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Conserved domains on  [gi|446351531|ref|WP_000429386|]
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MULTISPECIES: F0F1 ATP synthase subunit C [Gammaproteobacteria]

Protein Classification

FoF1 ATP synthase subunit c( domain architecture ID 10012848)

FoF1 ATP synthase subunit c is part of the membrane proton channel of the F-type ATPase that produces ATP from ADP in the presence of a proton gradient across the membrane

Gene Ontology:  GO:0045263|GO:0046933|GO:0008289
PubMed:  26621635

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK06876 PRK06876
F0F1 ATP synthase subunit C; Validated
 2-79 4.81e-17

F0F1 ATP synthase subunit C; Validated


:

Pssm-ID: 180739  Cd Length: 78  Bit Score: 68.04  E-value: 4.81e-17
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446351531  2 ENLNMDLLYMAAAVMMGLAAIGAAIGIGILGGKFLEGAARQPDLIPLLRTQFFIVMGLVDAIPMIAVGLGLYVMFAVA 79
Cdd:PRK06876  1 MELIMGLTAIAAAIAIGLAALGAAIGIGLLGGKFLEGAARQPELIPMLQTKMFIGAGLVDAIPIIGVGIALLFLFANP 78
 
Name Accession Description Interval E-value
PRK06876 PRK06876
F0F1 ATP synthase subunit C; Validated
 2-79 4.81e-17

F0F1 ATP synthase subunit C; Validated


Pssm-ID: 180739  Cd Length: 78  Bit Score: 68.04  E-value: 4.81e-17
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446351531  2 ENLNMDLLYMAAAVMMGLAAIGAAIGIGILGGKFLEGAARQPDLIPLLRTQFFIVMGLVDAIPMIAVGLGLYVMFAVA 79
Cdd:PRK06876  1 MELIMGLTAIAAAIAIGLAALGAAIGIGLLGGKFLEGAARQPELIPMLQTKMFIGAGLVDAIPIIGVGIALLFLFANP 78
ATP_synt_c TIGR01260
ATP synthase, F0 subunit c; This model describes the subunit c in F1/F0-ATP synthase, a ...
 34-77 2.44e-14

ATP synthase, F0 subunit c; This model describes the subunit c in F1/F0-ATP synthase, a membrane associated multisubunit complex found in bacteria and organelles of higher eukaryotes, namely, mitochondria and chloroplast. This enzyme is principally involved in the synthesis of ATP from ADP and inorganic phosphate by coupling the energy derived from the proton electrochemical gradient across the biological membrane. A brief description of this multisubunit enzyme complex: F1 and F0 represent two major clusters of subunits. The functional role of subunit c, which is the part of F0 cluster, has been delineated in-vitro reconstitution experiments. Overall experimental proof exists that demonstrate the electrochemical gradient is converted into a rotational torque that leads to ATP synthesis. [Energy metabolism, ATP-proton motive force interconversion]


Pssm-ID: 130327  Cd Length: 58  Bit Score: 60.89  E-value: 2.44e-14
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 446351531  34 KFLEGAARQPDLIPLLRTQFFIVMGLVDAIPMIAVGLGLYVMFA 77
Cdd:TIGR01260 15 KFLESAARQPELKPLLRTTMFIGMGLVDAIPMIAVVIALILLFA 58
ATP-synt_Fo_c_ATPE cd18185
F-type proton-translocating ATPase subunit c (ATPE) and similar proteins; This family includes ...
 10-73 9.23e-11

F-type proton-translocating ATPase subunit c (ATPE) and similar proteins; This family includes subunit c of F-ATP synthase (also called ATP synthase F(o) sector subunit c, F-type ATPase subunit c, or F-ATPase subunit c) and similar proteins. It is a proton-translocating subunit of the ATP synthase encoded by gene atpE.


Pssm-ID: 349425  Cd Length: 65  Bit Score: 51.71  E-value: 9.23e-11
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446351531 10 YMAAAVMMGLAAIGAAIGIGILGGKFLEGAARQPDLIPLLRTQFFIVMGLVDAIPMIAVGLGLY 73
Cdd:cd18185   1 LIAAGLAIGLAAIGAAIGDGLVGSKFIEGIARQPELRGKLRTNMFIGVGLVEAVPIIAVVIALL 64
AtpE COG0636
FoF1-type ATP synthase, membrane subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K [Energy ...
 8-78 2.89e-06

FoF1-type ATP synthase, membrane subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K [Energy production and conversion]; FoF1-type ATP synthase, membrane subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K is part of the Pathway/BioSystem: FoF1-type ATP synthase


Pssm-ID: 440401  Cd Length: 75  Bit Score: 40.49  E-value: 2.89e-06
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446351531  8 LLYMAAAVMMGLAAIGAAIGIGILGGKFLEGAARQPDLIPLLRTQFFIVMGLVDAIPMIAVGLGLYVMFAV 78
Cdd:COG0636   5 ASAIGAGLAIGLAAIGAGIGIGLAGGKALEAIARQPEAAGKLQTTMFIGAALIEALAIYALVIALILLFAN 75
 
Name Accession Description Interval E-value
PRK06876 PRK06876
F0F1 ATP synthase subunit C; Validated
 2-79 4.81e-17

F0F1 ATP synthase subunit C; Validated


Pssm-ID: 180739  Cd Length: 78  Bit Score: 68.04  E-value: 4.81e-17
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446351531  2 ENLNMDLLYMAAAVMMGLAAIGAAIGIGILGGKFLEGAARQPDLIPLLRTQFFIVMGLVDAIPMIAVGLGLYVMFAVA 79
Cdd:PRK06876  1 MELIMGLTAIAAAIAIGLAALGAAIGIGLLGGKFLEGAARQPELIPMLQTKMFIGAGLVDAIPIIGVGIALLFLFANP 78
ATP_synt_c TIGR01260
ATP synthase, F0 subunit c; This model describes the subunit c in F1/F0-ATP synthase, a ...
 34-77 2.44e-14

ATP synthase, F0 subunit c; This model describes the subunit c in F1/F0-ATP synthase, a membrane associated multisubunit complex found in bacteria and organelles of higher eukaryotes, namely, mitochondria and chloroplast. This enzyme is principally involved in the synthesis of ATP from ADP and inorganic phosphate by coupling the energy derived from the proton electrochemical gradient across the biological membrane. A brief description of this multisubunit enzyme complex: F1 and F0 represent two major clusters of subunits. The functional role of subunit c, which is the part of F0 cluster, has been delineated in-vitro reconstitution experiments. Overall experimental proof exists that demonstrate the electrochemical gradient is converted into a rotational torque that leads to ATP synthesis. [Energy metabolism, ATP-proton motive force interconversion]


Pssm-ID: 130327  Cd Length: 58  Bit Score: 60.89  E-value: 2.44e-14
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 446351531  34 KFLEGAARQPDLIPLLRTQFFIVMGLVDAIPMIAVGLGLYVMFA 77
Cdd:TIGR01260 15 KFLESAARQPELKPLLRTTMFIGMGLVDAIPMIAVVIALILLFA 58
ATP-synt_Fo_c_ATPE cd18185
F-type proton-translocating ATPase subunit c (ATPE) and similar proteins; This family includes ...
 10-73 9.23e-11

F-type proton-translocating ATPase subunit c (ATPE) and similar proteins; This family includes subunit c of F-ATP synthase (also called ATP synthase F(o) sector subunit c, F-type ATPase subunit c, or F-ATPase subunit c) and similar proteins. It is a proton-translocating subunit of the ATP synthase encoded by gene atpE.


Pssm-ID: 349425  Cd Length: 65  Bit Score: 51.71  E-value: 9.23e-11
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446351531 10 YMAAAVMMGLAAIGAAIGIGILGGKFLEGAARQPDLIPLLRTQFFIVMGLVDAIPMIAVGLGLY 73
Cdd:cd18185   1 LIAAGLAIGLAAIGAAIGDGLVGSKFIEGIARQPELRGKLRTNMFIGVGLVEAVPIIAVVIALL 64
AtpE COG0636
FoF1-type ATP synthase, membrane subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K [Energy ...
 8-78 2.89e-06

FoF1-type ATP synthase, membrane subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K [Energy production and conversion]; FoF1-type ATP synthase, membrane subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K is part of the Pathway/BioSystem: FoF1-type ATP synthase


Pssm-ID: 440401  Cd Length: 75  Bit Score: 40.49  E-value: 2.89e-06
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446351531  8 LLYMAAAVMMGLAAIGAAIGIGILGGKFLEGAARQPDLIPLLRTQFFIVMGLVDAIPMIAVGLGLYVMFAV 78
Cdd:COG0636   5 ASAIGAGLAIGLAAIGAGIGIGLAGGKALEAIARQPEAAGKLQTTMFIGAALIEALAIYALVIALILLFAN 75
PRK13464 PRK13464
F0F1 ATP synthase subunit B;
34-77 6.39e-03

F0F1 ATP synthase subunit B;


Pssm-ID: 184065  Cd Length: 101  Bit Score: 32.63  E-value: 6.39e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 446351531  34 KFLEGAARQPDLIPLLRTQFFIVMGLVDAIPMIAVGLGLYVMFA 77
Cdd:PRK13464  40 KYLEGVARQPELGGMLLGRMFIVAAFVDAFAAISIAIGFLVLYA 83
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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