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Conserved domains on  [gi|431482963|gb|ELH62664|]
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hypothetical protein A15E_00686 [Escherichia coli KTE202]

Protein Classification

MerC domain-containing protein( domain architecture ID 10014403)

MerC domain-containing protein similar to Acidithiobacillus ferrooxidans mercuric resistance protein MerC, an inner membrane protein that mediates mercury transport into the cytoplasm

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK13755 PRK13755
organomercurial transporter MerC;
1-139 1.22e-74

organomercurial transporter MerC;


:

Pssm-ID: 237490  Cd Length: 139  Bit Score: 218.39  E-value: 1.22e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482963   1 MGLMTRIADKTGALGSVVSAMGCAACFPALASFGAAIGLGFLSQYEGLFISRLLPLFAALAFLANALGWFSHRQWLRSLL 80
Cdd:PRK13755   1 MGLITRIADKTGALGSVVSAMGCAACFPALASLGAAIGLGFLSQYEGLFISTLLPLFAAIALLANALGWFSHRQWLRSAL 80

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 431482963  81 GMIGPAIVFAATVWLLGNWWTANLMYVGLALMIGVSIWDFVSPAHRRCGPDGCELPAKR 139
Cdd:PRK13755  81 GMIGPALVLAAVFLLLGNGWSANLLYVGLALMVGVSIWDFVSPAHRRCGPDSCELPAKR 139
 
Name Accession Description Interval E-value
PRK13755 PRK13755
organomercurial transporter MerC;
1-139 1.22e-74

organomercurial transporter MerC;


Pssm-ID: 237490  Cd Length: 139  Bit Score: 218.39  E-value: 1.22e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482963   1 MGLMTRIADKTGALGSVVSAMGCAACFPALASFGAAIGLGFLSQYEGLFISRLLPLFAALAFLANALGWFSHRQWLRSLL 80
Cdd:PRK13755   1 MGLITRIADKTGALGSVVSAMGCAACFPALASLGAAIGLGFLSQYEGLFISTLLPLFAAIALLANALGWFSHRQWLRSAL 80

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 431482963  81 GMIGPAIVFAATVWLLGNWWTANLMYVGLALMIGVSIWDFVSPAHRRCGPDGCELPAKR 139
Cdd:PRK13755  81 GMIGPALVLAAVFLLLGNGWSANLLYVGLALMVGVSIWDFVSPAHRRCGPDSCELPAKR 139
MerC pfam03203
MerC mercury resistance protein;
11-119 1.35e-11

MerC mercury resistance protein;


Pssm-ID: 427195  Cd Length: 105  Bit Score: 57.25  E-value: 1.35e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482963   11 TGALGSVVSAMGCAAcFPALASFGAAIGLGFLSqyEGLFISRLLPLFAALAFLANALGWFSHRQWLRSLLGMIGPAIVFA 90
Cdd:pfam03203   1 LGILLSLLCAIHCLA-LPLLLALLPALGLGFLE--EPLFHRLLLALFALIALLALGLGYRRHRRWLPLVLGLLGLALLFL 77

                          90       100
                  ....*....|....*....|....*....
gi 431482963   91 AtVWLLGNWWTANLMYVGLALMIGVSIWD 119
Cdd:pfam03203  78 A-LFLGGEAIEVVLTYIGSALLAAAHVLN 105
 
Name Accession Description Interval E-value
PRK13755 PRK13755
organomercurial transporter MerC;
1-139 1.22e-74

organomercurial transporter MerC;


Pssm-ID: 237490  Cd Length: 139  Bit Score: 218.39  E-value: 1.22e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482963   1 MGLMTRIADKTGALGSVVSAMGCAACFPALASFGAAIGLGFLSQYEGLFISRLLPLFAALAFLANALGWFSHRQWLRSLL 80
Cdd:PRK13755   1 MGLITRIADKTGALGSVVSAMGCAACFPALASLGAAIGLGFLSQYEGLFISTLLPLFAAIALLANALGWFSHRQWLRSAL 80

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 431482963  81 GMIGPAIVFAATVWLLGNWWTANLMYVGLALMIGVSIWDFVSPAHRRCGPDGCELPAKR 139
Cdd:PRK13755  81 GMIGPALVLAAVFLLLGNGWSANLLYVGLALMVGVSIWDFVSPAHRRCGPDSCELPAKR 139
MerC pfam03203
MerC mercury resistance protein;
11-119 1.35e-11

MerC mercury resistance protein;


Pssm-ID: 427195  Cd Length: 105  Bit Score: 57.25  E-value: 1.35e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 431482963   11 TGALGSVVSAMGCAAcFPALASFGAAIGLGFLSqyEGLFISRLLPLFAALAFLANALGWFSHRQWLRSLLGMIGPAIVFA 90
Cdd:pfam03203   1 LGILLSLLCAIHCLA-LPLLLALLPALGLGFLE--EPLFHRLLLALFALIALLALGLGYRRHRRWLPLVLGLLGLALLFL 77

                          90       100
                  ....*....|....*....|....*....
gi 431482963   91 AtVWLLGNWWTANLMYVGLALMIGVSIWD 119
Cdd:pfam03203  78 A-LFLGGEAIEVVLTYIGSALLAAAHVLN 105
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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