NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|42741652|ref|NP_976219|]
View 

SERTA domain-containing protein 3 [Homo sapiens]

Protein Classification

SERTA domain-containing protein( domain architecture ID 10532710)

SERTA domain-containing protein similar to Homo sapiens cell division cycle associated 4 (CDCA4) that may participate in the regulation of cell proliferation through the E2F/RB pathway

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
SERTA pfam06031
SERTA motif; This family consists of a novel motif designated as SERTA (for SEI-1, RBT1, and ...
 33-66 1.52e-11

SERTA motif; This family consists of a novel motif designated as SERTA (for SEI-1, RBT1, and TARA), corresponding to the largest conserved region among TRIP-Br proteins. The function of this motif is uncertain, but the CDK4-interacting segment of p34SEI-1 (amino acid residues 44-161) includes most of the SERTA motif.


:

Pssm-ID: 461806  Cd Length: 36  Bit Score: 56.40  E-value: 1.52e-11
                          10        20        30
                  ....*....|....*....|....*....|....
gi 42741652    33 LLRISLDKVQRSLGPRAPSLRRHVLIHNTLQQLQ 66
Cdd:pfam06031   1 VLNLSLDKLQRSRDLVEPSLRRSVLINNTLRRIQ 34
 
Name Accession Description Interval E-value
SERTA pfam06031
SERTA motif; This family consists of a novel motif designated as SERTA (for SEI-1, RBT1, and ...
 33-66 1.52e-11

SERTA motif; This family consists of a novel motif designated as SERTA (for SEI-1, RBT1, and TARA), corresponding to the largest conserved region among TRIP-Br proteins. The function of this motif is uncertain, but the CDK4-interacting segment of p34SEI-1 (amino acid residues 44-161) includes most of the SERTA motif.


Pssm-ID: 461806  Cd Length: 36  Bit Score: 56.40  E-value: 1.52e-11
                          10        20        30
                  ....*....|....*....|....*....|....
gi 42741652    33 LLRISLDKVQRSLGPRAPSLRRHVLIHNTLQQLQ 66
Cdd:pfam06031   1 VLNLSLDKLQRSRDLVEPSLRRSVLINNTLRRIQ 34
 
Name Accession Description Interval E-value
SERTA pfam06031
SERTA motif; This family consists of a novel motif designated as SERTA (for SEI-1, RBT1, and ...
 33-66 1.52e-11

SERTA motif; This family consists of a novel motif designated as SERTA (for SEI-1, RBT1, and TARA), corresponding to the largest conserved region among TRIP-Br proteins. The function of this motif is uncertain, but the CDK4-interacting segment of p34SEI-1 (amino acid residues 44-161) includes most of the SERTA motif.


Pssm-ID: 461806  Cd Length: 36  Bit Score: 56.40  E-value: 1.52e-11
                          10        20        30
                  ....*....|....*....|....*....|....
gi 42741652    33 LLRISLDKVQRSLGPRAPSLRRHVLIHNTLQQLQ 66
Cdd:pfam06031   1 VLNLSLDKLQRSRDLVEPSLRRSVLINNTLRRIQ 34
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH