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Conserved domains on  [gi|399124792|ref|NP_001257720|]
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putative transferase CAF17 homolog, mitochondrial isoform 2 precursor [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GcvT super family cl43132
Glycine cleavage system protein T (aminomethyltransferase) [Amino acid transport and ...
 59-113 1.03e-04

Glycine cleavage system protein T (aminomethyltransferase) [Amino acid transport and metabolism]; Glycine cleavage system protein T (aminomethyltransferase) is part of the Pathway/BioSystem: Glycine cleavage


The actual alignment was detected with superfamily member COG0404:

Pssm-ID: 440173 [Multi-domain]  Cd Length: 372  Bit Score: 42.76  E-value: 1.03e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 399124792  59 VRVRGPDAAPFLLGLSTNelPLSGPPTGaaqpsaRAAYAHFLNVQGRTLYDVILY 113
Cdd:COG0404   58 IEVTGPDAAAFLDRLVTN--DVSKLKPG------RARYTLMLNEDGGIIDDLTVY 104
 
Name Accession Description Interval E-value
GcvT COG0404
Glycine cleavage system protein T (aminomethyltransferase) [Amino acid transport and ...
 59-113 1.03e-04

Glycine cleavage system protein T (aminomethyltransferase) [Amino acid transport and metabolism]; Glycine cleavage system protein T (aminomethyltransferase) is part of the Pathway/BioSystem: Glycine cleavage


Pssm-ID: 440173 [Multi-domain]  Cd Length: 372  Bit Score: 42.76  E-value: 1.03e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 399124792  59 VRVRGPDAAPFLLGLSTNelPLSGPPTGaaqpsaRAAYAHFLNVQGRTLYDVILY 113
Cdd:COG0404   58 IEVTGPDAAAFLDRLVTN--DVSKLKPG------RARYTLMLNEDGGIIDDLTVY 104
GCV_T pfam01571
Aminomethyltransferase folate-binding domain; This is a family of glycine cleavage T-proteins, ...
 59-115 1.10e-04

Aminomethyltransferase folate-binding domain; This is a family of glycine cleavage T-proteins, part of the glycine cleavage multienzyme complex (GCV) found in bacteria and the mitochondria of eukaryotes. GCV catalyzes the catabolism of glycine in eukaryotes. The T-protein is an aminomethyl transferase.


Pssm-ID: 460255  Cd Length: 254  Bit Score: 42.19  E-value: 1.10e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 399124792   59 VRVRGPDAAPFLLGLSTNElpLSGPPTGaaqpsaRAAYAHFLNVQGRTLYDVILYGL 115
Cdd:pfam01571  50 IEVSGPDAAAFLQRLTTND--VSKLKPG------RATYTLMLNERGGVIDDLTVYRL 98
gcvT PRK00389
glycine cleavage system aminomethyltransferase GcvT;
59-113 6.45e-03

glycine cleavage system aminomethyltransferase GcvT;


Pssm-ID: 234742 [Multi-domain]  Cd Length: 359  Bit Score: 37.02  E-value: 6.45e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 399124792  59 VRVRGPDAAPFLLGLSTNElpLSGPPTGAAQpsaraaYAHFLNVQGRTLYDVILY 113
Cdd:PRK00389  55 VDVTGPDALAFLQYLLAND--VSKLKPGKAQ------YTCMLNEDGGVIDDLIVY 101
 
Name Accession Description Interval E-value
GcvT COG0404
Glycine cleavage system protein T (aminomethyltransferase) [Amino acid transport and ...
 59-113 1.03e-04

Glycine cleavage system protein T (aminomethyltransferase) [Amino acid transport and metabolism]; Glycine cleavage system protein T (aminomethyltransferase) is part of the Pathway/BioSystem: Glycine cleavage


Pssm-ID: 440173 [Multi-domain]  Cd Length: 372  Bit Score: 42.76  E-value: 1.03e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 399124792  59 VRVRGPDAAPFLLGLSTNelPLSGPPTGaaqpsaRAAYAHFLNVQGRTLYDVILY 113
Cdd:COG0404   58 IEVTGPDAAAFLDRLVTN--DVSKLKPG------RARYTLMLNEDGGIIDDLTVY 104
GCV_T pfam01571
Aminomethyltransferase folate-binding domain; This is a family of glycine cleavage T-proteins, ...
 59-115 1.10e-04

Aminomethyltransferase folate-binding domain; This is a family of glycine cleavage T-proteins, part of the glycine cleavage multienzyme complex (GCV) found in bacteria and the mitochondria of eukaryotes. GCV catalyzes the catabolism of glycine in eukaryotes. The T-protein is an aminomethyl transferase.


Pssm-ID: 460255  Cd Length: 254  Bit Score: 42.19  E-value: 1.10e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 399124792   59 VRVRGPDAAPFLLGLSTNElpLSGPPTGaaqpsaRAAYAHFLNVQGRTLYDVILYGL 115
Cdd:pfam01571  50 IEVSGPDAAAFLQRLTTND--VSKLKPG------RATYTLMLNERGGVIDDLTVYRL 98
gcvT PRK00389
glycine cleavage system aminomethyltransferase GcvT;
59-113 6.45e-03

glycine cleavage system aminomethyltransferase GcvT;


Pssm-ID: 234742 [Multi-domain]  Cd Length: 359  Bit Score: 37.02  E-value: 6.45e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 399124792  59 VRVRGPDAAPFLLGLSTNElpLSGPPTGAAQpsaraaYAHFLNVQGRTLYDVILY 113
Cdd:PRK00389  55 VDVTGPDALAFLQYLLAND--VSKLKPGKAQ------YTCMLNEDGGVIDDLIVY 101
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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