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Conserved domains on  [gi|426405877|ref|YP_007024970|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Apodemus latronum]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475899)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-345 2.96e-152

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 431.58  E-value: 2.96e-152
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877   1 MNPITLIIIYSTIFLGPIITMLSSNLLLMWVGLEFSLLAITPLLIDKKNPRSTEAATKYFVTQATASMMILLAIVLNYKQ 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  81 LGLWTFHQQTNFITLNLTLIALSMKLGLAPFHFWLPEVTQGIKLHTGLLLLTWQKIAPLSILFQIYNLLDHTMILLMATL 160
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877 161 SIFMGAWGGLNQTQMRKIMAYSSIAHMGWMLAILPYNPTMTLLNLTIYILLTIPMFILLILNSSTTINSMSLLWNKTPTI 240
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877 241 LTIIPLILLSLGGLPPLTGFLPKWAIITELLKNNCLILTTLMAMMALLNLFFYTRLIYSSTLTMFPTNNNSKMLTHHTNY 320
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                        330       340
                 ....*....|....*....|....*
gi 426405877 321 KHNIILPSLTVMSTLILPLSPQLII 345
Cdd:MTH00105 321 KPMTLLPTLIILSTMLLPLTPMLSI 345
 
Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-345 2.96e-152

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 431.58  E-value: 2.96e-152
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877   1 MNPITLIIIYSTIFLGPIITMLSSNLLLMWVGLEFSLLAITPLLIDKKNPRSTEAATKYFVTQATASMMILLAIVLNYKQ 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  81 LGLWTFHQQTNFITLNLTLIALSMKLGLAPFHFWLPEVTQGIKLHTGLLLLTWQKIAPLSILFQIYNLLDHTMILLMATL 160
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877 161 SIFMGAWGGLNQTQMRKIMAYSSIAHMGWMLAILPYNPTMTLLNLTIYILLTIPMFILLILNSSTTINSMSLLWNKTPTI 240
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877 241 LTIIPLILLSLGGLPPLTGFLPKWAIITELLKNNCLILTTLMAMMALLNLFFYTRLIYSSTLTMFPTNNNSKMLTHHTNY 320
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                        330       340
                 ....*....|....*....|....*
gi 426405877 321 KHNIILPSLTVMSTLILPLSPQLII 345
Cdd:MTH00105 321 KPMTLLPTLIILSTMLLPLTPMLSI 345
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-268 7.05e-23

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 96.61  E-value: 7.05e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877   23 SSNLLLMWVGLEFSLLAITPLLID-KKNPRSTEAATKYFVTQATASMMILLAIVLNYKQLGLWTFHQQTNFITLN----- 96
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGYwGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTGGlnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877   97 ------LTLIALSMKLGLAPFHFWLPEVTQGIKLHTGLLLL-TWQKIAPLSI-----LFQIYNLLDHTMILLMATLSIFM 164
Cdd:pfam00361  81 llllflLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAaTLVKAGGYGLirrslLYLPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  165 GAWGGLNQTQMRKIMAYSSIAHMGWMLAIL----PYNPTMTLLNLTIYILLTIPMF-----ILLILNSSTTINSMSLLWN 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFlcagsVIYRRVHTRNIRDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 426405877  236 KTPTILTIIPLILLSLGGLPPLTGFLPKWAIIT 268
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 23-298 3.13e-22

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 97.11  E-value: 3.13e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  23 SSNLLLMWVGLE---FSLLAITPLliDKKNPRSTEAATKYFVTQATASMMILLAIVLNYKQLGLWTFHQQTNFITLN--- 96
Cdd:COG1007  121 ANDLLTLFLGLEllsLSLYVLVAF--RRDDRRSSEAALKYFLLGALSSGFLLYGISLLYGATGSLNLAGIAAALAAGgan 198

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  97 ---------LTLIALSMKLGLAPFHFWLPEVTQGIKLHTGLLLLTWQKIAPLSILFQIYNLLDH-------TMILLMATL 160
Cdd:COG1007  199 spllllglvLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLRLLVEAFPglaadwqLLLAVLAVL 278

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877 161 SIFMGAWGGLNQTQMRKIMAYSSIAHMGWMLAILPYNPTM----TLLNLTIYILLTIPMFILLILNS-----STTINSMS 231
Cdd:COG1007  279 SMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLgvsaALFYLLAYLFMNLGAFAVILLLSrkggeAEEIEDLA 358

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 426405877 232 LLWNKTPTILTIIPLILLSLGGLPPLTGFLPKWAIITELLKNNCLILTTLMAMMALLNLFFYTRLIY 298
Cdd:COG1007  359 GLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRVVK 425
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 6-345 1.71e-20

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 91.93  E-value: 1.71e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877    6 LIIIYSTIFLGPIITMLSSNLLLMWVGLEFSLLAITPLL-IDKKNPRSTEAATKYFVTQATASMMILLAIVLNYKQLGLW 84
Cdd:TIGR01770 104 FYILLLFALLGIFLLVSSNDLLSIYLGLELQSLCFYVLAgLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSL 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877   85 TFHQQTNFITLN------------LTLIALSMKLGLAPFHFWLPEVTQGIKLHTGLLLLTWQKIAPLSILFQIYNLLD-- 150
Cdd:TIGR01770 184 NFEDLLLFLSNGmlnisllllgivLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYILfg 263

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  151 -----HTMILLMATLSIFMGAWGGLNQTQMRKIMAYSSIAHMGWMLAILPYNPTM----TLLNLTIYILLTIPMFILLIL 221
Cdd:TIGR01770 264 fseawQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEgikaVLFYIFIYALMSLGAFGVLSL 343

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  222 NSST------TINSMSLLWNKTPTILTIIPLILLSLGGLPPLTGFLPKWAIITELLKNNCLILTTLMAMMALLNLFFYTR 295
Cdd:TIGR01770 344 LRSYkdewieYISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLR 423

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|
gi 426405877  296 LIYSstltMFPTNNNSKMLTHHTNYKHNIILpSLTVMSTLILPLSPQLII 345
Cdd:TIGR01770 424 VVKV----MYFDKPERRIPSNPQSKAQSLLL-SISALFILFLGLFPSLIL 468
 
Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-345 2.96e-152

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 431.58  E-value: 2.96e-152
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877   1 MNPITLIIIYSTIFLGPIITMLSSNLLLMWVGLEFSLLAITPLLIDKKNPRSTEAATKYFVTQATASMMILLAIVLNYKQ 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  81 LGLWTFHQQTNFITLNLTLIALSMKLGLAPFHFWLPEVTQGIKLHTGLLLLTWQKIAPLSILFQIYNLLDHTMILLMATL 160
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877 161 SIFMGAWGGLNQTQMRKIMAYSSIAHMGWMLAILPYNPTMTLLNLTIYILLTIPMFILLILNSSTTINSMSLLWNKTPTI 240
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877 241 LTIIPLILLSLGGLPPLTGFLPKWAIITELLKNNCLILTTLMAMMALLNLFFYTRLIYSSTLTMFPTNNNSKMLTHHTNY 320
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                        330       340
                 ....*....|....*....|....*
gi 426405877 321 KHNIILPSLTVMSTLILPLSPQLII 345
Cdd:MTH00105 321 KPMTLLPTLIILSTMLLPLTPMLSI 345
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-344 4.72e-103

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 306.75  E-value: 4.72e-103
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877   1 MNPITLIIIYSTIFLGPIITMLSSNLLLMWVGLEFSLLAITPLLIDKKNPRSTEAATKYFVTQATASMMILLAIVLNYKQ 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  81 LGLWTFHQQTNFITLNLTLIALSMKLGLAPFHFWLPEVTQGIKLHTGLLLLTWQKIAPLSILFQIYNLLDHTMILLMATL 160
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877 161 SIFMGAWGGLNQTQMRKIMAYSSIAHMGWMLAILPYNPTMTLLNLTIYILLTIPMFILLILNSSTTINSMSLLWNKTPTI 240
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877 241 LTIIPLILLSLGGLPPLTGFLPKWAIITELLKNNCLILTTLMAMMALLNLFFYTRLIYSSTLTMFPTNNNSKMLTHHTNY 320
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                        330       340
                 ....*....|....*....|....
gi 426405877 321 KHNIIlPSLTVMSTLILPLSPQLI 344
Cdd:MTH00112 321 KNTLT-ATLTTLSTLLLPLSPMIL 343
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-344 5.40e-102

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 304.03  E-value: 5.40e-102
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877   1 MNPITLIIIYSTIFLGPIITMLSSNLLLMWVGLEFSLLAITPLLIDKKNPRSTEAATKYFVTQATASMMILLAIVLNYKQ 80
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  81 LGLWTFHQQTNFITLNLTLIALSMKLGLAPFHFWLPEVTQGIKLHTGLLLLTWQKIAPLSILFQIYNLlDHTMILLMATL 160
Cdd:MTH00135  81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPT-NPTLLITLGLT 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877 161 SIFMGAWGGLNQTQMRKIMAYSSIAHMGWMLAILPYNPTMTLLNLTIYILLTIPMFILLILNSSTTINSMSLLWNKTPTI 240
Cdd:MTH00135 160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPAL 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877 241 LTIIPLILLSLGGLPPLTGFLPKWAIITELLKNNCLILTTLMAMMALLNLFFYTRLIYSSTLTMFPTNNNSKMLTHHTNY 320
Cdd:MTH00135 240 TALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPST 319

                        330       340
                 ....*....|....*....|....
gi 426405877 321 KHNIILPSLTVMSTLILPLSPQLI 344
Cdd:MTH00135 320 QLTLPLAISTTATLMLLPLTPAIL 343
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-344 5.12e-99

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 296.45  E-value: 5.12e-99
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877   1 MNPITLIIIYSTIFLGPIITMLSSNLLLMWVGLEFSLLAITPLLIDKKNPRSTEAATKYFVTQATASMMILLAIVLNYKQ 80
Cdd:MTH00070   1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  81 LGLWTFHQQTNFITLNLTLIALSMKLGLAPFHFWLPEVTQGIKLHTGLLLLTWQKIAPLSILFQIYNLLDHTMILLMATL 160
Cdd:MTH00070  81 TGEWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877 161 SIFMGAWGGLNQTQMRKIMAYSSIAHMGWMLAILPYNPTMTLLNLTIYILLTIPMFILLILNSSTTINSMSLLWNKTPTI 240
Cdd:MTH00070 161 STLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877 241 LTIIPLILLSLGGLPPLTGFLPKWAIITELLKNNCLILTTLMAMMALLNLFFYTRLIYSSTLTMFPTNNNSKMLTHHTNY 320
Cdd:MTH00070 241 TSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRFKNK 320

                        330       340
                 ....*....|....*....|....
gi 426405877 321 KHNiILPSLTVMSTLILPLSPQLI 344
Cdd:MTH00070 321 TNN-LLSLTIILSLMLLPITPTIL 343
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-344 6.36e-80

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 247.57  E-value: 6.36e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877   1 MNPITLIIIYSTIFLGPIITMLSSNLLLMWVGLEFSLLAITPLLIDKKNPRSTEAATKYFVTQATASMMILLAIVLNYKQ 80
Cdd:MTH00200   1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  81 LGLWTFHQQTNFITLNLTLIALSMKLGLAPFHFWLPEVTQGIKLHTGLLLLTWQKIAPLSILFQIYNLLDHTMILLMATL 160
Cdd:MTH00200  81 SGQWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877 161 SIFMGAWGGLNQTQMRKIMAYSSIAHMGWMLAILPYNPTMTLLNLTIYILLTIPMFILLILNSSTTINSMSLLWNKTPTI 240
Cdd:MTH00200 161 SVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPIL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877 241 LTIIPLILLSLGGLPPLTGFLPKWAIITELLKNNCLILTTLMAMMALLNLFFYTRLIYSSTLTMFPTNNNSkMLTHHTNY 320
Cdd:MTH00200 241 SMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINM-MSSWRTKS 319

                        330       340
                 ....*....|....*....|....
gi 426405877 321 KHNIILPSLTVMSTLILPLSPQLI 344
Cdd:MTH00200 320 NSNLLVGLLLLLSILGLPLTPQLL 343
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 1-339 4.00e-71

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 225.19  E-value: 4.00e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877   1 MNPITLIIIYSTIFLGPIITMLSSNLLLMWVGLEFSLLAITPLLIDKKNPRSTEAATKYFVTQATASMMILLAIVLNYKQ 80
Cdd:MTH00041   1 MNRNVLIFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  81 LGLWTFHQQTNFITLNLTLIALSMKLGLAPFHFWLPEVTQGIKLHTGLLLLTWQKIAPLSILFQIYNLLDHTMILLMATL 160
Cdd:MTH00041  81 SGSWSINGPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877 161 SIFMGAWGGLNQTQMRKIMAYSSIAHMGWMLAILPYNPTMTLLNLTIYILLTIPMFILLILNSSTTINSMSLLWNKTPTI 240
Cdd:MTH00041 161 SVLVGGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPIS 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877 241 LTIIPLILLSLGGLPPLTGFLPKWAIITELLKNNCLILTTLMAMMALLNLFFYTRLIYSSTLTMFPTN----NNSKMLTH 316
Cdd:MTH00041 241 AFLFILSILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHsislFSWRNSGN 320

                        330       340
                 ....*....|....*....|....
gi 426405877 317 HTNYKHNI-ILPSLTVMSTLILPL 339
Cdd:MTH00041 321 ITVYGVILsILSSISILGLLLIPL 344
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-339 2.01e-49

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 168.46  E-value: 2.01e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877   1 MNPITLIIIYSTIFLGPIITMLSSNLLLMWVGLEFSLLAITPLLIDKKNPRSTEAATKYFVTQATASMMILLAIVLNYKQ 80
Cdd:MTH00160   2 MMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNMLN 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  81 LGLwtfhqqTNFITLNLTLIALSMKLGLAPFHFWLPEVTQGIKLHTGLLLLTWQKIAPLSILFQIYNlldHTMILLMATL 160
Cdd:MTH00160  82 LML------FNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLIN---NNFIIIIIIL 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877 161 SIFMGAWGGLNQTQMRKIMAYSSIAHMGWMLAILPYNPTMTLLNLTIYILLTIPMFILLILNSSTTINSMSLLWNKTPTI 240
Cdd:MTH00160 153 SAIIGAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKI 232

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877 241 LTIIPLILLSLGGLPPLTGFLPKWAIITELLKNNCLILTTLMAMMALLNLFFYTRLIYSSTLTMFPTNNNSKMLTHHTNY 320
Cdd:MTH00160 233 KFLLFLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFS 312

                        330
                 ....*....|....*....
gi 426405877 321 KHNIILPSLTVMSTLILPL 339
Cdd:MTH00160 313 LILNFLSFISLFGLILSSL 331
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 13-337 1.10e-46

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 161.21  E-value: 1.10e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  13 IFLGPIITMLSSNLLLMWVGLEFSLLAITPLLIDKKNPRSTEAATKYFVTQATASMMILLAIVLNYKQLGLWtfhqqtnf 92
Cdd:MTH00144  13 MVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSW-------- 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  93 ITLNLTLIALSMKLGLAPFHFWLPEVTQGIKLHTGLLLLTWQKIAPLSILFQIYNLLDHTMIL-LMATLSIFMGAWGGLN 171
Cdd:MTH00144  85 FSMSLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLAYLLcVISVLSALVGSIGGLN 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877 172 QTQMRKIMAYSSIAHMGWMLAILPYNPTMTLLNLTIYILLTIPMFILLILNSSTTINSMSLLwNKTPTILTIIPLILLSL 251
Cdd:MTH00144 165 QTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDLGSL-KPSYKTGLSIISLLLSL 243

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877 252 GGLPPLTGFLPKWAIITELLKNNCLILTTLMAMMALLNLFFYTRLIYSSTLTMFptnnnsKMLTHHTNYKHNIILPSLTV 331
Cdd:MTH00144 244 GGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSS------KSKKSNSSKVLNSSIISLNL 317


                 ....*.
gi 426405877 332 MSTLIL 337
Cdd:MTH00144 318 LGGLLF 323
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 5-304 1.51e-44

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 155.71  E-value: 1.51e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877   5 TLIIIYSTIFLGPIITMLSSNLLLMWVGLEFSLLAITPLLIDKKNPRSTEAATKYFVTQATASMMILLAIVLnykqlgLW 84
Cdd:MTH00011   7 TMFLFSSTMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTM------MW 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  85 TFHQQTNFITLNLTLIALSMKLGLAPFHFWLPEVTQGIKLHTGLLLLTWQKIAPLSILFQIYNLLDHTMILLMATLSIFM 164
Cdd:MTH00011  81 SFPSLLKNITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAMSALA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877 165 GAWGGLNQTQMRKIMAYSSIAHMGWMLAILPYNPTMTLLNLTIYILLTIPMFILLILNSSTTINSMSLLWNKTPTILTII 244
Cdd:MTH00011 161 GGLGGMNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSL 240

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877 245 PLILLSLGGLPPLTGFLPKWAIITELLKNNCLILTTLMAMMALLNLFFYTRLIYSSTLTM 304
Cdd:MTH00011 241 FIMLLSLGGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFNFMYLS 300
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 8-315 7.28e-38

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 137.88  E-value: 7.28e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877   8 IIYSTIFLGPIITMLSSNLLLMWVGLEFSLLAITPLLIDKKNPRSTEAATKYFVTQATASMMILLAIVLNYKQLGLWTFH 87
Cdd:MTH00197   2 LFLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLSFSNLYLSLLS 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  88 QQtnfitlnLTLIALSMKLGLAPFHFWLPEVTQGIKLHTGLLLLTWQKIAPLSILFQIYNLLDhtMILLMATLSIFMGAW 167
Cdd:MTH00197  82 VV-------LVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFNSSSFM--GLLICSVLSSLIGGI 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877 168 GGLNQTQMRKIMAYSSIAHMGWMLAILPYNPTMTLLNLTIYILLTIPMFILLILNSSTTINSMSLLWNKTPTILTIIPLI 247
Cdd:MTH00197 153 GGMNQSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLS 232

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 426405877 248 LLSLGGLPPLTGFLPKWAIITELLKNNCLILTTLMAMMALLNLFFYTRLIYSSTLTMFPTNNNSKMLT 315
Cdd:MTH00197 233 FLSLGGLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKSLILSNWMINFLMKIN 300
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-268 7.05e-23

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 96.61  E-value: 7.05e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877   23 SSNLLLMWVGLEFSLLAITPLLID-KKNPRSTEAATKYFVTQATASMMILLAIVLNYKQLGLWTFHQQTNFITLN----- 96
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGYwGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTGGlnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877   97 ------LTLIALSMKLGLAPFHFWLPEVTQGIKLHTGLLLL-TWQKIAPLSI-----LFQIYNLLDHTMILLMATLSIFM 164
Cdd:pfam00361  81 llllflLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAaTLVKAGGYGLirrslLYLPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  165 GAWGGLNQTQMRKIMAYSSIAHMGWMLAIL----PYNPTMTLLNLTIYILLTIPMF-----ILLILNSSTTINSMSLLWN 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFlcagsVIYRRVHTRNIRDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 426405877  236 KTPTILTIIPLILLSLGGLPPLTGFLPKWAIIT 268
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 23-298 3.13e-22

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 97.11  E-value: 3.13e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  23 SSNLLLMWVGLE---FSLLAITPLliDKKNPRSTEAATKYFVTQATASMMILLAIVLNYKQLGLWTFHQQTNFITLN--- 96
Cdd:COG1007  121 ANDLLTLFLGLEllsLSLYVLVAF--RRDDRRSSEAALKYFLLGALSSGFLLYGISLLYGATGSLNLAGIAAALAAGgan 198

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  97 ---------LTLIALSMKLGLAPFHFWLPEVTQGIKLHTGLLLLTWQKIAPLSILFQIYNLLDH-------TMILLMATL 160
Cdd:COG1007  199 spllllglvLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLRLLVEAFPglaadwqLLLAVLAVL 278

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877 161 SIFMGAWGGLNQTQMRKIMAYSSIAHMGWMLAILPYNPTM----TLLNLTIYILLTIPMFILLILNS-----STTINSMS 231
Cdd:COG1007  279 SMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLgvsaALFYLLAYLFMNLGAFAVILLLSrkggeAEEIEDLA 358

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 426405877 232 LLWNKTPTILTIIPLILLSLGGLPPLTGFLPKWAIITELLKNNCLILTTLMAMMALLNLFFYTRLIY 298
Cdd:COG1007  359 GLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRVVK 425
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 4-298 4.98e-22

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 96.24  E-value: 4.98e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877   4 ITLIIIystIFLGPIITMLSSNLLLMWVGLEFSLLAITPLLIDKKNP-RSTEAATKYFVTQATASMMILLAIVLNYKQLG 82
Cdd:MTH00199 100 PILILI---VALGSLLLVSSINWLSIYLAIELQTLTLFILVALKRDSaYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTG 176

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  83 LWTFhQQTNFITLN-----LTLIALSMKLGLAPFHFWLPEVTQGIKLHTGLLLLTWQKIAPLSILFQIYNLLDhtMILLM 157
Cdd:MTH00199 177 ETSI-QGINSILTGdvgkiLITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTN--VVLIC 253

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877 158 ATLSIFMGAWGGLNQTQMRKIMAYSSIAHMGWMLAILPYNP----TMTLLNLTIYILLTIPMF-ILLILN-SSTTINSMS 231
Cdd:MTH00199 254 AVLSIIYGAIGALNQTKIKRLLAYSGIGHMGFILFGVAIGSfesiQASLIYMIIYVIMSICSFsIILSLKlTKGLIVEVS 333

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 426405877 232 LLWNKTPTILTIIPLILLSLGGLPPLTGFLPKWAIITELLKNNCLILTTLMAMMALLNLFFYTRLIY 298
Cdd:MTH00199 334 GLSRKNPVIALTLALTFLSIAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRVVQ 400
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
15-224 9.02e-21

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 92.96  E-value: 9.02e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  15 LGPIITMLSSNLLLMWVGLEFSLLAITPLL-IDKKNPRSTEAATKYFVTQATASMMILLAIVLNY------------KQL 81
Cdd:PRK05777 114 LGMMVMVSANDLLTLFLGLELLSLPLYALAaLRRDRRRSLEAAIKYFVLGALASGFLLYGMSLLYgatgslsfagiaKAL 193

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  82 GLWTFHQQTNFITLNLTLIALSMKLGLAPFHFWLPEVTQGIKLHTGLLLLTWQKIAPLSILFQIYNLLD-------HTMI 154
Cdd:PRK05777 194 ADGSGNSLLLLFGLVFLLVGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAVLLRLLVVAFgglsedwQQVL 273

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 426405877 155 LLMATLSIFMGAWGGLNQTQMRKIMAYSSIAHMGWML-AILPYNPTM---TLLNLTIYILLTIPMFILLILNSS 224
Cdd:PRK05777 274 AIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLvGLAAGTAEGysaVLFYLLAYLFMTLGAFGVISLLRR 347
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 13-297 1.10e-20

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 91.63  E-value: 1.10e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  13 IFLGPIITMLSSNLLLMWVGLEFSLLAITPLLIDKKNP-RSTEAATKYFVTQATASMMILLAIVLNYKQLGLWTFhQQTN 91
Cdd:MTH00196   2 VALGILCLISSSNWLSVYLAIELQTLSLFILIAQNRGSgYSAEAGLKYFVLGALSSGLFLFGCALLCGTTGGLHL-SYIN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  92 FITLN--------------LTLIALSMKLGLAPFHFWLPEVTQGIKLHTGLLLLTWQKIAPLSILFQIYNlldHTMILLM 157
Cdd:MTH00196  81 LVLNSgqsfssvsvpigylLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGL---NVNILLI 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877 158 ATL-SIFMGAWGGLNQTQMRKIMAYSSIAHMGWMLAILPYNP----TMTLLNLTIYILLTIPMF-ILLILNSSTT-INSM 230
Cdd:MTH00196 158 GGLfSLFVGAIGALNQTKIKRLLAYSGIGHMGFVLWGIEIGSfesiQASLVYLFIYIIMSICVFsIILALNVYKNlIIEF 237

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 426405877 231 SLLWNKTPTILTIIPLILLSLGGLPPLTGFLPKWAIITELLKNNCLILTTLMAMMALLNLFFYTRLI 297
Cdd:MTH00196 238 SGLSRRLPILAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRIV 304
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 6-345 1.71e-20

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 91.93  E-value: 1.71e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877    6 LIIIYSTIFLGPIITMLSSNLLLMWVGLEFSLLAITPLL-IDKKNPRSTEAATKYFVTQATASMMILLAIVLNYKQLGLW 84
Cdd:TIGR01770 104 FYILLLFALLGIFLLVSSNDLLSIYLGLELQSLCFYVLAgLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSL 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877   85 TFHQQTNFITLN------------LTLIALSMKLGLAPFHFWLPEVTQGIKLHTGLLLLTWQKIAPLSILFQIYNLLD-- 150
Cdd:TIGR01770 184 NFEDLLLFLSNGmlnisllllgivLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYILfg 263

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  151 -----HTMILLMATLSIFMGAWGGLNQTQMRKIMAYSSIAHMGWMLAILPYNPTM----TLLNLTIYILLTIPMFILLIL 221
Cdd:TIGR01770 264 fseawQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEgikaVLFYIFIYALMSLGAFGVLSL 343

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  222 NSST------TINSMSLLWNKTPTILTIIPLILLSLGGLPPLTGFLPKWAIITELLKNNCLILTTLMAMMALLNLFFYTR 295
Cdd:TIGR01770 344 LRSYkdewieYISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLR 423

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|
gi 426405877  296 LIYSstltMFPTNNNSKMLTHHTNYKHNIILpSLTVMSTLILPLSPQLII 345
Cdd:TIGR01770 424 VVKV----MYFDKPERRIPSNPQSKAQSLLL-SISALFILFLGLFPSLIL 468
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 22-192 2.97e-16

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 79.04  E-value: 2.97e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  22 LSSNLLLMWVGLEFSLLAITPLLIDKKNPRSTEAATKYFVTQATASMMILLAIVLNYKQLGLWTFHQQTNFITLN----- 96
Cdd:COG0651  125 LTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNMADLAARLAELdpgll 204

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  97 -----LTLIALSMKLGLAPFHFWLPE-----------VTQGIKLHTGL--LLLTWQKIAPLSILFQIynlldHTMILLMA 158
Cdd:COG0651  205 laafaLLLVGFGIKAALFPLHFWLPDaypaapspvsaLLSGLLTKVGVyaILRVLTLLFGADPALFL-----GTLLLVLG 279

                        170       180       190
                 ....*....|....*....|....*....|....
gi 426405877 159 TLSIFMGAWGGLNQTQMRKIMAYSSIAHMGWMLA 192
Cdd:COG0651  280 LLTMLVGALGALAQRDLKRLLAYSSVSQIGYILL 313
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 22-192 3.62e-11

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 63.95  E-value: 3.62e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  22 LSSNLLLMWVGLEFSLLAITPLLIDKKNPRSTEAATKYFVTQATASMMILLAIVLNYKQLGLWTFhqqtNFITLN----- 96
Cdd:COG1008  129 LALDLFLFYVFWELMLIPMYFLIGIWGGERRIYAAIKFFLYTLAGSLLMLVAILALYFLAGALTF----DIAELAaaplp 204

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  97 ---------LTLIALSMKLGLAPFHFWLPEV-----TQGIKLHTGLLL----------------LTWQKIAPLsilfqiy 146
Cdd:COG1008  205 ltaqlllflAFFIAFAVKVPMFPFHTWLPDAhveapTAGSVLLAGVLLkmggygllrfalplfpEASAYFAPL------- 277

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 426405877 147 nlldhtmILLMATLSIFMGAWGGLNQTQMRKIMAYSSIAHMGWMLA 192
Cdd:COG1008  278 -------LAALGVIGIIYGALVALAQTDLKRLIAYSSVSHMGFVLL 316
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 5-191 3.63e-11

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 63.96  E-value: 3.63e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877   5 TLIIIYSTIFLGPIITmlsSNLLLMWVGLEFSLLAITPLLIDKKN-PRSTEAATKYFVTQATASMMILLAIVLNYKQLGL 83
Cdd:PRK08376 125 TLILLLELGMLGMAIT---GDLFNFFVFLEIMSIASYALVAFRNDtWEAIEAGIKYMFVGSLASSMVLLGIALLYGQYGT 201

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  84 WTFH----------QQTNFITLNLTLIALSMKLGLAPFHFWLP----EVTQGIklhTGLLLLTWQK--IAPLSILFQIYN 147
Cdd:PRK08376 202 LNMAylavkmsenpTVVAKIALALFIAGLAMKSGAVPVHMWLPdaypAAPSSI---SAMLLVIKQAglYALARVLFSIYG 278

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 426405877 148 LLDHT-----MILLMATLSIFMGAWGGLNQTQMRKIMAYSSIAHMGWML 191
Cdd:PRK08376 279 PAINLatvgwVIIILGCLTMFVGVAMAVVQKDVKRLLAYHSVSQIGYML 327
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 15-191 7.85e-11

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 62.95  E-value: 7.85e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  15 LGPIITMLSSNLLLMWVGLEFSLLAITPLLIDKKNPRST---------EAATKYFVTQATASMMILLAIVLNYKQLG--- 82
Cdd:MTH00198 199 LGGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGCALYFGFTGneg 278

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  83 -LWTFHQQTnFITLNLTL-----------IALSMKLGLAPFHFWLPEVTQGIKLHTGLLLLTWQKIAPLSILFQIynLLD 150
Cdd:MTH00198 279 mLGTILSAT-LETTNIELrqgslgylfitVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILLTSL--VIT 355

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 426405877 151 HTMILLMATLSIFMGAWGGLNQTQMRKIMAYSSIAHMGWML 191
Cdd:MTH00198 356 SKLLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFIL 396
ndhB CHL00049
NADH dehydrogenase subunit 2
 7-215 5.65e-10

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 60.40  E-value: 5.65e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877   7 IIIYSTIFLGPIITMLSSNLLLMWVGLEFSLLAITPLL-IDKKNPRSTEAATKYFVTQATASMMILLAIVLNYK----QL 81
Cdd:CHL00049 114 LLFVLTATLGGMFLCGANDLITIFVALECLSLCSYLLSgYTKKDVRSNEATMKYLLMGGASSSILVYGFSWLYGlsggEI 193

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  82 GLW------TFHQQTN----FITLNLTLIALSMKLGLAPFHFWLPEVTQGIKLHTGLLLLTWQKIAPLSILFQIYNLLD- 150
Cdd:CHL00049 194 ELQeivnglINTQMYNspgiSIALIFITVGIGFKLSLAPFHQWTPDVYEGSPTPVVAFLSVTSKVAASALATRIFDIPFy 273

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 426405877 151 ------HTMILLMATLSIFMGAWGGLNQTQMRKIMAYSSIAHMGW-MLAILPYNPTMTLLNLTIYILLTIPM 215
Cdd:CHL00049 274 fssnewHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYvIIGIIVGDSNDGYASMITYMLFYIFM 345
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 18-191 1.70e-09

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 58.80  E-value: 1.70e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877   18 IITMLSSNLLLMWVGLEFSLLAITPLLIDKKNPRSTEAATKYFVTQATASMMILLAIVLnYKQLGLWTFhQQTNFITLNL 97
Cdd:TIGR01972 120 IGVFLALDLFLFYVFWEAMLIPMYLLIGVWGGPNRIYAAMKFFLYTLAGSLLMLLAILG-LYFLGGGTF-DLLELLNLPL 197

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877   98 T-----------LIALSMKLGLAPFHFWLPEV-----TQGIKLHTGLLLltwqKIAPLSILFQIYNLLDHTM------IL 155
Cdd:TIGR01972 198 PfgvqtwlflafFIAFAVKVPLFPLHTWLPDAhveapTAGSVILAGVLL----KMGTYGFLRFNLPLFPDASlyfapvLA 273

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 426405877  156 LMATLSIFMGAWGGLNQTQMRKIMAYSSIAHMGWML 191
Cdd:TIGR01972 274 ALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVL 309
NADH_dehy_S2_C pfam06444
NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region ...
 291-341 7.44e-09

NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region specific to the eukaryotic NADH dehydrogenase subunit 2 protein and is found in conjunction with pfam00361.


Pssm-ID: 461914 [Multi-domain]  Cd Length: 51  Bit Score: 51.10  E-value: 7.44e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 426405877  291 FFYTRLIYSSTLTMFPTNNNSKMLTHHTNYKHNIILPSLTVMSTLILPLSP 341
Cdd:pfam06444   1 FFYLRLSYSTTLTLFPNTNNSKMKWRFNSTKNTLLLPTLTTLSILLLPLTP 51
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 21-298 8.65e-09

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 56.81  E-value: 8.65e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  21 MLSSNLLLMWVGLEFSLLAITPLLIDKKNPRSTEAATKYFVTQATASMMILLAIVLNYKQLGLWTF--------HQQTNF 92
Cdd:PRK08375 123 LLTADLFNLFVFLEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGVGLLYGVTGTLNMadlagalaENPTVV 202

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  93 ITLNLTLIALSMKLGLAPFHFWLPE--------VTQgikLHTGLLLltwqKIAPLS---ILFQIY------NLLDHTMIL 155
Cdd:PRK08375 203 TAFGFVLLALALKAAVFPLHTWLPRaypaappvVTA---LLSGLVT----KVAVYAlirIYFTVFggdfrfALGLGWLLA 275

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877 156 LMATLSIFMGAWGGLNQTQMRKIMAYSSIAHMGWMLAILPYNPTMTLLNLTIYILLTIPMFILLILNS--------STTI 227
Cdd:PRK08375 276 VLALLSMLVGSLAALGQDDVKRVLAYSTVSQMGYILLGLALLTPLALAAGLLHLLHHALMKGALFLAAgaievtygTRRL 355

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 426405877 228 NSMSLLWNKTPTILTIIPLILLSLGGLPPLTGFLPKWAIITELLKNNCLILTTLMAMMALLNLFFYTRLIY 298
Cdd:PRK08375 356 SELSGLGRRMPLTAAAFAVASLSLIGVPPTSGFVSKWYLVVGAVEAGQWLVLAVLLASSLLALLYFLRIWY 426
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
10-191 6.91e-08

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 53.94  E-value: 6.91e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  10 YSTIFL---GPIITMLSSNLLLMWVGLEFSLLAITPLLIDKKNPRSTEAATKYFVTQATASMMILLAIV----------L 76
Cdd:PRK06473 110 YSLLLLlnaGVSGAFLAQDLLLFFLFYELELIPLYLLIAIWGGQRRGYAATKFLLYTAISGILILVSFLglvwlsgassF 189

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  77 NYKQLGLWTFHQQTNFITLNLTLIALSMKLGLAPFHFWLPE-----------VTQGI--KLHT--------GLLLLTWQK 135
Cdd:PRK06473 190 DYEPLRSHTLPLSTQLLLLAPILVGFGIKIPLVPFHTWLPDahveastpvsvLLAGVllKLGTygllrfgvGLFPEAWVY 269

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 426405877 136 IAPlsilfqiynlldhtMILLMATLSIFMGAWGGLNQTQMRKIMAYSSIAHMGWML 191
Cdd:PRK06473 270 LAP--------------WLATWAVVSVLYGASCAIAQKDMKKMVAYSSIGHMGYIL 311
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 22-194 1.06e-07

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 53.23  E-value: 1.06e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  22 LSSNLLLMWVGLEFSLLAiTPLLI--DKKNPRSTEAATKYFVTQATASMMILLAIVLNYKQLGLWTF-------HQQTNF 92
Cdd:COG1009  129 LSDNLLLLFVFWELVGLC-SYLLIgfWYEKPSARRAARKAFLVTRVGDLGLLLGILLLGAIAGTLNFsellaaaPTILSS 207

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  93 ITLNLTLIALSM----KLGLAPFHFWLPE-----------------VTQGIKLhtglllltwqkIAPLSILFQIYNLLdH 151
Cdd:COG1009  208 PLLTLILLLLLLgafgKSAQFPLHFWLPDamegptpvsallhaatmVKAGVYL-----------LARLSPLFALSPVW-L 275

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 426405877 152 TMILLMATLSIFMGAWGGLNQTQMRKIMAYSSIAHMGWMLAIL 194
Cdd:COG1009  276 TVVAIIGAITALFAALIALAQTDIKRVLAYSTVSQLGYMFLAL 318
PRK12663 PRK12663
Na+/H+ antiporter subunit D;
22-293 8.42e-07

Na+/H+ antiporter subunit D;


Pssm-ID: 237163 [Multi-domain]  Cd Length: 497  Bit Score: 50.33  E-value: 8.42e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  22 LSSNLLLMWVGLEFSLLAITPLLIDKKNPRSTEAATKYFVTQATASMMILLAIVLNYKQLGLWTF-----------HQQT 90
Cdd:PRK12663 126 LTGDLFNLYVWFEVMLIASFVLITLGQEREQLRGAIKYVVLNLIGSWLFLLGIGLLYGTFGTLNMahiamrlndmgDTAT 205

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  91 NFITLNLTLIALSMKLGLAPFhFWLPEVTQGIKLHTGLL---LLTWQKIAPL----SILFQIYNLLDHTMILLMATLSIF 163
Cdd:PRK12663 206 LTTIALLFLLAFGMKAALFPF-MWLPAAYHTPNTEVAALfaaLLTKVGIYALirvfTLLFPQERELLHPLLATMAAITMV 284

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877 164 MGAWGGLNQTQMRKIMAYSSIAHMGWMLAILPYNpTMTLLNLTIYILLTIPMF---------ILLILNSSTTINSMSLLW 234
Cdd:PRK12663 285 IGALGALAYKDIRRIAGYQVISSIGFILLGLALG-TPAGINGAIFYLVHDMVVktalfliagSLVRLTGYRSLQYLGGLY 363

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 426405877 235 NKTPTILTIIPLILLSLGGLPPLTGFLPKWAIITELLKNN------CLILTTLMAMMALLNLFFY 293
Cdd:PRK12663 364 RKEPLFGALFLILIFAIGGLPPFSGFWGKVLLVQGALDNGayillaLMLITSLITMYSLFRIFFL 428
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 55-191 1.67e-06

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 49.43  E-value: 1.67e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  55 AATKYFVTQATASMMILLAI----VLNYKQLGLWTFHQQTNF-ITLNLT-------LIALSMKLGLAPFHFWLPEV---- 118
Cdd:PRK05846 162 AATKFFLYTLLGSLLMLVAIiylvVVYYNATGTFDIADLLNLpLPPGVQywlflafFIAFAVKMPMFPLHTWLPDAhvqa 241

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877 119 -TQGIKLHTGLLLltwqKIAP---LSILFQIYNLLDHTMILLMATLSIFM---GAWGGLNQTQMRKIMAYSSIAHMGWML 191
Cdd:PRK05846 242 pTAGSVLLAGILL----KMGAyglLRFSLPLFPDASHEFAPIIITLGVIAiiyGALVALAQTDIKKLIAYSSISHMGFVT 317
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 20-191 1.93e-06

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 49.16  E-value: 1.93e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  20 TMLSSNLLLMWVGLEFSLLAITPLLIDKKNPRSTEAATKYFVTQATASMMILLAIVLNY----KQLG------LWT---- 85
Cdd:PRK06458 124 ALTSNNLGLMWVAIEATTLSSALLVGIYRTRASLEAAWKYIIICSVGVAFALFGTILVYanaaTVMGdgemaiLWTellk 203

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  86 ----FHQQTNFITLNLTLIALSMKLGLAPFHFWLPE-----------VTQGIKLHTGLLLLTWQKIAplsILFQIYNLLD 150
Cdd:PRK06458 204 haslLDPTLMKLAFVFLLIGFGTKVGLFPMHAWLPDahseapspvsaLLSGVLLNVALYAVLRYYIL---IDAAIGSDFP 280

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 426405877 151 HTMILLMATLSIFMGAWGGLNQTQMRKIMAYSSIAHMGWML 191
Cdd:PRK06458 281 GRLLLIFGLLSVLVAAFFLLRQRDIKRLFAYSSIEHMGLIA 321
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
7-263 9.43e-06

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 47.35  E-value: 9.43e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877   7 IIIYSTIFLGPIITMLSSNLLLMWVGLEfsLLAITPLLID---KKNPRSTEAATKYFVTQATASMMILLAIVLNYkqlGL 83
Cdd:PRK02504 113 AAILLTATLGGMFLSGATELVMIFISLE--TLSIASYLLTgymKRDPRSNEAALKYLLIGAASSAIFLYGSSLLY---GL 187

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  84 WTFHQQTNFITLNLT-------LIAL-------SMKLGLAPFHFWLPEVTQGIKLHTGLLLLTWQKIA----PLSILFQI 145
Cdd:PRK02504 188 SGGSTQLSAIALALItspslglALALvfviagiAFKISAVPFHQWTPDVYEGSPTPVVAFLSVGSKAAgfalAIRLLVTA 267

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877 146 YNLLD---HTMILLMATLSIFMGAWGGLNQTQMRKIMAYSSIAHMGWMLAILPYNP----TMTLLNLTIYILLTIPMFIL 218
Cdd:PRK02504 268 FPSFDeqwKLLFTALAILSMVLGNVVALAQTSMKRMLAYSSIGQAGFVMIGLVAGTeagyASMVFYLLAYLFMNLGAFAC 347

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 426405877 219 LILNSSTT----INSMSLLWNKTPTILTIIPLILLSLGGLPPLTGFLPK 263
Cdd:PRK02504 348 VILFSLRTgtdqISDYAGLYQKDPLLTLGLSLCLLSLGGIPPLAGFFGK 396
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 18-191 3.24e-05

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 45.41  E-value: 3.24e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  18 IITMLSSNLLLMWVGLEFSLLAITPLLIDKKNPRSTEAATKYFVTQATASMMILLA----------IVLNYKQLGLWTFH 87
Cdd:PRK12561 101 IGVFLAQDLLLFFLMWELELVPVYLLISIWGGQKRLYAATKFILYTALASIFILVAglalalsgdtFTFDLAELGAKSYP 180

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  88 QQTNFITLNLTLIALSMKLGLAPFHFWLPE-----------VTQG----------IKLHTGLLLLTWQKIAPLSILFQIY 146
Cdd:PRK12561 181 LALELLLYAGFLIAFGVKLPIFPLHTWLPDahgeasapvsmILAGvllkmggyalIRFNVQMLPDAHVYFAPALAILGVV 260

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 426405877 147 NlldhtmillmatlsIFMGAWGGLNQTQMRKIMAYSSIAHMGWML 191
Cdd:PRK12561 261 N--------------IIYGALNAFAQDNVKRRLAYSSVSHMGFVL 291
PRK07363 PRK07363
NADH-quinone oxidoreductase subunit M;
21-191 8.21e-05

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 180945 [Multi-domain]  Cd Length: 501  Bit Score: 44.32  E-value: 8.21e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  21 MLSSNLLLMWVGLEFSLLAITPLLIDKKNPRSTEAATKYFVTQATASMMIL---LAIVL-------NYKQLGLWTFHQQT 90
Cdd:PRK07363 124 LLAQNLLLFFLFYELELIPFYLLIAIWGGEKRGYASIKFLIYTAVSGLLVLaafLGIVWlsgstsfDYDAISTQNLSLNT 203

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  91 NFITLNLTLIALSMKLGLAPFHFWLPEV--------------------TQG-IKLHTGLLLLTWQKIAPlsilfqiynll 149
Cdd:PRK07363 204 QLILLTGLLLGFGIKIPLVPLHTWLPDAyteaspavaillggvlaklgTYGlLRFGLQLFPQTWSLVAP----------- 272

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 426405877 150 dhtMILLMATLSIFMGAWGGLNQTQMRKIMAYSSIAHMGWML 191
Cdd:PRK07363 273 ---GLAIIGTISVIYGALSAIAQKDIKRMVAYSSIGHMGYIL 311
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 23-191 9.21e-05

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 43.98  E-value: 9.21e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  23 SSNLLLMWVGLEFSLLaITPLLIDKKNPRST-EAATKYFVTQATASMMILLAIVLNY----KQLG----LWT-------- 85
Cdd:PRK08676 121 SDNLALFWIFAELTTV-FSAMLIAILSARENiDAALKYIFIASTAMIFAFIGLIFLFsltrQALGtgtlNWTelaahasl 199

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  86 FHQQTNFITLNLTLIALSMKLGLAPFHFWLPEV-TQGIKLHTGLLLLTWQKIAPLSILfQIYNLLDHT--------MILL 156
Cdd:PRK08676 200 LSPSVLGASFLFIFIGFLAKSGLVPFHTWLPAAyAKAPSVVSALLSGTVLNIGIYGIL-RLSALLRQSgaaeqfsnVLIG 278

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 426405877 157 MATLSIFMGAWGGLNQTQMRKIMAYSSIAHMGWML 191
Cdd:PRK08676 279 LGIFSIAVAAFSMLSQRNLKKLIAFSSIEHMGLML 313
PRK08377 PRK08377
NADH dehydrogenase subunit N; Validated
 8-188 3.19e-04

NADH dehydrogenase subunit N; Validated


Pssm-ID: 181406 [Multi-domain]  Cd Length: 494  Bit Score: 42.45  E-value: 3.19e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877   8 IIYSTIFLGPIITMLSSNLLLMWVGLEFSLLAITPLLIDKKNPRSTEAATKYFVTQATASMMILLAIVLNYKQLGLWTFH 87
Cdd:PRK08377 112 MLFLLLMLGATGMIATGDIFNLFVFMEITAITAYALTAYNKTGEAAEASMKYIVLGGIGSSFFLIGVALIYGATGTLNMA 191

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  88 QQTNFIT----------LNLTLIALSMKLGLAPFHFWLPEVTQGIKLHTGLLLLTWQKIAPLSILFQIYNLLDHT----- 152
Cdd:PRK08377 192 HIAQLAGtidptvaqvgLALLIFGLAVEAELFPLNAWAPDAYQAAPHPITVMFSAFVVKAGLYAMARILYLMQNAngwss 271

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 426405877 153 ---MILLMATLSIFMGAWGGLNQTQMRKIMAYSSIAHMG 188
Cdd:PRK08377 272 vlkLVIIMATLTVFFAELSALRQKNVKRMIAYSSIGQVG 310
PRK12650 PRK12650
DUF4040 family protein;
12-192 7.73e-04

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 41.57  E-value: 7.73e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  12 TIFLGPIITM-LSSNLLLMWVGLEFSLLAiTPLLIDKKNPRSTEAATKYFVTQATASMMILLAIVLNYKQLG-------- 82
Cdd:PRK12650 117 TAFMAAMLLLvLADDVVVLFVAWELVSLA-SFFLIARSGSGGEAGSIRTLILTFFGGLTLLAAVAIAATQTGttslsgil 195

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  83 ---LWTfhQQTNFITLNLTLIALSM--KLGLAPFHFWLPEVTQGIK-----LHT------GLLLLTwqkiaPLSILF--- 143
Cdd:PRK12650 196 hsdVWA--EKPGLTTVVAVLIAVAAftKSAQFPFHFWLPEAMAAITpvsafLHAaavvkaGIYLLL-----RFSPVFhdv 268

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 426405877 144 QIYNLLDHTMILLMAtlsiFMGAWGGLNQTQMRKIMAYSSIAHMGWMLA 192
Cdd:PRK12650 269 AVWNWLLIIVGMITA----LMGAVFAVQKTDLKKLTAYSTVSQLGWIVA 313
PRK06589 PRK06589
putative monovalent cation/H+ antiporter subunit D; Reviewed
 2-191 8.36e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235835 [Multi-domain]  Cd Length: 489  Bit Score: 40.96  E-value: 8.36e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877   2 NPITLIIIYSTIFLGPIITmLSSNLLLMWVGLEFSLLAITPLLIDKKNPRSTEAATKYF-VTQATASMMILLAIVLNYKQ 80
Cdd:PRK06589 115 SSRFLFFFNLTILIGVLIA-LSSDLFTMFVCYELLTISTAFLIGHTRNNISLSGGYKYLkILMISALLLFLPAVILIYTK 193

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  81 LGLWTFHQQTNF-----ITLNLTLIALSMKLGLAPFHFWLPE-----------------VTQGIKLHTGLLLLTWqKIAP 138
Cdd:PRK06589 194 TGNLDFVSGGLFsknqsIILLLMFIYGIAKTAIFPVHSWLPAamvahypvsallhavivVKTGLFCIYKILLYIF-GLSY 272

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 426405877 139 LSILFQIYNLLdhtmiLLMATLSIFMGAWGGLNQTQMRKIMAYSSIAHMGWML 191
Cdd:PRK06589 273 LQRIFAEFNWL-----IFIPIVSIFYSSLKALKTDNIKKILAYSTISQLSLAL 320
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 10-188 2.48e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 39.57  E-value: 2.48e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  10 YSTIFLGPIITML----SSNLLLMWVGLEFSLLAITPLLI-DKKNPRSTEAATKYFVTQATASMMILLAIVLNY------ 78
Cdd:PRK12667 115 YYTLLLGLEAGMLgillTGDAFNLFVMLEVLSISAYGLVAyYRDRGDAVEAAIKYALIGAVGTTLYFLALAFLYatfgtl 194

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  79 -------KQLGLWtFHQQTN---------FITLNLTLIALSMKLGLAPFHFWLPEV-----------TQGIKLHTGLlll 131
Cdd:PRK12667 195 nmadlsaKIRGLS-FPLTGGlagnpplalGVALALALWAFTIKAAIFPNHFWLPDAhpaapspvsamLSGLVVNVGA--- 270

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 426405877 132 twqkIAPLSILFQIYNLLDHT---------MILLMATLSIFMGAWGGLNQTQMRKIMAYSSIAHMG 188
Cdd:PRK12667 271 ----YAIIRFLYTIFGISPSLidfraalspILIILGAVSAIIGALMMVVQKDVKRLLAYSTISHMG 332
PRK02546 PRK02546
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 16-191 3.34e-03

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 235050 [Multi-domain]  Cd Length: 525  Bit Score: 39.30  E-value: 3.34e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  16 GPIITMLSSNLLLMWVGLEFSLLAITPLLIDKKNPRSTEAATKYFVTQATASMMILLA----------IVLNYKQLGLWT 85
Cdd:PRK02546 127 GQIAVFAVQDMLLFFLAWELELIPVYLLLAIWGGKKRQYAATKFILYTAGSSLFILLAalamafygdtPTFDMTALAAKD 206

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426405877  86 FHQQTNFITLNLTLIALSMKLGLAPFHFWLP----EVTQ-------GIKLHTG----------LLLLTWQKIAPLSILFQ 144
Cdd:PRK02546 207 FGLGFQLLCYAGLLIAYGVKLPIVPLHTWLPdahgEATApvhmllaGILLKMGgyallrmnagMLPDAHAQFAPLLIVLG 286

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 426405877 145 IYNLLdhtmillMATLSIFMgawgglnQTQMRKIMAYSSIAHMGWML 191
Cdd:PRK02546 287 VVNII-------YAALTSFA-------QRNLKRKIAYSSISHMGFVL 319
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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