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Conserved domains on  [gi|446538574|ref|WP_000615920|]
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MULTISPECIES: 50S ribosomal protein L14 [Streptococcus]

Protein Classification

50S ribosomal protein L14( domain architecture ID 17564988)

50S ribosomal protein L14 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
RplN COG0093
Ribosomal protein L14 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L14 ...
1-122 1.57e-80

Ribosomal protein L14 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L14 is part of the Pathway/BioSystem: Ribosome 50S subunit


:

Pssm-ID: 439863  Cd Length: 122  Bit Score: 231.87  E-value: 1.57e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446538574   1 MIQQETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVKQATPGGAVKKGDVVKAVIVRTKTGARRPDGSYIKFD 80
Cdd:COG0093    1 MIQQGTRLKVADNSGAKEVMCIKVLGGSRRRYAGVGDIIVVSVKKATPEGKVKKGQVVKAVVVRTKKEIRRPDGSYIRFD 80
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 446538574  81 DNAAVIIRDDKTPRGTRIFGPVARELREGGYMKIVSLAPEVL 122
Cdd:COG0093   81 DNAAVLINDDGEPKGTRIFGPVARELREKGFMKIASLAPEVL 122
 
Name Accession Description Interval E-value
RplN COG0093
Ribosomal protein L14 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L14 ...
1-122 1.57e-80

Ribosomal protein L14 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L14 is part of the Pathway/BioSystem: Ribosome 50S subunit


Pssm-ID: 439863  Cd Length: 122  Bit Score: 231.87  E-value: 1.57e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446538574   1 MIQQETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVKQATPGGAVKKGDVVKAVIVRTKTGARRPDGSYIKFD 80
Cdd:COG0093    1 MIQQGTRLKVADNSGAKEVMCIKVLGGSRRRYAGVGDIIVVSVKKATPEGKVKKGQVVKAVVVRTKKEIRRPDGSYIRFD 80
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 446538574  81 DNAAVIIRDDKTPRGTRIFGPVARELREGGYMKIVSLAPEVL 122
Cdd:COG0093   81 DNAAVLINDDGEPKGTRIFGPVARELREKGFMKIASLAPEVL 122
Ribosomal_L14 pfam00238
Ribosomal protein L14p/L23e;
3-121 8.86e-74

Ribosomal protein L14p/L23e;


Pssm-ID: 425547  Cd Length: 119  Bit Score: 214.56  E-value: 8.86e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446538574    3 QQETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVKQATPGGAVKKGDVVKAVIVRTKTGARRPDGSYIKFDDN 82
Cdd:pfam00238   1 QVGTRLNVADNSGAKEVMCIKVLGGSGRRYASVGDIIVVSVKKAKPNGKVKKGDVVKAVVVRTKKEIRRPDGSYIRFDDN 80
                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 446538574   83 AAVIIRDDKTPRGTRIFGPVARELREGGYMKIVSLAPEV 121
Cdd:pfam00238  81 AAVLINDKGEPKGTRIFGPVARELREKKFPKIVSLAPEV 119
rplN_bact TIGR01067
ribosomal protein L14, bacterial/organelle; This model distinguishes bacterial and most ...
1-122 8.01e-69

ribosomal protein L14, bacterial/organelle; This model distinguishes bacterial and most organellar examples of ribosomal protein L14 from all archaeal and eukaryotic forms. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 273426  Cd Length: 122  Bit Score: 202.55  E-value: 8.01e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446538574    1 MIQQETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVKQATPGGAVKKGDVVKAVIVRTKTGARRPDGSYIKFD 80
Cdd:TIGR01067   1 MIQQQSRLNVADNSGAKKVQCIKVLGGSPRRYATVGDVIVVVVKDAIPNGKVKKGDVVKAVIVRTKKGVRRKDGSYIRFD 80
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 446538574   81 DNAAVIIRDDKTPRGTRIFGPVARELREGGYMKIVSLAPEVL 122
Cdd:TIGR01067  81 DNACVLINKNKEPRGTRIFGPVARELRDKGFMKIVSLAPEVI 122
rpl14 CHL00057
ribosomal protein L14
1-122 4.91e-65

ribosomal protein L14


Pssm-ID: 176997  Cd Length: 122  Bit Score: 192.79  E-value: 4.91e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446538574   1 MIQQETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVKQATPGGAVKKGDVVKAVIVRTKTGARRPDGSYIKFD 80
Cdd:CHL00057   1 MIQPQTYLNVADNSGARKLMCIRVLGASNRKYAHIGDVIIAVVKEAVPNMPLKRSEVVRAVIVRTCKELKRDNGMIIRFD 80
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 446538574  81 DNAAVIIRDDKTPRGTRIFGPVARELREGGYMKIVSLAPEVL 122
Cdd:CHL00057  81 DNAAVVIDQEGNPKGTRVFGPIARELREKNFTKIVSLAPEVL 122
Ribosomal_uL14 cd00337
Ribosomal protein uL14; Ribosomal protein uL14 (L14 in bacteria and mitochondria, L23 in ...
3-116 1.95e-57

Ribosomal protein uL14; Ribosomal protein uL14 (L14 in bacteria and mitochondria, L23 in eukaryotes, L38 in fungal mitochondria) is part of the large ribosomal subunit, located between the centers of activity for peptidyl transferase and GTPase. uL14 has an "all beta" fold that binds 23S rRNA. Ribosomal proteins, which are components of ribosomal subunits, are RNA-binding proteins that might have multiple extra ribosomal functions and may be involved in tumorigenesis in mammals.


Pssm-ID: 466774  Cd Length: 114  Bit Score: 173.41  E-value: 1.95e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446538574   3 QQETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVKQATPGGAVKKGDVVKAVIVRTKTGARRPDGSYIKFDDN 82
Cdd:cd00337    1 QVGTRLNVADNSGAKKVKCIKVLGKKGRRYAGVGDIIVVSVKKAKPEKKVKKGEVVKAVIVRTKKEIRRKDGSYIRFDDN 80
                         90       100       110
                 ....*....|....*....|....*....|....
gi 446538574  83 AAVIIRDDKTPRGTRIFGPVARELREGGYMKIVS 116
Cdd:cd00337   81 AVVLINKKGEPLGTRIFGPVARELRAKKFPKILS 114
 
Name Accession Description Interval E-value
RplN COG0093
Ribosomal protein L14 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L14 ...
1-122 1.57e-80

Ribosomal protein L14 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L14 is part of the Pathway/BioSystem: Ribosome 50S subunit


Pssm-ID: 439863  Cd Length: 122  Bit Score: 231.87  E-value: 1.57e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446538574   1 MIQQETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVKQATPGGAVKKGDVVKAVIVRTKTGARRPDGSYIKFD 80
Cdd:COG0093    1 MIQQGTRLKVADNSGAKEVMCIKVLGGSRRRYAGVGDIIVVSVKKATPEGKVKKGQVVKAVVVRTKKEIRRPDGSYIRFD 80
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 446538574  81 DNAAVIIRDDKTPRGTRIFGPVARELREGGYMKIVSLAPEVL 122
Cdd:COG0093   81 DNAAVLINDDGEPKGTRIFGPVARELREKGFMKIASLAPEVL 122
Ribosomal_L14 pfam00238
Ribosomal protein L14p/L23e;
3-121 8.86e-74

Ribosomal protein L14p/L23e;


Pssm-ID: 425547  Cd Length: 119  Bit Score: 214.56  E-value: 8.86e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446538574    3 QQETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVKQATPGGAVKKGDVVKAVIVRTKTGARRPDGSYIKFDDN 82
Cdd:pfam00238   1 QVGTRLNVADNSGAKEVMCIKVLGGSGRRYASVGDIIVVSVKKAKPNGKVKKGDVVKAVVVRTKKEIRRPDGSYIRFDDN 80
                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 446538574   83 AAVIIRDDKTPRGTRIFGPVARELREGGYMKIVSLAPEV 121
Cdd:pfam00238  81 AAVLINDKGEPKGTRIFGPVARELREKKFPKIVSLAPEV 119
rplN_bact TIGR01067
ribosomal protein L14, bacterial/organelle; This model distinguishes bacterial and most ...
1-122 8.01e-69

ribosomal protein L14, bacterial/organelle; This model distinguishes bacterial and most organellar examples of ribosomal protein L14 from all archaeal and eukaryotic forms. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 273426  Cd Length: 122  Bit Score: 202.55  E-value: 8.01e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446538574    1 MIQQETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVKQATPGGAVKKGDVVKAVIVRTKTGARRPDGSYIKFD 80
Cdd:TIGR01067   1 MIQQQSRLNVADNSGAKKVQCIKVLGGSPRRYATVGDVIVVVVKDAIPNGKVKKGDVVKAVIVRTKKGVRRKDGSYIRFD 80
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 446538574   81 DNAAVIIRDDKTPRGTRIFGPVARELREGGYMKIVSLAPEVL 122
Cdd:TIGR01067  81 DNACVLINKNKEPRGTRIFGPVARELRDKGFMKIVSLAPEVI 122
rpl14 CHL00057
ribosomal protein L14
1-122 4.91e-65

ribosomal protein L14


Pssm-ID: 176997  Cd Length: 122  Bit Score: 192.79  E-value: 4.91e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446538574   1 MIQQETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVKQATPGGAVKKGDVVKAVIVRTKTGARRPDGSYIKFD 80
Cdd:CHL00057   1 MIQPQTYLNVADNSGARKLMCIRVLGASNRKYAHIGDVIIAVVKEAVPNMPLKRSEVVRAVIVRTCKELKRDNGMIIRFD 80
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 446538574  81 DNAAVIIRDDKTPRGTRIFGPVARELREGGYMKIVSLAPEVL 122
Cdd:CHL00057  81 DNAAVVIDQEGNPKGTRVFGPIARELREKNFTKIVSLAPEVL 122
Ribosomal_uL14 cd00337
Ribosomal protein uL14; Ribosomal protein uL14 (L14 in bacteria and mitochondria, L23 in ...
3-116 1.95e-57

Ribosomal protein uL14; Ribosomal protein uL14 (L14 in bacteria and mitochondria, L23 in eukaryotes, L38 in fungal mitochondria) is part of the large ribosomal subunit, located between the centers of activity for peptidyl transferase and GTPase. uL14 has an "all beta" fold that binds 23S rRNA. Ribosomal proteins, which are components of ribosomal subunits, are RNA-binding proteins that might have multiple extra ribosomal functions and may be involved in tumorigenesis in mammals.


Pssm-ID: 466774  Cd Length: 114  Bit Score: 173.41  E-value: 1.95e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446538574   3 QQETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVKQATPGGAVKKGDVVKAVIVRTKTGARRPDGSYIKFDDN 82
Cdd:cd00337    1 QVGTRLNVADNSGAKKVKCIKVLGKKGRRYAGVGDIIVVSVKKAKPEKKVKKGEVVKAVIVRTKKEIRRKDGSYIRFDDN 80
                         90       100       110
                 ....*....|....*....|....*....|....
gi 446538574  83 AAVIIRDDKTPRGTRIFGPVARELREGGYMKIVS 116
Cdd:cd00337   81 AVVLINKKGEPLGTRIFGPVARELRAKKFPKILS 114
rpl14p PRK08571
50S ribosomal protein L14P; Reviewed
2-118 2.10e-32

50S ribosomal protein L14P; Reviewed


Pssm-ID: 181478  Cd Length: 132  Bit Score: 110.38  E-value: 2.10e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446538574   2 IQQETRLKVADNSGAREILTIKVLGGSGRK----FANIGDVIVASVKQATPGgavKKGDVVKAVIVRTKTGARRPDGSYI 77
Cdd:PRK08571  12 LPVGARLVCADNTGAKEVEIISVKGYKGVKrrlpKAGVGDMVVVSVKKGTPE---MRKQVLRAVVVRQRKEYRRPDGTRV 88
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 446538574  78 KFDDNAAVIIRDDKTPRGTRIFGPVARELREgGYMKIVSLA 118
Cdd:PRK08571  89 KFEDNAAVIVTPEGTPKGTEIKGPVAREAAE-RWPKIASIA 128
uL14_arch TIGR03673
50S ribosomal protein uL14, archaeal form; Part of the 50S ribosomal subunit. Forms a cluster ...
2-108 2.43e-29

50S ribosomal protein uL14, archaeal form; Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L24e, part of which may contact the 16S rRNA in 2 intersubunit bridges.


Pssm-ID: 274716  Cd Length: 131  Bit Score: 102.81  E-value: 2.43e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446538574    2 IQQETRLKVADNSGAREILTIKVLGGSGRK----FANIGDVIVASVKQATPGgavKKGDVVKAVIVRTKTGARRPDGSYI 77
Cdd:TIGR03673  11 LPVGALLVCADNTGAKEVEVISVKGYKGVKrrlpSAGVGDMVVVSVKKGTPE---MRKQVFRAVVVRQRKEYRRPDGTRV 87
                          90       100       110
                  ....*....|....*....|....*....|.
gi 446538574   78 KFDDNAAVIIRDDKTPRGTRIFGPVARELRE 108
Cdd:TIGR03673  88 KFEDNAAVIVTPDGEPKGTEIKGPVAREAAE 118
PTZ00054 PTZ00054
60S ribosomal protein L23; Provisional
11-122 3.30e-18

60S ribosomal protein L23; Provisional


Pssm-ID: 185418  Cd Length: 139  Bit Score: 74.38  E-value: 3.30e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446538574  11 ADNSGAREILTIKVLGGSGR----KFANIGDVIVASVKQATPGGAVKkgdVVKAVIVRTKTGARRPDGSYIKFDDNAAVI 86
Cdd:PTZ00054  28 ADNSGAKNLYIIAVKGIHGRlnrlPSASLGDMVLATVKKGKPELRKK---VLNAVIIRQRKAWRRKDGVFIYFEDNAGVI 104
                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 446538574  87 IRDDKTPRGTRIFGPVARELREgGYMKIVSLAPEVL 122
Cdd:PTZ00054 105 VNPKGEMKGSAITGPVAKECAD-LWPKISSAAPAIV 139
PTZ00320 PTZ00320
ribosomal protein L14; Provisional
52-118 5.33e-03

ribosomal protein L14; Provisional


Pssm-ID: 140341  Cd Length: 188  Bit Score: 35.01  E-value: 5.33e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446538574  52 VKKGDVVKAVIVRTKTGARRPDGSYIKFDDNAAVIIRDDKTPRGTRIFGPVARELREGGYMKIVSLA 118
Cdd:PTZ00320 118 VKPGNIYWVCLLSRRQTNTRMSGLQTNFDRNTCILMNDQRVPLGTRVMYCAGRHVNHKYHLKAVVLA 184
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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