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Conserved domains on  [gi|447031763|ref|WP_001109019|]
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MULTISPECIES: Rha family transcriptional regulator [Enterobacteriaceae]

Protein Classification

Phage_pRha and ORF11CD3 domain-containing protein( domain architecture ID 10560406)

Phage_pRha and ORF11CD3 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
pRha COG3646
Phage regulatory protein Rha [Mobilome: prophages, transposons];
14-118 1.67e-37

Phage regulatory protein Rha [Mobilome: prophages, transposons];


:

Pssm-ID: 442863 [Multi-domain]  Cd Length: 211  Bit Score: 128.57  E-value: 1.67e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447031763  14 DLVFVTGNEPVTDTRKVAVAFGKEHKDVLRKTRAVVQQC-SKEFAERNFALCYENNElQNGKPQPIYRMTKDGWTMLVFG 92
Cdd:COG3646    5 ELVTIKNGEPVTSSREIAELFGKRHKNVLRDIRKLISDLeSPEFGQLNFEESTYEDS-QNGRERPEYLLTKDGFTLLVMG 83

                         90       100
                 ....*....|....*....|....*.
gi 447031763  93 FTGKAAMTFKEAYIQAFNWMAELIQQ 118
Cdd:COG3646   84 FTGKKAAEFKAAYIDRFNEMEEQLKQ 109
ORF11CD3 super family cl11180
ORF11CD3 domain; This domain was identified by Iyer and colleagues.
 123-175 1.09e-17

ORF11CD3 domain; This domain was identified by Iyer and colleagues.


The actual alignment was detected with superfamily member pfam10549:

Pssm-ID: 287514  Cd Length: 52  Bit Score: 72.87  E-value: 1.09e-17
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 447031763  123 LEAERNAVMLEYMKEKDVASMSGRLLNRWgRVKKPQLLARLDRLEQQGQIALP 175
Cdd:pfam10549   1 LMHEFNEACIELKKQKRIASLAGRGLNEW-KQVKPQLTQKVESLEEKLQPTLP 52
 
Name Accession Description Interval E-value
pRha COG3646
Phage regulatory protein Rha [Mobilome: prophages, transposons];
14-118 1.67e-37

Phage regulatory protein Rha [Mobilome: prophages, transposons];


Pssm-ID: 442863 [Multi-domain]  Cd Length: 211  Bit Score: 128.57  E-value: 1.67e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447031763  14 DLVFVTGNEPVTDTRKVAVAFGKEHKDVLRKTRAVVQQC-SKEFAERNFALCYENNElQNGKPQPIYRMTKDGWTMLVFG 92
Cdd:COG3646    5 ELVTIKNGEPVTSSREIAELFGKRHKNVLRDIRKLISDLeSPEFGQLNFEESTYEDS-QNGRERPEYLLTKDGFTLLVMG 83

                         90       100
                 ....*....|....*....|....*.
gi 447031763  93 FTGKAAMTFKEAYIQAFNWMAELIQQ 118
Cdd:COG3646   84 FTGKKAAEFKAAYIDRFNEMEEQLKQ 109
Phage_pRha pfam09669
Phage regulatory protein Rha (Phage_pRha); Members of this protein family are found in ...
 25-114 1.33e-30

Phage regulatory protein Rha (Phage_pRha); Members of this protein family are found in temperate phage and bacterial prophage regions. Members include the product of the rha gene of the lambdoid phage phi-80, a late operon gene. The presence of this gene interferes with infection of bacterial strains that lack integration host factor (IHF), which regulates the rha gene. It is suggested that Rha is a phage regulatory protein.


Pssm-ID: 462849 [Multi-domain]  Cd Length: 91  Bit Score: 106.92  E-value: 1.33e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447031763   25 TDTRKVAVAFGKEHKDVLRKTR---AVVQQCSKEFAERNFALcyENNELQNGKPQPIYRMTKDGWTMLVFGFTGKAAMTF 101
Cdd:pfam09669   1 TTSLEVAELFGKRHKNVLRDIRkliKDLEEFGEDFRELNFEE--SPYKDSQGRKRPCYLLTRDGFTLLAMGFTGKKAVEF 78

                          90
                  ....*....|...
gi 447031763  102 KEAYIQAFNWMAE 114
Cdd:pfam09669  79 KAKYIKAFNEMEE 91
phage_pRha TIGR02681
phage regulatory protein, rha family; Members of this protein family are found in temperate ...
 16-119 1.96e-27

phage regulatory protein, rha family; Members of this protein family are found in temperate phage and bacterial prophage regions. Members include the product of the rha gene of the lambdoid phage phi-80, a late operon gene. The presence of this gene interferes with infection of bacterial strains that lack integration host factor (IHF), which regulates the rha gene. It is suggested that pRha is a phage regulatory protein. [Mobile and extrachromosomal element functions, Prophage functions]


Pssm-ID: 131728  Cd Length: 108  Bit Score: 99.50  E-value: 1.96e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447031763   16 VFVTGNEPVTDTRKVAVAFGKEHKDVLRKTRAVV-QQCSKEFAERNFALCYENNElqNGKPQPIYRMTKDGWTMLVFGFT 94
Cdd:TIGR02681   5 VFTKRNQVVTDSLTMAQMFGKRHDNVIRDIKVLLiEANETEFGQLNFEETQYQDE--QNKKQPMFNLTEDGFTIVAMGYT 82

                          90       100
                  ....*....|....*....|....*
gi 447031763   95 GKAAMTFKEAYIQAFNWMAELIQQG 119
Cdd:TIGR02681  83 TPKAMKMKEKFIKEFNEMKEHLQKV 107
ORF11CD3 pfam10549
ORF11CD3 domain; This domain was identified by Iyer and colleagues.
 123-175 1.09e-17

ORF11CD3 domain; This domain was identified by Iyer and colleagues.


Pssm-ID: 287514  Cd Length: 52  Bit Score: 72.87  E-value: 1.09e-17
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 447031763  123 LEAERNAVMLEYMKEKDVASMSGRLLNRWgRVKKPQLLARLDRLEQQGQIALP 175
Cdd:pfam10549   1 LMHEFNEACIELKKQKRIASLAGRGLNEW-KQVKPQLTQKVESLEEKLQPTLP 52
 
Name Accession Description Interval E-value
pRha COG3646
Phage regulatory protein Rha [Mobilome: prophages, transposons];
14-118 1.67e-37

Phage regulatory protein Rha [Mobilome: prophages, transposons];


Pssm-ID: 442863 [Multi-domain]  Cd Length: 211  Bit Score: 128.57  E-value: 1.67e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447031763  14 DLVFVTGNEPVTDTRKVAVAFGKEHKDVLRKTRAVVQQC-SKEFAERNFALCYENNElQNGKPQPIYRMTKDGWTMLVFG 92
Cdd:COG3646    5 ELVTIKNGEPVTSSREIAELFGKRHKNVLRDIRKLISDLeSPEFGQLNFEESTYEDS-QNGRERPEYLLTKDGFTLLVMG 83

                         90       100
                 ....*....|....*....|....*.
gi 447031763  93 FTGKAAMTFKEAYIQAFNWMAELIQQ 118
Cdd:COG3646   84 FTGKKAAEFKAAYIDRFNEMEEQLKQ 109
Phage_pRha pfam09669
Phage regulatory protein Rha (Phage_pRha); Members of this protein family are found in ...
 25-114 1.33e-30

Phage regulatory protein Rha (Phage_pRha); Members of this protein family are found in temperate phage and bacterial prophage regions. Members include the product of the rha gene of the lambdoid phage phi-80, a late operon gene. The presence of this gene interferes with infection of bacterial strains that lack integration host factor (IHF), which regulates the rha gene. It is suggested that Rha is a phage regulatory protein.


Pssm-ID: 462849 [Multi-domain]  Cd Length: 91  Bit Score: 106.92  E-value: 1.33e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447031763   25 TDTRKVAVAFGKEHKDVLRKTR---AVVQQCSKEFAERNFALcyENNELQNGKPQPIYRMTKDGWTMLVFGFTGKAAMTF 101
Cdd:pfam09669   1 TTSLEVAELFGKRHKNVLRDIRkliKDLEEFGEDFRELNFEE--SPYKDSQGRKRPCYLLTRDGFTLLAMGFTGKKAVEF 78

                          90
                  ....*....|...
gi 447031763  102 KEAYIQAFNWMAE 114
Cdd:pfam09669  79 KAKYIKAFNEMEE 91
phage_pRha TIGR02681
phage regulatory protein, rha family; Members of this protein family are found in temperate ...
 16-119 1.96e-27

phage regulatory protein, rha family; Members of this protein family are found in temperate phage and bacterial prophage regions. Members include the product of the rha gene of the lambdoid phage phi-80, a late operon gene. The presence of this gene interferes with infection of bacterial strains that lack integration host factor (IHF), which regulates the rha gene. It is suggested that pRha is a phage regulatory protein. [Mobile and extrachromosomal element functions, Prophage functions]


Pssm-ID: 131728  Cd Length: 108  Bit Score: 99.50  E-value: 1.96e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447031763   16 VFVTGNEPVTDTRKVAVAFGKEHKDVLRKTRAVV-QQCSKEFAERNFALCYENNElqNGKPQPIYRMTKDGWTMLVFGFT 94
Cdd:TIGR02681   5 VFTKRNQVVTDSLTMAQMFGKRHDNVIRDIKVLLiEANETEFGQLNFEETQYQDE--QNKKQPMFNLTEDGFTIVAMGYT 82

                          90       100
                  ....*....|....*....|....*
gi 447031763   95 GKAAMTFKEAYIQAFNWMAELIQQG 119
Cdd:TIGR02681  83 TPKAMKMKEKFIKEFNEMKEHLQKV 107
ORF11CD3 pfam10549
ORF11CD3 domain; This domain was identified by Iyer and colleagues.
 123-175 1.09e-17

ORF11CD3 domain; This domain was identified by Iyer and colleagues.


Pssm-ID: 287514  Cd Length: 52  Bit Score: 72.87  E-value: 1.09e-17
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 447031763  123 LEAERNAVMLEYMKEKDVASMSGRLLNRWgRVKKPQLLARLDRLEQQGQIALP 175
Cdd:pfam10549   1 LMHEFNEACIELKKQKRIASLAGRGLNEW-KQVKPQLTQKVESLEEKLQPTLP 52
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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