|
Name |
Accession |
Description |
Interval |
E-value |
| PRK13709 |
PRK13709 |
conjugal transfer nickase/helicase TraI; Provisional |
2-1083 |
0e+00 |
|
conjugal transfer nickase/helicase TraI; Provisional
Pssm-ID: 237478 [Multi-domain] Cd Length: 1747 Bit Score: 1707.31 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 2 LSFSVVKSAGSAGNYYTDKDNYYVLGSMGERWAGQGAEQLGLQGSVDKDVFTRLLEGRLPDGADLSRMQDGSNKHRPGYD 81
Cdd:PRK13709 1 MSIAQVKSAGSAGNYYTDKDNYYVLGSMGERWAGEGAEQLGLQGSVDKDVFTRLLEGRLPDGADLSRMQDGSNKHRPGYD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 82 LTFSAPKSVSMMAMLGGDKRLIDAHNQAVDFAVRQVEALASTRVMTDGQSETVLTGNLVMALFNHDTSRDQDPQLHTHVV 161
Cdd:PRK13709 81 LTFSAPKSVSMMAMLGGDKRLIEAHNQAVDFAVRQVEALASTRVMTDGQSETVLTGNLVMALFNHDTSRDQDPQLHTHAV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 162 VANVTQHNGEWKTLSSDKVGKTGFSENVLANRIAFGKIYQSELRQRVEALGYETEVVGKHGMWEMPGVPVEAFSGRSQAI 241
Cdd:PRK13709 161 VANVTQHNGKWKTLSSDKVGKTGFIENVYANQIAFGKIYREALKEDVEALGYETEVVGKHGMWEMKGVPVEAFSSRSQEI 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 242 REAVGEDASLKSRDVAALDTRKSKQHVDPEVRMAEWMQTLKETGFDIRAYRDAADQRAEIRTQAPGPASQDGPDVQQAVT 321
Cdd:PRK13709 241 REAVGEDASLKSRDVAALDTRKSKQHVDPEVRMAEWMQTLKETGFDIRAYREAADQRAEIRTQAPGPASQDGPDIQQAVT 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 322 QAIAGLSERKVQFTYTDVLARTVGILPPENGVIERARAGIDEAISREQLIPLDREKGLFTSGIHVLDELSVRALSRDIMK 401
Cdd:PRK13709 321 QAIAGLSDRKVQFTYTDLLARTVGILPPENGVIERARAGIDEAISREQLIPLDREKGLFTSGIHVLDELSVRALSRDIMK 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 402 QNRVTVHPEKSVPRTAGYSDAVSVLAQDRPSLAIVSGQGGAAGQRERVAELVMMAREQGREVQIIAADRRSQMNLKQDER 481
Cdd:PRK13709 401 QNRVTVHPEKSVPRTAGYSDAVSVLAQDRPSLAIVSGQGGAAGQRERVAELVMMAREQGREVQILAADRRSQMNLKQDER 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 482 LSGELITGRRQLLEGMAFPPGSTVIVDQGEKLSLKETLTLLDGAARHNVQVLITDSGQRTGTGSALMAMKDAGVNTYRWQ 561
Cdd:PRK13709 481 LSGELITGRRQLQEGMAFTPGSTLIVDQAEKLSLKETLTLLDGAARHNVQVLILDSGQRTGTGSALMVLKDAGVNTYRWQ 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 562 GGEQRPATIISEPDRNVRYARLAGDFAASVKAGEESVAQVSGVREQAILTEAIRSELKTQGVLGHPEVTMTALSPVWLDS 641
Cdd:PRK13709 561 GGEQRPATVISEPDKNVRYARLAGDFAASVKAGEESVAQVSGVREQAILTGLIRSALKTQGVLGRPEVTITALSPVWLDS 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 642 RSRYLRDMYRPGMVMEQWNPETRSHDRYVIDRVTAQSHSLTLRDAQGETQVVRISSLDSSWSLFRPEKMPVADGERLRVT 721
Cdd:PRK13709 641 KSRYLRDMYRPGMVMEQWNPETRSHDRYVIDRVTAQSHSLTLRDAQGETQVVKISSLDSSWSLFRPEKMPVADGERLRVL 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 722 GKIPGLRVSGGDRLQVASVSEDAMTVVVPGRAEPATLPVADSPFTALKLENGWVETPGHSVSDSATVFASVTQMAMDNAT 801
Cdd:PRK13709 721 GKIPGLRLKGGDRLQVTSVSEDGLTVVVPGRAEPATLPVDDSPFTALKLEHGWVETPGHSVSDSATVFASVTQRAMDNAT 800
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 802 LNGLARSGRDVRLYSSLDEPRTAEKLAR------------QRSGE---------------TPD----------------- 837
Cdd:PRK13709 801 LNGLARSGRDVRLYSSLDETRTAEKLARhpsftvvseqikARAGEtdletaislqkaglhTPAqqaihlalpvlesknla 880
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 838 FSnTLFLLDE------------------SSMVGNTDM---------------ARA--------YALIAAGGG-------- 868
Cdd:PRK13709 881 FS-MVDLLTEaksfaaegtsftelggeiNAQIKRGDLlyvdvakgygtgllvSRAsyeaeksiLRHILEGKEavtplmer 959
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 869 ------------------------------------------RAVASG-------------------------------- 874
Cdd:PRK13709 960 vpgelmegltsgqraatrmilestdrftvvqgyagvgkttqfRAVMSAvntlpeserprvvglgpthravgemrsagvda 1039
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 875 --------DTDQLQ---------------------------------------AIAPGQPFRLQQTRSAADVVIMKE--- 904
Cdd:PRK13709 1040 qtlasflhDTQLQQrsgetpdfsntlflldessmvgntdmarayaliaagggrAVSSGDTDQLQAIAPGQPFRLMQTrsa 1119
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 905 --------IVRQTPELREAVYSLINRDVERALSGLESVKPSQVPRQEGAWAPEHSVTEFSHSQEAKLAEAQQKAMLkgeA 976
Cdd:PRK13709 1120 advaimkeIVRQTPELREAVYSLINRDVERALSGIESVKPSQVPRQEGAWAPESSVTEFSHPQEAKLAEAQQKAML---A 1196
|
1210 1220 1230 1240 1250 1260 1270 1280
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 977 FPDIPMTLYEAIVRDYTGRTPEAREQTLIVTHLNEDRRVLNSMIHDAREKAGELGKEQVMVPVLNTANIRDGELRRLSTW 1056
Cdd:PRK13709 1197 FPDVPMTLYEAIVRDYTGRTPEAREQTLIITHLNEDRRVLNSMIHDAREKAGELGKEQVTVPVLDTANIRDGELRRLSTW 1276
|
1290 1300
....*....|....*....|....*..
gi 431482973 1057 ENNPDALALVDSVYHRIAGISKDDGLI 1083
Cdd:PRK13709 1277 EAHRGALALVDNVYHRIAGIDKDDGLI 1303
|
|
| TraI_TIGR |
TIGR02760 |
conjugative transfer relaxase protein TraI; This protein is a component of the relaxosome ... |
1-832 |
0e+00 |
|
conjugative transfer relaxase protein TraI; This protein is a component of the relaxosome complex. In the process of conjugative plasmid transfer the realaxosome binds to the plasmid at the oriT (origin of transfer) site. The relaxase protein TraI mediates the single-strand nicking and ATP-dependent unwinding (relaxation, helicase activity) of the plasmid molecule. These two activities reside in separate domains of the protein.
Pssm-ID: 274285 [Multi-domain] Cd Length: 1960 Bit Score: 1026.38 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 1 MLSFSVVKSAGSAGNYYTDKDNYYVLGSM---GERWAGQGAEQLGLQG-SVDKDVFTRLLEGRLPDGADLSRMQDGSNKH 76
Cdd:TIGR02760 1 MMSISPLRSAGDAAAYYLDEDNYYLKDSKslnNTRWLGKGAEQLGLLGkPVEKEQFEALLSGTLPDGTQLGRIDKGGIHH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 77 RPGYDLTFSAPKSVSMMAMLGGDKRLIDAHNQAVDFAVRQVEA-LASTRVMTDGQSETVLTGNLVMALFNHDTSRDQDPQ 155
Cdd:TIGR02760 81 RPGFDLTFSAPKSVSILALVGGDKRLIEAHDKAVKIAVSEMEKdAAQARQTVDGKTEFINTRNLVFAMFRHKTSRENDPQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 156 LHTHVVVANVTQ-HNGEWKTLSSDKVGKTGF----SENVLANRIAFGKIYQSELRQRVEALGYETEVVGKhGMWEMPGVP 230
Cdd:TIGR02760 161 LHTHAVVQNMTHdSDGKWRSLASDMKGQKGViegfRERIYNHQIYYGLLYRSKLAKKVEELGYQTASVGK-GQFEIQGVP 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 231 ---VEAFSGRSQAIREAVGEDA--SLKSRDVAALDTRKSKQHVDPEVRMAEWMQTLKETGFDIRAYRDAADQRAEIRTQA 305
Cdd:TIGR02760 240 eqvLTAFSKRRQQIDELVDEKGwsSAKARDIAALDTRKDKTYIDDETLMEKWQQECKDMGFDPHALVASSYKPENIVARF 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 306 PGPASQDgpdVQQAVTQAIAGLSERKVQFTYTDVLARTVGILPPENGVIER--ARAGIDEAISREQLIPLDREKGLFTSG 383
Cdd:TIGR02760 320 YGPSQID---AQHAVEVAIAHLSQYSTQFEYEKLIEEAAKYFTAGNKIIDEidIKKAIDELIANGQLIPLFTQKGLFTTQ 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 384 IHVLDELSVRALSRDIMKQNRVTVHPEKSV--PRTAGYSDAVSVLAQDRPSLAIVSGQGGAaGQRERVAELVMMAREQGR 461
Cdd:TIGR02760 397 TMLTNEKELIARTEGGKGALRVIVSKQKLSefALSPSNKDAVSTLFTSTKRFIIINGFGGT-GSTEIAQLLLHLASEQGY 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 462 EVQIIAADRRSQMNLKQD-ERLSGELITGRRQLLEGM-------------AFPPGSTVIVDQGEKLSLKETLTLLDGAAR 527
Cdd:TIGR02760 476 EIQIITAGSLSAQELRQKiPRLASTFITWVKNLFNDDqdhtvqglldkssPFSNKDIFVVDEANKLSNNELLKLIDKAEQ 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 528 HNVQ-VLITDSGQRTG--TGSALMAMKDAGVNTYRWQGGEQRPATI-ISEPDRNVRYARLAGDFAASVKAGEESVAQVSG 603
Cdd:TIGR02760 556 HNSKlILLNDSAQRQGmsAGSAIDLLKEGGVTTYAWVDTKQQKASVeISEAVDKLRVDYIASAWLDLTPDRQNSQVLATT 635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 604 VREQAILTEAIRSELKTQGVLGHPEVTMTALSPVWLDSRSRYLRDMYRPGMVMEQWNPETRSHDRYVIDRVTAQSHSLTL 683
Cdd:TIGR02760 636 HREQQDLTQIIRNALKQEGQLSRQEVTVPTLKPVNLTGIQRRNAAHYKQGMVIRFWQKGKIPHDDYVVTNVNKHNNTLTL 715
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 684 RDAQGETQVVRISSL---DSSWSLFRPEKMPVADGERLRVTGKIPGLRVSGGDRLQVASVSEDAMTVV-VPGRaepaTLP 759
Cdd:TIGR02760 716 KDAQGKTQKFKPSSLkdlERPFSVYRPEQLEVAAGERLQVTGNHFHSRVRNGELLTVSSINNEGITLItEDGQ----TLH 791
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 431482973 760 VADSPFTALKLENGWVETPGHSVSDSATVFASVTQMAMDNATLNGLARSGRDVRLYSSLDE--PRTAEKLARQRS 832
Cdd:TIGR02760 792 LPHGALEDAHLDYGYVLTPYHTQPDDAKVFLGVKQYALSKALLNSLNRSASRVDLFTDLDEkaQRYLEKTRGIPS 866
|
|
| MobF |
NF041492 |
MobF family relaxase; |
1-281 |
1.03e-116 |
|
MobF family relaxase;
Pssm-ID: 469380 [Multi-domain] Cd Length: 288 Bit Score: 361.62 E-value: 1.03e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 1 MLSFSVVKSAGSAGNYYTDKD--NYYVLG--SMGERWAGQGAEQLGL-QGSVDKDVFTRLLEGRLPDGADLSRMQDGSNK 75
Cdd:NF041492 1 MLSIARIGSAGGAARYYTEKDldNYYSEDggTPAGRWFGKGAEALGLsGGAVDGERFKALLDGRLPDGERLRRRRKGAGR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 76 HRPGYDLTFSAPKSVSMMAMLGGDKRLIDAHNQAVDFAVR-QVEALASTRVMTDGQSETVL--TGNLVMALFNHDTSRDQ 152
Cdd:NF041492 81 HRPGYDLTFSAPKSVSLLALVGGDKRLIEAHDEAVKEALEyLEERLAQTRVTVDGKGRTSLekTGNLVAALFRHDTSRAG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 153 DPQLHTHVVVANVTQH-NGEWKTLSsdkvgktgfSENVLANRIAFGKIYQSELRQRVEALGYETEVVgKHGMWEMPGVP- 230
Cdd:NF041492 161 DPQLHTHAVVMNMTQRpDGKWRSLD---------NEELYKNQKALGAIYQAELAEELQALGYEIRET-KNGQFEIAGVPr 230
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 431482973 231 --VEAFSGRSQAIREAVGED----ASLKSRDVAALDTRKSKQ-HVDPEVRMAEWMQTL 281
Cdd:NF041492 231 eqIEAFSKRSQQIEEWLGENpatlASAALRQIAALDTRKAKEaDVDPEELEAEWREEA 288
|
|
| TrwC |
pfam08751 |
TrwC relaxase; Relaxases are DNA strand transferases which function during the conjugative ... |
10-283 |
6.94e-102 |
|
TrwC relaxase; Relaxases are DNA strand transferases which function during the conjugative cell to cell DNA transfer. TrwC binds to the origin of transfer (oriT) and melts the double helix.
Pssm-ID: 430190 [Multi-domain] Cd Length: 279 Bit Score: 321.87 E-value: 6.94e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 10 AGSAGNYYTDKDNYYVL-GSMGERWAGQGAEQLGLQGSVDKDVFTRLLEGRLPD-GADLSRMQDGSNKHRPGYDLTFSAP 87
Cdd:pfam08751 1 AGDAYAYYTRQDDYYTEgGEPPGRWLGKGAAALGLSGEVTEEQFEALLEGRHPDtGERLGRRRPRGRKHRAGFDLTFSAP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 88 KSVSMMAMLGGDKRLIDAHNQAVDFAVRQVEA-LASTRVMTDGQSETVLTGNLVMALFNHDTSRDQDPQLHTHVVVANVT 166
Cdd:pfam08751 81 KSVSLLAAVGGDERIEAAHRAAVAEALAWLEKhAAQTRVGKDGGVEQVDTGGLVAAAFRHDTSRAGDPQLHTHVVVANVT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 167 Q-HNGEWKTLSSDKVGKtgfsenvlaNRIAFGKIYQSELRQRVEALGYETEVVGKHGMWEMPGVP---VEAFSGRSQAIR 242
Cdd:pfam08751 161 QrEDGKWRALDSRGLYK---------AQVAAGAVYRAELADELRRLGYEIEERGKRGVFEIAGVPeelIEAFSKRRAQIE 231
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 431482973 243 EAVGE------DASLKSRDVAALDTRKSK-QHVDPEVRMAEWMQTLKE 283
Cdd:pfam08751 232 AELAElgathgRAPPAARQIAALETRPAKhEPRSLAELRARWREEAAE 279
|
|
| RecD |
COG0507 |
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) ... |
834-1047 |
6.02e-16 |
|
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];
Pssm-ID: 440273 [Multi-domain] Cd Length: 514 Bit Score: 82.33 E-value: 6.02e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 834 ETPDFSNTLFLLDESSMVGNTDMARAYALIAAGGGRAVASGDTDQLQAIAPGQPFRLQQTRSAADVVIMKEIVRQTPELR 913
Cdd:COG0507 213 DNPLTPADLLVVDEASMVDTRLMAALLEALPRAGARLILVGDPDQLPSVGAGAVLRDLIESGTVPVVELTEVYRQADDSR 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 914 EAVYS-LINR-DVERALSglesvkpsqvprqegAWAPEHSVTEFSHSQEAKlaeaqqkamlkgeafpdipmtlyEAIVRD 991
Cdd:COG0507 293 IIELAhAIREgDAPEALN---------------ARYADVVFVEAEDAEEAA-----------------------EAIVEL 334
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 431482973 992 YTGRtPEAREQTLIVTHLNEDRRVLNSMIHDAREKAGELGKEQVMV---------PVLNTANIRD 1047
Cdd:COG0507 335 YADR-PAGGEDIQVLAPTNAGVDALNQAIREALNPAGELERELAEDgelelyvgdRVMFTRNDYD 398
|
|
| DEXSc_RecD-like |
cd17933 |
DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1. ... |
829-906 |
2.68e-14 |
|
DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1.11.5, Exonuclease V) complex. It is the alpha chain of the complex and functions as a 3'-5' helicase. The RecBCD enzyme is both a helicase that unwinds, or separates the strands of DNA, and a nuclease that makes single-stranded nicks in DNA. RecD is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350691 [Multi-domain] Cd Length: 155 Bit Score: 71.43 E-value: 2.68e-14
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 431482973 829 RQRSGETPDFSNTLFLLDESSMVGNTDMARAYALIAAGGgRAVASGDTDQLQAIAPGQPFRLQQTRSAADVVIMKEIV 906
Cdd:cd17933 79 GFYYNEENPLDADLLIVDEASMVDTRLMAALLSAIPAGA-RLILVGDPDQLPSVGAGNVLRDLIASKGVPTVELTEVF 155
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK13709 |
PRK13709 |
conjugal transfer nickase/helicase TraI; Provisional |
2-1083 |
0e+00 |
|
conjugal transfer nickase/helicase TraI; Provisional
Pssm-ID: 237478 [Multi-domain] Cd Length: 1747 Bit Score: 1707.31 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 2 LSFSVVKSAGSAGNYYTDKDNYYVLGSMGERWAGQGAEQLGLQGSVDKDVFTRLLEGRLPDGADLSRMQDGSNKHRPGYD 81
Cdd:PRK13709 1 MSIAQVKSAGSAGNYYTDKDNYYVLGSMGERWAGEGAEQLGLQGSVDKDVFTRLLEGRLPDGADLSRMQDGSNKHRPGYD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 82 LTFSAPKSVSMMAMLGGDKRLIDAHNQAVDFAVRQVEALASTRVMTDGQSETVLTGNLVMALFNHDTSRDQDPQLHTHVV 161
Cdd:PRK13709 81 LTFSAPKSVSMMAMLGGDKRLIEAHNQAVDFAVRQVEALASTRVMTDGQSETVLTGNLVMALFNHDTSRDQDPQLHTHAV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 162 VANVTQHNGEWKTLSSDKVGKTGFSENVLANRIAFGKIYQSELRQRVEALGYETEVVGKHGMWEMPGVPVEAFSGRSQAI 241
Cdd:PRK13709 161 VANVTQHNGKWKTLSSDKVGKTGFIENVYANQIAFGKIYREALKEDVEALGYETEVVGKHGMWEMKGVPVEAFSSRSQEI 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 242 REAVGEDASLKSRDVAALDTRKSKQHVDPEVRMAEWMQTLKETGFDIRAYRDAADQRAEIRTQAPGPASQDGPDVQQAVT 321
Cdd:PRK13709 241 REAVGEDASLKSRDVAALDTRKSKQHVDPEVRMAEWMQTLKETGFDIRAYREAADQRAEIRTQAPGPASQDGPDIQQAVT 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 322 QAIAGLSERKVQFTYTDVLARTVGILPPENGVIERARAGIDEAISREQLIPLDREKGLFTSGIHVLDELSVRALSRDIMK 401
Cdd:PRK13709 321 QAIAGLSDRKVQFTYTDLLARTVGILPPENGVIERARAGIDEAISREQLIPLDREKGLFTSGIHVLDELSVRALSRDIMK 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 402 QNRVTVHPEKSVPRTAGYSDAVSVLAQDRPSLAIVSGQGGAAGQRERVAELVMMAREQGREVQIIAADRRSQMNLKQDER 481
Cdd:PRK13709 401 QNRVTVHPEKSVPRTAGYSDAVSVLAQDRPSLAIVSGQGGAAGQRERVAELVMMAREQGREVQILAADRRSQMNLKQDER 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 482 LSGELITGRRQLLEGMAFPPGSTVIVDQGEKLSLKETLTLLDGAARHNVQVLITDSGQRTGTGSALMAMKDAGVNTYRWQ 561
Cdd:PRK13709 481 LSGELITGRRQLQEGMAFTPGSTLIVDQAEKLSLKETLTLLDGAARHNVQVLILDSGQRTGTGSALMVLKDAGVNTYRWQ 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 562 GGEQRPATIISEPDRNVRYARLAGDFAASVKAGEESVAQVSGVREQAILTEAIRSELKTQGVLGHPEVTMTALSPVWLDS 641
Cdd:PRK13709 561 GGEQRPATVISEPDKNVRYARLAGDFAASVKAGEESVAQVSGVREQAILTGLIRSALKTQGVLGRPEVTITALSPVWLDS 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 642 RSRYLRDMYRPGMVMEQWNPETRSHDRYVIDRVTAQSHSLTLRDAQGETQVVRISSLDSSWSLFRPEKMPVADGERLRVT 721
Cdd:PRK13709 641 KSRYLRDMYRPGMVMEQWNPETRSHDRYVIDRVTAQSHSLTLRDAQGETQVVKISSLDSSWSLFRPEKMPVADGERLRVL 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 722 GKIPGLRVSGGDRLQVASVSEDAMTVVVPGRAEPATLPVADSPFTALKLENGWVETPGHSVSDSATVFASVTQMAMDNAT 801
Cdd:PRK13709 721 GKIPGLRLKGGDRLQVTSVSEDGLTVVVPGRAEPATLPVDDSPFTALKLEHGWVETPGHSVSDSATVFASVTQRAMDNAT 800
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 802 LNGLARSGRDVRLYSSLDEPRTAEKLAR------------QRSGE---------------TPD----------------- 837
Cdd:PRK13709 801 LNGLARSGRDVRLYSSLDETRTAEKLARhpsftvvseqikARAGEtdletaislqkaglhTPAqqaihlalpvlesknla 880
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 838 FSnTLFLLDE------------------SSMVGNTDM---------------ARA--------YALIAAGGG-------- 868
Cdd:PRK13709 881 FS-MVDLLTEaksfaaegtsftelggeiNAQIKRGDLlyvdvakgygtgllvSRAsyeaeksiLRHILEGKEavtplmer 959
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 869 ------------------------------------------RAVASG-------------------------------- 874
Cdd:PRK13709 960 vpgelmegltsgqraatrmilestdrftvvqgyagvgkttqfRAVMSAvntlpeserprvvglgpthravgemrsagvda 1039
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 875 --------DTDQLQ---------------------------------------AIAPGQPFRLQQTRSAADVVIMKE--- 904
Cdd:PRK13709 1040 qtlasflhDTQLQQrsgetpdfsntlflldessmvgntdmarayaliaagggrAVSSGDTDQLQAIAPGQPFRLMQTrsa 1119
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 905 --------IVRQTPELREAVYSLINRDVERALSGLESVKPSQVPRQEGAWAPEHSVTEFSHSQEAKLAEAQQKAMLkgeA 976
Cdd:PRK13709 1120 advaimkeIVRQTPELREAVYSLINRDVERALSGIESVKPSQVPRQEGAWAPESSVTEFSHPQEAKLAEAQQKAML---A 1196
|
1210 1220 1230 1240 1250 1260 1270 1280
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 977 FPDIPMTLYEAIVRDYTGRTPEAREQTLIVTHLNEDRRVLNSMIHDAREKAGELGKEQVMVPVLNTANIRDGELRRLSTW 1056
Cdd:PRK13709 1197 FPDVPMTLYEAIVRDYTGRTPEAREQTLIITHLNEDRRVLNSMIHDAREKAGELGKEQVTVPVLDTANIRDGELRRLSTW 1276
|
1290 1300
....*....|....*....|....*..
gi 431482973 1057 ENNPDALALVDSVYHRIAGISKDDGLI 1083
Cdd:PRK13709 1277 EAHRGALALVDNVYHRIAGIDKDDGLI 1303
|
|
| PRK14712 |
PRK14712 |
conjugal transfer nickase/helicase TraI; Provisional |
134-1084 |
0e+00 |
|
conjugal transfer nickase/helicase TraI; Provisional
Pssm-ID: 237796 [Multi-domain] Cd Length: 1623 Bit Score: 1520.55 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 134 VLTGNLVMALFNHDTSRDQDPQLHTHVVVANVTQHNGEWKTLSSDKVGKTGFSENVLANRIAFGKIYQSELRQRVEALGY 213
Cdd:PRK14712 1 VLTGNLVMALFNHDTSRDQEPQLHTHAVVANVTQHNGEWKTLSSDKVGKTGFIENVYANQIAFGRLYREKLKEQVEALGY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 214 ETEVVGKHGMWEMPGVPVEAFSGRSQAIREAVGEDASLKSRDVAALDTRKSKQHVDPEVRMAEWMQTLKETGFDIRAYRD 293
Cdd:PRK14712 81 ETEVVGKHGMWEMPGVPVEAFSGRSQTIREAVGEDASLKSRDVAALDTRKSKQHVDPEVRMAEWMQTLKETGFDIRAYRD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 294 AADQRAEIRTQAPGPASQDGPDVQQAVTQAIAGLSERKVQFTYTDVLARTVGILPPENGVIERARAGIDEAISREQLIPL 373
Cdd:PRK14712 161 AAEQRAYTRTQTPGPASQDGPDVQQAVTQAIAGLSERKVQFMYTDLLARTVGILPPENGVIERARAGIDEAISREQLIPL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 374 DREKGLFTSGIHVLDELSVRALSRDIMKQNRVTVHPEKSVPRTAGYSDAVSVLAQDRPSLAIVSGQGGAAGQRERVAELV 453
Cdd:PRK14712 241 DREKGLFTSGIHMLDELSVRALSRDIMKQNRVTVHPEKSVPRTAGYSDAVSVLAQDRPSLAIVSGQGGAAGQRERVAELV 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 454 MMAREQGREVQIIAADRRSQMNLKQDERLSGELITGRRQLLEGMAFPPGSTVIVDQGEKLSLKETLTLLDGAARHNVQVL 533
Cdd:PRK14712 321 MMAREQGREVQIIAADRRSQMNLKQDERLSGELITGRRQLLEGMAFTPGSTVIVDQGEKLSLKETLTLLDGAARHNVQVL 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 534 ITDSGQRTGTGSALMAMKDAGVNTYRWQGGEQRPATIISEPDRNVRYARLAGDFAASVKAGEESVAQVSGVREQAILTEA 613
Cdd:PRK14712 401 ITDSGQRTGTGSALMAMKDAGVNTYRWQGGEQRPATIISEPDRNVRYARLAGDFAASVKAGEESVAQVSGVREQAILTQA 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 614 IRSELKTQGVLGHPEVTMTALSPVWLDSRSRYLRDMYRPGMVMEQWNPETRSHDRYVIDRVTAQSHSLTLRDAQGETQVV 693
Cdd:PRK14712 481 IRSELKTQGVLGHPEVTMTALSPVWLDSRSRYLRDMYRPGMVMEQWNPETRSHDRYVTERVTAQSHSLTLRNAQGETQVV 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 694 RISSLDSSWSLFRPEKMPVADGERLRVTGKIPGLRVSGGDRLQVASVSEDAMTVVVPGRAEPATLPVADSPFTALKLENG 773
Cdd:PRK14712 561 RISSLDSSWSLFRPEKMPVADGERLRVTGKIPGLRVSGGDRLQVASVSEDAMTVVVPGRAEPATLPVSDSPFTALKLENG 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 774 WVETPGHSVSDSATVFASVTQMAMDNATLNGLARSGRDVRLYSSLDEPRTAEKLARQ------------RSGET------ 835
Cdd:PRK14712 641 WVETPGHSVSDSATVFASVTQMAMDNATLNGLARSGRDVRLYSSLDETRTAEKLARHpsftvvseqikaRAGETlletai 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 836 --------------------------PDFSNTLFLLDESSMVG------------NTDMARA---YALIAAGGG------ 868
Cdd:PRK14712 721 slqkaglhtpaqqaihlalpvlesknLAFSMVDLLTEAKSFAAegtgfadlggeiNAQIKRGdllYVDVAKGYGtgllvs 800
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 869 RAVASGDTDQLQAIAPGQ----PF----------RLQQTRSAADVVIMKEIVR--------------------------- 907
Cdd:PRK14712 801 RASYEAEKSILRHILEGKeavtPLmervpgelmeKLTSGQRAATRMILETSDRftvvqgyagvgkttqfravmsavnmlp 880
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 908 --------------------------------------------QTPELREAVYSLI------NRDVERALS-------- 929
Cdd:PRK14712 881 eserprvvglgpthravgemrsagvdaqtlasflhdtqlqqrsgETPDFSNTLFLLDessmvgNTDMARAYAliaagggr 960
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 930 --------GLESVKP----------------------------------------------------SQVPRQEGAWAPE 949
Cdd:PRK14712 961 avasgdtdQLQAIAPgqpfrlqqtrsaadvvimkeivrqtpelreavyslinrdveralsglervkpSQVPRLEGAWAPE 1040
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 950 HSVTEFSHSQEAKLAEAQQKAMLKGEAFPDIPMTLYEAIVRDYTGRTPEAREQTLIVTHLNEDRRVLNSMIHDAREKAGE 1029
Cdd:PRK14712 1041 HSVTEFSHSQEAKLAEAQQKAMLKGEAFPDVPMTLYEAIVRDYTGRTPEAREQTLIVTHLNEDRRVLNSMIHDAREKAGE 1120
|
1130 1140 1150 1160 1170
....*....|....*....|....*....|....*....|....*....|....*
gi 431482973 1030 LGKEQVMVPVLNTANIRDGELRRLSTWENNPDALALVDSVYHRIAGISKDDGLIS 1084
Cdd:PRK14712 1121 LGQVQVMVPVLNTANIRDGELRRLSTWENNPDALALVDNVYHRIAGISKDDGLIT 1175
|
|
| TraI_TIGR |
TIGR02760 |
conjugative transfer relaxase protein TraI; This protein is a component of the relaxosome ... |
1-832 |
0e+00 |
|
conjugative transfer relaxase protein TraI; This protein is a component of the relaxosome complex. In the process of conjugative plasmid transfer the realaxosome binds to the plasmid at the oriT (origin of transfer) site. The relaxase protein TraI mediates the single-strand nicking and ATP-dependent unwinding (relaxation, helicase activity) of the plasmid molecule. These two activities reside in separate domains of the protein.
Pssm-ID: 274285 [Multi-domain] Cd Length: 1960 Bit Score: 1026.38 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 1 MLSFSVVKSAGSAGNYYTDKDNYYVLGSM---GERWAGQGAEQLGLQG-SVDKDVFTRLLEGRLPDGADLSRMQDGSNKH 76
Cdd:TIGR02760 1 MMSISPLRSAGDAAAYYLDEDNYYLKDSKslnNTRWLGKGAEQLGLLGkPVEKEQFEALLSGTLPDGTQLGRIDKGGIHH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 77 RPGYDLTFSAPKSVSMMAMLGGDKRLIDAHNQAVDFAVRQVEA-LASTRVMTDGQSETVLTGNLVMALFNHDTSRDQDPQ 155
Cdd:TIGR02760 81 RPGFDLTFSAPKSVSILALVGGDKRLIEAHDKAVKIAVSEMEKdAAQARQTVDGKTEFINTRNLVFAMFRHKTSRENDPQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 156 LHTHVVVANVTQ-HNGEWKTLSSDKVGKTGF----SENVLANRIAFGKIYQSELRQRVEALGYETEVVGKhGMWEMPGVP 230
Cdd:TIGR02760 161 LHTHAVVQNMTHdSDGKWRSLASDMKGQKGViegfRERIYNHQIYYGLLYRSKLAKKVEELGYQTASVGK-GQFEIQGVP 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 231 ---VEAFSGRSQAIREAVGEDA--SLKSRDVAALDTRKSKQHVDPEVRMAEWMQTLKETGFDIRAYRDAADQRAEIRTQA 305
Cdd:TIGR02760 240 eqvLTAFSKRRQQIDELVDEKGwsSAKARDIAALDTRKDKTYIDDETLMEKWQQECKDMGFDPHALVASSYKPENIVARF 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 306 PGPASQDgpdVQQAVTQAIAGLSERKVQFTYTDVLARTVGILPPENGVIER--ARAGIDEAISREQLIPLDREKGLFTSG 383
Cdd:TIGR02760 320 YGPSQID---AQHAVEVAIAHLSQYSTQFEYEKLIEEAAKYFTAGNKIIDEidIKKAIDELIANGQLIPLFTQKGLFTTQ 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 384 IHVLDELSVRALSRDIMKQNRVTVHPEKSV--PRTAGYSDAVSVLAQDRPSLAIVSGQGGAaGQRERVAELVMMAREQGR 461
Cdd:TIGR02760 397 TMLTNEKELIARTEGGKGALRVIVSKQKLSefALSPSNKDAVSTLFTSTKRFIIINGFGGT-GSTEIAQLLLHLASEQGY 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 462 EVQIIAADRRSQMNLKQD-ERLSGELITGRRQLLEGM-------------AFPPGSTVIVDQGEKLSLKETLTLLDGAAR 527
Cdd:TIGR02760 476 EIQIITAGSLSAQELRQKiPRLASTFITWVKNLFNDDqdhtvqglldkssPFSNKDIFVVDEANKLSNNELLKLIDKAEQ 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 528 HNVQ-VLITDSGQRTG--TGSALMAMKDAGVNTYRWQGGEQRPATI-ISEPDRNVRYARLAGDFAASVKAGEESVAQVSG 603
Cdd:TIGR02760 556 HNSKlILLNDSAQRQGmsAGSAIDLLKEGGVTTYAWVDTKQQKASVeISEAVDKLRVDYIASAWLDLTPDRQNSQVLATT 635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 604 VREQAILTEAIRSELKTQGVLGHPEVTMTALSPVWLDSRSRYLRDMYRPGMVMEQWNPETRSHDRYVIDRVTAQSHSLTL 683
Cdd:TIGR02760 636 HREQQDLTQIIRNALKQEGQLSRQEVTVPTLKPVNLTGIQRRNAAHYKQGMVIRFWQKGKIPHDDYVVTNVNKHNNTLTL 715
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 684 RDAQGETQVVRISSL---DSSWSLFRPEKMPVADGERLRVTGKIPGLRVSGGDRLQVASVSEDAMTVV-VPGRaepaTLP 759
Cdd:TIGR02760 716 KDAQGKTQKFKPSSLkdlERPFSVYRPEQLEVAAGERLQVTGNHFHSRVRNGELLTVSSINNEGITLItEDGQ----TLH 791
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 431482973 760 VADSPFTALKLENGWVETPGHSVSDSATVFASVTQMAMDNATLNGLARSGRDVRLYSSLDE--PRTAEKLARQRS 832
Cdd:TIGR02760 792 LPHGALEDAHLDYGYVLTPYHTQPDDAKVFLGVKQYALSKALLNSLNRSASRVDLFTDLDEkaQRYLEKTRGIPS 866
|
|
| relax_trwC |
TIGR02686 |
conjugative relaxase domain, TrwC/TraI family; This domain is in the N-terminal (relaxase) ... |
13-288 |
4.20e-140 |
|
conjugative relaxase domain, TrwC/TraI family; This domain is in the N-terminal (relaxase) region of TrwC, a relaxase-helicase that acts in plasmid R388 conjugation. The relaxase domain has DNA cleavage and strand transfer activities. Plasmid transfer protein TraI is also a member of this domain family. Members of this family on bacterial chromosomes typically are found near other genes typical of conjugative plasmids and appear to mark integrated plasmids. [Mobile and extrachromosomal element functions, Plasmid functions]
Pssm-ID: 274258 [Multi-domain] Cd Length: 283 Bit Score: 423.02 E-value: 4.20e-140
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 13 AGNYYTDKDNYYVLGSMGERWAGQGAEQLGLQGSVDKDVFTRLLEGRLPDGADLSRMQDGSNKHRPGYDLTFSAPKSVSM 92
Cdd:TIGR02686 1 AADYYTDGDNYYLKDSDAGRWLGKGAQELGLSGEVEKKQFEALLEGRLPDGTRLGRIEDRQSKHRPGFDLTFSAPKSVSI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 93 MAMLGGDKRLIDAHNQAVDFAVRQVEA-LASTRVMTDGQSETVLTGNLVMALFNHDTSRDQDPQLHTHVVVANVTQH-NG 170
Cdd:TIGR02686 81 LALVGGDPRLIDAHDEAVKFTLEQLEKeAAAARVTQDGEIEFEKTGNLVIALFRHDTSRANDPQLHTHAVVANMTRRsDG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 171 EWKTLSSDKVGKTGFSENVLANRIAFGKIYQSELRQRVEALGYETEVVGKHGMWEMPGVP---VEAFSGRSQAIREAVGE 247
Cdd:TIGR02686 161 KWRSLSSDKKGKHGFIEEIYKNQIYLGLLYRAKLANELKELGYQTRVYGKHGNFEIDGVPeevIEAFSKRRQQIEEWVAE 240
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 431482973 248 D--ASLKSRDVAALDTRKSKQHVDPEVRMAEWMQTLKETGFDI 288
Cdd:TIGR02686 241 RgwSLAKSRDTAALDTRKKKTVHDREALREEWQQTAKELGFDP 283
|
|
| MobF |
NF041492 |
MobF family relaxase; |
1-281 |
1.03e-116 |
|
MobF family relaxase;
Pssm-ID: 469380 [Multi-domain] Cd Length: 288 Bit Score: 361.62 E-value: 1.03e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 1 MLSFSVVKSAGSAGNYYTDKD--NYYVLG--SMGERWAGQGAEQLGL-QGSVDKDVFTRLLEGRLPDGADLSRMQDGSNK 75
Cdd:NF041492 1 MLSIARIGSAGGAARYYTEKDldNYYSEDggTPAGRWFGKGAEALGLsGGAVDGERFKALLDGRLPDGERLRRRRKGAGR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 76 HRPGYDLTFSAPKSVSMMAMLGGDKRLIDAHNQAVDFAVR-QVEALASTRVMTDGQSETVL--TGNLVMALFNHDTSRDQ 152
Cdd:NF041492 81 HRPGYDLTFSAPKSVSLLALVGGDKRLIEAHDEAVKEALEyLEERLAQTRVTVDGKGRTSLekTGNLVAALFRHDTSRAG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 153 DPQLHTHVVVANVTQH-NGEWKTLSsdkvgktgfSENVLANRIAFGKIYQSELRQRVEALGYETEVVgKHGMWEMPGVP- 230
Cdd:NF041492 161 DPQLHTHAVVMNMTQRpDGKWRSLD---------NEELYKNQKALGAIYQAELAEELQALGYEIRET-KNGQFEIAGVPr 230
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 431482973 231 --VEAFSGRSQAIREAVGED----ASLKSRDVAALDTRKSKQ-HVDPEVRMAEWMQTL 281
Cdd:NF041492 231 eqIEAFSKRSQQIEEWLGENpatlASAALRQIAALDTRKAKEaDVDPEELEAEWREEA 288
|
|
| TrwC |
pfam08751 |
TrwC relaxase; Relaxases are DNA strand transferases which function during the conjugative ... |
10-283 |
6.94e-102 |
|
TrwC relaxase; Relaxases are DNA strand transferases which function during the conjugative cell to cell DNA transfer. TrwC binds to the origin of transfer (oriT) and melts the double helix.
Pssm-ID: 430190 [Multi-domain] Cd Length: 279 Bit Score: 321.87 E-value: 6.94e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 10 AGSAGNYYTDKDNYYVL-GSMGERWAGQGAEQLGLQGSVDKDVFTRLLEGRLPD-GADLSRMQDGSNKHRPGYDLTFSAP 87
Cdd:pfam08751 1 AGDAYAYYTRQDDYYTEgGEPPGRWLGKGAAALGLSGEVTEEQFEALLEGRHPDtGERLGRRRPRGRKHRAGFDLTFSAP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 88 KSVSMMAMLGGDKRLIDAHNQAVDFAVRQVEA-LASTRVMTDGQSETVLTGNLVMALFNHDTSRDQDPQLHTHVVVANVT 166
Cdd:pfam08751 81 KSVSLLAAVGGDERIEAAHRAAVAEALAWLEKhAAQTRVGKDGGVEQVDTGGLVAAAFRHDTSRAGDPQLHTHVVVANVT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 167 Q-HNGEWKTLSSDKVGKtgfsenvlaNRIAFGKIYQSELRQRVEALGYETEVVGKHGMWEMPGVP---VEAFSGRSQAIR 242
Cdd:pfam08751 161 QrEDGKWRALDSRGLYK---------AQVAAGAVYRAELADELRRLGYEIEERGKRGVFEIAGVPeelIEAFSKRRAQIE 231
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 431482973 243 EAVGE------DASLKSRDVAALDTRKSK-QHVDPEVRMAEWMQTLKE 283
Cdd:pfam08751 232 AELAElgathgRAPPAARQIAALETRPAKhEPRSLAELRARWREEAAE 279
|
|
| TraI_TIGR |
TIGR02760 |
conjugative transfer relaxase protein TraI; This protein is a component of the relaxosome ... |
817-1088 |
7.80e-85 |
|
conjugative transfer relaxase protein TraI; This protein is a component of the relaxosome complex. In the process of conjugative plasmid transfer the realaxosome binds to the plasmid at the oriT (origin of transfer) site. The relaxase protein TraI mediates the single-strand nicking and ATP-dependent unwinding (relaxation, helicase activity) of the plasmid molecule. These two activities reside in separate domains of the protein.
Pssm-ID: 274285 [Multi-domain] Cd Length: 1960 Bit Score: 302.98 E-value: 7.80e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 817 SLDEPRTAEKLARqRSGEtpDFSNTLFLLDESSMVGNTDMARAYALIAAGGGRAVASGDTDQLQAIAPGQPFRLQQTRSA 896
Cdd:TIGR02760 1093 TLDSFLTDISLYR-NSGG--DFRNTLFILDESSMVSNFQLTHATELVQKSGSRAVSLGDIAQLQSLAAGKPFELAITFDI 1169
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 897 ADVVIMKEIVRQ--TPELREAVYSLINRDVERALSGLESVKPSQVPRQEGAWAPEHSVTEFSHsQEAKLAEAQQKAMLKG 974
Cdd:TIGR02760 1170 IDTAIMKEIVRQnnSAELKAAHNSLDKRSNPKALELLKNQNPLQHELMQNAAMPEIASDEQGL-QKHDLAKLAVNTEKPK 1248
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 975 EAFPDIPMTLYEAIVRDYTGRTPEAREQTLIVTHLNEDRRVLNSMIHDAREKAGELGKEQVMVPVLNTANIRDGELRRLS 1054
Cdd:TIGR02760 1249 KAQPDATVTLYREIVKDYLSRTPEFRENTLIIAHTNNDRTGIYPFIREGLIKQKELSKQQVTVPRLRSVNISSPELKTMM 1328
|
250 260 270
....*....|....*....|....*....|....
gi 431482973 1055 TWENNpDALALVDSVYHRIAGISKDDGLISEPAH 1088
Cdd:TIGR02760 1329 PFEKG-AVLRLKKDAYLTIADIDREHGKLTVADI 1361
|
|
| TraI_2B |
pfam18340 |
DNA relaxase TraI 2B/2B-like domain; This is the 2B and 2B-like sub-domain found in TraI (EC:5. ... |
633-712 |
1.00e-35 |
|
DNA relaxase TraI 2B/2B-like domain; This is the 2B and 2B-like sub-domain found in TraI (EC:5.99.1.2) a relaxase of F-family plasmids. It contains four domains; a trans-esterase domain that executes the nicking and covalent attachment of the T-strand to the relaxase, a vestigial helicase domain (carrying the 2B/2B-like sub-domain) that operates as an ssDNA-binding domain, an active 5' to 3' helicase domain, and a C-terminal domain that functions as a recruitment platform for relaxosome components. The 2B sub-domains in TraI are formed by residues 625-773 in the vestigial helicase domain and residues 1255-1397 in the active helicase domain. The 2B/2B-like sub-domain interacts with ssDNA where it contributes to the surface area where ssDNA bind. In other words the ssDNA-binding site is located in a groove between the 2B and 2B-like parts of the sub-domain. The sub-domain parts appear to act as clamps holding the ssDNA in place, resulting in the ssDNA being completely surrounded by protein. In previous studies, the 2B/2B-like sub-domain of the TraI vestigial helicase domain has been identified as translocation signal A (TSA) since it contains sequences essential for the recruitment of TraI to the T4S system. Thus, the 2B/2B-like sub-domain plays two major roles in relaxase function: (1) interacting with the DNA and possibly promoting high processivity and (2) mediating recruitment of the relaxosome to the T4S system.
Pssm-ID: 465718 [Multi-domain] Cd Length: 79 Bit Score: 130.09 E-value: 1.00e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 633 ALSPVWLDSRSRYLRDMYRPGMVMEQWNPeTRSHDRYVIDRVTAQSHSLTLRDAQGETQVVRISSLDSSWSLFRPEKMPV 712
Cdd:pfam18340 1 TLTPVWLDSKNRRSRDSYREGMVLERWNG-ARKKQRFTIDRVTEKTNSLTLVDAKGETSTLKISEIDSHWRLFRSDKLEV 79
|
|
| ssDNA_TraI_N |
pfam18272 |
single-stranded DNA binding TraI N-terminal subdomain; This is a subdomain found in TraI ... |
575-625 |
8.72e-19 |
|
single-stranded DNA binding TraI N-terminal subdomain; This is a subdomain found in TraI present in E. coli. Tra1 is a conjugative relaxase that forms part of the Type IV secretion system. This subdomain, referred to as 2A, is located in N-terminal region of the translocation signal (TSA) domain. TSA is known to reside in a larger ssDNA-binding domain.
Pssm-ID: 408086 [Multi-domain] Cd Length: 53 Bit Score: 81.00 E-value: 8.72e-19
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 431482973 575 DRNVRYARLAGDFAASVKAGEESVAQVSGVREQAILTEAIRSELKTQGVLG 625
Cdd:pfam18272 1 DKAQRYGRLAKEFVQAVREGEESVAQVSGPREQAVLAGMIRDELKEEGVLG 51
|
|
| RecD |
COG0507 |
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) ... |
834-1047 |
6.02e-16 |
|
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];
Pssm-ID: 440273 [Multi-domain] Cd Length: 514 Bit Score: 82.33 E-value: 6.02e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 834 ETPDFSNTLFLLDESSMVGNTDMARAYALIAAGGGRAVASGDTDQLQAIAPGQPFRLQQTRSAADVVIMKEIVRQTPELR 913
Cdd:COG0507 213 DNPLTPADLLVVDEASMVDTRLMAALLEALPRAGARLILVGDPDQLPSVGAGAVLRDLIESGTVPVVELTEVYRQADDSR 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 914 EAVYS-LINR-DVERALSglesvkpsqvprqegAWAPEHSVTEFSHSQEAKlaeaqqkamlkgeafpdipmtlyEAIVRD 991
Cdd:COG0507 293 IIELAhAIREgDAPEALN---------------ARYADVVFVEAEDAEEAA-----------------------EAIVEL 334
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 431482973 992 YTGRtPEAREQTLIVTHLNEDRRVLNSMIHDAREKAGELGKEQVMV---------PVLNTANIRD 1047
Cdd:COG0507 335 YADR-PAGGEDIQVLAPTNAGVDALNQAIREALNPAGELERELAEDgelelyvgdRVMFTRNDYD 398
|
|
| AAA_30 |
pfam13604 |
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ... |
804-932 |
4.32e-15 |
|
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. There is a Walker A and Walker B.
Pssm-ID: 433343 [Multi-domain] Cd Length: 191 Bit Score: 74.91 E-value: 4.32e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 804 GLARSGR-DVRLYSSLDEP-RTAEKLARQRSGETPDFSNTLFLLDESSMVGNTDMARAYALIAAGGGRAVASGDTDQLQA 881
Cdd:pfam13604 51 GLAPTGRaAKVLGEELGIPaDTIAKLLHRLGGRAGLDPGTLLIVDEAGMVGTRQMARLLKLAEDAGARVILVGDPRQLPS 130
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 431482973 882 IAPGQPFR-LQQTRsaADVVIMKEIVRQT-PELREAVYSLINRDVERALSGLE 932
Cdd:pfam13604 131 VEAGGAFRdLLAAG--IGTAELTEIVRQRdPWQRAASLALRDGDPAEALDALA 181
|
|
| DEXSc_RecD-like |
cd17933 |
DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1. ... |
829-906 |
2.68e-14 |
|
DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1.11.5, Exonuclease V) complex. It is the alpha chain of the complex and functions as a 3'-5' helicase. The RecBCD enzyme is both a helicase that unwinds, or separates the strands of DNA, and a nuclease that makes single-stranded nicks in DNA. RecD is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350691 [Multi-domain] Cd Length: 155 Bit Score: 71.43 E-value: 2.68e-14
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 431482973 829 RQRSGETPDFSNTLFLLDESSMVGNTDMARAYALIAAGGgRAVASGDTDQLQAIAPGQPFRLQQTRSAADVVIMKEIV 906
Cdd:cd17933 79 GFYYNEENPLDADLLIVDEASMVDTRLMAALLSAIPAGA-RLILVGDPDQLPSVGAGNVLRDLIASKGVPTVELTEVF 155
|
|
| TraA_Ti |
TIGR02768 |
Ti-type conjugative transfer relaxase TraA; This protein contains domains distinctive of a ... |
839-1061 |
2.42e-10 |
|
Ti-type conjugative transfer relaxase TraA; This protein contains domains distinctive of a single strand exonuclease (N-terminus, MobA/MobL, pfam03389) as well as a helicase domain (central region, homologous to the corresponding region of the F-type relaxase TraI, TIGR02760). This protein likely fills the same role as TraI(F), nicking (at the oriT site) and unwinding the coiled plasmid prior to conjugative transfer.
Pssm-ID: 274289 [Multi-domain] Cd Length: 744 Bit Score: 64.83 E-value: 2.42e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 839 SNTLFLLDESSMVGNTDMARAYALIAAGGGRAVASGDTDQLQAIAPGQPFRlqqtrsaadvvimkeivrqtpelreAVys 918
Cdd:TIGR02768 439 DKDVLVIDEAGMVGSRQMARVLKEAEEAGAKVVLVGDPEQLQPIEAGAAFR-------------------------AI-- 491
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 919 linrdVERalsgLESVKPSQVPRQEGAWAPEHSVTEFSHSQEAKLAEAQQKAMLKGEAFPDIPMtlyEAIVRDYTGRTPE 998
Cdd:TIGR02768 492 -----AER----IGYAELETIRRQREAWARQASLELARGDVEKALAAYRDHGHITIHDTREEAI---EQVVADWKQDLRE 559
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 431482973 999 AREQ--TLIVTHLNEDRRVLNSMIHDAREKAGELGkEQVMVPVLNTA-NIRDGElrRLSTWENNPD 1061
Cdd:TIGR02768 560 ANPAgsQIMLAHTRKDVRALNEAAREALIERGELG-ESILFQTARGErKFAAGD--RIVFLENNRD 622
|
|
| PRK13826 |
PRK13826 |
Dtr system oriT relaxase; Provisional |
841-1031 |
4.33e-05 |
|
Dtr system oriT relaxase; Provisional
Pssm-ID: 237524 [Multi-domain] Cd Length: 1102 Bit Score: 47.85 E-value: 4.33e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 841 TLFLLDESSMVGNTDMARAYALIAAGGGRAVASGDTDQLQAIAPGQPFrlqqtRSAADVVIMKE---IVRQTPE-LREAV 916
Cdd:PRK13826 470 TVFVLDEAGMVASRQMALFVEAVTRAGAKLVLVGDPEQLQPIEAGAAF-----RAIADRIGYAEletIYRQREQwMRDAS 544
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 917 YSLINRDVERALSglesvkpsqvprqegawapehsvtefSHSQEAKLAEAQqkamLKGEAFPdipmTLYEAIVRDYtgrt 996
Cdd:PRK13826 545 LDLARGNVGKALD--------------------------AYRANGRVIGSR----LKAEAVE----SLIADWNRDY---- 586
|
170 180 190
....*....|....*....|....*....|....*
gi 431482973 997 pEAREQTLIVTHLNEDRRVLNSMihdAREKAGELG 1031
Cdd:PRK13826 587 -DPTKTTLILAHLRRDVRMLNEM---ARAKLVERG 617
|
|
| PRK13709 |
PRK13709 |
conjugal transfer nickase/helicase TraI; Provisional |
598-746 |
5.72e-04 |
|
conjugal transfer nickase/helicase TraI; Provisional
Pssm-ID: 237478 [Multi-domain] Cd Length: 1747 Bit Score: 44.40 E-value: 5.72e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 598 VAQVSGVREQaiLTEAIRSELKTQGVLGHPEVTMTALSPVwlDSRSRYLRDMyrpgmvmEQWNPETRS----HDRYV-ID 672
Cdd:PRK13709 1226 ITHLNEDRRV--LNSMIHDAREKAGELGKEQVTVPVLDTA--NIRDGELRRL-------STWEAHRGAlalvDNVYHrIA 1294
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 431482973 673 RVTAQSHSLTLRDAQGETQVVRISSLDSS-WSLFRPEKMPVADGERLRVTGKIPGLRVSGGDRLQVASVSEDAMT 746
Cdd:PRK13709 1295 GIDKDDGLITLRDAEGNTRLISPREAVAEgVTLYTPDTIRVGTGDRMRFTKSDRERGYVANSVWTVTAVSGDSVT 1369
|
|
| TraI_TIGR |
TIGR02760 |
conjugative transfer relaxase protein TraI; This protein is a component of the relaxosome ... |
985-1051 |
6.79e-04 |
|
conjugative transfer relaxase protein TraI; This protein is a component of the relaxosome complex. In the process of conjugative plasmid transfer the realaxosome binds to the plasmid at the oriT (origin of transfer) site. The relaxase protein TraI mediates the single-strand nicking and ATP-dependent unwinding (relaxation, helicase activity) of the plasmid molecule. These two activities reside in separate domains of the protein.
Pssm-ID: 274285 [Multi-domain] Cd Length: 1960 Bit Score: 44.12 E-value: 6.79e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 431482973 985 YEAIVRDYTGRTPEaREQTLIVTHLNEDRRVLNSMIHDAREKAGELGKEQVMVPVLNTANIRDGELR 1051
Cdd:TIGR02760 612 VDYIASAWLDLTPD-RQNSQVLATTHREQQDLTQIIRNALKQEGQLSRQEVTVPTLKPVNLTGIQRR 677
|
|
| PRK13889 |
PRK13889 |
conjugal transfer relaxase TraA; Provisional |
845-1039 |
1.35e-03 |
|
conjugal transfer relaxase TraA; Provisional
Pssm-ID: 237546 [Multi-domain] Cd Length: 988 Bit Score: 42.75 E-value: 1.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 845 LDESSMVGNTDMARAYALIAAGGGRAVASGDTDQLQAIAPGQPFRLQQTRSAAdvVIMKEIVRQTPE-LREAVYSLINRD 923
Cdd:PRK13889 439 IDEAGMVGTRQLERVLSHAADAGAKVVLVGDPQQLQAIEAGAAFRSIHERHGG--AEIGEVRRQREDwQRDATRDLATGR 516
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482973 924 VERALsglesvkpsqvprqegawapeHSVTEFSHSQEAKLAEAQQKAmlkgeafpdipmtLYEAIVRDytgRTPEAREQT 1003
Cdd:PRK13889 517 TGEAL---------------------DAYEAHGMVHAAATREQARAD-------------LIDRWDRD---RQAAPDRSR 559
|
170 180 190
....*....|....*....|....*....|....*.
gi 431482973 1004 LIVTHLNEDRRVLNSMIHDAREKAGELGkEQVMVPV 1039
Cdd:PRK13889 560 IILTHTNDEVRALNEAARERMRAAGDLG-DDVRVTV 594
|
|
| |
