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Conserved domains on  [gi|40796150|ref|NP_955603|]
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p14 MA [Fujinami sarcoma virus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Retro_M super family cl03726
Retroviral M domain; Retroviruses contain a small protein, MA (matrix), which forms a protein ...
 1-86 3.19e-36

Retroviral M domain; Retroviruses contain a small protein, MA (matrix), which forms a protein lining immediately beneath the phospholipid membrane of the mature virus particle. MA is located in the N-terminal region of the Gag precursor polyprotein. The N-terminal segment of MA proteins directs the Gag protein to the plasma membrane where budding takes place, and has been called the M domain. This domain forms an alpha helical bundle structure.


The actual alignment was detected with superfamily member pfam02813:

Pssm-ID: 460707  Cd Length: 86  Bit Score: 120.26  E-value: 3.19e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40796150     1 MEAVIKVISSACKTYCGKTSPSKKEIGAMLSQLQKEGLLMSLSDLYSPGSWDPITAALTQRAMVLGKSGELKTWGLVLGA 80
Cdd:pfam02813   1 EAAIIKIISAACKTCCGKSPPKKEEGAALLLLLKEEGLLMPPDDLSPGGSDDIIAAALQQAAMLGGKGEEKKTGGLLGAA 80


                  ....*.
gi 40796150    81 LKAARE 86
Cdd:pfam02813  81 KAAAEE 86
 
Name Accession Description Interval E-value
Retro_M pfam02813
Retroviral M domain; Retroviruses contain a small protein, MA (matrix), which forms a protein ...
 1-86 3.19e-36

Retroviral M domain; Retroviruses contain a small protein, MA (matrix), which forms a protein lining immediately beneath the phospholipid membrane of the mature virus particle. MA is located in the N-terminal region of the Gag precursor polyprotein. The N-terminal segment of MA proteins directs the Gag protein to the plasma membrane where budding takes place, and has been called the M domain. This domain forms an alpha helical bundle structure.


Pssm-ID: 460707  Cd Length: 86  Bit Score: 120.26  E-value: 3.19e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40796150     1 MEAVIKVISSACKTYCGKTSPSKKEIGAMLSQLQKEGLLMSLSDLYSPGSWDPITAALTQRAMVLGKSGELKTWGLVLGA 80
Cdd:pfam02813   1 EAAIIKIISAACKTCCGKSPPKKEEGAALLLLLKEEGLLMPPDDLSPGGSDDIIAAALQQAAMLGGKGEEKKTGGLLGAA 80


                  ....*.
gi 40796150    81 LKAARE 86
Cdd:pfam02813  81 KAAAEE 86
 
Name Accession Description Interval E-value
Retro_M pfam02813
Retroviral M domain; Retroviruses contain a small protein, MA (matrix), which forms a protein ...
 1-86 3.19e-36

Retroviral M domain; Retroviruses contain a small protein, MA (matrix), which forms a protein lining immediately beneath the phospholipid membrane of the mature virus particle. MA is located in the N-terminal region of the Gag precursor polyprotein. The N-terminal segment of MA proteins directs the Gag protein to the plasma membrane where budding takes place, and has been called the M domain. This domain forms an alpha helical bundle structure.


Pssm-ID: 460707  Cd Length: 86  Bit Score: 120.26  E-value: 3.19e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40796150     1 MEAVIKVISSACKTYCGKTSPSKKEIGAMLSQLQKEGLLMSLSDLYSPGSWDPITAALTQRAMVLGKSGELKTWGLVLGA 80
Cdd:pfam02813   1 EAAIIKIISAACKTCCGKSPPKKEEGAALLLLLKEEGLLMPPDDLSPGGSDDIIAAALQQAAMLGGKGEEKKTGGLLGAA 80


                  ....*.
gi 40796150    81 LKAARE 86
Cdd:pfam02813  81 KAAAEE 86
Retro_M pfam02813
Retroviral M domain; Retroviruses contain a small protein, MA (matrix), which forms a protein ...
 2-87 4.01e-36

Retroviral M domain; Retroviruses contain a small protein, MA (matrix), which forms a protein lining immediately beneath the phospholipid membrane of the mature virus particle. MA is located in the N-terminal region of the Gag precursor polyprotein. The N-terminal segment of MA proteins directs the Gag protein to the plasma membrane where budding takes place, and has been called the M domain. This domain forms an alpha helical bundle structure.


Pssm-ID: 460707  Cd Length: 86  Bit Score: 119.87  E-value: 4.01e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40796150     2 EAVIKVISSACKTYCGKTSPSKKEIGAMLSQLQKEGLLMSLSDLYSPGSWDPITAALTQRAMVLGKSGELKTWGLVLGAL 81
Cdd:pfam02813   1 EAAIIKIISAACKTCCGKSPPKKEEGAALLLLLKEEGLLMPPDDLSPGGSDDIIAAALQQAAMLGGKGEEKKTGGLLGAA 80


                  ....*.
gi 40796150    82 KAAREE 87
Cdd:pfam02813  81 KAAAEE 86
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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