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Conserved domains on  [gi|446938307|ref|WP_001015563|]
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MULTISPECIES: type II toxin-antitoxin system Phd/YefM family antitoxin [Gammaproteobacteria]

Protein Classification

type II toxin-antitoxin system Phd/YefM family antitoxin( domain architecture ID 10005482)

type II toxin-antitoxin (TA) system Phd/YefM family antitoxin is the antitoxin component of a TA module that binds to its cognate toxin and neutralizes its mRNA interferase activity; similar to Escherichia virus P1 antitoxin phd (prevent-host-death)

Gene Ontology:  GO:0003677|GO:0097351|GO:0006355|GO:0045927|GO:0110001
PubMed:  9829946|18757857|27159580

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
StbD COG2161
Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family [Defense ...
 10-84 8.19e-12

Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family [Defense mechanisms];


:

Pssm-ID: 441764  Cd Length: 83  Bit Score: 55.56  E-value: 8.19e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446938307 10 VASVSELKKNPTAVVQNAF--GEAVAILNRNNPEFYCVPAAMYERMMDLIEDQELIKLAEQV----DTDETVKVSINELR 83
Cdd:COG2161   3 TISYSEARKNLASLLDQVVedHEPVIITRRNGPAAVLISAEDYESLQETLYLLSSPANAERLleslAELEAGEVSLDELI 82


                .
gi 446938307 84 A 84
Cdd:COG2161  83 E 83
 
Name Accession Description Interval E-value
StbD COG2161
Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family [Defense ...
 10-84 8.19e-12

Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family [Defense mechanisms];


Pssm-ID: 441764  Cd Length: 83  Bit Score: 55.56  E-value: 8.19e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446938307 10 VASVSELKKNPTAVVQNAF--GEAVAILNRNNPEFYCVPAAMYERMMDLIEDQELIKLAEQV----DTDETVKVSINELR 83
Cdd:COG2161   3 TISYSEARKNLASLLDQVVedHEPVIITRRNGPAAVLISAEDYESLQETLYLLSSPANAERLleslAELEAGEVSLDELI 82


                .
gi 446938307 84 A 84
Cdd:COG2161  83 E 83
PRK09778 PRK09778
type I toxin-antitoxin system antitoxin YafN;
3-61 3.54e-06

type I toxin-antitoxin system antitoxin YafN;


Pssm-ID: 170091  Cd Length: 97  Bit Score: 41.49  E-value: 3.54e-06
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 446938307  3 HIIHSRFVASVSELKKNPTavvQNAFGEAVAILNRNNPEFYCVPAAMYERMMDLIEDQE 61
Cdd:PRK09778  2 HRILAEKSVNITELRKNPA---KYFIDQPVAVLSNNRPAGYLLSASAFEALMDMLAEQE 57
 
Name Accession Description Interval E-value
StbD COG2161
Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family [Defense ...
 10-84 8.19e-12

Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family [Defense mechanisms];


Pssm-ID: 441764  Cd Length: 83  Bit Score: 55.56  E-value: 8.19e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446938307 10 VASVSELKKNPTAVVQNAF--GEAVAILNRNNPEFYCVPAAMYERMMDLIEDQELIKLAEQV----DTDETVKVSINELR 83
Cdd:COG2161   3 TISYSEARKNLASLLDQVVedHEPVIITRRNGPAAVLISAEDYESLQETLYLLSSPANAERLleslAELEAGEVSLDELI 82


                .
gi 446938307 84 A 84
Cdd:COG2161  83 E 83
PRK09778 PRK09778
type I toxin-antitoxin system antitoxin YafN;
3-61 3.54e-06

type I toxin-antitoxin system antitoxin YafN;


Pssm-ID: 170091  Cd Length: 97  Bit Score: 41.49  E-value: 3.54e-06
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 446938307  3 HIIHSRFVASVSELKKNPTavvQNAFGEAVAILNRNNPEFYCVPAAMYERMMDLIEDQE 61
Cdd:PRK09778  2 HRILAEKSVNITELRKNPA---KYFIDQPVAVLSNNRPAGYLLSASAFEALMDMLAEQE 57
PRK02854 PRK02854
primosomal protein DnaT;
10-74 6.29e-05

primosomal protein DnaT;


Pssm-ID: 179484  Cd Length: 179  Bit Score: 39.40  E-value: 6.29e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446938307  10 VASVSELKKNPTAVVQNAFGEAVAILNRNNPEFYCVPAAMYERMMDLieDQELIKLAEQVDTDET 74
Cdd:PRK02854  10 VIGIDALVHDHQTVLAKAEGGVVAVFANNAPAFYAVTPARLAELLAL--EEKLARPGSDVALDDQ 72
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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