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Conserved domains on  [gi|435855588|ref|YP_007316727|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Ceracris kiangsu]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475933)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-339 3.63e-93

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 280.94  E-value: 3.63e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588   1 MNNNSMKLLFLSTLMMGTILSISSNTWIGVWMGLEINLLSFIPMLANNKNMMMNESAIKYFIVQAMASTMLLFSILLIQM 80
Cdd:MTH00160   1 MMMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588  81 KNPIEwgkEIIPSMMISSSLLLKIGAAPFHFWFPEVMGSSSWINCLTLMTWQKIAPMMVLSYCIKMGMFIFLInILSIII 160
Cdd:MTH00160  81 NLMLF---NNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNNFIIIII-ILSAII 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588 161 GALGGLNQTSLRQILAYSSISHLGWMMSSLIVSENVWELYFIIYSVLSMIMVLMFKNMNLFFLNQINSSTNMKTEIKFMM 240
Cdd:MTH00160 157 GAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLL 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588 241 LLSLLSLGGLPPFLGFLPKWIVIQMLIENNLTTIMAIMVTFTTITLYYYMRISFSALILSYTENSWLINMKNNKSSFILP 320
Cdd:MTH00160 237 FLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILN 316

                        330
                 ....*....|....*....
gi 435855588 321 FLVMISTLSLMCASSLVSL 339
Cdd:MTH00160 317 FLSFISLFGLILSSLLFLL 335
 
Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-339 3.63e-93

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 280.94  E-value: 3.63e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588   1 MNNNSMKLLFLSTLMMGTILSISSNTWIGVWMGLEINLLSFIPMLANNKNMMMNESAIKYFIVQAMASTMLLFSILLIQM 80
Cdd:MTH00160   1 MMMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588  81 KNPIEwgkEIIPSMMISSSLLLKIGAAPFHFWFPEVMGSSSWINCLTLMTWQKIAPMMVLSYCIKMGMFIFLInILSIII 160
Cdd:MTH00160  81 NLMLF---NNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNNFIIIII-ILSAII 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588 161 GALGGLNQTSLRQILAYSSISHLGWMMSSLIVSENVWELYFIIYSVLSMIMVLMFKNMNLFFLNQINSSTNMKTEIKFMM 240
Cdd:MTH00160 157 GAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLL 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588 241 LLSLLSLGGLPPFLGFLPKWIVIQMLIENNLTTIMAIMVTFTTITLYYYMRISFSALILSYTENSWLINMKNNKSSFILP 320
Cdd:MTH00160 237 FLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILN 316

                        330
                 ....*....|....*....
gi 435855588 321 FLVMISTLSLMCASSLVSL 339
Cdd:MTH00160 317 FLSFISLFGLILSSLLFLL 335
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 24-280 1.00e-21

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 93.15  E-value: 1.00e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588   24 SNTWIGVWMGLEINLLSFIPMLA-NNKNMMMNESAIKYFIVQAMASTMLLFSILLI--------------QMKNPIEWGK 88
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGyWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMynytgtlsfdelskALTGGLNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588   89 EIIPSMMISSSLLLKIGAAPFHFWFPEV-MGSSSWINCLTLMTWQKIAPMMVL-------SYCIKMGMFIFLINILSIII 160
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAyEGAPTPVSALLAATLVKAGGYGLIrrsllylPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588  161 GALGGLNQTSLRQILAYSSISHLGWMMSSLIV----SENVWELYFIIYSVLSMIMVLMFKNMNL-----FFLNQINSSTN 231
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAgtiyGIQAAIFHLLTHGLFSAGLFLCAGSVIYrrvhtRNIRDYGGLAK 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 435855588  232 MKTEIKFMMLLSLLSLGGLPPFLGFLPKWIVIQMLIENNLTTIMAIMVT 280
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVV 289
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 8-292 1.22e-18

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 86.32  E-value: 1.22e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588   8 LLFLSTLmmGTILSISSNTWIGVWMGLEINLLSFIPMLA-NNKNMMMNESAIKYFIVQAMASTMLLF----------SIL 76
Cdd:COG1007  107 LLLFATL--GMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgisllygatgSLN 184

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588  77 LIQMKNPIEWGKEIIPSMMISSSLLL-----KIGAAPFHFWFPEVMGSSSWINCLTLMTWQKIAPMMVL---------SY 142
Cdd:COG1007  185 LAGIAAALAAGGANSPLLLLGLVLVLaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALlrllveafpGL 264

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588 143 CIKMGMFIFLINILSIIIGALGGLNQTSLRQILAYSSISHLGWMMSSLIV-SENVWE---LYFIIYSVlsmimvlmfknM 218
Cdd:COG1007  265 AADWQLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAgTPLGVSaalFYLLAYLF-----------M 333

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588 219 NL---FFLNQINSSTNMKTEIK-----FMMLLSLLSLGGLPPF--------LGFLPKWIVIQMLIENNLTTIMAIMVTFT 282
Cdd:COG1007  334 NLgafAVILLLSRKGGEAEEIEdlaglARRSPLLALAMTIFLLslagipptAGFFGKFYVFSAAVEAGLYWLAVIAVLNS 413

                        330
                 ....*....|
gi 435855588 283 TITLYYYMRI 292
Cdd:COG1007  414 VISAYYYLRV 423
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 17-331 5.18e-16

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 78.45  E-value: 5.18e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588   17 GTILSISSNTWIGVWMGLEI-NLLSFIPMLANNKNMMMNESAIKYFIVQAMASTMLLF---------------SILLIQM 80
Cdd:TIGR01770 114 GIFLLVSSNDLLSIYLGLELqSLCFYVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLFgisliygftgslnfeDLLLFLS 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588   81 KNPIEWGKEIIPSMMISSSLLLKIGAAPFHFWFPEVMGSSSWINCLTLMTWQKIA---PMMVLSYCIKMGM------FIF 151
Cdd:TIGR01770 194 NGMLNISLLLLGIVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAifaVFLRLFLYILFGFseawqiFLA 273

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588  152 LINILSIIIGALGGLNQTSLRQILAYSSISHLGW-MMSSLIVSENVWE---LYFIIYSVLSMIMVLMFKNMNLFFLNQIN 227
Cdd:TIGR01770 274 IIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYiLIGLLAGTLEGIKavlFYIFIYALMSLGAFGVLSLLRSYKDEWIE 353

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588  228 SSTNMKTEIKFMMLLSLLSLGGLP------PFLGFLPKWIVIQMLIENNLTTIMAIMVTFTTITLYYYMRIsfSALILSY 301
Cdd:TIGR01770 354 YISDFAGLFKTNPILAILILIFMFslagipPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRV--VKVMYFD 431

                         330       340       350
                  ....*....|....*....|....*....|.
gi 435855588  302 TENSWLINMKNNKS-SFILPFLVMISTLSLM 331
Cdd:TIGR01770 432 KPERRIPSNPQSKAqSLLLSISALFILFLGL 462
 
Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-339 3.63e-93

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 280.94  E-value: 3.63e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588   1 MNNNSMKLLFLSTLMMGTILSISSNTWIGVWMGLEINLLSFIPMLANNKNMMMNESAIKYFIVQAMASTMLLFSILLIQM 80
Cdd:MTH00160   1 MMMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588  81 KNPIEwgkEIIPSMMISSSLLLKIGAAPFHFWFPEVMGSSSWINCLTLMTWQKIAPMMVLSYCIKMGMFIFLInILSIII 160
Cdd:MTH00160  81 NLMLF---NNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNNFIIIII-ILSAII 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588 161 GALGGLNQTSLRQILAYSSISHLGWMMSSLIVSENVWELYFIIYSVLSMIMVLMFKNMNLFFLNQINSSTNMKTEIKFMM 240
Cdd:MTH00160 157 GAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLL 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588 241 LLSLLSLGGLPPFLGFLPKWIVIQMLIENNLTTIMAIMVTFTTITLYYYMRISFSALILSYTENSWLINMKNNKSSFILP 320
Cdd:MTH00160 237 FLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILN 316

                        330
                 ....*....|....*....
gi 435855588 321 FLVMISTLSLMCASSLVSL 339
Cdd:MTH00160 317 FLSFISLFGLILSSLLFLL 335
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 7-330 2.57e-55

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 183.87  E-value: 2.57e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588   7 KLLFLSTLMMGTILSISSNTWIGVWMGLEINLLSFIPMLANNKNMMMNESAIKYFIVQAMASTMLLFSILL--------- 77
Cdd:MTH00112   6 KLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTnawntgqwd 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588  78 -IQMKNPIewgkeiiPSMMISSSLLLKIGAAPFHFWFPEVMGSSSWINCLTLMTWQKIAPMMVL---SYCIKMgMFIFLI 153
Cdd:MTH00112  86 iTQLTNPT-------SCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLlmtSNSLNP-TLLLTL 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588 154 NILSIIIGALGGLNQTSLRQILAYSSISHLGWMMSSLIVSENVWELYFIIYSVLSMIMVLMFKNMNLFFLNQINSSTNMK 233
Cdd:MTH00112 158 AILSTLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKS 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588 234 TEIKFMMLLSLLSLGGLPPFLGFLPKWIVIQMLIENNLTTIMAIMVTFTTITLYYYMRISFSALILSyTENSWLINMK-- 311
Cdd:MTH00112 238 PTLNTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITL-PPNTTNMMMKwr 316

                        330       340
                 ....*....|....*....|
gi 435855588 312 -NNKSSFILPFLVMISTLSL 330
Cdd:MTH00112 317 tKPKKNTLTATLTTLSTLLL 336
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 8-330 5.96e-55

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 183.12  E-value: 5.96e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588   8 LLFLSTLMMGTILSISSNTWIGVWMGLEINLLSFIPMLANNKNMMMNESAIKYFIVQAMASTMLLFSIL----------L 77
Cdd:MTH00105   7 IIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIinlmysgqwtI 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588  78 IQMKNPiewgkeiIPSMMISSSLLLKIGAAPFHFWFPEVMGSSSWINCLTLMTWQKIAPMMVL---SYCIKMGMfIFLIN 154
Cdd:MTH00105  87 TKLTNP-------TASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILyqiSPSINPNL-LLTLA 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588 155 ILSIIIGALGGLNQTSLRQILAYSSISHLGWMMSSLIVSENVWELYFIIYSVLSMIMVLMFKNMNLFFLNQINSSTNMKT 234
Cdd:MTH00105 159 ILSILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTP 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588 235 EIKFMMLLSLLSLGGLPPFLGFLPKWIVIQMLIENNLTTIMAIMVTFTTITLYYYMRISFS-ALILSYTENswliNMK-- 311
Cdd:MTH00105 239 LMTSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYStSLTMFPSTN----NMKmk 314

                        330       340
                 ....*....|....*....|...
gi 435855588 312 ----NNKSSFILPFLVMISTLSL 330
Cdd:MTH00105 315 wqfeNTKPMTLLPTLIILSTMLL 337
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 10-340 4.90e-53

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 177.81  E-value: 4.90e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588  10 FLSTLMMGTILSISSNTWIGVWMGLEINLLSFIPMLANNKNMMMNESAIKYFIVQAMASTMLLFSILL----------IQ 79
Cdd:MTH00070   9 LLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTInawftgewtiMN 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588  80 MKNPIewgkeiiPSMMISSSLLLKIGAAPFHFWFPEVMGSSSWINCLTLMTWQKIAPMMVL---SYCIKMGMFIFLiNIL 156
Cdd:MTH00070  89 MQTPL-------PTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLiqiSHLLNSNLLIIM-GLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588 157 SIIIGALGGLNQTSLRQILAYSSISHLGWMMSSLIVSENVWELYFIIYSVLSMIMVLMFKNMNLFFLNQInSSTNMKTEI 236
Cdd:MTH00070 161 STLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKL-SSSWSKNPT 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588 237 KFMMLLSLLSLGGLPPFL-GFLPKWIVIQMLIENNLTTIMAIMVTFTTITLYYYMRISFS-ALILS-YTENSWLINMKNN 313
Cdd:MTH00070 240 LTSMMMLTLLSLGGLPPTtGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAmSLTTSpNTSNSKLYWRFKN 319

                        330       340
                 ....*....|....*....|....*..
gi 435855588 314 KSSFILPFLVMISTLSLMCASSLVSLY 340
Cdd:MTH00070 320 KTNNLLSLTIILSLMLLPITPTILNLF 346
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 3-340 8.48e-53

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 177.43  E-value: 8.48e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588   3 NNSMKLLFLSTLMMGTILSISSNTWIGVWMGLEINLLSFIPMLANNKNMMMNESAIKYFIVQAMASTMLLFSILlIQMKN 82
Cdd:MTH00041   2 NRNVLIFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGAL-IQAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588  83 PIEWG----KEIIPSMMISSSLLLKIGAAPFHFWFPEVMGSSSWINCLTLMTWQKIAPMMVLSYCIKMGMF--IFLINIL 156
Cdd:MTH00041  81 SGSWSingpLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSniLILCGIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588 157 SIIIGALGGLNQTSLRQILAYSSISHLGWMMSSLIVSENVWELYFIIYSVLSMIMVLMFKNMNLFFLNQINSSTNMKTEI 236
Cdd:MTH00041 161 SVLVGGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPIS 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588 237 KFMMLLSLLSLGGLPPFLGFLPKWIVIQMLIENNLTTIMAIMVTFTTITLYYYMRISFSALILSYTENS-----WLINMK 311
Cdd:MTH00041 241 AFLFILSILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHSislfsWRNSGN 320

                        330       340
                 ....*....|....*....|....*....
gi 435855588 312 NNKSSFILPFLVMISTLSLMCASSLVSLY 340
Cdd:MTH00041 321 ITVYGVILSILSSISILGLLLIPLFLSFL 349
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 5-322 5.94e-50

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 169.30  E-value: 5.94e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588   5 SMKLLFLSTLMMGTILSISSNTWIGVWMGLEINLLSFIPMLANNKNMMMNESAIKYFIVQAMASTMLLFSILLIQMKNPI 84
Cdd:MTH00144   4 PSNLLFLFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFS 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588  85 EWGkeiipSMMISSSLLLKIGAAPFHFWFPEVMGSSSWINCLTLMTWQKIAPMMVLSYCI---KMGMFIFLINILSIIIG 161
Cdd:MTH00144  84 WFS-----MSLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLdlyWLAYLLCVISVLSALVG 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588 162 ALGGLNQTSLRQILAYSSISHLGWMMSSLIVSENVWELYFIIYSVLSMIMVLMFKNMNLFFLNQINSSTNMKTEiKFMML 241
Cdd:MTH00144 159 SIGGLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDLGSLKPSYKT-GLSII 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588 242 LSLLSLGGLPPFLGFLPKWIVIQMLIENNLTTIMAIMVTFTTITLYYYMRISFSALILSYTENSWLINMKNNKSSFILPF 321
Cdd:MTH00144 238 SLLLSLGGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKVLNSSIISLNL 317


                 .
gi 435855588 322 L 322
Cdd:MTH00144 318 L 318
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 9-331 8.28e-49

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 166.39  E-value: 8.28e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588   9 LFLSTLMMGTILSISSNTWIGVWMGLEINLLSFIPMLANNKNMMMNESAIKYFIVQAMASTMLLFSILLIQMKNPIEWGk 88
Cdd:MTH00197   2 LFLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLSFSNLYLSLL- 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588  89 eiiPSMMISSSLLLKIGAAPFHFWFPEVMGSSSWINCLTLMTWQKIAPMMVLSYCIKMGMFIFLINILSIIIGALGGLNQ 168
Cdd:MTH00197  81 ---SVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFNSSSFMGLLICSVLSSLIGGIGGMNQ 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588 169 TSLRQILAYSSISHLGWMMSSLIVSENVWELYFIIYSVLSMIMVLMFKNMNLFFLNQINSSTNMKTEIKFMMLLSLLSLG 248
Cdd:MTH00197 158 SNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFLSLG 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588 249 GLPPFLGFLPKWIVIQMLIENNLTTIMAIMVTFTTITLYYYMRISFSALILSYTENSWLINMKNNkssFILPFLVMISTL 328
Cdd:MTH00197 238 GLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKSLILSNWMINFLMKINLL---YSGLFILLMMML 314


                 ...
gi 435855588 329 SLM 331
Cdd:MTH00197 315 PLL 317
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 6-339 2.54e-47

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 163.22  E-value: 2.54e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588   6 MKLLFLSTLMMGTILSISSNTWIGVWMGLEINLLSFIPMLANNKNMMMNESAIKYFIVQAMASTMLLFSILLIQM---KN 82
Cdd:MTH00200   5 ILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWtsgQW 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588  83 PIEWGKEIIPSMMISSSLLLKIGAAPFHFWFPEVMGSSSWINCLTLMTWQKIAPMMVLS--YCIKMGMFIFLINILSIII 160
Cdd:MTH00200  85 GISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIqlAPALNSNILLLLGLLSVLV 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588 161 GALGGLNQTSLRQILAYSSISHLGWMMSSLIVSENVWELYFIIYSVLSMIMVLMFKNMNLFFLNQINSSTNMKTEIKFMM 240
Cdd:MTH00200 165 GGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPILSMLL 244

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588 241 LLSLLSLGGLPPFLGFLPKWIVIQMLIENNLTTIMAIMVTFTTITLYYYMRISFSALILS--YTENSWLINMKNNKSSFI 318
Cdd:MTH00200 245 GLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLspNQINMMSSWRTKSNSNLL 324

                        330       340
                 ....*....|....*....|.
gi 435855588 319 LPFLVMISTLSLMCASSLVSL 339
Cdd:MTH00200 325 VGLLLLLSILGLPLTPQLLFL 345
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 9-295 8.54e-47

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 161.51  E-value: 8.54e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588   9 LFLSTLMMGTILSISSNTWIGVWMGLEINLLSFIPMLANNKNMMMNESAIKYFIVQAMASTMLLFSIL----------LI 78
Cdd:MTH00135   8 ILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTtnawltgqwdIQ 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588  79 QMKNPIewgkeiiPSMMISSSLLLKIGAAPFHFWFPEVMGSSSWINCLTLMTWQKIAPMmVLSYCIKMGMFIFLI--NIL 156
Cdd:MTH00135  88 QMSHPL-------PTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPF-ALILQIAPTNPTLLItlGLT 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588 157 SIIIGALGGLNQTSLRQILAYSSISHLGWMMSSLIVSENVWELYFIIYSVLSMIMVLMFKNmnlfflnqiNSSTNMKTEI 236
Cdd:MTH00135 160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKL---------NSSTKINTLA 230

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 435855588 237 KFMMLLSLLSLGGLPPFL---------GFLPKWIVIQMLIENNLTTIMAIMVTFTTITLYYYMRISFS 295
Cdd:MTH00135 231 TSWTKAPALTALTPLILLslgglppltGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYA 298
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 8-330 1.48e-44

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 155.32  E-value: 1.48e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588   8 LLFLSTLMMGTILSISSNTWIGVWMGLEINLLSFIPMLANNKNMMMNESAIKYFIVQAMASTMLLFSILLIQMKNPIewg 87
Cdd:MTH00011   9 FLFSSTMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTMMWSFPSL--- 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588  88 KEIIPSMMISSSLLLKIGAAPFHFWFPEVMGSSSWINCLTLMTWQKIAPMMVLSYC--IKMGMFIFLINILSIIIGALGG 165
Cdd:MTH00011  86 LKNITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFtsHNILPMMTSMAAMSALAGGLGG 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588 166 LNQTSLRQILAYSSISHLGWMMSSLIVSENVWELYFIIYSVLSMIMVLMFKNMNLFFLNQINSSTNMKTEIKFMMLLSLL 245
Cdd:MTH00011 166 MNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLFIMLL 245

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588 246 SLGGLPPFLGFLPKWIVIQMLIENNLTTIMAIMVTFTTITLYYYMRISFSALILSYTenswLINMKNNKSSFILPFLVMI 325
Cdd:MTH00011 246 SLGGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFNFMYLSPT----FSSLKSAPYEPKTKILISM 321


                 ....*
gi 435855588 326 STLSL 330
Cdd:MTH00011 322 CTLSL 326
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 24-280 1.00e-21

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 93.15  E-value: 1.00e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588   24 SNTWIGVWMGLEINLLSFIPMLA-NNKNMMMNESAIKYFIVQAMASTMLLFSILLI--------------QMKNPIEWGK 88
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGyWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMynytgtlsfdelskALTGGLNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588   89 EIIPSMMISSSLLLKIGAAPFHFWFPEV-MGSSSWINCLTLMTWQKIAPMMVL-------SYCIKMGMFIFLINILSIII 160
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAyEGAPTPVSALLAATLVKAGGYGLIrrsllylPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588  161 GALGGLNQTSLRQILAYSSISHLGWMMSSLIV----SENVWELYFIIYSVLSMIMVLMFKNMNL-----FFLNQINSSTN 231
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAgtiyGIQAAIFHLLTHGLFSAGLFLCAGSVIYrrvhtRNIRDYGGLAK 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 435855588  232 MKTEIKFMMLLSLLSLGGLPPFLGFLPKWIVIQMLIENNLTTIMAIMVT 280
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVV 289
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 16-292 1.91e-19

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 87.78  E-value: 1.91e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588  16 MGTILSISSNTWIGVWMGLEINLLSFIPMLANNKNMMMN-ESAIKYFIVQAMASTMLLF-----------------SILL 77
Cdd:MTH00196   4 LGILCLISSSNWLSVYLAIELQTLSLFILIAQNRGSGYSaEAGLKYFVLGALSSGLFLFgcallcgttgglhlsyiNLVL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588  78 IQMKNPIEWGKEIiPSMMISSSLLLKIGAAPFHFWFPEVMGSSSWINCLTLMTWQKIAPMMVLSYCIKMGMFIFLINILS 157
Cdd:MTH00196  84 NSGQSFSSVSVPI-GYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNVNILLIGGLFS 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588 158 IIIGALGGLNQTSLRQILAYSSISHLGWMMSSL----IVSENVWELYFIIYSVLSM--IMVLMFKNMNLFFLNQINSSTN 231
Cdd:MTH00196 163 LFVGAIGALNQTKIKRLLAYSGIGHMGFVLWGIeigsFESIQASLVYLFIYIIMSIcvFSIILALNVYKNLIIEFSGLSR 242

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 435855588 232 MKTEIKFMMLLSLLSLGGLPPFLGFLPKWIVIQMLIENNLTTIMAIMVTFTTITLYYYMRI 292
Cdd:MTH00196 243 RLPILAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRI 303
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
8-292 1.18e-18

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 86.41  E-value: 1.18e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588   8 LLFLSTLmmGTILSISSNTWIGVWMGLEINLLSFIPMLA-NNKNMMMNESAIKYFIVQAMASTMLLFSILLI-------- 78
Cdd:PRK05777 108 LVLFALL--GMMVMVSANDLLTLFLGLELLSLPLYALAAlRRDRRRSLEAAIKYFVLGALASGFLLYGMSLLygatgsls 185

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588  79 --QMKNPIEWGKEIIPSM-----MISSSLLLKIGAAPFHFWFPEVMGSSSWINCLTLMTWQKIAPMMVL---------SY 142
Cdd:PRK05777 186 faGIAKALADGSGNSLLLlfglvFLLVGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAVLlrllvvafgGL 265

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588 143 CIKMGMFIFLINILSIIIGALGGLNQTSLRQILAYSSISHLGWMMSSLIVS-----ENVWeLYFIIYSVLSM---IMVLM 214
Cdd:PRK05777 266 SEDWQQVLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLAAGtaegySAVL-FYLLAYLFMTLgafGVISL 344

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588 215 FKNM-----NLFFLNQINSSTNMKTeikFMMLLSLLSLGGLPPFLGFLPKWIVIQMLIENNLTTIMAIMVTFTTITLYYY 289
Cdd:PRK05777 345 LRRKggeaeSISDFAGLSKRSPLLA---AVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYY 421


                 ...
gi 435855588 290 MRI 292
Cdd:PRK05777 422 LRV 424
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 8-292 1.22e-18

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 86.32  E-value: 1.22e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588   8 LLFLSTLmmGTILSISSNTWIGVWMGLEINLLSFIPMLA-NNKNMMMNESAIKYFIVQAMASTMLLF----------SIL 76
Cdd:COG1007  107 LLLFATL--GMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgisllygatgSLN 184

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588  77 LIQMKNPIEWGKEIIPSMMISSSLLL-----KIGAAPFHFWFPEVMGSSSWINCLTLMTWQKIAPMMVL---------SY 142
Cdd:COG1007  185 LAGIAAALAAGGANSPLLLLGLVLVLaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALlrllveafpGL 264

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588 143 CIKMGMFIFLINILSIIIGALGGLNQTSLRQILAYSSISHLGWMMSSLIV-SENVWE---LYFIIYSVlsmimvlmfknM 218
Cdd:COG1007  265 AADWQLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAgTPLGVSaalFYLLAYLF-----------M 333

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588 219 NL---FFLNQINSSTNMKTEIK-----FMMLLSLLSLGGLPPF--------LGFLPKWIVIQMLIENNLTTIMAIMVTFT 282
Cdd:COG1007  334 NLgafAVILLLSRKGGEAEEIEdlaglARRSPLLALAMTIFLLslagipptAGFFGKFYVFSAAVEAGLYWLAVIAVLNS 413

                        330
                 ....*....|
gi 435855588 283 TITLYYYMRI 292
Cdd:COG1007  414 VISAYYYLRV 423
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 16-292 7.25e-18

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 83.91  E-value: 7.25e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588  16 MGTILSISSNTWIGVWMGLEINLLSFIPMLANNKNMMMN-ESAIKYFIVQAMASTMLLFSILL---------IQMKNPI- 84
Cdd:MTH00199 108 LGSLLLVSSINWLSIYLAIELQTLTLFILVALKRDSAYStEAGLKYFVLGAVSSGLFLFGCALlygltgetsIQGINSIl 187

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588  85 --EWGKeiipsMMISSSLLLKIGAAPFHFWFPEVMGSSSWINCLTLMTWQKIAPMMVLSYCIKMGMFIFLINILSIIIGA 162
Cdd:MTH00199 188 tgDVGK-----ILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNVVLICAVLSIIYGA 262

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588 163 LGGLNQTSLRQILAYSSISHLGWMMSSLIVSENVWELYFIIYSVLSMIM------VLMFKNMNLFFLNQINSSTNMKTEI 236
Cdd:MTH00199 263 IGALNQTKIKRLLAYSGIGHMGFILFGVAIGSFESIQASLIYMIIYVIMsicsfsIILSLKLTKGLIVEVSGLSRKNPVI 342

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 435855588 237 KFMMLLSLLSLGGLPPFLGFLPKWIVIQMLIENNLTTIMAIMVTFTTITLYYYMRI 292
Cdd:MTH00199 343 ALTLALTFLSIAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRV 398
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 17-331 5.18e-16

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 78.45  E-value: 5.18e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588   17 GTILSISSNTWIGVWMGLEI-NLLSFIPMLANNKNMMMNESAIKYFIVQAMASTMLLF---------------SILLIQM 80
Cdd:TIGR01770 114 GIFLLVSSNDLLSIYLGLELqSLCFYVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLFgisliygftgslnfeDLLLFLS 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588   81 KNPIEWGKEIIPSMMISSSLLLKIGAAPFHFWFPEVMGSSSWINCLTLMTWQKIA---PMMVLSYCIKMGM------FIF 151
Cdd:TIGR01770 194 NGMLNISLLLLGIVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAifaVFLRLFLYILFGFseawqiFLA 273

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588  152 LINILSIIIGALGGLNQTSLRQILAYSSISHLGW-MMSSLIVSENVWE---LYFIIYSVLSMIMVLMFKNMNLFFLNQIN 227
Cdd:TIGR01770 274 IIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYiLIGLLAGTLEGIKavlFYIFIYALMSLGAFGVLSLLRSYKDEWIE 353

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588  228 SSTNMKTEIKFMMLLSLLSLGGLP------PFLGFLPKWIVIQMLIENNLTTIMAIMVTFTTITLYYYMRIsfSALILSY 301
Cdd:TIGR01770 354 YISDFAGLFKTNPILAILILIFMFslagipPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRV--VKVMYFD 431

                         330       340       350
                  ....*....|....*....|....*....|.
gi 435855588  302 TENSWLINMKNNKS-SFILPFLVMISTLSLM 331
Cdd:TIGR01770 432 KPERRIPSNPQSKAqSLLLSISALFILFLGL 462
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 16-187 9.77e-12

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 66.04  E-value: 9.77e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588  16 MGTILSISSNTWIGVWMGLEINLLSFIPM---------LANNKNMMMNESAIKYFIVQAMASTMLLF------------- 73
Cdd:MTH00198 199 LGGLLLIESANWLTIYLALEFQTLALFILagegsqpgsHFPSPGNTPPESGLKYWILGAMSSGFYLFgcalyfgftgneg 278

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588  74 ---SILLIQMKNP-IEWGKEIIPSMMISSSLLLKIGAAPFHFWFPEVMGSSSWINCLTLMTWQKIAPMMVLSYCIKMGMF 149
Cdd:MTH00198 279 mlgTILSATLETTnIELRQGSLGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILLTSLVITSKL 358

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 435855588 150 IFLINILSIIIGALGGLNQTSLRQILAYSSISHLGWMM 187
Cdd:MTH00198 359 LLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFIL 396
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 10-187 2.34e-07

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 52.07  E-value: 2.34e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588  10 FLSTLMMGTILSISSNTWIGVWMGLEINLLSFIPMLANNKNMMMNESAIKYFIVQAMASTMLLFSILLIQ-------MKN 82
Cdd:COG0651  112 LFLLLLAGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYgatgtlnMAD 191

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588  83 PIEWGKEIIPSMMISSSLLL------KIGAAPFHFWFPEVMGS-SSWINCL--TLMTwqKIAPMMVL---------SYCI 144
Cdd:COG0651  192 LAARLAELDPGLLLAAFALLlvgfgiKAALFPLHFWLPDAYPAaPSPVSALlsGLLT--KVGVYAILrvltllfgaDPAL 269

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 435855588 145 KMGMFIFLINILSIIIGALGGLNQTSLRQILAYSSISHLGWMM 187
Cdd:COG0651  270 FLGTLLLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYIL 312
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 55-187 4.98e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 48.17  E-value: 4.98e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588  55 ESAIKYFIVQAMASTMLLFSI-LLIQMKNPIEWGK------------EIIPSMMISSSLLLKIGAAPFHFWFPEVMGSS- 120
Cdd:PRK08376 172 EAGIKYMFVGSLASSMVLLGIaLLYGQYGTLNMAYlavkmsenptvvAKIALALFIAGLAMKSGAVPVHMWLPDAYPAAp 251

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 435855588 121 SWINCLTLMTWQ-KIAPMMVLSYCI--------KMGMFIFLINILSIIIGALGGLNQTSLRQILAYSSISHLGWMM 187
Cdd:PRK08376 252 SSISAMLLVIKQaGLYALARVLFSIygpainlaTVGWVIIILGCLTMFVGVAMAVVQKDVKRLLAYHSVSQIGYML 327
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 34-187 1.47e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 46.41  E-value: 1.47e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588  34 LEINLLSFIPMLANNKNMMMNESAIKYFIVQAMASTMLLFSILLIQMK-----------NPIEWGKEIIPSMMISSSLLL 102
Cdd:PRK08375 135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGVGLLYGVtgtlnmadlagALAENPTVVTAFGFVLLALAL 214

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588 103 KIGAAPFHFWFPEVM-GSSSWINCLTLMTWQKIAPMMVL---------SYCIKMGMFIFL--INILSIIIGALGGLNQTS 170
Cdd:PRK08375 215 KAAVFPLHTWLPRAYpAAPPVVTALLSGLVTKVAVYALIriyftvfggDFRFALGLGWLLavLALLSMLVGSLAALGQDD 294

                        170
                 ....*....|....*..
gi 435855588 171 LRQILAYSSISHLGWMM 187
Cdd:PRK08375 295 VKRVLAYSTVSQMGYIL 311
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
54-192 1.64e-05

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 46.58  E-value: 1.64e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588  54 NESAIKYFIVQAMASTMLLFSI-LLIQMKNPIEWGKEIIPSMMISSSLLL-------------KIGAAPFHFWFPEVMGS 119
Cdd:PRK02504 160 NEAALKYLLIGAASSAIFLYGSsLLYGLSGGSTQLSAIALALITSPSLGLalalvfviagiafKISAVPFHQWTPDVYEG 239

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588 120 SSWINCLTLMTWQKIA----PMMVLSYCI----KMGMFIF-LINILSIIIGALGGLNQTSLRQILAYSSISHLGWMMSSL 190
Cdd:PRK02504 240 SPTPVVAFLSVGSKAAgfalAIRLLVTAFpsfdEQWKLLFtALAILSMVLGNVVALAQTSMKRMLAYSSIGQAGFVMIGL 319


                 ..
gi 435855588 191 IV 192
Cdd:PRK02504 320 VA 321
ndhB CHL00049
NADH dehydrogenase subunit 2
 8-194 1.82e-05

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 46.15  E-value: 1.82e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588   8 LLFLSTLMMGTILSISSNTWIGVWMGLE-INLLSFIPMLANNKNMMMNESAIKYFIVQAMASTMLLF------------- 73
Cdd:CHL00049 114 LLFVLTATLGGMFLCGANDLITIFVALEcLSLCSYLLSGYTKKDVRSNEATMKYLLMGGASSSILVYgfswlyglsggei 193

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588  74 -------SILLIQMKNPIewGKEIIPsMMISSSLLLKIGAAPFHFWFPEVMGSSSWINCLTLMTWQKIAPMMvLSYCIKM 146
Cdd:CHL00049 194 elqeivnGLINTQMYNSP--GISIAL-IFITVGIGFKLSLAPFHQWTPDVYEGSPTPVVAFLSVTSKVAASA-LATRIFD 269

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 435855588 147 GMFIFLIN----------ILSIIIGALGGLNQTSLRQILAYSSISHLGWMMSSLIVSE 194
Cdd:CHL00049 270 IPFYFSSNewhllleilaILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGD 327
PRK12650 PRK12650
DUF4040 family protein;
94-192 1.27e-04

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 43.88  E-value: 1.27e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588  94 MMISSSLLLKIGAAPFHFWFPEVMGSSSWINcltlmTWQKIAPMmvlsycIKMGMFIFLI-----------NILSIIIG- 161
Cdd:PRK12650 212 VLIAVAAFTKSAQFPFHFWLPEAMAAITPVS-----AFLHAAAV------VKAGIYLLLRfspvfhdvavwNWLLIIVGm 280

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 435855588 162 ------ALGGLNQTSLRQILAYSSISHLGWMMSSLIV 192
Cdd:PRK12650 281 italmgAVFAVQKTDLKKLTAYSTVSQLGWIVATIGV 317
ND2 MTH00091
NADH dehydrogenase subunit 2; Provisional
 14-224 2.86e-04

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177154  Cd Length: 273  Bit Score: 41.78  E-value: 2.86e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588  14 LMMGTILSISSNTWIGVWMGLEINLLSFIPMLANNKNMMMNesaikYFIVQAMASTMLLFSILLIQMknpiewgkeiips 93
Cdd:MTH00091   3 LSLLNFMSLNIFVWWSVFLLMTLLFVFLNKGMGSYSSLFNY-----FVLQESLGLLFLLFSFGYFQF------------- 64

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588  94 mmisSSLLLKIGAAPFHFWFPEVMGSSSWINCLTLMTWQKIAPMMVLSYCIKMGMFIFLinILSIIIGALGGLNQTSLRQ 173
Cdd:MTH00091  65 ----LILMMKIGVAPFHFWIFSVTNGLFGWNLMWFLTFQKLPFLLVLLQFFSKNFFFLL--LFGLLICFFQMFLLKSYKN 138

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 435855588 174 ILAYSSISHLGWMMSSLIVSENVWELYFIIYSVLSMIMVLMFKNMNLFFLN 224
Cdd:MTH00091 139 LLILSSTESFNWLILSFFFSFFNVFFLFFYYFLLMLFLIPKFNNVNKLNFV 189
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 8-187 5.54e-03

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 38.38  E-value: 5.54e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588    8 LLFLSTLMMGTILSISSNTWIGVWMGLEINLLSFIPMLANNKNMMmneSAIKYFIVQAMASTMLLFSILLIQMKNPIEWG 87
Cdd:TIGR01972 112 LLLLEAGVIGVFLALDLFLFYVFWEAMLIPMYLLIGVWGGPNRIY---AAMKFFLYTLAGSLLMLLAILGLYFLGGGTFD 188

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588   88 KEIIPSMMISSS----LLLKIGAA--------PFHFWFPEVMGSSSWINCLTLM-TWQKIAPMMVLSYCIKM-------- 146
Cdd:TIGR01972 189 LLELLNLPLPFGvqtwLFLAFFIAfavkvplfPLHTWLPDAHVEAPTAGSVILAgVLLKMGTYGFLRFNLPLfpdaslyf 268

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 435855588  147 GMFIFLINILSIIIGALGGLNQTSLRQILAYSSISHLGWMM 187
Cdd:TIGR01972 269 APVLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVL 309
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 1-187 8.28e-03

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 38.05  E-value: 8.28e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588   1 MNNNSMKLLFLSTLMMGTILSISSNTWIGVWMGLEINLL-SFIPMLANNKNMmmNESAIKYFIVQAMASTMLLFSILLIQ 79
Cdd:PRK08668  94 TKNDAYFNMFALMSLAGVLGVFLANDLLTLYIFWEIMTFsSFMMVPMGKKES--RKASLKYFVLSAIGAYAMLYAIFLIY 171

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 435855588  80 MKNPIEWGKEIIPSMMISSSL--------------LLKIGAAPFHFWFPEVMGSSS-------------------WINCL 126
Cdd:PRK08668 172 AKTGTFDFADISQGLINDTSTgfalivflfllafgVAKAGIFPLHVWAPDAYSEAPqsfsavlsgqlsklgaygfLLVLY 251

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 435855588 127 TLMTWQKIAPMMVLSYCIKMGMFIFLINILSIIIGALGGLNQTSLRQILAYSSISHLGWMM 187
Cdd:PRK08668 252 VLPGTKLFSEFGTYRGVPLFNYILAWLGNISIIVGTLMAILQEDIKKLIAYSSVANGGYIL 312
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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