacterial regulatory helix-turn-helix protein, lysR family;
24-80 1.53e-21

Bacterial regulatory helix-turn-helix protein, lysR family;


Pssm-ID: 459683 [Multi-domain]  Cd Length: 60  Bit Score: 79.74  E-value: 1.53e-21
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 447177759   24 LVQFIAVAEHLNFRHAAKALGISQSSVSARVKALEDNLGVLLFERHARGVRLTDAGR 80
Cdd:pfam00126   4 LRLFVAVAETGSFTAAAERLGLSQPAVSRQIKRLEEELGVPLFERTTRGVRLTEAGE 60
PRK11242 PRK11242
DNA-binding transcriptional regulator CynR; Provisional
 27-94 6.76e-17

DNA-binding transcriptional regulator CynR; Provisional


Pssm-ID: 183051 [Multi-domain]  Cd Length: 296  Bit Score: 73.07  E-value: 6.76e-17
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 447177759  27 FIAVAEHLNFRHAAKALGISQSSVSARVKALEDNLGVLLFERHARGVRLTDAGRHFMERVTAGVDQLD 94
Cdd:PRK11242   9 FLAVAEHGNFTRAAEALHVSQPTLSQQIRQLEESLGVQLFDRSGRTVRLTDAGEVYLRYARRALQDLE 76
HTH_MARR smart00347
helix_turn_helix multiple antibiotic resistance protein;
22-97 4.46e-04

helix_turn_helix multiple antibiotic resistance protein;


Pssm-ID: 197670 [Multi-domain]  Cd Length: 101  Bit Score: 36.42  E-value: 4.46e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447177759    22 ISLVQF-----IAVAEHLNFRHAAKALGISQSSVSARVKALEDNlGVLLFERHARG-----VRLTDAGRHFMERVTAGVD 91
Cdd:smart00347   8 LTPTQFlvlriLYEEGPLSVSELAKRLGVSPSTVTRVLDRLEKK-GLVRREPSPEDrrsvlVSLTEEGRELIEQLLEARS 86


                   ....*.
gi 447177759    92 QLDHAV 97
Cdd:smart00347  87 ETLAEL 92
 
Name Accession Description Interval E-value
LysR COG0583
DNA-binding transcriptional regulator, LysR family [Transcription];
19-101 3.24e-24

DNA-binding transcriptional regulator, LysR family [Transcription];


Pssm-ID: 440348 [Multi-domain]  Cd Length: 256  Bit Score: 91.85  E-value: 3.24e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447177759  19 IPLISLVQFIAVAEHLNFRHAAKALGISQSSVSARVKALEDNLGVLLFERHARGVRLTDAGRHFMERVTAGVDQLDHAVK 98
Cdd:COG0583    1 MDLRQLRAFVAVAEEGSFTAAAERLGVSQPAVSRQIRRLEEELGVPLFERTGRGLRLTEAGERLLERARRILAELEEAEA 80


                 ...
gi 447177759  99 TAE 101
Cdd:COG0583   81 ELR 83
HTH_1 pfam00126
Bacterial regulatory helix-turn-helix protein, lysR family;
24-80 1.53e-21

Bacterial regulatory helix-turn-helix protein, lysR family;


Pssm-ID: 459683 [Multi-domain]  Cd Length: 60  Bit Score: 79.74  E-value: 1.53e-21
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 447177759   24 LVQFIAVAEHLNFRHAAKALGISQSSVSARVKALEDNLGVLLFERHARGVRLTDAGR 80
Cdd:pfam00126   4 LRLFVAVAETGSFTAAAERLGLSQPAVSRQIKRLEEELGVPLFERTTRGVRLTEAGE 60
PRK11242 PRK11242
DNA-binding transcriptional regulator CynR; Provisional
 27-94 6.76e-17

DNA-binding transcriptional regulator CynR; Provisional


Pssm-ID: 183051 [Multi-domain]  Cd Length: 296  Bit Score: 73.07  E-value: 6.76e-17
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 447177759  27 FIAVAEHLNFRHAAKALGISQSSVSARVKALEDNLGVLLFERHARGVRLTDAGRHFMERVTAGVDQLD 94
Cdd:PRK11242   9 FLAVAEHGNFTRAAEALHVSQPTLSQQIRQLEESLGVQLFDRSGRTVRLTDAGEVYLRYARRALQDLE 76
PRK09986 PRK09986
LysR family transcriptional regulator;
18-96 8.91e-17

LysR family transcriptional regulator;


Pssm-ID: 182183 [Multi-domain]  Cd Length: 294  Bit Score: 72.83  E-value: 8.91e-17
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 447177759  18 RIPLISLVQFIAVAEHLNFRHAAKALGISQSSVSARVKALEDNLGVLLFERHARGVRLTDAGRHFMERVTAGVDQLDHA 96
Cdd:PRK09986   6 RIDLKLLRYFLAVAEELHFGRAAARLNISQPPLSIHIKELEDQLGTPLFIRHSRSVVLTHAGKILMEESRRLLDNAEQS 84
PRK11139 PRK11139
DNA-binding transcriptional activator GcvA; Provisional
 20-96 2.39e-16

DNA-binding transcriptional activator GcvA; Provisional


Pssm-ID: 182990 [Multi-domain]  Cd Length: 297  Bit Score: 71.80  E-value: 2.39e-16
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 447177759  20 PLISLVQFIAVAEHLNFRHAAKALGISQSSVSARVKALEDNLGVLLFERHARGVRLTDAGRHFMERVTAGVDQLDHA 96
Cdd:PRK11139   7 PLNALRAFEAAARHLSFTRAAEELFVTQAAVSHQIKALEDFLGLKLFRRRNRSLLLTEEGQRYFLDIREIFDQLAEA 83
PRK09906 PRK09906
DNA-binding transcriptional regulator HcaR; Provisional
 27-100 6.65e-16

DNA-binding transcriptional regulator HcaR; Provisional


Pssm-ID: 182137 [Multi-domain]  Cd Length: 296  Bit Score: 70.57  E-value: 6.65e-16
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 447177759  27 FIAVAEHLNFRHAAKALGISQSSVSARVKALEDNLGVLLFERHARGVRLTDAGRHFMERVTAGVDQLDHAVKTA 100
Cdd:PRK09906   9 FVAVAEELNFTKAAEKLHTAQPSLSQQIKDLENCVGVPLLVRDKRKVALTAAGEVFLQDARAILEQAEKAKLRA 82
PRK10094 PRK10094
HTH-type transcriptional activator AllS;
27-95 4.15e-14

HTH-type transcriptional activator AllS;


Pssm-ID: 182237 [Multi-domain]  Cd Length: 308  Bit Score: 65.60  E-value: 4.15e-14
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 447177759  27 FIAVAEHLNFRHAAKALGISQSSVSARVKALEDNLGVLLFERHARGVRLTDAGRHFMERVTAGVDQLDH 95
Cdd:PRK10094  10 FIAVAETGSFSKAAERLCKTTATISYRIKLLEENTGVALFFRTTRSVTLTAAGEHLLSQARDWLSWLES 78
PRK10086 PRK10086
DNA-binding transcriptional regulator DsdC;
21-101 6.90e-14

DNA-binding transcriptional regulator DsdC;


Pssm-ID: 182231 [Multi-domain]  Cd Length: 311  Bit Score: 65.02  E-value: 6.90e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447177759  21 LISLVQFIAVAEHLNFRHAAKALGISQSSVSARVKALEDNLGVLLFERHARGVRLTDAGRHFMERVTAGVDQLDHAV--- 97
Cdd:PRK10086  16 LSKLHTFEVAARHQSFALAADELSLTPSAVSHRINQLEEELGIKLFVRSHRKVELTEEGKRVFWALKSSLDTLNQEIldi 95


                 ....
gi 447177759  98 KTAE 101
Cdd:PRK10086  96 KNQE 99
PRK11151 PRK11151
DNA-binding transcriptional regulator OxyR; Provisional
 28-79 4.79e-13

DNA-binding transcriptional regulator OxyR; Provisional


Pssm-ID: 182999 [Multi-domain]  Cd Length: 305  Bit Score: 62.74  E-value: 4.79e-13
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 447177759  28 IAVAEHLNFRHAAKALGISQSSVSARVKALEDNLGVLLFERHARGVRLTDAG 79
Cdd:PRK11151  10 VALAEHRHFRRAADSCHVSQPTLSGQIRKLEDELGVMLLERTSRKVLFTQAG 61
PRK11074 PRK11074
putative DNA-binding transcriptional regulator; Provisional
 29-84 9.34e-13

putative DNA-binding transcriptional regulator; Provisional


Pssm-ID: 182948 [Multi-domain]  Cd Length: 300  Bit Score: 61.88  E-value: 9.34e-13
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 447177759  29 AVAEHLNFRHAAKALGISQSSVSARVKALEDNLGVLLFERHARGVRLTDAGRHFME 84
Cdd:PRK11074  12 AVARTGSFSAAAQELHRVPSAVSYTVRQLEEWLAVPLFERRHRDVELTPAGEWFVK 67
PRK13348 PRK13348
HTH-type transcriptional regulator ArgP;
27-80 2.67e-11

HTH-type transcriptional regulator ArgP;


Pssm-ID: 237357 [Multi-domain]  Cd Length: 294  Bit Score: 57.67  E-value: 2.67e-11
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 447177759  27 FIAVAEHLNFRHAAKALGISQSSVSARVKALEDNLGVLLFERhARGVRLTDAGR 80
Cdd:PRK13348  10 LAAVVETGSFERAARRLHVTPSAVSQRIKALEESLGQPLLVR-GRPCRPTPAGQ 62
PRK09791 PRK09791
LysR family transcriptional regulator;
15-85 1.47e-10

LysR family transcriptional regulator;


Pssm-ID: 182077 [Multi-domain]  Cd Length: 302  Bit Score: 55.92  E-value: 1.47e-10
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 447177759  15 LSGRIPLISLVQFIAVAEHLNFRHAAKALGISQSSVSARVKALEDNLGVLLFERHARGVRLTDAGRHFMER 85
Cdd:PRK09791   1 MAFQVKIHQIRAFVEVARQGSIRGASRMLNMSQPALTKSIQELEEGLAAQLFFRRSKGVTLTDAGESFYQH 71
rbcR CHL00180
LysR transcriptional regulator; Provisional
 24-97 1.51e-10

LysR transcriptional regulator; Provisional


Pssm-ID: 177082 [Multi-domain]  Cd Length: 305  Bit Score: 55.80  E-value: 1.51e-10
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 447177759  24 LVQFIAVAEHLNFRHAAKALGISQSSVSARVKALEDNLGVLLFERHARGVRLTDAGRHFM---ERVTAGVDQLDHAV 97
Cdd:CHL00180  10 LRILKAIATEGSFKKAAESLYISQPAVSLQIKNLEKQLNIPLFDRSKNKASLTEAGELLLrygNRILALCEETCRAL 86
PRK03635 PRK03635
ArgP/LysG family DNA-binding transcriptional regulator;
29-80 2.76e-10

ArgP/LysG family DNA-binding transcriptional regulator;


Pssm-ID: 235144 [Multi-domain]  Cd Length: 294  Bit Score: 55.16  E-value: 2.76e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 447177759  29 AVAEHLNFRHAAKALGISQSSVSARVKALEDNLGVLLFERhARGVRLTDAGR 80
Cdd:PRK03635  12 AVVREGSFERAAQKLHITQSAVSQRIKALEERVGQVLLVR-TQPCRPTEAGQ 62
PRK03601 PRK03601
HTH-type transcriptional regulator HdfR;
27-79 7.12e-10

HTH-type transcriptional regulator HdfR;


Pssm-ID: 235137 [Multi-domain]  Cd Length: 275  Bit Score: 53.87  E-value: 7.12e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 447177759  27 FIAVAEHLNFRHAAKALGISQSSVSARVKALEDNLGVLLFERHARGVRLTDAG 79
Cdd:PRK03601   9 FLEVSRTRHFGRAAESLYLTQSAVSFRIRQLENQLGVNLFTRHRNNIRLTAAG 61
PRK12684 PRK12684
CysB family HTH-type transcriptional regulator;
29-93 5.35e-09

CysB family HTH-type transcriptional regulator;


Pssm-ID: 237173 [Multi-domain]  Cd Length: 313  Bit Score: 51.52  E-value: 5.35e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 447177759  29 AVAEHLNFRHAAKALGISQSSVSARVKALEDNLGVLLFERHARGVR-LTDAGRHFM---ERVTAGVDQL 93
Cdd:PRK12684  12 AVRQNFNLTEAAKALYTSQPGVSKAIIELEDELGVEIFTRHGKRLRgLTEPGRIILasvERILQEVENL 80
PRK10341 PRK10341
transcriptional regulator TdcA;
23-97 6.75e-09

transcriptional regulator TdcA;


Pssm-ID: 182391 [Multi-domain]  Cd Length: 312  Bit Score: 51.40  E-value: 6.75e-09
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 447177759  23 SLVQFIAVAEHLNFRHAAKALGISQSSVSARVKALEDNLGVLLFERHARGVRLTDAGRHFMERVTAGVDQLDHAV 97
Cdd:PRK10341  11 HLVVFQEVIRSGSIGSAAKELGLTQPAVSKIINDIEDYFGVELIVRKNTGVTLTPAGQVLLSRSESITREMKNMV 85
PRK12682 PRK12682
transcriptional regulator CysB-like protein; Reviewed
 29-93 6.92e-09

transcriptional regulator CysB-like protein; Reviewed


Pssm-ID: 183679 [Multi-domain]  Cd Length: 309  Bit Score: 51.15  E-value: 6.92e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 447177759  29 AVAEHLNFRHAAKALGISQSSVSARVKALEDNLGVLLFERHA-RGVRLTDAGRHFM---ERVTAGVDQL 93
Cdd:PRK12682  12 AVRRNLNLTEAAKALHTSQPGVSKAIIELEEELGIEIFIRHGkRLKGLTEPGKAVLdviERILREVGNI 80
PRK12683 PRK12683
transcriptional regulator CysB-like protein; Reviewed
 29-76 4.52e-08

transcriptional regulator CysB-like protein; Reviewed


Pssm-ID: 237172 [Multi-domain]  Cd Length: 309  Bit Score: 48.89  E-value: 4.52e-08
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 447177759  29 AVAEHLNFRHAAKALGISQSSVSARVKALEDNLGVLLFERhaRGVRLT 76
Cdd:PRK12683  12 AVRQNFNLTEVANALYTSQSGVSKQIKDLEDELGVEIFIR--RGKRLT 57
PRK10082 PRK10082
hypochlorite stress DNA-binding transcriptional regulator HypT;
24-94 1.40e-07

hypochlorite stress DNA-binding transcriptional regulator HypT;


Pssm-ID: 182228 [Multi-domain]  Cd Length: 303  Bit Score: 47.36  E-value: 1.40e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 447177759  24 LVQFIAVAEHLNFRHAAKALGISQSSVSARVKALEDNLGVLLFERHARGVRLTDAGRHFMERVTAGVDQLD 94
Cdd:PRK10082  16 LYDFLTLEKCRNFSQAAVSRNVSQPAFSRRIRALEQAIGVELFNRQVTPLQLSEQGKIFHSQIRHLLQQLE 86
PRK10632 PRK10632
HTH-type transcriptional activator AaeR;
27-80 8.15e-07

HTH-type transcriptional activator AaeR;


Pssm-ID: 182601 [Multi-domain]  Cd Length: 309  Bit Score: 45.14  E-value: 8.15e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 447177759  27 FIAVAEHLNFRHAAKALGISQSSVSARVKALEDNLGVLLFERHARGVRLTDAGR 80
Cdd:PRK10632  10 FAKVVEFGSFTAAARQLQMSVSSISQTVSKLEDELQVKLLNRSTRSIGLTEAGR 63
PRK14997 PRK14997
LysR family transcriptional regulator; Provisional
 21-88 1.61e-06

LysR family transcriptional regulator; Provisional


Pssm-ID: 184959 [Multi-domain]  Cd Length: 301  Bit Score: 44.60  E-value: 1.61e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 447177759  21 LISLVQFIAVAEHLNFRHAAKALGISQSSVSARVKALEDNLGVLLFERHARGVRLTDAGRHFMERVTA 88
Cdd:PRK14997   4 LNDFAWFVHVVEEGGFAAAGRALDEPKSKLSRRIAQLEERLGVRLIQRTTRQFNVTEVGQTFYEHCKA 71
PRK12680 PRK12680
LysR family transcriptional regulator;
21-88 2.45e-06

LysR family transcriptional regulator;


Pssm-ID: 183677 [Multi-domain]  Cd Length: 327  Bit Score: 43.84  E-value: 2.45e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447177759  21 LISLVQFIAVAE-HLNFRHAAKALGISQSSVSARVKALEDNLGVLLFERHARGVR-LTDAGRHFMERVTA 88
Cdd:PRK12680   3 LTQLRYLVAIADaELNITLAAARVHATQPGLSKQLKQLEDELGFLLFVRKGRSLEsVTPAGVEVIERARA 72
PRK09801 PRK09801
LysR family transcriptional regulator;
20-84 3.87e-06

LysR family transcriptional regulator;


Pssm-ID: 182085 [Multi-domain]  Cd Length: 310  Bit Score: 43.49  E-value: 3.87e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 447177759  20 PLISLVQFIAVAEHL-NFRHAAKALGISQSSVSARVKALEDNLGVLLFERHARGVRLTDAGRHFME 84
Cdd:PRK09801   6 PLAKDLQVLVEIVHSgSFSAAAATLGQTPAFVTKRIQILENTLATTLLNRSARGVALTESGQRCYE 71
PRK11716 PRK11716
HTH-type transcriptional activator IlvY;
45-84 3.95e-06

HTH-type transcriptional activator IlvY;


Pssm-ID: 236961 [Multi-domain]  Cd Length: 269  Bit Score: 43.27  E-value: 3.95e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 447177759  45 ISQSSVSARVKALEDNLGVLLFERHARGVRLTDAGRHFME 84
Cdd:PRK11716   3 VSPSTLSRQIQRLEEELGQPLFVRDNRSVTLTEAGEELRP 42
PRK15092 PRK15092
DNA-binding transcriptional repressor LrhA; Provisional
 27-79 5.82e-06

DNA-binding transcriptional repressor LrhA; Provisional


Pssm-ID: 237907 [Multi-domain]  Cd Length: 310  Bit Score: 42.71  E-value: 5.82e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 447177759  27 FIAVAEHLNFRHAAKALGISQSSVSARVKALEDNLGVLLFERHARGVRLTDAG 79
Cdd:PRK15092  19 FVAVADLNTFAAAAAAVCRTQSAVSQQMQRLEQLVGKELFARHGRNKLLTEHG 71
cysB PRK12681
HTH-type transcriptional regulator CysB;
30-80 6.00e-06

HTH-type transcriptional regulator CysB;


Pssm-ID: 183678 [Multi-domain]  Cd Length: 324  Bit Score: 42.96  E-value: 6.00e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 447177759  30 VAEH-LNFRHAAKALGISQSSVSARVKALEDNLGVLLFERHARGV-RLTDAGR 80
Cdd:PRK12681  12 VVNHnLNVSATAEGLYTSQPGISKQVRMLEDELGIQIFARSGKHLtQVTPAGE 64
PRK10837 PRK10837
putative DNA-binding transcriptional regulator; Provisional
 18-92 3.00e-05

putative DNA-binding transcriptional regulator; Provisional


Pssm-ID: 182768 [Multi-domain]  Cd Length: 290  Bit Score: 40.83  E-value: 3.00e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 447177759  18 RIPLISLVQFIAVAEHLNFRHAAKALGISQSSVSARVKALEDNLGVLLFERHARGVRLTDAGRHFMERVTAGVDQ 92
Cdd:PRK10837   2 HITLRQLEVFAEVLKSGSTTQASVMLALSQSAVSAALTDLEGQLGVQLFDRVGKRLVVNEHGRLLYPRALALLEQ 76
nhaR PRK11062
transcriptional activator NhaR; Provisional
 33-79 7.73e-05

transcriptional activator NhaR; Provisional


Pssm-ID: 182938 [Multi-domain]  Cd Length: 296  Bit Score: 39.61  E-value: 7.73e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 447177759  33 HLNFRH---------------AAKALGISQSSVSARVKALEDNLGVLLFERHARGVRLTDAG 79
Cdd:PRK11062   3 HINYNHlyyfwmvckegsvvgAAEALFLTPQTITGQIKALEERLQGKLFKRKGRGLEPTELG 64
MntR COG1321
Mn-dependent transcriptional regulator MntR, DtxR family [Transcription];
40-86 1.87e-04

Mn-dependent transcriptional regulator MntR, DtxR family [Transcription];


Pssm-ID: 440932 [Multi-domain]  Cd Length: 135  Bit Score: 37.88  E-value: 1.87e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 447177759  40 AKALGISQSSVSARVKALEDNlGVLLFERHaRGVRLTDAGRHFMERV 86
Cdd:COG1321   31 AERLGVSPPSVTEMLKKLEEK-GLVEYEPY-GGITLTEEGRELALRI 75
ModE COG2005
DNA-binding transcriptional regulator ModE (molybdenum-dependent) [Transcription];
29-85 2.00e-04

DNA-binding transcriptional regulator ModE (molybdenum-dependent) [Transcription];


Pssm-ID: 441608 [Multi-domain]  Cd Length: 118  Bit Score: 37.49  E-value: 2.00e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 447177759  29 AVAEHLNFRHAAKALGISQSSVSARVKALEDNLGVLLFERHARGV-----RLTDAGRHFMER 85
Cdd:COG2005   29 AIDETGSISAAAKAMGMSYKRAWDLIDAMNNLLGEPLVERQTGGKggggaRLTPEGRRLLAL 90
cbl PRK12679
HTH-type transcriptional regulator Cbl;
29-75 3.21e-04

HTH-type transcriptional regulator Cbl;


Pssm-ID: 183676 [Multi-domain]  Cd Length: 316  Bit Score: 37.87  E-value: 3.21e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 447177759  29 AVAEHLNFRHAAKALGISQSSVSARVKALEDNLGVLLFERhaRGVRL 75
Cdd:PRK12679  12 AARQDYNLTEVANMLFTSQSGVSRHIRELEDELGIEIFIR--RGKRL 56
HTH_MARR smart00347
helix_turn_helix multiple antibiotic resistance protein;
22-97 4.46e-04

helix_turn_helix multiple antibiotic resistance protein;


Pssm-ID: 197670 [Multi-domain]  Cd Length: 101  Bit Score: 36.42  E-value: 4.46e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447177759    22 ISLVQF-----IAVAEHLNFRHAAKALGISQSSVSARVKALEDNlGVLLFERHARG-----VRLTDAGRHFMERVTAGVD 91
Cdd:smart00347   8 LTPTQFlvlriLYEEGPLSVSELAKRLGVSPSTVTRVLDRLEKK-GLVRREPSPEDrrsvlVSLTEEGRELIEQLLEARS 86


                   ....*.
gi 447177759    92 QLDHAV 97
Cdd:smart00347  87 ETLAEL 92
Rfk COG1339
Archaeal CTP-dependent riboflavin kinase [Coenzyme transport and metabolism]; Archaeal ...
 40-86 5.71e-04

Archaeal CTP-dependent riboflavin kinase [Coenzyme transport and metabolism]; Archaeal CTP-dependent riboflavin kinase is part of the Pathway/BioSystem: Riboflavin/FAD biosynthesis


Pssm-ID: 440950 [Multi-domain]  Cd Length: 219  Bit Score: 37.13  E-value: 5.71e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 447177759  40 AKALGISQSSVSARVKALEDNlGVLLFERHARG--VRLTDAGRHFMERV 86
Cdd:COG1339   29 AKRLGISQQTASRRLQELEDA-GLIERDLVGDGqwVKITEKGEELLRRE 76
leuO PRK09508
leucine transcriptional activator; Reviewed
 24-76 2.08e-03

leucine transcriptional activator; Reviewed


Pssm-ID: 181918 [Multi-domain]  Cd Length: 314  Bit Score: 35.77  E-value: 2.08e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 447177759  24 LVQFIAVAEHLNFRHAAKALGISQSSVS---ARVKALEDNlgvLLFERHARGVRLT 76
Cdd:PRK09508  27 LTVFDAVMQEQNITRAAHNLGMSQPAVSnavARLKVMFND---ELFVRYGRGIQPT 79
MarR COG1846
DNA-binding transcriptional regulator, MarR family [Transcription];
27-97 5.66e-03

DNA-binding transcriptional regulator, MarR family [Transcription];


Pssm-ID: 441451 [Multi-domain]  Cd Length: 142  Bit Score: 33.79  E-value: 5.66e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 447177759  27 FIAVAEHLNFRHAAKALGISQSSVSARVKALEDnLGVLLFERH-----ARGVRLTDAGRHFMERVTAGVDQLDHAV 97
Cdd:COG1846   46 ALAEAGGLTQSELAERLGLTKSTVSRLLDRLEE-KGLVEREPDpedrrAVLVRLTEKGRALLEEARPALEALLAEL 120
LexA COG1974
SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase) [Transcription, ...
 36-89 9.69e-03

SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase) [Transcription, Signal transduction mechanisms];


Pssm-ID: 441577 [Multi-domain]  Cd Length: 199  Bit Score: 33.35  E-value: 9.69e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 447177759  36 FRHAAKALGISQSSVSARVKALEDnLGVLLFERH-ARGVRLTDAGRH-----FMERVTAG 89
Cdd:COG1974   28 QREIAEALGLSSSAVHRHLKALEK-KGYLRRDPGkSRAIELLPASPEvvglpLLGRVAAG 86
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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