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Conserved domains on  [gi|400286385|ref|NP_001257859|]
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interferon-induced protein with tetratricopeptide repeats 1 isoform 3 [Homo sapiens]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 18414217)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes; similar to Homo sapiens Interferon-induced protein with tetratricopeptide repeats 1

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  30708253|10517866
SCOP:  3001345

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 125-434 2.04e-17

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 82.08  E-value: 2.04e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 125 NYERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNHKpfsllplrQAVRLNPDNGYIKVLLALKLQDEGQEAE 204
Cdd:COG2956   23 QPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQ--------KLLERDPDRAEALLELAQDYLKAGLLDR 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 205 GEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQmiqikeatkgqprgqnr 284
Cdd:COG2956   95 AEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQ----------------- 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 285 EKLDKmirsAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLcmkpvveetmqdihfhygrfqefqkKSD 364
Cdd:COG2956  158 GDYDE----AIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERAL-------------------------EQD 208

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 365 VNAIIHYLKAIKIEQASLTRDKSINSLKKLvlrkLRRKALDLESLSLLGFVYKLEGNmNEALEYYERALR 434
Cdd:COG2956  209 PDYLPALPRLAELYEKLGDPEEALELLRKA----LELDPSDDLLLALADLLERKEGL-EAALALLERQLR 273
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
24-214 9.48e-11

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 61.95  E-value: 9.48e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385  24 HNLLAYVKHLKGQNEEALKSLKEAENLMQEEHDnqanvrslvTWGNFAWMYYHMGRLAEAQTYLDKVENICKKLSNPFRY 103
Cdd:COG0457   11 YNNLGLAYRRLGRYEEAIEDYEKALELDPDDAE---------ALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNN 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 104 RmecpeidceeGWALLKCGgkNYERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNhkpfsllpLRQAVRLNP 183
Cdd:COG0457   82 L----------GLALQALG--RYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEA--------YERALELDP 141

                        170       180       190
                 ....*....|....*....|....*....|.
gi 400286385 184 DNGYIKVLLALKLQDEGQEAEGEKYIEEALA 214
Cdd:COG0457  142 DDADALYNLGIALEKLGRYEEALELLEKLEA 172
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 125-434 2.04e-17

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 82.08  E-value: 2.04e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 125 NYERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNHKpfsllplrQAVRLNPDNGYIKVLLALKLQDEGQEAE 204
Cdd:COG2956   23 QPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQ--------KLLERDPDRAEALLELAQDYLKAGLLDR 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 205 GEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQmiqikeatkgqprgqnr 284
Cdd:COG2956   95 AEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQ----------------- 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 285 EKLDKmirsAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLcmkpvveetmqdihfhygrfqefqkKSD 364
Cdd:COG2956  158 GDYDE----AIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERAL-------------------------EQD 208

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 365 VNAIIHYLKAIKIEQASLTRDKSINSLKKLvlrkLRRKALDLESLSLLGFVYKLEGNmNEALEYYERALR 434
Cdd:COG2956  209 PDYLPALPRLAELYEKLGDPEEALELLRKA----LELDPSDDLLLALADLLERKEGL-EAALALLERQLR 273
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 24-435 1.73e-14

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 75.89  E-value: 1.73e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385   24 HNLLAYVKHLKGQNEEALKSLKEAENLmqeeHDNQANVRSlvtwgNFAWMYYHMGRLAEAQTYLDKVENICKKLSNPFRY 103
Cdd:TIGR02917 196 LLLKGDLLLSLGNIELALAAYRKAIAL----RPNNIAVLL-----ALATILIEAGEFEEAEKHADALLKKAPNSPLAHYL 266

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385  104 RmecpeidceegwALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNhkpfsllpLRQAVRLNP 183
Cdd:TIGR02917 267 K------------ALVDFQKKNYEDARETLQDALKSAPEYLPALLLAGASEYQLGNLEQAYQY--------LNQILKYAP 326

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385  184 DNGYIKVLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLC 263
Cdd:TIGR02917 327 NSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAARTQLGIS 406

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385  264 YKAQmiqikeatkGQPRGqnrekldkmirsAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKA---EENFQKLLCMKP 340
Cdd:TIGR02917 407 KLSQ---------GDPSE------------AIADLETAAQLDPELGRADLLLILSYLRSGQFDKAlaaAKKLEKKQPDNA 465

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385  341 VVEETMQDIHfhygrfqeFQKKSDVNAIIHYLKAIKIEQASLT----------RDKSINSLKKLVLRKLRRKALDLESLS 410
Cdd:TIGR02917 466 SLHNLLGAIY--------LGKGDLAKAREAFEKALSIEPDFFPaaanlaridiQEGNPDDAIQRFEKVLTIDPKNLRAIL 537

                         410       420
                  ....*....|....*....|....*
gi 400286385  411 LLGFVYKLEGNMNEALEYYERALRL 435
Cdd:TIGR02917 538 ALAGLYLRTGNEEEAVAWLEKAAEL 562
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
24-214 9.48e-11

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 61.95  E-value: 9.48e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385  24 HNLLAYVKHLKGQNEEALKSLKEAENLMQEEHDnqanvrslvTWGNFAWMYYHMGRLAEAQTYLDKVENICKKLSNPFRY 103
Cdd:COG0457   11 YNNLGLAYRRLGRYEEAIEDYEKALELDPDDAE---------ALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNN 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 104 RmecpeidceeGWALLKCGgkNYERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNhkpfsllpLRQAVRLNP 183
Cdd:COG0457   82 L----------GLALQALG--RYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEA--------YERALELDP 141

                        170       180       190
                 ....*....|....*....|....*....|.
gi 400286385 184 DNGYIKVLLALKLQDEGQEAEGEKYIEEALA 214
Cdd:COG0457  142 DDADALYNLGIALEKLGRYEEALELLEKLEA 172
TPR_12 pfam13424
Tetratricopeptide repeat;
23-96 9.36e-06

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 43.53  E-value: 9.36e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 400286385   23 IHNLLAYVKHLKGQNEEALKSLKEAENLMQEEHDNQaNVRSLVTWGNFAWMYYHMGRLAEAQTYLDKVENICKK 96
Cdd:pfam13424   5 ALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPD-HPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
TPR_1 pfam00515
Tetratricopeptide repeat;
407-439 1.46e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 35.86  E-value: 1.46e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 400286385  407 ESLSLLGFVYKLEGNMNEALEYYERALRLAADF 439
Cdd:pfam00515   2 KALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 407-439 2.00e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 35.50  E-value: 2.00e-03
                           10        20        30
                   ....*....|....*....|....*....|...
gi 400286385   407 ESLSLLGFVYKLEGNMNEALEYYERALRLAADF 439
Cdd:smart00028   2 EALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 125-434 2.04e-17

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 82.08  E-value: 2.04e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 125 NYERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNHKpfsllplrQAVRLNPDNGYIKVLLALKLQDEGQEAE 204
Cdd:COG2956   23 QPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQ--------KLLERDPDRAEALLELAQDYLKAGLLDR 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 205 GEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQmiqikeatkgqprgqnr 284
Cdd:COG2956   95 AEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQ----------------- 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 285 EKLDKmirsAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLcmkpvveetmqdihfhygrfqefqkKSD 364
Cdd:COG2956  158 GDYDE----AIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERAL-------------------------EQD 208

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 365 VNAIIHYLKAIKIEQASLTRDKSINSLKKLvlrkLRRKALDLESLSLLGFVYKLEGNmNEALEYYERALR 434
Cdd:COG2956  209 PDYLPALPRLAELYEKLGDPEEALELLRKA----LELDPSDDLLLALADLLERKEGL-EAALALLERQLR 273
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 191-438 2.74e-17

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 81.70  E-value: 2.74e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 191 LLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQmiq 270
Cdd:COG2956   13 FKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKA--- 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 271 ikeatkgqprgqnrEKLDKmirsAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKPvveetmQDIH 350
Cdd:COG2956   90 --------------GLLDR----AEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGP------ENAH 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 351 FHYGRFQEFQKKSDV-NAIIHYLKAIKIEQAS----------LTRDKSINSLKKLVLRKLRRKALDLESLSLLGFVYKLE 419
Cdd:COG2956  146 AYCELAELYLEQGDYdEAIEALEKALKLDPDCarallllaelYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKL 225

                        250
                 ....*....|....*....
gi 400286385 420 GNMNEALEYYERALRLAAD 438
Cdd:COG2956  226 GDPEEALELLRKALELDPS 244
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 24-435 1.73e-14

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 75.89  E-value: 1.73e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385   24 HNLLAYVKHLKGQNEEALKSLKEAENLmqeeHDNQANVRSlvtwgNFAWMYYHMGRLAEAQTYLDKVENICKKLSNPFRY 103
Cdd:TIGR02917 196 LLLKGDLLLSLGNIELALAAYRKAIAL----RPNNIAVLL-----ALATILIEAGEFEEAEKHADALLKKAPNSPLAHYL 266

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385  104 RmecpeidceegwALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNhkpfsllpLRQAVRLNP 183
Cdd:TIGR02917 267 K------------ALVDFQKKNYEDARETLQDALKSAPEYLPALLLAGASEYQLGNLEQAYQY--------LNQILKYAP 326

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385  184 DNGYIKVLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLC 263
Cdd:TIGR02917 327 NSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAARTQLGIS 406

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385  264 YKAQmiqikeatkGQPRGqnrekldkmirsAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKA---EENFQKLLCMKP 340
Cdd:TIGR02917 407 KLSQ---------GDPSE------------AIADLETAAQLDPELGRADLLLILSYLRSGQFDKAlaaAKKLEKKQPDNA 465

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385  341 VVEETMQDIHfhygrfqeFQKKSDVNAIIHYLKAIKIEQASLT----------RDKSINSLKKLVLRKLRRKALDLESLS 410
Cdd:TIGR02917 466 SLHNLLGAIY--------LGKGDLAKAREAFEKALSIEPDFFPaaanlaridiQEGNPDDAIQRFEKVLTIDPKNLRAIL 537

                         410       420
                  ....*....|....*....|....*
gi 400286385  411 LLGFVYKLEGNMNEALEYYERALRL 435
Cdd:TIGR02917 538 ALAGLYLRTGNEEEAVAWLEKAAEL 562
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
179-438 3.64e-13

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 68.88  E-value: 3.64e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 179 VRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHH 258
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 259 QIGLCYKAQmiqikeatkgqprGQNREkldkmirsAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCM 338
Cdd:COG0457   81 NLGLALQAL-------------GRYEE--------ALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALEL 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 339 KPvveeTMQDIHFHYGRFQEFQKKSDvNAIIHYLKAIKIEQASLTRDKSINSLKKLVLRKLRRKALDLESLSLLGFVYKL 418
Cdd:COG0457  140 DP----DDADALYNLGIALEKLGRYE-EALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAIL 214

                        250       260
                 ....*....|....*....|
gi 400286385 419 EGNMNEALEYYERALRLAAD 438
Cdd:COG0457  215 TLAALAELLLLALALLLALR 234
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 20-256 4.86e-13

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 68.99  E-value: 4.86e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385  20 SVGIHNLLAYVKHLKGQNEEALKSLkeaENLMQEEHDNQANVRSLvtwgnfAWMYYHMGRLAEAQTYLDKVENICKKLSN 99
Cdd:COG2956   41 TVEAHLALGNLYRRRGEYDRAIRIH---QKLLERDPDRAEALLEL------AQDYLKAGLLDRAEELLEKLLELDPDDAE 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 100 PFRYRMECPEIDceegwallkcggKNYERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNhkpfsllpLRQAV 179
Cdd:COG2956  112 ALRLLAEIYEQE------------GDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEA--------LEKAL 171

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 400286385 180 RLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLL 256
Cdd:COG2956  172 KLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLL 248
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
115-267 1.49e-12

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 67.34  E-value: 1.49e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 115 GWALLKCGgkNYERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNhkpfsllpLRQAVRLNPDNGYIKVLLAL 194
Cdd:COG0457   15 GLAYRRLG--RYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALAD--------YEQALELDPDDAEALNNLGL 84

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 400286385 195 KLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQ 267
Cdd:COG0457   85 ALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKL 157
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 115-446 1.64e-12

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 69.73  E-value: 1.64e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385  115 GWALLKCGgkNYERAKACFEKVLEVDPENpessagyAISAYRLDGFKLATKNHKPfSLLPLRQAVRLN------------ 182
Cdd:TIGR02917 370 GEAYLALG--DFEKAAEYLAKATELDPEN-------AAARTQLGISKLSQGDPSE-AIADLETAAQLDpelgradlllil 439

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385  183 ----------------------PDNGYIKVLLALKLQDEGQEAEGEKYIEEAL----ANMSSQTYVFRYAAKfyrrKGSV 236
Cdd:TIGR02917 440 sylrsgqfdkalaaakklekkqPDNASLHNLLGAIYLGKGDLAKAREAFEKALsiepDFFPAAANLARIDIQ----EGNP 515

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385  237 DKALELLKKALQETPTSVLLHHQIGLCYKAQ------MIQIKEATKGQPRGQNREKL-------DKMIRSAIFHFESAVE 303
Cdd:TIGR02917 516 DDAIQRFEKVLTIDPKNLRAILALAGLYLRTgneeeaVAWLEKAAELNPQEIEPALAlaqyylgKGQLKKALAILNEAAD 595

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385  304 KKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKPVVEEtmqdIHFHYGRFQEFQKKSDvNAIIHYLKAIKIE----- 378
Cdd:TIGR02917 596 AAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSAL----ALLLLADAYAVMKNYA-KAITSLKRALELKpdnte 670

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 400286385  379 ----QASL-TRDKSINSLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERALRLAADFENSVRQG 446
Cdd:TIGR02917 671 aqigLAQLlLAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSSQNAIKLH 743
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 124-340 2.28e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 67.06  E-value: 2.28e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 124 KNYERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNhkpfsllpLRQAVRLNPDNGYIKVLLALKLQDEGQEA 203
Cdd:COG2956   56 GEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEEL--------LEKLLELDPDDAEALRLLAEIYEQEGDWE 127

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 204 EGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQmiqikeatkgqprgqn 283
Cdd:COG2956  128 KAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQ---------------- 191

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 400286385 284 rekldKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKP 340
Cdd:COG2956  192 -----GDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDP 243
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 38-322 1.45e-11

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 66.56  E-value: 1.45e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385  38 EEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLA-----EAQTYLDKVENICKKLSNPF--RYRMECPEI 110
Cdd:COG3914    1 AAAAALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLAllllaALAEAAAAALLALAAGEAAAaaAALLLLAAL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 111 DCEEGWALLKCGgkNYERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLAtknhkpfsLLPLRQAVRLNPDNGYIKV 190
Cdd:COG3914   81 LELAALLLQALG--RYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEA--------LAALRRALALNPDFAEAYL 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 191 LLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIgLCYKAQMIQ 270
Cdd:COG3914  151 NLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNL-LFALRQACD 229

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|..
gi 400286385 271 IKEATKGQPRGQNREKLDKMIRSAIFHFESAVEkkptfEVAHLDLARMYIEA 322
Cdd:COG3914  230 WEVYDRFEELLAALARGPSELSPFALLYLPDDD-----PAELLALARAWAQL 276
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
66-249 2.95e-11

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 63.49  E-value: 2.95e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385  66 TWGNFAWMYYHMGRLAEAQTYLDKVENICKKLSNPFRYRmecpeidceeGWALLKCGgkNYERAKACFEKVLEVDPENPE 145
Cdd:COG0457   10 AYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNL----------GLAYLRLG--RYEEALADYEQALELDPDDAE 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 146 SSAGYAISAYRLDGFKLATKNhkpfsllpLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRY 225
Cdd:COG0457   78 ALNNLGLALQALGRYEEALED--------YDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYN 149

                        170       180
                 ....*....|....*....|....
gi 400286385 226 AAKFYRRKGSVDKALELLKKALQE 249
Cdd:COG0457  150 LGIALEKLGRYEEALELLEKLEAA 173
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 33-336 4.67e-11

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 63.21  E-value: 4.67e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385  33 LKGQNEEALKSLKEAENLmqeehdNQANVRSLVTWGNfawMYYHMGRLAEAQTYLDKVEnickklsnpfryrmecpEIDC 112
Cdd:COG2956   20 LNGQPDKAIDLLEEALEL------DPETVEAHLALGN---LYRRRGEYDRAIRIHQKLL-----------------ERDP 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 113 EEGWALLKCGG-----KNYERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNhkpfsllpLRQAVRLNPDNGY 187
Cdd:COG2956   74 DRAEALLELAQdylkaGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEV--------LERLLKLGPENAH 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 188 IKVLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQ 267
Cdd:COG2956  146 AYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKL 225

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 400286385 268 miqikeatkgqprGQNREkldkmirsAIFHFESAVEKKPTfEVAHLDLARMYIEAGNHRKAEENFQKLL 336
Cdd:COG2956  226 -------------GDPEE--------ALELLRKALELDPS-DDLLLALADLLERKEGLEAALALLERQL 272
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 225-439 7.40e-11

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 62.44  E-value: 7.40e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 225 YAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYkaqmiqikeatkgqprgQNREKLDKmirsAIFHFESAVEK 304
Cdd:COG2956   13 FKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLY-----------------RRRGEYDR----AIRIHQKLLER 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 305 KPTFEVAHLDLARMYIEAGNHRKAEENFQKLLcmkpvvEETMQDIHFHYGRFQEFQKKSDvnaiihYLKAIKieqasltr 384
Cdd:COG2956   72 DPDRAEALLELAQDYLKAGLLDRAEELLEKLL------ELDPDDAEALRLLAEIYEQEGD------WEKAIE-------- 131

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 400286385 385 dksinslkklVLRKLRRKALDLESLSL-LGFVYKLEGNMNEALEYYERALRLAADF 439
Cdd:COG2956  132 ----------VLERLLKLGPENAHAYCeLAELYLEQGDYDEAIEALEKALKLDPDC 177
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
24-214 9.48e-11

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 61.95  E-value: 9.48e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385  24 HNLLAYVKHLKGQNEEALKSLKEAENLMQEEHDnqanvrslvTWGNFAWMYYHMGRLAEAQTYLDKVENICKKLSNPFRY 103
Cdd:COG0457   11 YNNLGLAYRRLGRYEEAIEDYEKALELDPDDAE---------ALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNN 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 104 RmecpeidceeGWALLKCGgkNYERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNhkpfsllpLRQAVRLNP 183
Cdd:COG0457   82 L----------GLALQALG--RYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEA--------YERALELDP 141

                        170       180       190
                 ....*....|....*....|....*....|.
gi 400286385 184 DNGYIKVLLALKLQDEGQEAEGEKYIEEALA 214
Cdd:COG0457  142 DDADALYNLGIALEKLGRYEEALELLEKLEA 172
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 192-340 1.52e-10

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 59.05  E-value: 1.52e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 192 LALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQmiqi 271
Cdd:COG4783   10 LAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKA---- 85

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 400286385 272 keatkgqprgqnrekldKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKP 340
Cdd:COG4783   86 -----------------GDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDP 137
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 238-440 2.14e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 62.70  E-value: 2.14e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 238 KALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEATKGQPRGQNREKLDKmIRSAIFHFESAVEKKPTFEVAHLDLAR 317
Cdd:COG3914   42 GLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGR-YEEALALYRRALALNPDNAEALFNLGN 120

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 318 MYIEAGNHRKAEENFQKLLCMKPvveeTMQDIHFHYGRFQEFQKKSDvNAIIHYLKAikieqasltrdksinslkklvlr 397
Cdd:COG3914  121 LLLALGRLEEALAALRRALALNP----DFAEAYLNLGEALRRLGRLE-EAIAALRRA----------------------- 172

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 400286385 398 kLRRKALDLESLSLLGFVYKLEGNMNEALEYYERALRLAADFE 440
Cdd:COG3914  173 -LELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNA 214
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 116-340 2.22e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 62.70  E-value: 2.22e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 116 WALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNHKPFSLLPLRQAVRLN-PDNGYIKVLLAL 194
Cdd:COG3914    7 LALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAAlLLLAALLELAAL 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 195 KLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMiQIKEA 274
Cdd:COG3914   87 LLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLG-RLEEA 165

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 400286385 275 TKgqprgqnrekldkmirsaifHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKP 340
Cdd:COG3914  166 IA--------------------ALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDP 211
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 36-439 4.68e-10

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 62.02  E-value: 4.68e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385   36 QNEEALKSLKEAENLmQEEHDNQANVRSLVtwgnfAWMYYHMGRLAEAQTYLDKVENIckklsNP--FRYRMECPEIDCE 113
Cdd:TIGR02917 443 RSGQFDKALAAAKKL-EKKQPDNASLHNLL-----GAIYLGKGDLAKAREAFEKALSI-----EPdfFPAAANLARIDIQ 511

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385  114 EGwallkcggkNYERAKACFEKVLEVDPENPESSAGYAisayrldGFKLATkNHKPFSLLPLRQAVRLNPDNGYIKVLLA 193
Cdd:TIGR02917 512 EG---------NPDDAIQRFEKVLTIDPKNLRAILALA-------GLYLRT-GNEEEAVAWLEKAAELNPQEIEPALALA 574

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385  194 LKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHhqiglcykaqmiqiKE 273
Cdd:TIGR02917 575 QYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALAL--------------LL 640

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385  274 ATKGQPRGQNREKldkmirsAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKP---VVEETMQDIH 350
Cdd:TIGR02917 641 LADAYAVMKNYAK-------AITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPkaaLGFELEGDLY 713

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385  351 FHYGRFQEfqkksdvnAIIHYLKAIKIEQASLT---------RDKSINSLKKLVLRKLRRKALDLESLSLLGFVYKLEGN 421
Cdd:TIGR02917 714 LRQKDYPA--------AIQAYRKALKRAPSSQNaiklhrallASGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKD 785

                         410
                  ....*....|....*...
gi 400286385  422 MNEALEYYERALRLAADF 439
Cdd:TIGR02917 786 YDKAIKHYQTVVKKAPDN 803
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 128-253 1.30e-09

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 56.17  E-value: 1.30e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 128 RAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNhkpfsllpLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEK 207
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAA--------YEKALRLDPDNADALLDLAEALLAAGDTEEAEE 72

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 400286385 208 YIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTS 253
Cdd:COG4235   73 LLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPAD 118
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
230-445 2.70e-09

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 57.71  E-value: 2.70e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 230 YRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQmiqikeatkgqprGQNREkldkmirsAIFHFESAVEKKPTFE 309
Cdd:COG0457   18 YRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRL-------------GRYEE--------ALADYEQALELDPDDA 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 310 VAHLDLARMYIEAGNHRKAEENFQKLLCMKPVVEEtmqdIHFHYGRFQEFQKKSDvNAIIHYLKAIKIEQAsltrdksin 389
Cdd:COG0457   77 EALNNLGLALQALGRYEEALEDYDKALELDPDDAE----ALYNLGLALLELGRYD-EAIEAYERALELDPD--------- 142

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 400286385 390 slkklvlrklrrkalDLESLSLLGFVYKLEGNMNEALEYYERALRLAADFENSVRQ 445
Cdd:COG0457  143 ---------------DADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAAL 183
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 115-214 4.65e-09

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 54.63  E-value: 4.65e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 115 GWALLKCGgkNYERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNhkpfsllpLRQAVRLNPDNGYIKVLLAL 194
Cdd:COG4235   24 GRAYLRLG--RYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEEL--------LERALALDPDNPEALYLLGL 93

                         90       100
                 ....*....|....*....|
gi 400286385 195 KLQDEGQEAEGEKYIEEALA 214
Cdd:COG4235   94 AAFQQGDYAEAIAAWQKLLA 113
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 175-267 5.19e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 54.43  E-value: 5.19e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 175 LRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSV 254
Cdd:COG4783   27 LEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHP 106

                         90
                 ....*....|...
gi 400286385 255 LLHHQIGLCYKAQ 267
Cdd:COG4783  107 EAYLRLARAYRAL 119
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
124-215 4.21e-08

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 50.55  E-value: 4.21e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 124 KNYERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLAtknhkpfslLPLRQAVRLNPDNGYIKVLLALKLQDEGQEA 203
Cdd:COG3063    6 GDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEA---------IALEKALKLDPNNAEALLNLAELLLELGDYD 76

                         90
                 ....*....|..
gi 400286385 204 EGEKYIEEALAN 215
Cdd:COG3063   77 EALAYLERALEL 88
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 294-436 5.74e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 51.16  E-value: 5.74e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 294 AIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKPvveeTMQDIHFHYGRFQEFQKKSDvnaiihylK 373
Cdd:COG4235    2 AIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDP----DNADALLDLAEALLAAGDTE--------E 69

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 400286385 374 AIKIEQASLTRDKSinslkklvlrklrrkalDLESLSLLGFVYKLEGNMNEALEYYERALRLA 436
Cdd:COG4235   70 AEELLERALALDPD-----------------NPEALYLLGLAAFQQGDYAEAIAAWQKLLALL 115
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 115-439 1.19e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 54.32  E-value: 1.19e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385  115 GWALLKCGGKNYERAKACFEKVLEVDPENpessagyaISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLAL 194
Cdd:TIGR02917 164 GLAQLALAENRFDEARALIDEVLTADPGN--------VDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALAT 235

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385  195 KLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETP---TSVLL----HHQIGLCYKAQ 267
Cdd:TIGR02917 236 ILIEAGEFEEAEKHADALLKKAPNSPLAHYLKALVDFQKKNYEDARETLQDALKSAPeylPALLLagasEYQLGNLEQAY 315

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385  268 ---------------------MIQIKE--ATKGQPRGQNREKLD-----------------KMIRSAIFHFESAVEKKPT 307
Cdd:TIGR02917 316 qylnqilkyapnshqarrllaSIQLRLgrVDEAIATLSPALGLDpddpaalsllgeaylalGDFEKAAEYLAKATELDPE 395

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385  308 FEVAHLDLARMYIEAGNHRKAEENFQKLLCMKPVVeetmqdihfhygrfqefqKKSDVNAIIHYLKAIKIeqasltrDKS 387
Cdd:TIGR02917 396 NAAARTQLGISKLSQGDPSEAIADLETAAQLDPEL------------------GRADLLLILSYLRSGQF-------DKA 450

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|..
gi 400286385  388 INSLKKLvLRKLRRKALdleSLSLLGFVYKLEGNMNEALEYYERALRLAADF 439
Cdd:TIGR02917 451 LAAAKKL-EKKQPDNAS---LHNLLGAIYLGKGDLAKAREAFEKALSIEPDF 498
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 20-377 1.23e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 54.32  E-value: 1.23e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385   20 SVGIHNLLAYVKHLKGQNEEALKSLKEAenlMQEEHDNQANVRSLVTWgnfawmYYHMGRLAEAQTYLDKVENICKKlsn 99
Cdd:TIGR02917 532 NLRAILALAGLYLRTGNEEEAVAWLEKA---AELNPQEIEPALALAQY------YLGKGQLKKALAILNEAADAAPD--- 599

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385  100 pfryrmeCPEIDCEEGWALLKcgGKNYERAKACFEKVLEVDPENPEssagyaisAYRLDGFKLATKNHKPFSLLPLRQAV 179
Cdd:TIGR02917 600 -------SPEAWLMLGRAQLA--AGDLNKAVSSFKKLLALQPDSAL--------ALLLLADAYAVMKNYAKAITSLKRAL 662

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385  180 RLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTS---VLL 256
Cdd:TIGR02917 663 ELKPDNTEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSSqnaIKL 742

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385  257 HHQIGLCYKAQmiqikEATKGQPRGQNREKLDKMIRS--------------AIFHFESAVEKKPTFEVAHLDLARMYIEA 322
Cdd:TIGR02917 743 HRALLASGNTA-----EAVKTLEAWLKTHPNDAVLRTalaelylaqkdydkAIKHYQTVVKKAPDNAVVLNNLAWLYLEL 817

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 400286385  323 GNHRkAEENFQKLLCMKP---VVEETMQDIHFHYGRFQEfqkksdvnAIIHYLKAIKI 377
Cdd:TIGR02917 818 KDPR-ALEYAERALKLAPnipAILDTLGWLLVEKGEADR--------ALPLLRKAVNI 866
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 27-185 2.45e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 49.81  E-value: 2.45e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385  27 LAYVKHLKGQNEEALKSLKEAenLMQEEHDNQAnvrslvtWGNFAWMYYHMGRLAEAQTYLDKVENIckklsNPfryrmE 106
Cdd:COG4783   10 LAQALLLAGDYDEAEALLEKA--LELDPDNPEA-------FALLGEILLQLGDLDEAIVLLHEALEL-----DP-----D 70

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 400286385 107 CPEIDCEEGWALLKCGgkNYERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNhkpfsllpLRQAVRLNPDN 185
Cdd:COG4783   71 EPEARLNLGLALLKAG--DYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAA--------LEKALELDPDD 139
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 19-249 9.03e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 50.11  E-value: 9.03e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385  19 YSVGIHNLLAYVKHLKGQNEEALKSLKEAENLMQEEhdnqanvrslvtwgnfAWMYYHMGRLAEAQtyldkvenickkls 98
Cdd:COG2956  108 DDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPEN----------------AHAYCELAELYLEQ-------------- 157

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385  99 npfryrmecpeidceegwallkcggKNYERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNhkpfsllpLRQA 178
Cdd:COG2956  158 -------------------------GDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAA--------LERA 204

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 400286385 179 VRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYaAKFYRRKGSVDKALELLKKALQE 249
Cdd:COG2956  205 LEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLAL-ADLLERKEGLEAALALLERQLRR 274
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 217-378 1.37e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 47.49  E-value: 1.37e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 217 SSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYkaqmiqikeatkgqprgQNREKLDKmirsAIF 296
Cdd:COG4783    1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEIL-----------------LQLGDLDE----AIV 59

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 297 HFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKPvveeTMQDIHFHYGRFQEFQKKSDvNAIIHYLKAIK 376
Cdd:COG4783   60 LLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDP----EHPEAYLRLARAYRALGRPD-EAIAALEKALE 134


                 ..
gi 400286385 377 IE 378
Cdd:COG4783  135 LD 136
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 124-215 1.49e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 48.03  E-value: 1.49e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 124 KNYERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNhkpfsllpLRQAVRLNPDNGYIKVLLALKLQDEGQEA 203
Cdd:COG5010   68 GDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEY--------YEKALALSPDNPNAYSNLAALLLSLGQDD 139

                         90
                 ....*....|..
gi 400286385 204 EGEKYIEEALAN 215
Cdd:COG5010  140 EAKAALQRALGT 151
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 172-341 1.67e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 47.65  E-value: 1.67e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 172 LLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETP 251
Cdd:COG5010    6 GFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDP 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 252 TSVLLHHQIGLCYKAQmiqikeatkgqprGQNREkldkmirsAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEEN 331
Cdd:COG5010   86 NNPELYYNLALLYSRS-------------GDKDE--------AKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAA 144

                        170
                 ....*....|
gi 400286385 332 FQKLLCMKPV 341
Cdd:COG5010  145 LQRALGTSPL 154
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
230-340 1.70e-06

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 45.93  E-value: 1.70e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 230 YRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQmiqikeatkgqprgqnrEKLDKMIRsaifhFESAVEKKPTFE 309
Cdd:COG3063    2 YLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQ-----------------GRYDEAIA-----LEKALKLDPNNA 59

                         90       100       110
                 ....*....|....*....|....*....|.
gi 400286385 310 VAHLDLARMYIEAGNHRKAEENFQKLLCMKP 340
Cdd:COG3063   60 EALLNLAELLLELGDYDEALAYLERALELDP 90
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 19-336 6.64e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 48.54  E-value: 6.64e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385   19 YSVGIHNLLAYVKHLKGQNEEALKSLKEAenLMQEEHDNQANVRslvtwgnfawmyyhMGRLAEAQTYLDKVENICKKLS 98
Cdd:TIGR02917 633 DSALALLLLADAYAVMKNYAKAITSLKRA--LELKPDNTEAQIG--------------LAQLLLAAKRTESAKKIAKSLQ 696

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385   99 NPfryRMECPEIDCEEGWALLKcgGKNYERAKACFEKVLEVDPenpesSAGYAIsayRLDGFKLATKNhKPFSLLPLRQA 178
Cdd:TIGR02917 697 KQ---HPKAALGFELEGDLYLR--QKDYPAAIQAYRKALKRAP-----SSQNAI---KLHRALLASGN-TAEAVKTLEAW 762

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385  179 VRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRrKGSVDKALELLKKALQETPTSvllhH 258
Cdd:TIGR02917 763 LKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAWLYL-ELKDPRALEYAERALKLAPNI----P 837

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 400286385  259 QIGLCYKAQMIQIKEAtkgqprgqnrekldkmiRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLL 336
Cdd:TIGR02917 838 AILDTLGWLLVEKGEA-----------------DRALPLLRKAVNIAPEAAAIRYHLALALLATGRKAEARKELDKLL 898
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 175-267 7.35e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 45.38  E-value: 7.35e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 175 LRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSV 254
Cdd:COG4235    6 LRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNP 85

                         90
                 ....*....|...
gi 400286385 255 LLHHQIGLCYKAQ 267
Cdd:COG4235   86 EALYLLGLAAFQQ 98
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
302-439 8.12e-06

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 46.92  E-value: 8.12e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 302 VEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKPVVEETMQ---DIHFHYGRFQEfqkksdvnAIIHYLKAIKIE 378
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYnlgLAYLRLGRYEE--------ALADYEQALELD 72

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 400286385 379 QAsltrdksinslkklvlrklrrkalDLESLSLLGFVYKLEGNMNEALEYYERALRLAADF 439
Cdd:COG0457   73 PD------------------------DAEALNNLGLALQALGRYEEALEDYDKALELDPDD 109
TPR_12 pfam13424
Tetratricopeptide repeat;
23-96 9.36e-06

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 43.53  E-value: 9.36e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 400286385   23 IHNLLAYVKHLKGQNEEALKSLKEAENLMQEEHDNQaNVRSLVTWGNFAWMYYHMGRLAEAQTYLDKVENICKK 96
Cdd:pfam13424   5 ALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPD-HPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
36-248 1.04e-05

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 46.45  E-value: 1.04e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385  36 QNEEALKSLKEAENLMQEEHDN-QANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKVENICKKLSNPFRYRmecpeidcee 114
Cdd:COG4785   44 LALALAAAALAAAALAAERIDRaLALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNR---------- 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 115 GWALLKCGgkNYERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNhkpfsllpLRQAVRLNPDNGYIKVLLAL 194
Cdd:COG4785  114 GLAYLLLG--DYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIAD--------LEKALELDPNDPERALWLYL 183

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 400286385 195 klqdegqeAEGEKYIEEALANMSSQTyvfryaAKFYRRKGSVDKALELLKKALQ 248
Cdd:COG4785  184 --------AERKLDPEKALALLLEDW------ATAYLLQGDTEEARELFKLALA 223
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
175-251 1.17e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 43.62  E-value: 1.17e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 400286385 175 LRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYiEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETP 251
Cdd:COG3063   15 YEKALELDPDNADALNNLGLLLLEQGRYDEAIAL-EKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDP 90
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 36-275 1.81e-05

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 46.90  E-value: 1.81e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385   36 QNEEALKSL--KEAENLMQEE-HDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKVENICKKLSNPFRYRMECPeidc 112
Cdd:TIGR00990 230 QSAQAVERLlkKFAESKAKEIlETKPENLPSVTFVGNYLQSFRPKPRPAGLEDSNELDEETGNGQLQLGLKSPESK---- 305

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385  113 eegwallkcGGKNYERAKACFEKVLEVDPENPessagYAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNP--DNGYIKv 190
Cdd:TIGR00990 306 ---------ADESYEEAARAFEKALDLGKLGE-----KEAIALNLRGTFKCLKGKHLEALADLSKSIELDPrvTQSYIK- 370

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385  191 lLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIG-LCYKAQMI 269
Cdd:TIGR00990 371 -RASMNLELGDPDKAEEDFDKALKLNSEDPDIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDFIFSHIQLGvTQYKEGSI 449


                  ....*.
gi 400286385  270 QIKEAT 275
Cdd:TIGR00990 450 ASSMAT 455
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 238-381 2.20e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 43.84  E-value: 2.20e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 238 KALELLKKALQETPTSVLLHHQIGLCYKAQmiqikeatkgqprGQNREkldkmirsAIFHFESAVEKKPTFEVAHLDLAR 317
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRL-------------GRYDE--------ALAAYEKALRLDPDNADALLDLAE 59

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 400286385 318 MYIEAGNHRKAEENFQKLLCMKPvveeTMQDIHFHYGRFQEFQKKSDvNAIIHYLKAIKIEQAS 381
Cdd:COG4235   60 ALLAAGDTEEAEELLERALALDP----DNPEALYLLGLAAFQQGDYA-EAIAAWQKLLALLPAD 118
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 292-439 8.66e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 42.49  E-value: 8.66e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 292 RSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKPvvEETmqDIHFHYGRFQEFQKKSDvNAIIHY 371
Cdd:COG4783   21 DEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDP--DEP--EARLNLGLALLKAGDYD-EALALL 95

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 400286385 372 LKAIKIEQAsltrdksinslkklvlrklrrkalDLESLSLLGFVYKLEGNMNEALEYYERALRLAADF 439
Cdd:COG4783   96 EKALKLDPE------------------------HPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
201-434 1.03e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 43.37  E-value: 1.03e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 201 QEAEGEKYIEEALANMSSQTYVFRYAAkfYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYkaqmiqikeatkgqpr 280
Cdd:COG4785   56 AALAAERIDRALALPDLAQLYYERGVA--YDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAY---------------- 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 281 gQNREKLDKmirsAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKllcmkpvveetmqdihfhygrFQEFQ 360
Cdd:COG4785  118 -LLLGDYDA----ALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEK---------------------ALELD 171

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 400286385 361 KKSDVNAIIHYlkaikieqasltrdksinslkkLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERALR 434
Cdd:COG4785  172 PNDPERALWLY----------------------LAERKLDPEKALALLLEDWATAYLLQGDTEEARELFKLALA 223
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 133-436 1.50e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 44.30  E-value: 1.50e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385  133 FEKVLEVDPENPESSAGYAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEA 212
Cdd:TIGR02917 106 FQQVLDELPGKTLLDDEGAAELLALRGLAYLGLGQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEV 185

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385  213 LANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHhqiglcYKAQMIQIKEatkgqprgQNREKLDKmir 292
Cdd:TIGR02917 186 LTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVL------LALATILIEA--------GEFEEAEK--- 248

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385  293 saifHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKPVVEETMQ---DIHFHYGRFQefQKKSDVNAII 369
Cdd:TIGR02917 249 ----HADALLKKAPNSPLAHYLKALVDFQKKNYEDARETLQDALKSAPEYLPALLlagASEYQLGNLE--QAYQYLNQIL 322

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 400286385  370 HYL----KAIKIEQASLTRDKSINSLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERALRLA 436
Cdd:TIGR02917 323 KYApnshQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELD 393
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 20-143 1.31e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 39.02  E-value: 1.31e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385  20 SVGIHNLLAYVKHLKGQNEEALKSLKEAENLMQEEHDnqanvrslvTWGNFAWMYYHMGRLAEAQTYLDKVenickklsn 99
Cdd:COG4783   37 NPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPE---------ARLNLGLALLKAGDYDEALALLEKA--------- 98

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 400286385 100 pFRYRMECPEIDCEEGWALLKCGgkNYERAKACFEKVLEVDPEN 143
Cdd:COG4783   99 -LKLDPEHPEAYLRLARAYRALG--RPDEAIAALEKALELDPDD 139
TPR_1 pfam00515
Tetratricopeptide repeat;
407-439 1.46e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 35.86  E-value: 1.46e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 400286385  407 ESLSLLGFVYKLEGNMNEALEYYERALRLAADF 439
Cdd:pfam00515   2 KALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 407-439 2.00e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 35.50  E-value: 2.00e-03
                           10        20        30
                   ....*....|....*....|....*....|...
gi 400286385   407 ESLSLLGFVYKLEGNMNEALEYYERALRLAADF 439
Cdd:smart00028   2 EALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
319-438 2.94e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 37.07  E-value: 2.94e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 319 YIEAGNHRKAEENFQKLLCMKPvveeTMQDIHFHYGRFQEFQKKSDvnaiihylKAIKIEQAsltrdksinslkklvlrk 398
Cdd:COG3063    2 YLKLGDLEEAEEYYEKALELDP----DNADALNNLGLLLLEQGRYD--------EAIALEKA------------------ 51

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 400286385 399 LRRKALDLESLSLLGFVYKLEGNMNEALEYYERALRLAAD 438
Cdd:COG3063   52 LKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDPS 91
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 311-439 2.98e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 37.86  E-value: 2.98e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 311 AHLDLARMYIEAGNHRKAEENFQKLLCMKPVVEETMQ---DIHFHYGRFQEfqkksdvnAIIHYLKAIKIEQAsltrdks 387
Cdd:COG4783    6 ALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFAllgEILLQLGDLDE--------AIVLLHEALELDPD------- 70

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 400286385 388 inslkklvlrklrrkalDLESLSLLGFVYKLEGNMNEALEYYERALRLAADF 439
Cdd:COG4783   71 -----------------EPEARLNLGLALLKAGDYDEALALLEKALKLDPEH 105
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
23-211 3.70e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 38.83  E-value: 3.70e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385  23 IHNLLAYVKHLKGQNEEALKSLKEAENLMQEEHDnqanvrslvTWGNFAWMYYHMGRLAEAQTYLDKVENICKKLSNPFR 102
Cdd:COG0457   78 ALNNLGLALQALGRYEEALEDYDKALELDPDDAE---------ALYNLGLALLELGRYDEAIEAYERALELDPDDADALY 148

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385 103 YRmecpeidceeGWALLKCGgkNYERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNHKPFSLLPLRQAVRLN 182
Cdd:COG0457  149 NL----------GIALEKLG--RYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTL 216

                        170       180
                 ....*....|....*....|....*....
gi 400286385 183 PDNGYIKVLLALKLQDEGQEAEGEKYIEE 211
Cdd:COG0457  217 AALAELLLLALALLLALRLAALALYQYRA 245
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 38-163 5.88e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 37.25  E-value: 5.88e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 400286385  38 EEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKVENICKKLSNPFRYRmecpeidceeGWA 117
Cdd:COG5010   28 EAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNL----------ALL 97

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 400286385 118 LLKCGgkNYERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLA 163
Cdd:COG5010   98 YSRSG--DKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEA 141
TPR_12 pfam13424
Tetratricopeptide repeat;
64-142 6.31e-03

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 35.44  E-value: 6.31e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 400286385   64 LVTWGNFAWMYYHMGRLAEAQTYLDKVENICKKLSNPFRYRmecpEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPE 142
Cdd:pfam13424   3 ATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPL----TATTLLNLGRLYLELGRYEEALELLERALALAEK 77
TPR_19 pfam14559
Tetratricopeptide repeat;
288-330 9.98e-03

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 34.48  E-value: 9.98e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 400286385  288 DKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEE 330
Cdd:pfam14559   1 EGDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEA 43
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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